| Year |
Citation |
Score |
| 2024 |
Gastfriend BD, Snyder ME, Holt HE, Daneman R, Palecek SP, Shusta EV. Notch3 directs differentiation of brain mural cells from human pluripotent stem cell-derived neural crest. Science Advances. 10: eadi1737. PMID 38306433 DOI: 10.1126/sciadv.adi1737 |
0.344 |
|
| 2023 |
Choi ES, Shusta EV. Strategies to identify, engineer, and validate antibodies targeting blood-brain barrier receptor-mediated transcytosis systems for CNS drug delivery. Expert Opinion On Drug Delivery. 1-12. PMID 38007619 DOI: 10.1080/17425247.2023.2286371 |
0.324 |
|
| 2023 |
Foreman KL, Shusta EV, Palecek SP. Defined Differentiation of Human Pluripotent Stem Cells to Brain Microvascular Endothelial-Like Cells for Modeling the Blood-Brain Barrier. Methods in Molecular Biology (Clifton, N.J.). 2683: 113-133. PMID 37300771 DOI: 10.1007/978-1-0716-3287-1_10 |
0.366 |
|
| 2022 |
Georgieva JV, Katt M, Ye Z, Umlauf BJ, Wenthur CJ, Shusta EV. The 46.1 Antibody Mediates Neurotensin Uptake into the CNS and the Effects Depend on the Route of Intravenous Administration. Pharmaceutics. 14. PMID 36015332 DOI: 10.3390/pharmaceutics14081706 |
0.346 |
|
| 2022 |
Lajoie JM, Katt ME, Waters EA, Herrin BR, Shusta EV. Identification of lamprey variable lymphocyte receptors that target the brain vasculature. Scientific Reports. 12: 6044. PMID 35411012 DOI: 10.1038/s41598-022-09962-8 |
0.353 |
|
| 2022 |
Ye Z, Gastfriend BD, Umlauf BJ, Lynn DM, Shusta EV. Antibody-Targeted Liposomes for Enhanced Targeting of the Blood-Brain Barrier. Pharmaceutical Research. PMID 35169958 DOI: 10.1007/s11095-022-03186-1 |
0.327 |
|
| 2021 |
Ding Y, Shusta EV, Palecek SP. Integrating in vitro disease models of the neurovascular unit into discovery and development of neurotherapeutics. Current Opinion in Biomedical Engineering. 20. PMID 34693102 DOI: 10.1016/j.cobme.2021.100341 |
0.332 |
|
| 2021 |
Nishihara H, Gastfriend BD, Kasap P, Palecek SP, Shusta EV, Engelhardt B. Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions. Star Protocols. 2: 100563. PMID 34151293 DOI: 10.1016/j.xpro.2021.100563 |
0.309 |
|
| 2021 |
Gastfriend BD, Foreman KL, Katt ME, Palecek SP, Shusta EV. Integrative analysis of the human brain mural cell transcriptome. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211013700. PMID 34027687 DOI: 10.1177/0271678X211013700 |
0.321 |
|
| 2021 |
Gastfriend BD, Stebbins MJ, Du F, Shusta EV, Palecek SP. Differentiation of Brain Pericyte-Like Cells from Human Pluripotent Stem Cell-Derived Neural Crest. Current Protocols. 1: e21. PMID 33484491 DOI: 10.1002/cpz1.21 |
0.341 |
|
| 2020 |
Nishihara H, Gastfriend BD, Soldati S, Perriot S, Mathias A, Sano Y, Shimizu F, Gosselet F, Kanda T, Palecek SP, Du Pasquier R, Shusta EV, Engelhardt B. Advancing human induced pluripotent stem cell-derived blood-brain barrier models for studying immune cell interactions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 33124083 DOI: 10.1096/fj.202001507RR |
0.326 |
|
| 2020 |
Lippmann ES, Azarin SM, Palecek SP, Shusta EV. Commentary on human pluripotent stem cell-based blood-brain barrier models. Fluids and Barriers of the Cns. 17: 64. PMID 33076946 DOI: 10.1186/s12987-020-00222-3 |
0.687 |
|
| 2020 |
Georgieva JV, Goulatis LI, Stutz CC, Canfield SG, Song HW, Gastfriend BD, Shusta EV. Antibody screening using a human iPSC-based blood-brain barrier model identifies antibodies that accumulate in the CNS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 12549-12564. PMID 32960493 DOI: 10.1096/Fj.202000851R |
0.489 |
|
| 2020 |
Katt ME, Shusta EV. Models of the Blood-Brain Barrier: Building in physiological complexity. Current Opinion in Chemical Engineering. 30: 42-52. PMID 32905326 DOI: 10.1016/J.Coche.2020.07.002 |
0.383 |
|
| 2020 |
Song HW, Foreman KL, Gastfriend BD, Kuo JS, Palecek SP, Shusta EV. Transcriptomic comparison of human and mouse brain microvessels. Scientific Reports. 10: 12358. PMID 32704093 DOI: 10.1038/S41598-020-69096-7 |
0.428 |
|
| 2020 |
Umlauf BJ, Shusta EV. Site-Directed Modification of Yeast-Produced Proteins Using Expressed Protein Ligation. Methods in Molecular Biology (Clifton, N.J.). 2133: 221-233. PMID 32144670 DOI: 10.1007/978-1-0716-0434-2_11 |
0.346 |
|
| 2019 |
Lajoie JM, Cho YK, Frost D, Bremner S, Li L, Shusta EV. A yeast display immunoprecipitation screen for targeted discovery of antibodies against membrane protein complexes. Protein Engineering, Design & Selection : Peds. PMID 31769480 DOI: 10.1093/Protein/Gzz035 |
0.425 |
|
| 2019 |
Kim BJ, McDonagh MA, Deng L, Gastfriend BD, Schubert-Unkmeir A, Doran KS, Shusta EV. Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells. Fluids and Barriers of the Cns. 16: 26. PMID 31434575 DOI: 10.1186/S12987-019-0146-5 |
0.376 |
|
| 2019 |
Canfield SG, Stebbins MJ, Faubion MG, Gastfriend BD, Palecek SP, Shusta EV. An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons. Fluids and Barriers of the Cns. 16: 25. PMID 31387594 DOI: 10.1186/S12987-019-0145-6 |
0.431 |
|
| 2019 |
Kim BJ, Shusta EV, Doran KS. Past and Current Perspectives in Modeling Bacteria and Blood-Brain Barrier Interactions. Frontiers in Microbiology. 10: 1336. PMID 31263460 DOI: 10.3389/Fmicb.2019.01336 |
0.401 |
|
| 2019 |
Park TE, Mustafaoglu N, Herland A, Hasselkus R, Mannix R, FitzGerald EA, Prantil-Baun R, Watters A, Henry O, Benz M, Sanchez H, McCrea HJ, Goumnerova LC, Song HW, Palecek SP, ... Shusta E, et al. Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies. Nature Communications. 10: 2621. PMID 31197168 DOI: 10.1038/S41467-019-10588-0 |
0.479 |
|
| 2019 |
Martins Gomes SF, Westermann AJ, Sauerwein T, Hertlein T, Förstner KU, Ohlsen K, Metzger M, Shusta EV, Kim BJ, Appelt-Menzel A, Schubert-Unkmeir A. Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Infection. Frontiers in Microbiology. 10: 1181. PMID 31191497 DOI: 10.3389/Fmicb.2019.01181 |
0.417 |
|
| 2019 |
Bradley RA, Shireman J, McFalls C, Choi J, Canfield SG, Dong Y, Liu K, Lisota B, Jones JR, Petersen A, Bhattacharyya A, Palecek SP, Shusta EV, Kendziorski C, Zhang SC. Regionally specified human pluripotent stem cell-derived astrocytes exhibit different molecular signatures and functional properties. Development (Cambridge, England). PMID 31189664 DOI: 10.1242/Dev.170910 |
0.372 |
|
| 2019 |
Umlauf BJ, Clark PA, Lajoie JM, Georgieva JV, Bremner S, Herrin BR, Kuo JS, Shusta EV. Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix. Science Advances. 5: eaau4245. PMID 31106264 DOI: 10.1126/Sciadv.Aau4245 |
0.414 |
|
| 2019 |
Stebbins MJ, Gastfriend BD, Canfield SG, Lee MS, Richards D, Faubion MG, Li WJ, Daneman R, Palecek SP, Shusta EV. Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties. Science Advances. 5: eaau7375. PMID 30891496 DOI: 10.1126/Sciadv.Aau7375 |
0.346 |
|
| 2019 |
Umlauf BJ, Shusta EV. Exploiting BBB disruption for the delivery of nanocarriers to the diseased CNS. Current Opinion in Biotechnology. 60: 146-152. PMID 30849699 DOI: 10.1016/J.Copbio.2019.01.013 |
0.364 |
|
| 2019 |
Qian T, Hernday SE, Bao X, Olson WR, Panzer SE, Shusta EV, Palecek SP. Directed Differentiation of Human Pluripotent Stem Cells to Podocytes under Defined Conditions. Scientific Reports. 9: 2765. PMID 30808965 DOI: 10.1038/S41598-019-39504-8 |
0.364 |
|
| 2019 |
Umlauf B, Clark P, Lajoie J, Georgieva J, Bremner S, Herrin B, Shusta E, Kuo J. EXTH-67. IDENTIFICATION AND DEVELOPMENT OF NEURAL ECM-BINDING LAMPREY ANTIBODIES (VARIABLE LYMPHOCYTE RECEPTORS) THAT TARGET GLIOBLASTOMA Neuro-Oncology. 21: vi96-vi96. DOI: 10.1093/Neuonc/Noz175.397 |
0.398 |
|
| 2018 |
Stutz CC, Georgieva JV, Shusta EV. Coupling Brain Perfusion Screens and Next Generation Sequencing to Identify Blood-Brain Barrier Binding Antibodies. Aiche Journal. American Institute of Chemical Engineers. 64: 4229-4236. PMID 30872841 DOI: 10.1002/Aic.16360 |
0.433 |
|
| 2018 |
Goulatis LI, Ramanathan R, Shusta EV. Impacts of the -1 Amino Acid on Yeast Production of Protein-Intein Fusions. Biotechnology Progress. PMID 30341810 DOI: 10.1002/Btpr.2736 |
0.339 |
|
| 2018 |
Gastfriend BD, Palecek SP, Shusta EV. Modeling the blood-brain barrier: Beyond the endothelial cells. Current Opinion in Biomedical Engineering. 5: 6-12. PMID 29915815 DOI: 10.1016/J.Cobme.2017.11.002 |
0.446 |
|
| 2018 |
Al-Ahmad AJ, Patel R, Palecek SP, Shusta EV. Hyaluronan impairs the barrier integrity of brain microvascular endothelial cell through a CD44-dependent pathway. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18767748. PMID 29589805 DOI: 10.1177/0271678X18767748 |
0.751 |
|
| 2018 |
Clark PA, Umlauf BJ, Shusta EV, Kuo JS. Abstract 1764: Neurovascular-targeting antibodies discovered using yeast biopanning enhance drug delivery and improve survival for glioblastoma Cancer Research. 78: 1764-1764. DOI: 10.1158/1538-7445.Am2018-1764 |
0.427 |
|
| 2017 |
Zorniak M, Clark PA, Umlauf BJ, Cho Y, Shusta EV, Kuo JS. Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells. Scientific Reports. 7: 15840. PMID 29158489 DOI: 10.1038/S41598-017-16066-1 |
0.774 |
|
| 2017 |
Qian T, Maguire SE, Canfield SG, Bao X, Olson WR, Shusta EV, Palecek SP. Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells. Science Advances. 3: e1701679. PMID 29134197 DOI: 10.1126/sciadv.1701679 |
0.362 |
|
| 2017 |
Kim BJ, Bee OB, McDonagh MA, Stebbins MJ, Palecek SP, Doran KS, Shusta EV. Modeling Group B Streptococcus and Blood-Brain Barrier Interaction by Using Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells. Msphere. 2. PMID 29104935 DOI: 10.1128/mSphere.00398-17 |
0.304 |
|
| 2017 |
Stebbins MJ, Lippmann ES, Faubion MG, Daneman R, Palecek SP, Shusta EV. Activation of RARα, RARγ, or RXRα Increases Barrier Tightness in Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells. Biotechnology Journal. PMID 28960887 DOI: 10.1002/Biot.201700093 |
0.692 |
|
| 2017 |
Vatine GD, Al-Ahmad A, Barriga BK, Svendsen S, Salim A, Garcia L, Garcia VJ, Ho R, Yucer N, Qian T, Lim RG, Wu J, Thompson LM, Spivia WR, Chen Z, ... ... Shusta EV, et al. Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier. Cell Stem Cell. PMID 28526555 DOI: 10.1016/J.Stem.2017.04.002 |
0.721 |
|
| 2016 |
Goulatis LI, Shusta EV. Protein engineering approaches for regulating blood-brain barrier transcytosis. Current Opinion in Structural Biology. 45: 109-115. PMID 28040636 DOI: 10.1016/J.Sbi.2016.12.005 |
0.433 |
|
| 2016 |
Canfield SG, Stebbins MJ, Morales BS, Asai SW, Vatine GD, Svendsen CN, Palecek SP, Shusta EV. An Isogenic Blood-Brain Barrier Model Comprising Brain Endothelial Cells, Astrocytes and Neurons Derived from Human Induced Pluripotent Stem Cells. Journal of Neurochemistry. PMID 27935037 DOI: 10.1111/Jnc.13923 |
0.42 |
|
| 2016 |
Wilson HK, Faubion MG, Hjortness MK, Palecek SP, Shusta EV. Cryopreservation of brain endothelial cells derived from human induced pluripotent stem cells is enhanced by ROCK inhibition. Tissue Engineering. Part C, Methods. PMID 27846787 DOI: 10.1089/Ten.Tec.2016.0345 |
0.471 |
|
| 2016 |
Clark PA, Al-Ahmad AJ, Qian T, Zhang RR, Wilson HK, Weichert JP, Palecek SP, Kuo JS, Shusta EV. Analysis of Cancer-targeting Alkylphosphocholine Analog Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model. Molecular Pharmaceutics. PMID 27421304 DOI: 10.1021/Acs.Molpharmaceut.6B00441 |
0.75 |
|
| 2016 |
Helms HC, Abbott NJ, Burek M, Cecchelli R, Couraud PO, Deli MA, Förster C, Galla HJ, Romero IA, Shusta EV, Stebbins MJ, Vandenhaute E, Weksler B, Brodin B. In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26868179 DOI: 10.1177/0271678X16630991 |
0.43 |
|
| 2015 |
Tillotson BJ, Goulatis LI, Parenti I, Duxbury E, Shusta EV. Engineering an Anti-Transferrin Receptor ScFv for pH-Sensitive Binding Leads to Increased Intracellular Accumulation. Plos One. 10: e0145820. PMID 26713870 DOI: 10.1371/Journal.Pone.0145820 |
0.77 |
|
| 2015 |
Burns ML, Malott TM, Metcalf KJ, Puguh A, Chan JR, Shusta EV. Pro-region engineering for improved yeast display and secretion of brain derived neurotrophic factor. Biotechnology Journal. PMID 26580314 DOI: 10.1002/Biot.201500360 |
0.364 |
|
| 2015 |
Stebbins MJ, Wilson HK, Canfield SG, Qian T, Palecek SP, Shusta EV. Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells. Methods (San Diego, Calif.). PMID 26518252 DOI: 10.1016/J.Ymeth.2015.10.016 |
0.469 |
|
| 2015 |
Qian T, Shusta EV, Palecek SP. Advances in microfluidic platforms for analyzing and regulating human pluripotent stem cells. Current Opinion in Genetics & Development. 34: 54-60. PMID 26313850 DOI: 10.1016/J.Gde.2015.07.007 |
0.336 |
|
| 2015 |
Tillotson BJ, Lajoie JM, Shusta EV. Yeast Display-Based Antibody Affinity Maturation Using Detergent-Solubilized Cell Lysates. Methods in Molecular Biology (Clifton, N.J.). 1319: 65-78. PMID 26060070 DOI: 10.1007/978-1-4939-2748-7_4 |
0.797 |
|
| 2015 |
Wilson HK, Canfield SG, Hjortness MK, Palecek SP, Shusta EV. Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells. Fluids and Barriers of the Cns. 12: 13. PMID 25994964 DOI: 10.1186/S12987-015-0007-9 |
0.425 |
|
| 2015 |
Marshall CJ, Grosskopf VA, Moehling TJ, Tillotson BJ, Wiepz GJ, Abbott NL, Raines RT, Shusta EV. An evolved Mxe GyrA intein for enhanced production of fusion proteins. Acs Chemical Biology. 10: 527-38. PMID 25384269 DOI: 10.1021/Cb500689G |
0.8 |
|
| 2015 |
Lajoie JM, Shusta EV. Introducing glycophage arrays: facile production, purification and patterning of glycophages. Biotechnology Journal. 10: 20-1. PMID 25359621 DOI: 10.1002/Biot.201400591 |
0.307 |
|
| 2015 |
Lajoie JM, Shusta EV. Targeting receptor-mediated transport for delivery of biologics across the blood-brain barrier. Annual Review of Pharmacology and Toxicology. 55: 613-31. PMID 25340933 DOI: 10.1146/Annurev-Pharmtox-010814-124852 |
0.396 |
|
| 2015 |
Clark P, Al-Ahmad A, Qian T, Zhang R, Jeffery J, Wilson H, Palecek S, Weichert J, Shusta E, Kuo J. DDEL-05DIFFERENTIAL BLOOD-BRAIN BARRIER (BBB) PERMEABILITY OF ALKYLPHOSPHOCHOLINE (APC) ANALOGS ANALYZED USING AN IN VITRO PLURIPOTENT STEM CELL-DERIVED BRAIN MICROVASCULAR ENDOTHELIAL CELL SYSTEM Neuro-Oncology. 17: v74.1-v74. DOI: 10.1093/Neuonc/Nov212.05 |
0.747 |
|
| 2015 |
Lian X, Bao X, Al-Ahmad A, Liu J, Wu Y, Dong W, Dunn KK, Shusta EV, Palecek SP. Erratum: Efficient differentiation of human pluripotent stem cells to endothelial progenitors via small-molecule activation of WNT signaling (Stem Cell Reports (2014) 3 (804-816)) Stem Cell Reports. 4. DOI: 10.1016/J.Stemcr.2014.12.011 |
0.71 |
|
| 2014 |
Lian X, Bao X, Al-Ahmad A, Liu J, Wu Y, Dong W, Dunn KK, Shusta EV, Palecek SP. Efficient differentiation of human pluripotent stem cells to endothelial progenitors via small-molecule activation of WNT signaling. Stem Cell Reports. 3: 804-16. PMID 25418725 DOI: 10.1016/J.Stemcr.2014.09.005 |
0.719 |
|
| 2014 |
Wilson HK, Canfield SG, Shusta EV, Palecek SP. Concise review: tissue-specific microvascular endothelial cells derived from human pluripotent stem cells. Stem Cells (Dayton, Ohio). 32: 3037-45. PMID 25070152 DOI: 10.1002/Stem.1797 |
0.347 |
|
| 2014 |
Burns ML, Malott TM, Metcalf KJ, Hackel BJ, Chan JR, Shusta EV. Directed evolution of brain-derived neurotrophic factor for improved folding and expression in Saccharomyces cerevisiae. Applied and Environmental Microbiology. 80: 5732-42. PMID 25015885 DOI: 10.1128/Aem.01466-14 |
0.671 |
|
| 2014 |
Tan LN, Wiepz GJ, Miller DS, Shusta EV, Abbott NL. Liquid crystal droplet-based amplification of microvesicles that are shed by mammalian cells. The Analyst. 139: 2386-96. PMID 24667742 DOI: 10.1039/C3An02360E |
0.326 |
|
| 2014 |
Zhang X, Wang XX, Shusta EV. Creation and Evaluation of a Single-chain Antibody Tetramer that Targets Brain Endothelial Cells. Aiche Journal. American Institute of Chemical Engineers. 60: 1245-1252. PMID 24659822 DOI: 10.1002/Aic.14348 |
0.475 |
|
| 2014 |
Jones AR, Stutz CC, Zhou Y, Marks JD, Shusta EV. Identifying blood-brain-barrier selective single-chain antibody fragments. Biotechnology Journal. 9: 664-74. PMID 24644233 DOI: 10.1002/Biot.201300550 |
0.488 |
|
| 2014 |
Lippmann ES, Al-Ahmad A, Azarin SM, Palecek SP, Shusta EV. A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources. Scientific Reports. 4: 4160. PMID 24561821 DOI: 10.1038/Srep04160 |
0.805 |
|
| 2014 |
Malin D, Strekalova E, Petrovic V, Deal AM, Al Ahmad A, Adamo B, Miller CR, Ugolkov A, Livasy C, Fritchie K, Hamilton E, Blackwell K, Geradts J, Ewend M, Carey L, ... Shusta EV, et al. αB-crystallin: a novel regulator of breast cancer metastasis to the brain. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 56-67. PMID 24132917 DOI: 10.1158/1078-0432.Ccr-13-1255 |
0.35 |
|
| 2014 |
Stutz CC, Zhang X, Shusta EV. Combinatorial approaches for the identification of brain drug delivery targets. Current Pharmaceutical Design. 20: 1564-76. PMID 23789958 DOI: 10.2174/13816128113199990459 |
0.439 |
|
| 2013 |
Marshall CJ, Agarwal N, Kalia J, Grosskopf VA, McGrath NA, Abbott NL, Raines RT, Shusta EV. Facile chemical functionalization of proteins through intein-linked yeast display. Bioconjugate Chemistry. 24: 1634-44. PMID 23924245 DOI: 10.1021/Bc4002618 |
0.361 |
|
| 2013 |
Lippmann ES, Al-Ahmad A, Palecek SP, Shusta EV. Modeling the blood-brain barrier using stem cell sources. Fluids and Barriers of the Cns. 10: 2. PMID 23305164 DOI: 10.1186/2045-8118-10-2 |
0.81 |
|
| 2013 |
Tillotson BJ, de Larrinoa IF, Skinner CA, Klavas DM, Shusta EV. Antibody affinity maturation using yeast display with detergent-solubilized membrane proteins as antigen sources. Protein Engineering, Design & Selection : Peds. 26: 101-12. PMID 23109730 DOI: 10.1093/Protein/Gzs077 |
0.806 |
|
| 2013 |
Tillotson BJ, Cho YK, Shusta EV. Cells and cell lysates: a direct approach for engineering antibodies against membrane proteins using yeast surface display. Methods (San Diego, Calif.). 60: 27-37. PMID 22449570 DOI: 10.1016/J.Ymeth.2012.03.010 |
0.794 |
|
| 2012 |
Pavoor TV, Wheasler JA, Kamat V, Shusta EV. An enhanced approach for engineering thermally stable proteins using yeast display. Protein Engineering, Design & Selection : Peds. 25: 625-30. PMID 22767886 DOI: 10.1093/Protein/Gzs041 |
0.756 |
|
| 2012 |
Lippmann ES, Azarin SM, Kay JE, Nessler RA, Wilson HK, Al-Ahmad A, Palecek SP, Shusta EV. Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells. Nature Biotechnology. 30: 783-91. PMID 22729031 DOI: 10.1038/Nbt.2247 |
0.808 |
|
| 2011 |
Lippmann ES, Weidenfeller C, Svendsen CN, Shusta EV. Blood-brain barrier modeling with co-cultured neural progenitor cell-derived astrocytes and neurons. Journal of Neurochemistry. 119: 507-20. PMID 21854389 DOI: 10.1111/J.1471-4159.2011.07434.X |
0.696 |
|
| 2011 |
Shayan G, Choi YS, Shusta EV, Shuler ML, Lee KH. Murine in vitro model of the blood-brain barrier for evaluating drug transport. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 42: 148-55. PMID 21078386 DOI: 10.1016/J.Ejps.2010.11.005 |
0.429 |
|
| 2010 |
Cho YK, Shusta EV. Antibody library screens using detergent-solubilized mammalian cell lysates as antigen sources. Protein Engineering, Design & Selection : Peds. 23: 567-77. PMID 20498037 DOI: 10.1093/Protein/Gzq029 |
0.43 |
|
| 2010 |
Agarwal N, Lippmann ES, Shusta EV. Identification and expression profiling of blood-brain barrier membrane proteins. Journal of Neurochemistry. 112: 625-35. PMID 19895664 DOI: 10.1111/J.1471-4159.2009.06481.X |
0.703 |
|
| 2009 |
Pavoor TV, Cho YK, Shusta EV. Development of GFP-based biosensors possessing the binding properties of antibodies. Proceedings of the National Academy of Sciences of the United States of America. 106: 11895-900. PMID 19574456 DOI: 10.1073/Pnas.0902828106 |
0.762 |
|
| 2009 |
Agarwal N, Shusta EV. Multiplex expression cloning of blood-brain barrier membrane proteins. Proteomics. 9: 1099-108. PMID 19180536 DOI: 10.1002/Pmic.200800368 |
0.434 |
|
| 2009 |
Cho YK, Chen I, Wei X, Li L, Shusta EV. A yeast display immunoprecipitation method for efficient isolation and characterization of antigens. Journal of Immunological Methods. 341: 117-26. PMID 19041873 DOI: 10.1016/J.Jim.2008.11.005 |
0.407 |
|
| 2009 |
Jones AR, Shusta EV. Antibodies and the Blood-Brain Barrier Therapeutic Monoclonal Antibodies: From Bench to Clinic. 483-502. DOI: 10.1002/9780470485408.ch21 |
0.325 |
|
| 2008 |
Huang D, Gore PR, Shusta EV. Increasing yeast secretion of heterologous proteins by regulating expression rates and post-secretory loss. Biotechnology and Bioengineering. 101: 1264-75. PMID 18781684 DOI: 10.1002/Bit.22019 |
0.507 |
|
| 2008 |
Wentz AE, Shusta EV. Enhanced secretion of heterologous proteins from yeast by overexpression of ribosomal subunit RPP0. Biotechnology Progress. 24: 748-56. PMID 18396911 DOI: 10.1021/Bp070345M |
0.789 |
|
| 2008 |
Pepper LR, Cho YK, Boder ET, Shusta EV. A decade of yeast surface display technology: where are we now? Combinatorial Chemistry & High Throughput Screening. 11: 127-34. PMID 18336206 DOI: 10.2174/138620708783744516 |
0.331 |
|
| 2008 |
Calabria AR, Shusta EV. A genomic comparison of in vivo and in vitro brain microvascular endothelial cells. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 135-48. PMID 17565361 DOI: 10.1038/Sj.Jcbfm.9600518 |
0.779 |
|
| 2007 |
Jones AR, Shusta EV. Blood-brain barrier transport of therapeutics via receptor-mediation. Pharmaceutical Research. 24: 1759-71. PMID 17619996 DOI: 10.1007/S11095-007-9379-0 |
0.395 |
|
| 2007 |
Weidenfeller C, Svendsen CN, Shusta EV. Differentiating embryonic neural progenitor cells induce blood-brain barrier properties. Journal of Neurochemistry. 101: 555-65. PMID 17254017 DOI: 10.1111/J.1471-4159.2006.04394.X |
0.453 |
|
| 2007 |
Wang XX, Cho YK, Shusta EV. Mining a yeast library for brain endothelial cell-binding antibodies. Nature Methods. 4: 143-5. PMID 17206151 DOI: 10.1038/Nmeth993 |
0.451 |
|
| 2007 |
Wentz AE, Shusta EV. A novel high-throughput screen reveals yeast genes that increase secretion of heterologous proteins. Applied and Environmental Microbiology. 73: 1189-98. PMID 17189442 DOI: 10.1128/Aem.02427-06 |
0.792 |
|
| 2006 |
Huang D, Shusta EV. A yeast platform for the production of single-chain antibody-green fluorescent protein fusions. Applied and Environmental Microbiology. 72: 7748-59. PMID 17028228 DOI: 10.1128/Aem.01403-06 |
0.551 |
|
| 2006 |
Calabria AR, Shusta EV. Blood-brain barrier genomics and proteomics: elucidating phenotype, identifying disease targets and enabling brain drug delivery. Drug Discovery Today. 11: 792-9. PMID 16935746 DOI: 10.1016/J.Drudis.2006.07.006 |
0.768 |
|
| 2006 |
Calabria AR, Weidenfeller C, Jones AR, de Vries HE, Shusta EV. Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction. Journal of Neurochemistry. 97: 922-33. PMID 16573646 DOI: 10.1111/J.1471-4159.2006.03793.X |
0.767 |
|
| 2006 |
Hackel BJ, Huang D, Bubolz JC, Wang XX, Shusta EV. Production of soluble and active transferrin receptor-targeting single-chain antibody using Saccharomyces cerevisiae. Pharmaceutical Research. 23: 790-7. PMID 16550469 DOI: 10.1007/S11095-006-9778-7 |
0.698 |
|
| 2005 |
Wang XX, Shusta EV. The use of scFv-displaying yeast in mammalian cell surface selections. Journal of Immunological Methods. 304: 30-42. PMID 16099466 DOI: 10.1016/J.Jim.2005.05.006 |
0.351 |
|
| 2005 |
Huang D, Shusta EV. Secretion and surface display of green fluorescent protein using the yeast Saccharomyces cerevisiae. Biotechnology Progress. 21: 349-57. PMID 15801770 DOI: 10.1021/Bp0497482 |
0.544 |
|
| 2005 |
Shusta EV. Blood-brain barrier genomics, proteomics, and new transporter discovery. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 2: 151-61. PMID 15717066 DOI: 10.1602/Neurorx.2.1.151 |
0.419 |
|
| 2003 |
Shusta EV, Li JY, Boado RJ, Pardridge WM. The Ro52/SS-A autoantigen has elevated expression at the brain microvasculature. Neuroreport. 14: 1861-5. PMID 14534436 DOI: 10.1097/00001756-200310060-00021 |
0.659 |
|
| 2002 |
Shusta EV, Zhu C, Boado RJ, Pardridge WM. Subtractive expression cloning reveals high expression of CD46 at the blood-brain barrier. Journal of Neuropathology and Experimental Neurology. 61: 597-604. PMID 12125738 DOI: 10.1093/Jnen/61.7.597 |
0.628 |
|
| 2002 |
Shusta EV, Boado RJ, Pardridge WM. Vascular proteomics and subtractive antibody expression cloning. Molecular & Cellular Proteomics : McP. 1: 75-82. PMID 12096143 DOI: 10.1074/Mcp.T100008-Mcp200 |
0.641 |
|
| 2002 |
Shusta EV, Boado RJ, Mathern GW, Pardridge WM. Vascular genomics of the human brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 245-52. PMID 11891429 DOI: 10.1097/00004647-200203000-00001 |
0.637 |
|
| 2001 |
Kieke MC, Sundberg E, Shusta EV, Mariuzza RA, Wittrup KD, Kranz DM. High affinity T cell receptors from yeast display libraries block T cell activation by superantigens. Journal of Molecular Biology. 307: 1305-15. PMID 11292343 DOI: 10.1006/Jmbi.2001.4560 |
0.585 |
|
| 2000 |
Shusta EV, Holler PD, Kieke MC, Kranz DM, Wittrup KD. Directed evolution of a stable scaffold for T-cell receptor engineering. Nature Biotechnology. 18: 754-9. PMID 10888844 DOI: 10.1038/77325 |
0.605 |
|
| 2000 |
Holler PD, Holman PO, Shusta EV, O'Herrin S, Wittrup KD, Kranz DM. In vitro evolution of a T cell receptor with high affinity for peptide/MHC. Proceedings of the National Academy of Sciences of the United States of America. 97: 5387-92. PMID 10779548 DOI: 10.1073/Pnas.080078297 |
0.556 |
|
| 1999 |
Shusta EV, Kieke MC, Parke E, Kranz DM, Wittrup KD. Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency. Journal of Molecular Biology. 292: 949-56. PMID 10512694 DOI: 10.1006/Jmbi.1999.3130 |
0.562 |
|
| 1999 |
Kieke MC, Shusta EV, Boder ET, Teyton L, Wittrup KD, Kranz DM. Selection of functional T cell receptor mutants from a yeast surface-display library. Proceedings of the National Academy of Sciences of the United States of America. 96: 5651-6. PMID 10318939 DOI: 10.1073/Pnas.96.10.5651 |
0.589 |
|
| 1999 |
Shusta EV, Vanantwerp J, Wittrup KD. Biosynthetic polypeptide libraries Current Opinion in Biotechnology. 10: 117-122. PMID 10209135 DOI: 10.1016/S0958-1669(99)80020-2 |
0.441 |
|
| 1998 |
Shusta EV, Raines RT, Plückthun A, Wittrup KD. Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments Nature Biotechnology. 16: 773-777. PMID 9702778 DOI: 10.1038/nbt0898-773 |
0.528 |
|
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