Nicholas Harden - Publications

Affiliations: 
Molecular Biology and Biochemistry Simon Fraser University, Burnaby, British Columbia, Canada 
Area:
Biochemistry, Molecular Biology

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wang SJH, Sinclair DAR, Kim HY, Kinsey SD, Yoo B, Shih CRY, Wong KKL, Krieger C, Harden N, Verheyen EM. Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure and function. Plos One. 15: e0221006. PMID 32187190 DOI: 10.1371/Journal.Pone.0221006  0.469
2017 Reed B, Harden N. Studying Nonproliferative Roles for Egfr Signaling in Tissue Morphogenesis Using Dorsal Closure of the Drosophila Embryo. Methods in Molecular Biology (Clifton, N.J.). 1652: 229-256. PMID 28791646 DOI: 10.1007/978-1-4939-7219-7_16  0.38
2017 Harden N. New Insights from Drosophila into the Regulation of EGFR Signaling. Methods in Molecular Biology (Clifton, N.J.). 1652: 37-42. PMID 28791632 DOI: 10.1007/978-1-4939-7219-7_2  0.335
2016 Harden N, Wang SJ, Krieger C. Making the connection - shared molecular machinery and evolutionary links underlie the formation and plasticity of occluding junctions and synapses. Journal of Cell Science. 129: 3067-76. PMID 27528207 DOI: 10.1242/Jcs.186627  0.579
2016 Conder R, Yu H, Zahedi B, Harden N. Corrigendum to "The serine/threonine kinase dPak is required for polarized assembly of F-actin bundles and apical-basal polarity in the Drosophila follicular epithelium"(Dev. Biol. 305 (2007) 470-482). Developmental Biology. PMID 27155223 DOI: 10.1016/J.Ydbio.2016.04.029  0.367
2016 Krieger C, Wang SJ, Yoo SH, Harden N. Adducin at the Neuromuscular Junction in Amyotrophic Lateral Sclerosis: Hanging on for Dear Life. Frontiers in Cellular Neuroscience. 10: 11. PMID 26858605 DOI: 10.3389/Fncel.2016.00011  0.578
2015 Wang S, Yoo S, Kim HY, Wang M, Zheng C, Parkhouse W, Krieger C, Harden N. Detection of in situ protein-protein complexes at the Drosophila larval neuromuscular junction using proximity ligation assay. Journal of Visualized Experiments : Jove. 52139. PMID 25650626 DOI: 10.3791/52139  0.574
2015 Vlachos S, Jangam S, Conder R, Chou M, Nystul T, Harden N. A Pak-regulated cell intercalation event leading to a novel radial cell polarity is involved in positioning of the follicle stem cell niche in the Drosophila ovary. Development (Cambridge, England). 142: 82-91. PMID 25516970 DOI: 10.1242/Dev.111039  0.393
2014 Wang SJ, Tsai A, Wang M, Yoo S, Kim HY, Yoo B, Chui V, Kisiel M, Stewart B, Parkhouse W, Harden N, Krieger C. Phospho-regulated Drosophila adducin is a determinant of synaptic plasticity in a complex with Dlg and PIP2 at the larval neuromuscular junction. Biology Open. 3: 1196-206. PMID 25416060 DOI: 10.1242/Bio.20148342  0.6
2013 Shen W, Chen X, Cormier O, Cheng DC, Reed B, Harden N. Modulation of morphogenesis by Egfr during dorsal closure in Drosophila. Plos One. 8: e60180. PMID 23579691 DOI: 10.1371/Journal.Pone.0060180  0.389
2011 Wang S, Yang J, Tsai A, Kuca T, Sanny J, Lee J, Dong K, Harden N, Krieger C. Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane. Developmental Biology. 357: 392-403. PMID 21791202 DOI: 10.1016/J.Ydbio.2011.07.010  0.622
2011 Vlachos S, Harden N. Genetic evidence for antagonism between Pak protein kinase and Rho1 small GTPase signaling in regulation of the actin cytoskeleton during Drosophila oogenesis. Genetics. 187: 501-12. PMID 21098722 DOI: 10.1534/Genetics.110.120998  0.448
2010 Bahri S, Wang S, Conder R, Choy J, Vlachos S, Dong K, Merino C, Sigrist S, Molnar C, Yang X, Manser E, Harden N. The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation. Development (Cambridge, England). 137: 2023-32. PMID 20501591 DOI: 10.1242/Jcs075242  0.575
2009 Fricke R, Gohl C, Dharmalingam E, Grevelhörster A, Zahedi B, Harden N, Kessels M, Qualmann B, Bogdan S. Drosophila Cip4/Toca-1 integrates membrane trafficking and actin dynamics through WASP and SCAR/WAVE. Current Biology : Cb. 19: 1429-37. PMID 19716703 DOI: 10.1016/J.Cub.2009.07.058  0.375
2008 Zahedi B, Shen W, Xu X, Chen X, Mahey M, Harden N. Leading edge-secreted Dpp cooperates with ACK-dependent signaling from the amnioserosa to regulate myosin levels during dorsal closure. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2936-46. PMID 18816840 DOI: 10.1002/Dvdy.21722  0.452
2007 Conder R, Yu H, Zahedi B, Harden N. The serine/threonine kinase dPak is required for polarized assembly of F-actin bundles and apical-basal polarity in the Drosophila follicular epithelium. Developmental Biology. 305: 470-82. PMID 17383630 DOI: 10.1016/J.Ydbio.2007.02.034  0.409
2006 Sanny J, Chui V, Langmann C, Pereira C, Zahedi B, Harden N. Drosophila RhoGAP68F is a putative GTPase activating protein for RhoA participating in gastrulation. Development Genes and Evolution. 216: 543-50. PMID 16609869 DOI: 10.1007/S00427-006-0067-6  0.478
2005 Tsuda M, Langmann C, Harden N, Aigaki T. The RING-finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila. Embo Reports. 6: 1082-7. PMID 16179944 DOI: 10.1038/Sj.Embor.7400537  0.365
2004 Conder R, Yu H, Ricos M, Hing H, Chia W, Lim L, Harden N. dPak is required for integrity of the leading edge cytoskeleton during Drosophila dorsal closure but does not signal through the JNK cascade. Developmental Biology. 276: 378-90. PMID 15581872 DOI: 10.1016/J.Ydbio.2004.08.044  0.444
2003 Wei HC, Sanny J, Shu H, Baillie DL, Brill JA, Price JV, Harden N. The Sac1 lipid phosphatase regulates cell shape change and the JNK cascade during dorsal closure in Drosophila. Current Biology : Cb. 13: 1882-7. PMID 14588244 DOI: 10.1016/J.Cub.2003.09.056  0.458
2003 Schenck A, Bardoni B, Langmann C, Harden N, Mandel JL, Giangrande A. CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein. Neuron. 38: 887-98. PMID 12818175 DOI: 10.1016/S0896-6273(03)00354-4  0.424
2002 Harden N. Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation; Research in Biological Diversity. 70: 181-203. PMID 12147138 DOI: 10.1046/J.1432-0436.2002.700408.X  0.453
2002 Sem KP, Zahedi B, Tan I, Deak M, Lim L, Harden N. ACK family tyrosine kinase activity is a component of Dcdc42 signaling during dorsal closure in Drosophila melanogaster. Molecular and Cellular Biology. 22: 3685-97. PMID 11997505 DOI: 10.1128/Mcb.22.11.3685-3697.2002  0.461
2002 Harden N, Ricos M, Yee K, Sanny J, Langmann C, Yu H, Chia W, Lim L. Drac1 and Crumbs participate in amnioserosa morphogenesis during dorsal closure in Drosophila. Journal of Cell Science. 115: 2119-29. PMID 11973353  0.345
1999 Hing H, Xiao J, Harden N, Lim L, Zipursky SL. Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila. Cell. 97: 853-63. PMID 10399914 DOI: 10.1016/S0092-8674(00)80798-9  0.4
1999 Harden N, Ricos M, Ong YM, Chia W, Lim L. Participation of small GTPases in dorsal closure of the Drosophila embryo: distinct roles for Rho subfamily proteins in epithelial morphogenesis. Journal of Cell Science. 112: 273-84. PMID 9885281  0.444
1998 Crawford JM, Harden N, Leung T, Lim L, Kiehart DP. Cellularization in Drosophila melanogaster is disrupted by the inhibition of rho activity and the activation of Cdc42 function. Developmental Biology. 204: 151-64. PMID 9851849 DOI: 10.1006/Dbio.1998.9061  0.441
1996 Harden N, Lee J, Loh HY, Ong YM, Tan I, Leung T, Manser E, Lim L. A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures. Molecular and Cellular Biology. 16: 1896-908. PMID 8628256 DOI: 10.1128/Mcb.16.5.1896  0.542
1995 Harden N, Loh HY, Chia W, Lim L. A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila. Development (Cambridge, England). 121: 903-14. PMID 7720592  0.366
1993 Harden N, Yap SF, Chiam MA, Lim L. A Drosophila gene encoding a protein with similarity to diacylglycerol kinase is expressed in specific neurons. The Biochemical Journal. 289: 439-44. PMID 8380995 DOI: 10.1042/Bj2890439  0.366
1991 Ahmed S, Kozma R, Lee J, Monfries C, Harden N, Lim L. The cysteine-rich domain of human proteins, neuronal chimaerin, protein kinase C and diacylglycerol kinase binds zinc. Evidence for the involvement of a zinc-dependent structure in phorbol ester binding. The Biochemical Journal. 280: 233-41. PMID 1660266 DOI: 10.1042/Bj2800233  0.391
Show low-probability matches.