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Ted C. Pierson, Ph.D. - Publications

Affiliations: 
2002 Johns Hopkins University, Baltimore, MD 
Area:
Immunology
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108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Maciejewski S, Ruckwardt TJ, Morabito KM, Foreman BM, Burgomaster KE, Gordon DN, Pelc RS, DeMaso CR, Ko SY, Fisher BE, Yang ES, Nair D, Foulds KE, Todd JP, Kong WP, ... ... Pierson TC, et al. Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality. Science Translational Medicine. 12. PMID 32522807 DOI: 10.1126/Scitranslmed.Aaw9066  0.36
2020 Diamond MS, Pierson TC. The Challenges of Vaccine Development against a New Virus during a Pandemic. Cell Host & Microbe. 27: 699-703. PMID 32407708 DOI: 10.1016/J.Chom.2020.04.021  0.72
2020 Pierson TC, Diamond MS. The continued threat of emerging flaviviruses. Nature Microbiology. PMID 32367055 DOI: 10.1038/S41564-020-0714-0  0.72
2020 Chen GL, Coates EE, Plummer SH, Carter CA, Berkowitz N, Conan-Cibotti M, Cox JH, Beck A, O'Callahan M, Andrews C, Gordon IJ, Larkin B, Lampley R, Kaltovich F, Gall J, ... ... Pierson TC, et al. Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial. Jama. 323: 1369-1377. PMID 32286643 DOI: 10.1001/Jama.2020.2477  0.36
2019 Van Rompay KKA, Keesler RI, Ardeshir A, Watanabe J, Usachenko J, Singapuri A, Cruzen C, Bliss-Moreau E, Murphy AM, Yee JL, Webster H, Dennis M, Singh T, Heimsath H, Lemos D, ... ... Pierson TC, et al. DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes. Science Translational Medicine. 11. PMID 31852797 DOI: 10.1126/Scitranslmed.Aay2736  0.32
2019 Zhao H, Xu L, Bombardi R, Nargi R, Deng Z, Errico JM, Nelson CA, Dowd KA, Pierson TC, Crowe JE, Diamond MS, Fremont DH. Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. The Journal of Experimental Medicine. PMID 31757867 DOI: 10.1084/Jem.20191792  0.72
2019 Jagger BW, Dowd KA, Chen RE, Desai P, Foreman B, Burgomaster KE, Himansu S, Kong WP, Graham BS, Pierson TC, Diamond MS. Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice. The Journal of Infectious Diseases. PMID 31260518 DOI: 10.1093/Infdis/Jiz338  0.72
2019 Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE, Screaton GR, Diamond MS. Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice. Cell Reports. 26: 1585-1597.e4. PMID 30726740 DOI: 10.1016/J.Celrep.2019.01.052  0.72
2018 VanBlargan LA, Himansu S, Foreman BM, Ebel GD, Pierson TC, Diamond MS. An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections. Cell Reports. 25: 3382-3392.e3. PMID 30566864 DOI: 10.1016/J.Celrep.2018.11.082  0.72
2018 Goo L, Debbink K, Kose N, Sapparapu G, Doyle MP, Wessel AW, Richner JM, Burgomaster KE, Larman BC, Dowd KA, Diamond MS, Crowe JE, Pierson TC. A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions. Nature Microbiology. PMID 30455471 DOI: 10.1038/S41564-018-0283-7  0.72
2018 Diamond MS, Ledgerwood JE, Pierson TC. Zika Virus Vaccine Development: Progress in the Face of New Challenges. Annual Review of Medicine. PMID 30388054 DOI: 10.1146/Annurev-Med-040717-051127  0.72
2018 Pierson TC, Diamond MS. The emergence of Zika virus and its new clinical syndromes. Nature. 560: 573-581. PMID 30158602 DOI: 10.1038/S41586-018-0446-Y  0.72
2018 Frei JC, Wirchnianski AS, Govero J, Vergnolle O, Dowd KA, Pierson TC, Kielian M, Girvin ME, Diamond MS, Lai JR. Engineered Dengue Virus Domain III Proteins Elicit Cross-neutralizing Antibody Responses in Mice. Journal of Virology. PMID 29976679 DOI: 10.1128/Jvi.01023-18  0.72
2018 Goo L, DeMaso CR, Pelc RS, Ledgerwood JE, Graham BS, Kuhn RJ, Pierson TC. The Zika virus envelope protein glycan loop regulates virion antigenicity. Virology. 515: 191-202. PMID 29304471 DOI: 10.1016/J.Virol.2017.12.032  0.36
2017 Gaudinski MR, Houser KV, Morabito KM, Hu Z, Yamshchikov G, Rothwell RS, Berkowitz N, Mendoza F, Saunders JG, Novik L, Hendel CS, Holman LA, Gordon IJ, Cox JH, Edupuganti S, ... ... Pierson TC, et al. Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials. Lancet (London, England). PMID 29217376 DOI: 10.1016/S0140-6736(17)33105-7  0.36
2017 Shan C, Muruato AE, Jagger BW, Richner J, Nunes BTD, Medeiros DBA, Xie X, Nunes JGC, Morabito KM, Kong WP, Pierson TC, Barrett AD, Weaver SC, Rossi SL, Vasconcelos PFC, et al. A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage. Nature Communications. 8: 676. PMID 28939807 DOI: 10.1038/S41467-017-00737-8  0.72
2017 Richner JM, Jagger BW, Shan C, Fontes CR, Dowd KA, Cao B, Himansu S, Caine EA, Nunes BTD, Medeiros DBA, Muruato AE, Foreman BM, Luo H, Wang T, Barrett AD, ... ... Pierson TC, et al. Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease. Cell. 170: 273-283.e12. PMID 28708997 DOI: 10.1016/J.Cell.2017.06.040  0.72
2017 Richner JM, Himansu S, Dowd KA, Butler SL, Salazar V, Fox JM, Julander JG, Tang WW, Shresta S, Pierson TC, Ciaramella G, Diamond MS. Modified mRNA Vaccines Protect against Zika Virus Infection. Cell. 169: 176. PMID 28340344 DOI: 10.1016/J.Cell.2017.03.016  0.72
2017 Richner JM, Himansu S, Dowd KA, Butler SL, Salazar V, Fox JM, Julander JG, Tang WW, Shresta S, Pierson TC, Ciaramella G, Diamond MS. Modified mRNA Vaccines Protect against Zika Virus Infection. Cell. PMID 28222903 DOI: 10.1016/J.Cell.2017.02.017  0.72
2017 Goo L, VanBlargan LA, Dowd KA, Diamond MS, Pierson TC. A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis. Plos Pathogens. 13: e1006178. PMID 28207910 DOI: 10.1371/Journal.Ppat.1006178  0.72
2016 VanBlargan LA, Goo L, Pierson TC. Deconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and Immunity. Microbiology and Molecular Biology Reviews : Mmbr. 80: 989-1010. PMID 27784796 DOI: 10.1128/Mmbr.00024-15  0.32
2016 Goo L, Dowd KA, Lin TY, Mascola JR, Graham BS, Ledgerwood JE, Pierson TC. A virus-like particle vaccine elicits broad neutralizing antibody responses in humans to all Chikungunya virus genotypes. The Journal of Infectious Diseases. PMID 27655868 DOI: 10.1093/Infdis/Jiw431  0.36
2016 Speer SD, Pierson TC. Diagnostics for Zika virus on the horizon the immune response to Zika virus informs antibodybased diagnostics and therapeutics Science. 353: 750-751. PMID 27540152 DOI: 10.1126/science.aah6187  0.76
2016 Dowd KA, DeMaso CR, Pelc RS, Speer SD, Smith AR, Goo L, Platt DJ, Mascola JR, Graham BS, Mulligan MJ, Diamond MS, Ledgerwood JE, Pierson TC. Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype. Cell Reports. PMID 27481466 DOI: 10.1016/J.Celrep.2016.07.049  0.72
2016 Zhao H, Fernandez E, Dowd KA, Speer SD, Platt DJ, Gorman MJ, Govero J, Nelson CA, Pierson TC, Diamond MS, Fremont DH. Structural Basis of Zika Virus-Specific Antibody Protection. Cell. PMID 27475895 DOI: 10.1016/J.Cell.2016.07.020  0.76
2016 Mukherjee S, Sirohi D, Dowd KA, Chen Z, Diamond MS, Kuhn RJ, Pierson TC. Enhancing dengue virus maturation using a stable furin over-expressing cell line. Virology. 497: 33-40. PMID 27420797 DOI: 10.1016/J.Virol.2016.06.022  0.76
2016 Zhang R, Miner JJ, Gorman MJ, Rausch K, Ramage H, White JP, Zuiani A, Zhang P, Fernandez E, Zhang Q, Dowd KA, Pierson TC, Cherry S, Diamond MS. A CRISPR screen defines a signal peptide processing pathway required by flaviviruses. Nature. 535: 164-168. PMID 27383988 DOI: 10.1038/Nature18625  0.76
2016 Sirohi D, Chen Z, Sun L, Klose T, Pierson TC, Rossmann MG, Kuhn RJ. The 3.8 Å resolution cryo-EM structure of Zika virus. Science (New York, N.Y.). PMID 27033547 DOI: 10.1126/Science.Aaf5316  0.76
2015 Dowd KA, DeMaso CR, Pierson TC. Genotypic Differences in Dengue Virus Neutralization Are Explained by a Single Amino Acid Mutation That Modulates Virus Breathing. Mbio. 6: e01559-15. PMID 26530385 DOI: 10.1128/Mbio.01559-15  0.76
2015 Katzelnick LC, Fonville JM, Gromowski GD, Bustos Arriaga J, Green A, James SL, Lau L, Montoya M, Wang C, VanBlargan LA, Russell CA, Thu HM, Pierson TC, Buchy P, Aaskov JG, et al. Dengue viruses cluster antigenically but not as discrete serotypes. Science (New York, N.Y.). 349: 1338-43. PMID 26383952 DOI: 10.1126/Science.Aac5017  0.76
2015 Goo L, Pierson TC. Dengue virus: Bumps in the road to therapeutic antibodies. Nature. 524: 295-6. PMID 26289200 DOI: 10.1038/524295A  0.76
2015 Diamond MS, Pierson TC. Molecular Insight into Dengue Virus Pathogenesis and Its Implications for Disease Control. Cell. 162: 488-92. PMID 26232221 DOI: 10.1016/J.Cell.2015.07.005  0.76
2015 VanBlargan LA, Davis KA, Dowd KA, Akey DL, Smith JL, Pierson TC. Context-Dependent Cleavage of the Capsid Protein by the West Nile Virus Protease Modulates the Efficiency of Virus Assembly. Journal of Virology. 89: 8632-42. PMID 26063422 DOI: 10.1128/Jvi.01253-15  0.76
2015 Kuhn RJ, Dowd KA, Beth Post C, Pierson TC. Shake, rattle, and roll: Impact of the dynamics of flavivirus particles on their interactions with the host. Virology. 479: 508-517. PMID 25835729 DOI: 10.1016/J.Virol.2015.03.025  0.76
2015 Pierson TC, Diamond MS. A game of numbers: the stoichiometry of antibody-mediated neutralization of flavivirus infection. Progress in Molecular Biology and Translational Science. 129: 141-66. PMID 25595803 DOI: 10.1016/Bs.Pmbts.2014.10.005  0.76
2014 Pierson TC, Diamond MS. Vaccine Development as a Means to Control Dengue Virus Pathogenesis: Do We Know Enough? Annual Review of Virology. 1: 375-98. PMID 26958727 DOI: 10.1146/Annurev-Virology-031413-085453  0.72
2014 Chang LJ, Dowd KA, Mendoza FH, Saunders JG, Sitar S, Plummer SH, Yamshchikov G, Sarwar UN, Hu Z, Enama ME, Bailer RT, Koup RA, Schwartz RM, Akahata W, Nabel GJ, ... ... Pierson TC, et al. Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial. Lancet. 384: 2046-52. PMID 25132507 DOI: 10.1016/S0140-6736(14)61185-5  0.76
2014 Dowd KA, Mukherjee S, Kuhn RJ, Pierson TC. Combined effects of the structural heterogeneity and dynamics of flaviviruses on antibody recognition. Journal of Virology. 88: 11726-37. PMID 25078693 DOI: 10.1128/Jvi.01140-14  0.76
2014 Edeling MA, Austin SK, Shrestha B, Dowd KA, Mukherjee S, Nelson CA, Johnson S, Mabila MN, Christian EA, Rucker J, Pierson TC, Diamond MS, Fremont DH. Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement. Plos Pathogens. 10: e1004072. PMID 24743696 DOI: 10.1371/Journal.Ppat.1004072  0.76
2014 Mukherjee S, Dowd KA, Manhart CJ, Ledgerwood JE, Durbin AP, Whitehead SS, Pierson TC. Mechanism and significance of cell type-dependent neutralization of flaviviruses. Journal of Virology. 88: 7210-20. PMID 24741083 DOI: 10.1128/Jvi.03690-13  0.76
2014 Mukherjee S, Pierson TC, Dowd KA. Pseudo-infectious reporter virus particles for measuring antibody-mediated neutralization and enhancement of dengue virus infection. Methods in Molecular Biology (Clifton, N.J.). 1138: 75-97. PMID 24696332 DOI: 10.1007/978-1-4939-0348-1_6  0.76
2013 VanBlargan LA, Mukherjee S, Dowd KA, Durbin AP, Whitehead SS, Pierson TC. The type-specific neutralizing antibody response elicited by a dengue vaccine candidate is focused on two amino acids of the envelope protein. Plos Pathogens. 9: e1003761. PMID 24348242 DOI: 10.1371/Journal.Ppat.1003761  0.76
2013 Lee PD, Mukherjee S, Edeling MA, Dowd KA, Austin SK, Manhart CJ, Diamond MS, Fremont DH, Pierson TC. The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states. Journal of Virology. 87: 13729-40. PMID 24109224 DOI: 10.1128/Jvi.02340-13  0.76
2013 Balinsky CA, Schmeisser H, Ganesan S, Singh K, Pierson TC, Zoon KC. Nucleolin interacts with the dengue virus capsid protein and plays a role in formation of infectious virus particles. Journal of Virology. 87: 13094-106. PMID 24027323 DOI: 10.1128/JVI.00704-13  0.76
2013 Sukupolvi-Petty S, Brien JD, Austin SK, Shrestha B, Swayne S, Kahle K, Doranz BJ, Johnson S, Pierson TC, Fremont DH, Diamond MS. Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection. Journal of Virology. 87: 8826-42. PMID 23785205 DOI: 10.1128/Jvi.01314-13  0.76
2013 Pal P, Dowd KA, Brien JD, Edeling MA, Gorlatov S, Johnson S, Lee I, Akahata W, Nabel GJ, Richter MK, Smit JM, Fremont DH, Pierson TC, Heise MT, Diamond MS. Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus. Plos Pathogens. 9: e1003312. PMID 23637602 DOI: 10.1371/Journal.Ppat.1003312  0.76
2013 Pierson TC, Kielian M. Flaviviruses: braking the entering. Current Opinion in Virology. 3: 3-12. PMID 23352692 DOI: 10.1016/J.Coviro.2012.12.001  0.76
2013 Obara CJ, Dowd KA, Ledgerwood JE, Pierson TC. Impact of viral attachment factor expression on antibody-mediated neutralization of flaviviruses. Virology. 437: 20-7. PMID 23312596 DOI: 10.1016/J.Virol.2012.11.016  0.76
2012 Austin SK, Dowd KA, Shrestha B, Nelson CA, Edeling MA, Johnson S, Pierson TC, Diamond MS, Fremont DH. Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope. Plos Pathogens. 8: e1002930. PMID 23055922 DOI: 10.1371/Journal.Ppat.1002930  0.76
2012 Pierson TC, Yewdell JW. Measles immunometrics. Proceedings of the National Academy of Sciences of the United States of America. 109: 14724-5. PMID 22936050 DOI: 10.1073/Pnas.1212243109  0.76
2012 Pierson TC, Diamond MS. Degrees of maturity: the complex structure and biology of flaviviruses. Current Opinion in Virology. 2: 168-75. PMID 22445964 DOI: 10.1016/J.Coviro.2012.02.011  0.76
2012 Shrestha B, Austin SK, Dowd KA, Prasad AN, Youn S, Pierson TC, Fremont DH, Ebel GD, Diamond MS. Complex phenotypes in mosquitoes and mice associated with neutralization escape of a Dengue virus type 1 monoclonal antibody. Virology. 427: 127-34. PMID 22406169 DOI: 10.1016/J.Virol.2012.02.010  0.76
2012 Pierson TC, Kuhn RJ. Capturing a virus while it catches its breath. Structure (London, England : 1993). 20: 200-2. PMID 22325768 DOI: 10.1016/j.str.2012.01.014  0.76
2012 Lin TY, Dowd KA, Manhart CJ, Nelson S, Whitehead SS, Pierson TC. A novel approach for the rapid mutagenesis and directed evolution of the structural genes of west nile virus. Journal of Virology. 86: 3501-12. PMID 22258236 DOI: 10.1128/Jvi.06435-11  0.76
2011 Chen S, Chahar HS, Abraham S, Wu H, Pierson TC, Wang XA, Manjunath N. Ago-2-mediated slicer activity is essential for anti-flaviviral efficacy of RNAi. Plos One. 6: e27551. PMID 22102908 DOI: 10.1371/journal.pone.0027551  0.76
2011 Vogt MR, Dowd KA, Engle M, Tesh RB, Johnson S, Pierson TC, Diamond MS. Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms. Journal of Virology. 85: 11567-80. PMID 21917960 DOI: 10.1128/Jvi.05859-11  0.76
2011 Mukherjee S, Lin TY, Dowd KA, Manhart CJ, Pierson TC. The infectivity of prM-containing partially mature West Nile virus does not require the activity of cellular furin-like proteases. Journal of Virology. 85: 12067-72. PMID 21880759 DOI: 10.1128/Jvi.05559-11  0.76
2011 Dowd KA, Jost CA, Durbin AP, Whitehead SS, Pierson TC. A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus. Plos Pathogens. 7: e1002111. PMID 21738473 DOI: 10.1371/Journal.Ppat.1002111  0.76
2011 Ledgerwood JE, Pierson TC, Hubka SA, Desai N, Rucker S, Gordon IJ, Enama ME, Nelson S, Nason M, Gu W, Bundrant N, Koup RA, Bailer RT, Mascola JR, Nabel GJ, et al. A West Nile virus DNA vaccine utilizing a modified promoter induces neutralizing antibody in younger and older healthy adults in a phase I clinical trial. The Journal of Infectious Diseases. 203: 1396-404. PMID 21398392 DOI: 10.1093/Infdis/Jir054  0.76
2011 Dowd KA, Pierson TC. Antibody-mediated neutralization of flaviviruses: a reductionist view. Virology. 411: 306-15. PMID 21255816 DOI: 10.1016/J.Virol.2010.12.020  0.76
2010 Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin TY, Schneller S, Zust R, Dong H, Thiel V, Sen GC, Fensterl V, Klimstra WB, Pierson TC, et al. 2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature. 468: 452-6. PMID 21085181 DOI: 10.1038/Nature09489  0.72
2010 Fuchs A, Lin TY, Beasley DW, Stover CM, Schwaeble WJ, Pierson TC, Diamond MS. Direct complement restriction of flavivirus infection requires glycan recognition by mannose-binding lectin. Cell Host & Microbe. 8: 186-95. PMID 20709295 DOI: 10.1016/J.Chom.2010.07.007  0.68
2010 Sukupolvi-Petty S, Austin SK, Engle M, Brien JD, Dowd KA, Williams KL, Johnson S, Rico-Hesse R, Harris E, Pierson TC, Fremont DH, Diamond MS. Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2. Journal of Virology. 84: 9227-39. PMID 20592088 DOI: 10.1128/Jvi.01087-10  0.76
2010 Pierson TC. Modeling antibody-enhanced dengue virus infection and disease in mice: protection or pathogenesis? Cell Host & Microbe. 7: 85-6. PMID 20159612 DOI: 10.1016/j.chom.2010.02.004  0.76
2009 Mehlhop E, Nelson S, Jost CA, Gorlatov S, Johnson S, Fremont DH, Diamond MS, Pierson TC. Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus. Cell Host & Microbe. 6: 381-91. PMID 19837377 DOI: 10.1016/J.Chom.2009.09.003  0.76
2009 Nelson S, Poddar S, Lin TY, Pierson TC. Protonation of individual histidine residues is not required for the pH-dependent entry of west nile virus: evaluation of the "histidine switch" hypothesis. Journal of Virology. 83: 12631-5. PMID 19776132 DOI: 10.1128/Jvi.01072-09  0.76
2009 Sashihara J, Burbelo PD, Savoldo B, Pierson TC, Cohen JI. Human antibody titers to Epstein-Barr Virus (EBV) gp350 correlate with neutralization of infectivity better than antibody titers to EBV gp42 using a rapid flow cytometry-based EBV neutralization assay. Virology. 391: 249-56. PMID 19584018 DOI: 10.1016/J.Virol.2009.06.013  0.76
2009 Vogt MR, Moesker B, Goudsmit J, Jongeneelen M, Austin SK, Oliphant T, Nelson S, Pierson TC, Wilschut J, Throsby M, Diamond MS. Human monoclonal antibodies against West Nile virus induced by natural infection neutralize at a postattachment step. Journal of Virology. 83: 6494-507. PMID 19386704 DOI: 10.1128/Jvi.00286-09  0.76
2009 Mueller NH, Pattabiraman N, Ansarah-Sobrinho C, Viswanathan P, Pierson TC, Padmanabhan R. Identification and biochemical characterization of small-molecule inhibitors of West Nile virus serine protease by a high-throughput screen (Antimicrobial Agents and Chemotherapy (2008) 52, 9, (3385-3393)) Antimicrobial Agents and Chemotherapy. 53: 341. DOI: 10.1128/AAC.01525-08  0.76
2008 Pierson TC. Waste not, want not: a viral RNA degradation product modulates west nile virus pathogenesis. Cell Host & Microbe. 4: 512-3. PMID 19064251 DOI: 10.1016/j.chom.2008.11.004  0.76
2008 Diamond MS, Pierson TC, Fremont DH. The structural immunology of antibody protection against West Nile virus. Immunological Reviews. 225: 212-25. PMID 18837784 DOI: 10.1111/J.1600-065X.2008.00676.X  0.76
2008 Ansarah-Sobrinho C, Nelson S, Jost CA, Whitehead SS, Pierson TC. Temperature-dependent production of pseudoinfectious dengue reporter virus particles by complementation. Virology. 381: 67-74. PMID 18801552 DOI: 10.1016/J.Virol.2008.08.021  0.76
2008 Pierson TC, Fremont DH, Kuhn RJ, Diamond MS. Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development. Cell Host & Microbe. 4: 229-38. PMID 18779049 DOI: 10.1016/J.Chom.2008.08.004  0.76
2008 Mueller NH, Pattabiraman N, Ansarah-Sobrinho C, Viswanathan P, Pierson TC, Padmanabhan R. Identification and biochemical characterization of small-molecule inhibitors of west nile virus serine protease by a high-throughput screen. Antimicrobial Agents and Chemotherapy. 52: 3385-93. PMID 18606844 DOI: 10.1016/J.Antiviral.2007.01.016  0.76
2008 Pierson TC, Diamond MS. Molecular mechanisms of antibody-mediated neutralisation of flavivirus infection. Expert Reviews in Molecular Medicine. 10: e12. PMID 18471342 DOI: 10.1017/S1462399408000665  0.76
2008 Nelson S, Jost CA, Xu Q, Ess J, Martin JE, Oliphant T, Whitehead SS, Durbin AP, Graham BS, Diamond MS, Pierson TC. Maturation of West Nile virus modulates sensitivity to antibody-mediated neutralization. Plos Pathogens. 4: e1000060. PMID 18464894 DOI: 10.1371/Journal.Ppat.1000060  0.76
2008 Martin JE, Pierson TC, Graham BS. Reply to Rottinghaus and Poland Journal of Infectious Diseases. 197: 1628-1629. DOI: 10.1086/587945  0.76
2007 Martin JE, Pierson TC, Hubka S, Rucker S, Gordon IJ, Enama ME, Andrews CA, Xu Q, Davis BS, Nason M, Fay M, Koup RA, Roederer M, Bailer RT, Gomez PL, et al. A West Nile virus DNA vaccine induces neutralizing antibody in healthy adults during a phase 1 clinical trial. The Journal of Infectious Diseases. 196: 1732-40. PMID 18190252 DOI: 10.1086/523650  0.76
2007 Mehlhop E, Ansarah-Sobrinho C, Johnson S, Engle M, Fremont DH, Pierson TC, Diamond MS. Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specific manner. Cell Host & Microbe. 2: 417-26. PMID 18078693 DOI: 10.1016/J.Chom.2007.09.015  0.76
2007 Pierson TC, Xu Q, Nelson S, Oliphant T, Nybakken GE, Fremont DH, Diamond MS. The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection. Cell Host & Microbe. 1: 135-45. PMID 18005691 DOI: 10.1016/J.Chom.2007.03.002  0.76
2007 Oliphant T, Nybakken GE, Austin SK, Xu Q, Bramson J, Loeb M, Throsby M, Fremont DH, Pierson TC, Diamond MS. Induction of epitope-specific neutralizing antibodies against West Nile virus. Journal of Virology. 81: 11828-39. PMID 17715236 DOI: 10.1128/Jvi.00643-07  0.76
2007 Sánchez MD, Pierson TC, Degrace MM, Mattei LM, Hanna SL, Del Piero F, Doms RW. The neutralizing antibody response against West Nile virus in naturally infected horses. Virology. 359: 336-48. PMID 17055550 DOI: 10.1016/J.Virol.2006.08.047  0.76
2006 Oliphant T, Nybakken GE, Engle M, Xu Q, Nelson CA, Sukupolvi-Petty S, Marri A, Lachmi BE, Olshevsky U, Fremont DH, Pierson TC, Diamond MS. Antibody recognition and neutralization determinants on domains I and II of West Nile Virus envelope protein. Journal of Virology. 80: 12149-59. PMID 17035317 DOI: 10.1128/Jvi.01732-06  0.76
2006 Davis CW, Mattei LM, Nguyen HY, Ansarah-Sobrinho C, Doms RW, Pierson TC. The location of asparagine-linked glycans on West Nile virions controls their interactions with CD209 (dendritic cell-specific ICAM-3 grabbing nonintegrin). The Journal of Biological Chemistry. 281: 37183-94. PMID 17001080 DOI: 10.1074/Jbc.M605429200  0.76
2006 Davis CW, Nguyen HY, Hanna SL, Sánchez MD, Doms RW, Pierson TC. West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection. Journal of Virology. 80: 1290-301. PMID 16415006 DOI: 10.1128/Jvi.80.3.1290-1301.2006  0.76
2006 Pierson TC, Sánchez MD, Puffer BA, Ahmed AA, Geiss BJ, Valentine LE, Altamura LA, Diamond MS, Doms RW. A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection. Virology. 346: 53-65. PMID 16325883 DOI: 10.1016/J.Virol.2005.10.030  0.76
2006 Holden KL, Stein DA, Pierson TC, Ahmed AA, Clyde K, Iversen PL, Harris E. Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure. Virology. 344: 439-52. PMID 16214197 DOI: 10.1016/J.Virol.2005.08.034  0.76
2005 Hanna SL, Pierson TC, Sanchez MD, Ahmed AA, Murtadha MM, Doms RW. N-linked glycosylation of west nile virus envelope proteins influences particle assembly and infectivity. Journal of Virology. 79: 13262-74. PMID 16227249 DOI: 10.1128/Jvi.79.21.13262-13274.2005  0.76
2005 Whitby K, Pierson TC, Geiss B, Lane K, Engle M, Zhou Y, Doms RW, Diamond MS. Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. Journal of Virology. 79: 8698-706. PMID 15994763 DOI: 10.1128/Jvi.79.14.8698-8706.2005  0.76
2005 Geiss BJ, Pierson TC, Diamond MS. Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA. Virology Journal. 2: 53. PMID 15985182 DOI: 10.1186/1743-422X-2-53  0.76
2005 Sánchez MD, Pierson TC, McAllister D, Hanna SL, Puffer BA, Valentine LE, Murtadha MM, Hoxie JA, Doms RW. Characterization of neutralizing antibodies to West Nile virus. Virology. 336: 70-82. PMID 15866072 DOI: 10.1016/J.Virol.2005.02.020  0.76
2005 Pierson TC, Diamond MS, Ahmed AA, Valentine LE, Davis CW, Samuel MA, Hanna SL, Puffer BA, Doms RW. An infectious West Nile virus that expresses a GFP reporter gene. Virology. 334: 28-40. PMID 15749120 DOI: 10.1016/J.Virol.2005.01.021  0.76
2004 Puffer BA, Altamura LA, Pierson TC, Doms RW. Determinants within gp120 and gp41 contribute to CD4 independence of SIV Envs. Virology. 327: 16-25. PMID 15327894 DOI: 10.1016/J.Virol.2004.03.016  0.76
2004 Pierson TC, Doms RW, Pöhlmann S. Prospects of HIV-1 entry inhibitors as novel therapeutics. Reviews in Medical Virology. 14: 255-70. PMID 15248253 DOI: 10.1002/Rmv.435  0.76
2004 Han Y, Lassen K, Monie D, Sedaghat AR, Shimoji S, Liu X, Pierson TC, Margolick JB, Siliciano RF, Siliciano JD. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. Journal of Virology. 78: 6122-33. PMID 15163705 DOI: 10.1128/Jvi.78.12.6122-6133.2004  0.76
2004 Reeves JD, Miamidian JL, Biscone MJ, Lee FH, Ahmad N, Pierson TC, Doms RW. Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity. Journal of Virology. 78: 5476-85. PMID 15113926 DOI: 10.1128/Jvi.78.10.5476-5485.2004  0.76
2004 Crystal AS, Morais VA, Fortna RR, Carlin D, Pierson TC, Wilson CA, Lee VM, Doms RW. Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation. Biochemistry. 43: 3555-63. PMID 15035625 DOI: 10.1021/Bi0361214  0.76
2003 Pierson TC, Doms RW. HIV-1 entry and its inhibition. Current Topics in Microbiology and Immunology. 281: 1-27. PMID 12932074 DOI: 10.1007/978-3-642-19012-4_1  0.76
2003 Crystal AS, Morais VA, Pierson TC, Pijak DS, Carlin D, Lee VM, Doms RW. Membrane topology of gamma-secretase component PEN-2. The Journal of Biological Chemistry. 278: 20117-23. PMID 12639958 DOI: 10.1074/Jbc.M213107200  0.76
2003 Pierson TC, Doms RW. HIV-1 entry inhibitors: new targets, novel therapies. Immunology Letters. 85: 113-8. PMID 12527216 DOI: 10.1016/S0165-2478(02)00235-3  0.76
2002 Biscone MJ, Pierson TC, Doms RW. Opportunities and challenges in targeting HIV entry. Current Opinion in Pharmacology. 2: 529-33. PMID 12324254 DOI: 10.1016/S1471-4892(02)00200-X  0.76
2002 Pierson TC, Zhou Y, Kieffer TL, Ruff CT, Buck C, Siliciano RF. Molecular characterization of preintegration latency in human immunodeficiency virus type 1 infection. Journal of Virology. 76: 8518-31. PMID 12163571 DOI: 10.1128/Jvi.76.17.8518-8513.2002  0.76
2002 Pierson TC, Kieffer TL, Ruff CT, Buck C, Gange SJ, Siliciano RF. Intrinsic stability of episomal circles formed during human immunodeficiency virus type 1 replication. Journal of Virology. 76: 4138-44. PMID 11907256 DOI: 10.1128/Jvi.76.8.4138-4144.2002  0.76
2001 Buck CB, Shen X, Egan MA, Pierson TC, Walker CM, Siliciano RF. The human immunodeficiency virus type 1 gag gene encodes an internal ribosome entry site. Journal of Virology. 75: 181-91. PMID 11119587 DOI: 10.1128/Jvi.75.1.181-191.2001  0.76
2000 Shen A, Siliciano JD, Pierson TC, Buck CB, Siliciano RF. Establishment of latent HIV-1 infection of resting CD4(+) T lymphocytes does not require inactivation of Vpr. Virology. 278: 227-33. PMID 11112497 DOI: 10.1006/Viro.2000.0650  0.76
2000 Blankson JN, Finzi D, Pierson TC, Sabundayo BP, Chadwick K, Margolick JB, Quinn TC, Siliciano RF. Biphasic decay of latently infected CD4+ T cells in acute human immunodeficiency virus type 1 infection. The Journal of Infectious Diseases. 182: 1636-42. PMID 11069234 DOI: 10.1086/317615  0.76
2000 Pierson T, Hoffman TL, Blankson J, Finzi D, Chadwick K, Margolick JB, Buck C, Siliciano JD, Doms RW, Siliciano RF. Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1. Journal of Virology. 74: 7824-33. PMID 10933689 DOI: 10.1128/Jvi.74.17.7824-7833.2000  0.76
2000 Pierson T, McArthur J, Siliciano RF. Reservoirs for HIV-1: Mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy Annual Review of Immunology. 18: 665-708. PMID 10837072 DOI: 10.1146/Annurev.Immunol.18.1.665  0.76
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