| Year |
Citation |
Score |
| 2023 |
Liang D, Jiang L, Bhat SA, Missiroli S, Perrone M, Lauriola A, Adhikari R, Gudur A, Vasi Z, Ahearn I, Guardavaccaro D, Giorgi C, Philips M, Kuchay S. Palmitoylation and PDE6δ regulate membrane-compartment-specific substrate ubiquitylation and degradation. Cell Reports. 42: 111999. PMID 36662618 DOI: 10.1016/j.celrep.2023.111999 |
0.563 |
|
| 2021 |
Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng D, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, ... ... Ahearn I, et al. ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer. Nature Cancer. 2: 503-514. PMID 34142094 DOI: 10.1038/s43018-021-00208-6 |
0.461 |
|
| 2021 |
Ahearn IM, Court HR, Siddiqui F, Abankwa D, Philips MR. NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane. Life Science Alliance. 4. PMID 33579760 DOI: 10.26508/lsa.202000972 |
0.744 |
|
| 2021 |
Chen X, Yao H, Kashif M, Revêchona G, Eriksson M, Hu J, Wang T, Liu Y, Tüksammel E, Strömblad S, Ahearn IM, Philips MR, Wiel C, Ibrahim MX, Bergo MO. A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells. Elife. 10. PMID 33526168 DOI: 10.7554/eLife.63284 |
0.525 |
|
| 2020 |
Zhou M, Kuruvilla L, Shi X, Viviano S, Ahearn IM, Amendola CR, Su W, Badri S, Mahaffey J, Fehrenbacher N, Skok J, Schlessinger J, Turk BE, Calderwood DA, Philips MR. Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association. Proceedings of the National Academy of Sciences of the United States of America. PMID 33257571 DOI: 10.1073/pnas.2005712117 |
0.778 |
|
| 2019 |
Amendola CR, Mahaffey JP, Parker SJ, Ahearn IM, Chen WC, Zhou M, Court H, Shi J, Mendoza SL, Morten MJ, Rothenberg E, Gottlieb E, Wadghiri YZ, Possemato R, Hubbard SR, et al. KRAS4A directly regulates hexokinase 1. Nature. PMID 31827279 DOI: 10.1038/S41586-019-1832-9 |
0.719 |
|
| 2018 |
Ahearn I, Zhou M, Philips MR. Posttranslational Modifications of RAS Proteins. Cold Spring Harbor Perspectives in Medicine. PMID 29311131 DOI: 10.1101/Cshperspect.A031484 |
0.792 |
|
| 2017 |
Court H, Ahearn IM, Amoyel M, Bach EA, Philips MR. Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT. The Journal of Cell Biology. PMID 29051265 DOI: 10.1083/Jcb.201701053 |
0.593 |
|
| 2016 |
Zhou M, Wiener H, Su W, Zhou Y, Liot C, Ahearn I, Hancock JF, Philips MR. VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking. The Journal of Cell Biology. PMID 27502489 DOI: 10.1083/Jcb.201604061 |
0.819 |
|
| 2014 |
Tsai FD, Wynne JP, Ahearn IM, Philips MR. Metabolic labeling of Ras with tritiated palmitate to monitor palmitoylation and depalmitoylation. Methods in Molecular Biology (Clifton, N.J.). 1120: 33-41. PMID 24470017 DOI: 10.1007/978-1-62703-791-4_3 |
0.768 |
|
| 2012 |
Ahearn IM, Haigis K, Bar-Sagi D, Philips MR. Regulating the regulator: post-translational modification of RAS. Nature Reviews. Molecular Cell Biology. 13: 39-51. PMID 22189424 DOI: 10.1038/Nrm3255 |
0.77 |
|
| 2011 |
Villa CH, Dao T, Ahearn I, Fehrenbacher N, Casey E, Rey DA, Korontsvit T, Zakhaleva V, Batt CA, Philips MR, Scheinberg DA. Single-walled carbon nanotubes deliver peptide antigen into dendritic cells and enhance IgG responses to tumor-associated antigens. Acs Nano. 5: 5300-11. PMID 21682329 DOI: 10.1021/Nn200182X |
0.531 |
|
| 2011 |
Ahearn IM, Tsai FD, Court H, Zhou M, Jennings BC, Ahmed M, Fehrenbacher N, Linder ME, Philips MR. FKBP12 binds to acylated H-ras and promotes depalmitoylation. Molecular Cell. 41: 173-85. PMID 21255728 DOI: 10.1016/J.Molcel.2011.01.001 |
0.822 |
|
| 2009 |
Mor A, Wynne JP, Ahearn IM, Dustin ML, Du G, Philips MR. Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane. Molecular and Cellular Biology. 29: 3297-306. PMID 19332557 DOI: 10.1128/Mcb.00366-09 |
0.782 |
|
| 2009 |
Wright LP, Court H, Mor A, Ahearn IM, Casey PJ, Philips MR. Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe. Molecular and Cellular Biology. 29: 1826-33. PMID 19158273 DOI: 10.1128/Mcb.01719-08 |
0.777 |
|
| 2008 |
Michaelson D, Abidi W, Guardavaccaro D, Zhou M, Ahearn I, Pagano M, Philips MR. Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division. The Journal of Cell Biology. 181: 485-96. PMID 18443222 DOI: 10.1083/Jcb.200801047 |
0.767 |
|
| 2008 |
Quatela SE, Sung PJ, Ahearn IM, Bivona TG, Philips MR. Analysis of K-Ras phosphorylation, translocation, and induction of apoptosis. Methods in Enzymology. 439: 87-102. PMID 18374158 DOI: 10.1016/S0076-6879(07)00407-7 |
0.804 |
|
| 2006 |
Bivona TG, Quatela SE, Bodemann BO, Ahearn IM, Soskis MJ, Mor A, Miura J, Wiener HH, Wright L, Saba SG, Yim D, Fein A, Pérez de Castro I, Li C, Thompson CB, et al. PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis. Molecular Cell. 21: 481-93. PMID 16483930 DOI: 10.1016/J.Molcel.2006.01.012 |
0.733 |
|
| 2004 |
Bivona TG, Wiener HH, Ahearn IM, Silletti J, Chiu VK, Philips MR. Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. The Journal of Cell Biology. 164: 461-70. PMID 14757755 DOI: 10.1083/Jcb.200311093 |
0.772 |
|
| 2003 |
Bivona TG, Pérez De Castro I, Ahearn IM, Grana TM, Chiu VK, Lockyer PJ, Cullen PJ, Pellicer A, Cox AD, Philips MR. Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1. Nature. 424: 694-8. PMID 12845332 DOI: 10.1038/Nature01806 |
0.847 |
|
| 2003 |
Michaelson D, Ahearn I, Bergo M, Young S, Philips M. Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi. Molecular Biology of the Cell. 13: 3294-302. PMID 12221133 DOI: 10.1091/Mbc.E02-02-0095 |
0.688 |
|
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