Walter J. Chazin - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Biochemistry, Molecular Biology, Microbiology Biology

212 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Shi CH, Rubel C, Soss SE, Sanchez-Hodge R, Zhang S, Madrigal SC, Ravi S, McDonough H, Page RC, Chazin WJ, Patterson C, Mao CY, Willis MS, Luo HY, Li YS, et al. Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16. Plos Genetics. 14: e1007664. PMID 30222779 DOI: 10.1371/journal.pgen.1007664  0.4
2016 Sugitani N, Sivley RM, Perry KE, Capra JA, Chazin WJ. XPA: A key scaffold for human nucleotide excision repair. Dna Repair. PMID 27247238 DOI: 10.1016/j.dnarep.2016.05.018  0.96
2015 Cho H, Jeong DW, Liu Q, Yeo WS, Vogl T, Skaar EP, Chazin WJ, Bae T. Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Staphylococcus aureus Infections. Plos Pathogens. 11: e1005026. PMID 26147796 DOI: 10.1371/journal.ppat.1005026  0.96
2015 Zhao W, Vaithiyalingam S, San Filippo J, Maranon DG, Jimenez-Sainz J, Fontenay GV, Kwon Y, Leung SG, Lu L, Jensen RB, Chazin WJ, Wiese C, Sung P. Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry. Molecular Cell. PMID 26145171 DOI: 10.1016/j.molcel.2015.05.032  0.96
2015 Soss SE, Rose KL, Hill S, Jouan S, Chazin WJ. Biochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP. Plos One. 10: e0128240. PMID 26010904 DOI: 10.1371/journal.pone.0128240  0.4
2015 Brosey CA, Soss SE, Brooks S, Yan C, Ivanov I, Dorai K, Chazin WJ. Functional dynamics in replication protein a DNA binding and protein recruitment domains. Structure (London, England : 1993). 23: 1028-38. PMID 26004442 DOI: 10.1016/j.str.2015.04.008  0.96
2015 Haley KP, Delgado AG, Piazuelo MB, Mortensen BL, Correa P, Damo SM, Chazin WJ, Skaar EP, Gaddy JA. The Human Antimicrobial Protein Calgranulin C Participates in Control of Helicobacter pylori Growth and Regulation of Virulence. Infection and Immunity. 83: 2944-56. PMID 25964473 DOI: 10.1128/IAI.00544-15  0.96
2015 Chen J, Le S, Basu A, Chazin WJ, Yan J. Mechanochemical regulations of RPA's binding to ssDNA. Scientific Reports. 5: 9296. PMID 25787788 DOI: 10.1038/srep09296  0.96
2015 Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, et al. Na+ channel function, regulation, structure, trafficking and sequestration. The Journal of Physiology. 593: 1347-60. PMID 25772290 DOI: 10.1113/jphysiol.2014.281428  0.96
2015 Ning B, Feldkamp MD, Cortez D, Chazin WJ, Friedman KL, Fanning E. Simian virus Large T antigen interacts with the N-terminal domain of the 70 kD subunit of Replication Protein A in the same mode as multiple DNA damage response factors. Plos One. 10: e0116093. PMID 25706313 DOI: 10.1371/journal.pone.0116093  0.96
2015 Waterson AG, Kennedy JP, Patrone JD, Pelz NF, Feldkamp MD, Frank AO, Vangamudi B, Souza-Fagundes EM, Rossanese OW, Chazin WJ, Fesik SW. Diphenylpyrazoles as replication protein a inhibitors. Acs Medicinal Chemistry Letters. 6: 140-5. PMID 25699140 DOI: 10.1021/ml5003629  0.96
2015 Topolska-Wo? AM, Shell SM, Kila?czyk E, Szczepanowski RH, Chazin WJ, Filipek A. Dimerization and phosphatase activity of calcyclin-binding protein/Siah-1 interacting protein: the influence of oxidative stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1711-24. PMID 25609429 DOI: 10.1096/fj.14-264770  0.96
2015 Sugitani N, Chazin WJ. Characteristics and concepts of dynamic hub proteins in DNA processing machinery from studies of RPA. Progress in Biophysics and Molecular Biology. 117: 206-11. PMID 25542993 DOI: 10.1016/j.pbiomolbio.2014.12.001  0.96
2015 Soss SE, Rose KL, Hill S, Jouan S, Chazin WJ. Biochemical and proteomic analysis of ubiquitination of Hsc70 and Hsp70 by the E3 ligase CHIP Plos One. 10. DOI: 10.1371/journal.pone.0128240  0.96
2014 Gaddy JA, Radin JN, Loh JT, Piazuelo MB, Kehl-Fie TE, Delgado AG, Ilca FT, Peek RM, Cover TL, Chazin WJ, Skaar EP, Scott Algood HM. The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration. Plos Pathogens. 10: e1004450. PMID 25330071 DOI: 10.1371/journal.ppat.1004450  0.96
2014 Shuck SC, Wauchope OR, Rose KL, Kingsley PJ, Rouzer CA, Shell SM, Sugitani N, Chazin WJ, Zagol-Ikapitte I, Boutaud O, Oates JA, Galligan JJ, Beavers WN, Marnett LJ. Protein modification by adenine propenal. Chemical Research in Toxicology. 27: 1732-42. PMID 25211669 DOI: 10.1021/tx500218g  0.96
2014 Sugitani N, Shell SM, Soss SE, Chazin WJ. Redefining the DNA-binding domain of human XPA. Journal of the American Chemical Society. 136: 10830-3. PMID 25056193 DOI: 10.1021/ja503020f  0.96
2014 Makita N, Yagihara N, Crotti L, Johnson CN, Beckmann BM, Roh MS, Shigemizu D, Lichtner P, Ishikawa T, Aiba T, Homfray T, Behr ER, Klug D, Denjoy I, Mastantuono E, ... ... Chazin WJ, et al. Novel calmodulin mutations associated with congenital arrhythmia susceptibility. Circulation. Cardiovascular Genetics. 7: 466-74. PMID 24917665 DOI: 10.1161/CIRCGENETICS.113.000459  0.96
2014 Mortensen BL, Rathi S, Chazin WJ, Skaar EP. Acinetobacter baumannii response to host-mediated zinc limitation requires the transcriptional regulator Zur. Journal of Bacteriology. 196: 2616-26. PMID 24816603 DOI: 10.1128/JB.01650-14  0.96
2014 Feldkamp MD, Mason AC, Eichman BF, Chazin WJ. Structural analysis of replication protein A recruitment of the DNA damage response protein SMARCAL1. Biochemistry. 53: 3052-61. PMID 24730652 DOI: 10.1021/bi500252w  0.96
2014 Hwang HS, Nitu FR, Yang Y, Walweel K, Pereira L, Johnson CN, Faggioni M, Chazin WJ, Laver D, George AL, Cornea RL, Bers DM, Knollmann BC. Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants. Circulation Research. 114: 1114-24. PMID 24563457 DOI: 10.1161/CIRCRESAHA.114.303391  0.96
2014 Frank AO, Vangamudi B, Feldkamp MD, Souza-Fagundes EM, Luzwick JW, Cortez D, Olejniczak ET, Waterson AG, Rossanese OW, Chazin WJ, Fesik SW. Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A. Journal of Medicinal Chemistry. 57: 2455-61. PMID 24491171 DOI: 10.1021/jm401730y  0.96
2014 Vaithiyalingam S, Arnett DR, Aggarwal A, Eichman BF, Fanning E, Chazin WJ. Insights into eukaryotic primer synthesis from structures of the p48 subunit of human DNA primase. Journal of Molecular Biology. 426: 558-69. PMID 24239947 DOI: 10.1016/j.jmb.2013.11.007  0.96
2013 Stork M, Grijpstra J, Bos MP, Mañas Torres C, Devos N, Poolman JT, Chazin WJ, Tommassen J. Zinc piracy as a mechanism of Neisseria meningitidis for evasion of nutritional immunity. Plos Pathogens. 9: e1003733. PMID 24204275 DOI: 10.1371/journal.ppat.1003733  0.96
2013 Frank AO, Feldkamp MD, Kennedy JP, Waterson AG, Pelz NF, Patrone JD, Vangamudi B, Camper DV, Rossanese OW, Chazin WJ, Fesik SW. Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. Journal of Medicinal Chemistry. 56: 9242-50. PMID 24147804 DOI: 10.1021/jm401333u  0.96
2013 Shell SM, Hawkins EK, Tsai MS, Hlaing AS, Rizzo CJ, Chazin WJ. Xeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DNA. Dna Repair. 12: 947-53. PMID 24051049 DOI: 10.1016/j.dnarep.2013.08.013  0.96
2013 Feldkamp MD, Frank AO, Kennedy JP, Patrone JD, Vangamudi B, Waterson AG, Fesik SW, Chazin WJ. Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein. Biochemistry. 52: 6515-24. PMID 23962067 DOI: 10.1021/bi400542z  0.96
2013 Patrone JD, Kennedy JP, Frank AO, Feldkamp MD, Vangamudi B, Pelz NF, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW. Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A. Acs Medicinal Chemistry Letters. 4: 601-605. PMID 23914285 DOI: 10.1021/ml400032y  0.96
2013 Wells CE, Bhaskara S, Stengel KR, Zhao Y, Sirbu B, Chagot B, Cortez D, Khabele D, Chazin WJ, Cooper A, Jacques V, Rusche J, Eischen CM, McGirt LY, Hiebert SW. Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. Plos One. 8: e68915. PMID 23894374 DOI: 10.1371/journal.pone.0068915  0.96
2013 Kehl-Fie TE, Zhang Y, Moore JL, Farrand AJ, Hood MI, Rathi S, Chazin WJ, Caprioli RM, Skaar EP. MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Infection and Immunity. 81: 3395-405. PMID 23817615 DOI: 10.1128/IAI.00420-13  0.96
2013 Xu D, Young JH, Krahn JM, Song D, Corbett KD, Chazin WJ, Pedersen LC, Esko JD. Stable RAGE-heparan sulfate complexes are essential for signal transduction. Acs Chemical Biology. 8: 1611-20. PMID 23679870 DOI: 10.1021/cb4001553  0.96
2013 Soss SE, Klevit RE, Chazin WJ. Activation of UbcH5c∼Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B Biochemistry. 52: 2991-2999. PMID 23550736 DOI: 10.1021/bi3015949  0.96
2013 Damo SM, Kehl-Fie TE, Sugitani N, Holt ME, Rathi S, Murphy WJ, Zhang Y, Betz C, Hench L, Fritz G, Skaar EP, Chazin WJ. Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proceedings of the National Academy of Sciences of the United States of America. 110: 3841-6. PMID 23431180 DOI: 10.1073/pnas.1220341110  0.96
2013 Crotti L, Johnson CN, Graf E, De Ferrari GM, Cuneo BF, Ovadia M, Papagiannis J, Feldkamp MD, Rathi SG, Kunic JD, Pedrazzini M, Wieland T, Lichtner P, Beckmann BM, Clark T, ... ... Chazin WJ, et al. Calmodulin mutations associated with recurrent cardiac arrest in infants. Circulation. 127: 1009-17. PMID 23388215 DOI: 10.1161/CIRCULATIONAHA.112.001216  0.96
2013 Brosey CA, Yan C, Tsutakawa SE, Heller WT, Rambo RP, Tainer JA, Ivanov I, Chazin WJ. A new structural framework for integrating replication protein A into DNA processing machinery. Nucleic Acids Research. 41: 2313-27. PMID 23303776 DOI: 10.1093/nar/gks1332  0.96
2013 Damo SM, Feldkamp MD, Chagot B, Chazin WJ. NMR studies of the interaction of calmodulin with IQ motif peptides. Methods in Molecular Biology (Clifton, N.J.). 963: 173-86. PMID 23296611 DOI: 10.1007/978-1-62703-230-8_11  0.96
2012 Hood MI, Mortensen BL, Moore JL, Zhang Y, Kehl-Fie TE, Sugitani N, Chazin WJ, Caprioli RM, Skaar EP. Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to calprotectin-mediated zinc sequestration. Plos Pathogens. 8: e1003068. PMID 23236280 DOI: 10.1371/journal.ppat.1003068  0.96
2012 Rai V, Touré F, Chitayat S, Pei R, Song F, Li Q, Zhang J, Rosario R, Ramasamy R, Chazin WJ, Schmidt AM. Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling. The Journal of Experimental Medicine. 209: 2339-50. PMID 23209312 DOI: 10.1084/jem.20120873  0.96
2012 Brosey CA, Tsutakawa SE, Chazin WJ. Sample preparation methods to analyze DNA-induced structural changes in replication protein A. Methods in Molecular Biology (Clifton, N.J.). 922: 101-22. PMID 22976179 DOI: 10.1007/978-1-62703-032-8_6  0.96
2012 Pruneda JN, Littlefield PJ, Soss SE, Nordquist KA, Chazin WJ, Brzovic PS, Klevit RE. Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases Molecular Cell. 47: 933-942. PMID 22885007 DOI: 10.1016/j.molcel.2012.07.001  0.96
2012 Damo S, Chazin WJ, Skaar EP, Kehl-Fie TE. Inhibition of bacterial superoxide defense: a new front in the struggle between host and pathogen. Virulence. 3: 325-8. PMID 22546907 DOI: 10.4161/viru.19635  0.96
2012 Hermann A, Donato R, Weiger TM, Chazin WJ. S100 calcium binding proteins and ion channels. Frontiers in Pharmacology. 3: 67. PMID 22539925 DOI: 10.3389/fphar.2012.00067  0.96
2012 Shell SM, Chazin WJ. XPF-ERCC1: on the bubble. Structure (London, England : 1993). 20: 566-8. PMID 22483102 DOI: 10.1016/j.str.2012.03.004  0.96
2012 Liu JZ, Jellbauer S, Poe AJ, Ton V, Pesciaroli M, Kehl-Fie TE, Restrepo NA, Hosking MP, Edwards RA, Battistoni A, Pasquali P, Lane TE, Chazin WJ, Vogl T, Roth J, et al. Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. Cell Host & Microbe. 11: 227-39. PMID 22423963 DOI: 10.1016/j.chom.2012.01.017  0.96
2012 Williams CK, Vaithiyalingam S, Hammel M, Pipas J, Chazin WJ. Binding to retinoblastoma pocket domain does not alter the inter-domain flexibility of the J domain of SV40 large T antigen. Archives of Biochemistry and Biophysics. 518: 111-8. PMID 22227098 DOI: 10.1016/j.abb.2011.12.014  0.96
2012 Souza-Fagundes EM, Frank AO, Feldkamp MD, Dorset DC, Chazin WJ, Rossanese OW, Olejniczak ET, Fesik SW. A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A. Analytical Biochemistry. 421: 742-9. PMID 22197419 DOI: 10.1016/j.ab.2011.11.025  0.96
2012 Guler GD, Liu H, Vaithiyalingam S, Arnett DR, Kremmer E, Chazin WJ, Fanning E. Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress. The Journal of Biological Chemistry. 287: 6469-81. PMID 22194613 DOI: 10.1074/jbc.M111.324582  0.96
2012 Brosey CA, Chagot ME, Chazin WJ. Preparation of the modular multi-domain protein RPA for study by NMR spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 831: 181-95. PMID 22167675 DOI: 10.1007/978-1-61779-480-3_11  0.96
2012 Nelson MR, Chazin WJ. Calmodulin as a Calcium Sensor Calmodulin and Signal Transduction. 17-64. DOI: 10.1016/B978-0-08-092636-0.50006-2  0.32
2011 Liu Y, Vaithiyalingam S, Shi Q, Chazin WJ, Zinkel SS. BID binds to replication protein A and stimulates ATR function following replicative stress. Molecular and Cellular Biology. 31: 4298-309. PMID 21859891 DOI: 10.1128/MCB.05737-11  0.96
2011 Kehl-Fie TE, Chitayat S, Hood MI, Damo S, Restrepo N, Garcia C, Munro KA, Chazin WJ, Skaar EP. Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense, enhancing neutrophil killing of Staphylococcus aureus. Cell Host & Microbe. 10: 158-64. PMID 21843872 DOI: 10.1016/j.chom.2011.07.004  0.96
2011 Soss SE, Yue Y, Dhe-Paganon S, Chazin WJ. E2 conjugating enzyme selectivity and requirements for function of the E3 ubiquitin ligase CHIP. The Journal of Biological Chemistry. 286: 21277-86. PMID 21518764 DOI: 10.1074/jbc.M111.224006  0.96
2011 Chazin WJ. Relating form and function of EF-hand calcium binding proteins. Accounts of Chemical Research. 44: 171-9. PMID 21314091 DOI: 10.1021/ar100110d  0.96
2011 Chagot B, Chazin WJ. Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5. Journal of Molecular Biology. 406: 106-19. PMID 21167176 DOI: 10.1016/j.jmb.2010.11.046  0.96
2010 Koch M, Chitayat S, Dattilo BM, Schiefner A, Diez J, Chazin WJ, Fritz G. Structural basis for ligand recognition and activation of RAGE. Structure (London, England : 1993). 18: 1342-52. PMID 20947022 DOI: 10.1016/j.str.2010.05.017  0.96
2010 Robertson PD, Chagot B, Chazin WJ, Eichman BF. Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif. The Journal of Biological Chemistry. 285: 22942-9. PMID 20489205 DOI: 10.1074/jbc.M110.131276  0.96
2010 Vander Kooi CW, Ren L, Xu P, Ohi MD, Gould KL, Chazin WJ. The Prp19 WD40 domain contains a conserved protein interaction region essential for its function Structure. 18: 584-593. PMID 20462492 DOI: 10.1016/j.str.2010.02.015  0.96
2010 Huang H, Weiner BE, Zhang H, Fuller BE, Gao Y, Wile BM, Zhao K, Arnett DR, Chazin WJ, Fanning E. Structure of a DNA polymerase alpha-primase domain that docks on the SV40 helicase and activates the viral primosome. The Journal of Biological Chemistry. 285: 17112-22. PMID 20234039 DOI: 10.1074/jbc.M110.116830  0.96
2010 Pretto DI, Tsutakawa S, Brosey CA, Castillo A, Chagot ME, Smith JA, Tainer JA, Chazin WJ. Structural dynamics and single-stranded DNA binding activity of the three N-terminal domains of the large subunit of replication protein A from small angle X-ray scattering. Biochemistry. 49: 2880-9. PMID 20184389 DOI: 10.1021/bi9019934  0.96
2010 Dimitrova YN, Li J, Lee YT, Rios-Esteves J, Friedman DB, Choi HJ, Weis WI, Wang CY, Chazin WJ. Direct ubiquitination of beta-catenin by Siah-1 and regulation by the exchange factor TBL1. The Journal of Biological Chemistry. 285: 13507-16. PMID 20181957 DOI: 10.1074/jbc.M109.049411  0.96
2010 McConnell JL, Watkins GR, Soss SE, Franz HS, McCorvey LR, Spiller BW, Chazin WJ, Wadzinski BE. Alpha4 is a ubiquitin-binding protein that regulates protein serine/threonine phosphatase 2A ubiquitination. Biochemistry. 49: 1713-8. PMID 20092282 DOI: 10.1021/bi901837h  0.96
2010 Nordquist KA, Dimitrova YN, Brzovic PS, Ridenour WB, Munro KA, Soss SE, Caprioli RM, Klevit RE, Chazin WJ. Structural and functional characterization of the monomeric U-box domain from E4B. Biochemistry. 49: 347-55. PMID 20017557 DOI: 10.1021/bi901620v  0.96
2010 Ghavami S, Eshragi M, Ande SR, Chazin WJ, Klonisch T, Halayko AJ, McNeill KD, Hashemi M, Kerkhoff C, Los M. S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Cell Research. 20: 314-31. PMID 19935772 DOI: 10.1038/cr.2009.129  0.96
2010 Shell SM, Chazin WJ. Biochemical and structural domain analysis of Xeroderma pigmentosum complementation group C protein Acs Symposium Series. 1041: 59-71. DOI: 10.1021/bk-2010-1041.ch005  0.96
2010 Dimitrova YN, Li J, Lee YT, Rios-Esteves J, Friedman DB, Choi HJ, Weis WI, Wang CY, Chazin WJ. Direct ubiquitination of β-catenin by Siah-1 and regulation by the exchange factor TBL1 (The Journal Of Biological Chemistry (2010) 285, (13507-13516) DOI: 10.1074/jbc.A109.049411) Journal of Biological Chemistry. 285: 20422.  0.96
2009 Ghavami S, Chitayat S, Hashemi M, Eshraghi M, Chazin WJ, Halayko AJ, Kerkhoff C. S100A8/A9: a Janus-faced molecule in cancer therapy and tumorgenesis. European Journal of Pharmacology. 625: 73-83. PMID 19835859 DOI: 10.1016/j.ejphar.2009.08.044  0.96
2009 Sowd G, Wang H, Pretto D, Chazin WJ, Opresko PL. Replication protein A stimulates the Werner syndrome protein branch migration activity. The Journal of Biological Chemistry. 284: 34682-91. PMID 19812417 DOI: 10.1074/jbc.M109.049031  0.96
2009 Qian SB, Waldron L, Choudhary N, Klevit RE, Chazin WJ, Patterson C. Engineering a ubiquitin ligase reveals conformational flexibility required for ubiquitin transfer Journal of Biological Chemistry. 284: 26797-26802. PMID 19648119 DOI: 10.1074/jbc.M109.032334  0.96
2009 Warren EM, Huang H, Fanning E, Chazin WJ, Eichman BF. Physical interactions between Mcm10, DNA, and DNA polymerase alpha. The Journal of Biological Chemistry. 284: 24662-72. PMID 19608746 DOI: 10.1074/jbc.M109.020438  0.96
2009 Shell SM, Li Z, Shkriabai N, Kvaratskhelia M, Brosey C, Serrano MA, Chazin WJ, Musich PR, Zou Y. Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A. The Journal of Biological Chemistry. 284: 24213-22. PMID 19586908 DOI: 10.1074/jbc.M109.000745  0.96
2009 Pruitt RN, Chagot B, Cover M, Chazin WJ, Spiller B, Lacy DB. Structure-function analysis of inositol hexakisphosphate-induced autoprocessing in Clostridium difficile toxin A. The Journal of Biological Chemistry. 284: 21934-40. PMID 19553670 DOI: 10.1074/jbc.M109.018929  0.96
2009 Brosey CA, Chagot ME, Ehrhardt M, Pretto DI, Weiner BE, Chazin WJ. NMR analysis of the architecture and functional remodeling of a modular multidomain protein, RPA. Journal of the American Chemical Society. 131: 6346-7. PMID 19378948 DOI: 10.1021/ja9013634  0.96
2009 Potet F, Chagot B, Anghelescu M, Viswanathan PC, Stepanovic SZ, Kupershmidt S, Chazin WJ, Balser JR. Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin. The Journal of Biological Chemistry. 284: 8846-54. PMID 19171938 DOI: 10.1074/jbc.M806871200  0.96
2009 Zaia AA, Sappington KJ, Nisapakultorn K, Chazin WJ, Dietrich EA, Ross KF, Herzberg MC. Subversion of antimicrobial calprotectin (S100A8/S100A9 complex) in the cytoplasm of TR146 epithelial cells after invasion by Listeria monocytogenes. Mucosal Immunology. 2: 43-53. PMID 19079333 DOI: 10.1038/mi.2008.63  0.96
2009 Chagot B, Potet F, Balser JR, Chazin WJ. Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5. The Journal of Biological Chemistry. 284: 6436-45. PMID 19074138 DOI: 10.1074/jbc.M807747200  0.96
2009 Hashemi M, Chitayat S, Ande SR, Chazin WJ. Apoptosis-inducing activity of the S100A8/A9 heterodimer Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry. 8: 318-328. DOI: 10.2174/187152309789838993  0.96
2008 Warren EM, Vaithiyalingam S, Haworth J, Greer B, Bielinsky AK, Chazin WJ, Eichman BF. Structural basis for DNA binding by replication initiator Mcm10. Structure (London, England : 1993). 16: 1892-901. PMID 19081065 DOI: 10.1016/j.str.2008.10.005  0.96
2008 Xu X, Vaithiyalingam S, Glick GG, Mordes DA, Chazin WJ, Cortez D. The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling. Molecular and Cellular Biology. 28: 7345-53. PMID 18936170 DOI: 10.1128/MCB.01079-08  0.96
2008 Lee YT, Dimitrova YN, Schneider G, Ridenour WB, Bhattacharya S, Soss SE, Caprioli RM, Filipek A, Chazin WJ. Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: a novel mode for S100 protein target recognition. Biochemistry. 47: 10921-32. PMID 18803400 DOI: 10.1021/bi801233z  0.96
2008 Ghavami S, Rashedi I, Dattilo BM, Eshraghi M, Chazin WJ, Hashemi M, Wesselborg S, Kerkhoff C, Los M. S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway. Journal of Leukocyte Biology. 83: 1484-92. PMID 18339893 DOI: 10.1189/jlb.0607397  0.96
2008 Corbin BD, Seeley EH, Raab A, Feldmann J, Miller MR, Torres VJ, Anderson KL, Dattilo BM, Dunman PM, Gerads R, Caprioli RM, Nacken W, Chazin WJ, Skaar EP. Metal chelation and inhibition of bacterial growth in tissue abscesses. Science (New York, N.Y.). 319: 962-5. PMID 18276893 DOI: 10.1126/science.1152449  0.96
2008 Chazin WJ. Evolution of the NIGMS Protein Structure Initiative. Structure (London, England : 1993). 16: 12-4. PMID 18184576 DOI: 10.1016/j.str.2007.11.002  0.96
2007 Weiner BE, Huang H, Dattilo BM, Nilges MJ, Fanning E, Chazin WJ. An iron-sulfur cluster in the C-terminal domain of the p58 subunit of human DNA primase. The Journal of Biological Chemistry. 282: 33444-51. PMID 17893144 DOI: 10.1074/jbc.M705826200  0.96
2007 Chazin WJ. The impact of X-ray crystallography and NMR on intracellular calcium signal transduction by EF-hand proteins: crossing the threshold from structure to biology and medicine. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe27. PMID 17536097 DOI: 10.1126/stke.3882007pe27  0.96
2007 Dattilo BM, Fritz G, Leclerc E, Kooi CW, Heizmann CW, Chazin WJ. The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units. Biochemistry. 46: 6957-70. PMID 17508727 DOI: 10.1021/bi7003735  0.96
2007 Ball HL, Ehrhardt MR, Mordes DA, Glick GG, Chazin WJ, Cortez D. Function of a conserved checkpoint recruitment domain in ATRIP proteins. Molecular and Cellular Biology. 27: 3367-77. PMID 17339343 DOI: 10.1128/MCB.02238-06  0.96
2006 Shah VN, Chagot B, Chazin WJ. Calcium-Dependent Regulation of Ion Channels. Calcium Binding Proteins. 1: 203-212. PMID 28757812  0.6
2006 Bunick CG, Miller MR, Fuller BE, Fanning E, Chazin WJ. Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein. Biochemistry. 45: 14965-79. PMID 17154534 DOI: 10.1021/bi061370o  0.96
2006 Jiang X, Klimovich V, Arunkumar AI, Hysinger EB, Wang Y, Ott RD, Guler GD, Weiner B, Chazin WJ, Fanning E. Structural mechanism of RPA loading on DNA during activation of a simple pre-replication complex. The Embo Journal. 25: 5516-26. PMID 17110927 DOI: 10.1038/sj.emboj.7601432  0.96
2006 Shah VN, Wingo TL, Weiss KL, Williams CK, Balser JR, Chazin WJ. Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch. Proceedings of the National Academy of Sciences of the United States of America. 103: 3592-7. PMID 16505387 DOI: 10.1073/pnas.0507397103  0.96
2006 Meyn SM, Seda C, Campbell M, Weiss KL, Hu H, Pastrana-Rios B, Chazin WJ. The biochemical effect of Ser167 phosphorylation on Chlamydomonas reinhardtii centrin. Biochemical and Biophysical Research Communications. 342: 342-8. PMID 16480960 DOI: 10.1016/j.bbrc.2006.01.155  0.96
2006 Johnson E, Chazin WJ, Rance M. Effects of calcium binding on the side-chain methyl dynamics of calbindin D9k: a 2H NMR relaxation study. Journal of Molecular Biology. 357: 1237-52. PMID 16476440 DOI: 10.1016/j.jmb.2006.01.031  0.96
2006 Chandran V, Stollar EJ, Lindorff-Larsen K, Harper JF, Chazin WJ, Dobson CM, Luisi BF, Christodoulou J. Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition. Journal of Molecular Biology. 357: 400-10. PMID 16430916 DOI: 10.1016/j.jmb.2005.11.093  0.96
2006 Vander Kooi CW, Ohi MD, Rosenberg JA, Oldham ML, Newcomer ME, Gould KL, Chazin WJ. The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases Biochemistry. 45: 121-130. PMID 16388587 DOI: 10.1021/bi051787e  0.96
2006 Sheehan JH, Bunick CG, Hu H, Fagan PA, Meyn SM, Chazin WJ. Structure of the N-terminal calcium sensor domain of centrin reveals the biochemical basis for domain-specific function. The Journal of Biological Chemistry. 281: 2876-81. PMID 16317001 DOI: 10.1074/jbc.M509886200  0.96
2005 Bunick CG, Chazin WJ. Two blades of the [ex]scissor. Structure (London, England : 1993). 13: 1740-1. PMID 16338401 DOI: 10.1016/j.str.2005.11.003  0.96
2005 Nakatani Y, Yamazaki M, Chazin WJ, Yui S. Regulation of S100A8/A9 (calprotectin) binding to tumor cells by zinc ion and its implication for apoptosis-inducing activity. Mediators of Inflammation. 2005: 280-92. PMID 16258195 DOI: 10.1155/MI.2005.280  0.96
2005 Vander Kooi BT, Onuma H, Oeser JK, Svitek CA, Allen SR, Vander Kooi CW, Chazin WJ, O'Brien RM. The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements. Molecular Endocrinology (Baltimore, Md.). 19: 3001-22. PMID 16037130 DOI: 10.1210/me.2004-0497  0.96
2005 Bhattacharya S, Lee YT, Michowski W, Jastrzebska B, Filipek A, Kuznicki J, Chazin WJ. The modular structure of SIP facilitates its role in stabilizing multiprotein assemblies. Biochemistry. 44: 9462-71. PMID 15996101 DOI: 10.1021/bi0502689  0.96
2005 Malmendal A, Vander Kooi CW, Nielsen NC, Chazin WJ. Calcium-modulated S100 protein-phospholipid interactions. An NMR study of calbindin D9k and DPC. Biochemistry. 44: 6502-12. PMID 15850384 DOI: 10.1021/bi050088z  0.96
2005 Arunkumar AI, Klimovich V, Jiang X, Ott RD, Mizoue L, Fanning E, Chazin WJ. Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome. Nature Structural & Molecular Biology. 12: 332-9. PMID 15793585 DOI: 10.1038/nsmb916  0.96
2005 Ortiz M, Sanoguet Z, Hu H, Chazin WJ, McMurray CT, McMurray C, Salisbury JL, Pastrana-Rios B. Dynamics of hydrogen-deuterium exchange in Chlamydomonas centrin. Biochemistry. 44: 2409-18. PMID 15709753 DOI: 10.1021/bi0484419  0.96
2005 Ohi MD, Vander Kooi CW, Rosenberg JA, Ren L, Hirsch JP, Chazin WJ, Walz T, Gould KL. Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Molecular and Cellular Biology. 25: 451-60. PMID 15601865 DOI: 10.1128/MCB.25.1.451-460.2005  0.96
2004 Bhattacharya S, Bunick CG, Chazin WJ. Target selectivity in EF-hand calcium binding proteins. Biochimica Et Biophysica Acta. 1742: 69-79. PMID 15590057 DOI: 10.1016/j.bbamcr.2004.09.002  0.96
2004 Hu H, Sheehan JH, Chazin WJ. The mode of action of centrin. Binding of Ca2+ and a peptide fragment of Kar1p to the C-terminal domain. The Journal of Biological Chemistry. 279: 50895-903. PMID 15452116 DOI: 10.1074/jbc.M404233200  0.96
2004 Nickols HH, Shah VN, Chazin WJ, Limbird LE. Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium. The Journal of Biological Chemistry. 279: 46969-80. PMID 15319442 DOI: 10.1074/jbc.M407351200  0.96
2004 Bunick CG, Nelson MR, Mangahas S, Hunter MJ, Sheehan JH, Mizoue LS, Bunick GJ, Chazin WJ. Designing sequence to control protein function in an EF-hand protein. Journal of the American Chemical Society. 126: 5990-8. PMID 15137763 DOI: 10.1021/ja0397456  0.96
2004 Christodoulou J, Malmendal A, Harper JF, Chazin WJ. Evidence for differing roles for each lobe of the calmodulin-like domain in a calcium-dependent protein kinase. The Journal of Biological Chemistry. 279: 29092-100. PMID 15126505 DOI: 10.1074/jbc.M401297200  0.96
2004 Stauffer ME, Chazin WJ. Structural mechanisms of DNA replication, repair, and recombination. The Journal of Biological Chemistry. 279: 30915-8. PMID 15090549 DOI: 10.1074/jbc.R400015200  0.96
2004 Stauffer ME, Chazin WJ. Physical interaction between replication protein A and Rad51 promotes exchange on single-stranded DNA. The Journal of Biological Chemistry. 279: 25638-45. PMID 15056657 DOI: 10.1074/jbc.M400029200  0.96
2004 Wingo TL, Shah VN, Anderson ME, Lybrand TP, Chazin WJ, Balser JR. An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability. Nature Structural & Molecular Biology. 11: 219-25. PMID 14981509 DOI: 10.1038/nsmb737  0.96
2004 Lee YT, Jacob J, Michowski W, Nowotny M, Kuznicki J, Chazin WJ. Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain. The Journal of Biological Chemistry. 279: 16511-7. PMID 14761955 DOI: 10.1074/jbc.M400215200  0.96
2004 Bhattacharya S, Arunkumar AI, Sullivan SL, Botuyan MV, Arrowsmith CH, Chazin WJ. 1H, 13C and 15N assignments of single-stranded DNA binding domains from the 70 kDa subunit of human replication protein A. Journal of Biomolecular Nmr. 28: 195-6. PMID 14755166 DOI: 10.1023/B:JNMR.0000013818.02364.3a  0.96
2003 Bhattacharya S, Large E, Heizmann CW, Hemmings B, Chazin WJ. Structure of the Ca2+/S100B/NDR kinase peptide complex: insights into S100 target specificity and activation of the kinase. Biochemistry. 42: 14416-26. PMID 14661952 DOI: 10.1021/bi035089a  0.96
2003 Bassarello C, Cimino P, Bifulco G, Boger DL, Smith JA, Chazin WJ, Gomez-Paloma L. NMR Structure of the (+)-CPI-indole/d(GACTAATTGAC)-d(GTCAATTAGTC) Covalent Complex Chembiochem. 4: 1188-1193. PMID 14613110 DOI: 10.1002/cbic.200300642  0.96
2003 Lee JH, Park CJ, Arunkumar AI, Chazin WJ, Choi BS. NMR study on the interaction between RPA and DNA decamer containing cis-syn cyclobutane pyrimidine dimer in the presence of XPA: implication for damage verification and strand-specific dual incision in nucleotide excision repair. Nucleic Acids Research. 31: 4747-54. PMID 12907715 DOI: 10.1093/nar/gkg683  0.96
2003 Arunkumar AI, Stauffer ME, Bochkareva E, Bochkarev A, Chazin WJ. Independent and coordinated functions of replication protein A tandem high affinity single-stranded DNA binding domains. The Journal of Biological Chemistry. 278: 41077-82. PMID 12881520 DOI: 10.1074/jbc.M305871200  0.96
2003 Hu H, Chazin WJ. Unique features in the C-terminal domain provide caltractin with target specificity. Journal of Molecular Biology. 330: 473-84. PMID 12842464 DOI: 10.1016/S0022-2836(03)00619-3  0.96
2003 Bhattacharya S, Chazin WJ. Calcium-driven changes in S100A11 structure revealed. Structure (London, England : 1993). 11: 738-40. PMID 12842036 DOI: 10.1016/S0969-2126(03)00132-1  0.96
2003 Ohi MD, Vander Kooi CW, Rosenberg JA, Chazin WJ, Gould KL. Structural insights into the U-box, a domain associated with multi-ubiquitination. Nature Structural Biology. 10: 250-5. PMID 12627222 DOI: 10.1038/nsb906  0.96
2003 Malmendal A, Halpain S, Chazin WJ. Nascent structure in the kinase anchoring domain of microtubule-associated protein 2. Biochemical and Biophysical Research Communications. 301: 136-42. PMID 12535652 DOI: 10.1016/S0006-291X(02)02989-3  0.96
2002 Christodoulou J, Hu H, Chung J, Rance M, Harper JF, Chazin WJ. 1H, 15N and 13C assignments of the regulatory domains of calcium-dependent protein kinase (CDPK). Journal of Biomolecular Nmr. 23: 249-50. PMID 12238600 DOI: 10.1023/A:1019875822571  0.96
2002 Bhattacharya S, Botuyan MV, Hsu F, Shan X, Arunkumar AI, Arrowsmith CH, Edwards AM, Chazin WJ. Characterization of binding-induced changes in dynamics suggests a model for sequence-nonspecific binding of ssDNA by replication protein A. Protein Science : a Publication of the Protein Society. 11: 2316-25. PMID 12237454 DOI: 10.1110/ps.0209202  0.96
2002 Mizoue LS, Chazin WJ. Engineering and design of ligand-induced conformational change in proteins Current Opinion in Structural Biology. 12: 459-463. PMID 12163068 DOI: 10.1016/S0959-440X(02)00348-2  0.96
2002 Yui S, Nakatani Y, Hunter MJ, Chazin WJ, Yamazaki M. Implication of extracellular zinc exclusion by recombinant human calprotectin (MRP8 and MRP14) from target cells in its apoptosis-inducing activity Mediators of Inflammation. 11: 165-172. PMID 12137245 DOI: 10.1080/09622935020138208  0.96
2002 Veeraraghavan S, Fagan PA, Hu H, Lee V, Harper JF, Huang B, Chazin WJ. Structural independence of the two EF-hand domains of caltractin. The Journal of Biological Chemistry. 277: 28564-71. PMID 12034713 DOI: 10.1074/jbc.M112232200  0.96
2002 Mäler L, Sastry M, Chazin WJ. A structural basis for S100 protein specificity derived from comparative analysis of apo and Ca(2+)-calcyclin. Journal of Molecular Biology. 317: 279-90. PMID 11902843 DOI: 10.1006/jmbi.2002.5421  0.96
2002 Nelson MR, Thulin E, Fagan PA, Forsén S, Chazin WJ. The EF-hand domain: A globally cooperative structural unit Protein Science. 11: 198-205. PMID 11790829 DOI: 10.1110/ps.33302  0.96
2002 Bifulco G, Smith JA, Chazin WJ, Gomez-Paloma L. Molecular basis for recognition and binding of specific DNA sequences by calicheamicin and duocarmycin Advances in Dna Sequence-Specific Agents. 4: 47-73. DOI: 10.1016/S1067-568X(02)80005-6  0.96
2001 Akke M, Chazin WJ. An open and shut case Nature Structural Biology. 8: 910-912. PMID 11685229 DOI: 10.1038/nsb1101-910  0.96
2001 Randazzo A, Acklin C, Schäfer BW, Heizmann CW, Chazin WJ. Structural insight into human Zn2+-bound S100A2 from NMR and homology modeling Biochemical and Biophysical Research Communications. 288: 462-467. PMID 11606065 DOI: 10.1006/bbrc.2001.5793  0.96
2001 Botuyan MV, Mer G, Yi GS, Koth CM, Case DA, Edwards AM, Chazin WJ, Arrowsmith CH. Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide Journal of Molecular Biology. 312: 177-186. PMID 11545595 DOI: 10.1006/jmbi.2001.4938  0.96
2000 Mer G, Bochkarev A, Chazin WJ, Edwards AM. Three-dimensional structure and function of replication protein A Cold Spring Harbor Symposia On Quantitative Biology. 65: 193-200. PMID 12760033  0.96
2000 Mer G, Bochkarev A, Gupta R, Bochkareva E, Frappier L, Ingles CJ, Edwards AM, Chazin WJ. Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA Cell. 103: 449-456. PMID 11081631  0.96
2000 Sohnle PG, Hunter MJ, Hahn B, Chazin WJ. Zinc-reversible antimicrobial activity of recombinant calprotectin (migration inhibitory factor-related proteins 8 and 14) Journal of Infectious Diseases. 182: 1272-1275. PMID 10979933 DOI: 10.1086/315810  0.96
2000 Mer G, Edwards AM, Chazin WJ. Letter to the editor: 1H, 15N and 13C resonance assignments for the C-terminal protein interaction region of the 32 kDa subunit of human replication protein A [3] Journal of Biomolecular Nmr. 17: 179-180. PMID 10921783 DOI: 10.1023/A:1008306832408  0.96
2000 Smith JA, Bifulco G, Case DA, Boger DL, Gomez-Paloma L, Chazin WJ. The structural basis for in Situ activation of DNA alkylation by duocarmycin SA Journal of Molecular Biology. 300: 1195-1204. PMID 10903864 DOI: 10.1006/jmbi.2000.3887  0.96
2000 Koth CM, Botuyan MV, Moreland RJ, Jansma DB, Conaway JW, Conaway RC, Chazin WJ, Friesen JD, Arrowsmith CH, Edwards AM. Elongin from Saccharomyces cerevisiae. The Journal of Biological Chemistry. 275: 11174-80. PMID 10753924 DOI: 10.1074/jbc.275.15.11174  0.96
2000 Vitart V, Christodoulou J, Huang JF, Chazin WJ, Harper JF. Intramolecular activation of a Ca2+-dependent protein kinase is disrupted by insertions in the tether that connects the calmodulin-like domain to the kinase Biochemistry. 39: 4004-4011. PMID 10747788 DOI: 10.1021/bi992373m  0.96
2000 Mäler L, Blankenship J, Rance M, Chazin WJ. Site-site communication in the EF-hand Ca2+-binding protein calbindin D9k. Nature Structural Biology. 7: 245-50. PMID 10700285 DOI: 10.1038/73369  0.96
1999 Botuyan MV, Koth CM, Mer G, Chakrabartty A, Conaway JW, Conaway RC, Edwards AM, Arrowsmith CH, Chazin WJ. Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C Proceedings of the National Academy of Sciences of the United States of America. 96: 9033-9038. PMID 10430890 DOI: 10.1073/pnas.96.16.9033  0.96
1999 Mäler L, Potts BC, Chazin WJ. High resolution solution structure of apo calcyclin and structural variations in the S100 family of calcium-binding proteins. Journal of Biomolecular Nmr. 13: 233-47. PMID 10212984 DOI: 10.1023/A:1008315517955  0.96
1999 Schnell JR, Ketchem RR, Boger DL, Chazin WJ. Binding-induced activation of DNA alkylation by duocarmycin SA: Insights from the structure of an indole derivative - DNA adduct Journal of the American Chemical Society. 121: 5645-5652. DOI: 10.1021/ja983556j  0.96
1998 Nelson MR, Chazin WJ. Structures of EF-hand Ca2+-binding proteins: Diversity in the organization, packing and response to Ca2+ binding Biometals. 11: 297-318. PMID 10191495 DOI: 10.1023/A:1009253808876  0.96
1998 Wilcox SK, Putnam CD, Sastry M, Blankenship J, Chazin WJ, McRee DE, Goodin DB. Rational design of a functional metalloenzyme: Introduction of a site for manganese binding and oxidation into a heme peroxidase Biochemistry. 37: 16853-16862. PMID 9836578 DOI: 10.1021/bi9815039  0.96
1998 Kragelund BB, Jönsson M, Bifulco G, Chazin WJ, Nilsson H, Finn BE, Linse S. Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation. Biochemistry. 37: 8926-37. PMID 9636034 DOI: 10.1021/bi9726436  0.96
1998 Hunter MJ, Chazin WJ. High level expression and dimer characterization of the S100 EF-hand proteins, migration inhibitory factor-related proteins 8 and 14 Journal of Biological Chemistry. 273: 12427-12435. PMID 9575199 DOI: 10.1074/jbc.273.20.12427  0.96
1998 Potts BCM, Chazin WJ. Chemical shift homology in proteins Journal of Biomolecular Nmr. 11: 45-57. PMID 9566312  0.96
1998 Nelson MR, Chazin WJ. An interaction-based analysis of calcium-induced conformational changes in Ca2+ sensor proteins Protein Science. 7: 270-282. PMID 9521102  0.96
1998 Sastry M, Ketchem RR, Crescenzi O, Weber C, Lubienski MJ, Hidaka H, Chazin WJ. The three-dimensional structure of Ca2+-bound calcyclin: Implications for Ca2+-signal transduction by S100 proteins Structure. 6: 223-231. PMID 9519412  0.96
1998 Bifulco G, Galeone A, Nicolaou KC, Chazin WJ, Gomez-Paloma L. Solution structure of the complex between the head-to-tail dimer of calicheamicin γ1(I) oligosaccharide and a DNA duplex containing d(ACCT) and d(TCCT) high-affinity binding sites Journal of the American Chemical Society. 120: 7183-7191. DOI: 10.1021/ja973910y  0.96
1998 Mer G, Chazin WJ. Enzymatic synthesis of region-specific isotope-labeled DNA oligomers for NMR analysis Journal of the American Chemical Society. 120: 607-608. DOI: 10.1021/ja973267f  0.96
1997 Kördel J, Pearlman DA, Chazin WJ. Protein solution structure calculations in solution: Solvated molecular dynamics refinement of calbindin D9k Journal of Biomolecular Nmr. 10: 231-243. PMID 9390401  0.96
1997 Eis PS, Smith JA, Rydzewski JM, Case DA, Boger DL, Chazin WJ. High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA Journal of Molecular Biology. 272: 237-252. PMID 9299351 DOI: 10.1006/jmbi.1997.1223  0.96
1997 Miick SM, Fee RS, Millar DP, Chazin WJ. Crossover isomer bias is the primary sequence-dependent property of immobilized Holliday junctions Proceedings of the National Academy of Sciences of the United States of America. 94: 9080-9084. PMID 9256438 DOI: 10.1073/pnas.94.17.9080  0.96
1997 Lee LK, Rance M, Chazin WJ, Palmer AG. Rotational diffusion anisotropy of proteins from simultaneous analysis of 15N and 13C alpha nuclear spin relaxation. Journal of Biomolecular Nmr. 9: 287-98. PMID 9204557  0.96
1997 Chazin WJ. Two-dimensional 1H NMR studies of synthetic immobile holliday junctions Biochemistry. 30: 766-771.  0.96
1996 Potts BCM, Carlström G, Okazaki K, Hidaka H, Chazin WJ. 1H NMR assignments of apo calcyclin and comparative structural analysis with calbindin d(9k) and s 100β Protein Science. 5: 2162-2174. PMID 8931135  0.96
1996 Carlström G, Chazin WJ. Sequence dependence and direct measurement of crossover isomer distribution in model Holliday junctions using NMR spectroscopy Biochemistry. 35: 3534-3544. PMID 8639504 DOI: 10.1021/bi952571n  0.96
1996 Bifulco G, Galeone A, Gomez-Paloma L, Nicolaou KC, Chazin WJ. Solution structure of the head-to-head dimer of calicheamicin oligosaccharide domain and d(CGTAGGATATCCTACG)2 Journal of the American Chemical Society. 118: 8817-8824. DOI: 10.1021/ja961525n  0.96
1996 Smith JA, Gomez-Paloma L, Case DA, Chazin WJ. Molecular dynamics docking driven by NMR-derived restraints to determine the structure of the calicheamicin γ1I oligosaccharide domain complexed to duplex DNA Magnetic Resonance in Chemistry. 34.  0.96
1995 Carlstrom G, Chen SM, Muck S, Chazin WJ. [7] NMR studies of complex DNA structures: The holliday junction intermediate in genetic recombination Methods in Enzymology. 261: 163-182. PMID 8569494 DOI: 10.1016/S0076-6879(95)61009-X  0.96
1995 Skelton NJ, Kördel J, Chazin WJ. Determination of the solution structure of apo calbindin D9k by NMR spectroscopy Journal of Molecular Biology. 249: 441-462. PMID 7783203 DOI: 10.1006/jmbi.1995.0308  0.96
1995 Linse S, Jönsson B, Chazin WJ. The effect of protein concentration on ion binding Proceedings of the National Academy of Sciences of the United States of America. 92: 4748-4752. PMID 7761395 DOI: 10.1073/pnas.92.11.4748  0.96
1995 Akke M, Forsén S, Chazin WJ. Solution structure of (Cd2+)1-calbindin D9k reveals details of the stepwise structural changes along the Apo → (Ca2+)1II → (Ca2+)2I,II binding pathway Journal of Molecular Biology. 252: 102-121. PMID 7666423  0.96
1995 Potts BCM, Smith J, Akkeu M, Macke TJ, Okazaki K, Hidaka H, Case DA, Chazin WJ. The structure of calcyclin reveals a novel homodimeric fold for s100 ca2+-binding proteins Nature Structural Biology. 2: 790-796. PMID 7552751 DOI: 10.1038/nsb0995-790  0.96
1995 Chazin WJ. Releasing the calcium trigger Nature Structural Biology. 2: 707-710. PMID 7552734  0.96
1995 Wimberly B, Thulin E, Chazin WJ. Characterization of the N-terminal half-saturated state of calbindin D(9k): NMR studies of the N56A mutant Protein Science. 4: 1045-1055. PMID 7549869  0.96
1995 Linse S, Chazin WJ. Quantitative measurements of the cooperativity in an EF-hand protein with sequential calcium binding Protein Science. 4: 1038-1044. PMID 7549868  0.96
1994 Weber C, Lee VD, Chazin WJ, Huang B. High level expression in Escherichia coli and characterization of the EF- hand calcium-binding protein caltractin Journal of Biological Chemistry. 269: 15795-15802. PMID 8195234  0.96
1994 Skelton NJ, Kördel J, Akke M, Forsén S, Chazin WJ. Signal transduction versus buffering activity in Ca2+-binding proteins Nature Structural Biology. 1: 239-245. PMID 7656053  0.96
1994 Paloma LG, Smith JA, Chazin WJ, Nicolaou KC. Interaction of calicheamicin with duplex DNA: Role of the oligosaccharide domain and identification of multiple binding modes Journal of the American Chemical Society. 116: 3697-3708. DOI: 10.1021/ja00088a005  0.96
1993 Kördel J, Skelton NJ, Akke M, Chazin WJ. High-resolution solution structure of calcium-loaded calbindin D9k Journal of Molecular Biology. 231: 711-734. PMID 8515447  0.96
1993 Carlström G, Chazin WJ. Two-dimensional 1H nuclear magnetic resonance studies of the half-saturated (Ca2+)1 state of calbindin D9k: Further implications for the molecular basis of cooperative Ca2+ binding Journal of Molecular Biology. 231: 415-430. PMID 8389885  0.96
1993 Skelton NJ, Palmer AG, Akke M, Kordel J, Rance M, Chazin WJ. Practical Aspects of Two-Dimensional Proton-Detected 15N Spin Relaxation Measurements Journal of Magnetic Resonance, Series B. 102: 253-264. DOI: 10.1006/jmrb.1993.1095  0.96
1993 Forsén S, Kördel J, Grundström T, Chazin WJ. The molecular anatomy of a calcium-binding protein Accounts of Chemical Research. 26: 7-14.  0.96
1992 Akke M, Drakenberg T, Chazin WJ. Three-dimensional solution structure of Ca2+-loaded porcine calbindin D9k determined by nuclear magnetic resonance spectroscopy Biochemistry®. 31: 1011-1020. PMID 1734952  0.96
1992 Skelton NJ, Akke M, Kördell J, Thulin E, Forsén S, Chazin WJ. 15N NMR assignments and chemical shift analysis of uniformly labeled 15N calbindin D9k in the apo, (Cd2+)1 and (Ca2+)2 states Febs Letters. 303: 136-140. PMID 1607011 DOI: 10.1016/0014-5793(92)80505-B  0.96
1992 Chen Sm, Leupin W, Chazin WJ. Conformational studies of the duplex d-(CCAAAAATTTCC)·d-(GGAAATTTTTGG) containing a (dA)5 tract using two-dimensional 1H-n.m.r. spectroscopy International Journal of Biological Macromolecules. 14: 57-63. PMID 1596473 DOI: 10.1016/S0141-8130(05)80021-2  0.96
1992 Kördel J, Skelton NJ, Akke M, Palmer AG, Chazin WJ. Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected 15N NMR spectroscopy. Biochemistry. 31: 4856-66. PMID 1591246  0.96
1992 Chen SM, Leupin W, Rance M, Chazin WJ. Two-dimensional NMR studies of d(GGTTAATGCGGT)·d(ACCGCATTAACC) complexed with the minor groove binding drug SN-6999 Biochemistry. 31: 4406-4413. PMID 1581295  0.96
1992 Chazin WJ. NMR structures and methodology Current Opinion in Biotechnology. 3: 326-332. PMID 1368432 DOI: 10.1016/0958-1669(92)90159-G  0.96
1992 Skelton NJ, Kördel J, Akke M, Chazin WJ. Nuclear magnetic resonance studies of the internal dynamics in apo, (Cd2+)1 and (Ca2+)2 Calbindin D9k. The rates of amide proton exchange with solvent Journal of Molecular Biology. 227: 1100-1117. PMID 1331470 DOI: 10.1016/0022-2836(92)90524-N  0.96
1991 Akke M, Forsén S, Chazin WJ. Molecular basis for co-operativity in Ca2+ binding to calbindin D9k. 1H nuclear magnetic resonance studies of (Cd2+)1-bovine calbindin D9k Journal of Molecular Biology. 220: 173-189. PMID 2067016 DOI: 10.1016/0022-2836(91)90389-N  0.96
1991 Chazin WJ, Rance M, Chollet A, Luepin W. Comparative NMR analysis of the decadeoxynucleotide d-(GCATTAATGC)2 and an anlogue containing 2-aminoadenine Nucleic Acids Research. 19: 5507-5513. PMID 1945828 DOI: 10.1093/nar/19.20.5507  0.96
1991 Moore JM, Lepre CA, Gippert GP, Chazin WJ, Case DA, Wright PE. High-resolution solution structure of reduced French bean plastocyanin and comparison with the crystal structure of poplar plastocyanin Journal of Molecular Biology. 221: 533-555. PMID 1920431 DOI: 10.1016/0022-2836(91)80071-2  0.96
1991 Chazin WJ. New nuclear magnetic resonance structures and structural methodology Current Opinion in Biotechnology. 2: 520-525. PMID 1367670 DOI: 10.1016/0958-1669(91)90075-G  0.96
1991 Chazin WJ. The time dependence and efficiency of excitation of three-quantum coherence in proton spectroscopy of proteins Journal of Magnetic Resonance (1969). 91: 517-526. DOI: 10.1016/0022-2364(91)90378-7  0.96
1990 Skelton NJ, Kördel J, Forsén S, Chazin WJ. Comparative strutural analysis of the calcium free and bound states of the calcium regulatory protein calbindin D9K Journal of Molecular Biology. 213: 593-598. PMID 2359115 DOI: 10.1016/S0022-2836(05)80244-X  0.96
1990 Kördel J, Forsén S, Drakenberg T, Chazin WJ. The rate and structural consequences of proline cis-trans isomerization in calbindin D9k: NMR studies of the minor (cis-Pro43) isoform and the Pro43Gly mutant Biochemistry. 29: 4400-4409. PMID 2350544  0.96
1990 Cavanagh J, Chazin WJ, Rance M. The time dependence of coherence transfer in homonuclear isotropic mixing experiments Journal of Magnetic Resonance (1969). 87: 110-131. DOI: 10.1016/0022-2364(90)90089-R  0.96
1989 Chazin WJ, Kordel J, Drakenberg T, Thulin E, Brodin P, Grundstrom T, Forsen S. Proline isomerism leads to multiple folded conformations of calbindin D(9k): direct evidence from two-dimensional 1H NMR spectroscopy Proceedings of the National Academy of Sciences of the United States of America. 86: 2195-2198. PMID 2928325  0.96
1989 Kördel J, Forsén S, Chazin WJ. 1H NMR sequential resonance assignments, secondary structure, and global fold in solution of the major (trans-Pro43) form of bovine calbindin D9k Biochemistry. 28: 7065-7074. PMID 2819050  0.96
1989 Rance M, Chazin WJ, Dalvit C, Wright PE. Multiple-quantum nuclear magnetic resonance Methods in Enzymology. 176: 114-134. PMID 2811682 DOI: 10.1016/0076-6879(89)76008-0  0.96
1989 Drakenberg T, Hofmann T, Chazin WJ. 1H NMR studies of porcine calbindin D9k in solution: Sequential resonance assignment, secondary structure, and global fold Biochemistry. 28: 5946-5954. PMID 2775745  0.96
1989 Celda B, Widmer H, Leupin W, Chazin WJ, Denny WA, Wüthrich K. Conformational studies of d-(AAAAATTTTT)2 using constraints from nuclear overhauser effects and from quantitative analysis of the cross-peak fine structures in two-dimensional 1H nuclear magnetic resonance spectra Biochemistry. 28: 1462-1471. PMID 2719909  0.96
1989 Chazin WJ, Kördel J, Thulin E, Hofmann T, Drakenberg T, Forsén S. Identification of an isoaspartyl linkage formed upon deamidation of bovine calbindin D9k and structural characterization by 2D1H NMR Biochemistry. 28: 8646-8653. PMID 2605213  0.96
1988 Moore JM, Case DA, Chazin WJ, Gippert GP, Havel TF, Powls R, Wright PE. Three-dimensional solution structure of plastocyanin from the green alga Scenedesmus obliquus Science. 240: 314-317. PMID 3353725  0.96
1988 Chazin WJ, Hugli TE, Wright PE. 1H NMR studies of human C3a anaphylatoxin in solution: Sequential resonance assignments, secondary structure, and global fold Biochemistry. 27: 9139-9148. PMID 3266557  0.96
1988 Moore JM, Chazin WJ, Powls R, Wright PE. 1H NMR studies of plastocyanin from Scenedesmus obliquus: Complete sequence-specific assignment, secondary structure analysis, and global fold Biochemistry. 27: 7806-7816. PMID 3207712  0.96
1988 Chazin WJ, Wright PE. Complete assignment of the 1H nuclear magnetic resonance spectrum of French bean plastocyanin. Sequential resonance assignments, secondary structure and global fold Journal of Molecular Biology. 202: 623-636. PMID 3172230 DOI: 10.1016/0022-2836(88)90291-4  0.96
1988 Chazin WJ, Ranee M, Wright PE. Complete assignment of the 1H nuclear magnetic resonance spectrum of French bean plastocyanin. Application of an integrated approach to spin system identification in proteins Journal of Molecular Biology. 202: 603-622. PMID 3172229 DOI: 10.1016/0022-2836(88)90290-2  0.96
1987 Chazin WJ, Rance M, Wright PE. Complete assignment of lysine resonances in 1H NMR spectra of proteins as probes of surface structure and dynamics Febs Letters. 222: 109-114. PMID 3115827 DOI: 10.1016/0014-5793(87)80201-6  0.96
1987 Chazin WJ, Wright PE. A modified strategy for identification of 1H spin systems in proteins Biopolymers - Peptide Science Section. 26: 973-977. PMID 3038206  0.96
1987 Siekmann J, Wenzel HR, Schröder W, Schutt H, Truscheit E, Arens A, Rauenbusch E, Chazin WJ, Wüthrich K, Tschesche H. Pyroglutamyl-aprotinin, a new aprotinin homologue from bovine lungs--isolation, properties, sequence analysis and characterization using 1H nuclear magnetic resonance in solution Biological Chemistry Hoppe-Seyler. 368: 1589-1596. PMID 2450551  0.96
1987 Chazin WJ, Wüthrich K. Optimization of homonuclear relayed coherence transfer experiments with proteins in H2O solution Journal of Magnetic Resonance (1969). 72: 358-363. DOI: 10.1016/0022-2364(87)90300-3  0.96
1986 Leupin W, Chazin WJ, Hyberts S, Denny WA, Wüthrich K. NMR studies of the complex between the decadeoxynucleotide d-(GCATTAATGC)2 and a minor-groove-binding drug Biochemistry. 25: 5902-5910. PMID 3790493  0.96
1986 Chazin WJ, Wüthrich K, Hyberts S, Rance M, Denny WA, Leupin W. 1H nuclear magnetic resonance assignments for d-(GCATTAATGC)2 using experimental refinements of established procedures Journal of Molecular Biology. 190: 439-453. PMID 3783707 DOI: 10.1016/0022-2836(86)90014-8  0.96
1986 Chazin WJ, Colebrook LD. A proton spin-lattice relaxation pathway analysis of conformational preferences of aryl and enol ethers in some cinchona and morphine alkaloids Canadian Journal of Chemistry. 64: 2220-2224.  0.96
1986 Chazin WJ, Colebrook LD. Use of proton spin-lattice relaxation and nuclear overhauser effect data in structure analysis of alkaloids Journal of Organic Chemistry. 51: 1243-1253.  0.96
1985 Chazin WJ, Goldenberg DP, Creighton TE, Wüthrich K. Comparative studies of conformation and internal mobility in native and circular basic pancreatic trypsin inhibitor by 1H nuclear magnetic resonance in solution. European Journal of Biochemistry / Febs. 152: 429-37. PMID 2414103  0.96
1983 Chazin WJ, Colebrok LD, Edward JT. Relaxation pathway analysis by 1H spin-lattice relaxation and nuclear Overhauser effect difference measurements. Application to a reassignment of the 1H nmr spectrum of strychnine and to the determination of the structure and stereochemistry of some strychnine sulfonic acids Canadian Journal of Chemistry. 61: 1749-1755.  0.96
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