Lakshmi Santhanam, Ph.D. - Publications

Affiliations: 
2003 Rensselaer Polytechnic Institute, Troy, NY, United States 
Area:
Chemical Engineering, Pharmacology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Oh YJ, Pau VC, Steppan J, Sikka G, Bead VR, Nyhan D, Levine BD, Berkowitz DE, Santhanam L. Role of tissue transglutaminase in age-associated ventricular stiffness. Amino Acids. PMID 27438265 DOI: 10.1007/s00726-016-2295-z  0.96
2015 Kutz JL, Greaney JL, Santhanam L, Alexander LM. Evidence for a functional vasodilatatory role for hydrogen sulphide in the human cutaneous microvasculature. The Journal of Physiology. 593: 2121-9. PMID 25639684 DOI: 10.1113/JP270054  0.96
2014 Kuo MM, Barodka V, Abraham TP, Steppan J, Shoukas AA, Butlin M, Avolio A, Berkowitz DE, Santhanam L. Measuring ascending aortic stiffness in vivo in mice using ultrasound. Journal of Visualized Experiments : Jove. PMID 25489936 DOI: 10.3791/52200  0.96
2014 Sikka G, Hussmann GP, Pandey D, Cao S, Hori D, Park JT, Steppan J, Kim JH, Barodka V, Myers AC, Santhanam L, Nyhan D, Halushka MK, Koehler RC, Snyder SH, et al. Melanopsin mediates light-dependent relaxation in blood vessels. Proceedings of the National Academy of Sciences of the United States of America. 111: 17977-82. PMID 25404319 DOI: 10.1073/Pnas.1420258111  0.96
2014 Mattison JA, Wang M, Bernier M, Zhang J, Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, Morrell C, Baur JA, Peshkin L, Sosnowska D, Csiszar A, et al. Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. Cell Metabolism. 20: 183-90. PMID 24882067 DOI: 10.1016/J.Cmet.2014.04.018  0.96
2014 Steppan J, Sikka G, Jandu S, Barodka V, Halushka MK, Flavahan NA, Belkin AM, Nyhan D, Butlin M, Avolio A, Berkowitz DE, Santhanam L. Exercise, vascular stiffness, and tissue transglutaminase. Journal of the American Heart Association. 3: e000599. PMID 24721796 DOI: 10.1161/Jaha.113.000599  0.96
2014 Barodka V, Mohanty JG, Mustafa AK, Santhanam L, Nyhan A, Bhunia AK, Sikka G, Nyhan D, Berkowitz DE, Rifkind JM. Nitroprusside inhibits calcium-induced impairment of red blood cell deformability. Transfusion. 54: 434-44. PMID 23781865 DOI: 10.1111/Trf.12291  0.96
2013 Sikka G, Pandey D, Bhuniya AK, Steppan J, Armstrong D, Santhanam L, Nyhan D, Berkowitz DE. Contribution of arginase activation to vascular dysfunction in cigarette smoking. Atherosclerosis. 231: 91-4. PMID 24125417 DOI: 10.1016/j.atherosclerosis.2013.08.026  0.96
2013 Weisbrod RM, Shiang T, Al Sayah L, Fry JL, Bajpai S, Reinhart-King CA, Lob HE, Santhanam L, Mitchell G, Cohen RA, Seta F. Arterial stiffening precedes systolic hypertension in diet-induced obesity. Hypertension. 62: 1105-10. PMID 24060894 DOI: 10.1161/Hypertensionaha.113.01744  0.96
2013 Jung SM, Jandu S, Steppan J, Belkin A, An SS, Pak A, Choi EY, Nyhan D, Butlin M, Viegas K, Avolio A, Berkowitz DE, Santhanam L. Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice. American Journal of Physiology. Heart and Circulatory Physiology. 305: H803-10. PMID 23873798 DOI: 10.1152/Ajpheart.00103.2013  0.96
2013 Smith CJ, Santhanam L, Alexander LM. Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans. Microvascular Research. 87: 58-64. PMID 23481864 DOI: 10.1016/j.mvr.2013.02.005  0.96
2013 George TJ, Arnaoutakis GJ, Beaty CA, Jandu SK, Santhanam L, Berkowitz DE, Shah AS. A physiologic and biochemical profile of clinically rejected lungs on a normothermic ex vivo lung perfusion platform. The Journal of Surgical Research. 183: 75-83. PMID 23218735 DOI: 10.1016/j.jss.2012.11.012  0.96
2013 Jandu SK, Webb AK, Pak A, Sevinc B, Nyhan D, Belkin AM, Flavahan NA, Berkowitz DE, Santhanam L. Nitric oxide regulates tissue transglutaminase localization and function in the vasculature. Amino Acids. 44: 261-9. PMID 21984378 DOI: 10.1007/S00726-011-1090-0  0.96
2012 George TJ, Arnaoutakis GJ, Beaty CA, Jandu SK, Santhanam L, Berkowitz DE, Shah AS. Inhaled hydrogen sulfide improves graft function in an experimental model of lung transplantation. The Journal of Surgical Research. 178: 593-600. PMID 22771242 DOI: 10.1016/j.jss.2012.06.037  0.96
2012 Bruning RS, Santhanam L, Stanhewicz AE, Smith CJ, Berkowitz DE, Kenney WL, Holowatz LA. Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin. Journal of Applied Physiology (Bethesda, Md. : 1985). 112: 2019-26. PMID 22500004 DOI: 10.1152/Japplphysiol.01354.2011  0.96
2012 George TJ, Arnaoutakis GJ, Beaty CA, Jandu SK, Santhanam L, Berkowitz DE, Shah AS. Hydrogen sulfide decreases reactive oxygen in a model of lung transplantation. The Journal of Surgical Research. 178: 494-501. PMID 22464394 DOI: 10.1016/j.jss.2012.02.065  0.96
2012 Khan M, Steppan J, Schuleri KH, Schuleri K, Ryoo S, Tuday E, Bugaj L, Santhanam L, Berkowitz T, Nyhan D, Shoukas AA, Berkowitz DE. Upregulation of arginase-II contributes to decreased age-related myocardial contractile reserve. European Journal of Applied Physiology. 112: 2933-41. PMID 22160208 DOI: 10.1007/s00421-011-2257-9  0.96
2011 Smith CJ, Santhanam L, Bruning RS, Stanhewicz A, Berkowitz DE, Holowatz LA. Upregulation of inducible nitric oxide synthase contributes to attenuated cutaneous vasodilation in essential hypertensive humans. Hypertension. 58: 935-42. PMID 21931069 DOI: 10.1161/HYPERTENSIONAHA.111.178129  0.96
2011 Dunn J, Gutbrod S, Webb A, Pak A, Jandu SK, Bhunia A, Berkowitz DE, Santhanam L. S-nitrosation of arginase 1 requires direct interaction with inducible nitric oxide synthase. Molecular and Cellular Biochemistry. 355: 83-9. PMID 21533769 DOI: 10.1007/s11010-011-0841-2  0.96
2011 Holowatz LA, Santhanam L, Webb A, Berkowitz DE, Kenney WL. Oral atorvastatin therapy restores cutaneous microvascular function by decreasing arginase activity in hypercholesterolaemic humans. The Journal of Physiology. 589: 2093-103. PMID 21486801 DOI: 10.1113/Jphysiol.2010.203935  0.96
2010 Santhanam L, Tuday EC, Webb AK, Dowzicky P, Kim JH, Oh YJ, Sikka G, Kuo M, Halushka MK, Macgregor AM, Dunn J, Gutbrod S, Yin D, Shoukas A, Nyhan D, et al. Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness. Circulation Research. 107: 117-25. PMID 20489165 DOI: 10.1161/Circresaha.109.215228  0.96
2010 Soucy KG, Lim HK, Attarzadeh DO, Santhanam L, Kim JH, Bhunia AK, Sevinc B, Ryoo S, Vazquez ME, Nyhan D, Shoukas AA, Berkowitz DE. Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dysfunction in rat aorta. Journal of Applied Physiology (Bethesda, Md. : 1985). 108: 1250-8. PMID 20167676 DOI: 10.1152/japplphysiol.00946.2009  0.96
2009 Kim JH, Bugaj LJ, Oh YJ, Bivalacqua TJ, Ryoo S, Soucy KG, Santhanam L, Webb A, Camara A, Sikka G, Nyhan D, Shoukas AA, Ilies M, Christianson DW, Champion HC, et al. Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 107: 1249-57. PMID 19661445 DOI: 10.1152/Japplphysiol.91393.2008  0.96
2009 Thompson-Torgerson CS, Champion HC, Santhanam L, Harris ZL, Shoukas AA. Cyclohexanone contamination from extracorporeal circuits impairs cardiovascular function. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1926-32. PMID 19411286 DOI: 10.1152/Ajpheart.00184.2009  0.96
2008 Santhanam L, Christianson DW, Nyhan D, Berkowitz DE. Arginase and vascular aging. Journal of Applied Physiology (Bethesda, Md. : 1985). 105: 1632-42. PMID 18719233 DOI: 10.1152/Japplphysiol.90627.2008  0.96
2008 Santhanam L, Gucek M, Brown TR, Mansharamani M, Ryoo S, Lemmon CA, Romer L, Shoukas AA, Berkowitz DE, Cole RN. Selective fluorescent labeling of S-nitrosothiols (S-FLOS): a novel method for studying S-nitrosation. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 19: 295-302. PMID 18706513 DOI: 10.1016/j.niox.2008.07.007  0.96
2008 Ryoo S, Gupta G, Benjo A, Lim HK, Camara A, Sikka G, Lim HK, Sohi J, Santhanam L, Soucy K, Tuday E, Baraban E, Ilies M, Gerstenblith G, Nyhan D, et al. Endothelial arginase II: a novel target for the treatment of atherosclerosis. Circulation Research. 102: 923-32. PMID 18309100 DOI: 10.1161/Circresaha.107.169573  0.96
2007 Santhanam L, Lim HK, Lim HK, Miriel V, Brown T, Patel M, Balanson S, Ryoo S, Anderson M, Irani K, Khanday F, Di Costanzo L, Nyhan D, Hare JM, Christianson DW, et al. Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction. Circulation Research. 101: 692-702. PMID 17704205 DOI: 10.1161/Circresaha.107.157727  0.96
2007 Kasuno K, Naqvi A, DeRicco J, Yamamori T, Santhanam L, Mattagajasingh I, Yang S, Meyskens FL, Bosserhoff AK, Irani K. Antagonism of p66shc by melanoma inhibitory activity Cell Death and Differentiation. 14: 1414-1421. PMID 17431427 DOI: 10.1038/Sj.Cdd.4402131  0.96
2007 Soucy KG, Lim HK, Benjo A, Santhanam L, Ryoo S, Shoukas AA, Vazquez ME, Berkowitz DE. Single exposure gamma-irradiation amplifies xanthine oxidase activity and induces endothelial dysfunction in rat aorta. Radiation and Environmental Biophysics. 46: 179-86. PMID 17256177 DOI: 10.1007/s00411-006-0090-z  0.96
2006 Steppan J, Ryoo S, Schuleri KH, Gregg C, Hasan RK, White AR, Bugaj LJ, Khan M, Santhanam L, Nyhan D, Shoukas AA, Hare JM, Berkowitz DE. Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 103: 4759-64. PMID 16537391 DOI: 10.1073/pnas.0506589103  0.96
2006 Khanday FA, Santhanam L, Kasuno K, Yamamori T, Naqvi A, Dericco J, Bugayenko A, Mattagajasingh I, Disanza A, Scita G, Irani K. Sos-mediated activation of rac1 by p66shc. The Journal of Cell Biology. 172: 817-22. PMID 16520382 DOI: 10.1083/jcb.200506001  0.96
2006 Khanday FA, Yamamori T, Mattagajasingh I, Zhang Z, Bugayenko A, Naqvi A, Santhanam L, Nabi N, Kasuno K, Day BW, Irani K. Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress. Molecular Biology of the Cell. 17: 122-9. PMID 16251354 DOI: 10.1091/Mbc.E05-06-0570  0.96
2006 Ryoo S, Santhanam L, Nyhan D, Berkowitz DE. Response to does arginase activity in vitro represent that in vivo? [2] Hypertension. 48. DOI: 10.1161/01.HYP.0000240630.65726.19  0.96
2005 Ahuja D, Santhanam L, Brooks S, Antoniotti S, Dordick JS. High-throughput biocatalysis on microarrays for synthesis and screening of small molecule therapeutics Aiche Annual Meeting, Conference Proceedings. 8704.  0.96
2004 Antoniotti S, Santhanam L, Ahuja D, Hogg MG, Dordick JS. Structural diversity of peroxidase-catalyzed oxidation products of o-methoxyphenols. Organic Letters. 6: 1975-8. PMID 15176797 DOI: 10.1021/Ol049448L  0.96
2002 Johnson DK, Schillinger KJ, Kwait DM, Hughes CV, McNamara EJ, Ishmael F, O'Donnell RW, Chang MM, Hogg MG, Dordick JS, Santhanam L, Ziegler LM, Holland JA. Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols. Endothelium : Journal of Endothelial Cell Research. 9: 191-203. PMID 12380644 DOI: 10.1080/10623320213638  0.96
2002 Santhanam L, Dordick JS. Chloroperoxidase-catalyzed epoxidation of styrene in aqueous and nonaqueous media Biocatalysis and Biotransformation. 20: 265-274. DOI: 10.1080/10242420290029481  0.96
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