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Robert S. Lahue - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Genetics, Microbiology Biology
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lahue RS. New developments in Huntington's disease and other triplet repeat diseases: DNA repair turns to the dark side. Neuronal Signaling. 4: NS20200010. PMID 33224521 DOI: 10.1042/NS20200010  0.434
2020 Williams GM, Paschalis V, Ortega J, Muskett FW, Hodgkinson JT, Li GM, Schwabe JWR, Lahue RS. HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions. Proceedings of the National Academy of Sciences of the United States of America. PMID 32900932 DOI: 10.1073/Pnas.2013223117  0.488
2020 Williams GM, Lahue RS. Assessing Triplet Repeat Expansions in Human SVG-A Cell Culture. Methods in Molecular Biology (Clifton, N.J.). 2056: 151-172. PMID 31586347 DOI: 10.1007/978-1-4939-9784-8_10  0.372
2017 Keogh N, Chan KY, Li GM, Lahue RS. MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions. Nucleic Acids Research. 45: 10068-10078. PMID 28973443 DOI: 10.1093/Nar/Gkx650  0.47
2017 Suelves N, Kirkham-McCarthy L, Lahue RS, Ginés S. A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice. Scientific Reports. 7: 6082. PMID 28729730 DOI: 10.1038/S41598-017-05125-2  0.323
2016 Ye Y, Kirkham-McCarthy L, Lahue RS. The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination. Dna Repair. 43: 1-8. PMID 27173583 DOI: 10.1016/J.Dnarep.2016.04.012  0.613
2014 Frizzell A, Nguyen JH, Petalcorin MI, Turner KD, Boulton SJ, Freudenreich CH, Lahue RS. RTEL1 inhibits trinucleotide repeat expansions and fragility. Cell Reports. 6: 827-35. PMID 24561255 DOI: 10.1016/J.Celrep.2014.01.034  0.526
2014 Concannon C, Lahue RS. Nucleotide excision repair and the 26S proteasome function together to promote trinucleotide repeat expansions. Dna Repair. 13: 42-9. PMID 24359926 DOI: 10.1016/J.Dnarep.2013.11.004  0.605
2013 Concannon C, Lahue RS. The 26S proteasome drives trinucleotide repeat expansions. Nucleic Acids Research. 41: 6098-108. PMID 23620289 DOI: 10.1093/Nar/Gkt295  0.467
2013 Stevens JR, Lahue EE, Li GM, Lahue RS. Trinucleotide repeat expansions catalyzed by human cell-free extracts. Cell Research. 23: 565-72. PMID 23337586 DOI: 10.1038/Cr.2013.12  0.578
2012 Gannon AM, Frizzell A, Healy E, Lahue RS. MutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells. Nucleic Acids Research. 40: 10324-33. PMID 22941650 DOI: 10.1093/Nar/Gks810  0.502
2012 Lahue RS, Frizzell A. Histone deacetylase complexes as caretakers of genome stability. Epigenetics. 7: 806-10. PMID 22722985 DOI: 10.4161/Epi.20922  0.485
2012 Debacker K, Frizzell A, Gleeson O, Kirkham-McCarthy L, Mertz T, Lahue RS. Histone deacetylase complexes promote trinucleotide repeat expansions. Plos Biology. 10: e1001257. PMID 22363205 DOI: 10.1371/Journal.Pbio.1001257  0.493
2011 Gellon L, Razidlo DF, Gleeson O, Verra L, Schulz D, Lahue RS, Freudenreich CH. New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion. Plos Genetics. 7: e1001298. PMID 21347277 DOI: 10.1371/Journal.Pgen.1001298  0.724
2008 Erlich RL, Fry RC, Begley TJ, Daee DL, Lahue RS, Samson LD. Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae. Plos One. 3: e3717. PMID 19005567 DOI: 10.1371/Journal.Pone.0003717  0.72
2008 Sommer D, Stith CM, Burgers PM, Lahue RS. Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae. Nucleic Acids Research. 36: 4699-707. PMID 18628298 DOI: 10.1093/Nar/Gkn446  0.572
2008 Dhar A, Lahue RS. Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae. Nucleic Acids Research. 36: 3366-73. PMID 18440969 DOI: 10.1093/Nar/Gkn225  0.546
2008 Razidlo DF, Lahue RS. Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. Dna Repair. 7: 633-40. PMID 18321795 DOI: 10.1016/J.Dnarep.2008.01.009  0.731
2007 Claassen DA, Lahue RS. Expansions of CAG.CTG repeats in immortalized human astrocytes. Human Molecular Genetics. 16: 3088-96. PMID 17881653 DOI: 10.1093/Hmg/Ddm270  0.486
2007 Daee DL, Mertz T, Lahue RS. Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae. Molecular and Cellular Biology. 27: 102-10. PMID 17060452 DOI: 10.1128/Mcb.01167-06  0.748
2007 Collins NS, Bhattacharyya S, Lahue RS. Rev1 enhances CAG.CTG repeat stability in Saccharomyces cerevisiae. Dna Repair. 6: 38-44. PMID 16979389 DOI: 10.1016/J.Dnarep.2006.08.002  0.628
2006 Farrell BT, Lahue RS. CAG*CTG repeat instability in cultured human astrocytes. Nucleic Acids Research. 34: 4495-505. PMID 16945950 DOI: 10.1093/Nar/Gkl614  0.387
2005 Pelletier R, Farrell BT, Miret JJ, Lahue RS. Mechanistic features of CAG*CTG repeat contractions in cultured cells revealed by a novel genetic assay. Nucleic Acids Research. 33: 5667-76. PMID 16199754 DOI: 10.1093/Nar/Gki880  0.419
2005 Bhattacharyya S, Lahue RS. Srs2 helicase of Saccharomyces cerevisiae selectively unwinds triplet repeat DNA. The Journal of Biological Chemistry. 280: 33311-7. PMID 16085654 DOI: 10.1074/Jbc.M503325200  0.584
2004 Corrette-Bennett SE, Borgeson C, Sommer D, Burgers PM, Lahue RS. DNA polymerase delta, RFC and PCNA are required for repair synthesis of large looped heteroduplexes in Saccharomyces cerevisiae. Nucleic Acids Research. 32: 6268-75. PMID 15576353 DOI: 10.1093/Nar/Gkh965  0.565
2004 Bhattacharyya S, Lahue RS. Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats. Molecular and Cellular Biology. 24: 7324-30. PMID 15314145 DOI: 10.1128/Mcb.24.17.7324-7330.2004  0.634
2004 Dixon MJ, Bhattacharyya S, Lahue RS. Genetic assays for triplet repeat instability in yeast. Methods in Molecular Biology (Clifton, N.J.). 277: 29-45. PMID 15201447 DOI: 10.1385/1-59259-804-8:029  0.368
2004 Dixon MJ, Lahue RS. DNA elements important for CAG*CTG repeat thresholds in Saccharomyces cerevisiae. Nucleic Acids Research. 32: 1289-97. PMID 14982954 DOI: 10.1093/Nar/Gkh292  0.456
2004 Lahue RS. DNA mismatch repair and trinucleotide repeat instability: The expansion connection Chemtracts. 17: 677-681.  0.461
2003 Lahue RS, Slater DL. DNA repair and trinucleotide repeat instability. Frontiers in Bioscience : a Journal and Virtual Library. 8: s653-65. PMID 12700078 DOI: 10.2741/1107  0.583
2003 Pelletier R, Krasilnikova MM, Samadashwily GM, Lahue R, Mirkin SM. Replication and expansion of trinucleotide repeats in yeast. Molecular and Cellular Biology. 23: 1349-57. PMID 12556494 DOI: 10.1128/Mcb.23.4.1349-1357.2003  0.453
2002 Dixon MJ, Lahue RS. Examining the potential role of DNA polymerases eta and zeta in triplet repeat instability in yeast. Dna Repair. 1: 763-70. PMID 12509280 DOI: 10.1016/S1568-7864(02)00095-2  0.615
2002 Bhattacharyya S, Rolfsmeier ML, Dixon MJ, Wagoner K, Lahue RS. Identification of RTG2 as a modifier gene for CTG*CAG repeat instability in Saccharomyces cerevisiae. Genetics. 162: 579-89. PMID 12399373  0.429
2002 Bhattacharyya S, Rolfsmeier ML, Dixon MJ, Wagoner K, Lahue RS. Identification of RTG2 as a modifier gene for CTG·CAG repeat instability in Saccharomyces cerevisiae Genetics. 162: 579-589.  0.427
2001 Corrette-Bennett SE, Mohlman NL, Rosado Z, Miret JJ, Hess PM, Parker BO, Lahue RS. Efficient repair of large DNA loops in Saccharomyces cerevisiae. Nucleic Acids Research. 29: 4134-43. PMID 11600702 DOI: 10.1093/Nar/29.20.4134  0.494
2001 Rolfsmeier ML, Dixon MJ, Pessoa-Brandão L, Pelletier R, Miret JJ, Lahue RS. Cis-elements governing trinucleotide repeat instability in Saccharomyces cerevisiae Genetics. 157: 1569-1579. PMID 11290713  0.35
2000 Rolfsmeier ML, Dixon MJ, Lahue RS. Mismatch repair blocks expansions of interrupted trinucleotide repeats in yeast Molecular Cell. 6: 1501-1507. PMID 11163222 DOI: 10.1016/S1097-2765(00)00146-5  0.532
2000 Rolfsmeier ML, Lahue RS. Stabilizing effects of interruptions on trinucleotide repeat expansions in Saccharomyces cerevisiae Molecular and Cellular Biology. 20: 173-180. PMID 10594019 DOI: 10.1128/Mcb.20.1.173-180.2000  0.53
1999 Spiro C, Pelletier R, Rolfsmeier ML, Dixon MJ, Lahue RS, Gupta G, Park MS, Chen X, Mariappan SVS, McMurray CT. Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats Molecular Cell. 4: 1079-1085. PMID 10635332 DOI: 10.1016/S1097-2765(00)80236-1  0.482
1999 Corrette-Bennett SE, Lahue RS. Mismatch repair assay Methods in Molecular Biology (Clifton, N.J.). 113: 121-132. PMID 10443415 DOI: 10.1385/1-59259-675-4:121  0.426
1999 Corrette-Bennett SE, Parker BO, Mohlman NL, Lahue RS. Correction of large mispaired DNA loops by extracts of Saccharomyces cerevisiae Journal of Biological Chemistry. 274: 17605-17611. PMID 10364197 DOI: 10.1074/Jbc.274.25.17605  0.542
1998 Miret JJ, Pessoa-Brandão L, Lahue RS. Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 95: 12438-12443. PMID 9770504 DOI: 10.1073/Pnas.95.21.12438  0.52
1997 Selva EM, Maderazo AB, Lahue RS. Differential effects of the mismatch repair genes MSH2 and MSH3 on homeologous recombination in Saccharomyces cerevisiae Molecular and General Genetics. 257: 71-82. PMID 9439571 DOI: 10.1007/Pl00008619  0.47
1997 Miret JJ, Pessoa-Brandão L, Lahue RS. Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae Molecular and Cellular Biology. 17: 3382-3387. PMID 9154837 DOI: 10.1128/Mcb.17.6.3382  0.447
1997 Alani E, Sokolsky T, Studamire B, Miret JJ, Lahue RS. Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition. Molecular and Cellular Biology. 17: 2436-47. PMID 9111312 DOI: 10.1128/Mcb.17.5.2436  0.457
1997 Selva EM, Maderazo AB, Lahue RS. Differential effects of the mismatch repair genes Molecular Genetics and Genomics. 257: 71. DOI: 10.1007/S004380050625  0.353
1996 Modrich P, Lahue R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology Annual Review of Biochemistry. 65: 101-133. PMID 8811176 DOI: 10.1146/Annurev.Bi.65.070196.000533  0.563
1996 Miret JJ, Parker BO, Lahue RS. Recognition of DNA insertion/deletion mismatches by an activity in Saccharomyces cerevisiae Nucleic Acids Research. 24: 721-729. PMID 8604316 DOI: 10.1093/Nar/24.4.721  0.404
1995 Selva EM, New L, Crouse GF, Lahue RS. Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae. Genetics. 139: 1175-88. PMID 7768431  0.394
1993 Cooper DL, Lahue RS, Modrich P. Methyl-directed mismatch repair is bidirectional. The Journal of Biological Chemistry. 268: 11823-9. PMID 8389365  0.375
1989 Lahue RS, Au KG, Modrich P. DNA mismatch correction in a defined system Science. 245: 160-164. PMID 2665076 DOI: 10.1126/Science.2665076  0.483
1988 Lahue RS, Modrich P. Methyl-directed DNA mismatch repair in Escherichia coli Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 198: 37-43. PMID 3280983 DOI: 10.1016/0027-5107(88)90037-1  0.4
1987 Lahue RS, Su SS, Modrich P. Requirement for d(GATC) sequences in Escherichia coli mutHLS mismatch correction. Proceedings of the National Academy of Sciences of the United States of America. 84: 1482-6. PMID 3550791 DOI: 10.1073/Pnas.84.6.1482  0.401
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