Chad A. Rappleye, Ph.D. - Publications

2002 University of California, San Diego, La Jolla, CA 
Cell Biology, Animal Physiology Biology

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Xiao Y, Tang J, Guo H, Zhao Y, Tang R, Ouyang S, Zeng Q, Rappleye CA, Rajaram MV, Schlesinger LS, Tao L, Brown GD, Langdon WY, Li BT, Zhang J. Targeting CBLB as a potential therapeutic approach for disseminated candidiasis. Nature Medicine. PMID 27428899 DOI: 10.1038/Nm.4141  0.96
2016 Garfoot AL, Shen Q, Wüthrich M, Klein BS, Rappleye CA. The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure. Mbio. 7. PMID 27094334 DOI: 10.1128/Mbio.01388-15  0.96
2016 Garfoot AL, Rappleye CA. Histoplasma capsulatum surmounts obstacles to intracellular pathogenesis. The Febs Journal. 283: 619-33. PMID 26235362 DOI: 10.1111/Febs.13389  0.96
2015 Goughenour KD, Balada-Llasat JM, Rappleye CA. Quantitative Microplate-Based Growth Assay for Determination of Antifungal Susceptibility of Histoplasma capsulatum Yeasts. Journal of Clinical Microbiology. 53: 3286-95. PMID 26246483 DOI: 10.1128/Jcm.00795-15  0.96
2015 Khalil A, Edwards JA, Rappleye CA, Tjarks W. Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans. Bioorganic & Medicinal Chemistry. 23: 532-47. PMID 25543205 DOI: 10.1016/J.Bmc.2014.12.006  0.96
2015 Oghumu S, Stock JC, Varikuti S, Dong R, Terrazas C, Edwards JA, Rappleye CA, Holovatyk A, Sharpe A, Satoskar AR. Transgenic expression of CXCR3 on T cells enhances susceptibility to cutaneous Leishmania major infection by inhibiting monocyte maturation and promoting a Th2 response. Infection and Immunity. 83: 67-76. PMID 25312956 DOI: 10.1128/Iai.02540-14  0.96
2014 Holbrook ED, Kemski MM, Richer SM, Wheat LJ, Rappleye CA. Glycosylation and immunoreactivity of the Histoplasma capsulatum Cfp4 yeast-phase exoantigen. Infection and Immunity. 82: 4414-25. PMID 25114108 DOI: 10.1128/Iai.01893-14  0.96
2014 Garfoot AL, Zemska O, Rappleye CA. Histoplasma capsulatum depends on de novo vitamin biosynthesis for intraphagosomal proliferation. Infection and Immunity. 82: 393-404. PMID 24191299 DOI: 10.1128/Iai.00824-13  0.96
2013 Edwards JA, Chen C, Kemski MM, Hu J, Mitchell TK, Rappleye CA. Histoplasma yeast and mycelial transcriptomes reveal pathogenic-phase and lineage-specific gene expression profiles. Bmc Genomics. 14: 695. PMID 24112604 DOI: 10.1186/1471-2164-14-695  0.96
2013 Edwards JA, Kemski MM, Rappleye CA. Identification of an aminothiazole with antifungal activity against intracellular Histoplasma capsulatum. Antimicrobial Agents and Chemotherapy. 57: 4349-59. PMID 23817367 DOI: 10.1128/Aac.00459-13  0.96
2013 Holbrook ED, Smolnycki KA, Youseff BH, Rappleye CA. Redundant catalases detoxify phagocyte reactive oxygen and facilitate Histoplasma capsulatum pathogenesis. Infection and Immunity. 81: 2334-46. PMID 23589579 DOI: 10.1128/Iai.00173-13  0.96
2013 Kemski MM, Stevens B, Rappleye CA. Spectrum of T-DNA integrations for insertional mutagenesis of Histoplasma capsulatum. Fungal Biology. 117: 41-51. PMID 23332832 DOI: 10.1016/J.Funbio.2012.11.004  0.96
2012 Youseff BH, Holbrook ED, Smolnycki KA, Rappleye CA. Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress. Plos Pathogens. 8: e1002713. PMID 22615571 DOI: 10.1371/Journal.Ppat.1002713  0.96
2012 Youseff BH, Rappleye CA. RNAi-based gene silencing using a GFP sentinel system in Histoplasma capsulatum. Methods in Molecular Biology (Clifton, N.J.). 845: 151-64. PMID 22328373 DOI: 10.1007/978-1-61779-539-8_10  0.96
2012 Zemska O, Rappleye CA. Agrobacterium-mediated insertional mutagenesis in Histoplasma capsulatum. Methods in Molecular Biology (Clifton, N.J.). 845: 51-66. PMID 22328367 DOI: 10.1007/978-1-61779-539-8_4  0.96
2011 Edwards JA, Rappleye CA. Histoplasma mechanisms of pathogenesis--one portfolio doesn't fit all. Fems Microbiology Letters. 324: 1-9. PMID 22092757 DOI: 10.1111/J.1574-6968.2011.02363.X  0.96
2011 Edwards JA, Zemska O, Rappleye CA. Discovery of a role for Hsp82 in Histoplasma virulence through a quantitative screen for macrophage lethality. Infection and Immunity. 79: 3348-57. PMID 21606189 DOI: 10.1128/Iai.05124-11  0.96
2011 Holbrook ED, Edwards JA, Youseff BH, Rappleye CA. Definition of the extracellular proteome of pathogenic-phase Histoplasma capsulatum. Journal of Proteome Research. 10: 1929-43. PMID 21291285 DOI: 10.1021/Pr1011697  0.96
2011 Edwards JA, Alore EA, Rappleye CA. The yeast-phase virulence requirement for α-glucan synthase differs among Histoplasma capsulatum chemotypes. Eukaryotic Cell. 10: 87-97. PMID 21037179 DOI: 10.1128/Ec.00214-10  0.96
2009 Youseff BH, Dougherty JA, Rappleye CA. Reverse genetics through random mutagenesis in Histoplasma capsulatum. Bmc Microbiology. 9: 236. PMID 19919692 DOI: 10.1186/1471-2180-9-236  0.96
2008 Holbrook ED, Rappleye CA. Histoplasma capsulatum pathogenesis: making a lifestyle switch. Current Opinion in Microbiology. 11: 318-24. PMID 18573684 DOI: 10.1016/J.Mib.2008.05.010  0.96
2008 Rappleye CA, Goldman WE. Fungal stealth technology. Trends in Immunology. 29: 18-24. PMID 18054285 DOI: 10.1016/J.It.2007.10.001  0.96
2007 Almeida AJ, Carmona JA, Cunha C, Carvalho A, Rappleye CA, Goldman WE, Hooykaas PJ, Leão C, Ludovico P, Rodrigues F. Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis. Fungal Genetics and Biology : Fg & B. 44: 1387-98. PMID 17512227 DOI: 10.1016/J.Fgb.2007.04.004  0.96
2007 Krajaejun T, Gauthier GM, Rappleye CA, Sullivan TD, Klein BS. Development and application of a green fluorescent protein sentinel system for identification of RNA interference in Blastomyces dermatitidis illuminates the role of septin in morphogenesis and sporulation. Eukaryotic Cell. 6: 1299-309. PMID 17496124 DOI: 10.1128/Ec.00401-06  0.96
2007 Rappleye CA, Eissenberg LG, Goldman WE. Histoplasma capsulatum alpha-(1,3)-glucan blocks innate immune recognition by the beta-glucan receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 1366-70. PMID 17227865 DOI: 10.1073/Pnas.0609848104  0.96
2006 Marion CL, Rappleye CA, Engle JT, Goldman WE. An alpha-(1,4)-amylase is essential for alpha-(1,3)-glucan production and virulence in Histoplasma capsulatum. Molecular Microbiology. 62: 970-83. PMID 17038119 DOI: 10.1111/J.1365-2958.2006.05436.X  0.96
2006 Rappleye CA, Goldman WE. Defining virulence genes in the dimorphic fungi. Annual Review of Microbiology. 60: 281-303. PMID 16753032 DOI: 10.1146/Annurev.Micro.59.030804.121055  0.96
2004 Rappleye CA, Engle JT, Goldman WE. RNA interference in Histoplasma capsulatum demonstrates a role for alpha-(1,3)-glucan in virulence. Molecular Microbiology. 53: 153-65. PMID 15225311 DOI: 10.1111/J.1365-2958.2004.04131.X  0.96
2003 Rappleye CA, Tagawa A, Le Bot N, Ahringer J, Aroian RV. Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity. Bmc Developmental Biology. 3: 8. PMID 14527340 DOI: 10.1186/1471-213X-3-8  0.96
2002 Rappleye CA, Tagawa A, Lyczak R, Bowerman B, Aroian RV. The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Developmental Cell. 2: 195-206. PMID 11832245 DOI: 10.1016/S1534-5807(02)00114-4  0.96
2001 Tagawa A, Rappleye CA, Aroian RV. Pod-2, along with pod-1, defines a new class of genes required for polarity in the early Caenorhabditis elegans embryo. Developmental Biology. 233: 412-24. PMID 11336504 DOI: 10.1006/Dbio.2001.0234  0.96
1999 Rappleye CA, Paredez AR, Smith CW, McDonald KL, Aroian RV. The coronin-like protein POD-1 is required for anterior-posterior axis formation and cellular architecture in the nematode caenorhabditis elegans. Genes & Development. 13: 2838-51. PMID 10557211 DOI: 10.1101/Gad.13.21.2838  0.96
1999 Kofoid E, Rappleye C, Stojiljkovic I, Roth J. The 17-gene ethanolamine (eut) operon of Salmonella typhimurium encodes five homologues of carboxysome shell proteins Journal of Bacteriology. 181: 5317-5329. PMID 10464203 DOI: 10.1128/Jb.181.17.5317-5329.1999  0.96
1997 Rappleye CA, Roth JR. A Tn10 derivative (T-POP) for isolation of insertions with conditional (tetracycline-dependent) phenotypes Journal of Bacteriology. 179: 5827-5834. PMID 9294441 DOI: 10.1128/Jb.179.18.5827-5834.1997  0.96
1997 Rappleye CA, Roth JR. Transposition without transposase: A spontaneous mutation in bacteria Journal of Bacteriology. 179: 2047-2052. PMID 9068653 DOI: 10.1128/Jb.179.6.2047-2052.1997  0.96
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