Gerald I. Byrne - Publications

Affiliations: 
University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Microbiology Biology

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Peters J, Byrne GI. Chlamydia trachomatis growth depends on eukaryotic cholesterol esterification and is affected by Acyl-CoA:cholesterol acyltransferase inhibition. Pathogens and Disease. 73. PMID 25883118 DOI: 10.1093/Femspd/Ftv028  0.31
2015 Grayston JT, Belland RJ, Byrne GI, Kuo CC, Schachter J, Stamm WE, Zhong G. Infection with Chlamydia pneumoniae as a cause of coronary heart disease: the hypothesis is still untested. Pathogens and Disease. 73: 1-9. PMID 25854002 DOI: 10.1093/Femspd/Ftu015  0.328
2014 Bavoil PM, Byrne GI. Analysis of CPAF mutants: new functions, new questions (the ins and outs of a chlamydial protease). Pathogens and Disease. 71: 287-91. PMID 24942261 DOI: 10.1111/2049-632X.12194  0.327
2012 Miyairi I, Ziebarth J, Laxton JD, Wang X, van Rooijen N, Williams RW, Lu L, Byrne GI, Cui Y. Host genetics and Chlamydia disease: prediction and validation of disease severity mechanisms. Plos One. 7: e33781. PMID 22438999 DOI: 10.1371/Journal.Pone.0033781  0.366
2011 Miyairi I, Laxton JD, Wang X, Obert CA, Arva Tatireddigari VR, van Rooijen N, Hatch TP, Byrne GI. Chlamydia psittaci genetic variants differ in virulence by modulation of host immunity. The Journal of Infectious Diseases. 204: 654-63. PMID 21791668 DOI: 10.1093/Infdis/Jir333  0.362
2010 Gottlieb SL, Martin DH, Xu F, Byrne GI, Brunham RC. Summary: The natural history and immunobiology of Chlamydia trachomatis genital infection and implications for Chlamydia control. The Journal of Infectious Diseases. 201: S190-204. PMID 20524236 DOI: 10.1086/652401  0.313
2010 Byrne GI. Chlamydia trachomatis strains and virulence: rethinking links to infection prevalence and disease severity. The Journal of Infectious Diseases. 201: S126-33. PMID 20470049 DOI: 10.1086/652398  0.352
2007 Miyairi I, Tatireddigari VR, Mahdi OS, Rose LA, Belland RJ, Lu L, Williams RW, Byrne GI. The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 1814-24. PMID 17641048 DOI: 10.4049/Jimmunol.179.3.1814  0.359
2007 Cao F, Castrillo A, Tontonoz P, Re F, Byrne GI. Chlamydia pneumoniae--induced macrophage foam cell formation is mediated by Toll-like receptor 2. Infection and Immunity. 75: 753-9. PMID 17145941 DOI: 10.1128/Iai.01386-06  0.334
2007 Miyairi I, Mahdi OS, Ouellette SP, Belland RJ, Byrne GI. Reply to Schachter and Dawson [6] Journal of Infectious Diseases. 195: 308-309. DOI: 10.1086/510400  0.568
2006 Ouellette SP, Hatch TP, AbdelRahman YM, Rose LA, Belland RJ, Byrne GI. Global transcriptional upregulation in the absence of increased translation in Chlamydia during IFNgamma-mediated host cell tryptophan starvation. Molecular Microbiology. 62: 1387-401. PMID 17059564 DOI: 10.1111/J.1365-2958.2006.05465.X  0.642
2006 Miyairi I, Mahdi OS, Ouellette SP, Belland RJ, Byrne GI. Different growth rates of Chlamydia trachomatis biovars reflect pathotype. The Journal of Infectious Diseases. 194: 350-7. PMID 16826483 DOI: 10.1086/505432  0.623
2006 Miyairi I, Byrne GI. Chlamydia and programmed cell death. Current Opinion in Microbiology. 9: 102-8. PMID 16406838 DOI: 10.1016/J.Mib.2005.12.004  0.305
2005 Ouellette SP, Abdelrahman YM, Belland RJ, Byrne GI. The Chlamydia pneumoniae type III secretion-related lcrH gene clusters are developmentally expressed operons. Journal of Bacteriology. 187: 7853-6. PMID 16267309 DOI: 10.1128/Jb.187.22.7853-7856.2005  0.593
2005 Robman L, Mahdi O, McCarty C, Dimitrov P, Tikellis G, McNeil J, Byrne G, Taylor H, Guymer R. Exposure to Chlamydia pneumoniae infection and progression of age-related macular degeneration. American Journal of Epidemiology. 161: 1013-9. PMID 15901621 DOI: 10.1093/Aje/Kwi130  0.316
2004 Byrne GI, Ojcius DM. Chlamydia and apoptosis: Life and death decisions of an intracellular pathogen Nature Reviews Microbiology. 2: 802-808. PMID 15378044 DOI: 10.1038/Nrmicro1007  0.41
2004 Belland RJ, Ouellette SP, Gieffers J, Byrne GI. Chlamydia pneumoniae and atherosclerosis. Cellular Microbiology. 6: 117-27. PMID 14706098 DOI: 10.1046/J.1462-5822.2003.00352.X  0.684
2004 Byrne GI, Ouellette SP, Belland RJ. Infection and atherosclerosis: mechanisms involving Chlamydia pneumoniae in cardiovascular disease International Congress Series. 1262: 426-429. DOI: 10.1016/S0531-5131(03)01862-4  0.635
2003 Gieffers J, Durling L, Ouellette SP, Rupp J, Maass M, Byrne GI, Caldwell HD, Belland RJ. Genotypic differences in the Chlamydia pneumoniae tyrP locus related to vascular tropism and pathogenicity. The Journal of Infectious Diseases. 188: 1085-93. PMID 14551876 DOI: 10.1086/378692  0.641
2003 Byrne GI. Chlamydia uncloaked. Proceedings of the National Academy of Sciences of the United States of America. 100: 8040-2. PMID 12835422 DOI: 10.1073/Pnas.1533181100  0.424
2003 Kalayoglu MV, Galvan C, Mahdi OS, Byrne GI, Mansour S. Serological association between Chlamydia pneumoniae infection and age-related macular degeneration. Archives of Ophthalmology (Chicago, Ill. : 1960). 121: 478-82. PMID 12695244 DOI: 10.1001/Archopht.121.4.478  0.356
2002 Kalayoglu MV, Libby P, Byrne GI. Chlamydia pneumoniae as an emerging risk factor in cardiovascular disease. Jama. 288: 2724-31. PMID 12460096 DOI: 10.1001/Jama.288.21.2724  0.397
2002 Gieffers J, Belland RJ, Whitmire W, Ouellette S, Crane D, Maass M, Byrne GI, Caldwell HD. Isolation of Chlamydia pneumoniae clonal variants by a focus-forming assay. Infection and Immunity. 70: 5827-34. PMID 12228314 DOI: 10.1128/Iai.70.10.5827-5834.2002  0.658
2002 Sakash JB, Byrne GI, Lichtman A, Libby P. Cytokines induce indoleamine 2,3-dioxygenase expression in human atheroma-asociated cells: implications for persistent Chlamydophila pneumoniae infection. Infection and Immunity. 70: 3959-61. PMID 12065543 DOI: 10.1128/Iai.70.7.3959-3961.2002  0.398
2002 Hahn DL, Azenabor AA, Beatty WL, Byrne GI. Chlamydia pneumoniae as a respiratory pathogen. Frontiers in Bioscience : a Journal and Virtual Library. 7: e66-76. PMID 11861211 DOI: 10.2741/Hahn  0.398
2001 Ramsey KH, Sigar IM, Rana SV, Gupta J, Holland SM, Byrne GI. Role for inducible nitric oxide synthase in protection from chronic Chlamydia trachomatis urogenital disease in mice and its regulation by oxygen free radicals Infection and Immunity. 69: 7374-7379. PMID 11705910 DOI: 10.1128/Iai.69.12.7374-7379.2001  0.357
2001 Kalayoglu MV, Perkins BN, Byrne GI. Chlamydia pneumoniae-infected monocytes exhibit increased adherence to human aortic endothelial cells. Microbes and Infection / Institut Pasteur. 3: 963-9. PMID 11580983 DOI: 10.1016/S1286-4579(01)01458-7  0.4
2001 Byrne GI, Ouellette SP, Wang Z, Rao JP, Lu L, Beatty WL, Hudson AP. Chlamydia pneumoniae expresses genes required for DNA replication but not cytokinesis during persistent infection of HEp-2 cells. Infection and Immunity. 69: 5423-9. PMID 11500413 DOI: 10.1128/Iai.69.9.5423-5429.2001  0.687
2001 Ramsey KH, Miranpuri GS, Sigar IM, Ouellette S, Byrne GI. Chlamydia trachomatis persistence in the female mouse genital tract: Inducible nitric oxide synthase and infection outcome Infection and Immunity. 69: 5131-5137. PMID 11447195 DOI: 10.1128/Iai.69.8.5131-5137.2001  0.39
2001 Mahdi OS, Kalayoglu M, Byrne GI. Emerging strategies in the diagnosis, prevention and treatment of chlamydial infections Expert Opinion On Therapeutic Patents. 11: 1253-1265. DOI: 10.1517/13543776.11.8.1253  0.37
2000 Kalayoglu MV, Indrawati, Morrison RP, Morrison SG, Yuan Y, Byrne GI. Chlamydial virulence determinants in atherogenesis: the role of chlamydial lipopolysaccharide and heat shock protein 60 in macrophage-lipoprotein interactions. The Journal of Infectious Diseases. 181: S483-9. PMID 10839744 DOI: 10.1086/315619  0.392
1999 Kalayoglu MV, Miranpuri GS, Golenbock DT, Byrne GI. Characterization of low-density lipoprotein uptake by murine macrophages exposed to Chlamydia pneumoniae. Microbes and Infection / Institut Pasteur. 1: 409-18. PMID 10602673 DOI: 10.1016/S1286-4579(99)80044-6  0.354
1999 Byrne GI, Kalayoglu MV. Chlamydia pneumoniae and atherosclerosis: links to the disease process. American Heart Journal. 138: S488-90. PMID 10539855 DOI: 10.1016/S0002-8703(99)70282-6  0.352
1999 Kalayoglu MV, Hoerneman B, LaVerda D, Morrison SG, Morrison RP, Byrne GI. Cellular oxidation of low-density lipoprotein by Chlamydia pneumoniae. The Journal of Infectious Diseases. 180: 780-90. PMID 10438367 DOI: 10.1086/314931  0.337
1999 Ramsey KH, Cotter TW, Salyer RD, Miranpuri GS, Yanez MA, Poulsen CE, DeWolfe JL, Byrne GI. Prior genital tract infection with a murine or human biovar of Chlamydia trachomatis protects mice against heterotypic challenge infection Infection and Immunity. 67: 3019-3025. PMID 10338514 DOI: 10.1128/Iai.67.6.3019-3025.1999  0.401
1999 LaVerda D, Kalayoglu MV, Byrne GI. Chlamydial heat shock proteins and disease pathology: new paradigms for old problems? Infectious Diseases in Obstetrics and Gynecology. 7: 64-71. PMID 10231012 DOI: 10.1002/(Sici)1098-0997(1999)7:1/2<64::Aid-Idog13>3.0.Co;2-I  0.375
1999 Kane CD, Vena RM, Ouellette SP, Byrne GI. Intracellular tryptophan pool sizes may account for differences in gamma interferon-mediated inhibition and persistence of chlamydial growth in polarized and nonpolarized cells. Infection and Immunity. 67: 1666-71. PMID 10085001 DOI: 10.1128/Iai.67.4.1666-1671.1999  0.664
1998 Kalayoglu MV, Byrne GI. A Chlamydia pneumoniae component that induces macrophage foam cell formation is chlamydial lipopolysaccharide. Infection and Immunity. 66: 5067-72. PMID 9784505 DOI: 10.1128/Iai.66.11.5067-5072.1998  0.433
1998 Kane CD, Byrne GI. Differential effects of gamma interferon on Chlamydia trachomatis growth in polarized and nonpolarized human epithelial cells in culture Infection and Immunity. 66: 2349-2351. PMID 9573129 DOI: 10.1128/Iai.66.5.2349-2351.1998  0.34
1998 Kalayoglu MV, Byrne GI. Induction of macrophage foam cell formation by Chlamydia pneumoniae. The Journal of Infectious Diseases. 177: 725-9. PMID 9498454 DOI: 10.1086/514241  0.375
1998 Ramsey KH, Miranpuri GS, Poulsen CE, Marthakis NB, Braune LM, Byrne GI. Inducible nitric oxide synthase does not affect resolution of murine chlamydial genital tract infections or eradication of chlamydiae in primary murine cell culture Infection and Immunity. 66: 835-838. PMID 9453651 DOI: 10.1128/Iai.66.2.835-838.1998  0.387
1997 Cotter TW, Ramsey KH, Miranpuri GS, Poulsen CE, Byrne GI. Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice Infection and Immunity. 65: 2145-2152. PMID 9169744 DOI: 10.1128/Iai.65.6.2145-2152.1997  0.389
1997 Cotter TW, Miranpuri GS, Ramsey KH, Poulsen CE, Byrne GI. Reactivation of chlamydial genital tract infection in mice Infection and Immunity. 65: 2067-2073. PMID 9169733 DOI: 10.1128/Iai.65.6.2067-2073.1997  0.341
1996 Byrne GI. Persistent Chlamydial Infections: An in Vivo Reality or a Cell Culture Artifact? Infectious Diseases in Obstetrics and Gynecology. 4: 149-151. DOI: 10.1155/S1064744996000324  0.39
1995 Beatty WL, Morrison RP, Byrne GI. Reactivation of persistent Chlamydia trachomatis infection in cell culture. Infection and Immunity. 63: 199-205. PMID 7806358 DOI: 10.1128/Iai.63.1.199-205.1995  0.432
1995 Hissong BD, Byrne GI, Padilla ML, Carlin JM. Upregulation of interferon-induced indoleamine 2,3-dioxygenase in human macrophage cultures by lipopolysaccharide, muramyl tripeptide, and interleukin-1. Cellular Immunology. 160: 264-9. PMID 7720088 DOI: 10.1016/0008-8749(95)80037-J  0.312
1994 Beatty WL, Byrne GI, Morrison RP. Repeated and persistent infection with Chlamydia and the development of chronic inflammation and disease. Trends in Microbiology. 2: 94-8. PMID 8156277 DOI: 10.1016/0966-842X(94)90542-8  0.416
1994 Paguirigan AM, Byrne GI, Becht S, Carlin JM. Cytokine-mediated indoleamine 2,3-dioxygenase induction in response to Chlamydia infection in human macrophage cultures. Infection and Immunity. 62: 1131-6. PMID 8132317  0.344
1994 Beatty WL, Belanger TA, Desai AA, Morrison RP, Byrne GI. Role of tryptophan in gamma interferon-mediated chlamydial persistence. Annals of the New York Academy of Sciences. 730: 304-6. PMID 8080194 DOI: 10.1111/J.1749-6632.1994.Tb44274.X  0.315
1994 Beatty WL, Belanger TA, Desai AA, Morrison RP, Byrne GI. Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence. Infection and Immunity. 62: 3705-11. PMID 8063385 DOI: 10.1128/Iai.62.9.3705-3711.1994  0.424
1994 Beatty WL, Morrison RP, Byrne GI. Immunoelectron-microscopic quantitation of differential levels of chlamydial proteins in a cell culture model of persistent Chlamydia trachomatis infection. Infection and Immunity. 62: 4059-62. PMID 7914884 DOI: 10.1128/Iai.62.9.4059-4062.1994  0.325
1994 Beatty WL, Morrison RP, Byrne GI. Persistent chlamydiae: from cell culture to a paradigm for chlamydial pathogenesis. Microbiological Reviews. 58: 686-99. PMID 7854252 DOI: 10.1128/Mmbr.58.4.686-699.1994  0.456
1993 Beatty WL, Byrne GI, Morrison RP. Morphologic and antigenic characterization of interferon gamma-mediated persistent Chlamydia trachomatis infection in vitro. Proceedings of the National Academy of Sciences of the United States of America. 90: 3998-4002. PMID 8387206 DOI: 10.1073/Pnas.90.9.3998  0.429
1992 Meyer KC, Cornwell R, Carlin JM, Powers C, Irizarry A, Byrne GI, Borden EC. Effects of interferons beta or gamma on neopterin biosynthesis and tryptophan degradation by human alveolar macrophages in vitro: synergy with lipopolysaccharide. American Journal of Respiratory Cell and Molecular Biology. 6: 639-46. PMID 1591013 DOI: 10.1165/Ajrcmb/6.6.639  0.331
1991 Rapoza PA, Tahija SG, Carlin JP, Miller SL, Padilla ML, Byrne GI. Effect of interferon on a primary conjunctival epithelial cell model of trachoma. Investigative Ophthalmology & Visual Science. 32: 2919-23. PMID 1917395  0.302
1989 Carlin JM, Borden EC, Byrne GI. Enhancement of indoleamine 2,3-dioxygenase activity in cancer patients receiving interferon-beta Ser. Journal of Interferon Research. 9: 167-73. PMID 2785576 DOI: 10.1089/Jir.1989.9.167  0.314
1989 Williams DM, Bonewald LF, Roodman GD, Byrne GI, Magee DM, Schachter J. Tumor necrosis factor alpha is a cytotoxin induced by murine Chlamydia trachomatis infection Infection and Immunity. 57: 1351-1355. PMID 2707849 DOI: 10.1128/Iai.57.5.1351-1355.1989  0.329
1989 Schmitz JL, Carlin JM, Borden EC, Byrne GI. Beta interferon inhibits Toxoplasma gondii growth in human monocyte-derived macrophages. Infection and Immunity. 57: 3254-6. PMID 2506136 DOI: 10.1128/Iai.57.10.3254-3256.1989  0.31
1989 Carlin JM, Borden EC, Byrne GI. Interferon-induced indoleamine 2,3-dioxygenase activity inhibits Chlamydia psittaci replication in human macrophages. Journal of Interferon Research. 9: 329-37. PMID 2501398 DOI: 10.1089/Jir.1989.9.329  0.411
1989 Guagliardi LE, Byrne GI, Paulnock DM. Differential modulation of lymphocyte proliferative responses and lymphokine secretion in mice during development of immunity to Chlamydia psittaci. Infection and Immunity. 57: 1561-7. PMID 2496033 DOI: 10.1128/Iai.57.5.1561-1567.1989  0.341
1989 Byrne GI, Carlin JM, Merkert TP, Arter DL. Long-term effects of gamma interferon on chlamydia-infected host cells: microbicidal activity follows microbistasis. Infection and Immunity. 57: 1318-20. PMID 2494116 DOI: 10.1128/Iai.57.4.1318-1320.1989  0.457
1989 Byrne GI, Schobert CS, Williams DM, Krueger DA. Characterization of gamma interferon-mediated cytotoxicity to chlamydia-infected fibroblasts. Infection and Immunity. 57: 870-4. PMID 2492975 DOI: 10.1128/Iai.57.3.870-874.1989  0.434
1989 Carlin JM, Ozaki Y, Byrne GI, Brown RR, Borden EC. Interferons and indoleamine 2,3-dioxygenase: role in antimicrobial and antitumor effects. Experientia. 45: 535-41. PMID 2472288 DOI: 10.1007/Bf01990503  0.354
1989 Carlin JM, Borden EC, Sondel PM, Byrne GI. Interferon-induced indoleamine 2,3-dioxygenase activity in human mononuclear phagocytes. Journal of Leukocyte Biology. 45: 29-34. PMID 2463322 DOI: 10.1002/Jlb.45.1.29  0.343
1988 Williams DM, Byrne GI, Grubbs B, Marshal TJ, Schachter J. Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice Infection and Immunity. 56: 3004-3006. PMID 3139569 DOI: 10.1128/Iai.56.11.3004-3006.1988  0.34
1988 Byrne GI, Grubbs B, Marshall TJ, Schachter J, Williams DM. Gamma interferon-mediated cytotoxicity related to murine Chlamydia trachomatis infection Infection and Immunity. 56: 2023-2027. PMID 3135268 DOI: 10.1128/Iai.56.8.2023-2027.1988  0.418
1988 Huebner RE, Byrne GI. In vivo-activated mononuclear phagocytes and protective immunity to chlamydiae in mice Infection and Immunity. 56: 1492-1499. PMID 3131246  0.312
1988 Byrne GI, Guagliardi LE, Huebner RE, Paulnock DM. Immunomodulation and Chlamydia: immunosuppression and the protective immune response to C. psittaci in mice. Advances in Experimental Medicine and Biology. 239: 343-52. PMID 3059773 DOI: 10.1007/978-1-4757-5421-6_33  0.351
1987 Mørland B, Byrne GI, Jones TC. The effect of intracellular Chlamydia psittaci on lysosomal enzyme activities in mouse peritoneal macrophages Acta Pathologica Microbiologica Et Immunologica Scandinavica - Section C Immunology. 95: 291-293. PMID 3442238 DOI: 10.1111/J.1699-0463.1987.Tb00043.X  0.325
1986 Byrne GI, Lehmann LK, Kirschbaum JG, Borden EC, Lee CM, Brown RR. Induction of tryptophan degradation in vitro and in vivo: A γ-interferon stimulated activity Journal of Interferon Research. 6: 389-396. PMID 3095441 DOI: 10.1089/Jir.1986.6.389  0.329
1986 Byrne GI, Lehmann LK, Landry GJ. Induction of tryptophan catabolism is the mechanism for gamma-interferon-mediated inhibition of intracellular Chlamydia psittaci replication in T24 cells. Infection and Immunity. 53: 347-51. PMID 3089936 DOI: 10.1128/Iai.53.2.347-351.1986  0.384
1983 Murray HW, Byrne GI, Rothermel CD, Cartelli DM. Lymphokine enhances oxygen-independent activity against intracellular pathogens Journal of Experimental Medicine. 158: 234-239. PMID 6864162 DOI: 10.1084/Jem.158.1.234  0.327
1983 Byrne GI, Rothermel CD. Differential susceptibility of chlamydiae to exogenous fibroblast interferon Infection and Immunity. 39: 1004-1005. PMID 6832807 DOI: 10.1128/Iai.39.2.1004-1005.1983  0.388
1983 Byrne GI, Krueger DA. Lymphokine-mediated inhibition of Chlamydia replication in mouse fibroblasts is neutralized by anti-gamma interferon immunoglobulin. Infection and Immunity. 42: 1152-8. PMID 6417024  0.322
1983 Rothermel CD, Byrne GI, Havell EA. Effect of interferon on the growth of Chlamydia trachomatis in mouse fibroblasts (L cells) Infection and Immunity. 39: 362-370. PMID 6185434  0.335
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