Lin Shen, Ph.D. - Publications

2010 Johns Hopkins University, Baltimore, MD 
Pharmacology, Virology Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wang Y, Chen H, Jiao X, Wu L, Yang Y, Zhang J, Wu L, Liu C, Zhuo N, Li S, Gong J, Li J, Zhang X, Wang X, Peng Z, ... ... Shen L, et al. PTCH1 mutation promotes antitumor immunity and the response to immune checkpoint inhibitors in colorectal cancer patients. Cancer Immunology, Immunotherapy : Cii. PMID 34028566 DOI: 10.1007/s00262-021-02966-9  0.36
2021 Jiao X, Wei X, Li S, Liu C, Chen H, Gong J, Li J, Zhang X, Wang X, Peng Z, Qi C, Wang Z, Wang Y, Wang Y, Zhuo N, ... ... Shen L, et al. A genomic mutation signature predicts the clinical outcomes of immunotherapy and characterizes immunophenotypes in gastrointestinal cancer. Npj Precision Oncology. 5: 36. PMID 33947957 DOI: 10.1038/s41698-021-00172-5  0.36
2021 Qiu B, Zhao P, Shen L, Qiao S, Li G, Deng B, Zhou D, Wei Y. Improvement of Shen'ge formula on heart function in diastolic heart failure: A protocol for randomized, double-blind, placebo-controlled clinical study. Medicine. 100: e25383. PMID 33787645 DOI: 10.1097/MD.0000000000025383  0.36
2021 Liu D, Ma C, Lu P, Gong J, Ye D, Wang S, Peng P, Bai Y, Song Y, Chen J, Jiang O, Zhang G, Ba Y, Chen L, Pan J, ... ... Shen L, et al. Dose escalation and expansion (phase Ia/Ib) study of GLS-010, a recombinant fully human antiprogrammed death-1 monoclonal antibody for advanced solid tumors or lymphoma. European Journal of Cancer (Oxford, England : 1990). 148: 1-13. PMID 33691262 DOI: 10.1016/j.ejca.2021.01.020  0.36
2020 Zhang C, Chen Z, Chong X, Chen Y, Wang Z, Yu R, Sun T, Chen X, Shao Y, Zhang X, Gao J, Shen L. Clinical implications of plasma ctDNA features and dynamics in gastric cancer treated with HER2-targeted therapies. Clinical and Translational Medicine. 10: e254. PMID 33377634 DOI: 10.1002/ctm2.254  0.36
2020 Fan L, Chong X, Zhao M, Jia F, Wang Z, Zhou Y, Lu X, Huang Q, Li P, Yang Y, Hu Z, Li Q, Zhang X, Shen L. Ultrasensitive Gastric Cancer Circulating Tumor Cellular RNA Detection Based on a Molecular Beacon. Analytical Chemistry. PMID 33314914 DOI: 10.1021/acs.analchem.0c04055  0.36
2020 Wang Z, Zhao X, Gao C, Gong J, Wang X, Gao J, Li Z, Wang J, Yang B, Wang L, Zhang B, Zhou Y, Wang D, Li X, Bai Y, ... Shen L, et al. Plasma-based microsatellite instability detection strategy to guide immune checkpoint blockade treatment. Journal For Immunotherapy of Cancer. 8. PMID 33172882 DOI: 10.1136/jitc-2020-001297  0.36
2020 Lu Z, Chen H, Jiao X, Zhou W, Han W, Li S, Liu C, Gong J, Li J, Zhang X, Wang X, Peng Z, Qi C, Wang Z, Li Y, ... ... Shen L, et al. Prediction of immune checkpoint inhibition with immune oncology-related gene expression in gastrointestinal cancer using a machine learning classifier. Journal For Immunotherapy of Cancer. 8. PMID 32792359 DOI: 10.1136/jitc-2020-000631  0.36
2020 Lu Z, Chen H, Li S, Gong J, Li J, Zou J, Wu L, Yu J, Han W, Sun H, Jiao X, Zhang X, Peng Z, Lu M, Wang Z, ... ... Shen L, et al. Tumor copy-number alterations predict response to immune-checkpoint-blockade in gastrointestinal cancer. Journal For Immunotherapy of Cancer. 8. PMID 32792358 DOI: 10.1136/jitc-2019-000374  0.36
2020 Zhou Y, Zhang X, Wu X, Zhou Y, Zhang B, Liu X, Wu X, Li Y, Shen L, Li J. A prospective multicenter phase II study on the efficacy and safety of dasatinib in the treatment of metastatic gastrointestinal stromal tumors failed by imatinib and sunitinib and analysis of NGS in peripheral blood. Cancer Medicine. PMID 32677196 DOI: 10.1002/cam4.3319  0.36
2020 Huang P, Li R, Shen L, He W, Chen S, Dong Y, Ma J, Chen X, Xu M. Single nucleotide polymorphisms in telomere length-related genes are associated with hepatocellular carcinoma risk in the Chinese Han population. Therapeutic Advances in Medical Oncology. 12: 1758835920933029. PMID 32577134 DOI: 10.1177/1758835920933029  0.36
2020 Huang J, Xu J, Chen Y, Zhuang W, Zhang Y, Chen Z, Chen J, Zhang H, Niu Z, Fan Q, Lin L, Gu K, Liu Y, Ba Y, Miao Z, ... ... Shen L, et al. Camrelizumab versus investigator's choice of chemotherapy as second-line therapy for advanced or metastatic oesophageal squamous cell carcinoma (ESCORT): a multicentre, randomised, open-label, phase 3 study. The Lancet. Oncology. PMID 32416073 DOI: 10.1016/S1470-2045(20)30110-8  0.36
2020 Zhao S, Zhao H, Lv C, Gong J, Zhang J, Fang W, Li J, Hu X, Ba Y, Xu B, Zhang Y, Fan Y, Li K, Chen X, Yang Z, ... Shen L, et al. Anticancer drug R&D landscape in China. Journal of Hematology & Oncology. 13: 51. PMID 32404176 DOI: 10.1186/s13045-020-00877-3  0.36
2020 Wang X, Zhou J, Li Y, Ge Y, Zhou Y, Bai C, Shen L. Pharmacokinetics, Safety, and Preliminary Efficacy of Oral Trifluridine/Tipiracil in Chinese Patients with Solid Tumors: A Phase 1b, Open-Label Study. Clinical Pharmacology : Advances and Applications. 12: 21-33. PMID 32308505 DOI: 10.2147/CPAA.S232104  0.36
2020 Lu Z, Zou J, Li S, Topper MJ, Tao Y, Zhang H, Jiao X, Xie W, Kong X, Vaz M, Li H, Cai Y, Xia L, Huang P, Rodgers K, ... ... Shen L, et al. Epigenetic therapy inhibits metastases by disrupting premetastatic niches. Nature. PMID 32103175 DOI: 10.1038/S41586-020-2054-X  0.36
2019 Lu Z, Zou J, Hu Y, Li S, Zhou T, Gong J, Li J, Zhang X, Zhou J, Lu M, Wang X, Peng Z, Qi C, Li Y, Li J, ... ... Shen L, et al. Serological Markers Associated With Response to Immune Checkpoint Blockade in Metastatic Gastrointestinal Tract Cancer. Jama Network Open. 2: e197621. PMID 31339548 DOI: 10.1001/jamanetworkopen.2019.7621  0.36
2019 Wang M, Liang L, Lu J, Yu Y, Zhao Y, Shi Z, Li H, Xu X, Yan Y, Niu Y, Liu Z, Shen L, Zhang H. Delanzomib, a novel proteasome inhibitor, sensitizes breast cancer cells to doxorubicin-induced apoptosis. Thoracic Cancer. PMID 30883017 DOI: 10.1111/1759-7714.13030  0.36
2019 Zhou Y, Wang L, Zhang JR, Zhou K, Shuai J, Gong ZL, Liu Y, Wei F, Han YF, Shen L, Yang QW. Angioplasty and stenting for severe symptomatic atherosclerotic stenosis of intracranial vertebrobasilar artery. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 30850180 DOI: 10.1016/j.jocn.2019.02.017  0.36
2019 Zhao S, Lv C, Gong J, Wenfeng F, Hu X, Ba Y, Xiaoyuan C, Zhimin Y, Shen L, Zhang L. Challenges in anticancer drug R&D in China. The Lancet. Oncology. 20: 183-186. PMID 30723039 DOI: 10.1016/S1470-2045(18)30865-9  0.36
2019 Huang Y, Hong J, Liang C, Li G, Shen L, Zhang H, Hu X, Chen X. Nitrogen limitation affects the sinking property of Microcystis by promoting carbohydrate accumulation. Chemosphere. 221: 665-671. PMID 30677727 DOI: 10.1016/j.chemosphere.2019.01.080  0.36
2018 Zhang X, Zhou Y, Wu X, Nie M, Zhang B, Zhou Y, Sun L, Liu Z, Liu X, Kou Y, Wang Y, Zhang Y, Hao C, Shen L, Li J. Cytoreductive surgery for metastatic gastrointestinal stromal tumors followed by sunitinib compared to followed by imatinib-a multi-center cohort study. European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. PMID 30145000 DOI: 10.1016/j.ejso.2018.08.001  0.36
2018 Ge S, Xia X, Ding C, Zhen B, Zhou Q, Feng J, Yuan J, Chen R, Li Y, Ge Z, Ji J, Zhang L, Wang J, Li Z, Lai Y, ... ... Shen L, et al. Author Correction: A proteomic landscape of diffuse-type gastric cancer. Nature Communications. 9: 1850. PMID 29739932 DOI: 10.1038/S41467-018-04166-Z  0.36
2018 Shen L, Wu Y, Han L, Zhang H. Overexpression of growth and differentiation factor-5 inhibits inflammatory factors released by intervertebral disc cells. Experimental and Therapeutic Medicine. 15: 3603-3608. PMID 29545889 DOI: 10.3892/etm.2018.5867  0.36
2018 Ge S, Xia X, Ding C, Zhen B, Zhou Q, Feng J, Yuan J, Chen R, Li Y, Ge Z, Ji J, Zhang L, Wang J, Li Z, Lai Y, ... ... Shen L, et al. A proteomic landscape of diffuse-type gastric cancer. Nature Communications. 9: 1012. PMID 29520031 DOI: 10.1038/S41467-018-03121-2  0.36
2017 Li J, Cheng SY, Xiong XY, Duan CM, Liu L, Zhou Y, Zhang JR, Wang L, Zhou K, Gong ZL, Liu Y, Wei F, Shuai J, Shen L, Yang QW. Clinical significances and features of prompt brain CT scan after intracranial artery stenting: analysis of 501 cases. Oncotarget. 8: 114259-114267. PMID 29371984 DOI: 10.18632/oncotarget.23216  0.36
2017 Yang L, Shen L, Gao P, Li G, He Y, Wang M, Zhou H, Yuan H, Jin X, Wu X. Effect of AMPK signal pathway on pathogenesis of abdominal aortic aneurysms. Oncotarget. 8: 92827-92840. PMID 29190959 DOI: 10.18632/oncotarget.21608  0.36
2017 Li J, Ye Y, Wang J, Zhang B, Qin S, Shi Y, He Y, Liang X, Liu X, Zhou Y, Wu X, Zhang X, Wang M, Gao Z, Lin T, ... ... Shen L, et al. Chinese consensus guidelines for diagnosis and management of gastrointestinal stromal tumor. Chinese Journal of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu. 29: 281-293. PMID 28947860 DOI: 10.21147/j.issn.1000-9604.2017.04.01  0.36
2017 Guo L, Chen X, Yu B, Shen L, Zhang X. Delayed intracerebral hemorrhage secondary to ventriculoperitoneal shunt: a retrospective study. World Neurosurgery. PMID 28765020 DOI: 10.1016/j.wneu.2017.07.133  0.36
2017 Tang B, Wei M, Niu Q, Huang Y, Ru S, Liu X, Shen L, Fang Q. Antimicrobial Activity of Quinazolin Derivatives of 1,2-Di(quinazolin-4-yl)diselane against Mycobacteria. Biomed Research International. 2017: 5791781. PMID 28612027 DOI: 10.1155/2017/5791781  0.36
2016 Yang L, Shen L, Li G, Yuan H, Jin X, Wu X. Silencing of hypoxia inducible factor-1α gene attenuated angiotensin Ⅱ-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice. Atherosclerosis. 252: 40-49. PMID 27497884 DOI: 10.1016/j.atherosclerosis.2016.07.010  0.36
2015 Huang Y, Shen L, Cai A, Xiao J. Effect of warming Yang and removing blood stasis method on matrix metalloproteinases / tissue inhibitor metalloproteinases levels secreted by cultured endometrial cells from patients with endometriosis. Journal of Traditional Chinese Medicine = Chung I Tsa Chih Ying Wen Pan / Sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine. 35: 571-6. PMID 26591688  0.36
2015 Zhang J, Gao J, Li Y, Nie J, Dai L, Hu W, Chen X, Han J, Ma X, Tian G, Wu D, Shen L, Fang J. Circulating PD-L1 in NSCLC patients and the correlation between the level of PD-L1 expression and the clinical characteristics. Thoracic Cancer. 6: 534-8. PMID 26273411 DOI: 10.1111/1759-7714.12247  0.36
2015 Wu X, Liu R, Sathyamoorthy B, Yamato K, Liang G, Shen L, Ma S, Sukumaran DK, Szyperski T, Fang W, He L, Chen X, Gong B. Discrete stacking of aromatic oligoamide macrocycles. Journal of the American Chemical Society. 137: 5879-82. PMID 25909625 DOI: 10.1021/Jacs.5B02552  0.36
2015 Kang YK, Ryoo BY, Yoon S, Shen L, Lee J, Wei C, Zhou Y, Ryu MH. A Phase I study of cabazitaxel in patients with advanced gastric cancer who have failed prior chemotherapy (GASTANA). Cancer Chemotherapy and Pharmacology. 75: 309-18. PMID 25486878 DOI: 10.1007/s00280-014-2638-y  0.36
2015 Huang X, Qian Y, Wu H, Xie X, Zhou Q, Wang Y, Kuang W, Shen L, Li K, Su J, Shen L, Chen X. Aberrant expression of osteopontin and E-cadherin indicates radiation resistance and poor prognosis for patients with cervical carcinoma. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 63: 88-98. PMID 25380749 DOI: 10.1369/0022155414561329  0.36
2012 Jilek BL, Zarr M, Sampah ME, Rabi SA, Bullen CK, Lai J, Shen L, Siliciano RF. A quantitative basis for antiretroviral therapy for HIV-1 infection. Nature Medicine. 18: 446-51. PMID 22344296 DOI: 10.1038/Nm.2649  1
2012 Sampah ME, Jilek B, Shen L, Rabi A, Zarr M, Bullen CK, Lai J, Siliciano R. Quantifying combination ARV drug effects in wild type and resistant HIV-1 infection F1000research. 3. DOI: 10.7490/F1000Research.1089961.1  0.6
2011 Shen L, Rabi SA, Sedaghat AR, Shan L, Lai J, Xing S, Siliciano RF. A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs. Science Translational Medicine. 3: 91ra63. PMID 21753122 DOI: 10.1126/Scitranslmed.3002304  1
2011 Sampah ME, Shen L, Jilek BL, Siliciano RF. Dose-response curve slope is a missing dimension in the analysis of HIV-1 drug resistance. Proceedings of the National Academy of Sciences of the United States of America. 108: 7613-8. PMID 21502494 DOI: 10.1073/Pnas.1018360108  1
2011 McMahon MA, Parsons TL, Shen L, Siliciano JD, Siliciano RF. Consistent inhibition of HIV-1 replication in CD4+ T cells by acyclovir without detection of human herpesviruses. Journal of Virology. 85: 4618-22. PMID 21325417 DOI: 10.1128/Jvi.02423-10  1
2011 Rabi SA, O'Connell KA, Nikolaeva D, Bailey JR, Jilek BL, Shen L, Page KR, Siliciano RF, Blankson JN. Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection. Journal of Virology. 85: 979-86. PMID 21068257 DOI: 10.1128/Jvi.01721-10  1
2010 Bellows ML, Taylor MS, Cole PA, Shen L, Siliciano RF, Fung HK, Floudas CA. Discovery of entry inhibitors for HIV-1 via a new de novo protein design framework. Biophysical Journal. 99: 3445-53. PMID 21081094 DOI: 10.1016/J.Bpj.2010.09.050  1
2010 Shen L, Siliciano RF. Achieving a quantitative understanding of antiretroviral drug efficacy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 51: 1105-6; author reply. PMID 20925507 DOI: 10.1086/656688  1
2009 McMahon MA, Shen L, Siliciano RF. New approaches for quantitating the inhibition of HIV-1 replication by antiviral drugs in vitro and in vivo. Current Opinion in Infectious Diseases. 22: 574-82. PMID 19841584 DOI: 10.1097/Qco.0B013E328332C54D  0.88
2009 Shen L, Rabi SA, Siliciano RF. A novel method for determining the inhibitory potential of anti-HIV drugs. Trends in Pharmacological Sciences. 30: 610-6. PMID 19837466 DOI: 10.1016/J.Tips.2009.09.003  1
2009 Yang HC, Shen L, Siliciano RF, Pomerantz JL. Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 6321-6. PMID 19336585 DOI: 10.1073/Pnas.0809536106  1
2008 Shen L, Siliciano RF. Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection. The Journal of Allergy and Clinical Immunology. 122: 22-8. PMID 18602567 DOI: 10.1016/J.Jaci.2008.05.033  1
2008 Zhou Y, Shen L, Yang HC, Siliciano RF. Preferential cytolysis of peripheral memory CD4+ T cells by in vitro X4-tropic human immunodeficiency virus type 1 infection before the completion of reverse transcription. Journal of Virology. 82: 9154-63. PMID 18596085 DOI: 10.1128/Jvi.00773-08  1
2008 Shen L, Peterson S, Sedaghat AR, McMahon MA, Callender M, Zhang H, Zhou Y, Pitt E, Anderson KS, Acosta EP, Siliciano RF. Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs. Nature Medicine. 14: 762-6. PMID 18552857 DOI: 10.1038/Nm1777  1
2008 Sedaghat AR, Dinoso JB, Shen L, Wilke CO, Siliciano RF. Decay dynamics of HIV-1 depend on the inhibited stages of the viral life cycle. Proceedings of the National Academy of Sciences of the United States of America. 105: 4832-7. PMID 18362342 DOI: 10.1073/Pnas.0711372105  0.88
2007 McMahon MA, Jilek BL, Brennan TP, Shen L, Zhou Y, Wind-Rotolo M, Xing S, Bhat S, Hale B, Hegarty R, Chong CR, Liu JO, Siliciano RF, Thio CL. The HBV drug entecavir - effects on HIV-1 replication and resistance. The New England Journal of Medicine. 356: 2614-21. PMID 17582071 DOI: 10.1056/Nejmoa067710  1
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