Jennifer A. Mertz, Ph.D. - Publications

Affiliations: 
2003 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Molecular Biology, Cell Biology

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Albrecht BK, Gehling VS, Hewitt MC, Vaswani RG, Cote A, Leblanc Y, Nasveschuk CG, Bellon S, Bergeron L, Campbell R, Cantone N, Cooper MR, Cummings RT, Jayaram H, Joshi S, ... Mertz JA, et al. Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials. Journal of Medicinal Chemistry. PMID 26815195 DOI: 10.1021/acs.jmedchem.5b01882  0.76
2016 Conery AR, Centore RC, Spillane KL, Follmer NE, Bommi-Reddy A, Hatton C, Bryant BM, Greninger P, Amzallag A, Benes CH, Mertz JA, Sims RJ. Preclinical anticancer efficacy of BET bromodomain inhibitors is determined by the apoptotic response. Cancer Research. PMID 26759243 DOI: 10.1158/0008-5472.CAN-15-1458  0.76
2016 Conery AR, Centore RC, Neiss A, Keller PJ, Joshi S, Spillane KL, Sandy P, Hatton C, Pardo E, Zawadzke L, Bommi-Reddy A, Gascoigne KE, Bryant BM, Mertz JA, Sims RJ. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. Elife. 5. PMID 26731516 DOI: 10.7554/eLife.10483  0.76
2015 Hewitt MC, Leblanc Y, Gehling VS, Vaswani RG, Côté A, Nasveschuk CG, Taylor AM, Harmange JC, Audia JE, Pardo E, Cummings R, Joshi S, Sandy P, Mertz JA, Sims RJ, et al. Development of methyl isoxazoleazepines as inhibitors of BET. Bioorganic & Medicinal Chemistry Letters. 25: 1842-8. PMID 25851940 DOI: 10.1016/j.bmcl.2015.03.045  0.76
2013 Gehling VS, Hewitt MC, Vaswani RG, Leblanc Y, Côté A, Nasveschuk CG, Taylor AM, Harmange JC, Audia JE, Pardo E, Joshi S, Sandy P, Mertz JA, Sims RJ, Bergeron L, et al. Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors. Acs Medicinal Chemistry Letters. 4: 835-40. PMID 24900758 DOI: 10.1021/ml4001485  0.76
2011 Mertz JA, Conery AR, Bryant BM, Sandy P, Balasubramanian S, Mele DA, Bergeron L, Sims RJ. Targeting MYC dependence in cancer by inhibiting BET bromodomains. Proceedings of the National Academy of Sciences of the United States of America. 108: 16669-74. PMID 21949397 DOI: 10.1073/pnas.1108190108  0.76
2010 Byun H, Halani N, Mertz JA, Ali AF, Lozano MM, Dudley JP. Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function. Proceedings of the National Academy of Sciences of the United States of America. 107: 12287-92. PMID 20566871 DOI: 10.1073/pnas.1004303107  0.76
2009 Mertz JA, Chadee AB, Byun H, Russell R, Dudley JP. Mapping of the functional boundaries and secondary structure of the mouse mammary tumor virus Rem-responsive element. The Journal of Biological Chemistry. 284: 25642-52. PMID 19632991 DOI: 10.1074/jbc.M109.012476  0.76
2009 Mertz JA, Lozano MM, Dudley JP. Rev and Rex proteins of human complex retroviruses function with the MMTV Rem-responsive element. Retrovirology. 6: 10. PMID 19192308 DOI: 10.1186/1742-4690-6-10  0.76
2007 Mertz JA, Kobayashi R, Dudley JP. ALY is a common coactivator of RUNX1 and c-Myb on the type B leukemogenic virus enhancer. Journal of Virology. 81: 3503-13. PMID 17229714 DOI: 10.1128/JVI.02253-06  0.76
2005 Mertz JA, Simper MS, Lozano MM, Payne SM, Dudley JP. Mouse mammary tumor virus encodes a self-regulatory RNA export protein and is a complex retrovirus. Journal of Virology. 79: 14737-47. PMID 16282474 DOI: 10.1128/JVI.79.23.14737-14747.2005  0.76
2002 Dudley JP, Mertz JA, Rajan L, Lozano M, Broussard DR. What retroviruses teach us about the involvement of c-Myc in leukemias and lymphomas. Leukemia. 16: 1086-98. PMID 12040439 DOI: 10.1038/sj.leu.2402451  0.76
2002 Broussard DR, Mertz JA, Lozano M, Dudley JP. Selection for c-myc integration sites in polyclonal T-cell lymphomas. Journal of Virology. 76: 2087-99. PMID 11836386 DOI: 10.1128/jvi.76.5.2087-2099.2002  0.76
2001 Mertz JA, Mustafa F, Meyers S, Dudley JP. Type B leukemogenic virus has a T-cell-specific enhancer that binds AML-1. Journal of Virology. 75: 2174-84. PMID 11160721 DOI: 10.1128/JVI.75.5.2174-2184.2001  0.76
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