Thomas J. Hannan, Ph.D. - Publications

Affiliations: 
2008 Washington University, Saint Louis, St. Louis, MO 
Area:
Microbiology Biology, Immunology, Pathology

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yu L, O'Brien VP, Livny J, Dorsey D, Bandyopadhyay N, Colonna M, Caparon MG, Roberson ED, Hultgren SJ, Hannan TJ. Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence. Elife. 8. PMID 31429405 DOI: 10.7554/eLife.46677  0.84
2018 O'Brien VP, Dorsey DA, Hannan TJ, Hultgren SJ. Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner. Plos Pathogens. 14: e1007457. PMID 30543708 DOI: 10.1371/journal.ppat.1007457  0.84
2017 Mydock-McGrane LK, Hannan TJ, Janetka JW. Rational Design Strategies for FimH Antagonists: New Drugs on the Horizon for Urinary Tract Infection and Crohn's Disease. Expert Opinion On Drug Discovery. PMID 28506090 DOI: 10.1080/17460441.2017.1331216  0.68
2017 Schreiber HL, Conover MS, Chou WC, Hibbing ME, Manson AL, Dodson KW, Hannan TJ, Roberts PL, Stapleton AE, Hooton TM, Livny J, Earl AM, Hultgren SJ. Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections. Science Translational Medicine. 9. PMID 28330863 DOI: 10.1126/scitranslmed.aaf1283  0.84
2017 Kalas V, Pinkner JS, Hannan TJ, Hibbing ME, Dodson KW, Holehouse AS, Zhang H, Tolia NH, Gross ML, Pappu RV, Janetka J, Hultgren SJ. Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions. Science Advances. 3: e1601944. PMID 28246638 DOI: 10.1126/sciadv.1601944  0.84
2016 O'Brien VP, Hannan TJ, Yu L, Livny J, Roberson ED, Schwartz DJ, Souza S, Mendelsohn CL, Colonna M, Lewis AL, Hultgren SJ. A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease. Nature Microbiology. 2: 16196. PMID 27798558 DOI: 10.1038/nmicrobiol.2016.196  0.84
2016 O'Brien VP, Hannan TJ, Nielsen HV, Hultgren SJ. Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections. Microbiology Spectrum. 4. PMID 26999391 DOI: 10.1128/microbiolspec.UTI-0013-2012  0.84
2016 Hannan TJ, Hunstad DA. A Murine Model for Escherichia coli Urinary Tract Infection. Methods in Molecular Biology (Clifton, N.J.). 1333: 159-75. PMID 26468108 DOI: 10.1007/978-1-4939-2854-5_14  0.68
2015 Lin AE, Beasley FC, Olson J, Keller N, Shalwitz RA, Hannan TJ, Hultgren SJ, Nizet V. Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection. Plos Pathogens. 11: e1004818. PMID 25927232 DOI: 10.1371/journal.ppat.1004818  0.68
2015 Goneau LW, Hannan TJ, MacPhee RA, Schwartz DJ, Macklaim JM, Gloor GB, Razvi H, Reid G, Hultgren SJ, Burton JP. Subinhibitory antibiotic therapy alters recurrent urinary tract infection pathogenesis through modulation of bacterial virulence and host immunity. Mbio. 6. PMID 25827417 DOI: 10.1128/mBio.00356-15  0.84
2015 Nagamatsu K, Hannan TJ, Guest RL, Kostakioti M, Hadjifrangiskou M, Binkley J, Dodson K, Raivio TL, Hultgren SJ. Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection. Proceedings of the National Academy of Sciences of the United States of America. 112: E871-80. PMID 25675528 DOI: 10.1073/pnas.1500374112  0.68
2015 Schwartz DJ, Conover MS, Hannan TJ, Hultgren SJ. Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection. Plos Pathogens. 11: e1004599. PMID 25569799 DOI: 10.1371/journal.ppat.1004599  0.84
2015 O'Brien VP, Hannan TJ, Schaeffer AJ, Hultgren SJ. Are you experienced? Understanding bladder innate immunity in the context of recurrent urinary tract infection. Current Opinion in Infectious Diseases. 28: 97-105. PMID 25517222 DOI: 10.1097/QCO.0000000000000130  0.68
2014 Hannan TJ, Roberts PL, Riehl TE, van der Post S, Binkley JM, Schwartz DJ, Miyoshi H, Mack M, Schwendener RA, Hooton TM, Stappenbeck TS, Hansson GC, Stenson WF, Colonna M, Stapleton AE, et al. Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis. Ebiomedicine. 1: 46-57. PMID 26125048 DOI: 10.1016/j.ebiom.2014.10.011  0.84
2013 Hannan TJ, Hooton TM, Hultgren SJ. Estrogen and recurrent UTI: what are the facts? Science Translational Medicine. 5: 190fs23. PMID 23785033 DOI: 10.1126/scitranslmed.3006423  0.68
2013 Totsika M, Kostakioti M, Hannan TJ, Upton M, Beatson SA, Janetka JW, Hultgren SJ, Schembri MA. A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. The Journal of Infectious Diseases. 208: 921-8. PMID 23737602 DOI: 10.1093/infdis/jit245  0.68
2013 Guiton PS, Hannan TJ, Ford B, Caparon MG, Hultgren SJ. Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections. Infection and Immunity. 81: 329-39. PMID 23132492 DOI: 10.1128/IAI.00856-12  0.68
2012 Kostakioti M, Hadjifrangiskou M, Cusumano CK, Hannan TJ, Janetka JW, Hultgren SJ. Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection Infection and Immunity. 80: 2826-2834. PMID 22665375 DOI: 10.1128/IAI.00283-12  0.68
2012 Hannan TJ, Totsika M, Mansfield KJ, Moore KH, Schembri MA, Hultgren SJ. Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. Fems Microbiology Reviews. 36: 616-48. PMID 22404313 DOI: 10.1111/j.1574-6976.2012.00339.x  0.68
2010 Hannan TJ, Mysorekar IU, Hung CS, Isaacson-Schmid ML, Hultgren SJ. Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. Plos Pathogens. 6: e1001042. PMID 20811584 DOI: 10.1371/journal.ppat.1001042  0.68
2008 Hannan TJ, Mysorekar IU, Chen SL, Walker JN, Jones JM, Pinkner JS, Hultgren SJ, Seed PC. LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis. Molecular Microbiology. 67: 116-28. PMID 18036139 DOI: 10.1111/j.1365-2958.2007.06025.x  0.68
2006 Remaut H, Rose RJ, Hannan TJ, Hultgren SJ, Radford SE, Ashcroft AE, Waksman G. Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Molecular Cell. 22: 831-42. PMID 16793551 DOI: 10.1016/j.molcel.2006.05.033  0.68
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