Aldons J. Lusis - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Immunology, Microbiology Biology

468 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Civelek M, Fogelman AM, Hedrick CC, Lusis AJ, Romanoski CE, Witztum JL. In memoriam: Judith A. Berliner, Ph.D. Journal of Lipid Research. 63: 100180. PMID 35298953 DOI: 10.1016/j.jlr.2022.100180  0.7
2022 Li L, Chen Z, von Scheidt M, Li S, Steiner A, Güldener U, Koplev S, Ma A, Hao K, Pan C, Lusis AJ, Pang S, Kessler T, Ermel R, Sukhavasi K, et al. Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes. Basic Research in Cardiology. 117: 6. PMID 35175464 DOI: 10.1007/s00395-022-00917-8  0.319
2021 Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, Mouisel E, Pan C, Moore TM, Péterfy M, Romanoski CE, Reue K, Björkegren JLM, Laakso M, Liesa M, ... Lusis AJ, et al. Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2. Nature Metabolism. PMID 34697471 DOI: 10.1038/s42255-021-00481-w  0.684
2021 von Scheidt M, Zhao Y, de Aguiar Vallim TQ, Che N, Wierer M, Seldin MM, Franzén O, Kurt Z, Pang S, Bongiovanni D, Yamamoto M, Edwards PA, Ruusalepp A, Kovacic JC, Mann M, ... ... Lusis AJ, et al. The Transcription Factor MAFF Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism. Circulation. PMID 33626882 DOI: 10.1161/CIRCULATIONAHA.120.050186  0.317
2021 Selvarajan I, Toropainen A, Garske KM, López Rodríguez M, Ko A, Miao Z, Kaminska D, Õunap K, Örd T, Ravindran A, Liu OH, Moreau PR, Jawahar Deen A, Männistö V, Pan C, ... ... Lusis AJ, et al. Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease. American Journal of Human Genetics. PMID 33626337 DOI: 10.1016/j.ajhg.2021.02.006  0.709
2021 Hartiala JA, Han Y, Jia Q, Hilser JR, Huang P, Gukasyan J, Schwartzman WS, Cai Z, Biswas S, Trégouët DA, Smith NL, Seldin M, ... ... Lusis AJ, et al. Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. European Heart Journal. PMID 33532862 DOI: 10.1093/eurheartj/ehaa1040  0.654
2020 Rau CD, Gonzales NM, Bloom JS, Park D, Ayroles J, Palmer AA, Lusis AJ, Zaitlen N. Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for "polygenic epistasis". Plos Genetics. 16: e1009165. PMID 33104702 DOI: 10.1371/journal.pgen.1009165  0.626
2020 Krishnan KC, Floyd RR, Sabir S, Jayasekera DW, Leon-Mimila PV, Jones AE, Cortez AA, Shravah V, Péterfy M, Stiles L, Canizales-Quinteros S, Divakaruni AS, Huertas-Vazquez A, Lusis AJ. Liver Pyruvate Kinase Promotes NAFLD/NASH in both Mice and Humans in a Sex-Specific Manner. Cellular and Molecular Gastroenterology and Hepatology. PMID 32942044 DOI: 10.1016/J.Jcmgh.2020.09.004  0.361
2020 Tuominen I, Fuqua BK, Pan C, Renaud N, Wroblewski K, Civelek M, Clerkin K, Asaryan A, Haroutunian SG, Loureiro J, Borawski J, Roma G, Knehr J, Carbone W, French S, ... ... Lusis AJ, et al. The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice. Cellular and Molecular Gastroenterology and Hepatology. PMID 32866618 DOI: 10.1016/J.Jcmgh.2020.08.010  0.352
2020 Ahn IS, Lang JM, Olson CA, Diamante G, Zhang G, Ying Z, Byun HR, Cely I, Ding J, Cohn P, Kurtz I, Gomez-Pinilla F, Lusis AJ, Hsiao EY, Yang X. Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to Fructose Consumption in Mice. The Journal of Nutrition. PMID 32856048 DOI: 10.1093/Jn/Nxaa239  0.361
2020 Zhou Z, Moore TM, Drew BG, Ribas V, Wanagat J, Civelek M, Segawa M, Wolf DM, Norheim F, Seldin MM, Strumwasser AR, Whitney KA, Lester E, Reddish BR, Vergnes L, ... ... Lusis AJ, et al. Estrogen receptor α controls metabolism in white and brown adipocytes by regulating and mitochondrial remodeling. Science Translational Medicine. 12. PMID 32759275 DOI: 10.1126/Scitranslmed.Aax8096  0.338
2020 Rau CD, Lusis AJ, Wang Y. Systems Genetics for Mechanistic Discovery in Heart Diseases. Circulation Research. 126: 1795-1815. PMID 32496909 DOI: 10.1161/Circresaha.119.315863  0.654
2020 Korshunov VA, Smolock EM, Wines-Samuelson ME, Faiyaz A, Mickelsen DM, Quinn B, Pan C, Dugbartey GJ, Yan C, Doyley MM, Lusis AJ, Berk BC. Natriuretic Peptide Receptor 2 Locus Contributes to Carotid Remodeling. Journal of the American Heart Association. e014257. PMID 32394795 DOI: 10.1161/Jaha.119.014257  0.397
2020 Suh JS, Lee SH, Fouladian Z, Lee JY, Kim T, Kang MK, Lusis AJ, Boström KI, Kim RH, Park NH. Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model. Scientific Reports. 10: 6383. PMID 32286430 DOI: 10.1038/S41598-020-63350-8  0.331
2020 Fathzadeh M, Li J, Rao A, Cook N, Chennamsetty I, Seldin M, Zhou X, Sangwung P, Gloudemans MJ, Keller M, Attie A, Yang J, Wabitsch M, Carcamo-Orive I, Tada Y, ... Lusis AJ, et al. FAM13A affects body fat distribution and adipocyte function. Nature Communications. 11: 1465. PMID 32193374 DOI: 10.1038/S41467-020-15291-Z  0.375
2020 Zhang Z, Feng AC, Salisbury D, Liu X, Wu X, Kim J, Lapina I, Wang D, Lee B, Fraga J, Pan C, Williams KJ, Lusis AJ, Scumpia P, Sallam T. Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice. Nature Communications. 11: 984. PMID 32080181 DOI: 10.1038/S41467-020-14711-4  0.356
2019 Edillor CR, Parks BW, Mehrabian M, Lusis AJ, Pellegrini M. DNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains. Frontiers in Endocrinology. 10: 882. PMID 31920990 DOI: 10.3389/Fendo.2019.00882  0.324
2019 Maazi H, Hartiala JA, Suzuki Y, Crow AL, Shafiei Jahani P, Lam J, Patel N, Rigas D, Han Y, Huang P, Eskin E, Lusis AJ, Gilliland FD, Akbari O, Allayee H. A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity. Plos Genetics. 15: e1008528. PMID 31869344 DOI: 10.1371/Journal.Pgen.1008528  0.394
2019 Chella Krishnan K, Sabir S, Shum M, Meng Y, Acín-Pérez R, Lang JM, Floyd RR, Vergnes L, Seldin MM, Fuqua BK, Jayasekera DW, Nand SK, Anum DC, Pan C, Stiles L, ... ... Lusis AJ, et al. Sex-specific metabolic functions of adipose Lipocalin-2. Molecular Metabolism. 30: 30-47. PMID 31767179 DOI: 10.1016/J.Molmet.2019.09.009  0.32
2019 Wu Y, Broadaway KA, Raulerson CK, Scott LJ, Pan C, Ko A, He A, Tilford C, Fuchsberger C, Locke AE, Stringham HM, Jackson AU, Narisu N, Kuusisto J, Pajukanta P, ... ... Lusis AJ, et al. Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution. Human Molecular Genetics. PMID 31691812 DOI: 10.1093/Hmg/Ddz263  0.315
2019 Lusis AJ. Y-Chromosome Genetic Variation Associated With Atherosclerosis and Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 2201-2202. PMID 31644351 DOI: 10.1161/Atvbaha.119.313369  0.362
2019 Helsley RN, Venkateshwari V, Brown AL, Gromovsky AD, Schugar RC, Ramachandiran I, Fung K, Kabbany MN, Banerjee R, Neumann CK, Finney C, Pathak P, Danny O, Osborn LJ, Massey W, ... ... Lusis AJ, et al. Obesity-linked suppression of membrane-bound -Acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease. Elife. 8. PMID 31621579 DOI: 10.7554/Elife.49882  0.312
2019 Bhetraratana M, Orozco LD, Hong J, Diamante G, Majid S, Bennett BJ, Ahn IS, Yang X, Lusis AJ, Araujo JA. Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies. Archives of Biochemistry and Biophysics. 108116. PMID 31568751 DOI: 10.1016/J.Abb.2019.108116  0.794
2019 Raulerson CK, Ko A, Kidd JC, Currin KW, Brotman SM, Cannon ME, Wu Y, Spracklen CN, Jackson AU, Stringham HM, Welch RP, Fuchsberger C, Locke AE, Narisu N, Lusis AJ, et al. Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits. American Journal of Human Genetics. PMID 31564431 DOI: 10.1016/J.Ajhg.2019.09.001  0.422
2019 Wang J, Huertas-Vazquez A, Wang Y, Lusis AJ. Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis. Frontiers in Cardiovascular Medicine. 6: 100. PMID 31417910 DOI: 10.3389/Fcvm.2019.00100  0.408
2019 Xiong X, Kuang H, Ansari S, Liu T, Gong J, Wang S, Zhao XY, Ji Y, Li C, Guo L, Zhou L, Chen Z, Leon-Mimila P, Chung MT, Kurabayashi K, ... ... Lusis AJ, et al. Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis. Molecular Cell. 75: 644-660.e5. PMID 31398325 DOI: 10.1016/J.Molcel.2019.07.028  0.31
2019 Yin F, Gupta R, Vergnes L, Driscoll WS, Ricks J, Ramanathan G, Stewart JA, Shih DM, Faull KF, Beaven SW, Lusis AJ, Reue K, Rosenfeld ME, Araujo JA. Diesel Exhaust Induces Mitochondrial Dysfunction, Hyperlipidemia and Liver Steatosis. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119312736. PMID 31340670 DOI: 10.1161/Atvbaha.119.312736  0.601
2019 Cordero P, Parikh VN, Chin ET, Erbilgin A, Gloudemans MJ, Shang C, Huang Y, Chang AC, Smith KS, Dewey F, Zaleta K, Morley M, Brandimarto J, Glazer N, Waggott D, ... ... Lusis AJ, et al. Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure. Nature Communications. 10: 2760. PMID 31235787 DOI: 10.1038/S41467-019-10591-5  0.798
2019 AlSiraj Y, Chen X, Thatcher SE, Temel RE, Cai L, Blalock E, Katz W, Ali HM, Petriello M, Deng P, Morris AJ, Wang X, Lusis AJ, Arnold AP, Reue K, et al. XX sex chromosome complement promotes atherosclerosis in mice. Nature Communications. 10: 2631. PMID 31201301 DOI: 10.1038/S41467-019-10462-Z  0.338
2019 Zeng L, Talukdar HA, Koplev S, Giannarelli C, Ivert T, Gan LM, Ruusalepp A, Schadt EE, Kovacic JC, Lusis AJ, Michoel T, Schunkert H, Björkegren JLM. Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease. Journal of the American College of Cardiology. 73: 2946-2957. PMID 31196451 DOI: 10.1016/J.Jacc.2019.03.520  0.345
2019 Zhou M, Jing S, Wu CY, Shu L, Dong W, Liu Y, Chen M, Wynn RM, Wang J, Wang J, Gui WJ, Qi X, Lusis AJ, Li Z, Wang W, et al. Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance. Diabetes. PMID 31167878 DOI: 10.2337/Db18-0927  0.366
2019 Shih DM, Zhu W, Schugar RC, Meng Y, Jia X, Miikeda A, Wang Z, Zieger M, Lee R, Graham M, Allayee H, Cantor RM, Mueller C, Brown JM, Hazen SL, ... Lusis AJ, et al. Genetic Deficiency of Flavin-Containing Monooxygenase-3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119312592. PMID 31070450 DOI: 10.1161/Atvbaha.119.312592  0.366
2019 Geoghegan G, Simcox J, Seldin MM, Parnell TJ, Stubben C, Just S, Begaye L, Lusis AJ, Villanueva CJ. Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism. Molecular Metabolism. PMID 30948248 DOI: 10.1016/J.Molmet.2019.03.003  0.319
2019 Parker BL, Calkin AC, Seldin MM, Keating MF, Tarling EJ, Yang P, Moody SC, Liu Y, Zerenturk EJ, Needham EJ, Miller ML, Clifford BL, Morand P, Watt MJ, Meex RCR, ... ... Lusis AJ, et al. An integrative systems genetic analysis of mammalian lipid metabolism. Nature. PMID 30814737 DOI: 10.1038/S41586-019-0984-Y  0.356
2019 Shih DM, Meng Y, Sallam T, Vergnes L, Shu ML, Reue K, Tontonoz P, Fogelman AM, Lusis AJ, Reddy ST. PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. Antioxidants (Basel, Switzerland). 8. PMID 30641857 DOI: 10.3390/Antiox8010019  0.355
2019 Norheim F, Hasin-Brumshtein Y, Vergnes L, Chella Krishnan K, Pan C, Seldin MM, Hui ST, Mehrabian M, Zhou Z, Gupta S, Parks BW, Walch A, Reue K, Hofmann SM, Arnold AP, ... Lusis AJ, et al. Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits. Cell Metabolism. PMID 30639359 DOI: 10.1016/J.Cmet.2018.12.013  0.406
2019 Pamir N, Pan C, Plubell DL, Hutchins PM, Tang C, Wimberger J, Irwin A, Vallim TQA, Heinecke JW, Lusis AJ. Genetic control of the mouse HDL proteome defines HDL traits, function, and heterogeneity. Journal of Lipid Research. PMID 30622162 DOI: 10.1194/Jlr.M090555  0.382
2018 Org E, Lusis AJ. Using the natural variation of mouse populations to understand host-gut microbiome interactions. Drug Discovery Today. Disease Models. 28: 61-71. PMID 32831858 DOI: 10.1016/J.Ddmod.2019.08.003  0.329
2018 Kasahara K, Krautkramer KA, Org E, Romano KA, Kerby RL, Vivas EI, Mehrabian M, Denu JM, Bäckhed F, Lusis AJ, Rey FE. Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model. Nature Microbiology. PMID 30397344 DOI: 10.1038/S41564-018-0272-X  0.355
2018 Pirie E, Ray S, Pan C, Fu W, Powers AF, Polikoff D, Miller CM, Kudrna KM, Harris EN, Lusis AJ, Crooke RM, Lee RG. Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1. Plos Genetics. 14: e1007732. PMID 30372444 DOI: 10.1371/Journal.Pgen.1007732  0.452
2018 Kurt Z, Barrere-Cain R, LaGuardia J, Mehrabian M, Pan C, Hui ST, Norheim F, Zhou Z, Hasin Y, Lusis AJ, Yang X. Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease. Biology of Sex Differences. 9: 46. PMID 30343673 DOI: 10.1186/S13293-018-0205-7  0.301
2018 Lin LY, Chun-Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, ... ... Lusis AJ, et al. Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure. G3 (Bethesda, Md.). PMID 30201759 DOI: 10.1534/G3.118.200655  0.652
2018 Chella Krishnan K, Mehrabian M, Lusis AJ. Sex differences in metabolism and cardiometabolic disorders. Current Opinion in Lipidology. 29: 404-410. PMID 30156571 DOI: 10.1097/Mol.0000000000000536  0.325
2018 Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, et al. Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nature Communications. 9: 3472. PMID 30135520 DOI: 10.1038/S41467-018-05849-3  0.334
2018 Erbilgin A, Seldin MM, Wu X, Mehrabian M, Zhou Z, Qi H, Dabirian KS, Sevag Packard RR, Hsieh W, Bensinger SJ, Sinha S, Lusis AJ. Transcription Factor Deficiency Reduces Atherosclerosis and Promotes Macrophage Apoptosis in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 30026271 DOI: 10.1161/Atvbaha.118.311266  0.796
2018 Park S, Ranjbarvazirj S, Lay FD, Zhao P, Miller MJ, Dhaliwal JS, Huertas-Vazquez A, Wu X, Qiao R, Soffer JM, Mikkola HKA, Lusis AJ, Ardehali R. Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. Circulation. PMID 29950403 DOI: 10.1161/Circulationaha.118.035420  0.379
2018 Hui ST, Kurt Z, Tuominen I, Norheim F, Davis RC, Pan C, Dirks DL, Magyar CE, French SW, Chella Krishnan K, Sabir S, Campos-Pérez F, Méndez-Sánchez N, Macías-Kauffer L, León-Mimila P, ... ... Lusis AJ, et al. The Genetic Architecture of Diet-induced Hepatic Fibrosis in Mice. Hepatology (Baltimore, Md.). PMID 29907965 DOI: 10.1002/Hep.30113  0.406
2018 Hitzel J, Lee E, Zhang Y, Bibli SI, Li X, Zukunft S, Pflüger B, Hu J, Schürmann C, Vasconez AE, Oo JA, Kratzer A, Kumar S, Rezende F, Josipovic I, ... ... Lusis AJ, et al. Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Nature Communications. 9: 2292. PMID 29895827 DOI: 10.1038/S41467-018-04602-0  0.686
2018 Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, ... ... Lusis AJ, et al. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics. PMID 29893869 DOI: 10.1093/Hmg/Ddy205  0.664
2018 Norheim F, Bjellaas T, Hui ST, Chella Krishnan K, Lee J, Gupta S, Pan C, Hasin-Brumshtein Y, Parks BW, Li D, Bui H, Mosier M, Wu Y, Huertas-Vazquez A, Hazen SW, ... ... Lusis AJ, et al. Genetic, dietary, and sex-specific regulation of hepatic ceramides and relationship between hepatic ceramides and insulin resistance. Journal of Lipid Research. PMID 29739864 DOI: 10.1194/Jlr.M081398  0.333
2018 Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, et al. Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nature Communications. 9: 1512. PMID 29666371 DOI: 10.1038/S41467-018-03554-9  0.408
2018 Hiyari S, Green E, Pan C, Lari S, Davar M, Davis R, Camargo PM, Tetradis S, Lusis AJ, Pirih FQ. Genome-Wide Association Study Identifies Cxcl Family Members as Partial Mediators of LPS-induced Periodontitis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29637625 DOI: 10.1002/Jbmr.3440  0.336
2018 Small KS, Todorčević M, Civelek M, El-Sayed Moustafa JS, Wang X, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, ... ... Lusis AJ, et al. Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. Nature Genetics. 50: 572-580. PMID 29632379 DOI: 10.1038/S41588-018-0088-X  0.33
2018 Orozco LD, Farrell C, Hale C, Rbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, ... Lusis AJ, et al. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics. PMID 29566149 DOI: 10.1093/Hmg/Ddy093  0.705
2018 Santolini M, Romay MC, Yukhtman CL, Rau CD, Ren S, Saucerman JJ, Wang JJ, Weiss JN, Wang Y, Lusis AJ, Karma A. A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure. Npj Systems Biology and Applications. 4: 12. PMID 29507758 DOI: 10.1038/s41540-018-0046-3  0.647
2018 Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, ... ... Lusis AJ, et al. Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. Nature Medicine. PMID 29431742 DOI: 10.1038/Nm.4479  0.383
2018 Chella Krishnan K, Kurt Z, Barrere-Cain R, Sabir S, Das A, Floyd R, Vergnes L, Zhao Y, Che N, Charugundla S, Qi H, Zhou Z, Meng Y, Pan C, Seldin MM, ... ... Lusis AJ, et al. Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease. Cell Systems. PMID 29361464 DOI: 10.1016/J.Cels.2017.12.006  0.34
2018 AHN IS, LANG J, YING Z, BYUN HR, ZHANG G, OLSON C, HSAIO E, LUSIS A, GOMEZ-PINILLA F, YANG X. Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to High Fructose Consumption in Mice Diabetes. 67: 290-LB. DOI: 10.2337/Db18-290-Lb  0.358
2018 KRISHNAN KC, SABIR S, FLOYD R, JAYASEKERA D, LUSIS A. Sex-Specific Role of Adipose-Derived Lipocalin-2 in Diet-Induced Obesity and Insulin Resistance Diabetes. 67: 285-LB. DOI: 10.2337/Db18-285-Lb  0.326
2018 Rau CD, Wang J, Ohearn J, Avetisyan R, Lusis AJ, Wang Y. Abstract 372: Master Transcriptional Regulators of Cardiac Gene Expression in Heart Failure Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.372  0.601
2017 Shu L, Chan KHK, Zhang G, Huan T, Kurt Z, Zhao Y, Codoni V, Trégouët DA, Yang J, Wilson JG, Luo X, Levy D, Lusis AJ, Liu S, et al. Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States. Plos Genetics. 13: e1007040. PMID 28957322 DOI: 10.1371/Journal.Pgen.1007040  0.401
2017 Patterson M, Barske L, Van Handel B, Rau CD, Gan P, Sharma A, Parikh S, Denholtz M, Huang Y, Yamaguchi Y, Shen H, Allayee H, Crump JG, Force TI, Lien CL, ... ... Lusis AJ, et al. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nature Genetics. PMID 28783163 DOI: 10.1038/Ng.3929  0.609
2017 Cannon ME, Duan Q, Wu Y, Zeynalzadeh M, Xu Z, Kangas AJ, Soininen P, Ala-Korpela M, Civelek M, Lusis AJ, Kuusisto J, Collins FS, Boehnke M, Tang H, Laakso M, et al. Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus. G3 (Bethesda, Md.). PMID 28754724 DOI: 10.1534/G3.117.300088  0.351
2017 Buscher K, Ehinger E, Gupta P, Pramod AB, Wolf D, Tweet G, Pan C, Mills CD, Lusis AJ, Ley K. Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival. Nature Communications. 8: 16041. PMID 28737175 DOI: 10.1038/Ncomms16041  0.362
2017 Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng Y, ... ... Lusis AJ, et al. The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. Cell Reports. 19: 2451-2461. PMID 28636934 DOI: 10.1016/J.Celrep.2017.05.077  0.328
2017 Kessler T, Wobst J, Wolf B, Eckhold J, Vilne B, Hollstein R, von Ameln S, Dang TA, Sager HB, Rumpf PM, Aherrahrou R, Kastrati A, Bjoerkegren JLM, Erdmann J, Lusis AJ, et al. Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus. Circulation. PMID 28487391 DOI: 10.1161/Circulationaha.116.024152  0.342
2017 Civelek M, Wu Y, Pan C, Raulerson CK, Ko A, He A, Tilford C, Saleem NK, Stančáková A, Scott LJ, Fuchsberger C, Stringham HM, Jackson AU, Narisu N, Chines PS, ... ... Lusis AJ, et al. Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits. American Journal of Human Genetics. 100: 428-443. PMID 28257690 DOI: 10.1016/J.Ajhg.2017.01.027  0.463
2017 Seldin MM, Kim ED, Romay MC, Li S, Rau CD, Wang JJ, Chella Krishnan K, Wang Y, Deb A, Lusis AJ. Systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00068.2016. PMID 28235788 DOI: 10.1152/Ajpheart.00068.2016  0.624
2017 Baliga NS, Björkegren JL, Boeke JD, Boutros M, Crawford NP, Dudley AM, Farber CR, Jones A, Levey AI, Lusis AJ, Mak HC, Nadeau JH, Noyes MB, Petretto E, Seyfried NT, et al. The State of Systems Genetics in 2017. Cell Systems. 4: 7-15. PMID 28125793 DOI: 10.1016/J.Cels.2017.01.005  0.311
2017 Laakso M, Kuusisto J, Stancakova A, Kuulasmaa T, Pajukanta P, Lusis AJ, Collins FS, Mohlke K, Boehnke M. METabolic Syndrome In Men (METSIM) Study: a resource for studies of metabolic and cardiovascular diseases. Journal of Lipid Research. PMID 28119442 DOI: 10.1194/Jlr.O072629  0.359
2017 Rau CD, Civelek M, Pan C, Lusis AJ. A Suite of Tools for Biologists That Improve Accessibility and Visualization of Large Systems Genetics Datasets: Applications to the Hybrid Mouse Diversity Panel. Methods in Molecular Biology (Clifton, N.J.). 1488: 153-188. PMID 27933524 DOI: 10.1007/978-1-4939-6427-7_7  0.651
2016 von Scheidt M, Zhao Y, Kurt Z, Pan C, Zeng L, Yang X, Schunkert H, Lusis AJ. Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis. Cell Metabolism. PMID 27916529 DOI: 10.1016/J.Cmet.2016.11.001  0.412
2016 Rau CD, Romay MC, Tuteryan M, Wang JJ, Santolini M, Ren S, Karma A, Weiss JN, Wang Y, Lusis AJ. Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell Systems. PMID 27866946 DOI: 10.1016/J.Cels.2016.10.016  0.654
2016 Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Mäkinen VP, Yang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. Bmc Genomics. 17: 874. PMID 27814671 DOI: 10.1186/S12864-016-3198-9  0.666
2016 Norheim F, Hui ST, Kulahcioglu E, Mehrabian M, Cantor RM, Pan C, Parks BW, Lusis AJ. Genetic and hormonal control of hepatic steatosis in female and male mice. Journal of Lipid Research. PMID 27811231 DOI: 10.1194/Jlr.M071522  0.372
2016 Joo JW, Kang EY, Org E, Furlotte N, Parks B, Hormozdiari F, Lusis AJ, Eskin E. Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure. Genetics. PMID 27770036 DOI: 10.1534/Genetics.116.189712  0.333
2016 Kang EY, Martin L, Mangul S, Isvilanonda W, Zou J, Ben-David E, Han B, Lusis AJ, Shifman S, Eskin E. Discovering SNPs Regulating Human Gene Expression Using Allele Specific Expression from RNA-Seq Data. Genetics. PMID 27765809 DOI: 10.1534/Genetics.115.177246  0.401
2016 Wågsäter D, Vorkapic E, van Stijn CM, Kim J, Lusis AJ, Eriksson P, Tangirala RK. Elevated Adiponectin Levels Suppress Perivascular and Aortic Inflammation and Prevent AngII-induced Advanced Abdominal Aortic Aneurysms. Scientific Reports. 6: 31414. PMID 27659201 DOI: 10.1038/Srep31414  0.312
2016 Hasin-Brumshtein Y, Khan AH, Hormozdiari F, Pan C, Parks BW, Petyuk VA, Piehowski PD, Bruemmer A, Pellegrini M, Xiao X, Eskin E, Smith RD, Lusis AJ, Smith DJ. Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes. Elife. 5. PMID 27623010 DOI: 10.7554/Elife.15614  0.459
2016 Codoni V, Blum Y, Civelek M, Proust C, Franzén O, Björkegren JL, Le Goff W, Cambien F, Lusis AJ, Trégouët DA. Preservation Analysis of Macrophage Gene Co-expression Between Human and Mouse Identifies PARK2 as a Genetically controlled Master Regulator of Oxydative Phosphorylation in Humans. G3 (Bethesda, Md.). PMID 27558669 DOI: 10.1534/G3.116.033894  0.427
2016 Salehi P, Myint A, Kim YJ, Ge MX, Lavinsky J, Ho MK, Crow AL, Cruz C, Monges-Hernadez M, Wang J, Hartiala J, Zhang LI, Allayee H, Lusis AJ, Ohyama T, et al. Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice. Journal of the Association For Research in Otolaryngology : Jaro. PMID 27539716 DOI: 10.1007/S10162-016-0578-4  0.425
2016 Lavinsky J, Ge M, Crow AL, Pan C, Wang J, Dermanaki PS, Myint A, Eskin E, Allayee H, Lusis AJ, Friedman RA. The Genetic Architecture of Noise-induced Hearing Loss: Evidence for a Gene-by-Environment Interaction. G3 (Bethesda, Md.). PMID 27520957 DOI: 10.1534/G3.116.032516  0.405
2016 Du J, Leung A, Trac C, Lee M, Parks BW, Lusis AJ, Natarajan R, Schones DE. Chromatin variation associated with liver metabolism is mediated by transposable elements. Epigenetics & Chromatin. 9: 28. PMID 27398095 DOI: 10.1186/S13072-016-0078-0  0.316
2016 Wang JJ, Rau C, Avetisyan R, Ren S, Romay MC, Stolin G, Gong KW, Wang Y, Lusis AJ. Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. Plos Genetics. 12: e1006038. PMID 27385019 DOI: 10.1371/Journal.Pgen.1006038  0.665
2016 Org E, Mehrabian M, Parks BW, Shipkova P, Liu X, Drake TA, Lusis AJ. Sex differences and hormonal effects on gut microbiota composition in mice. Gut Microbes. 0. PMID 27355107 DOI: 10.1080/19490976.2016.1203502  0.351
2016 Hormozdiari F, Kang EY, Bilow M, Ben-David E, Vulpe C, McLachlan S, Lusis AJ, Han B, Eskin E. Imputing Phenotypes for Genome-wide Association Studies. American Journal of Human Genetics. PMID 27292110 DOI: 10.1016/J.Ajhg.2016.04.013  0.331
2016 Karbassi E, Monte E, Chapski DJ, Lopez R, Rosa Garrido M, Kim J, Wisniewski NN, Rau CC, Wang JJ, Weiss JN, Wang Y, Lusis AJ, Vondriska TM. Relationship of Disease-Associated Gene Expression to Cardiac Phenotype is Buffered by Genetic Diversity and Chromatin Regulation. Physiological Genomics. physiolgenomics.0003. PMID 27287924 DOI: 10.1152/Physiolgenomics.00035.2016  0.438
2016 Monte E, Rosa-Garrido M, Karbassi E, Chen H, Lopez R, Rau CD, Wang J, Nelson SF, Wu Y, Stefani E, Lusis AJ, Wang Y, Kurdistani SK, Franklin S, Vondriska TM. Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins HMGB and CTCF: Implications for Transcriptional Regulation. The Journal of Biological Chemistry. PMID 27226577 DOI: 10.1074/Jbc.M116.719633  0.632
2016 Talukdar HA, Foroughi Asl H, Jain RK, Ermel R, Ruusalepp A, Franzén O, Kidd BA, Readhead B, Giannarelli C, Kovacic JC, Ivert T, Dudley JT, Civelek M, Lusis AJ, Schadt EE, et al. Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease. Cell Systems. 2: 196-208. PMID 27135365 DOI: 10.1016/J.Cels.2016.02.002  0.406
2016 Lusis AJ, Seldin M, Allayee H, Bennett BJ, Civelek M, Davis RC, Eskin E, Farber C, Hui ST, Mehrabian M, Norheim F, Pan C, Parks B, Rau C, Smith DJ, et al. The Hybrid Mouse Diversity Panel: A Resource for Systems Genetics Analyses of Metabolic and Cardiovascular Traits. Journal of Lipid Research. PMID 27099397 DOI: 10.1194/Jlr.R066944  0.7
2016 Chattopadhyay A, Navab M, Hough G, Grijalva V, Mukherjee P, Fogelman HR, Hwang LH, Faull KF, Lusis AJ, Reddy ST, Fogelman AM. Tomatoes expressing the 6F Peptide Ameliorate the Increase in Oxidized Phospholipids in the Jejunum of Mice Fed Unsaturated Lysophosphatidylcholine or Western Diet. Journal of Lipid Research. PMID 26965826 DOI: 10.1194/Jlr.M064352  0.325
2016 Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Sevag Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, ... ... Lusis AJ, et al. Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. Plos Genetics. 12: e1005913. PMID 26934746 DOI: 10.1371/journal.pgen.1005913  0.7
2016 Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx BW, Jansen R, de Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E, Alvarez M, Civelek M, Lusis AJ, et al. Integrative approaches for large-scale transcriptome-wide association studies. Nature Genetics. PMID 26854917 DOI: 10.1038/Ng.3506  0.435
2016 Chen H, Orozco LD, Wang J, Rau CD, Rubbi L, Ren S, Wang Y, Pellegrini M, Lusis AJ, Vondriska TM. DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. Circulation Research. PMID 26838786 DOI: 10.1161/Circresaha.115.305298  0.778
2016 Hasin-Brumshtein Y, Khan AH, Hormozdiari F, Pan C, Parks BW, Petyuk VA, Piehowski PD, Brümmer A, Pellegrini M, Xiao X, Eskin E, Smith RD, Lusis AJ, Smith DJ. Author response: Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes Elife. DOI: 10.7554/Elife.15614.024  0.348
2015 Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, ... ... Lusis AJ, et al. Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. Plos Genetics. 11: e1005711. PMID 26694027 DOI: 10.1371/Journal.Pgen.1005711  0.775
2015 Wang Z, Roberts AB, Buffa JA, Levison BS, Zhu W, Org E, Gu X, Huang Y, Zamanian-Daryoush M, Culley MK, DiDonato AJ, Fu X, Hazen JE, Krajcik D, DiDonato JA, ... Lusis AJ, et al. Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis. Cell. 163: 1585-95. PMID 26687352 DOI: 10.1016/J.Cell.2015.11.055  0.301
2015 Pamir N, Hutchins P, Ronsein G, Vaisar T, Reardon CA, Getz GS, Lusis AJ, Heinecke JW. Proteomic analysis of HDL from inbred mice strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway. Journal of Lipid Research. PMID 26673204 DOI: 10.1194/Jlr.M063701  0.337
2015 Roman TS, Marvelle AF, Fogarty MP, Vadlamudi S, Gonzalez AJ, Buchkovich ML, Huyghe JR, Fuchsberger C, Jackson AU, Wu Y, Civelek M, Lusis AJ, Gaulton KJ, Sethupathy P, Kangas AJ, et al. Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol. American Journal of Human Genetics. 97: 801-15. PMID 26637976 DOI: 10.1016/J.Ajhg.2015.10.016  0.329
2015 Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, et al. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of Experimental Medicine. PMID 26552708 DOI: 10.1084/Jem.20150603  0.337
2015 Crow AL, Ohmen J, Wang J, Lavinsky J, Hartiala J, Li Q, Li X, Salehide P, Eskin E, Pan C, Lusis AJ, Allayee H, Friedman RA. The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency Specific Genetic Determinants. G3 (Bethesda, Md.). PMID 26342000 DOI: 10.1534/G3.115.021592  0.419
2015 Schrauwen I, Hasin-Brumshtein Y, Corneveaux JJ, Ohmen J, White C, Allen AN, Lusis AJ, Van Camp G, Huentelman MJ, Friedman RA. A comprehensive catalogue of the coding and non-coding transcripts of the human inner ear. Hearing Research. PMID 26341477 DOI: 10.1016/J.Heares.2015.08.013  0.311
2015 Brænne I, Civelek M, Vilne B, Di Narzo A, Johnson AD, Zhao Y, Reiz B, Codoni V, Webb TR, Foroughi Asl H, Hamby SE, Zeng L, Trégouët DA, Hao K, Topol EJ, ... ... Lusis AJ, et al. Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26293461 DOI: 10.1161/Atvbaha.115.306108  0.338
2015 Org E, Parks BW, Joo JW, Emert B, Schwartzman W, Kang EY, Mehrabian M, Pan C, Knight R, Gunsalus R, Drake TA, Eskin E, Lusis AJ. Genetic and environmental control of host-gut microbiota interactions. Genome Research. PMID 26260972 DOI: 10.1101/Gr.194118.115  0.393
2015 Rau CD, Parks B, Wang Y, Eskin E, Simecek P, Churchill GA, Lusis AJ. High Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda, Md.). PMID 26224782 DOI: 10.1534/G3.115.020784  0.662
2015 Org E, Mehrabian M, Lusis AJ. Unraveling the environmental and genetic interactions in atherosclerosis: Central role of the gut microbiota. Atherosclerosis. 241: 387-99. PMID 26071662 DOI: 10.1016/J.Atherosclerosis.2015.05.035  0.323
2015 Hui ST, Parks BW, Org E, Norheim F, Che N, Pan C, Castellani LW, Charugundla S, Dirks DL, Psychogios N, Neuhaus I, Gerszten RE, Kirchgessner T, Gargalovic PS, Lusis AJ. The genetic architecture of NAFLD among inbred strains of mice. Elife. 4. PMID 26067236 DOI: 10.7554/Elife.05607  0.401
2015 Zhou X, Crow AL, Hartiala J, Spindler TJ, Ghazalpour A, Barsky LW, Bennett BB, Parks BW, Eskin E, Jain R, Epstein JA, Lusis AJ, Adams GB, Allayee H. The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. Stem Cell Reports. PMID 26050929 DOI: 10.1016/J.Stemcr.2015.05.008  0.724
2015 Orozco LD, Morselli M, Rubbi L, Guo W, Go J, Shi H, Lopez D, Furlotte NA, Bennett BJ, Farber CR, Ghazalpour A, Zhang MQ, Bahous R, Rozen R, Lusis AJ, et al. Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice. Cell Metabolism. 21: 905-17. PMID 26039453 DOI: 10.1016/J.Cmet.2015.04.025  0.809
2015 Wu C, Huang RT, Kuo CH, Kumar S, Kim CW, Lin YC, Chen YJ, Birukova A, Birukov KG, Dulin N, Civelek M, Lusis AJ, Loyer X, Tedgui A, Dai G, et al. Mechano-Sensitive PPAP2B Regulates Endothelial Responses to Athero-Relevant Hemodynamic Forces. Circulation Research. PMID 26034042 DOI: 10.1161/Circresaha.117.306457  0.327
2015 Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss. Plos Genetics. 11: e1005094. PMID 25880434 DOI: 10.1371/Journal.Pgen.1005094  0.406
2015 Rau CD, Lusis AJ, Wang Y. Genetics of common forms of heart failure: challenges and potential solutions. Current Opinion in Cardiology. 30: 222-7. PMID 25768955 DOI: 10.1097/Hco.0000000000000160  0.629
2015 Roux PF, Boitard S, Blum Y, Parks B, Montagner A, Mouisel E, Djari A, Esquerré D, Désert C, Boutin M, Leroux S, Lecerf F, Le Bihan-Duval E, Klopp C, Servin B, ... ... Lusis AJ, et al. Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation. G3 (Bethesda, Md.). 5: 517-29. PMID 25653314 DOI: 10.1534/G3.115.016865  0.422
2015 Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, ... ... Lusis AJ, et al. Genetic architecture of insulin resistance in the mouse. Cell Metabolism. 21: 334-46. PMID 25651185 DOI: 10.1016/J.Cmet.2015.01.002  0.688
2015 Hiyari S, Atti E, Camargo PM, Eskin E, Lusis AJ, Tetradis S, Pirih FQ. Heritability of periodontal bone loss in mice. Journal of Periodontal Research. 50: 730-6. PMID 25581386 DOI: 10.1111/Jre.12258  0.303
2015 Gregory JC, Buffa JA, Org E, Wang Z, Levison BS, Zhu W, Wagner MA, Bennett BJ, Li L, DiDonato JA, Lusis AJ, Hazen SL. Transmission of atherosclerosis susceptibility with gut microbial transplantation. The Journal of Biological Chemistry. 290: 5647-60. PMID 25550161 DOI: 10.1074/Jbc.M114.618249  0.32
2015 Rau CD, Wang J, Avetisyan R, Romay MC, Martin L, Ren S, Wang Y, Lusis AJ. Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice. Circulation. Cardiovascular Genetics. 8: 40-9. PMID 25480693 DOI: 10.1161/Circgenetics.113.000732  0.656
2015 Shih DM, Yu JM, Vergnes L, Dali-Youcef N, Champion MD, Devarajan A, Zhang P, Castellani LW, Brindley DN, Jamey C, Auwerx J, Reddy ST, Ford DA, Reue K, Lusis AJ. PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1185-97. PMID 25477283 DOI: 10.1096/Fj.14-260570  0.574
2015 Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, ... Lusis AJ, et al. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of Biological Chemistry. 290: 5566-81. PMID 25468909 DOI: 10.1074/Jbc.M114.606459  0.312
2015 Shih DM, Wang Z, Lee R, Meng Y, Che N, Charugundla S, Qi H, Wu J, Pan C, Brown JM, Vallim T, Bennett BJ, Graham M, Hazen SL, Lusis AJ. Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis. Journal of Lipid Research. 56: 22-37. PMID 25378658 DOI: 10.1194/Jlr.M051680  0.349
2015 Hui ST, Parks BW, Org E, Norheim F, Che N, Pan C, Castellani LW, Charugundla S, Dirks DL, Psychogios N, Neuhaus I, Gerszten RE, Kirchgessner T, Gargalovic PS, Lusis AJ. Author response: The genetic architecture of NAFLD among inbred strains of mice Elife. DOI: 10.7554/Elife.05607.027  0.369
2014 Gordts PL, Foley EM, Lawrence R, Sinha R, Lameda-Diaz C, Deng L, Nock R, Glass CK, Erbilgin A, Lusis AJ, Witztum JL, Esko JD. Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling. Cell Metabolism. 20: 813-26. PMID 25440058 DOI: 10.1016/J.Cmet.2014.09.016  0.799
2014 Wu X, Davis RC, McMillen TS, Schaeffer V, Zhou Z, Qi H, Mazandarani PN, Alialy R, Hudkins KL, Lusis AJ, LeBoeuf RC. Genetic modulation of diabetic nephropathy among mouse strains with Ins2 Akita mutation. Physiological Reports. 2. PMID 25428948 DOI: 10.14814/Phy2.12208  0.348
2014 Civelek M, Lusis AJ. From hairballs to an understanding of transendothelial migration of monocytes in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1809-10. PMID 25142882 DOI: 10.1161/Atvbaha.114.304151  0.356
2014 Albright J, Quizon PM, Lusis AJ, Bennett BJ. Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery. Bmc Medical Genomics. 7: 51. PMID 25115202 DOI: 10.1186/1755-8794-7-51  0.359
2014 Mäkinen VP, Civelek M, Meng Q, Zhang B, Zhu J, Levian C, Huan T, Segrè AV, Ghosh S, Vivar J, Nikpay M, Stewart AF, Nelson CP, Willenborg C, Erdmann J, ... ... Lusis AJ, et al. Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. Plos Genetics. 10: e1004502. PMID 25033284 DOI: 10.1371/Journal.Pgen.1004502  0.404
2014 Leung A, Parks BW, Du J, Trac C, Setten R, Chen Y, Brown K, Lusis AJ, Natarajan R, Schones DE. Open chromatin profiling in mice livers reveals unique chromatin variations induced by high fat diet. The Journal of Biological Chemistry. 289: 23557-67. PMID 25006255 DOI: 10.1074/Jbc.M114.581439  0.407
2014 Calkin AC, Lee SD, Kim J, Van Stijn CM, Wu XH, Lusis AJ, Hong C, Tangirala RI, Tontonoz P. Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice. Circulation Research. 115: 442-9. PMID 24935961 DOI: 10.1161/Circresaha.115.304440  0.319
2014 Hasin-Brumshtein Y, Hormozdiari F, Martin L, van Nas A, Eskin E, Lusis AJ, Drake TA. Allele-specific expression and eQTL analysis in mouse adipose tissue. Bmc Genomics. 15: 471. PMID 24927774 DOI: 10.1186/1471-2164-15-471  0.774
2014 Orozco LD, Rubbi L, Martin LJ, Fang F, Hormozdiari F, Che N, Smith AD, Lusis AJ, Pellegrini M. Intergenerational genomic DNA methylation patterns in mouse hybrid strains. Genome Biology. 15: R68. PMID 24887417 DOI: 10.1186/Gb-2014-15-5-R68  0.723
2014 Ghazalpour A, Bennett BJ, Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang WP, Kirchgessner T, Lusis AJ. Genetic regulation of mouse liver metabolite levels. Molecular Systems Biology. 10: 730. PMID 24860088 DOI: 10.15252/Msb.20135004  0.829
2014 Emert B, Hasin-Brumshtein Y, Springstead JR, Vakili L, Berliner JA, Lusis AJ. HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms. Journal of Lipid Research. 55: 1678-1692. PMID 24859737 DOI: 10.1194/Jlr.M047738  0.377
2014 Hartiala J, Bennett BJ, Tang WH, Wang Z, Stewart AF, Roberts R, McPherson R, Lusis AJ, Hazen SL, Allayee H. Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1307-13. PMID 24675659 DOI: 10.1161/Atvbaha.114.303252  0.358
2014 Csaki LS, Dwyer JR, Li X, Nguyen MH, Dewald J, Brindley DN, Lusis AJ, Yoshinaga Y, de Jong P, Fong L, Young SG, Reue K. Lipin-1 and lipin-3 together determine adiposity in vivo. Molecular Metabolism. 3: 145-54. PMID 24634820 DOI: 10.1016/J.Molmet.2013.11.008  0.373
2014 Ohmen J, Kang EY, Li X, Joo JW, Hormozdiari F, Zheng QY, Davis RC, Lusis AJ, Eskin E, Friedman RA. Genome-wide association study for age-related hearing loss (AHL) in the mouse: a meta-analysis. Journal of the Association For Research in Otolaryngology : Jaro. 15: 335-52. PMID 24570207 DOI: 10.1007/S10162-014-0443-2  0.398
2014 Okamoto R, Gery S, Gombart AF, Wang X, Castellani LW, Akagi T, Chen S, Arditi M, Ho Q, Lusis AJ, Li Q, Koeffler HP. Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- Mice Plos One. 9. PMID 24489659 DOI: 10.1371/Journal.Pone.0085341  0.377
2014 Kang EY, Han B, Furlotte N, Joo JW, Shih D, Davis RC, Lusis AJ, Eskin E. Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice. Plos Genetics. 10: e1004022. PMID 24415945 DOI: 10.1371/Journal.Pgen.1004022  0.41
2014 Civelek M, Lusis AJ. Systems genetics approaches to understand complex traits. Nature Reviews. Genetics. 15: 34-48. PMID 24296534 DOI: 10.1038/Nrg3575  0.384
2014 Ho MKL, Hasin Y, Lusis AJ, Friedman RA. RNA-Seq Analysis of Allele-Specific Expression in the Mouse Cochlea Otolaryngology–Head and Neck Surgery. 151: P226-P226. DOI: 10.1177/0194599814541629A281  0.379
2013 Maubaret CG, Salpea KD, Romanoski CE, Folkersen L, Cooper JA, Stephanou C, Li KW, Palmen J, Hamsten A, Neil A, Stephens JW, Lusis AJ, Eriksson P, Talmud PJ, Humphries SE, et al. Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease. Plos One. 8: e83122. PMID 24349443 DOI: 10.1371/Journal.Pone.0083122  0.673
2013 Lu G, Ota A, Ren S, Franklin S, Rau CD, Ping P, Lane TF, Zhou ZH, Reue K, Lusis AJ, Vondriska T, Wang Y. PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Molecular Metabolism. 2: 405-16. PMID 24327956 DOI: 10.1016/J.Molmet.2013.07.005  0.634
2013 Welch C, Lusis AJ. Genetics of common forms of heart disease: a long and winding road. Circulation Research. 113: 1035-6. PMID 24115066 DOI: 10.1161/Circresaha.113.302425  0.44
2013 Navab M, Hough G, Buga GM, Su F, Wagner AC, Meriwether D, Chattopadhyay A, Gao F, Grijalva V, Danciger JS, Van Lenten BJ, Org E, Lusis AJ, Pan C, Anantharamaiah GM, et al. Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid. Journal of Lipid Research. 54: 3403-18. PMID 24085744 DOI: 10.1194/Jlr.M042051  0.333
2013 Lagarrigue S, Martin L, Hormozdiari F, Roux PF, Pan C, van Nas A, Demeure O, Cantor R, Ghazalpour A, Eskin E, Lusis AJ. Analysis of allele-specific expression in mouse liver by RNA-Seq: a comparison with Cis-eQTL identified using genetic linkage. Genetics. 195: 1157-66. PMID 24026101 DOI: 10.1534/Genetics.113.153882  0.808
2013 Erbilgin A, Siemers N, Kayne P, Yang WP, Berliner J, Lusis AJ. Gene expression analyses of mouse aortic endothelium in response to atherogenic stimuli. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2509-17. PMID 23990205 DOI: 10.1161/Atvbaha.113.301989  0.801
2013 Huang Y, Wu Z, Riwanto M, Gao S, Levison BS, Gu X, Fu X, Wagner MA, Besler C, Gerstenecker G, Zhang R, Li XM, DiDonato AJ, Gogonea V, Tang WH, ... ... Lusis AJ, et al. Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. The Journal of Clinical Investigation. 123: 3815-28. PMID 23908111 DOI: 10.1172/Jci67478  0.301
2013 Shih DM, Shaposhnik Z, Meng Y, Rosales M, Wang X, Wu J, Ratiner B, Zadini F, Zadini G, Lusis AJ. Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3805-17. PMID 23752203 DOI: 10.1096/Fj.12-223008  0.332
2013 van Nas A, Pan C, Ingram-Drake LA, Ghazalpour A, Drake TA, Sobel EM, Papp JC, Lusis AJ. The systems genetics resource: a web application to mine global data for complex disease traits. Frontiers in Genetics. 4: 84. PMID 23730305 DOI: 10.3389/Fgene.2013.00084  0.813
2013 Erbilgin A, Civelek M, Romanoski CE, Pan C, Hagopian R, Berliner JA, Lusis AJ. Identification of CAD candidate genes in GWAS loci and their expression in vascular cells. Journal of Lipid Research. 54: 1894-905. PMID 23667179 DOI: 10.1194/Jlr.M037085  0.829
2013 Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, ... Lusis AJ, et al. Response to Pomozi et al's research commentary. Circulation Research. 112: e152-3. PMID 23625949 DOI: 10.1161/Circresaha.113.301666  0.533
2013 Weissglas-Volkov D, Aguilar-Salinas CA, Nikkola E, Deere KA, Cruz-Bautista I, Arellano-Campos O, Muñoz-Hernandez LL, Gomez-Munguia L, Ordoñez-Sánchez ML, Reddy PM, Lusis AJ, Matikainen N, Taskinen MR, Riba L, Cantor RM, et al. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. Journal of Medical Genetics. 50: 298-308. PMID 23505323 DOI: 10.1136/Jmedgenet-2012-101461  0.314
2013 Rau CD, Wisniewski N, Orozco LD, Bennett B, Weiss J, Lusis AJ. Maximal information component analysis: a novel non-linear network analysis method. Frontiers in Genetics. 4: 28. PMID 23487572 DOI: 10.3389/Fgene.2013.00028  0.768
2013 Davis RC, van Nas A, Bennett B, Orozco L, Pan C, Rau CD, Eskin E, Lusis AJ. Genome-wide association mapping of blood cell traits in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 105-18. PMID 23417284 DOI: 10.1007/S00335-013-9448-0  0.82
2013 Lagarrigue S, Hormozdiari F, Martin LJ, Lecerf F, Hasin Y, Rau C, Hagopian R, Xiao Y, Yan J, Drake TA, Ghazalpour A, Eskin E, Lusis AJ. Limited RNA editing in exons of mouse liver and adipose. Genetics. 193: 1107-15. PMID 23410828 DOI: 10.1534/Genetics.112.149054  0.754
2013 Parks BW, Nam E, Org E, Kostem E, Norheim F, Hui ST, Pan C, Civelek M, Rau CD, Bennett BJ, Mehrabian M, Ursell LK, He A, Castellani LW, Zinker B, ... ... Lusis AJ, et al. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metabolism. 17: 141-52. PMID 23312289 DOI: 10.1016/J.Cmet.2012.12.007  0.645
2013 Bennett BJ, de Aguiar Vallim TQ, Wang Z, Shih DM, Meng Y, Gregory J, Allayee H, Lee R, Graham M, Crooke R, Edwards PA, Hazen SL, Lusis AJ. Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metabolism. 17: 49-60. PMID 23312283 DOI: 10.1016/J.Cmet.2012.12.011  0.411
2013 Halperin DS, Pan C, Lusis AJ, Tontonoz P. Vestigial-like 3 is an inhibitor of adipocyte differentiation. Journal of Lipid Research. 54: 473-81. PMID 23152581 DOI: 10.1194/Jlr.M032755  0.338
2012 Calabrese G, Bennett BJ, Orozco L, Kang HM, Eskin E, Dombret C, De Backer O, Lusis AJ, Farber CR. Systems genetic analysis of osteoblast-lineage cells. Plos Genetics. 8: e1003150. PMID 23300464 DOI: 10.1371/Journal.Pgen.1003150  0.733
2012 Orozco LD, Bennett BJ, Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, Neuhaus I, Yordanova R, Gargalovic P, Pellegrini M, Kirchgessner T, ... Lusis AJ, et al. Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages. Cell. 151: 658-70. PMID 23101632 DOI: 10.1016/J.Cell.2012.08.043  0.817
2012 Kim JB, Deluna A, Mungrue IN, Vu C, Pouldar D, Civelek M, Orozco L, Wu J, Wang X, Charugundla S, Castellani LW, Rusek M, Jakubowski H, Jakobowski H, Lusis AJ. Effect of 9p21.3 coronary artery disease locus neighboring genes on atherosclerosis in mice. Circulation. 126: 1896-906. PMID 22952318 DOI: 10.1161/Circulationaha.111.064881  0.737
2012 Lee S, Birukov KG, Romanoski CE, Springstead JR, Lusis AJ, Berliner JA. Role of phospholipid oxidation products in atherosclerosis. Circulation Research. 111: 778-99. PMID 22935534 DOI: 10.1161/Circresaha.111.256859  0.699
2012 Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, ... ... Lusis AJ, et al. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 680-92. PMID 22892838 DOI: 10.1007/S00335-012-9411-5  0.811
2012 Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. "Good enough solutions" and the genetics of complex diseases. Circulation Research. 111: 493-504. PMID 22859671 DOI: 10.1161/Circresaha.112.269084  0.671
2012 Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, ... Lusis AJ, et al. ABCC6 localizes to the mitochondria-associated membrane. Circulation Research. 111: 516-20. PMID 22811557 DOI: 10.1161/Circresaha.112.276667  0.539
2012 Bennett BJ, Orozco L, Kostem E, Erbilgin A, Dallinga M, Neuhaus I, Guan B, Wang X, Eskin E, Lusis AJ. High-resolution association mapping of atherosclerosis loci in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1790-8. PMID 22723443 DOI: 10.1161/Atvbaha.112.253864  0.82
2012 Smolock EM, Ilyushkina IA, Ghazalpour A, Gerloff J, Murashev AN, Lusis AJ, Korshunov VA. Genetic locus on mouse chromosome 7 controls elevated heart rate. Physiological Genomics. 44: 689-98. PMID 22589454 DOI: 10.1152/Physiolgenomics.00041.2012  0.722
2012 Ishikawa K, Navab M, Lusis AJ. Vasculitis, Atherosclerosis, and Altered HDL Composition in Heme-Oxygenase-1-Knockout Mice. International Journal of Hypertension. 2012: 948203. PMID 22518297 DOI: 10.1155/2012/948203  0.349
2012 Furlotte NA, Kang EY, Van Nas A, Farber CR, Lusis AJ, Eskin E. Increasing association mapping power and resolution in mouse genetic studies through the use of meta-analysis for structured populations. Genetics. 191: 959-67. PMID 22505625 DOI: 10.1534/Genetics.112.140277  0.785
2012 Lusis AJ. Genetics of atherosclerosis. Trends in Genetics : Tig. 28: 267-75. PMID 22480919 DOI: 10.1016/J.Tig.2012.03.001  0.392
2012 Hong C, Bradley MN, Rong X, Wang X, Wagner A, Grijalva V, Castellani LW, Salazar J, Realegeno S, Boyadjian R, Fogelman AM, Van Lenten BJ, Reddy ST, Lusis AJ, Tangirala RK, et al. LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice Journal of Lipid Research. 53: 1126-1133. PMID 22454476 DOI: 10.1194/Jlr.M022061  0.37
2012 Arnold AP, Lusis AJ. Understanding the sexome: measuring and reporting sex differences in gene systems. Endocrinology. 153: 2551-5. PMID 22434084 DOI: 10.1210/En.2011-2134  0.322
2012 Lee S, Springstead JR, Parks BW, Romanoski CE, Palvolgyi R, Ho T, Nguyen P, Lusis AJ, Berliner JA. Metalloproteinase processing of HBEGF is a proximal event in the response of human aortic endothelial cells to oxidized phospholipids. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1246-54. PMID 22402363 DOI: 10.1161/Atvbaha.111.241257  0.665
2012 Lusis AJ. Life after GWAS: functional genomics in vascular biology. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 169. PMID 22258899 DOI: 10.1161/Atvbaha.111.243543  0.356
2012 Johansen CT, Wang J, McIntyre AD, Martins RA, Ban MR, Lanktree MB, Huff MW, Péterfy M, Mehrabian M, Lusis AJ, Kathiresan S, Anand SS, Yusuf S, Lee AH, Glimcher LH, et al. Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia. Circulation. Cardiovascular Genetics. 5: 66-72. PMID 22135386 DOI: 10.1161/Circgenetics.111.960864  0.389
2012 Davis RC, van Nas A, Castellani LW, Zhao Y, Zhou Z, Wen P, Yu S, Qi H, Rosales M, Schadt EE, Broman KW, Péterfy M, Lusis AJ. Systems genetics of susceptibility to obesity-induced diabetes in mice. Physiological Genomics. 44: 1-13. PMID 22010005 DOI: 10.1152/Physiolgenomics.00003.2011  0.792
2012 Langfelder P, Castellani LW, Zhou Z, Paul E, Davis R, Schadt EE, Lusis AJ, Horvath S, Mehrabian M. A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. Biochimica Et Biophysica Acta. 1821: 435-47. PMID 21807117 DOI: 10.1016/J.Bbalip.2011.07.014  0.436
2012 Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Lusis AJ, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127  0.755
2012 Plaisier CL, Bennett BJ, He A, Guan B, Lusis AJ, Reue K, Vergnes L. Zbtb16 has a role in brown adipocyte bioenergetics Nutrition and Diabetes. 2. DOI: 10.1038/Nutd.2012.21  0.365
2011 Terra JK, France B, Cote CK, Jenkins A, Bozue JA, Welkos SL, Bhargava R, Ho CL, Mehrabian M, Pan C, Lusis AJ, Davis RC, LeVine SM, Bradley KA. Allelic variation on murine chromosome 11 modifies host inflammatory responses and resistance to Bacillus anthracis. Plos Pathogens. 7: e1002469. PMID 22241984 DOI: 10.1371/Journal.Ppat.1002469  0.393
2011 Mungrue IN, Zhao P, Yao Y, Meng H, Rau C, Havel JV, Gorgels TG, Bergen AA, MacLellan WR, Drake TA, Boström KI, Lusis AJ. Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion model. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2806-12. PMID 21979437 DOI: 10.1161/Atvbaha.111.237420  0.601
2011 Kim JB, Xia YR, Romanoski CE, Lee S, Meng Y, Shi YS, Bourquard N, Gong KW, Port Z, Grijalva V, Reddy ST, Berliner JA, Lusis AJ, Shih DM. Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2624-33. PMID 21836061 DOI: 10.1161/Atvbaha.111.232827  0.666
2011 Romanoski CE, Che N, Yin F, Mai N, Pouldar D, Civelek M, Pan C, Lee S, Vakili L, Yang WP, Kayne P, Mungrue IN, Araujo JA, Berliner JA, Lusis AJ. Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1. Circulation Research. 109: e27-41. PMID 21737788 DOI: 10.1161/Circresaha.111.241869  0.763
2011 Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG, ... ... Lusis AJ, et al. Comparative analysis of proteome and transcriptome variation in mouse. Plos Genetics. 7: e1001393. PMID 21695224 DOI: 10.1371/Journal.Pgen.1001393  0.806
2011 Civelek M, Lusis AJ. Conducting the metabolic syndrome orchestra. Nature Genetics. 43: 506-8. PMID 21614088 DOI: 10.1038/Ng.842  0.386
2011 Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, ... Lusis AJ, et al. Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. Plos Genetics. 7: e1002038. PMID 21490954 DOI: 10.1371/Journal.Pgen.1002038  0.811
2011 Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, Dugar B, Feldstein AE, Britt EB, Fu X, Chung YM, Wu Y, Schauer P, Smith JD, Allayee H, Tang WH, ... ... Lusis AJ, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature. 472: 57-63. PMID 21475195 DOI: 10.1038/Nature09922  0.371
2011 Park CC, Gale GD, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, Horvath S, Lusis AJ, Ophoff RA, Smith DJ. Gene networks associated with conditional fear in mice identified using a systems genetics approach. Bmc Systems Biology. 5: 43. PMID 21410935 DOI: 10.1186/1752-0509-5-43  0.73
2011 Suwanwela J, Farber CR, Haung BL, Song B, Pan C, Lyons KM, Lusis AJ. Systems genetics analysis of mouse chondrocyte differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 747-60. PMID 20954177 DOI: 10.1002/Jbmr.271  0.81
2011 Barajas B, Che N, Yin F, Rowshanrad A, Orozco LD, Gong KW, Wang X, Castellani LW, Reue K, Lusis AJ, Araujo JA. NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 58-66. PMID 20947826 DOI: 10.1161/Atvbaha.110.210906  0.751
2010 Yang X, Peterson L, Thieringer R, Deignan JL, Wang X, Zhu J, Wang S, Zhong H, Stepaniants S, Beaulaurier J, Wang IM, Rosa R, Cumiskey AM, Luo JM, Luo Q, ... ... Lusis AJ, et al. Identification and validation of genes affecting aortic lesions in mice. The Journal of Clinical Investigation. 120: 2414-22. PMID 20577049 DOI: 10.1172/Jci42742  0.631
2010 Hsu YH, Zillikens MC, Wilson SG, Farber CR, Demissie S, Soranzo N, Bianchi EN, Grundberg E, Liang L, Richards JB, Estrada K, Zhou Y, van Nas A, Moffatt MF, Zhai G, ... ... Lusis AJ, et al. An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. Plos Genetics. 6: e1000977. PMID 20548944 DOI: 10.1371/Journal.Pgen.1000977  0.793
2010 van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS, Schadt EE, Drake T, Lusis AJ. Expression quantitative trait loci: replication, tissue- and sex-specificity in mice. Genetics. 185: 1059-68. PMID 20439777 DOI: 10.1534/Genetics.110.116087  0.821
2010 Tarling EJ, Bojanic DD, Tangirala RK, Wang X, Lovgren-Sandblom A, Lusis AJ, Bjorkhem I, Edwards PA. Impaired development of atherosclerosis in Abcg1-/- Apoe-/- mice: identification of specific oxysterols that both accumulate in Abcg1-/- Apoe-/- tissues and induce apoptosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1174-80. PMID 20299684 DOI: 10.1161/Atvbaha.110.205617  0.337
2010 Shih DM, Xia YR, Yu JM, Lusis AJ. Temporal and tissue-specific patterns of Pon3 expression in mouse: in situ hybridization analysis. Advances in Experimental Medicine and Biology. 660: 73-87. PMID 20221872 DOI: 10.1007/978-1-60761-350-3_8  0.603
2010 Romanoski CE, Lee S, Kim MJ, Ingram-Drake L, Plaisier CL, Yordanova R, Tilford C, Guan B, He A, Gargalovic PS, Kirchgessner TG, Berliner JA, Lusis AJ. Systems genetics analysis of gene-by-environment interactions in human cells. American Journal of Human Genetics. 86: 399-410. PMID 20170901 DOI: 10.1016/J.Ajhg.2010.02.002  0.72
2010 Gargalovic PS, Erbilgin A, Kohannim O, Pagnon J, Wang X, Castellani L, LeBoeuf R, Peterson ML, Spear BT, Lusis AJ. Quantitative trait locus mapping and identification of Zhx2 as a novel regulator of plasma lipid metabolism Circulation: Cardiovascular Genetics. 3: 60-67. PMID 20160197 DOI: 10.1161/Circgenetics.109.902320  0.82
2010 Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, ... ... Lusis AJ, et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Research. 20: 281-90. PMID 20054062 DOI: 10.1101/Gr.099234.109  0.818
2010 Lusis AJ, Weiss JN. Cardiovascular networks: systems-based approaches to cardiovascular disease. Circulation. 121: 157-70. PMID 20048233 DOI: 10.1161/Circulationaha.108.847699  0.341
2010 Weinstein MM, Yin L, Tu Y, Wang X, Wu X, Castellani LW, Walzem RL, Lusis AJ, Fong LG, Beigneux AP, Young SG. Chylomicronemia elicits atherosclerosis in mice-brief report Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 20-23. PMID 19815815 DOI: 10.1161/Atvbaha.109.196329  0.326
2009 Wang SS, Martin LJ, Schadt EE, Meng H, Wang X, Zhao W, Ingram-Drake L, Nebohacova M, Mehrabian M, Drake TA, Lusis AJ. Disruption of the aortic elastic lamina and medial calcification share genetic determinants in mice. Circulation. Cardiovascular Genetics. 2: 573-82. PMID 20031637 DOI: 10.1161/Circgenetics.109.860270  0.567
2009 Wu S, Mar-Heyming R, Dugum EZ, Kolaitis NA, Qi H, Pajukanta P, Castellani LW, Lusis AJ, Drake TA. Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice Human Molecular Genetics. 19: 597-608. PMID 19995791 DOI: 10.1093/Hmg/Ddp526  0.655
2009 Farber CR, Lusis AJ. Future of osteoporosis genetics: enhancing genome-wide association studies. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1937-42. PMID 19888896 DOI: 10.1359/Jbmr.091101  0.347
2009 Arnold AP, van Nas A, Lusis AJ. Systems biology asks new questions about sex differences. Trends in Endocrinology and Metabolism: Tem. 20: 471-6. PMID 19783453 DOI: 10.1016/J.Tem.2009.06.007  0.77
2009 Orozco LD, Cokus SJ, Ghazalpour A, Ingram-Drake L, Wang S, van Nas A, Che N, Araujo JA, Pellegrini M, Lusis AJ. Copy number variation influences gene expression and metabolic traits in mice. Human Molecular Genetics. 18: 4118-29. PMID 19648292 DOI: 10.1093/Hmg/Ddp360  0.825
2009 Shih DM, Lusis AJ. The roles of PON1 and PON2 in cardiovascular disease and innate immunity. Current Opinion in Lipidology. 20: 288-92. PMID 19474728 DOI: 10.1097/Mol.0B013E32832Ca1Ee  0.326
2009 White CH, Ohmen JD, Sheth S, Zebboudj AF, McHugh RK, Hoffman LF, Lusis AJ, Davis RC, Friedman RA. Genome-wide screening for genetic loci associated with noise-induced hearing loss. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 207-13. PMID 19337678 DOI: 10.1007/S00335-009-9178-5  0.617
2009 Farber CR, Aten JE, Farber EA, de Vera V, Gularte R, Islas-Trejo A, Wen P, Horvath S, Lucero M, Lusis AJ, Medrano JF. Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling. Physiological Genomics. 37: 294-302. PMID 19336533 DOI: 10.1152/Physiolgenomics.90245.2008  0.465
2009 Yang X, Deignan JL, Qi H, Zhu J, Qian S, Zhong J, Torosyan G, Majid S, Falkard B, Kleinhanz RR, Karlsson J, Castellani LW, Mumick S, Wang K, Xie T, ... ... Lusis AJ, et al. Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks. Nature Genetics. 41: 415-23. PMID 19270708 DOI: 10.1038/Ng.325  0.808
2009 Bennett BJ, Wang SS, Wang X, Wu X, Lusis AJ. Genetic regulation of atherosclerotic plaque size and morphology in the innominate artery of hyperlipidemic mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 348-55. PMID 19122174 DOI: 10.1161/Atvbaha.108.176685  0.581
2009 Mungrue IN, Pagnon J, Kohannim O, Gargalovic PS, Lusis AJ. CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade. Journal of Immunology (Baltimore, Md. : 1950). 182: 466-76. PMID 19109178 DOI: 10.4049/Jimmunol.182.1.466  0.363
2009 Bhasin KK, van Nas A, Martin LJ, Davis RC, Devaskar SU, Lusis AJ. Maternal low-protein diet or hypercholesterolemia reduces circulating essential amino acids and leads to intrauterine growth restriction. Diabetes. 58: 559-66. PMID 19073773 DOI: 10.2337/Db07-1530  0.731
2009 Wu S, Lusis AJ, Drake TA. A systems-based framework for understanding complex metabolic and cardiovascular disorders. Journal of Lipid Research. 50: S358-63. PMID 19033210 DOI: 10.1194/Jlr.R800067-Jlr200  0.615
2009 Shaposhnik Z, Wang X, Trias J, Fraser H, Lusis AJ. The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002). Journal of Lipid Research. 50: 623-9. PMID 19029066 DOI: 10.1194/Jlr.M800361-Jlr200  0.338
2009 van Nas A, Guhathakurta D, Wang SS, Yehya N, Horvath S, Zhang B, Ingram-Drake L, Chaudhuri G, Schadt EE, Drake TA, Arnold AP, Lusis AJ. Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. Endocrinology. 150: 1235-49. PMID 18974276 DOI: 10.1210/En.2008-0563  0.814
2009 Farber CR, van Nas A, Ghazalpour A, Aten JE, Doss S, Sos B, Schadt EE, Ingram-Drake L, Davis RC, Horvath S, Smith DJ, Drake TA, Lusis AJ. An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 105-16. PMID 18767929 DOI: 10.1359/Jbmr.080908  0.834
2009 Gale GD, Yazdi RD, Khan AH, Lusis AJ, Davis RC, Smith DJ. A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci. Molecular Psychiatry. 14: 631-45. PMID 18379576 DOI: 10.1038/Mp.2008.4  0.383
2009 Cervino AC, Li G, Edwards S, Zhu J, Laurie C, Tokiwa G, Lum PY, Wang S, Castellani LW, Lusis AJ, Carlson S, Sachs AB, Schadt EE. Corrigendum to "Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels" [Genomics 86 (2005) 505-517] (DOI:10.1016/j.ygeno.2005.07.010) Genomics. 93: 399. DOI: 10.1016/J.Ygeno.2008.12.005  0.617
2008 Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, ... ... Lusis AJ, et al. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. Plos One. 3: e3583. PMID 18974833 DOI: 10.1371/Journal.Pone.0003583  0.582
2008 Lusis AJ, Attie AD, Reue K. Metabolic syndrome: from epidemiology to systems biology. Nature Reviews. Genetics. 9: 819-30. PMID 18852695 DOI: 10.1038/Nrg2468  0.366
2008 Allayee H, Baylin A, Hartiala J, Wijesuriya H, Mehrabian M, Lusis AJ, Campos H. Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction. The American Journal of Clinical Nutrition. 88: 934-40. PMID 18842779 DOI: 10.1093/Ajcn/88.4.934  0.318
2008 Ghazalpour A, Doss S, Kang H, Farber C, Wen PZ, Brozell A, Castellanos R, Eskin E, Smith DJ, Drake TA, Lusis AJ. High-resolution mapping of gene expression using association in an outbred mouse stock. Plos Genetics. 4: e1000149. PMID 18688273 DOI: 10.1371/Journal.Pgen.1000149  0.798
2008 Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, ... ... Lusis AJ, et al. Mapping the genetic architecture of gene expression in human liver. Plos Biology. 6: e107. PMID 18462017 DOI: 10.1371/Journal.Pbio.0060107  0.83
2008 Aten JE, Fuller TF, Lusis AJ, Horvath S. Using genetic markers to orient the edges in quantitative trait networks: the NEO software. Bmc Systems Biology. 2: 34. PMID 18412962 DOI: 10.1186/1752-0509-2-34  0.379
2008 Park CC, Ahn S, Bloom JS, Lin A, Wang RT, Wu T, Sekar A, Khan AH, Farr CJ, Lusis AJ, Leahy RM, Lange K, Smith DJ. Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids. Nature Genetics. 40: 421-9. PMID 18362883 DOI: 10.1038/Ng.113  0.428
2008 Farber CR, Lusis AJ. Integrating global gene expression analysis and genetics. Advances in Genetics. 60: 571-601. PMID 18358333 DOI: 10.1016/S0065-2660(07)00420-8  0.41
2008 Bhattacharyya T, Nicholls SJ, Topol EJ, Zhang R, Yang X, Schmitt D, Fu X, Shao M, Brennan DM, Ellis SG, Brennan ML, Allayee H, Lusis AJ, Hazen SL. Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. Jama. 299: 1265-76. PMID 18349088 DOI: 10.1001/Jama.299.11.1265  0.533
2008 Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, ... ... Lusis AJ, et al. Variations in DNA elucidate molecular networks that cause disease. Nature. 452: 429-35. PMID 18344982 DOI: 10.1038/Nature06757  0.823
2008 Lusis AJ, Pajukanta P. A treasure trove for lipoprotein biology Nature Genetics. 40: 129-130. PMID 18227868 DOI: 10.1038/Ng0208-129  0.337
2008 Araujo JA, Barajas B, Kleinman M, Wang X, Bennett BJ, Gong KW, Navab M, Harkema J, Sioutas C, Lusis AJ, Nel AE. Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress. Circulation Research. 102: 589-96. PMID 18202315 DOI: 10.1161/Circresaha.107.164970  0.579
2008 Castellani LW, Nguyen CN, Charugundla S, Weinstein MM, Doan CX, Blaner WS, Wongsiriroj N, Lusis AJ. Apolipoprotein AII is a regulator of very low density lipoprotein metabolism and insulin resistance. The Journal of Biological Chemistry. 283: 11633-44. PMID 18160395 DOI: 10.1074/Jbc.M708995200  0.358
2008 McLin JP, Thompson LM, Lusis AJ, Davis RC, Steward O. Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid. Neurobiology of Disease. 29: 391-9. PMID 17996456 DOI: 10.1016/J.Nbd.2007.10.002  0.368
2008 Dow KM, Nordstrom SM, Sos BC, Davis RC, Lusis AJ, Weiss EJ. A Novel Tissue Factor Resistance Locus on Mouse Chromosome 11 Confers Protection from Thrombosis through Reduced Activity of Factor XI Blood. 112: 393-393. DOI: 10.1182/Blood.V112.11.393.393  0.354
2007 Bennett BJ, Romanoski CE, Lusis AJ. Network-centered view of coronary artery disease. Expert Review of Cardiovascular Therapy. 5: 1095-103. PMID 18035925 DOI: 10.1586/14779072.5.6.1095  0.668
2007 Wang SS, Shi W, Wang X, Velky L, Greenlee S, Wang MT, Drake TA, Lusis AJ. Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2671-6. PMID 17916774 DOI: 10.1161/Atvbaha.107.148106  0.577
2007 Martin LJ, Chen H, Liao X, Allayee H, Shih DM, Lee GS, Hovland DN, Robbins WA, Carnes K, Hess RA, Lusis AJ, Collins MD. FK506, a calcineurin inhibitor, prevents cadmium-induced testicular toxicity in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 474-85. PMID 17785681 DOI: 10.1093/Toxsci/Kfm229  0.38
2007 Lusis AJ, Yu J, Wang SS. The problem of passenger genes in transgenic mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2100-3. PMID 17690316 DOI: 10.1161/Atvbaha.107.147918  0.718
2007 Lee JC, Weissglas-Volkov D, Kyttälä M, Sinsheimer JS, Jokiaho A, de Bruin TW, Lusis AJ, Brennan ML, van Greevenbroek MM, van der Kallen CJ, Hazen SL, Pajukanta P. USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2222-7. PMID 17673701 DOI: 10.1161/Atvbaha.107.151530  0.54
2007 Fuller TF, Ghazalpour A, Aten JE, Drake TA, Lusis AJ, Horvath S. Weighted gene coexpression network analysis strategies applied to mouse weight. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 463-72. PMID 17668265 DOI: 10.1007/S00335-007-9043-3  0.726
2007 Bradley MN, Hong C, Chen M, Joseph SB, Wilpitz DC, Wang X, Lusis AJ, Collins A, Hseuh WA, Collins JL, Tangirala RK, Tontonoz P. Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. The Journal of Clinical Investigation. 117: 2337-46. PMID 17657314 DOI: 10.1172/Jci31909  0.35
2007 Gong KW, Zhao W, Li N, Barajas B, Kleinman M, Sioutas C, Horvath S, Lusis AJ, Nel A, Araujo JA. Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome Biology. 8: R149. PMID 17655762 DOI: 10.1186/Gb-2007-8-7-R149  0.59
2007 Wang SS, Schadt EE, Wang H, Wang X, Ingram-Drake L, Shi W, Drake TA, Lusis AJ. Identification of pathways for atherosclerosis in mice: integration of quantitative trait locus analysis and global gene expression data. Circulation Research. 101: e11-30. PMID 17641228 DOI: 10.1161/Circresaha.107.152975  0.665
2007 Moen CJ, Tholens AP, Voshol PJ, de Haan W, Havekes LM, Gargalovic P, Lusis AJ, van Dyk KW, Frants RR, Hofker MH, Rensen PC. The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglycerides. Journal of Lipid Research. 48: 2182-92. PMID 17609525 DOI: 10.1194/Jlr.M700009-Jlr200  0.332
2007 Davis RC, Jin A, Rosales M, Yu S, Xia X, Ranola K, Schadt EE, Lusis AJ. A genome-wide set of congenic mouse strains derived from CAST/Ei on a C57BL/6 background. Genomics. 90: 306-13. PMID 17600671 DOI: 10.1016/J.Ygeno.2007.05.009  0.356
2007 Orozco LD, Kapturczak MH, Barajas B, Wang X, Weinstein MM, Wong J, Deshane J, Bolisetty S, Shaposhnik Z, Shih DM, Agarwal A, Lusis AJ, Araujo JA. Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis. Circulation Research. 100: 1703-11. PMID 17495224 DOI: 10.1161/Circresaha.107.151720  0.766
2007 Gharavi NM, Gargalovic PS, Chang I, Araujo JA, Clark MJ, Szeto WL, Watson AD, Lusis AJ, Berliner JA. High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1346-53. PMID 17379837 DOI: 10.1161/Atvbaha.107.141283  0.599
2007 Shih DM, Xia YR, Wang XP, Wang SS, Bourquard N, Fogelman AM, Lusis AJ, Reddy ST. Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice. Circulation Research. 100: 1200-7. PMID 17379834 DOI: 10.1161/01.Res.0000264499.48737.69  0.604
2007 Meng H, Vera I, Che N, Wang X, Wang SS, Ingram-Drake L, Schadt EE, Drake TA, Lusis AJ. Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics. Proceedings of the National Academy of Sciences of the United States of America. 104: 4530-5. PMID 17360558 DOI: 10.1073/Pnas.0607620104  0.651
2007 Itoh Y, Melamed E, Yang X, Kampf K, Wang S, Yehya N, Van Nas A, Replogle K, Band MR, Clayton DF, Schadt EE, Lusis AJ, Arnold AP. Dosage compensation is less effective in birds than in mammals. Journal of Biology. 6: 2. PMID 17352797 DOI: 10.1186/Jbiol53  0.803
2007 Feng X, Li H, Rumbin AA, Wang X, La Cava A, Brechtelsbauer K, Castellani LW, Witztum JL, Lusis AJ, Tsao BP. ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia. Journal of Lipid Research. 48: 794-805. PMID 17259598 DOI: 10.1194/Jlr.M600512-Jlr200  0.349
2007 Stoltz DA, Ozer EA, Ng CJ, Yu JM, Reddy ST, Lusis AJ, Bourquard N, Parsek MR, Zabner J, Shih DM. Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L852-60. PMID 17122353 DOI: 10.1152/Ajplung.00370.2006  0.515
2006 Brouwers MC, Cantor RM, Kono N, Yoon JL, van der Kallen CJ, Bilderbeek-Beckers MA, van Greevenbroek MM, Lusis AJ, de Bruin TW. Heritability and genetic loci of fatty liver in familial combined hyperlipidemia. Journal of Lipid Research. 47: 2799-807. PMID 16971732 DOI: 10.1194/Jlr.M600312-Jlr200  0.35
2006 Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, Brozell A, Schadt EE, Drake TA, Lusis AJ, Horvath S. Integrating genetic and network analysis to characterize genes related to mouse weight. Plos Genetics. 2: e130. PMID 16934000 DOI: 10.1371/Journal.Pgen.0020130  0.827
2006 Gargalovic PS, Gharavi NM, Clark MJ, Pagnon J, Yang WP, He A, Truong A, Baruch-Oren T, Berliner JA, Kirchgessner TG, Lusis AJ. The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2490-6. PMID 16931790 DOI: 10.1161/01.Atv.0000242903.41158.A1  0.317
2006 Lusis AJ. A thematic review series: Systems biology approaches to metabolic and cardiovascular disorders Journal of Lipid Research. 47: 1887-1890. PMID 16924129 DOI: 10.1194/Jlr.E600004-Jlr200  0.351
2006 Gargalovic PS, Imura M, Zhang B, Gharavi NM, Clark MJ, Pagnon J, Yang WP, He A, Truong A, Patel S, Nelson SF, Horvath S, Berliner JA, Kirchgessner TG, Lusis AJ. Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids. Proceedings of the National Academy of Sciences of the United States of America. 103: 12741-6. PMID 16912112 DOI: 10.1073/Pnas.0605457103  0.41
2006 Ng CJ, Bourquard N, Grijalva V, Hama S, Shih DM, Navab M, Fogelman AM, Lusis AJ, Young S, Reddy ST. Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2. The Journal of Biological Chemistry. 281: 29491-500. PMID 16891303 DOI: 10.1074/Jbc.M605379200  0.361
2006 Estrada-Smith D, Collins AR, Wang X, Crockett C, Castellani L, Lusis AJ, Davis RC. Impact of chromosome 2 obesity loci on cardiovascular complications of insulin resistance in LDL receptor-deficient C57BL/6 mice. Diabetes. 55: 2265-71. PMID 16873689 DOI: 10.2337/Db06-0377  0.794
2006 Yang X, Schadt EE, Wang S, Wang H, Arnold AP, Ingram-Drake L, Drake TA, Lusis AJ. Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Research. 16: 995-1004. PMID 16825664 DOI: 10.1101/Gr.5217506  0.611
2006 Zhang Y, Wang X, Vales C, Lee FY, Lee H, Lusis AJ, Edwards PA. FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2316-21. PMID 16825595 DOI: 10.1161/01.Atv.0000235697.35431.05  0.355
2006 Drake TA, Schadt EE, Lusis AJ. Integrating genetic and gene expression data: Application to cardiovascular and metabolic traits in mice Mammalian Genome. 17: 466-479. PMID 16783628 DOI: 10.1007/S00335-005-0175-Z  0.485
2006 Brouwers MC, Kono N, van Greevenbroek MM, van der Kallen CJ, Lusis AJ, de Bruin TW, Cantor RM. Longitudinal differences in familial combined hyperlipidemia quantitative trait loci. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: e118-9. PMID 16709947 DOI: 10.1161/01.Atv.0000221232.79877.C7  0.391
2006 Bhasin KK, Yu JM, Tward A, Shih D, Campbell DA, Lusis AJ. Trypanosoma congolense: paraoxonase 1 prolongs survival of infected mice. Experimental Parasitology. 114: 240-5. PMID 16682028 DOI: 10.1016/J.Exppara.2006.03.010  0.542
2006 Castellani LW, Chang JJ, Wang X, Lusis AJ, Reynolds WF. Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males. Journal of Lipid Research. 47: 1366-77. PMID 16639078 DOI: 10.1194/Jlr.M600005-Jlr200  0.364
2006 Lum PY, Chen Y, Zhu J, Lamb J, Melmed S, Wang S, Drake TA, Lusis AJ, Schadt EE. Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes. Journal of Neurochemistry. 97: 50-62. PMID 16635250 DOI: 10.1111/J.1471-4159.2006.03661.X  0.631
2006 Ghazalpour A, Wang X, Lusis AJ, Mehrabian M. Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice. Genetics. 173: 943-51. PMID 16624897 DOI: 10.1534/Genetics.106.057455  0.717
2006 Sheth SS, Bodnar JS, Ghazalpour A, Thipphavong CK, Tsutsumi S, Tward AD, Demant P, Kodama T, Aburatani H, Lusis AJ. Hepatocellular carcinoma in Txnip-deficient mice. Oncogene. 25: 3528-36. PMID 16607285 DOI: 10.1038/Sj.Onc.1209394  0.786
2006 Su Z, Li Y, James JC, Matsumoto AH, Helm GA, Lusis AJ, Shi W. Genetic linkage of hyperglycemia, body weight and serum amyloid-P in an intercross between C57BL/6 and C3H apolipoprotein E-deficient mice. Human Molecular Genetics. 15: 1650-8. PMID 16595606 DOI: 10.1093/Hmg/Ddl088  0.394
2006 Lee JC, Lusis AJ, Pajukanta P. Familial combined hyperlipidemia: Upstream transcription factor 1 and beyond Current Opinion in Lipidology. 17: 101-109. PMID 16531745 DOI: 10.1097/01.Mol.0000217890.54875.13  0.333
2006 Miyoshi T, Li Y, Shih DM, Wang X, Laubach VE, Matsumoto AH, Helm GA, Lusis AJ, Shi W. Deficiency of inducible NO synthase reduces advanced but not early atherosclerosis in apolipoprotein E-deficient mice. Life Sciences. 79: 525-31. PMID 16516241 DOI: 10.1016/J.Lfs.2006.01.043  0.343
2006 Wang S, Yehya N, Schadt EE, Wang H, Drake TA, Lusis AJ. Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity Plos Genetics. 2. PMID 16462940 DOI: 10.1371/Journal.Pgen.0020015  0.642
2006 Su Z, Li Y, James JC, McDuffie M, Matsumoto AH, Helm GA, Weber JL, Lusis AJ, Shi W. Quantitative trait locus analysis of atherosclerosis in an intercross between C57BL/6 and C3H mice carrying the mutant apolipoprotein E gene. Genetics. 172: 1799-807. PMID 16387874 DOI: 10.1534/Genetics.105.051912  0.424
2006 Shih DM, Kast-Woelbern HR, Wong J, Xia YR, Edwards PA, Lusis AJ. A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids. Journal of Lipid Research. 47: 384-92. PMID 16269825 DOI: 10.1194/Jlr.M500378-Jlr200  0.359
2005 Drake TA, Schadt EE, Davis RC, Lusis AJ. Integrating genetic and gene expression data to study the metabolic syndrome and diabetes in mice. American Journal of Therapeutics. 12: 503-11. PMID 16280644 DOI: 10.1097/01.Mjt.0000178775.39149.64  0.415
2005 Ozer EA, Pezzulo A, Shih DM, Chun C, Furlong C, Lusis AJ, Greenberg EP, Zabner J. Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing. Fems Microbiology Letters. 253: 29-37. PMID 16260097 DOI: 10.1016/J.Femsle.2005.09.023  0.301
2005 Mehrabian M, Allayee H, Stockton J, Lum PY, Drake TA, Castellani LW, Suh M, Armour C, Edwards S, Lamb J, Lusis AJ, Schadt EE. Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits. Nature Genetics. 37: 1224-33. PMID 16200066 DOI: 10.1038/Ng1619  0.472
2005 Cervino AC, Li G, Edwards S, Zhu J, Laurie C, Tokiwa G, Lum PY, Wang S, Castellani LW, Castellini LW, Lusis AJ, Carlson S, Sachs AB, Schadt EE. Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels. Genomics. 86: 505-17. PMID 16126366 DOI: 10.1016/J.Ygeno.2005.07.010  0.649
2005 Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG. Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. Neurotoxicology. 26: 651-9. PMID 16112327 DOI: 10.1016/J.Neuro.2004.08.002  0.366
2005 Davis RC, Schadt EE, Smith DJ, Hsieh EW, Cervino AC, van Nas A, Rosales M, Doss S, Meng H, Allayee H, Lusis AJ. A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background. Genomics. 86: 259-70. PMID 16039824 DOI: 10.1016/j.ygeno.2005.05.010  0.8
2005 Ghazalpour A, Doss S, Sheth SS, Ingram-Drake LA, Schadt EE, Lusis AJ, Drake TA. Genomic analysis of metabolic pathway gene expression in mice. Genome Biology. 6: R59. PMID 15998448 DOI: 10.1186/Gb-2005-6-7-R59  0.825
2005 Huertas-Vazquez A, Aguilar-Salinas C, Lusis AJ, Cantor RM, Canizales-Quinteros S, Lee JC, Mariana-Nuñez L, Riba-Ramirez RM, Jokiaho A, Tusie-Luna T, Pajukanta P. Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1985-91. PMID 15976322 DOI: 10.1161/01.Atv.0000175297.37214.A0  0.321
2005 Schadt EE, Lamb J, Yang X, Zhu J, Edwards S, Guhathakurta D, Sieberts SK, Monks S, Reitman M, Zhang C, Lum PY, Leonardson A, Thieringer R, Metzger JM, Yang L, ... ... Lusis AJ, et al. An integrative genomics approach to infer causal associations between gene expression and disease. Nature Genetics. 37: 710-7. PMID 15965475 DOI: 10.1038/Ng1589  0.419
2005 Doss S, Schadt EE, Drake TA, Lusis AJ. Cis-acting expression quantitative trait loci in mice. Genome Research. 15: 681-91. PMID 15837804 DOI: 10.1101/Gr.3216905  0.655
2005 Davis RC, Schadt EE, Cervino AC, Péterfy M, Lusis AJ. Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility. Diabetes. 54: 1191-9. PMID 15793261 DOI: 10.2337/Diabetes.54.4.1191  0.38
2005 Sheth SS, Castellani LW, Chari S, Wagg C, Thipphavong CK, Bodnar JS, Tontonoz P, Attie AD, Lopaschuk GD, Lusis AJ. Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition. Journal of Lipid Research. 46: 123-34. PMID 15520447 DOI: 10.1194/Jlr.M400341-Jlr200  0.803
2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, ... ... Lusis A, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics. 36: 1133-7. PMID 15514660 DOI: 10.1038/Ng1104-1133  0.373
2004 Lusis AJ, Mar R, Pajukanta P. Genetics of atherosclerosis. Annual Review of Genomics and Human Genetics. 5: 189-218. PMID 15485348 DOI: 10.1146/Annurev.Genom.5.061903.175930  0.709
2004 Castellani LW, Gargalovic P, Febbraio M, Charugundla S, Jien ML, Lusis AJ. Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II. Journal of Lipid Research. 45: 2377-87. PMID 15466364 DOI: 10.1194/Jlr.M400345-Jlr200  0.33
2004 Lusis AJ, Fogelman AM, Fonarow GC. Genetic basis of atherosclerosis: Part I. New genes and pathways Circulation. 110: 1868-1873. PMID 15451808 DOI: 10.1161/01.Cir.0000143041.58692.Cc  0.379
2004 Wang X, Gargalovic P, Wong J, Gu JL, Wu X, Qi H, Wen P, Xi L, Tan B, Gogliotti R, Castellani LW, Chatterjee A, Lusis AJ. Hyplip2, a new gene for combined hyperlipidemia and increased atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1928-34. PMID 15331434 DOI: 10.1161/01.Atv.0000143385.30354.Bb  0.44
2004 Cantor RM, de Bruin T, Kono N, Napier S, van Nas A, Allayee H, Lusis AJ. Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1935-41. PMID 15308552 DOI: 10.1161/01.Atv.0000142358.46276.A7  0.783
2004 Ghazalpour A, Doss S, Yang X, Aten J, Toomey EM, Van Nas A, Wang S, Drake TA, Lusis AJ. Thematic review series: The pathogenesis of atherosclerosis. Toward a biological network for atherosclerosis. Journal of Lipid Research. 45: 1793-805. PMID 15292376 DOI: 10.1194/Jlr.R400006-Jlr200  0.785
2004 Donnelly KL, Margosian MR, Sheth SS, Lusis AJ, Parks EJ. Increased lipogenesis and fatty acid reesterification contribute to hepatic triacylglycerol stores in hyperlipidemic Txnip-/- mice. The Journal of Nutrition. 134: 1475-80. PMID 15173414 DOI: 10.1093/Jn/134.6.1475  0.608
2004 Brown MD, Jin L, Jien ML, Matsumoto AH, Helm GA, Lusis AJ, Frank JS, Shi W. Lipid retention in the arterial wall of two mouse strains with different atherosclerosis susceptibility. Journal of Lipid Research. 45: 1155-61. PMID 15105414 DOI: 10.1194/Jlr.M400092-Jlr200  0.353
2004 Hui TY, Sheth SS, Diffley JM, Potter DW, Lusis AJ, Attie AD, Davis RA. Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. The Journal of Biological Chemistry. 279: 24387-93. PMID 15047687 DOI: 10.1074/Jbc.M401280200  0.615
2004 Shi W, Wang X, Wong J, Hedrick CC, Wong H, Castellani LW, Lusis AJ. Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice. Biochemical and Biophysical Research Communications. 317: 223-9. PMID 15047172 DOI: 10.1016/J.Bbrc.2004.03.037  0.623
2004 Liu D, Singh RP, Khan AH, Lusis AJ, Davis RC, Smith DJ. Mapping behavioral traits by use of genome-tagged mice. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 12: 158-65. PMID 15010345 DOI: 10.1097/00019442-200403000-00007  0.415
2004 Mar R, Pajukanta P, Allayee H, Groenendijk M, Dallinga-Thie G, Krauss RM, Sinsheimer JS, Cantor RM, de Bruin TW, Lusis AJ. Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia. Circulation Research. 94: 993-9. PMID 15001527 DOI: 10.1161/01.Res.0000124922.61830.F0  0.684
2004 Pajukanta P, Lilja HE, Sinsheimer JS, Cantor RM, Lusis AJ, Gentile M, Duan XJ, Soro-Paavonen A, Naukkarinen J, Saarela J, Laakso M, Ehnholm C, Taskinen MR, Peltonen L. Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1). Nature Genetics. 36: 371-6. PMID 14991056 DOI: 10.1038/Ng1320  0.405
2004 Estrada-Smith D, Castellani LW, Wong H, Wen PZ, Chui A, Lusis AJ, Davis RC. Dissection of multigenic obesity traits in congenic mouse strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 14-22. PMID 14727138 DOI: 10.1007/S00335-003-2294-8  0.807
2004 Welch CL, Bretschger S, Wen PZ, Mehrabian M, Latib N, Fruchart-Najib J, Fruchart JC, Myrick C, Lusis AJ. Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain. Physiological Genomics. 17: 48-59. PMID 14722362 DOI: 10.1152/Physiolgenomics.00124.2003  0.391
2004 Dwyer JH, Allayee H, Dwyer KM, Fan J, Wu H, Mar R, Lusis AJ, Mehrabian M. Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. The New England Journal of Medicine. 350: 29-37. PMID 14702425 DOI: 10.1016/J.Jvs.2004.03.014  0.695
2003 Liu D, Singh RP, Khan AH, Bhavsar K, Lusis AJ, Davis RC, Smith DJ. Identifying loci for behavioral traits using genome-tagged mice. Journal of Neuroscience Research. 74: 562-9. PMID 14598300 DOI: 10.1002/Jnr.10765  0.393
2003 Lusis AJ. Genetic factors in cardiovascular disease: 10 Questions Trends in Cardiovascular Medicine. 13: 309-316. PMID 14596945 DOI: 10.1016/J.Tcm.2003.08.001  0.357
2003 Nishimura I, Drake TA, Lusis AJ, Lyons KM, Nadeau JH, Zernik J. ENU large-scale mutagenesis and quantitative trait linkage (QTL) analysis in mice: novel technologies for searching polygenetic determinants of craniofacial abnormalities. Critical Reviews in Oral Biology and Medicine : An Official Publication of the American Association of Oral Biologists. 14: 320-30. PMID 14530301 DOI: 10.1177/154411130301400503  0.428
2003 Colinayo VV, Qiao JH, Wang X, Krass KL, Schadt E, Lusis AJ, Drake TA. Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 464-71. PMID 12925895 DOI: 10.1007/S00335-002-2187-2  0.805
2003 Shi W, Brown MD, Wang X, Wong J, Kallmes DF, Matsumoto AH, Helm GA, Drake TA, Lusis AJ. Genetic backgrounds but not sizes of atherosclerotic lesions determine medial destruction in the aortic root of apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1901-6. PMID 12920047 DOI: 10.1161/01.Atv.0000091249.34404.B7  0.321
2003 Allayee H, Ghazalpour A, Lusis AJ. Using mice to dissect genetic factors in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1501-9. PMID 12920046 DOI: 10.1161/01.Atv.0000090886.40027.Dc  0.743
2003 Araujo JA, Meng L, Tward AD, Hancock WW, Zhai Y, Lee A, Ishikawa K, Iyer S, Buelow R, Busuttil RW, Shih DM, Lusis AJ, Kupiec-Weglinski JW. Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse. Journal of Immunology (Baltimore, Md. : 1950). 171: 1572-80. PMID 12874251 DOI: 10.4049/Jimmunol.171.3.1572  0.593
2003 Krass KL, Colinayo V, Ghazalpour A, Vinters HV, Lusis AJ, Drake TA. Genetic loci contributing to age-related hippocampal lesions in mice. Neurobiology of Disease. 13: 102-8. PMID 12828934 DOI: 10.1016/S0969-9961(03)00034-2  0.799
2003 Cole TB, Jampsa RL, Walter BJ, Arndt TL, Richter RJ, Shih DM, Tward A, Lusis AJ, Jack RM, Costa LG, Furlong CE. Expression of human paraoxonase (PON1) during development. Pharmacogenetics. 13: 357-64. PMID 12777966 DOI: 10.1097/00008571-200306000-00007  0.318
2003 Allayee H, Castellani LW, Cantor RM, de Bruin TW, Lusis AJ. Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia. Circulation Research. 92: 1262-7. PMID 12738753 DOI: 10.1161/01.Res.0000075600.87675.16  0.347
2003 Schadt EE, Monks SA, Drake TA, Lusis AJ, Che N, Colinayo V, Ruff TG, Milligan SB, Lamb JR, Cavet G, Linsley PS, Mao M, Stoughton RB, Friend SH. Genetics of gene expression surveyed in maize, mouse and man Nature. 422: 297-302. PMID 12646919 DOI: 10.1038/Nature01434  0.825
2003 Pajukanta P, Allayee H, Krass KL, Kuraishy A, Soro A, Lilja HE, Mar R, Taskinen MR, Nuotio I, Laakso M, Rotter JI, de Bruin TW, Cantor RM, Lusis AJ, Peltonen L. Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q. American Journal of Human Genetics. 72: 903-17. PMID 12638083 DOI: 10.1086/374177  0.807
2002 Smith JB, Wadleigh DJ, Xia YR, Mar RA, Herschman HR, Lusis AJ. Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5. Immunogenetics. 54: 599-603. PMID 12439624 DOI: 10.1007/S00251-002-0501-5  0.728
2002 Attie AD, Krauss RM, Gray-Keller MP, Brownlie A, Miyazaki M, Kastelein JJ, Lusis AJ, Stalenhoef AF, Stoehr JP, Hayden MR, Ntambi JM. Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia. Journal of Lipid Research. 43: 1899-907. PMID 12401889 DOI: 10.1194/Jlr.M200189-Jlr200  0.328
2002 Smith DJ, Lusis AJ. The allelic structure of common disease. Human Molecular Genetics. 11: 2455-61. PMID 12351581 DOI: 10.1093/Hmg/11.20.2455  0.337
2002 Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 99: 11896-901. PMID 12193651 DOI: 10.1073/Pnas.182199799  0.336
2002 Mehrabian M, Allayee H, Wong J, Shi W, Wang XP, Shaposhnik Z, Funk CD, Lusis AJ, Shih W. Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice. Circulation Research. 91: 120-6. PMID 12142344 DOI: 10.1161/01.Res.0000028008.99774.7F  0.42
2002 Tward A, Xia YR, Wang XP, Shi YS, Park C, Castellani LW, Lusis AJ, Shih DM. Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice. Circulation. 106: 484-90. PMID 12135950 DOI: 10.1161/01.Cir.0000023623.87083.4F  0.347
2002 Colinayo VV, Qiao JH, Demant P, Krass K, Lusis AJ, Drake TA. Genetic characterization of the Dyscalc locus. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 283-8. PMID 12115029 DOI: 10.1007/S00335-001-2148-1  0.799
2002 Eiserich JP, Baldus S, Brennan ML, Ma W, Zhang C, Tousson A, Castro L, Lusis AJ, Nauseef WM, White CR, Freeman BA. Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science (New York, N.Y.). 296: 2391-4. PMID 12089442 DOI: 10.1126/Science.1106830  0.538
2002 Joseph SB, McKilligin E, Pei L, Watson MA, Collins AR, Laffitte BA, Chen M, Noh G, Goodman J, Hagger GN, Tran J, Tippin TK, Wang X, Lusis AJ, Hsueh WA, et al. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 7604-9. PMID 12032330 DOI: 10.1073/Pnas.112059299  0.372
2002 Allayee H, Krass KL, Pajukanta P, Cantor RM, van der Kallen CJ, Mar R, Rotter JI, de Bruin TW, Peltonen L, Lusis AJ. Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia. Circulation Research. 90: 926-31. PMID 11988495 DOI: 10.1161/01.Res.0000015885.27134.F0  0.813
2002 Shi W, Wang X, Tangchitpiyanond K, Wong J, Shi Y, Lusis AJ. Atherosclerosis in C3H/HeJ mice reconstituted with apolipoprotein E-null bone marrow Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 650-655. PMID 11950705 DOI: 10.1161/01.Atv.0000013388.03553.31  0.319
2002 Gukovskaya AS, Vaquero E, Zaninovic V, Gorelick FS, Lusis AJ, Brennan ML, Holland S, Pandol SJ. Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. Gastroenterology. 122: 974-84. PMID 11910350 DOI: 10.1053/Gast.2002.32409  0.49
2002 Sheth SS, Deluna A, Allayee H, Lusis AJ. Understanding atherosclerosis through mouse genetics. Current Opinion in Lipidology. 13: 181-9. PMID 11891421 DOI: 10.1097/00041433-200204000-00010  0.645
2002 Brennan ML, Wu W, Fu X, Shen Z, Song W, Frost H, Vadseth C, Narine L, Lenkiewicz E, Borchers MT, Lusis AJ, Lee JJ, Lee NA, Abu-Soud HM, Ischiropoulos H, et al. A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species. The Journal of Biological Chemistry. 277: 17415-27. PMID 11877405 DOI: 10.1074/Jbc.M112400200  0.473
2002 Miyake JH, Duong-Polk XT, Taylor JM, Du EZ, Castellani LW, Lusis AJ, Davis RA. Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 121-6. PMID 11788471 DOI: 10.1161/Hq0102.102588  0.344
2002 Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, ... Lusis AJ, et al. Positional cloning of the combined hyperlipidemia gene Hyplip1. Nature Genetics. 30: 110-6. PMID 11753387 DOI: 10.1038/Ng811  0.813
2001 Baldus S, Eiserich JP, Mani A, Castro L, Figueroa M, Chumley P, Ma W, Tousson A, White CR, Bullard DC, Brennan ML, Lusis AJ, Moore KP, Freeman BA. Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. The Journal of Clinical Investigation. 108: 1759-70. PMID 11748259 DOI: 10.1172/Jci12617  0.538
2001 Castellani LW, Lusis AJ. ApoA-II versus ApoA-I: two for one is not always a good deal. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1870-2. PMID 11742857 DOI: 10.1161/Atvb.21.12.1870  0.329
2001 Allayee H, de Bruin TW, Michelle Dominguez K, Cheng LS, Ipp E, Cantor RM, Krass KL, Keulen ET, Aouizerat BE, Lusis AJ, Rotter JI. Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p. Hypertension. 38: 773-8. PMID 11641285 DOI: 10.1161/Hy1001.092617  0.813
2001 Gaut JP, Yeh GC, Tran HD, Byun J, Henderson JP, Richter GM, Brennan ML, Lusis AJ, Belaaouaj A, Hotchkiss RS, Heinecke JW. Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis. Proceedings of the National Academy of Sciences of the United States of America. 98: 11961-6. PMID 11593004 DOI: 10.1073/Pnas.211190298  0.507
2001 Ivandic BT, Utz HF, Kaczmarek PM, Aherrahrou Z, Axtner SB, Klepsch C, Lusis AJ, Katus HA. New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice. Physiological Genomics. 6: 137-44. PMID 11526197 DOI: 10.1152/Physiolgenomics.2001.6.3.137  0.438
2001 Drake TA, Hannani K, Kabo JM, Villa V, Krass K, Lusis AJ. Genetic loci influencing natural variations in femoral bone morphometry in mice. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 19: 511-7. PMID 11518254 DOI: 10.1016/S0736-0266(00)00056-5  0.816
2001 Karlsson M, Reue K, Xia YR, Lusis AJ, Langin D, Tornqvist H, Holm C. Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene Gene. 272: 11-18. PMID 11470505 DOI: 10.1016/S0378-1119(01)00559-5  0.369
2001 Mehrabian M, Wong J, Wang X, Jiang Z, Shi W, Fogelman AM, Lusis AJ. Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia. Circulation Research. 89: 125-30. PMID 11463718 DOI: 10.1161/Hh1401.093458  0.645
2001 Iakoubova OA, Olsson CL, Dains KM, Ross DA, Andalibi A, Lau K, Choi J, Kalcheva I, Cunanan M, Louie J, Nimon V, Machrus M, Bentley LG, Beauheim C, Silvey S, ... ... Lusis AJ, et al. Genome-tagged mice (GTM): two sets of genome-wide congenic strains. Genomics. 74: 89-104. PMID 11374905 DOI: 10.1006/Geno.2000.6497  0.398
2001 Drake TA, Schadt E, Hannani K, Kabo JM, Krass K, Colinayo V, Greaser LE, Goldin J, Lusis AJ. Genetic loci determining bone density in mice with diet-induced atherosclerosis. Physiological Genomics. 5: 205-15. PMID 11328966 DOI: 10.1152/Physiolgenomics.2001.5.4.205  0.8
2001 Reddy ST, Wadleigh DJ, Grijalva V, Ng C, Hama S, Gangopadhyay A, Shih DM, Lusis AJ, Navab M, Fogelman AM. Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 542-7. PMID 11304470 DOI: 10.1161/01.Atv.21.4.542  0.348
2001 Navab M, Berliner JA, Subbanagounder G, Hama S, Lusis AJ, Castellani LW, Reddy S, Shih D, Shi W, Watson AD, Van Lenten BJ, Vora D, Fogelman AM. HDL and the inflammatory response induced by LDL-derived oxidized phospholipids. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 481-8. PMID 11304461 DOI: 10.1161/01.Atv.21.4.481  0.324
2001 Hedrick CC, Castellani LW, Wong H, Lusis AJ. In vivo interactions of apoA-II, apoA-I, and hepatic lipase contributing to HDL structure and antiatherogenic functions. Journal of Lipid Research. 42: 563-70. PMID 11290828  0.573
2001 Pajukanta P, Bodnar JS, Sallinen R, Chu M, Airaksinen T, Xiao Q, Castellani LW, Sheth SS, Wessman M, Palotie A, Sinsheimer JS, Demant P, Lusis AJ, Peltonen L. Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 238-45. PMID 11252174 DOI: 10.1007/S003350010265  0.809
2001 Ishikawa K, Sugawara D, Suzuki K, Itabe H, Maruyama Y, Lusis AJ. Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice. Circulation Research. 88: 506-12. PMID 11249874 DOI: 10.1161/01.Res.88.5.506  0.306
2001 Castellani LW, Goto AM, Lusis AJ. Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance. Diabetes. 50: 643-51. PMID 11246886 DOI: 10.2337/Diabetes.50.3.643  0.348
2001 Brennan ML, Anderson MM, Shih DM, Qu XD, Wang X, Mehta AC, Lim LL, Shi W, Hazen SL, Jacob JS, Crowley JR, Heinecke JW, Lusis AJ. Increased atherosclerosis in myeloperoxidase-deficient mice. The Journal of Clinical Investigation. 107: 419-30. PMID 11181641 DOI: 10.1172/Jci8797  0.599
2001 Brennan ML, Gaur A, Pahuja A, Lusis AJ, Reynolds WF. Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 112: 97-105. PMID 11108938 DOI: 10.1016/S0165-5728(00)00392-1  0.57
2001 Krass KL, Lusis AJ. Vitamins at the heart of heart disease? Nature Cell Biology. 3: E115-E115. DOI: 10.1038/35074637  0.757
2000 Villa-Colinayo V, Shi W, Araujo J, Lusis AJ. Genetics of atherosclerosis: the search for genes acting at the level of the vessel wall Current Atherosclerosis Reports. 2: 380-389. PMID 11122769 DOI: 10.1007/S11883-000-0076-2  0.643
2000 Shi W, Wang X, Wang NJ, McBride WH, Lusis AJ. Effect of macrophage-derived apolipoprotein E on established atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2261-6. PMID 11031213 DOI: 10.1161/01.Atv.20.10.2261  0.325
2000 Shi W, Haberland ME, Jien ML, Shih DM, Lusis AJ. Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice. Circulation. 102: 75-81. PMID 10880418 DOI: 10.1161/01.Cir.102.1.75  0.381
2000 Widney DP, Xia YR, Lusis AJ, Smith JB. The murine chemokine CXCL11 (IFN-inducible T cell α chemoattractant) is an IFN-γ- and lipopolysaccharide-inducible glucocorticoid-attenuated response gene expressed in lung and other tissues during endotoxemia Journal of Immunology. 164: 6322-6331. PMID 10843686 DOI: 10.4049/Jimmunol.164.12.6322  0.303
2000 Shi W, Wang NJ, Shih DM, Sun VZ, Wang X, Lusis AJ. Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism. Circulation Research. 86: 1078-84. PMID 10827138 DOI: 10.1161/01.Res.86.10.1078  0.37
2000 Pajukanta P, Bodnar J, Chu M, Xiao Q, Lusis A, Peltonen L. Fine mapping of the human familial combined hyperlipidemia locus on chromosome 1q21-q23 using conserved synteny to the mouse locus on chromosome 3 Atherosclerosis. 151: 236. DOI: 10.1016/S0021-9150(00)81069-2  0.784
2000 Lusis AJ, Mouzeyan A, Choi J, Allayee H, Wang X, Sinsheimer J, Phan J, Castellani LW, Reue K, Davis RC. A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2 Atherosclerosis. 151: 85. DOI: 10.1016/S0021-9150(00)80387-1  0.313
2000 Vaquero E, Gukovskaya A, Brennan M, Lusis A, Holland S, Pandol S. Leukocyte NADPH oxidase but not myeloperoxidase regulates pancreatic trypsin activation in cerulein induced pancreatitis Gastroenterology. 118: A170. DOI: 10.1016/S0016-5085(00)82759-6  0.493
1999 Aouizerat BE, Allayee H, Cantor RM, Dallinga-Thie GM, Lanning CD, De Bruin TWA, Lusis AJ, Rotter JI. Linkage of a candidate gene locus to familial combined hyperlipidemia - Lecithin: Cholesterol acyltransferase on 16q Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2730-2736. PMID 10559018 DOI: 10.1161/01.Atv.19.11.2730  0.329
1999 Aouizerat BE, Allayee H, Cantor RM, Davis RC, Lanning CD, Wen PZ, Dallinga-Thie GM, de Bruin TW, Rotter JI, Lusis AJ. A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11. American Journal of Human Genetics. 65: 397-412. PMID 10417282 DOI: 10.1086/302490  0.378
1999 Aouizerat BE, Allayee H, Bodnar J, Krass KL, Peltonen L, de Bruin TW, Rotter JI, Lusis AJ. Novel genes for familial combined hyperlipidemia. Current Opinion in Lipidology. 10: 113-22. PMID 10327279 DOI: 10.1097/00041433-199904000-00005  0.817
1999 Leitinger N, Watson AD, Hama SY, Ivandic B, Qiao JH, Huber J, Faull KF, Grass DS, Navab M, Fogelman AM, De Beer FC, Lusis AJ, Berliner JA. Role of group II secretory phospholipase A2 in atherosclerosis: 2. Potential involvement of biologically active oxidized phospholipids Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 1291-1298. PMID 10323782 DOI: 10.1161/01.Atv.19.5.1291  0.354
1999 Ivandic B, Castellani LW, Wang XP, Qiao JH, Mehrabian M, Navab M, Fogelman AM, Grass DS, Swanson ME, De Beer MC, De Beer F, Lusis AJ. Role of group II secretory phospholipase A2 in atherosclerosis: 1. Increased atherogenesis and altered lipoproteins in transgenic mice expressing group IIa phospholipase A2 Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 1284-1290. PMID 10323781 DOI: 10.1161/01.Atv.19.5.1284  0.356
1999 Shih PT, Brennan ML, Vora DK, Territo MC, Strahl D, Elices MJ, Lusis AJ, Berliner JA. Blocking very late antigen-4 integrin decreases leukocyte entry and fatty streak formation in mice fed an atherogenic diet. Circulation Research. 84: 345-51. PMID 10024309 DOI: 10.1161/01.Res.84.3.345  0.569
1999 Gu L, Johnson MW, Lusis AJ. Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: Interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 442-453. PMID 9974430 DOI: 10.1161/01.Atv.19.2.442  0.419
1998 Cases S, Smith SJ, Zheng YW, Myers HM, Lear SR, Sande E, Novak S, Collins C, Welch CB, Lusis AJ, Erickson SK, Farese RV. Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis. Proceedings of the National Academy of Sciences of the United States of America. 95: 13018-23. PMID 9789033 DOI: 10.1073/Pnas.95.22.13018  0.341
1998 Cases S, Novak S, Zheng YW, Myers HM, Lear SR, Sande E, Welch CB, Lusis AJ, Spencer TA, Krause BR, Erickson SK, Farese RV. ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization. The Journal of Biological Chemistry. 273: 26755-64. PMID 9756919 DOI: 10.1074/Jbc.273.41.26755  0.371
1998 Shih DM, Gu L, Xia YR, Navab M, Li WF, Hama S, Castellani LW, Furlong CE, Costa LG, Fogelman AM, Lusis AJ. Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis Nature. 394: 284-287. PMID 9685159 DOI: 10.1038/28406  0.365
1998 Allayee H, Aouizerat BE, Cantor RM, Dallinga-Thie GM, Krauss RM, Lanning CD, Rotter JI, Lusis AJ, de Bruin TW. Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype. American Journal of Human Genetics. 63: 577-85. PMID 9683614 DOI: 10.1086/301983  0.361
1998 Jiang Z, Shih DM, Xia YR, Lusis AJ, de Beer FC, de Villiers WJ, van der Westhuyzen DR, de Beer MC. Structure, organization, and chromosomal mapping of the gene encoding macrosialin, a macrophage-restricted protein. Genomics. 50: 199-205. PMID 9653646 DOI: 10.1006/Geno.1998.5327  0.592
1998 Rajavashisth T, Qiao JH, Tripathi S, Tripathi J, Mishra N, Hua M, Wang XP, Loussararian A, Clinton S, Libby P, Lusis A. Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor- deficient mice. The Journal of Clinical Investigation. 101: 2702-10. PMID 9637704 DOI: 10.1172/Jci119891  0.323
1998 Mehrabian M, Wen PZ, Fisler J, Davis RC, Lusis AJ. Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model. The Journal of Clinical Investigation. 101: 2485-96. PMID 9616220 DOI: 10.1172/Jci1748  0.413
1998 Castellani LW, Weinreb A, Bodnar J, Goto AM, Doolittle M, Mehrabian M, Demant P, Lusis AJ. Mapping a gene for combined hyperlipidaemia in a mutant mouse strain Nature Genetics. 18: 374-377. PMID 9537422 DOI: 10.1038/Ng0498-374  0.829
1998 Gitt MA, Xia YR, Atchison RE, Lusis AJ, Barondes SH, Leffler H. Sequence, structure, and chromosomal mapping of the mouse Lgals6 gene, encoding galectin-6. The Journal of Biological Chemistry. 273: 2961-70. PMID 9446609 DOI: 10.1074/Jbc.273.5.2961  0.375
1998 Heinecke JW, Lusis AJ. Paraoxonase-gene polymorphisms associated with coronary heart disease: support for the oxidative damage hypothesis? American Journal of Human Genetics. 62: 20-4. PMID 9443884 DOI: 10.1086/301691  0.36
1998 Meiner VL, Welch CL, Cases S, Myers HM, Sande E, Lusis AJ, Farese RV. Adrenocortical lipid depletion gene (ald) in AKR mice is associated with an acyl-CoA:cholesterol acyltransferase (ACAT) mutation. The Journal of Biological Chemistry. 273: 1064-9. PMID 9422770 DOI: 10.1074/Jbc.273.2.1064  0.397
1997 Klingenspor M, Bodnar J, Welch C, Xia YR, Lusis AJ, Reue K. Localization of ubiquitin gene family members to mouse chromosomes 5, 11, and 18 Mammalian Genome. 8: 789-790. PMID 9321482 DOI: 10.1007/S003359900572  0.793
1997 Lembertas AV, Pérusse L, Chagnon YC, Fisler JS, Warden CH, Purcell-Huynh DA, Dionne FT, Gagnon J, Nadeau A, Lusis AJ, Bouchard C. Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q. The Journal of Clinical Investigation. 100: 1240-7. PMID 9276742 DOI: 10.1172/Jci119637  0.386
1997 Castellani LW, Navab M, Van Lenten BJ, Hedrick CC, Hama SY, Goto AM, Fogelman AM, Lusis AJ. Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles. The Journal of Clinical Investigation. 100: 464-74. PMID 9218525 DOI: 10.1172/Jci119554  0.585
1997 Klingenspor M, Bodnar J, Xia YR, Welch C, Lusis AJ, Reue K. Localization of profilin-1 (Pfn1) and a related sequence (Pfn1-rs) to mouse chromosomes 11 and 15 respectively Mammalian Genome. 8: 539-540. PMID 9196007 DOI: 10.1007/S003359900496  0.776
1997 Navab M, Hama-Levy S, Van Lenten BJ, Fonarow GC, Cardinez CJ, Castellani LW, Brennan ML, Lusis AJ, Fogelman AM, La Du BN. Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio. The Journal of Clinical Investigation. 99: 2005-19. PMID 9109446 DOI: 10.1172/Jci119369  0.525
1997 Machleder D, Ivandic B, Welch C, Castellani L, Reue K, Lusis AJ. Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism Journal of Clinical Investigation. 99: 1406-1419. PMID 9077551 DOI: 10.1172/Jci119300  0.319
1997 Shau H, Kim AT, Hedrick CC, Lusis AJ, Tompkins C, Finney R, Leung DW, Paglia DE. Endogenous natural killer enhancing factor-B increases cellular resistance to oxidative stresses. Free Radical Biology & Medicine. 22: 497-507. PMID 8981042 DOI: 10.1016/S0891-5849(96)00372-3  0.582
1997 Meiner V, Welch C, Cases S, Myers H, Sande E, Lusis A, Farese R. 1.P.107 Adrenocortical lipid depletion gene (ald) in AKR mice is associated with an acyl CoA: cholesterol acyltransferase (ACAT) mutation Atherosclerosis. 134: 39. DOI: 10.1016/S0021-9150(97)88288-3  0.355
1996 Tischfield JA, Xia YR, Shih DM, Klisak I, Chen J, Engle SJ, Siakotos AN, Winstead MV, Seilhamer JJ, Allamand V, Gyapay G, Lusis AJ. Low-molecular-weight, calcium-dependent phospholipase A2 genes are linked and map to homologous chromosome regions in mouse and human. Genomics. 32: 328-33. PMID 8838795 DOI: 10.1006/Geno.1996.0126  0.372
1996 Navab M, Berliner JA, Watson AD, Hama SY, Territo MC, Lusis AJ, Shih DM, Van Lenten BJ, Frank JS, Demer LL, Edwards PA, Fogelman AM. The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture. Arteriosclerosis, Thrombosis, and Vascular Biology. 16: 831-42. PMID 8673557 DOI: 10.1161/01.Atv.16.7.831  0.308
1996 Jonassen T, Marbois BN, Kim L, Chin A, Xia YR, Lusis AJ, Clarke CF. Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. Archives of Biochemistry and Biophysics. 330: 285-9. PMID 8660658 DOI: 10.1006/Abbi.1996.0255  0.37
1996 Ivandic BT, Qiao JH, Machleder D, Liao F, Drake TA, Lusis AJ. A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice Proceedings of the National Academy of Sciences of the United States of America. 93: 5483-5488. PMID 8643601 DOI: 10.1073/Pnas.93.11.5483  0.411
1996 Jiang Y, Yu VC, Buchholz F, O'Connell S, Rhodes SJ, Candeloro C, Xia YR, Lusis AJ, Rosenfeld MG. A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland. The Journal of Biological Chemistry. 271: 10723-30. PMID 8631881 DOI: 10.1074/Jbc.271.18.10723  0.35
1995 Shih DM, Welch C, Lusis AJ. New insights into atherosclerosis from studies with mouse models Molecular Medicine Today. 1: 364-372. PMID 9415182 DOI: 10.1016/S1357-4310(95)93834-6  0.358
1995 Liao F, Andalibi A, Lusis AJ, Fogelman AM. Genetic control of the inflammatory response induced by oxidized lipids The American Journal of Cardiology. 75. PMID 7863978 DOI: 10.1016/0002-9149(95)80015-K  0.355
1995 Berliner JA, Navab M, Fogelman AM, Frank JS, Demer LL, Edwards PA, Watson AD, Lusis AJ. Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. Circulation. 91: 2488-96. PMID 7729036 DOI: 10.1161/01.Cir.91.9.2488  0.347
1995 Warden CH, Fisler JS, Shoemaker SM, Wen PZ, Svenson KL, Pace MJ, Lusis AJ. Identification of four chromosomal loci determining obesity in a multifactorial mouse model. The Journal of Clinical Investigation. 95: 1545-52. PMID 7706460 DOI: 10.1172/Jci117827  0.389
1995 Qiao JH, Fishbein MC, Demer LL, Lusis AJ. Genetic determination of cartilaginous metaplasia in mouse aorta Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2265-2272. PMID 7489252 DOI: 10.1161/01.Atv.15.12.2265  0.392
1994 Hedrick CC, Lusis AJ. Apolipoprotein A-II: A protein in search of a function Canadian Journal of Cardiology. 10: 453-459. PMID 8193990  0.531
1994 Kaufman DL, Xia YR, Keith DE, Newman D, Evans CJ, Lusis AJ. Localization of the δ-opioid receptor gene to mouse chromosome 4 by linkage analysis Genomics. 19: 405-406. PMID 8188281 DOI: 10.1006/Geno.1994.1087  0.324
1994 Qiao JH, Xie PZ, Fishbein MC, Kreuzer J, Drake TA, Demer LL, Lusis AJ. Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 14: 1480-97. PMID 8068611 DOI: 10.1161/01.Atv.14.9.1480  0.371
1994 Marbois BN, Xia YR, Lusis AJ, Clarke CF. Ubiquinone biosynthesis in eukaryotic cells: tissue distribution of mRNA encoding 3,4-dihydroxy-5-polyprenylbenzoate methyltransferase in the rat and mapping of the COQ3 gene to mouse chromosome 4. Archives of Biochemistry and Biophysics. 313: 83-8. PMID 8053692 DOI: 10.1006/Abbi.1994.1362  0.392
1994 Liao F, Andalibi A, Qiao JH, Allayee H, Fogelman AM, Lusis AJ. Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice Journal of Clinical Investigation. 94: 877-884. PMID 8040344 DOI: 10.1172/Jci117409  0.403
1994 Bu X, Warden CH, Xia YR, De Meester C, Puppione DL, Teruya S, Lokensgard B, Daneshmand S, Brown J, Gray RJ, Rotter JI, Lusis AJ. Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci Human Genetics. 93: 639-648. PMID 8005588 DOI: 10.1007/Bf00201563  0.391
1994 Laing AE, Amos CI, DeMeester C, Diep A, Xia YR, Elston RC, Srinivasan SR, Berenson GS, Lusis AJ. Linkage between the APOB gene and serum apoB levels in a large pedigree from the bogalusa heart study Genetic Epidemiology. 11: 29-40. PMID 7912214 DOI: 10.1002/Gepi.1370110104  0.386
1994 Warden CH, Krisans SK, Purcell-Huynh D, Leete LM, Daluiski A, Diep A, Taylor BA, Lusis AJ. Mouse cellular nucleic acid binding proteins: a highly conserved family identified by genetic mapping and sequencing. Genomics. 24: 14-9. PMID 7896269 DOI: 10.1006/Geno.1994.1576  0.35
1994 Hyman RW, Frank S, Warden CH, Daluiski A, Heller R, Lusis AJ. Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice. Biochemical Genetics. 32: 397-407. PMID 7748156 DOI: 10.1007/Bf00566060  0.374
1994 Mehrabian M, Xia YR, Wen PZ, Warden CH, Herschman HR, Lusis AJ. Localization of murine macrophage inducible nitric oxide synthase to mouse chromosome 11. Genomics. 22: 646-7. PMID 7528168 DOI: 10.1006/Geno.1994.1441  0.344
1994 Krauss R, Lusis A, Rotter J. Genetic and metabolic influences on LDL subclasses Atherosclerosis. 109: 351. DOI: 10.1016/0021-9150(94)94397-4  0.374
1994 Hedrick C, Brennan M, Hama S, Navab M, Meidell R, Lusis A. Use of recombinant adenovirus to facilitate gene delivery into human vascular cells in vitro Atherosclerosis. 109: 105. DOI: 10.1016/0021-9150(94)93433-9  0.602
1993 Fisler JS, Warden CH, Pace MJ, Lusis AJ. BSB: a new mouse model of multigenic obesity. Obesity Research. 1: 271-80. PMID 16353357 DOI: 10.1002/J.1550-8528.1993.Tb00621.X  0.363
1993 Andalibi A, Diep A, Quon D, Mohandas T, Taylor BA, Lusis AJ. Mapping of multiple mouse loci related to the farnesyl pyrophosphate synthetase gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 211-9. PMID 8499655 DOI: 10.1007/Bf00417565  0.392
1993 Shieh BH, Sparkes RS, Gaynor RB, Lusis AJ. Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23. Genomics. 16: 266-8. PMID 8486371 DOI: 10.1006/Geno.1993.1174  0.326
1993 Wen PZ, Warden C, Fletcher BS, Kujubu DA, Herschman HR, Lusis AJ. Chromosomal organization of the inducible and constitutive prostaglandin synthase/cyclooxygenase genes in mouse. Genomics. 15: 458-60. PMID 8449520 DOI: 10.1006/Geno.1993.1091  0.353
1993 Mehrabian M, Gitt MA, Sparkes RS, Leffler H, Barondes SH, Lusis AJ. Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13. Genomics. 15: 418-20. PMID 8449510 DOI: 10.1006/Geno.1993.1078  0.307
1993 Mehrabian M, Qiao JH, Hyman R, Ruddle D, Laughton C, Lusis AJ. Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 13: 1-10. PMID 8422330  0.315
1993 Gaynor RB, Shieh BH, Klisak I, Sparkes RS, Lusis AJ. Localization of the transcription factor SP1 gene to human chromosome 12q12-->q13.2. Cytogenetics and Cell Genetics. 64: 210-2. PMID 8404040 DOI: 10.1159/000133578  0.332
1993 Xia YR, Klisak I, Sparkes RS, Oram J, Lusis AJ. Localization of the gene for high-density lipoprotein binding protein (HDLBP) to human chromosome 2q37 Genomics. 16: 524-525. PMID 8390966 DOI: 10.1006/Geno.1993.1221  0.328
1993 Hedrick CC, Castellani LW, Warden CH, Puppione DL, Lusis AJ. Influence of mouse apolipoprotein A-II on plasma lipoproteine in transgenic mice Journal of Biological Chemistry. 268: 20676-20682. PMID 8376417  0.564
1993 Warden CH, Hedrick CC, Qiao JH, Castellani LW, Lusis AJ. Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II Science. 261: 469-472. PMID 8332912 DOI: 10.1126/Science.8332912  0.62
1993 Warden CH, Mehrabian M, He Ky, Yoon MY, Diep A, Xia YR, Wen PZ, Svenson KL, Sparkes RS, Lusis AJ. Linkage Mapping of 40 Randomly Isolated Liver cDNA Clones in the Mouse Genomics. 18: 295-307. PMID 8288233 DOI: 10.1006/Geno.1993.1469  0.377
1993 Heiba IM, DeMeester CA, Xia YR, Diep A, George VT, Amos CI, Srinivasan SR, Berenson GS, Elston RC, Lusis AJ. Genetic contributions to quantitative lipoprotein traits associated with coronary artery disease: Analysis of a large pedigree from the bogalusa heart study American Journal of Medical Genetics. 47: 875-883. PMID 8279486 DOI: 10.1002/Ajmg.1320470615  0.315
1993 Lusis AJ, Navab M. Lipoprotein oxidation and gene expression in the artery wall. New opportunities for pharmacologic intervention in atherosclerosis Biochemical Pharmacology. 46: 2119-2126. PMID 8274144 DOI: 10.1016/0006-2952(93)90599-R  0.302
1993 Xia YR, Bachinsky DR, Smith JA, McCluskey RT, Warden CH, Lusis AJ. Mapping of the Glycoprotein 330 (Gp330) Gene to Mouse Chromosome 2 Genomics. 17: 780-781. PMID 8244399 DOI: 10.1006/Geno.1993.1408  0.366
1993 Johnson B, Brooks BA, Heinzmann C, Diep A, Mohandas T, Sparkes RS, Reyes H, Hoffman E, Lange E, Gatti A, Xia YR, Lusis AJ, Hankinson O. The Ah Receptor Nuclear Translocator Gene (ARNT) Is Located on q21 of Human Chromosome 1 and on Mouse Chromosome 3 near Cf-3 Genomics. 17: 592-598. PMID 8244375 DOI: 10.1006/Geno.1993.1377  0.361
1993 Qiao JH, Welch CL, Xie PZ, Fishbein MC, Lusis AJ. Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice association with aortic fatty streak development Journal of Clinical Investigation. 92: 2386-2393. PMID 8227355 DOI: 10.1172/Jci116844  0.44
1993 Lusis AJ. The mouse model for atherosclerosis Trends in Cardiovascular Medicine. 3: 135-143. DOI: 10.1016/1050-1738(93)90014-W  0.434
1992 Diep A, Li C, Klisak I, Mohandas T, Sparkes RS, Gaynor R, Lusis AJ. Assignment of the gene for cyclic AMP-response element binding protein 2 (CREB2) to human chromosome 2q24.1-q32. Genomics. 11: 1161-3. PMID 1838349 DOI: 10.1016/0888-7543(91)90047-I  0.376
1992 Li C, Lusis AJ, Sparkes R, Tran SM, Gaynor R. Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein HTLF Genomics. 13: 658-664. PMID 1639393 DOI: 10.1016/0888-7543(92)90138-I  0.354
1992 Bork RW, Svenson KL, Mehrabian M, Lusis AJ, Fogelman AM, Edwards PA. Mechanisms controlling competence gene expression in murine fibroblasts stimulated with minimally modified LDL. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 12: 800-6. PMID 1616905 DOI: 10.1161/01.Atv.12.7.800  0.321
1992 Warden CH, Diep A, Taylor BA, Lusis AJ. Localization of the gene for apolipoprotein D on mouse chromosome 16. Genomics. 12: 851-2. PMID 1572665 DOI: 10.1016/0888-7543(92)90325-M  0.341
1992 Shieh BH, Xia Y, Sparkes RS, Klisak I, Lusis AJ, Nicoll DA, Philipson KD. Mapping of the gene for the cardiac sarcolemmal Na(+)-Ca2+ exchanger to human chromosome 2p21-p23. Genomics. 12: 616-7. PMID 1559714 DOI: 10.1016/0888-7543(92)90459-6  0.319
1992 MacLaren DC, O'Connor CM, Xia Yr, Mehrabian M, Klisak I, Sparkes RS, Clarke S, Lusis AJ. The l-isoaspartyl/d-aspartyl protein methyltransferase gene (PCMT1) maps to human chromosome 6q22.3-6q24 and the syntenic region of mouse chromosome 10 Genomics. 14: 852-856. PMID 1478665 DOI: 10.1016/S0888-7543(05)80104-1  0.37
1992 Garcia JA, Ou SH, Wu F, Lusis AJ, Sparkes RS, Gaynor RB. Cloning and chromosomal mapping of a human immunodeficiency virus 1 "TATA" element modulatory factor. Proceedings of the National Academy of Sciences of the United States of America. 89: 9372-6. PMID 1409643 DOI: 10.1073/Pnas.89.20.9372  0.321
1992 Cohen JC, Cali JJ, Jelinek DF, Mehrabian M, Sparkes RS, Lusis AJ, Russell DW, Hobbs HH. Cloning of the human cholesterol 7 alpha-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12. Genomics. 14: 153-61. PMID 1358792 DOI: 10.1016/S0888-7543(05)80298-8  0.376
1992 Warden CH, Daluiski A, Lusis AJ. Identification of New Genes Contributing to Atherosclerosis: The Mapping of Genes Contributing to Complex Disorders in Animal Models Monographs in Human Genetics. 14: 419-441. DOI: 10.1159/000421524  0.368
1992 Mehrabian M, Lusis AJ. Genetic markers for studies of atherosclerosis and related risk factors Monographs in Human Genetics. 14: 363-418. DOI: 10.1159/000421523  0.317
1992 Lusis AJ, Castellani LW, Fisler JS. Fitting pieces from studies of animal models into the puzzle of atherosclerosis Current Opinion in Lipidology. 3: 143-150. DOI: 10.1097/00041433-199204000-00011  0.338
1991 Davis RC, Xia YR, Mohandas T, Schotz MC, Lusis AJ. Assignment of the human pancreatic colipase gene to chromosome 6p21.1 to pter. Genomics. 10: 262-5. PMID 2045105 DOI: 10.1016/0888-7543(91)90509-D  0.335
1991 Liao F, Berliner JA, Mehrabian M, Navab M, Demer LL, Lusis AJ, Fogelman AM. Minimally modified low density lipoprotein Is biologically active in vivo in mice Journal of Clinical Investigation. 87: 2253-2257. PMID 2040705 DOI: 10.1172/Jci115261  0.303
1991 Gaynor RB, Muchardt C, Diep A, Mohandas TK, Sparkes RS, Lusis AJ. Localization of the zinc finger DNA-binding protein HIV-EP1/MBP-1/PRDII-BF1 to human chromosome 6p22.3-p24 Genomics. 9: 758-761. PMID 2037300 DOI: 10.1016/0888-7543(91)90371-K  0.331
1991 Dowbenko DJ, Diep A, Taylor BA, Lusis AJ, Lasky LA. Characterization of the murine homing receptor gene reveals correspondence between protein domains and coding exons. Genomics. 9: 270-7. PMID 2004776 DOI: 10.1016/0888-7543(91)90252-A  0.321
1991 Mehrabian M, Sparkes RS, Mohandas T, Fogelman AM, Lusis AJ. Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1 Genomics. 9: 200-203. PMID 2004761 DOI: 10.1016/0888-7543(91)90239-B  0.345
1991 Gaynor RB, Muchardt C, Xia YR, Klisak I, Mohandas T, Sparkes RS, Lusis AJ. Localization of the gene for the DNA-binding protein AP-2 to human chromosome 6p22.3-pter. Genomics. 10: 1100-2. PMID 1916817 DOI: 10.1016/0888-7543(91)90209-W  0.344
1991 Davis RC, Diep A, Hunziker W, Klisak I, Mohandas T, Schotz MC, Sparkes RS, Lusis AJ. Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24-q26. Genomics. 11: 1164-6. PMID 1783385 DOI: 10.1016/0888-7543(91)90048-J  0.329
1991 Taylor AK, Zambaux JL, Klisak I, Mohandas T, Sparkes RS, Schotz MC, Lusis AJ. Carboxyl ester lipase: a highly polymorphic locus on human chromosome 9qter. Genomics. 10: 425-31. PMID 1676983 DOI: 10.1016/0888-7543(91)90328-C  0.394
1991 Heizmann C, Kirchgessner T, Kwiterovich PO, Ladias JA, Derby C, Antonarakis SE, Lusis AJ. DNA polymorphism haplotypes of the human lipoprotein lipase gene: possible association with high density lipoprotein levels Human Genetics. 86: 578-584. PMID 1673959 DOI: 10.1007/Bf00201544  0.379
1990 Lusis AJ, Rajavashisth TB, Klisak I, Heinzmann C, Mohandas T, Sparkes RS. Mapping of the gene for CNBP, a finger protein, to human chromosome 3q13.3-q24 Genomics. 8: 411-414. PMID 2249857 DOI: 10.1016/0888-7543(90)90303-C  0.321
1990 Taylor AK, Klisak I, Mohandas T, Sparkes RS, Li C, Gaynor R, Lusis AJ. Assignment of the human gene for CREB1 to chromosome 2q32.3-q34. Genomics. 7: 416-21. PMID 2142119 DOI: 10.1016/0888-7543(90)90176-U  0.355
1989 Frank SL, Klisak I, Sparkes RS, Lusis AJ. A gene homologous to plasminogen located on human chromosome 2q11-p11 Genomics. 4: 449-451. PMID 2714803 DOI: 10.1016/0888-7543(89)90356-X  0.306
1989 Seilhamer JJ, Randall TL, Johnson LK, Heinzmann C, Klisak I, Sparkes RS, Lusis AJ. Novel gene exon homologous to pancreatic phospholipase A2: sequence and chromosomal mapping of both human genes. Journal of Cellular Biochemistry. 39: 327-37. PMID 2708461 DOI: 10.1002/Jcb.240390312  0.336
1989 Frank SL, Taylor BA, Lusis AJ. Linkage of the mouse LDL receptor gene on chromosome 9. Genomics. 5: 646-8. PMID 2575592 DOI: 10.1016/0888-7543(89)90037-2  0.423
1989 Heinzmann C, Rajavashisth T, Rotter J, Lusis AJ. Kpnl RFLP for the human CSF-1 gene Nucleic Acids Research. 17: 6425. PMID 2570404 DOI: 10.1093/Nar/17.15.6425  0.319
1989 Lusis AJ, Sparkes RS. Chromosomal Organization of Genes Involved in Plasma Lipoprotein Metabolism: Human and Mouse ‘Fat Maps’ Monographs in Human Genetics. 12: 79-94. DOI: 10.1159/000416889  0.434
1988 Sparkes RS, Zollman S, Klisak I, Kirchgessner TG, Komaromy MC, Mohandas T, Schotz MC, Lusis AJ. Human genes involved in lipolysis of plasma lipoproteins: mapping of loci for lipoprotein lipase to 8p22 and hepatic lipase to 15q21. Genomics. 1: 138-44. PMID 3692485 DOI: 10.1016/0888-7543(87)90005-X  0.404
1988 Lusis AJ, Zollman S, Sparkes RS, Klisak I, Mohandas T, Drayna D, Lawn RM. Assignment of the human gene for cholesteryl ester transfer protein to chromosome 16q12-16q21. Genomics. 1: 232-5. PMID 3446583 DOI: 10.1016/0888-7543(87)90049-8  0.392
1988 Frank SL, Klisak I, Sparkes RS, Mohandas T, Tomlinson JE, McLean JW, Lawn RM, Lusis AJ. The apolipoprotein(a) gene resides on human chromosome 6q26-27, in close proximity to the homologous gene for plasminogen Human Genetics. 79: 352-356. PMID 3410459 DOI: 10.1007/Bf00282175  0.406
1988 Lusis AJ. Genetic factors affecting blood lipoproteins: the candidate gene approach Journal of Lipid Research. 29: 397-429. PMID 3292686  0.358
1988 Heinzmann C, Ladias J, Antonarakis S, Diep A, Schotz M, Lusis AJ. Two polymorphisms for the human hepatic lipase (HL) gene Nucleic Acids Research. 16: 4739. PMID 2454457 DOI: 10.1093/Nar/16.10.4739  0.326
1987 Paigen B, Mitchell D, Reue K, Morrow A, Lusis AJ, LeBoeuf RC. Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice Proceedings of the National Academy of Sciences of the United States of America. 84: 3763-3767. PMID 3473481 DOI: 10.1073/Pnas.84.11.3763  0.448
1987 Lusis AJ, Taylor BA, Quon D, Zollman S, LeBoeuf RC. Genetic factors controlling structure and expression of apolipoproteins B and E in mice. The Journal of Biological Chemistry. 262: 7594-604. PMID 3034900  0.363
1987 Heinzmann C, Ladias J, Antonarakis S, Kirchgessner T, Schotz M, Lusis AJ. RFLP for the human lipoprotein lipase (LPL) gene: HindIII Nucleic Acids Research. 15: 6763. PMID 2888089 DOI: 10.1093/Nar/15.16.6763  0.36
1986 Lusis AJ, LeBoeuf RC. Genetic control of plasma lipid transport: Mouse model Methods in Enzymology. 877-894. PMID 3724533 DOI: 10.1016/0076-6879(86)28112-4  0.433
1986 Lusis AJ, Heinzmann C, Sparkes RS, Scott J, Knott TJ, Geller R, Sparkes MC, Mohandas T. Regional mapping of human chromosome 19: organization of genes for plasma lipid transport (APOC1, -C2, and -E and LDLR) and the genes C3, PEPD, and GPI. Proceedings of the National Academy of Sciences of the United States of America. 83: 3929-33. PMID 3459164 DOI: 10.1073/Pnas.83.11.3929  0.398
1986 Mohandas T, Heinzmann C, Sparkes RS, Wasmuth J, Edwards P, Lusis AJ. Assignment of human 3-hydroxy-3-methylglutaryl coenzyme A reductase gene to q13 → q23 region of chromosome 5 Somatic Cell and Molecular Genetics. 12: 89-94. PMID 3456176 DOI: 10.1007/Bf01560731  0.346
1986 Mehrabian M, Sparkes RS, Mohandas T, Klisak IJ, Schumaker VN, Heinzmann C, Zollman S, Ma YH, Lusis AJ. Human apolipoprotein B: chromosomal mapping and DNA polymorphisms of hepatic and intestinal species. Somatic Cell and Molecular Genetics. 12: 245-54. PMID 3012797 DOI: 10.1007/Bf01570783  0.389
1985 Lazar GS, Quon DH, Lusis AJ. A gene-controlling response of bone marrow progenitor cells to granulocyte-macrophage colony stimulating factors Journal of Cellular Physiology. 124: 293-298. PMID 3876341 DOI: 10.1002/Jcp.1041240219  0.325
1983 Lusis AJ, Chapman VM, Wangenstein RW, Paigen K. Trans-acting temporal locus within the beta-glucuronidase gene complex. Proceedings of the National Academy of Sciences of the United States of America. 80: 4398-402. PMID 6576346 DOI: 10.1073/Pnas.80.14.4398  0.316
1983 O'Donnell KA, Lusis AJ. Genetic evidence that the multiple apolipoprotein A-1 isoforms are encoded by a common structural gene Biochemical and Biophysical Research Communications. 114: 275-281. PMID 6411081 DOI: 10.1016/0006-291X(83)91624-8  0.372
1983 Lusis AJ, Taylor BA, Wangenstein RW, LeBoeuf RC. Genetic control of lipid transport in mice. II. Genes controlling structure of high density lipoproteins. The Journal of Biological Chemistry. 258: 5071-8. PMID 6403543  0.337
1980 Hjorth JP, Lusis AJ, Nielsen JT. Multiple structural genes for mouse amylase. Biochemical Genetics. 18: 281-302. PMID 6160849 DOI: 10.1007/Bf00484242  0.378
1977 Lusis AJ, Tomino S, Paigen K. Inheritance in mice of the membrane anchor protein egasyn: The Eg locus determines egasyn levels Biochemical Genetics. 15: 115-122. PMID 849245 DOI: 10.1007/Bf00484554  0.339
1976 Lusis AJ, West JD. X-linked inheritance of a structural gene for α-galactosidease in Mus musculus Biochemical Genetics. 14: 849-855. PMID 1008807 DOI: 10.1007/Bf00485346  0.308
1975 Lusis AJ, Paigen K. Genetic determination of the α-galactosidase developmental program in mice Cell. 6: 371-378. PMID 212204 DOI: 10.1016/0092-8674(75)90186-5  0.331
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