Timothy L. Reudelhuber - Publications

Affiliations: 
Université de Montréal, Montréal, Canada 
Area:
Biochemistry

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Martini AG, Xa LK, Lacombe MJ, Blanchet-Cohen A, Mercure C, Haibe-Kains B, Friesema EC, van den Meiracker AH, Gross KW, Azizi M, Corvol P, Nguyen G, Reudelhuber TL, Danser AH. Transcriptome Analysis of Human Reninomas as an Approach to Understanding Juxtaglomerular Cell Biology. Hypertension (Dallas, Tex. : 1979). PMID 28396539 DOI: 10.1161/Hypertensionaha.117.09179  0.391
2014 Cardin S, Scott-Boyer MP, Praktiknjo S, Jeidane S, Picard S, Reudelhuber TL, Deschepper CF. Differences in cell-type-specific responses to angiotensin II explain cardiac remodeling differences in C57BL/6 mouse substrains. Hypertension. 64: 1040-6. PMID 25069667 DOI: 10.1161/Hypertensionaha.114.04067  0.323
2014 Xa LK, Lacombe MJ, Mercure C, Lazure C, Reudelhuber TL. General lysosomal hydrolysis can process prorenin accurately. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R505-13. PMID 24965790 DOI: 10.1152/ajpregu.00467.2013  0.41
2014 Burger D, Reudelhuber TL, Mahajan A, Chibale K, Sturrock ED, Touyz RM. Effects of a domain-selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertension. Clinical Science (London, England : 1979). 127: 57-63. PMID 24506807 DOI: 10.1042/Cs20130808  0.317
2010 Shenoy V, Ferreira AJ, Qi Y, Fraga-Silva RA, Díez-Freire C, Dooies A, Jun JY, Sriramula S, Mariappan N, Pourang D, Venugopal CS, Francis J, Reudelhuber T, Santos RA, Patel JM, et al. The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 182: 1065-72. PMID 20581171 DOI: 10.1164/Rccm.200912-1840Oc  0.329
2010 Reudelhuber TL. Prorenin, Renin, and their receptor: moving targets. Hypertension. 55: 1071-4. PMID 20212275 DOI: 10.1161/Hypertensionaha.108.120279  0.362
2010 Mercure C, Lacombe MJ, Khazaie K, Reudelhuber TL. Cathepsin B is not the processing enzyme for mouse prorenin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R1212-6. PMID 20164204 DOI: 10.1152/ajpregu.00830.2009  0.329
2010 Ferreira AJ, Castro CH, Guatimosim S, Almeida PW, Gomes ER, Dias-Peixoto MF, Alves MN, Fagundes-Moura CR, Rentzsch B, Gava E, Almeida AP, Guimarães AM, Kitten GT, Reudelhuber T, Bader M, et al. Attenuation of isoproterenol-induced cardiac fibrosis in transgenic rats harboring an angiotensin-(1-7)-producing fusion protein in the heart. Therapeutic Advances in Cardiovascular Disease. 4: 83-96. PMID 20051448 DOI: 10.1177/1753944709353426  0.312
2009 Reudelhuber TL. Truncated prorenin comes up ... short. Hypertension. 54: 1216-7. PMID 19822794 DOI: 10.1161/Hypertensionaha.109.140392  0.379
2009 Dikeakos JD, Di Lello P, Lacombe MJ, Ghirlando R, Legault P, Reudelhuber TL, Omichinski JG. Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease. Proceedings of the National Academy of Sciences of the United States of America. 106: 7408-13. PMID 19376969 DOI: 10.1073/Pnas.0809576106  0.402
2008 Mercure C, Yogi A, Callera GE, Aranha AB, Bader M, Ferreira AJ, Santos RA, Walther T, Touyz RM, Reudelhuber TL. Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart. Circulation Research. 103: 1319-26. PMID 18845809 DOI: 10.1161/Circresaha.108.184911  0.333
2008 Yogi A, Mercure C, Touyz J, Callera GE, Montezano AC, Aranha AB, Tostes RC, Reudelhuber T, Touyz RM. Renal redox-sensitive signaling, but not blood pressure, is attenuated by Nox1 knockout in angiotensin II-dependent chronic hypertension. Hypertension (Dallas, Tex. : 1979). 51: 500-6. PMID 18195161 DOI: 10.1161/Hypertensionaha.107.103192  0.329
2007 Dikeakos JD, Mercure C, Lacombe MJ, Seidah NG, Reudelhuber TL. PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism. The Febs Journal. 274: 4094-102. PMID 17645548 DOI: 10.1111/J.1742-4658.2007.05937.X  0.414
2007 Rabah N, Gauthier D, Dikeakos JD, Reudelhuber TL, Lazure C. The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro. The Febs Journal. 274: 3482-91. PMID 17565604 DOI: 10.1111/J.1742-4658.2007.05883.X  0.419
2007 Dikeakos JD, Reudelhuber TL. Sending proteins to dense core secretory granules: still a lot to sort out. The Journal of Cell Biology. 177: 191-6. PMID 17438078 DOI: 10.1083/Jcb.200701024  0.362
2007 Dikeakos JD, Lacombe MJ, Mercure C, Mireuta M, Reudelhuber TL. A hydrophobic patch in a charged alpha-helix is sufficient to target proteins to dense core secretory granules. The Journal of Biological Chemistry. 282: 1136-43. PMID 17092937 DOI: 10.1074/Jbc.M605718200  0.37
2006 Reudelhuber TL. A place in our hearts for the lowly angiotensin 1-7 peptide? Hypertension. 47: 811-5. PMID 16520407 DOI: 10.1161/01.Hyp.0000209020.69734.73  0.341
2005 Reudelhuber TL. The continuing saga of the AT2 receptor: a case of the good, the bad, and the innocuous. Hypertension. 46: 1261-2. PMID 16286568 DOI: 10.1161/01.Hyp.0000193498.07087.83  0.313
2005 Lacombe MJ, Mercure C, Dikeakos JD, Reudelhuber TL. Modulation of secretory granule-targeting efficiency by cis and trans compounding of sorting signals. The Journal of Biological Chemistry. 280: 4803-7. PMID 15569678 DOI: 10.1074/Jbc.M408658200  0.348
2004 Lochard N, Thibault G, Silversides DW, Touyz RM, Reudelhuber TL. Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist. Circulation Research. 94: 1451-7. PMID 15117826 DOI: 10.1161/01.Res.0000130654.56599.40  0.332
2004 Amiri F, Iglarz M, Virdis A, Neves MF, Lavoie M, Touyz RM, Reudelhuber TL, Schiffrin EL. CHARACTERIZATION OF A NEW MURINE TRANSGENIC MODEL OF ENDOTHELIAL CELL HUMAN ENDOTHELIN-1 OVEREXPRESSION.4 Journal of Hypertension. 22: S30. DOI: 10.1097/00004872-200402001-00112  0.332
2003 Zahabi A, Picard S, Fortin N, Reudelhuber TL, Deschepper CF. Expression of constitutively active guanylate cyclase in cardiomyocytes inhibits the hypertrophic effects of isoproterenol and aortic constriction on mouse hearts. The Journal of Biological Chemistry. 278: 47694-9. PMID 14500707 DOI: 10.1074/Jbc.M309661200  0.318
2002 Prescott G, Silversides DW, Reudelhuber TL. Tissue activity of circulating prorenin. American Journal of Hypertension. 15: 280-5. PMID 11939621 DOI: 10.1016/S0895-7061(01)02284-1  0.375
2001 van Kats JP, Methot D, Paradis P, Silversides DW, Reudelhuber TL. Use of a biological peptide pump to study chronic peptide hormone action in transgenic mice. Direct and indirect effects of angiotensin II on the heart. The Journal of Biological Chemistry. 276: 44012-7. PMID 11551931 DOI: 10.1074/Jbc.M106132200  0.343
2001 Methot D, VanKats JP, Lochard N, Tremblay F, Silversides DW, Reudelhuber TL. Development and application of a biological peptide pump for the study of the in vivo actions of angiotensin peptides American Journal of Hypertension. 14. PMID 11411764 DOI: 10.1016/S0895-7061(01)02068-4  0.333
2001 Methot D, Reudelhuber TL. Knockout of renin-angiotensin system genes: Effects on vascular development Current Hypertension Reports. 3: 68-73. PMID 11177711 DOI: 10.1007/S11906-001-0083-X  0.3
2000 Jutras I, Seidah NG, Reudelhuber TL. A predicted alpha -helix mediates targeting of the proprotein convertase PC1 to the regulated secretory pathway. The Journal of Biological Chemistry. 275: 40337-43. PMID 11006274 DOI: 10.1074/Jbc.M004757200  0.727
2000 Eijnden MMvd, Sluiter W, Derkx FH, Reudelhuber TL, Schalekamp MA, Danser AH. Human Endothelial Cells Bind and Activate Noncleavable Prorenin Hypertension. 36: 695-695. DOI: 10.1161/01.Hyp.36.Suppl_1.695-D  0.408
2000 Kats JPv, Silversides DW, Reudelhuber TL. Dissociation of Direct and Indirect Effects of Angiotensin II on the Heart Hypertension. 36: 683-684. DOI: 10.1161/01.Hyp.36.Suppl_1.683-D  0.306
1999 Methot D, Silversides DW, Reudelhuber TL. In vivo enzymatic assay reveals catalytic activity of the human renin precursor in tissues Circulation Research. 84: 1067-1072. PMID 10325244  0.35
1999 Jutras I, Reudelhuber TL. Prorenin processing by cathepsin B in vitro and in transfected cells. Febs Letters. 443: 48-52. PMID 9928950 DOI: 10.1016/S0014-5793(98)01672-X  0.731
1998 Laflamme L, Brechler V, Reudelhuber TL, Gallo-Payet N, Deschepper CF. The renin-angiotensin system in hybrid NG108-15 cells. Renin gene is from mouse neuroblastoma, angiotensinogen and angiotensin-converting enzyme genes are of rat glioma origin Regulatory Peptides. 77: 9-15. PMID 9809791 DOI: 10.1016/S0167-0115(98)00025-1  0.406
1998 Reudelhuber TL, Brechler V, Jutras I, Mercure C, Methot D. Proteolytic and non-proteolytic activation of prorenin. Advances in Experimental Medicine and Biology. 436: 229-38. PMID 9561224 DOI: 10.1007/978-1-4615-5373-1_32  0.722
1998 Mercure C, Ramla D, Garcia R, Thibault G, Deschepper CF, Reudelhuber TL. Evidence for intracellular generation of angiotensin II in rat juxtaglomerular cells Febs Letters. 422: 395-399. PMID 9498824 DOI: 10.1016/S0014-5793(98)00052-0  0.454
1997 Jutras I, Seidah NG, Reudelhuber TL, Brechler V. Two activation states of the prohormone convertase PC1 in the secretory pathway. The Journal of Biological Chemistry. 272: 15184-8. PMID 9182540 DOI: 10.1074/Jbc.272.24.15184  0.742
1997 Methot D, LaPointe MC, Touyz RM, Yang XP, Carretero OA, Deschepper CF, Schiffrin EL, Thibault G, Reudelhuber TL. Tissue targeting of angiotensin peptides Journal of Biological Chemistry. 272: 12994-12999. PMID 9148907 DOI: 10.1074/Jbc.272.20.12994  0.383
1997 Laframboise M, Reudelhuber TL, Jutras I, Brechler V, Seidah NG, Day R, Gross KW, Deschepper CF. Prorenin activation and prohormone convertases in the mouse As4.1 cell line. Kidney International. 51: 104-9. PMID 8995723  0.735
1996 Mercure C, Jutras I, Day R, Seidah NG, Reudelhuber TL. Prohormone convertase PC5 is a candidate processing enzyme for prorenin in the human adrenal cortex. Hypertension. 28: 840-6. PMID 8901832 DOI: 10.1161/01.Hyp.28.5.840  0.721
1996 Canaff C, Brechler V, Reudelhuber TL, Thibault G. Secretory granule targeting of atrial natriuretic peptide correlates with its calcium-mediated aggregation Proceedings of the National Academy of Sciences of the United States of America. 93: 9483-9487. PMID 8790356 DOI: 10.1073/Pnas.93.18.9483  0.35
1996 Brechler V, Chu WN, Baxter JD, Thibault G, Reudelhuber TL. A protease processing site is essential for prorenin sorting to the regulated secretory pathway Journal of Biological Chemistry. 271: 20636-20640. PMID 8702811 DOI: 10.1074/Jbc.271.34.20636  0.463
1996 Touyz RM, Sventek P, Larivière R, Thibault G, Fareh J, Reudelhuber T, Schiffrin EL. Cytosolic calcium changes induced by angiotensin II in neonatal rat atrial and ventricular cardiomyocytes are mediated via angiotensin II subtype 1 receptors. Hypertension (Dallas, Tex. : 1979). 27: 1090-6. PMID 8621201 DOI: 10.1161/01.Hyp.27.5.1090  0.309
1995 Mercure C, Thibault G, Lussier-Cacan S, Davignon J, Schiffrin EL, Reudelhuber TL. Molecular analysis of human prorenin prosegment variants in vitro and in vivo Journal of Biological Chemistry. 270: 16355-16359. PMID 7608205 DOI: 10.1074/Jbc.270.27.16355  0.39
1994 Reudelhuber TL, Ramla D, Chiu L, Mercure C, Seidah NG. Proteolytic processing of human prorenin in renal and non-renal tissues Kidney International. 46: 1522-1524. PMID 7699995 DOI: 10.1038/Ki.1994.435  0.44
1993 Su Y, Reudelhuber TL. Molecular characterization of human prorenin isoelectric forms Journal of Hypertension. 11: 141-146. PMID 8385173 DOI: 10.1097/00004872-199302000-00005  0.369
1992 Baxter JD, Duncan K, Chu W, James MNG, Russell RB, Haidar MA, DeNoto FM, Hsueh W, Reudelhuber TL. Molecular biology of human renin and its gene Recent Progress in Hormone Research. 47: 211-257. PMID 1745821 DOI: 10.1016/B978-0-12-571147-0.50011-1  0.304
1990 Deschepper CF, Reudelhuber TL. Rat angiotensinogen is secreted only constitutively when transfected into AtT-20 cells Hypertension. 16: 147-153. PMID 2166001 DOI: 10.1161/01.Hyp.16.2.147  0.332
1990 Chu WN, Baxter JD, Reudelhuber TL. A targeting sequence for dense secretory granules resides in the active renin protein moiety of human preprorenin Molecular Endocrinology. 4: 1905-1913. PMID 2082189 DOI: 10.1210/Mend-4-12-1905  0.378
1989 Baxter JD, James MNG, Chu WN, Duncan K, Haidar MA, Carilli CT, Reudelhuber TL, Phil D. The molecular biology of human renin and its gene Yale Journal of Biology and Medicine. 62: 493-501. PMID 2697983  0.344
1987 Fritz LC, Haidar MA, Arfsten AE, Schilling JW, Carilli C, Shine J, Baxter JD, Reudelhuber TL. Human renin is correctly processed and targeted to the regulated secretory pathway in mouse pituitary AtT-20 cells Journal of Biological Chemistry. 262: 12409-12412. PMID 3305508  0.387
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