Melanie D. Ohi, Ph.D. - Publications

Affiliations: 
2002 Vanderbilt University, Nashville, TN 
Area:
Cell Biology, Molecular Biology

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Caso GC, McClain MS, Erwin AL, Truelock MD, Campbell AM, Leasure CS, Nagel M, Schey KL, Lacy DB, Ohi MD, Cover TL. Functional properties of oligomeric and monomeric forms of VacA toxin. Infection and Immunity. IAI0034821. PMID 34543122 DOI: 10.1128/IAI.00348-21  1
2021 Sheedlo MJ, Durie CL, Chung JM, Chang L, Roberts J, Swanson M, Lacy DB, Ohi MD. Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife. 10. PMID 34519271 DOI: 10.7554/eLife.70427  1
2021 Fantin SM, Parson KF, Yadav P, Juliano B, Li GC, Sanders CR, Ohi MD, Ruotolo BT. Ion mobility-mass spectrometry reveals the role of peripheral myelin protein dimers in peripheral neuropathy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33893233 DOI: 10.1073/pnas.2015331118  1
2021 McIlwain BC, Erwin AL, Davis AR, Ben Koff B, Chang L, Bylund T, Chuang GY, Kwong PD, Ohi MD, Lai YT, Stockbridge RB. N-terminal transmembrane-helix epitope tag for x-ray crystallography and electron microscopy of small membrane proteins. Journal of Molecular Biology. 166909. PMID 33676924 DOI: 10.1016/j.jmb.2021.166909  0.01
2020 Snider CE, Chandra M, McDonald NA, Willet AH, Collier SE, Ohi MD, Jackson LP, Gould KL. Opposite Surfaces of the Cdc15 F-BAR Domain Create a Membrane Platform That Coordinates Cytoskeletal and Signaling Components for Cytokinesis. Cell Reports. 33: 108526. PMID 33357436 DOI: 10.1016/j.celrep.2020.108526  1
2020 Williamson LE, Gilliland T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, ... Ohi MD, et al. Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection. Cell. PMID 33301709 DOI: 10.1016/j.cell.2020.11.011  1
2020 Han B, Porta JC, Hanks JL, Peskova Y, Binshtein E, Dryden K, Claxton DP, Mchaourab HS, Karakas E, Ohi MD, Kenworthy AK. Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy. Science Advances. 6. PMID 33268374 DOI: 10.1126/sciadv.abc6185  1
2020 Sheedlo MJ, Chung JM, Sawhney N, Durie CL, Cover TL, Ohi MD, Lacy DB. Cryo-EM reveals species-specific components within the Cag type IV secretion system core complex. Elife. 9. PMID 32876048 DOI: 10.7554/Elife.59495  1
2020 Durie CL, Sheedlo MJ, Chung JM, Byrne BG, Su M, Knight T, Swanson M, Lacy DB, Ohi MD. Structural analysis of the Dot/Icm Type IV Secretion System Core Complex. Elife. 9. PMID 32876045 DOI: 10.7554/Elife.59530  1
2020 Cover TL, Lacy DB, Ohi MD. The Helicobacter pylori Cag Type IV Secretion System. Trends in Microbiology. PMID 32451226 DOI: 10.1016/J.Tim.2020.02.004  1
2020 Manthei KA, Patra D, Wilson CJ, Fawaz MV, Piersimoni L, Shenkar JC, Yuan W, Andrews PC, Engen JR, Schwendeman A, Ohi MD, Tesmer JJG. Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles. Communications Biology. 3: 28. PMID 31942029 DOI: 10.1038/s42003-019-0749-z  0.01
2020 Manthei K, Chang L, Tesmer J, Ohi M. CryoEM Analysis of Lecithin:Cholesterol Acyltransferase in Complex with High-Density Lipoprotein Particles Microscopy and Microanalysis. 1-3. DOI: 10.1017/S1431927620015147  0.01
2019 Takizawa Y, Ho CH, Tachiwana H, Matsunami H, Kobayashi W, Suzuki M, Arimura Y, Hori T, Fukagawa T, Ohi MD, Wolf M, Kurumizaka H. Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome. Structure (London, England : 1993). PMID 31711756 DOI: 10.1016/j.str.2019.10.016  1
2019 Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD. Structure of the Cag Type IV secretion system. Elife. 8. PMID 31210639 DOI: 10.7554/Elife.47644  1
2019 Ruetz M, Campanello GC, McDevitt L, Yokom AL, Yadav PK, Watkins D, Rosenblatt DS, Ohi MD, Southworth DR, Banerjee R. Allosteric Regulation of Oligomerization by a B Trafficking G-Protein Is Corrupted in Methylmalonic Aciduria. Cell Chemical Biology. PMID 31056463 DOI: 10.1016/J.Chembiol.2019.03.014  0.01
2019 Su M, Erwin AL, Campbell AM, Pyburn TM, Salay LE, Hanks JL, Lacy DB, Akey DL, Cover TL, Ohi MD. Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization. Journal of Molecular Biology. PMID 30954575 DOI: 10.1016/J.Jmb.2019.03.029  1
2019 Foegeding NJ, Raghunathan K, Campbell AM, Kim SW, Lau KS, Kenworthy AK, Cover TL, Ohi MD. Intracellular degradation of VacA toxin as a determinant of gastric epithelial cell viability. Infection and Immunity. PMID 30692181 DOI: 10.1128/Iai.00783-18  1
2019 Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD. Author response: Structure of the Helicobacter pylori Cag type IV secretion system Elife. DOI: 10.7554/Elife.47644.043  1
2018 Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, ... ... Ohi MD, et al. Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. PMID 30029854 DOI: 10.1016/J.Immuni.2018.06.018  1
2018 Norris SR, Jung S, Singh P, Strothman CE, Erwin AL, Ohi MD, Zanic M, Ohi R. Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters. Nature Communications. 9: 2659. PMID 29985404 DOI: 10.1038/S41467-018-04991-2  1
2018 Raghunathan K, Foegeding NJ, Campbell AM, Cover TL, Ohi MD, Kenworthy AK. Determinants of raft partitioning of thepore-forming toxin VacA. Infection and Immunity. PMID 29531133 DOI: 10.1128/Iai.00872-17  1
2018 Mousa JJ, Binshtein E, Human S, Fong RH, Alvarado G, Doranz BJ, Moore ML, Ohi MD, Crowe JE. Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins. Plos Pathogens. 14: e1006837. PMID 29470533 DOI: 10.1371/Journal.Ppat.1006837  1
2017 Chen Q, Perry NA, Vishnivetskiy SA, Berndt S, Gilbert NC, Zhuo Y, Singh PK, Tholen J, Ohi MD, Gurevich EV, Brautigam CA, Klug CS, Gurevich VV, Iverson TM. Structural basis of arrestin-3 activation and signaling. Nature Communications. 8: 1427. PMID 29127291 DOI: 10.1038/S41467-017-01218-8  0.01
2017 Ohi MD. Structural and functional analyses of the spliceosome requires a multi-disciplinary approach. Methods (San Diego, Calif.). 125: 1-2. PMID 28780959 DOI: 10.1016/J.Ymeth.2017.07.022  0.01
2017 Kroh HK, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi MD, Nyborg AC, Rainey GJ, Warrener P, Spiller BW, Lacy DB. Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. The Journal of Biological Chemistry. PMID 28705932 DOI: 10.1074/Jbc.M117.781112  1
2017 Mittendorf KF, Marinko JT, Hampton CM, Ke Z, Hadziselimovic A, Schlebach JP, Law CL, Li J, Wright ER, Sanders CR, Ohi MD. Peripheral myelin protein 22 alters membrane architecture. Science Advances. 3: e1700220. PMID 28695207 DOI: 10.1126/Sciadv.1700220  1
2017 Hernandez LD, Kroh HK, Hsieh E, Yang X, Beaumont M, Sheth PR, DiNunzio E, Rutherford SA, Ohi MD, Ermakov G, Xiao L, Secore S, Karczewski J, Racine F, Mayhood T, et al. Epitopes and Mechanism of Action of the Clostridium Difficile Toxin A-Neutralizing Antibody Actoxumab. Journal of Molecular Biology. PMID 28232034 DOI: 10.1016/J.Jmb.2017.02.010  1
2016 Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, ... Ohi MD, et al. Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791117 DOI: 10.1073/Pnas.1609449113  0.01
2016 Takizawa Y, Binshtein E, Erwin AL, Pyburn TM, Mittendorf KF, Ohi MD. While the Revolution Will Not Be Crystallized, Biochemistry Reigns Supreme. Protein Science : a Publication of the Protein Society. PMID 27673321 DOI: 10.1002/Pro.3054  1
2016 González-Rivera C, Campbell AM, Rutherford SA, Pyburn TM, Foegeding NJ, Barke TL, Spiller BW, McClain MS, Ohi MD, Lacy DB, Cover TL. A non-oligomerizing mutant form of Helicobacter pylori VacA allows structural analysis of the p33 domain. Infection and Immunity. PMID 27382020 DOI: 10.1128/Iai.00254-16  1
2016 Pyburn TM, Foegeding NJ, González-Rivera C, McDonald NA, Gould KL, Cover TL, Ohi MD. Structural organization of membrane-inserted hexamers formed by Helicobacter pylori VacA toxin. Molecular Microbiology. PMID 27309820 DOI: 10.1111/Mmi.13443  1
2016 Foegeding NJ, Caston RR, McClain MS, Ohi MD, Cover TL. An Overview of Helicobacter pylori VacA Toxin Biology. Toxins. 8. PMID 27271669 DOI: 10.3390/Toxins8060173  1
2016 McDonald NA, Takizawa Y, Feoktistova A, Xu P, Ohi MD, Vander Kooi CW, Gould KL. The Tubulation Activity of a Fission Yeast F-BAR Protein Is Dispensable for Its Function in Cytokinesis. Cell Reports. PMID 26776521 DOI: 10.1016/J.Celrep.2015.12.062  1
2016 Frick-Cheng AE, Pyburn TM, Voss BJ, McDonald WH, Ohi MD, Cover TL. Molecular and Structural Analysis of the Helicobacter pylori cag Type IV Secretion System Core Complex. Mbio. 7. PMID 26758182 DOI: 10.1128/Mbio.02001-15  1
2015 McDonald NA, Vander Kooi CW, Ohi MD, Gould KL. Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis. Developmental Cell. 35: 725-36. PMID 26702831 DOI: 10.1016/J.Devcel.2015.11.023  1
2015 Shin Y, Du Y, Collier SE, Ohi MD, Lang MJ, Ohi R. Biased Brownian motion as a mechanism to facilitate nanometer-scale exploration of the microtubule plus end by a kinesin-8. Proceedings of the National Academy of Sciences of the United States of America. 112: E3826-35. PMID 26150501 DOI: 10.1073/Pnas.1500272112  1
2015 Binshtein E, Ohi MD. Cryo-electron microscopy and the amazing race to atomic resolution. Biochemistry. 54: 3133-41. PMID 25955078 DOI: 10.1021/Acs.Biochem.5B00114  1
2015 Gao M, Thomson TC, Creed TM, Tu S, Loganathan SN, Jackson CA, McCluskey P, Lin Y, Collier SE, Weng Z, Lasko P, Ohi MD, Arkov AL. Glycolytic enzymes localize to ribonucleoprotein granules in Drosophila germ cells, bind Tudor and protect from transposable elements. Embo Reports. 16: 379-86. PMID 25600116 DOI: 10.15252/Embr.201439694  1
2015 Shin Y, Du Y, Collier SE, Ohi MD, Lang MJ, Ohi R. Biased Brownian motion as a mechanism to facilitate nanometer-scale exploration of the microtubule plus end by a kinesin-8 Proceedings of the National Academy of Sciences of the United States of America. 112: E3826-E3835. DOI: 10.1073/pnas.1500272112  1
2015 McDonald NA, Vander Kooi CW, Ohi MD, Gould KL. Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis Developmental Cell. 35: 725-736. DOI: 10.1016/j.devcel.2015.11.023  1
2014 Sturgill EG, Das DK, Takizawa Y, Shin Y, Collier SE, Ohi MD, Hwang W, Lang MJ, Ohi R. Kinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanism. Current Biology : Cb. 24: 2307-13. PMID 25264249 DOI: 10.1016/J.Cub.2014.08.022  1
2014 Collier SE, Voehler M, Peng D, Ohi R, Gould KL, Reiter NJ, Ohi MD. Structural and functional insights into the N-terminus of Schizosaccharomyces pombe Cdc5. Biochemistry. 53: 6439-51. PMID 25263959 DOI: 10.1021/Bi5008639  1
2013 Folkmann AW, Collier SE, Zhan X, Aditi, Ohi MD, Wente SR. Gle1 functions during mRNA export in an oligomeric complex that is altered in human disease. Cell. 155: 582-93. PMID 24243016 DOI: 10.1016/J.Cell.2013.09.023  1
2013 Livesay SB, Collier SE, Bitton DA, Bähler J, Ohi MD. Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Eukaryotic Cell. 12: 1472-89. PMID 24014766 DOI: 10.1128/Ec.00140-13  1
2013 Benefield DA, Dessain SK, Shine N, Ohi MD, Lacy DB. Molecular assembly of botulinum neurotoxin progenitor complexes. Proceedings of the National Academy of Sciences of the United States of America. 110: 5630-5. PMID 23509303 DOI: 10.1073/Pnas.1222139110  1
2013 Pattanayek R, Yadagiri KK, Ohi MD, Egli M. Nature of KaiB-KaiC binding in the cyanobacterial circadian oscillator. Cell Cycle (Georgetown, Tex.). 12: 810-7. PMID 23388462 DOI: 10.4161/Cc.23757  1
2013 Chambers MG, Pyburn TM, González-Rivera C, Collier SE, Eli I, Yip CK, Takizawa Y, Lacy DB, Cover TL, Ohi MD. Structural analysis of the oligomeric states of Helicobacter pylori VacA toxin. Journal of Molecular Biology. 425: 524-35. PMID 23178866 DOI: 10.1016/J.Jmb.2012.11.020  1
2012 Cox RG, Livesay SB, Johnson M, Ohi MD, Williams JV. The human metapneumovirus fusion protein mediates entry via an interaction with RGD-binding integrins. Journal of Virology. 86: 12148-60. PMID 22933271 DOI: 10.1128/Jvi.01133-12  1
2012 Mittendorf KF, Deatherage CL, Ohi MD, Sanders CR. Tailoring of membrane proteins by alternative splicing of pre-mRNA. Biochemistry. 51: 5541-56. PMID 22708632 DOI: 10.1021/Bi3007065  1
2012 Johnson AE, Collier SE, Ohi MD, Gould KL. Fission yeast Dma1 requires RING domain dimerization for its ubiquitin ligase activity and mitotic checkpoint function. The Journal of Biological Chemistry. 287: 25741-8. PMID 22669973 DOI: 10.1074/Jbc.M112.349712  1
2011 Chen JS, Lu LX, Ohi MD, Creamer KM, English C, Partridge JF, Ohi R, Gould KL. Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation. The Journal of Cell Biology. 195: 583-93. PMID 22065639 DOI: 10.1083/Jcb.201105074  1
2011 Archuleta TL, Du Y, English CA, Lory S, Lesser C, Ohi MD, Ohi R, Spiller BW. The Chlamydia effector chlamydial outer protein N (CopN) sequesters tubulin and prevents microtubule assembly. The Journal of Biological Chemistry. 286: 33992-8. PMID 21841198 DOI: 10.1074/Jbc.M111.258426  1
2011 Ren L, McLean JR, Hazbun TR, Fields S, Vander Kooi C, Ohi MD, Gould KL. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Plos One. 6: e16719. PMID 21386897 DOI: 10.1371/Journal.Pone.0016719  1
2011 McLean JR, Chaix D, Ohi MD, Gould KL. State of the APC/C: organization, function, and structure. Critical Reviews in Biochemistry and Molecular Biology. 46: 118-36. PMID 21261459 DOI: 10.3109/10409238.2010.541420  1
2010 Pruitt RN, Chambers MG, Ng KK, Ohi MD, Lacy DB. Structural organization of the functional domains of Clostridium difficile toxins A and B. Proceedings of the National Academy of Sciences of the United States of America. 107: 13467-72. PMID 20624955 DOI: 10.1073/Pnas.1002199107  1
2010 Roberts-Galbraith RH, Ohi MD, Ballif BA, Chen JS, McLeod I, McDonald WH, Gygi SP, Yates JR, Gould KL. Dephosphorylation of F-BAR Protein Cdc15 Modulates Its Conformation and Stimulates Its Scaffolding Activity at the Cell Division Site Molecular Cell. 39: 86-99. PMID 20603077 DOI: 10.1016/J.Molcel.2010.06.012  1
2010 González-Rivera C, Gangwer KA, McClain MS, Eli IM, Chambers MG, Ohi MD, Lacy DB, Cover TL. Reconstitution of Helicobacter pylori VacA toxin from purified components. Biochemistry. 49: 5743-52. PMID 20527875 DOI: 10.1021/Bi100618G  1
2010 Vander Kooi CW, Ren L, Xu P, Ohi MD, Gould KL, Chazin WJ. The Prp19 WD40 domain contains a conserved protein interaction region essential for its function Structure. 18: 584-593. PMID 20462492 DOI: 10.1016/J.Str.2010.02.015  1
2007 Ohi MD, Feoktistova A, Ren L, Yip C, Cheng Y, Chen JS, Yoon HJ, Wall JS, Huang Z, Penczek PA, Gould KL, Walz T. Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1. Molecular Cell. 28: 871-85. PMID 18082611 DOI: 10.1016/J.Molcel.2007.10.003  1
2007 Ohi MD, Ren L, Wall JS, Gould KL, Walz T. Structural characterization of the fission yeast U5.U2/U6 spliceosome complex. Proceedings of the National Academy of Sciences of the United States of America. 104: 3195-200. PMID 17360628 DOI: 10.1073/Pnas.0611591104  1
2007 Huang DT, Hunt HW, Zhuang M, Ohi MD, Holton JM, Schulman BA. Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity. Nature. 445: 394-8. PMID 17220875 DOI: 10.1038/Nature05490  1
2006 Crampton DJ, Ohi M, Qimron U, Walz T, Richardson CC. Oligomeric states of bacteriophage T7 gene 4 primase/helicase. Journal of Molecular Biology. 360: 667-77. PMID 16777142 DOI: 10.1016/J.Jmb.2006.05.037  1
2006 Vander Kooi CW, Ohi MD, Rosenberg JA, Oldham ML, Newcomer ME, Gould KL, Chazin WJ. The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases Biochemistry. 45: 121-130. PMID 16388587 DOI: 10.1021/Bi051787E  1
2006 Wilkinson CRM, Dittmar GAG, Ohi MD, Uetz P, Jones N, Finley D. Ubiquitin-like Protein Hub1 Is Required for pre-mRNA Splicing and Localization of an Essential Splicing Factor in Fission Yeast (DOI:10.1016/j.cub.2004.11.058) Current Biology. 16: 2488. DOI: 10.1016/J.Cub.2006.12.004  1
2005 Ohi MD, Vander Kooi CW, Rosenberg JA, Ren L, Hirsch JP, Chazin WJ, Walz T, Gould KL. Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Molecular and Cellular Biology. 25: 451-60. PMID 15601865 DOI: 10.1128/Mcb.25.1.451-460.2005  1
2004 Wilkinson CR, Dittmar GA, Ohi MD, Uetz P, Jones N, Finley D. Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast. Current Biology : Cb. 14: 2283-8. PMID 15620657 DOI: 10.1016/J.Cub.2004.11.058  1
2004 Ohi M, Li Y, Cheng Y, Walz T. Negative staining and image classification - Powerful tools in modern electron microscopy Biological Procedures Online. 6: 23-34. DOI: 10.1251/bpo70  1
2003 Ohi MD, Vander Kooi CW, Rosenberg JA, Chazin WJ, Gould KL. Structural insights into the U-box, a domain associated with multi-ubiquitination. Nature Structural Biology. 10: 250-5. PMID 12627222 DOI: 10.1038/Nsb906  1
2002 Ohi MD, Gould KL. Characterization of interactions among the Cef1p-Prp19p-associated splicing complex Rna. 8: 798-815. PMID 12088152 DOI: 10.1017/S1355838202025050  1
2002 Ohi MD, Link AJ, Ren L, Jennings JL, McDonald WH, Gould KL. Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Molecular and Cellular Biology. 22: 2011-24. PMID 11884590 DOI: 10.1128/Mcb.22.7.2011-2024.2002  1
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