John R. Lukens, Ph.D. - Publications

2008 University of Virginia, Charlottesville, VA 
Virology Biology, Immunology

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bolte AC, Lukens JR. Neuroimmune cleanup crews in brain injury. Trends in Immunology. PMID 33941486 DOI: 10.1016/  1
2021 Belanger MC, Ball AG, Catterton MA, Kinman AWL, Anbaei P, Groff BD, Melchor SJ, Lukens JR, Ross AE, Pompano RR. Acute Lymph Node Slices Are a Functional Model System to Study Immunity Ex Vivo. Acs Pharmacology & Translational Science. 4: 128-142. PMID 33615167 DOI: 10.1021/acsptsci.0c00143  0.01
2021 Zengeler KE, Lukens JR. Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders. Nature Reviews. Immunology. PMID 33479477 DOI: 10.1038/s41577-020-00487-7  1
2020 Zengeler KE, Lukens JR. Inflammation stresses out brain development. Nature Neuroscience. PMID 33361821 DOI: 10.1038/s41593-020-00775-4  1
2020 Satkovich J, Anderson CJ, Medina CB, Ottolini M, Lukens JR, Kendall MM. RIPK3-Dependent Recruitment of Low-Inflammatory Myeloid Cells Does Not Protect from Systemic Infection. Mbio. 11. PMID 33024046 DOI: 10.1128/mBio.02588-20  0.01
2020 Bolte AC, Dutta AB, Hurt ME, Smirnov I, Kovacs MA, McKee CA, Ennerfelt HE, Shapiro D, Nguyen BH, Frost EL, Lammert CR, Kipnis J, Lukens JR. Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. Nature Communications. 11: 4524. PMID 32913280 DOI: 10.1038/S41467-020-18113-4  1
2020 Batista SJ, Still KM, Johanson D, Thompson JA, OʼBrien CA, Lukens JR, Harris TH. Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection. Nature Communications. 11: 3687. PMID 32703941 DOI: 10.1038/S41467-020-17491-Z  0.01
2020 Ennerfelt HE, Lukens JR. The role of innate immunity in Alzheimer's disease. Immunological Reviews. PMID 32588460 DOI: 10.1111/Imr.12896  0.32
2020 Lukens JR, Anand PK. Adapt(ed) to repair - T2 immune responses in the bladder promote recurrent infections. Nature Immunology. PMID 32424364 DOI: 10.1038/S41590-020-0689-2  1
2020 Lammert CR, Frost EL, Bellinger CE, Bolte AC, McKee CA, Hurt ME, Paysour MJ, Ennerfelt HE, Lukens JR. AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment. Nature. 580: 647-652. PMID 32350463 DOI: 10.1038/S41586-020-2174-3  0.01
2020 Przanowska RK, Sobierajska E, Su Z, Jensen K, Przanowski P, Nagdas S, Kashatus JA, Kashatus DF, Bhatnagar S, Lukens JR, Dutta A. miR-206 family is important for mitochondrial and muscle function, but not essential for myogenesis in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32277852 DOI: 10.1096/Fj.201902855Rr  1
2020 Su Z, Frost EL, Lammert CR, Przanowska RK, Lukens JR, Dutta A. tRNA-derived fragments and microRNAs in the maternal-fetal interface of a mouse maternal-immune-activation autism model. Rna Biology. PMID 31983265 DOI: 10.1080/15476286.2020.1721047  1
2019 Kumar S, Lukens JR. NLRP3 sets the table for a parasitic meal. Journal of Leukocyte Biology. PMID 31063612 DOI: 10.1002/Jlb.4Ce0319-088R  0.92
2019 Paysour MJ, Bolte AC, Lukens JR. Crosstalk Between the Microbiome and Gestational Immunity in Autism-Related Disorders. Dna and Cell Biology. PMID 30817175 DOI: 10.1089/Dna.2019.4653  1
2019 Lammert CR, Lukens JR. Modeling Autism-Related Disorders in Mice with Maternal Immune Activation (MIA). Methods in Molecular Biology (Clifton, N.J.). 1960: 227-236. PMID 30798536 DOI: 10.1007/978-1-4939-9167-9_20  1
2019 Ruhl D, Du TT, Wagner EL, Hwan Choi J, Li S, Reed R, Kim K, Freeman M, Hashisaki G, Lukens JR, Shin JB. Necroptosis and apoptosis contribute to cisplatin and aminoglycoside ototoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30733218 DOI: 10.1523/Jneurosci.1384-18.2019  0.01
2019 Kumar S, Budhathoki S, Oliveira C, Lukens J, Deppmann C. P2-195: ROLE OF EXTRINSIC APOPTOSIS AND NECROPTOSIS IN ALZHEIMER'S DISEASE PATHOGENESIS Alzheimer's & Dementia. 15: P651-P651. DOI: 10.1016/J.Jalz.2019.06.2602  0.01
2018 Louveau A, Herz J, Alme MN, Salvador AF, Dong MQ, Viar KE, Herod SG, Knopp J, Setliff JC, Lupi AL, Da Mesquita S, Frost EL, Gaultier A, Harris TH, Cao R, ... ... Lukens JR, et al. CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature. Nature Neuroscience. PMID 30224810 DOI: 10.1038/S41593-018-0227-9  1
2018 Bolte AC, Lukens JR. Th17 Cells in Parkinson's Disease: The Bane of the Midbrain. Cell Stem Cell. 23: 5-6. PMID 29979991 DOI: 10.1016/J.Stem.2018.06.016  1
2018 Lammert CR, Frost EL, Bolte AC, Paysour MJ, Shaw ME, Bellinger CE, Weigel TK, Zunder ER, Lukens JR. Cutting Edge: Critical Roles for Microbiota-Mediated Regulation of the Immune System in a Prenatal Immune Activation Model of Autism. Journal of Immunology (Baltimore, Md. : 1950). PMID 29967099 DOI: 10.4049/Jimmunol.1701755  1
2017 Gharagozloo M, Gris KV, Mahvelati T, Amrani A, Lukens JR, Gris D. NLR-Dependent Regulation of Inflammation in Multiple Sclerosis- Dependent Regulation of Inflammation in Multiple Sclerosis. Frontiers in Immunology. 8: 2012. PMID 29403486 DOI: 10.3389/Fimmu.2017.02012  0.01
2017 Gurung P, Fan G, Lukens JR, Vogel P, Tonks NK, Kanneganti TD. Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease. Immunity. PMID 28410990 DOI: 10.1016/J.Immuni.2017.03.014  1
2017 Rhoads JP, Lukens JR, Wilhelm AJ, Moore JL, Mendez-Fernandez Y, Kanneganti TD, Major AS. Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9. Journal of Immunology (Baltimore, Md. : 1950). PMID 28130494 DOI: 10.4049/Jimmunol.1601563  1
2016 McKee CA, Lukens JR. Emerging Roles for the Immune System in Traumatic Brain Injury. Frontiers in Immunology. 7: 556. PMID 27994591 DOI: 10.3389/Fimmu.2016.00556  0.16
2016 Frost EL, Lukens JR. The brain's reward circuitry regulates immunity. Nature Medicine. 22: 835-7. PMID 27490435 DOI: 10.1038/Nm.4157  1
2015 Gadani SP, Walsh JT, Lukens JR, Kipnis J. Dealing with Danger in the CNS: The Response of the Immune System to Injury. Neuron. 87: 47-62. PMID 26139369 DOI: 10.1016/J.Neuron.2015.05.019  1
2015 Walsh JT, Hendrix S, Boato F, Smirnov I, Zheng J, Lukens JR, Gadani S, Hechler D, Gölz G, Rosenberger K, Kammertöns T, Vogt J, Vogelaar C, Siffrin V, Radjavi A, et al. MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. The Journal of Clinical Investigation. 125: 2547. PMID 25938785 DOI: 10.1172/JCI82458  1
2015 Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD. The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells. Immunity. 42: 654-64. PMID 25888258 DOI: 10.1016/J.Immuni.2015.03.006  1
2015 Walsh JT, Hendrix S, Boato F, Smirnov I, Zheng J, Lukens JR, Gadani S, Hechler D, Gölz G, Rosenberger K, Kammertöns T, Vogt J, Vogelaar C, Siffrin V, Radjavi A, et al. MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. The Journal of Clinical Investigation. 125: 699-714. PMID 25607842 DOI: 10.1172/Jci76210  1
2015 Edwards BA, Harris TL, Floersh H, Lukens JR, Zaki MH, Vogel P, Kanneganti TD, Bui JD, McGargill MA. Drak2 is not required for tumor surveillance and suppression. International Immunology. 27: 161-6. PMID 25568303 DOI: 10.1093/Intimm/Dxu146  1
2015 Gurung P, Lukens JR, Kanneganti TD. Mitochondria: diversity in the regulation of the NLRP3 inflammasome. Trends in Molecular Medicine. 21: 193-201. PMID 25500014 DOI: 10.1016/J.Molmed.2014.11.008  1
2014 Lukens JR, Gurung P, Vogel P, Johnson GR, Carter RA, McGoldrick DJ, Bandi SR, Calabrese CR, Vande Walle L, Lamkanfi M, Kanneganti TD. Dietary modulation of the microbiome affects autoinflammatory disease. Nature. 516: 246-9. PMID 25274309 DOI: 10.1038/Nature13788  1
2014 Lukens JR, Kanneganti TD. SHP-1 and IL-1α conspire to provoke neutrophilic dermatoses. Rare Diseases (Austin, Tex.). 2: e27742. PMID 25054090 DOI: 10.4161/rdis.27742  1
2014 Lukens JR, Kanneganti TD. Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease. Seminars in Immunopathology. 36: 595-609. PMID 24838628 DOI: 10.1007/S00281-014-0434-8  1
2014 Lukens JR, Gross JM, Calabrese C, Iwakura Y, Lamkanfi M, Vogel P, Kanneganti TD. Critical role for inflammasome-independent IL-1β production in osteomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 111: 1066-71. PMID 24395792 DOI: 10.1073/Pnas.1318688111  1
2014 Sontag TJ, Krishack PA, Lukens JR, Bhanvadia CV, Getz GS, Reardon CA. Apolipoprotein A-I protection against atherosclerosis is dependent on genetic background. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 262-9. PMID 24334873 DOI: 10.1161/Atvbaha.113.302831  1
2013 Weinlich R, Oberst A, Dillon CP, Janke LJ, Milasta S, Lukens JR, Rodriguez DA, Gurung P, Savage C, Kanneganti TD, Green DR. Protective roles for caspase-8 and cFLIP in adult homeostasis. Cell Reports. 5: 340-8. PMID 24095739 DOI: 10.1016/J.Celrep.2013.08.045  1
2013 Lukens JR, Vogel P, Johnson GR, Kelliher MA, Iwakura Y, Lamkanfi M, Kanneganti TD. RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3. Nature. 498: 224-7. PMID 23708968 DOI: 10.1038/Nature12174  1
2012 Lukens JR, Gross JM, Kanneganti TD. IL-1 family cytokines trigger sterile inflammatory disease. Frontiers in Immunology. 3: 315. PMID 23087690 DOI: 10.3389/Fimmu.2012.00315  1
2012 Lukens JR, Kanneganti TD. Fat chance: not much against NKT cells. Immunity. 37: 447-9. PMID 22999952 DOI: 10.1016/J.Immuni.2012.09.006  1
2012 Anand PK, Malireddi RK, Lukens JR, Vogel P, Bertin J, Lamkanfi M, Kanneganti TD. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature. 488: 389-93. PMID 22763455 DOI: 10.1038/Nature11250  1
2012 Lukens JR, Barr MJ, Chaplin DD, Chi H, Kanneganti TD. Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 3107-15. PMID 22345669 DOI: 10.4049/Jimmunol.1103308  1
2011 Lukens JR, Dixit VD, Kanneganti TD. Inflammasome activation in obesity-related inflammatory diseases and autoimmunity. Discovery Medicine. 12: 65-74. PMID 21794210  1
2011 Shaw PJ, Barr MJ, Lukens JR, McGargill MA, Chi H, Mak TW, Kanneganti TD. Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity. Immunity. 34: 75-84. PMID 21236705 DOI: 10.1016/J.Immuni.2010.12.015  1
2011 Wool GD, Cabana VG, Lukens J, Shaw PX, Binder CJ, Witztum JL, Reardon CA, Getz GS. 4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E-null mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 290-300. PMID 20876212 DOI: 10.1096/Fj.10-165670  1
2010 Shaw PJ, Lukens JR, Burns S, Chi H, McGargill MA, Kanneganti TD. Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 184: 4610-4. PMID 20368281 DOI: 10.4049/Jimmunol.1000217  1
2010 Lassen MG, Lukens JR, Dolina JS, Brown MG, Hahn YS. Intrahepatic IL-10 maintains NKG2A+Ly49- liver NK cells in a functionally hyporesponsive state. Journal of Immunology (Baltimore, Md. : 1950). 184: 2693-701. PMID 20124099 DOI: 10.4049/Jimmunol.0901362  1
2009 Lukens JR, Dolina JS, Kim TS, Tacke RS, Hahn YS. Liver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system. Plos One. 4: e7619. PMID 19876399 DOI: 10.1371/Journal.Pone.0007619  1
2008 Lukens JR, Cruise MW, Lassen MG, Hahn YS. Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model. Journal of Immunology (Baltimore, Md. : 1950). 180: 4875-84. PMID 18354211 DOI: 10.4049/Jimmunol.180.7.4875  1
2007 Hwang ML, Lukens JR, Bullock TN. Cognate memory CD4+ T cells generated with dendritic cell priming influence the expansion, trafficking, and differentiation of secondary CD8+ T cells and enhance tumor control. Journal of Immunology (Baltimore, Md. : 1950). 179: 5829-38. PMID 17947656 DOI: 10.4049/Jimmunol.179.9.5829  1
2006 Cruise MW, Lukens JR, Nguyen AP, Lassen MG, Waggoner SN, Hahn YS. Fas ligand is responsible for CXCR3 chemokine induction in CD4+ T cell-dependent liver damage. Journal of Immunology (Baltimore, Md. : 1950). 176: 6235-44. PMID 16670334 DOI: 10.4049/Jimmunol.176.10.6235  1
2005 Cruise MW, Melief HM, Lukens J, Soguero C, Hahn YS. Increased Fas ligand expression of CD4+ T cells by HCV core induces T cell-dependent hepatic inflammation. Journal of Leukocyte Biology. 78: 412-25. PMID 15894587 DOI: 10.1189/Jlb.0105005  1
2005 Cruise M, Lukens J, Hahn Y. Hepatitis C Viruss Immune Evasion Strategies Current Immunology Reviews. 1: 223-235. DOI: 10.2174/157339505774479275  0.01
2004 Holub JM, O'Toole-Colin K, Getzel A, Argenti A, Evans MA, Smith DC, Dalglish GA, Rifat S, Wilson DL, Taylor BM, Miott U, Glersaye J, Lam KS, McCranor BJ, Berkowitz JD, ... ... Lukens JR, et al. Lipid-lowering effects of ethyl 2-phenacyl-3-aryl-1H-pyrrole- 4-carboxylates in rodents. Molecules (Basel, Switzerland). 9: 134-57. PMID 18007418 DOI: 10.3390/90300134  1
2003 Cabana VG, Reardon CA, Feng N, Neath S, Lukens J, Getz GS. Serum paraoxonase: effect of the apolipoprotein composition of HDL and the acute phase response. Journal of Lipid Research. 44: 780-92. PMID 12562837 DOI: 10.1194/Jlr.M200432-Jlr200  1
2003 Gupton JT, Clough SC, Miller RB, Lukens JR, Henry CA, Kanters RPF, Sikorski JA. The application of vinylogous iminium salt derivatives to the synthesis of Ningalin B hexamethyl ether Tetrahedron. 59: 207-215. DOI: 10.1016/S0040-4020(02)01475-8  1
2001 Reardon CA, Kan HY, Cabana V, Blachowicz L, Lukens JR, Wu Q, Liadaki K, Getz GS, Zannis VI. In vivo studies of HDL assembly and metabolism using adenovirus-mediated transfer of apoA-I mutants in apoA-I-deficient mice Biochemistry. 40: 13670-13680. PMID 11695916 DOI: 10.1021/Bi011451E  1
2001 Reardon CA, Blachowicz L, White T, Cabana V, Wang Y, Lukens J, Bluestone J, Getz GS. Effect of immune deficiency on lipoproteins and atherosclerosis in male apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1011-6. PMID 11397712 DOI: 10.1161/01.Atv.21.6.1011  0.04
1999 Cabana VG, Reardon CA, Wei B, Lukens JR, Getz GS. SAA-only HDL formed during the acute phase response in apoA-I(+/+) and apoA-I(-/-) mice Journal of Lipid Research. 40: 1090-1103. PMID 10357841  1
1998 LaDu MJ, Gilligan SM, Lukens JR, Cabana VG, Reardon CA, Van Eldik LJ, Holtzman DM. Nascent astrocyte particles differ from lipoproteins in CSF. Journal of Neurochemistry. 70: 2070-81. PMID 9572293 DOI: 10.1046/J.1471-4159.1998.70052070.X  1
1997 LaDu MJ, Lukens JR, Reardon CA, Getz GS. Association of human, rat, and rabbit apolipoprotein E with beta-amyloid. Journal of Neuroscience Research. 49: 9-18. PMID 9211985 DOI: 10.1002/(Sici)1097-4547(19970701)49:1<9::Aid-Jnr2>3.0.Co;2-H  1
1996 Cabana VG, Lukens JR, Rice KS, Hawkins TJ, Getz GS. HDL content and composition in acute phase response in three species: Triglyceride enrichment of HDL a factor in its decrease Journal of Lipid Research. 37: 2662-2674. PMID 9017517  1
1994 O'Meara NM, Cabana VG, Lukens JR, Loharikar B, Forte TM, Polonsky KS, Getz GS. Heparin-induced lipolysis in hypertriglyceridemic subjects results in the formation of atypical HDL particles Journal of Lipid Research. 35: 2178-2190. PMID 7897316  1
1991 Lewis GF, O'Meara NM, Cabana VG, Blackman JD, Pugh WL, Druetzler AF, Lukens JR, Getz GS, Polonsky KS. Postprandial triglyceride response in Type 1 (insulin-dependent) diabetes mellitus is not altered by short-term deterioration in glycaemic control or level of postprandial insulin replacement Diabetologia. 34: 253-259. PMID 2065859 DOI: 10.1007/Bf00405084  1
1982 Lukens JR. What's in a soil survey report for me? Journal of Soil &Amp; Water Conservation. 37: 204-206.  1
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