Dana Gabuzda, M.D. - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Virology Biology, Microbiology Biology
Website:
http://www.dfhcc.harvard.edu/insider/member-detail/member/dana-h-gabuzda-md/

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lorenz DR, Misra V, Chettimada S, Uno H, Wang L, Blount BC, De Jesús VR, Gelman BB, Morgello S, Wolinsky SM, Gabuzda D. Acrolein and other toxicant exposures in relation to cardiovascular disease among marijuana and tobacco smokers in a longitudinal cohort of HIV-positive and negative adults. Eclinicalmedicine. 31: 100697. PMID 33554087 DOI: 10.1016/j.eclinm.2020.100697  0.64
2020 Chettimada S, Lorenz DR, Misra V, Wolinsky SM, Gabuzda D. Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients. Bmc Immunology. 21: 57. PMID 33176710 DOI: 10.1186/s12865-020-00386-5  0.64
2020 Mukerji SS, Misra V, Lorenz DR, Chettimada S, Keller K, Letendre S, Ellis RJ, Morgello S, Parker RA, Gabuzda D. Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy. The Journal of Infectious Diseases. PMID 32157292 DOI: 10.1093/infdis/jiaa104  0.64
2019 Guha D, Lorenz DR, Misra V, Chettimada S, Morgello S, Gabuzda D. Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment. Journal of Neuroinflammation. 16: 254. PMID 31805958 DOI: 10.1186/s12974-019-1617-y  0.64
2019 Lorenz DR, Misra V, Gabuzda D. Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms. Human Genomics. 13: 59. PMID 31779701 DOI: 10.1186/s40246-019-0247-x  0.64
2019 Solomon IH, Chettimada S, Misra V, Lorenz DR, Gorelick RJ, Gelman BB, Morgello S, Gabuzda D. White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy. Molecular Neurobiology. PMID 31691183 DOI: 10.1007/s12035-019-01795-3  0.64
2019 Lorenz DR, Uno H, Wolinsky SM, Gabuzda D. Effect of marijuana smoking on pulmonary disease in HIV-infected and uninfected men: a longitudinal cohort study. Eclinicalmedicine. 7: 55-64. PMID 30854514 DOI: 10.1016/j.eclinm.2019.01.003  0.4
2018 Guha D, Mukerji SS, Chettimada S, Misra V, Lorenz DR, Morgello S, Gabuzda D. CSF extracellular vesicles and neurofilament light protein as biomarkers of CNS injury in HIV-infected patients on antiretroviral therapy. Aids (London, England). PMID 30557159 DOI: 10.1097/QAD.0000000000002121  0.64
2018 Aldersley J, Lorenz DR, Misra V, Uno H, Gabuzda D. Increased risk of anal squamous cell carcinoma in HIV-positive men with prior HBV infection. Aids (London, England). PMID 30325778 DOI: 10.1097/QAD.0000000000002059  0.64
2018 Dutta A, Uno H, Lorenz DR, Wolinsky SM, Gabuzda D. Low T-cell subsets prior to development of virus-associated cancer in HIV-seronegative men who have sex with men. Cancer Causes & Control : Ccc. PMID 30315476 DOI: 10.1007/s10552-018-1090-4  0.4
2018 Chettimada S, Lorenz DR, Misra V, Dillon ST, Reeves RK, Manickam C, Morgello S, Kirk GD, Mehta SH, Gabuzda D. Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy. Scientific Reports. 8: 7227. PMID 29740045 DOI: 10.1038/s41598-018-25515-4  0.64
2018 Mukerji SS, Misra V, Lorenz DR, Uno H, Morgello S, Franklin D, Ellis RJ, Letendre S, Gabuzda D. Impact of Antiretroviral Regimens on CSF Viral Escape in a Prospective Multicohort Study of ART-Experienced HIV-1 Infected Adults in the United States. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 29617912 DOI: 10.1093/cid/ciy267  0.64
2017 Mukerji S, Haghighat R, Misra V, Lorenz DR, Holman A, Dutta A, Gabuzda D. Longitudinal Modeling of Depressive Trajectories Among HIV-Infected Men Using Cocaine. Aids and Behavior. PMID 28550378 DOI: 10.1007/s10461-017-1801-y  0.64
2017 Dutta A, Uno H, Holman A, Lorenz DR, Wolinsky SM, Gabuzda D. Long-term nitrite inhalant exposure and cancer risk in MSM. Aids (London, England). 31: 1169-1180. PMID 28441176 DOI: 10.1097/QAD.0000000000001451  0.4
2017 Mukerji SS, Misra V, Lorenz D, Cervantes-Arslanian AM, Lyons J, Chalkias S, Wurcel A, Burke D, Venna N, Morgello S, Koralnik IJ, Gabuzda D. Temporal Patterns and Drug Resistance in CSF Viral Escape Among ART-experienced HIV-1 Infected Adults. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 28328546 DOI: 10.1097/QAI.0000000000001362  0.64
2017 Dutta A, Uno H, Holman A, Lorenz DR, Wolinsky SM, Gabuzda D. Long-term nitrite inhalant exposure and cancer risk in men who have sex with men: a prospective cohort study. Aids (London, England). PMID 28323751 DOI: 10.1097/QAD.0000000000001451  0.4
2017 Solomon IH, De Girolami U, Chettimada S, Misra V, Singer EJ, Gabuzda D. Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era. Bmc Infectious Diseases. 17: 151. PMID 28212619 DOI: 10.1186/s12879-017-2246-7  0.64
2016 Mukerji SS, Locascio JJ, Misra V, Lorenz DR, Holman A, Dutta A, Penugonda S, Wolinsky SM, Gabuzda D. Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 27448678 DOI: 10.1093/cid/ciw495  0.84
2015 Pery E, Sheehy A, Miranda Nebane N, Misra V, Mankowski MK, Rasmussen L, Lucile White E, Ptak RG, Gabuzda D. Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1. Virology. 484: 276-87. PMID 26141568 DOI: 10.1016/j.virol.2015.06.014  0.64
2015 Cassol E, Misra V, Morgello S, Kirk GD, Mehta SH, Gabuzda D. Altered Monoamine and Acylcarnitine Metabolites in HIV-Positive and HIV-Negative Subjects With Depression. Journal of Acquired Immune Deficiency Syndromes (1999). 69: 18-28. PMID 25942456 DOI: 10.1097/QAI.0000000000000551  0.84
2015 Mefford ME, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5. Virology. 481: 210-22. PMID 25797607 DOI: 10.1016/j.virol.2015.01.032  0.84
2015 Pery E, Sheehy A, Nebane NM, Brazier AJ, Misra V, Rajendran KS, Buhrlage SJ, Mankowski MK, Rasmussen L, White EL, Ptak RG, Gabuzda D. Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein. The Journal of Biological Chemistry. 290: 10504-17. PMID 25724652 DOI: 10.1074/jbc.M114.626903  0.84
2015 Pery E, Sheehy A, Miranda Nebane N, Misra V, Mankowski MK, Rasmussen L, Lucile White E, Ptak RG, Gabuzda D. Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1 Virology. 484: 276-287. DOI: 10.1016/j.virol.2015.06.014  0.84
2014 Yen PJ, Mefford ME, Hoxie JA, Williams KC, Desrosiers RC, Gabuzda D. Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques. Virology. 458: 53-68. PMID 24928039 DOI: 10.1016/j.virol.2014.03.024  0.84
2014 Cassol E, Misra V, Dutta A, Morgello S, Gabuzda D. Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment. Aids (London, England). 28: 1579-91. PMID 24752083 DOI: 10.1097/QAD.0000000000000303  0.84
2014 Yen PJ, Herschhorn A, Haim H, Salas I, Gu C, Sodroski J, Gabuzda D. Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission. Journal of Virology. 88: 5014-28. PMID 24554659 DOI: 10.1128/JVI.02785-13  0.84
2013 Cassol E, Misra V, Morgello S, Gabuzda D. Applications and limitations of inflammatory biomarkers for studies on neurocognitive impairment in HIV infection. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 1087-97. PMID 24259252 DOI: 10.1007/s11481-013-9512-2  0.84
2013 Cassol E, Misra V, Holman A, Kamat A, Morgello S, Gabuzda D. Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors. Bmc Infectious Diseases. 13: 203. PMID 23641933 DOI: 10.1186/1471-2334-13-203  0.84
2013 Gabuzda D, Yankner BA. Physiology: Inflammation links ageing to the brain. Nature. 497: 197-8. PMID 23636321 DOI: 10.1038/nature12100  0.84
2013 Cassol E, Cassetta L, Rizzi C, Gabuzda D, Alfano M, Poli G. Dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitro. Aids (London, England). 27: 707-16. PMID 23211775 DOI: 10.1097/QAD.0b013e32835cfc82  0.84
2012 Holman AG, Gabuzda D. A machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia. Plos One. 7: e49538. PMID 23166702 DOI: 10.1371/journal.pone.0049538  0.84
2012 Yan Z, Shah PK, Amin SB, Samur MK, Huang N, Wang X, Misra V, Ji H, Gabuzda D, Li C. Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers. Nucleic Acids Research. 40: e135. PMID 22645320 DOI: 10.1093/nar/gks395  0.84
2012 Kamat A, Lyons JL, Misra V, Uno H, Morgello S, Singer EJ, Gabuzda D. Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection. Journal of Acquired Immune Deficiency Syndromes (1999). 60: 234-43. PMID 22569268 DOI: 10.1097/QAI.0b013e318256f3bc  0.84
2012 Mukerji J, Olivieri KC, Misra V, Agopian KA, Gabuzda D. Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation. Retrovirology. 9: 33. PMID 22534017 DOI: 10.1186/1742-4690-9-33  0.84
2012 Kamat A, Misra V, Cassol E, Ancuta P, Yan Z, Li C, Morgello S, Gabuzda D. A plasma biomarker signature of immune activation in HIV patients on antiretroviral therapy. Plos One. 7: e30881. PMID 22363505 DOI: 10.1371/journal.pone.0030881  0.84
2011 Olivieri KC, Mukerji J, Gabuzda D. Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2. Retrovirology. 8: 64. PMID 21819585 DOI: 10.1186/1742-4690-8-64  0.84
2011 Lyons JL, Uno H, Ancuta P, Kamat A, Moore DJ, Singer EJ, Morgello S, Gabuzda D. Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection. Journal of Acquired Immune Deficiency Syndromes (1999). 57: 371-9. PMID 21646912 DOI: 10.1097/QAI.0b013e3182237e54  0.84
2011 Gray LR, Gabuzda D, Cowley D, Ellett A, Chiavaroli L, Wesselingh SL, Churchill MJ, Gorry PR. CD4 and MHC class 1 down-modulation activities of nef alleles from brain- and lymphoid tissue-derived primary HIV-1 isolates. Journal of Neurovirology. 17: 82-91. PMID 21165790 DOI: 10.1007/s13365-010-0001-6  0.84
2010 Holman AG, Mefford ME, O'Connor N, Gabuzda D. HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites. Aids Research and Therapy. 7: 43. PMID 21156070 DOI: 10.1186/1742-6405-7-43  0.84
2010 Kamat A, Ancuta P, Blumberg RS, Gabuzda D. Serological markers for inflammatory bowel disease in AIDS patients with evidence of microbial translocation. Plos One. 5: e15533. PMID 21125014 DOI: 10.1371/journal.pone.0015533  0.84
2010 Olivieri KC, Agopian KA, Mukerji J, Gabuzda D. Evidence for adaptive evolution at the divergence between lymphoid and brain HIV-1 nef genes. Aids Research and Human Retroviruses. 26: 495-500. PMID 20377428 DOI: 10.1089/aid.2009.0257  0.84
2009 Ancuta P, Liu KY, Misra V, Wacleche VS, Gosselin A, Zhou X, Gabuzda D. Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets. Bmc Genomics. 10: 403. PMID 19712453 DOI: 10.1186/1471-2164-10-403  0.84
2009 Dunfee RL, Thomas ER, Gabuzda D. Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12. Retrovirology. 6: 69. PMID 19619305 DOI: 10.1186/1742-4690-6-69  0.84
2009 Gray L, Roche M, Churchill MJ, Sterjovski J, Ellett A, Poumbourios P, Sherieff S, Sheffief S, Wang B, Saksena N, Purcell DF, Wesselingh S, Cunningham AL, Brew BJ, Gabuzda D, et al. Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain. Journal of Virology. 83: 5430-41. PMID 19321618 DOI: 10.1128/JVI.02648-08  0.84
2009 Pery E, Rajendran KS, Brazier AJ, Gabuzda D. Regulation of APOBEC3 proteins by a novel YXXL motif in human immunodeficiency virus type 1 Vif and simian immunodeficiency virus SIVagm Vif. Journal of Virology. 83: 2374-81. PMID 19109396 DOI: 10.1128/JVI.01898-08  0.84
2008 Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA. Evolution of the aging brain transcriptome and synaptic regulation. Plos One. 3: e3329. PMID 18830410 DOI: 10.1371/journal.pone.0003329  0.84
2008 Mefford ME, Gorry PR, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic prediction programs underestimate the frequency of CXCR4 usage by R5X4 HIV type 1 in brain and other tissues. Aids Research and Human Retroviruses. 24: 1215-20. PMID 18788913 DOI: 10.1089/aid.2008.0009  0.84
2008 Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. Plos One. 3: e2516. PMID 18575590 DOI: 10.1371/journal.pone.0002516  0.84
2008 Wang J, Shackelford JM, Selliah N, Shivers DK, O'Neill E, Garcia JV, Muthumani K, Weiner D, Yu XF, Gabuzda D, Finkel TH. The HIV-1 Vif protein mediates degradation of Vpr and reduces Vpr-induced cell cycle arrest. Dna and Cell Biology. 27: 267-77. PMID 18462066 DOI: 10.1089/dna.2007.0707  0.84
2007 Sterjovski J, Churchill MJ, Ellett A, Gray LR, Roche MJ, Dunfee RL, Purcell DF, Saksena N, Wang B, Sonza S, Wesselingh SL, Karlsson I, Fenyo EM, Gabuzda D, Cunningham AL, et al. Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS. Retrovirology. 4: 89. PMID 18076768 DOI: 10.1186/1742-4690-4-89  0.84
2007 Mehle A, Wilson H, Zhang C, Brazier AJ, McPike M, Pery E, Gabuzda D. Identification of an APOBEC3G binding site in human immunodeficiency virus type 1 Vif and inhibitors of Vif-APOBEC3G binding. Journal of Virology. 81: 13235-41. PMID 17898068 DOI: 10.1128/JVI.00204-07  0.84
2007 Gorry PR, McPhee DA, Verity E, Dyer WB, Wesselingh SL, Learmont J, Sullivan JS, Roche M, Zaunders JJ, Gabuzda D, Crowe SM, Mills J, Lewin SR, Brew BJ, Cunningham AL, et al. Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo. Retrovirology. 4: 66. PMID 17888184 DOI: 10.1186/1742-4690-4-66  0.84
2007 Gray L, Churchill MJ, Sterjovski J, Witlox K, Learmont JC, Sullivan JS, Wesselingh SL, Gabuzda D, Cunningham AL, McPhee DA, Gorry PR. Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source. Virology Journal. 4: 75. PMID 17634131 DOI: 10.1186/1743-422X-4-75  0.4
2007 Dunfee RL, Thomas ER, Wang J, Kunstman K, Wolinsky SM, Gabuzda D. Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia. Virology. 367: 222-34. PMID 17599380 DOI: 10.1016/j.virol.2007.05.029  0.84
2007 Verity EE, Zotos D, Wilson K, Chatfield C, Lawson VA, Dwyer DE, Cunningham A, Learmont J, Dyer W, Sullivan J, Churchill M, Wesselingh SL, Gabuzda D, Gorry PR, McPhee DA. Viral phenotypes and antibody responses in long-term survivors infected with attenuated human immunodeficiency virus type 1 containing deletions in the nef and long terminal repeat regions. Journal of Virology. 81: 9268-78. PMID 17567690 DOI: 10.1128/JVI.00650-07  0.84
2007 Thomas ER, Dunfee RL, Stanton J, Bogdan D, Kunstman K, Wolinsky SM, Gabuzda D. High frequency of defective vpu compared with tat and rev genes in brain from patients with HIV type 1-associated dementia. Aids Research and Human Retroviruses. 23: 575-80. PMID 17451348 DOI: 10.1089/aid.2006.0246  0.84
2007 Gorry PR, Dunfee RL, Mefford ME, Kunstman K, Morgan T, Moore JP, Mascola JR, Agopian K, Holm GH, Mehle A, Taylor J, Farzan M, Wang H, Ellery P, Willey SJ, ... ... Gabuzda D, et al. Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology. 362: 163-78. PMID 17239419 DOI: 10.1016/j.virol.2006.11.025  0.84
2007 Thomas ER, Dunfee RL, Stanton J, Bogdan D, Taylor J, Kunstman K, Bell JE, Wolinsky SM, Gabuzda D. Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion. Virology. 360: 105-19. PMID 17084877 DOI: 10.1016/j.virol.2006.09.036  0.84
2007 Agopian K, Wei BL, Garcia JV, Gabuzda D. CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable. Virology. 358: 119-35. PMID 16979207 DOI: 10.1016/j.virol.2006.07.053  0.84
2006 Wang J, Gabuzda D. Reconstitution of human immunodeficiency virus-induced neurodegeneration using isolated populations of human neurons, astrocytes, and microglia and neuroprotection mediated by insulin-like growth factors. Journal of Neurovirology. 12: 472-91. PMID 17162663 DOI: 10.1080/13550280601039659  0.84
2006 Ancuta P, Wang J, Gabuzda D. CD16+ monocytes produce IL-6, CCL2, and matrix metalloproteinase-9 upon interaction with CX3CL1-expressing endothelial cells. Journal of Leukocyte Biology. 80: 1156-64. PMID 17056766 DOI: 10.1189/jlb.0206125  0.84
2006 Dunfee RL, Thomas ER, Gorry PR, Wang J, Taylor J, Kunstman K, Wolinsky SM, Gabuzda D. The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia. Proceedings of the National Academy of Sciences of the United States of America. 103: 15160-5. PMID 17015824 DOI: 10.1073/pnas.0605513103  0.84
2006 Dunfee R, Thomas ER, Gorry PR, Wang J, Ancuta P, Gabuzda D. Mechanisms of HIV-1 neurotropism. Current Hiv Research. 4: 267-78. PMID 16842080 DOI: 10.2174/157016206777709500  0.84
2006 Churchill MJ, Gorry PR, Cowley D, Lal L, Sonza S, Purcell DF, Thompson KA, Gabuzda D, McArthur JC, Pardo CA, Wesselingh SL. Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues. Journal of Neurovirology. 12: 146-52. PMID 16798676 DOI: 10.1080/13550280600748946  0.84
2006 Reche PA, Keskin DB, Hussey RE, Ancuta P, Gabuzda D, Reinherz EL. Elicitation from virus-naive individuals of cytotoxic T lymphocytes directed against conserved HIV-1 epitopes. Medical Immunology (London, England). 5: 1. PMID 16674822 DOI: 10.1186/1476-9433-5-1  0.84
2006 Ancuta P, Autissier P, Wurcel A, Zaman T, Stone D, Gabuzda D. CD16+ monocyte-derived macrophages activate resting T cells for HIV infection by producing CCR3 and CCR4 ligands. Journal of Immunology (Baltimore, Md. : 1950). 176: 5760-71. PMID 16670281  0.84
2006 Mehle A, Thomas ER, Rajendran KS, Gabuzda D. A zinc-binding region in Vif binds Cul5 and determines cullin selection. The Journal of Biological Chemistry. 281: 17259-65. PMID 16636053 DOI: 10.1074/jbc.M602413200  0.84
2006 Gray L, Churchill MJ, Keane N, Sterjovski J, Ellett AM, Purcell DF, Poumbourios P, Kol C, Wang B, Saksena NK, Wesselingh SL, Price P, French M, Gabuzda D, Gorry PR. Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5delta32 allele. Journal of Virology. 80: 3684-91. PMID 16537640 DOI: 10.1128/JVI.80.7.3684-3691.2006  0.84
2006 Agopian K, Wei BL, Garcia JV, Gabuzda D. A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2. Journal of Virology. 80: 3050-61. PMID 16501114 DOI: 10.1128/JVI.80.6.3050-3061.2006  0.84
2006 Ancuta P, Kunstman KJ, Autissier P, Zaman T, Stone D, Wolinsky SM, Gabuzda D. CD16+ monocytes exposed to HIV promote highly efficient viral replication upon differentiation into macrophages and interaction with T cells. Virology. 344: 267-76. PMID 16305804 DOI: 10.1016/j.virol.2005.10.027  0.84
2005 Louder MK, Sambor A, Chertova E, Hunte T, Barrett S, Ojong F, Sanders-Buell E, Zolla-Pazner S, McCutchan FE, Roser JD, Gabuzda D, Lifson JD, Mascola JR. HIV-1 envelope pseudotyped viral vectors and infectious molecular clones expressing the same envelope glycoprotein have a similar neutralization phenotype, but culture in peripheral blood mononuclear cells is associated with decreased neutralization sensitivity. Virology. 339: 226-38. PMID 16005039 DOI: 10.1016/j.virol.2005.06.003  0.84
2005 Farrow MA, Somasundaran M, Zhang C, Gabuzda D, Sullivan JL, Greenough TC. Nuclear localization of HIV type 1 Vif isolated from a long-term asymptomatic individual and potential role in virus attenuation. Aids Research and Human Retroviruses. 21: 565-74. PMID 15989462 DOI: 10.1089/aid.2005.21.565  0.84
2005 Holm GH, Gabuzda D. Distinct mechanisms of CD4+ and CD8+ T-cell activation and bystander apoptosis induced by human immunodeficiency virus type 1 virions. Journal of Virology. 79: 6299-311. PMID 15858014 DOI: 10.1128/JVI.79.10.6299-6311.2005  0.84
2005 Gorry PR, Churchill M, Crowe SM, Cunningham AL, Gabuzda D. Pathogenesis of macrophage tropic HIV-1. Current Hiv Research. 3: 53-60. PMID 15638723 DOI: 10.2174/1570162052772951  0.84
2004 Mehle A, Goncalves J, Santa-Marta M, McPike M, Gabuzda D. Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation. Genes & Development. 18: 2861-6. PMID 15574592 DOI: 10.1101/gad.1249904  0.84
2004 Ancuta P, Moses A, Gabuzda D. Transendothelial migration of CD16+ monocytes in response to fractalkine under constitutive and inflammatory conditions. Immunobiology. 209: 11-20. PMID 15481136 DOI: 10.1016/j.imbio.2004.04.001  0.84
2004 Wang J, Babcock GJ, Choe H, Farzan M, Sodroski J, Gabuzda D. N-linked glycosylation in the CXCR4 N-terminus inhibits binding to HIV-1 envelope glycoproteins. Virology. 324: 140-50. PMID 15183061 DOI: 10.1016/j.virol.2004.03.005  0.84
2004 Bobardt MD, Salmon P, Wang L, Esko JD, Gabuzda D, Fiala M, Trono D, Van der Schueren B, David G, Gallay PA. Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion. Journal of Virology. 78: 6567-84. PMID 15163749 DOI: 10.1128/JVI.78.12.6567-6584.2004  0.84
2004 Holm GH, Zhang C, Gorry PR, Peden K, Schols D, De Clercq E, Gabuzda D. Apoptosis of bystander T cells induced by human immunodeficiency virus type 1 with increased envelope/receptor affinity and coreceptor binding site exposure. Journal of Virology. 78: 4541-51. PMID 15078935 DOI: 10.1128/JVI.78.9.4541-4551.2004  0.84
2004 Mehle A, Strack B, Ancuta P, Zhang C, McPike M, Gabuzda D. Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 279: 7792-8. PMID 14672928 DOI: 10.1074/jbc.M313093200  0.84
2004 De Girolami U, Sharer LR, Gabuzda D, Sotrel A. Neuropathology of AIDS Aids and Other Manifestations of Hiv Infection. 773-799. DOI: 10.1016/B978-012764051-8/50030-5  0.84
2003 Ohagen A, Devitt A, Kunstman KJ, Gorry PR, Rose PP, Korber B, Taylor J, Levy R, Murphy RL, Wolinsky SM, Gabuzda D. Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS. Journal of Virology. 77: 12336-45. PMID 14581570  0.4
2003 Ancuta P, Rao R, Moses A, Mehle A, Shaw SK, Luscinskas FW, Gabuzda D. Fractalkine preferentially mediates arrest and migration of CD16+ monocytes. The Journal of Experimental Medicine. 197: 1701-7. PMID 12810688 DOI: 10.1084/jem.20022156  0.84
2002 Gorry PR, Zhang C, Wu S, Kunstman K, Trachtenberg E, Phair J, Wolinsky S, Gabuzda D. Persistence of dual-tropic HIV-1 in an individual homozygous for the CCR5 Delta 32 allele. Lancet (London, England). 359: 1832-4. PMID 12044382 DOI: 10.1016/S0140-6736(02)08681-6  0.84
2002 Gorry PR, Taylor J, Holm GH, Mehle A, Morgan T, Cayabyab M, Farzan M, Wang H, Bell JE, Kunstman K, Moore JP, Wolinsky SM, Gabuzda D. Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate. Journal of Virology. 76: 6277-92. PMID 12021361  0.84
2002 Mascola JR, Louder MK, Winter C, Prabhakara R, De Rosa SC, Douek DC, Hill BJ, Gabuzda D, Roederer M. Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells. Journal of Virology. 76: 4810-21. PMID 11967298 DOI: 10.1128/JVI.76.10.4810-4821.2002  0.84
2002 Wang J, Crawford K, Yuan M, Wang H, Gorry PR, Gabuzda D. Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophages and microglia by T helper type 2 cytokines. The Journal of Infectious Diseases. 185: 885-97. PMID 11920312 DOI: 10.1086/339522  0.84
2001 Gorry PR, Bristol G, Zack JA, Ritola K, Swanstrom R, Birch CJ, Bell JE, Bannert N, Crawford K, Wang H, Schols D, De Clercq E, Kunstman K, Wolinsky SM, Gabuzda D. Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity. Journal of Virology. 75: 10073-89. PMID 11581376 DOI: 10.1128/JVI.75.21.10073-10089.2001  0.84
2001 Ancuta P, Bakri Y, Chomont N, Hocini H, Gabuzda D, Haeffner-Cavaillon N. Opposite effects of IL-10 on the ability of dendritic cells and macrophages to replicate primary CXCR4-dependent HIV-1 strains Journal of Immunology. 166: 4244-4253. PMID 11238678  0.84
2000 Öhagen Å, Gabuzda D. Role of Vif in stability of the human immunodeficiency virus type 1 core Journal of Virology. 74: 11055-11066. PMID 11070000 DOI: 10.1128/JVI.74.23.11055-11066.2000  0.84
2000 Gabuzda D, Wang J. Chemokine receptors and mechanisms of cell death in HIV neuropathogenesis Journal of Neurovirology. 6. PMID 10871762  0.84
1999 Gabuzda D, Wang J. Chemokine receptors and virus entry in the central nervous system Journal of Neurovirology. 5: 643-658. PMID 10602405  0.84
1999 Crawford K, Gabuzda D, Pantazopoulos V, Xu J, Clement C, Reinherz E, Alper CA. Circulating CD2+ monocytes are dendritic cells Journal of Immunology. 163: 5920-5928. PMID 10570278  0.84
1999 Yang X, Chen Y, Gabuzda D. ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-κB Journal of Biological Chemistry. 274: 27981-27988. PMID 10488148 DOI: 10.1074/jbc.274.39.27981  0.84
1999 Yang X, Gabuzda D. Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway Journal of Virology. 73: 3460-3466. PMID 10074203  0.84
1998 Luo Y, Kim R, Gabuzda D, Mi S, Collins-Racie LA, Lu Z, Jacobs KA, Dorf ME. The CXC-chemokine, H174: Expression in the central nervous system Journal of Neurovirology. 4: 575-585. PMID 10065899  0.84
1998 Yang X, Gabuzda D. Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein Journal of Biological Chemistry. 273: 29879-29887. PMID 9792705 DOI: 10.1074/jbc.273.45.29879  0.84
1998 Gabuzda D, He J, Ohagen A, Vallat AV. Chemokine receptors in HIV-1 infection of the central nervous system Seminars in Immunology. 10: 203-213. PMID 9653047 DOI: 10.1006/smim.1998.0133  0.84
1998 Shi B, Raina J, Lorenzo A, Busciglio J, Gabuzda D. Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia. Journal of Neurovirology. 4: 281-90. PMID 9639071  0.84
1997 Höglund S, Öhagen Å, Goncalves J, Panganiban AT, Gabuzda D. Ultrastructure of HIV-1 genomic RNA Virology. 233: 271-279. PMID 9217051 DOI: 10.1006/viro.1997.8585  0.84
1997 He J, deCastro CM, Vandenbark GR, Busciglio J, Gabuzda D. Astrocyte apoptosis induced by HIV-1 transactivation of the c-kit protooncogene. Proceedings of the National Academy of Sciences of the United States of America. 94: 3954-9. PMID 9108086 DOI: 10.1073/pnas.94.8.3954  0.84
1997 He J, Chen Y, Farzan M, Choe H, Ohagen A, Gartner S, Busciglio J, Yang X, Hofmann W, Newman W, Mackay CR, Sodroski J, Gabuzda D. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature. 385: 645-9. PMID 9024664 DOI: 10.1038/385645a0  0.84
1996 Goncalves J, Korin Y, Zack J, Gabuzda D. Role of Vif in human immunodeficiency virus type 1 reverse transcription Journal of Virology. 70: 8701-8709. PMID 8970997  0.84
1996 Shi B, De Girolami U, He J, Wang S, Lorenzo A, Busciglio J, Gabuzda D. Apoptosis induced by HIV-1 infection of the central nervous system. The Journal of Clinical Investigation. 98: 1979-90. PMID 8903316 DOI: 10.1172/JCI119002  0.84
1996 Yang X, Goncalves J, Gabuzda D. Phosphorylation of Vif and its role in HIV-1 replication Journal of Biological Chemistry. 271: 10121-10129. PMID 8626571 DOI: 10.1074/jbc.271.17.10121  0.84
1995 Goncalves J, Shi B, Yang X, Gabuzda D. Biological activity of human immunodeficiency virus type 1 Vif requires membrane targeting by C-terminal basic domains Journal of Virology. 69: 7196-7204. PMID 7474141  0.84
1994 Goncalves J, Jallepalli P, Gabuzda DH. Subcellular localization of the Vif protein of human immunodeficiency virus type 1 Journal of Virology. 68: 704-712. PMID 8289374  0.84
1994 Clements JE, Zink MC, Narayan O, Gabuzda DH. Lentivirus infection of macrophages. Immunology Series. 60: 589-600. PMID 8251596  0.84
1994 Hoglund S, Ohagen A, Lawrence K, Gabuzda D. Role of vif during packing of the core of HIV-1 Virology. 201: 349-355. PMID 8184544 DOI: 10.1006/viro.1994.1300  0.84
1994 Gabuzda D, Busciglio J, Chen LB, Matsudaira P, Yankner BA. Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. The Journal of Biological Chemistry. 269: 13623-8. PMID 8175797  0.84
1994 Lodge R, Göttlinger H, Gabuzda D, Cohen EA, Lemay G. The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells Journal of Virology. 68: 4857-4861. PMID 8035484  0.84
1994 Gabuzda DH, Li H, Lawrence K, Vasir BS, Crawford K, Langhoff E. Essential role of vif inestablishing productive HIV-1 infection in peripheral blood T lymphocytes and monocyte/macrophages Journal of Acquired Immune Deficiency Syndromes. 7: 908-915. PMID 7519673  0.84
1993 Busciglio J, Gabuzda DH, Matsudaira P, Yankner BA. Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 2092-6. PMID 8446635  0.84
1993 Gabuzda D, Busciglio J, Yankner BA. Inhibition of beta-amyloid production by activation of protein kinase C. Journal of Neurochemistry. 61: 2326-9. PMID 8245986 DOI: 10.1111/j.1471-4159.1993.tb07479.x  0.84
1992 Gabuzda DH, Lever A, Terwilliger E, Sodroski J. Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins Journal of Virology. 66: 3306-3315. PMID 1583717  0.84
1992 Repke H, Gabuzda D, Palù G, Emmrich F, Sodroski J. Effects of CD4 synthetic peptides on HIV type I envelope glycoprotein function Journal of Immunology. 149: 1809-1816. PMID 1354681  0.84
1991 Gabuzda D, Olshevsky U, Bertani P, Haseltine WA, Sodroski J. Identification of membrane anchorage domains of the HIV-1 gpl60 envelope glycoprotein precursor Journal of Acquired Immune Deficiency Syndromes. 4: 34-40. PMID 1984054  0.84
1991 Thali M, Olshevsky U, Furman C, Gabuzda D, Li J, Sodroski J. Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity Journal of Virology. 65: 5007-5012. PMID 1870209  0.84
1991 Terwilliger EF, Langhoff E, Gabuzda D, Zazopoulos E, Haseltine WA. Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 88: 10971-10975. PMID 1720558  0.84
1991 Thali M, Olshevsky U, Furman C, Gabuzda D, Posner M, Sodroski J. Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody Journal of Virology. 65: 6188-6193. PMID 1717717  0.84
1990 Helseth E, Kowalski M, Gabuzda D, Olshevsky U, Haseltine W, Sodroski J. Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants Journal of Virology. 64: 2416-2420. PMID 2325207  0.84
1990 Helseth E, Olshevsky U, Gabuzda D, Ardman B, Haseltine W, Sodroski J. Changes in the transmembrane region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein affect membrane fusion Journal of Virology. 64: 6314-6318. PMID 2243396  0.84
1990 Gabuzda DH. Neurologic disorders associated with HIV infections Journal of the American Academy of Dermatology. 22: 1232-1236. PMID 2193951  0.84
1990 Clements JE, Gabuzda D. Cellular regulation of visna virus gene expression and its role in pathogenesis Developments in Biological Standardization. 72: 207-212. PMID 2178118  0.84
1990 Clements JE, Gabuzda DH, Gdovin SL. Cell type specific and viral regulation of visna virus gene expression Virus Research. 16: 175-183. PMID 2166980 DOI: 10.1016/0168-1702(90)90021-3  0.84
1989 Gabuzda DH, Hess JL, Small JA, Clements JE. Regulation of the visna virus long terminal repeat in macrophages involves cellular factors that bind sequences containing AP-1 sites Molecular and Cellular Biology. 9: 2728-2733. PMID 2548087 DOI: 10.1128/MCB.9.6.2728  0.84
1988 Gabuzda DH, Levy SR, Chiappa KH. Electroencephalography in AIDS and AIDS-Related Complex Clinical Eeg and Neuroscience. 19: 1-6. PMID 3396199 DOI: 10.1177/155005948801900103  0.84
1987 Gabuzda DH, Frankenburg FR. Fever caused by lithium in a patient with neuroleptic malignant syndrome Journal of Clinical Psychopharmacology. 7: 283-284. PMID 3624519  0.84
1987 Gabuzda DH, Sobel RA. HIV antigen in brains of patients with AIDS. Annals of Neurology. 22: 668. PMID 3480698 DOI: 10.1002/ana.410220524  0.84
1987 Gabuzda DH, Hirsch MS. Neurologic manifestations of infection with human immunodeficiency virus; Clinical features and pathogenesis Annals of Internal Medicine. 107: 383-391. PMID 3039890  0.84
1986 Yankner BA, Skolnik PR, Shoukimas GM, Gabuzda DH, Sobel RA, Ho DD. Cerebral granulomatous angiitis associated with isolation of human T-lymphotropic virus type III from the central nervous system. Annals of Neurology. 20: 362-4. PMID 3639720 DOI: 10.1002/ana.410200316  0.84
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