Aldons J. Lusis - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Immunology, Microbiology Biology

446 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Parker BL, Calkin AC, Seldin MM, Keating MF, Tarling EJ, Yang P, Moody SC, Liu Y, Zerenturk EJ, Needham EJ, Miller ML, Clifford BL, Morand P, Watt MJ, Meex RCR, ... ... Lusis AJ, et al. An integrative systems genetic analysis of mammalian lipid metabolism. Nature. PMID 30814737 DOI: 10.1038/s41586-019-0984-y  0.48
2019 Shih DM, Meng Y, Sallam T, Vergnes L, Shu ML, Reue K, Tontonoz P, Fogelman AM, Lusis AJ, Reddy ST. PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. Antioxidants (Basel, Switzerland). 8. PMID 30641857 DOI: 10.3390/antiox8010019  0.64
2019 Norheim F, Hasin-Brumshtein Y, Vergnes L, Chella Krishnan K, Pan C, Seldin MM, Hui ST, Mehrabian M, Zhou Z, Gupta S, Parks BW, Walch A, Reue K, Hofmann SM, Arnold AP, ... Lusis AJ, et al. Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits. Cell Metabolism. PMID 30639359 DOI: 10.1016/j.cmet.2018.12.013  0.56
2019 Pamir N, Pan C, Plubell DL, Hutchins PM, Tang C, Wimberger J, Irwin A, Vallim TQA, Heinecke JW, Lusis AJ. Genetic control of the mouse HDL proteome defines HDL traits, function, and heterogeneity. Journal of Lipid Research. PMID 30622162 DOI: 10.1194/jlr.M090555  0.48
2019 Seldin MM, Lusis AJ. Systems-based approaches for investigation of inter-tissue communication. Journal of Lipid Research. PMID 30617149 DOI: 10.1194/jlr.S090316  0.36
2019 Ma F, Fuqua BK, Hasin Y, Yukhtman C, Vulpe CD, Lusis AJ, Pellegrini M. A comparison between whole transcript and 3' RNA sequencing methods using Kapa and Lexogen library preparation methods. Bmc Genomics. 20: 9. PMID 30616562 DOI: 10.1186/s12864-018-5393-3  0.68
2018 Martin LJ, Meng Q, Blencowe M, Lagarrigue S, Xiao S, Pan C, Wier J, Temple WC, Devaskar SU, Lusis AJ, Yang X. Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring. Frontiers in Genetics. 9: 642. PMID 30619467 DOI: 10.3389/fgene.2018.00642  0.84
2018 Moore TM, Zhou Z, Cohn W, Norheim F, Lin AJ, Kalajian N, Strumwasser AR, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Shirihai O, van der Bliek AM, ... ... Lusis AJ, et al. The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle. Molecular Metabolism. PMID 30591411 DOI: 10.1016/j.molmet.2018.11.012  0.48
2018 Lang JM, Pan C, Cantor RM, Tang WHW, Garcia-Garcia JC, Kurtz I, Hazen SL, Bergeron N, Krauss RM, Lusis AJ. Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome. Mbio. 9. PMID 30538180 DOI: 10.1128/mBio.01604-18  0.48
2018 Bond ST, Moody SC, Liu Y, Civelek M, Villanueva CJ, Gregorevic P, Kingwell BA, Hevener AL, Lusis AJ, Henstridge DC, Calkin AC, Drew BG. The E3 ligase March5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes American Journal of Physiology. Endocrinology and Metabolism. PMID 30512991 DOI: 10.1152/ajpendo.00394.2018  0.48
2018 Kasahara K, Krautkramer KA, Org E, Romano KA, Kerby RL, Vivas EI, Mehrabian M, Denu JM, Bäckhed F, Lusis AJ, Rey FE. Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model. Nature Microbiology. PMID 30397344 DOI: 10.1038/s41564-018-0272-x  0.56
2018 Pirie E, Ray S, Pan C, Fu W, Powers AF, Polikoff D, Miller CM, Kudrna KM, Harris EN, Lusis AJ, Crooke RM, Lee RG. Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1. Plos Genetics. 14: e1007732. PMID 30372444 DOI: 10.1371/journal.pgen.1007732  0.48
2018 Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, Tang WHW, Lusis AJ, Rey FE, Fischbach MA, Hazen SL. Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential. Circulation Research. 123: 1164-1176. PMID 30359185 DOI: 10.1161/CIRCRESAHA.118.313142  0.44
2018 Thompson MJ, Chwiałkowska K, Rubbi L, Lusis AJ, Davis RC, Srivastava A, Korstanje R, Churchill GA, Horvath S, Pellegrini M. A multi-tissue full lifespan epigenetic clock for mice. Aging. PMID 30348905 DOI: 10.18632/aging.101590  0.68
2018 Kurt Z, Barrere-Cain R, LaGuardia J, Mehrabian M, Pan C, Hui ST, Norheim F, Zhou Z, Hasin Y, Lusis AJ, Yang X. Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease. Biology of Sex Differences. 9: 46. PMID 30343673 DOI: 10.1186/s13293-018-0205-7  0.84
2018 Rees CM, Yang JH, Santolini M, Lusis AJ, Weiss JN, Karma A. The Ca transient as a feedback sensor controlling cardiomyocyte ionic conductances in mouse populations. Elife. 7. PMID 30251624 DOI: 10.7554/eLife.36717  0.32
2018 Lin LY, Chun-Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, ... ... Lusis AJ, et al. Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure. G3 (Bethesda, Md.). PMID 30201759 DOI: 10.1534/g3.118.200655  0.48
2018 Chella Krishnan K, Mehrabian M, Lusis AJ. Sex differences in metabolism and cardiometabolic disorders. Current Opinion in Lipidology. 29: 404-410. PMID 30156571 DOI: 10.1097/MOL.0000000000000536  0.56
2018 Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, et al. Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nature Communications. 9: 3472. PMID 30135520 DOI: 10.1038/s41467-018-05849-3  0.48
2018 Roberts AB, Gu X, Buffa JA, Hurd AG, Wang Z, Zhu W, Gupta N, Skye SM, Cody DB, Levison BS, Barrington WT, Russell MW, Reed JM, Duzan A, Lang JM, ... ... Lusis AJ, et al. Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential. Nature Medicine. PMID 30082863 DOI: 10.1038/s41591-018-0128-1  0.44
2018 Erbilgin A, Seldin MM, Wu X, Mehrabian M, Zhou Z, Qi H, Dabirian KS, Sevag Packard RR, Hsieh W, Bensinger SJ, Sinha S, Lusis AJ. Transcription Factor Deficiency Reduces Atherosclerosis and Promotes Macrophage Apoptosis in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 30026271 DOI: 10.1161/ATVBAHA.118.311266  0.8
2018 Park S, Ranjbarvazirj S, Lay FD, Zhao P, Miller MJ, Dhaliwal JS, Huertas-Vazquez A, Wu X, Qiao R, Soffer JM, Mikkola HKA, Lusis AJ, Ardehali R. Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. Circulation. PMID 29950403 DOI: 10.1161/CIRCULATIONAHA.118.035420  0.8
2018 Hui ST, Kurt Z, Tuominen I, Norheim F, Davis RC, Pan C, Dirks DL, Magyar CE, French SW, Chella Krishnan K, Sabir S, Campos-Pérez F, Méndez-Sánchez N, Macías-Kauffer L, León-Mimila P, ... ... Lusis AJ, et al. The Genetic Architecture of Diet-induced Hepatic Fibrosis in Mice. Hepatology (Baltimore, Md.). PMID 29907965 DOI: 10.1002/hep.30113  0.84
2018 Hitzel J, Lee E, Zhang Y, Bibli SI, Li X, Zukunft S, Pflüger B, Hu J, Schürmann C, Vasconez AE, Oo JA, Kratzer A, Kumar S, Rezende F, Josipovic I, ... ... Lusis AJ, et al. Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Nature Communications. 9: 2292. PMID 29895827 DOI: 10.1038/s41467-018-04602-0  0.84
2018 Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, ... ... Lusis AJ, et al. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics. PMID 29893869 DOI: 10.1093/hmg/ddy205  0.68
2018 Norheim F, Bjellaas T, Hui ST, Chella Krishnan K, Lee J, Gupta S, Pan C, Hasin-Brumshtein Y, Parks BW, Li D, Bui H, Mosier M, Wu Y, Huertas-Vazquez A, Hazen SW, ... ... Lusis AJ, et al. Genetic, dietary, and sex-specific regulation of hepatic ceramides and relationship between hepatic ceramides and insulin resistance. Journal of Lipid Research. PMID 29739864 DOI: 10.1194/jlr.M081398  0.56
2018 Seldin MM, Koplev S, Rajbhandari P, Vergnes L, Rosenberg GM, Meng Y, Pan C, Phuong TMN, Gharakhanian R, Che N, Mäkinen S, Shih DM, Civelek M, Parks BW, Kim ED, ... ... Lusis AJ, et al. A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism. Cell Metabolism. 27: 1138-1155.e6. PMID 29719227 DOI: 10.1016/j.cmet.2018.03.015  0.68
2018 Yu J, Seldin MM, Fu K, Li S, Lam L, Wang P, Wang Y, Huang D, Nguyen TL, Wei B, Kulkarni RP, Di Carlo D, Teitell M, Pellegrini M, Lusis AJ, et al. Topological Arrangement of Cardiac Fibroblasts Regulates Cellular Plasticity. Circulation Research. PMID 29691232 DOI: 10.1161/CIRCRESAHA.118.312589  0.68
2018 Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, et al. Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nature Communications. 9: 1512. PMID 29666371 DOI: 10.1038/s41467-018-03554-9  0.48
2018 Hiyari S, Green E, Pan C, Lari S, Davar M, Davis R, Camargo PM, Tetradis S, Lusis AJ, Pirih FQ. Genome-Wide Association Study Identifies Cxcl Family Members as Partial Mediators of LPS-induced Periodontitis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29637625 DOI: 10.1002/jbmr.3440  0.48
2018 Small KS, Todorčević M, Civelek M, El-Sayed Moustafa JS, Wang X, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, ... ... Lusis AJ, et al. Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. Nature Genetics. 50: 572-580. PMID 29632379 DOI: 10.1038/s41588-018-0088-x  0.8
2018 Orozco LD, Farrell C, Hale C, Rbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, ... Lusis AJ, et al. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics. PMID 29566149 DOI: 10.1093/hmg/ddy093  0.68
2018 Santolini M, Romay MC, Yukhtman CL, Rau CD, Ren S, Saucerman JJ, Wang JJ, Weiss JN, Wang Y, Lusis AJ, Karma A. A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure. Npj Systems Biology and Applications. 4: 12. PMID 29507758 DOI: 10.1038/s41540-018-0046-3  0.48
2018 Chella Krishnan K, Kurt Z, Barrere-Cain R, Sabir S, Das A, Floyd R, Vergnes L, Zhao Y, Che N, Charugundla S, Qi H, Zhou Z, Meng Y, Pan C, Seldin MM, ... ... Lusis AJ, et al. Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease. Cell Systems. PMID 29361464 DOI: 10.1016/j.cels.2017.12.006  0.84
2018 Barrington WT, Salvador AC, Hartiala JA, De Caterina R, Kohlmeier M, Martinez JA, Kreutzer CB, Heber D, Lusis AJ, Li Z, Allayee H. Proceedings of the 11th Congress of the International Society of Nutrigenetics and Nutrigenomics (ISNN 2017). Journal of Nutrigenetics and Nutrigenomics. 10: 155-162. PMID 29339647 DOI: 10.1159/000485799  0.48
2018 Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T, Wang B, Sandhu J, Seldin MM, Lusis AJ, Fong LG, Katz M, Lee R, Young SG, et al. IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure. Cell. 172: 218-233.e17. PMID 29249357 DOI: 10.1016/j.cell.2017.11.019  0.48
2017 Nakano H, Minami I, Braas D, Pappoe H, Wu X, Sagadevan A, Vergnes L, Fu K, Morselli M, Dunham C, Ding X, Stieg AZ, Gimzewski JK, Pellegrini M, Clark PM, ... ... Lusis AJ, et al. Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. Elife. 6. PMID 29231167 DOI: 10.7554/eLife.29330  0.8
2017 Shu L, Chan KHK, Zhang G, Huan T, Kurt Z, Zhao Y, Codoni V, Trégouët DA, Yang J, Wilson JG, Luo X, Levy D, Lusis AJ, Liu S, et al. Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States. Plos Genetics. 13: e1007040. PMID 28957322 DOI: 10.1371/journal.pgen.1007040  0.84
2017 McLachlan S, Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E, Vulpe CD. Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but don't predict tissue iron levels in inbred mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00307.2016. PMID 28798083 DOI: 10.1152/ajpgi.00307.2016  0.44
2017 Kim S, Yang L, Kim S, Lee RG, Graham MJ, Berliner JA, Lusis AJ, Cai L, Temel RE, Rateri DL, Lee S. Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development. Plos One. 12: e0182566. PMID 28792970 DOI: 10.1371/journal.pone.0182566  0.36
2017 Patterson M, Barske L, Van Handel B, Rau CD, Gan P, Sharma A, Parikh S, Denholtz M, Huang Y, Yamaguchi Y, Shen H, Allayee H, Crump JG, Force TI, Lien CL, ... ... Lusis AJ, et al. Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nature Genetics. PMID 28783163 DOI: 10.1038/ng.3929  0.48
2017 Cannon ME, Duan Q, Wu Y, Zeynalzadeh M, Xu Z, Kangas AJ, Soininen P, Ala-Korpela M, Civelek M, Lusis AJ, Kuusisto J, Collins FS, Boehnke M, Tang H, Laakso M, et al. Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus. G3 (Bethesda, Md.). PMID 28754724 DOI: 10.1534/g3.117.300088  0.48
2017 Buscher K, Ehinger E, Gupta P, Pramod AB, Wolf D, Tweet G, Pan C, Mills CD, Lusis AJ, Ley K. Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival. Nature Communications. 8: 16041. PMID 28737175 DOI: 10.1038/ncomms16041  0.48
2017 Daugherty A, Tall AR, Daemen MJAP, Falk E, Fisher EA, García-Cardeña G, Lusis AJ, Owens AP, Rosenfeld ME, Virmani R. Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28729366 DOI: 10.1161/ATV.0000000000000062  0.32
2017 Daugherty A, Tall AR, Daemen MJAP, Falk E, Fisher EA, García-Cardeña G, Lusis AJ, Owens AP, Rosenfeld ME, Virmani R. Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association. Circulation Research. PMID 28729353 DOI: 10.1161/RES.0000000000000169  0.32
2017 Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng Y, ... ... Lusis AJ, et al. The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. Cell Reports. 20: 279. PMID 28683320 DOI: 10.1016/j.celrep.2017.06.053  0.68
2017 Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng Y, ... ... Lusis AJ, et al. The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. Cell Reports. 19: 2451-2461. PMID 28636934 DOI: 10.1016/j.celrep.2017.05.077  0.68
2017 Mukherjee P, Hough G, Chattopadhyay A, Navab M, Fogelman HR, Meriwether D, Williams K, Bensinger S, Moller T, Faull KF, Lusis AJ, Iruela-Arispe L, Bostrom KI, Tontonoz P, Reddy ST, et al. Transgenic Tomatoes Expressing the 6F Peptide and Ezetimibe Prevent Diet-induced Increases of Interferon-β and Cholesterol 25-hydroxylase in Jejunum. Journal of Lipid Research. PMID 28592401 DOI: 10.1194/jlr.M076554  0.56
2017 Kessler T, Wobst J, Wolf B, Eckhold J, Vilne B, Hollstein R, von Ameln S, Dang TA, Sager HB, Rumpf PM, Aherrahrou R, Kastrati A, Bjoerkegren JLM, Erdmann J, Lusis AJ, et al. Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus. Circulation. PMID 28487391 DOI: 10.1161/CIRCULATIONAHA.116.024152  0.48
2017 Org E, Blum Y, Kasela S, Mehrabian M, Kuusisto J, Kangas AJ, Soininen P, Wang Z, Ala-Korpela M, Hazen SL, Laakso M, Lusis AJ. Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort. Genome Biology. 18: 70. PMID 28407784 DOI: 10.1186/s13059-017-1194-2  0.56
2017 Civelek M, Wu Y, Pan C, Raulerson CK, Ko A, He A, Tilford C, Saleem NK, Stančáková A, Scott LJ, Fuchsberger C, Stringham HM, Jackson AU, Narisu N, Chines PS, ... ... Lusis AJ, et al. Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits. American Journal of Human Genetics. 100: 428-443. PMID 28257690 DOI: 10.1016/j.ajhg.2017.01.027  0.48
2017 Seldin MM, Kim ED, Romay MC, Li S, Rau CD, Wang JJ, Chella Krishnan K, Wang Y, Deb A, Lusis AJ. Systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00068.2016. PMID 28235788 DOI: 10.1152/ajpheart.00068.2016  0.48
2017 Baliga NS, Björkegren JL, Boeke JD, Boutros M, Crawford NP, Dudley AM, Farber CR, Jones A, Levey AI, Lusis AJ, Mak HC, Nadeau JH, Noyes MB, Petretto E, Seyfried NT, et al. The State of Systems Genetics in 2017. Cell Systems. 4: 7-15. PMID 28125793 DOI: 10.1016/j.cels.2017.01.005  0.32
2017 Laakso M, Kuusisto J, Stancakova A, Kuulasmaa T, Pajukanta P, Lusis AJ, Collins FS, Mohlke K, Boehnke M. METabolic Syndrome In Men (METSIM) Study: a resource for studies of metabolic and cardiovascular diseases. Journal of Lipid Research. PMID 28119442 DOI: 10.1194/jlr.O072629  0.4
2017 Link JC, Hasin-Brumshtein Y, Cantor RM, Chen X, Arnold AP, Lusis AJ, Reue K. Diet, gonadal sex, and sex chromosome complement influence white adipose tissue miRNA expression. Bmc Genomics. 18: 89. PMID 28095800 DOI: 10.1186/s12864-017-3484-1  0.4
2017 Rau CD, Civelek M, Pan C, Lusis AJ. A Suite of Tools for Biologists That Improve Accessibility and Visualization of Large Systems Genetics Datasets: Applications to the Hybrid Mouse Diversity Panel. Methods in Molecular Biology (Clifton, N.J.). 1488: 153-188. PMID 27933524 DOI: 10.1007/978-1-4939-6427-7_7  0.48
2016 von Scheidt M, Zhao Y, Kurt Z, Pan C, Zeng L, Yang X, Schunkert H, Lusis AJ. Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis. Cell Metabolism. PMID 27916529 DOI: 10.1016/j.cmet.2016.11.001  0.84
2016 Pillai IC, Li S, Romay M, Lam L, Lu Y, Huang J, Dillard N, Zemanova M, Rubbi L, Wang Y, Lee J, Xia M, Liang O, Xie YH, Pellegrini M, ... Lusis AJ, et al. Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. Cell Stem Cell. PMID 27867037 DOI: 10.1016/j.stem.2016.10.005  0.68
2016 Rau CD, Romay MC, Tuteryan M, Wang JJ, Santolini M, Ren S, Karma A, Weiss JN, Wang Y, Lusis AJ. Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell Systems. PMID 27866946 DOI: 10.1016/j.cels.2016.10.016  0.48
2016 Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Mäkinen VP, Yang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. Bmc Genomics. 17: 874. PMID 27814671 DOI: 10.1186/s12864-016-3198-9  0.84
2016 Norheim F, Hui ST, Kulahcioglu E, Mehrabian M, Cantor RM, Pan C, Parks BW, Lusis AJ. Genetic and hormonal control of hepatic steatosis in female and male mice. Journal of Lipid Research. PMID 27811231 DOI: 10.1194/jlr.M071522  0.56
2016 Joo JW, Kang EY, Org E, Furlotte N, Parks B, Hormozdiari F, Lusis AJ, Eskin E. Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure. Genetics. PMID 27770036 DOI: 10.1534/genetics.116.189712  0.52
2016 Kang EY, Martin L, Mangul S, Isvilanonda W, Zou J, Ben-David E, Han B, Lusis AJ, Shifman S, Eskin E. Discovering SNPs Regulating Human Gene Expression Using Allele Specific Expression from RNA-Seq Data. Genetics. PMID 27765809 DOI: 10.1534/genetics.115.177246  0.36
2016 Touat-Hamici Z, Weidmann H, Blum Y, Proust C, Durand H, Iannacci F, Codoni V, Gaignard P, Thérond P, Civelek M, Karabina AS, Lusis AJ, Cambien F, Ninio E. Role of lipid phosphate phosphatase 3 (LPP3) in human aortic endothelial cell function. Cardiovascular Research. PMID 27694435 DOI: 10.1093/cvr/cvw217  0.48
2016 Wågsäter D, Vorkapic E, van Stijn CM, Kim J, Lusis AJ, Eriksson P, Tangirala RK. Elevated Adiponectin Levels Suppress Perivascular and Aortic Inflammation and Prevent AngII-induced Advanced Abdominal Aortic Aneurysms. Scientific Reports. 6: 31414. PMID 27659201 DOI: 10.1038/srep31414  0.32
2016 Hasin-Brumshtein Y, Khan AH, Hormozdiari F, Pan C, Parks BW, Petyuk VA, Piehowski PD, Bruemmer A, Pellegrini M, Xiao X, Eskin E, Smith RD, Lusis AJ, Smith DJ. Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes. Elife. 5. PMID 27623010 DOI: 10.7554/eLife.15614  0.68
2016 Codoni V, Blum Y, Civelek M, Proust C, Franzén O, Björkegren JL, Le Goff W, Cambien F, Lusis AJ, Trégouët DA. Preservation Analysis of Macrophage Gene Co-expression Between Human and Mouse Identifies PARK2 as a Genetically controlled Master Regulator of Oxydative Phosphorylation in Humans. G3 (Bethesda, Md.). PMID 27558669 DOI: 10.1534/g3.116.033894  0.48
2016 Salehi P, Myint A, Kim YJ, Ge MX, Lavinsky J, Ho MK, Crow AL, Cruz C, Monges-Hernadez M, Wang J, Hartiala J, Zhang LI, Allayee H, Lusis AJ, Ohyama T, et al. Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice. Journal of the Association For Research in Otolaryngology : Jaro. PMID 27539716 DOI: 10.1007/s10162-016-0578-4  0.48
2016 Lavinsky J, Ge M, Crow AL, Pan C, Wang J, Dermanaki PS, Myint A, Eskin E, Allayee H, Lusis AJ, Friedman RA. The Genetic Architecture of Noise-induced Hearing Loss: Evidence for a Gene-by-Environment Interaction. G3 (Bethesda, Md.). PMID 27520957 DOI: 10.1534/g3.116.032516  0.48
2016 Wang JJ, Rau C, Avetisyan R, Ren S, Romay MC, Stolin G, Gong KW, Wang Y, Lusis AJ. Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. Plos Genetics. 12: e1006038. PMID 27385019 DOI: 10.1371/journal.pgen.1006038  0.84
2016 Org E, Mehrabian M, Parks BW, Shipkova P, Liu X, Drake TA, Lusis AJ. Sex differences and hormonal effects on gut microbiota composition in mice. Gut Microbes. 0. PMID 27355107 DOI: 10.1080/19490976.2016.1203502  0.84
2016 Hormozdiari F, Kang EY, Bilow M, Ben-David E, Vulpe C, McLachlan S, Lusis AJ, Han B, Eskin E. Imputing Phenotypes for Genome-wide Association Studies. American Journal of Human Genetics. PMID 27292110 DOI: 10.1016/j.ajhg.2016.04.013  0.36
2016 Karbassi E, Monte E, Chapski DJ, Lopez R, Rosa Garrido M, Kim J, Wisniewski NN, Rau CC, Wang JJ, Weiss JN, Wang Y, Lusis AJ, Vondriska TM. Relationship of Disease-Associated Gene Expression to Cardiac Phenotype is Buffered by Genetic Diversity and Chromatin Regulation. Physiological Genomics. physiolgenomics.0003. PMID 27287924 DOI: 10.1152/physiolgenomics.00035.2016  0.48
2016 Monte E, Rosa-Garrido M, Karbassi E, Chen H, Lopez R, Rau CD, Wang J, Nelson SF, Wu Y, Stefani E, Lusis AJ, Wang Y, Kurdistani SK, Franklin S, Vondriska TM. Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins HMGB and CTCF: Implications for Transcriptional Regulation. The Journal of Biological Chemistry. PMID 27226577 DOI: 10.1074/jbc.M116.719633  0.48
2016 Talukdar HA, Foroughi Asl H, Jain RK, Ermel R, Ruusalepp A, Franzén O, Kidd BA, Readhead B, Giannarelli C, Kovacic JC, Ivert T, Dudley JT, Civelek M, Lusis AJ, Schadt EE, et al. Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease. Cell Systems. 2: 196-208. PMID 27135365 DOI: 10.1016/j.cels.2016.02.002  0.56
2016 Lusis AJ, Seldin M, Allayee H, Bennett BJ, Civelek M, Davis RC, Eskin E, Farber C, Hui ST, Mehrabian M, Norheim F, Pan C, Parks B, Rau C, Smith DJ, et al. The Hybrid Mouse Diversity Panel: A Resource for Systems Genetics Analyses of Metabolic and Cardiovascular Traits. Journal of Lipid Research. PMID 27099397 DOI: 10.1194/jlr.R066944  0.84
2016 Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, ... ... Lusis AJ, et al. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science Translational Medicine. 8: 334ra54. PMID 27075628 DOI: 10.1126/scitranslmed.aad3815  0.48
2016 Zhu W, Gregory JC, Org E, Buffa JA, Gupta N, Wang Z, Li L, Fu X, Wu Y, Mehrabian M, Sartor RB, McIntyre TM, Silverstein RL, Tang WH, DiDonato JA, ... ... Lusis AJ, et al. Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk. Cell. PMID 26972052 DOI: 10.1016/j.cell.2016.02.011  0.56
2016 Chattopadhyay A, Navab M, Hough G, Grijalva V, Mukherjee P, Fogelman HR, Hwang LH, Faull KF, Lusis AJ, Reddy ST, Fogelman AM. Tomatoes expressing the 6F Peptide Ameliorate the Increase in Oxidized Phospholipids in the Jejunum of Mice Fed Unsaturated Lysophosphatidylcholine or Western Diet. Journal of Lipid Research. PMID 26965826 DOI: 10.1194/jlr.M064352  0.56
2016 Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Sevag Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, ... ... Lusis AJ, et al. Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. Plos Genetics. 12: e1005913. PMID 26934746 DOI: 10.1371/journal.pgen.1005913  0.8
2016 Seldin MM, Meng Y, Qi H, Zhu W, Wang Z, Hazen SL, Lusis AJ, Shih DM. Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB. Journal of the American Heart Association. 5. PMID 26903003 DOI: 10.1161/JAHA.115.002767  0.64
2016 Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx BW, Jansen R, de Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E, Alvarez M, Civelek M, Lusis AJ, et al. Integrative approaches for large-scale transcriptome-wide association studies. Nature Genetics. PMID 26854917 DOI: 10.1038/ng.3506  0.48
2016 Chen H, Orozco LD, Wang J, Rau CD, Rubbi L, Ren S, Wang Y, Pellegrini M, Lusis AJ, Vondriska TM. DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. Circulation Research. PMID 26838786 DOI: 10.1161/CIRCRESAHA.115.305298  0.68
2015 Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, ... ... Lusis AJ, et al. Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. Plos Genetics. 11: e1005711. PMID 26694027 DOI: 10.1371/journal.pgen.1005711  0.84
2015 Wang Z, Roberts AB, Buffa JA, Levison BS, Zhu W, Org E, Gu X, Huang Y, Zamanian-Daryoush M, Culley MK, DiDonato AJ, Fu X, Hazen JE, Krajcik D, DiDonato JA, ... Lusis AJ, et al. Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis. Cell. 163: 1585-95. PMID 26687352 DOI: 10.1016/j.cell.2015.11.055  0.44
2015 Roman TS, Marvelle AF, Fogarty MP, Vadlamudi S, Gonzalez AJ, Buchkovich ML, Huyghe JR, Fuchsberger C, Jackson AU, Wu Y, Civelek M, Lusis AJ, Gaulton KJ, Sethupathy P, Kangas AJ, et al. Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol. American Journal of Human Genetics. 97: 801-15. PMID 26637976 DOI: 10.1016/j.ajhg.2015.10.016  0.48
2015 Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, et al. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of Experimental Medicine. PMID 26552708 DOI: 10.1084/jem.20150603  0.56
2015 Crow AL, Ohmen J, Wang J, Lavinsky J, Hartiala J, Li Q, Li X, Salehide P, Eskin E, Pan C, Lusis AJ, Allayee H, Friedman RA. The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency Specific Genetic Determinants. G3 (Bethesda, Md.). PMID 26342000 DOI: 10.1534/g3.115.021592  0.48
2015 Brænne I, Civelek M, Vilne B, Di Narzo A, Johnson AD, Zhao Y, Reiz B, Codoni V, Webb TR, Foroughi Asl H, Hamby SE, Zeng L, Trégouët DA, Hao K, Topol EJ, ... ... Lusis AJ, et al. Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26293461 DOI: 10.1161/ATVBAHA.115.306108  0.84
2015 Org E, Parks BW, Joo JW, Emert B, Schwartzman W, Kang EY, Mehrabian M, Pan C, Knight R, Gunsalus R, Drake TA, Eskin E, Lusis AJ. Genetic and environmental control of host-gut microbiota interactions. Genome Research. PMID 26260972 DOI: 10.1101/gr.194118.115  0.84
2015 Rau CD, Parks B, Wang Y, Eskin E, Simecek P, Churchill GA, Lusis AJ. High Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda, Md.). PMID 26224782 DOI: 10.1534/g3.115.020784  0.84
2015 Lusis AJ. Cardiovascular disease genes come together. Atherosclerosis. 242: 630-1. PMID 26152393 DOI: 10.1016/j.atherosclerosis.2015.06.024  0.84
2015 Nanda V, Gutman B, Bar E, Alghamdi S, Tetradis S, Lusis AJ, Eskin E, Moon W. Quantitative analysis of 3-dimensional facial soft tissue photographic images: technical methods and clinical application. Progress in Orthodontics. 16: 21. PMID 26133934 DOI: 10.1186/s40510-015-0082-0  0.84
2015 Org E, Mehrabian M, Lusis AJ. Unraveling the environmental and genetic interactions in atherosclerosis: Central role of the gut microbiota. Atherosclerosis. 241: 387-99. PMID 26071662 DOI: 10.1016/j.atherosclerosis.2015.05.035  0.84
2015 Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss. Plos Genetics. 11: e1005293. PMID 26068505 DOI: 10.1371/journal.pgen.1005293  0.48
2015 Hui ST, Parks BW, Org E, Norheim F, Che N, Pan C, Castellani LW, Charugundla S, Dirks DL, Psychogios N, Neuhaus I, Gerszten RE, Kirchgessner T, Gargalovic PS, Lusis AJ. The genetic architecture of NAFLD among inbred strains of mice. Elife. 4. PMID 26067236 DOI: 10.7554/eLife.05607  0.84
2015 Zhou X, Crow AL, Hartiala J, Spindler TJ, Ghazalpour A, Barsky LW, Bennett BB, Parks BW, Eskin E, Jain R, Epstein JA, Lusis AJ, Adams GB, Allayee H. The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. Stem Cell Reports. PMID 26050929 DOI: 10.1016/j.stemcr.2015.05.008  0.84
2015 Orozco LD, Morselli M, Rubbi L, Guo W, Go J, Shi H, Lopez D, Furlotte NA, Bennett BJ, Farber CR, Ghazalpour A, Zhang MQ, Bahous R, Rozen R, Lusis AJ, et al. Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice. Cell Metabolism. 21: 905-17. PMID 26039453 DOI: 10.1016/j.cmet.2015.04.025  0.84
2015 Wu C, Huang RT, Kuo CH, Kumar S, Kim CW, Lin YC, Chen YJ, Birukova A, Birukov KG, Dulin N, Civelek M, Lusis AJ, Loyer X, Tedgui A, Dai G, et al. Mechano-Sensitive PPAP2B Regulates Endothelial Responses to Athero-Relevant Hemodynamic Forces. Circulation Research. PMID 26034042 DOI: 10.1161/CIRCRESAHA.117.306457  0.48
2015 Kenagy RD, Civelek M, Kikuchi S, Chen L, Grieff A, Sobel M, Lusis AJ, Clowes AW. Scavenger receptor class A member 5 (SCARA5) and suprabasin (SBSN) are hub genes of coexpression network modules associated with peripheral vein graft patency. Journal of Vascular Surgery. PMID 25935274 DOI: 10.1016/j.jvs.2014.12.052  0.84
2015 Blazquez-Medela AM, Guihard PJ, Yao J, Jumabay M, Lusis AJ, Boström KI, Yao Y. ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney. Febs Open Bio. 5: 257-63. PMID 25893161 DOI: 10.1016/j.fob.2015.03.009  0.32
2015 Fox CS, Hall JL, Arnett DK, Ashley EA, Delles C, Engler MB, Freeman MW, Johnson JA, Lanfear DE, Liggett SB, Lusis AJ, Loscalzo J, MacRae CA, Musunuru K, Newby LK, et al. Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation. 131: 1715-36. PMID 25882488 DOI: 10.1161/CIR.0000000000000211  0.84
2015 Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss. Plos Genetics. 11: e1005094. PMID 25880434 DOI: 10.1371/journal.pgen.1005094  0.84
2015 Rau CD, Lusis AJ, Wang Y. Genetics of common forms of heart failure: challenges and potential solutions. Current Opinion in Cardiology. 30: 222-7. PMID 25768955 DOI: 10.1097/HCO.0000000000000160  0.84
2015 Roux PF, Boitard S, Blum Y, Parks B, Montagner A, Mouisel E, Djari A, Esquerré D, Désert C, Boutin M, Leroux S, Lecerf F, Le Bihan-Duval E, Klopp C, Servin B, ... ... Lusis AJ, et al. Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation. G3 (Bethesda, Md.). 5: 517-29. PMID 25653314 DOI: 10.1534/g3.115.016865  0.84
2015 Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, ... ... Lusis AJ, et al. Genetic architecture of insulin resistance in the mouse. Cell Metabolism. 21: 334-46. PMID 25651185 DOI: 10.1016/j.cmet.2015.01.002  0.84
2015 Gregory JC, Buffa JA, Org E, Wang Z, Levison BS, Zhu W, Wagner MA, Bennett BJ, Li L, DiDonato JA, Lusis AJ, Hazen SL. Transmission of atherosclerosis susceptibility with gut microbial transplantation. The Journal of Biological Chemistry. 290: 5647-60. PMID 25550161 DOI: 10.1074/jbc.M114.618249  0.84
2015 Rau CD, Wang J, Avetisyan R, Romay MC, Martin L, Ren S, Wang Y, Lusis AJ. Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice. Circulation. Cardiovascular Genetics. 8: 40-9. PMID 25480693 DOI: 10.1161/CIRCGENETICS.113.000732  0.84
2015 Shih DM, Yu JM, Vergnes L, Dali-Youcef N, Champion MD, Devarajan A, Zhang P, Castellani LW, Brindley DN, Jamey C, Auwerx J, Reddy ST, Ford DA, Reue K, Lusis AJ. PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1185-97. PMID 25477283 DOI: 10.1096/fj.14-260570  0.84
2015 Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, ... Lusis AJ, et al. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of Biological Chemistry. 290: 5566-81. PMID 25468909 DOI: 10.1074/jbc.M114.606459  0.84
2015 van Stijn CM, Kim J, Lusis AJ, Barish GD, Tangirala RK. Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti-inflammatory response. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 636-49. PMID 25392268 DOI: 10.1096/fj.14-253831  0.84
2015 Shih DM, Wang Z, Lee R, Meng Y, Che N, Charugundla S, Qi H, Wu J, Pan C, Brown JM, Vallim T, Bennett BJ, Graham M, Hazen SL, Lusis AJ. Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis. Journal of Lipid Research. 56: 22-37. PMID 25378658 DOI: 10.1194/jlr.M051680  0.84
2015 Romay MC, Che N, Becker SN, Pouldar D, Hagopian R, Xiao X, Lusis AJ, Berliner JA, Civelek M. Regulation of NF-κB signaling by oxidized glycerophospholipid and IL-1β induced miRs-21-3p and -27a-5p in human aortic endothelial cells. Journal of Lipid Research. 56: 38-50. PMID 25327529 DOI: 10.1194/jlr.M052670  0.68
2014 Gordts PL, Foley EM, Lawrence R, Sinha R, Lameda-Diaz C, Deng L, Nock R, Glass CK, Erbilgin A, Lusis AJ, Witztum JL, Esko JD. Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling. Cell Metabolism. 20: 813-26. PMID 25440058 DOI: 10.1016/j.cmet.2014.09.016  0.84
2014 Koeth RA, Levison BS, Culley MK, Buffa JA, Wang Z, Gregory JC, Org E, Wu Y, Li L, Smith JD, Tang WH, DiDonato JA, Lusis AJ, Hazen SL. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metabolism. 20: 799-812. PMID 25440057 DOI: 10.1016/j.cmet.2014.10.006  0.84
2014 Wu X, Davis RC, McMillen TS, Schaeffer V, Zhou Z, Qi H, Mazandarani PN, Alialy R, Hudkins KL, Lusis AJ, LeBoeuf RC. Genetic modulation of diabetic nephropathy among mouse strains with Ins2 Akita mutation. Physiological Reports. 2. PMID 25428948 DOI: 10.14814/phy2.12208  0.8
2014 Chan KH, Huang YT, Meng Q, Wu C, Reiner A, Sobel EM, Tinker L, Lusis AJ, Yang X, Liu S. Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities. Circulation. Cardiovascular Genetics. 7: 911-9. PMID 25371518 DOI: 10.1161/CIRCGENETICS.114.000676  0.84
2014 Civelek M, Lusis AJ. From hairballs to an understanding of transendothelial migration of monocytes in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1809-10. PMID 25142882 DOI: 10.1161/ATVBAHA.114.304151  0.84
2014 Albright J, Quizon PM, Lusis AJ, Bennett BJ. Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery. Bmc Medical Genomics. 7: 51. PMID 25115202 DOI: 10.1186/1755-8794-7-51  0.84
2014 Bolnick DI, Snowberg LK, Hirsch PE, Lauber CL, Org E, Parks B, Lusis AJ, Knight R, Caporaso JG, Svanbäck R. Individual diet has sex-dependent effects on vertebrate gut microbiota. Nature Communications. 5: 4500. PMID 25072318 DOI: 10.1038/ncomms5500  0.84
2014 Mäkinen VP, Civelek M, Meng Q, Zhang B, Zhu J, Levian C, Huan T, Segrè AV, Ghosh S, Vivar J, Nikpay M, Stewart AF, Nelson CP, Willenborg C, Erdmann J, ... ... Lusis AJ, et al. Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. Plos Genetics. 10: e1004502. PMID 25033284 DOI: 10.1371/journal.pgen.1004502  0.84
2014 Leung A, Parks BW, Du J, Trac C, Setten R, Chen Y, Brown K, Lusis AJ, Natarajan R, Schones DE. Open chromatin profiling in mice livers reveals unique chromatin variations induced by high fat diet. The Journal of Biological Chemistry. 289: 23557-67. PMID 25006255 DOI: 10.1074/jbc.M114.581439  0.84
2014 Calkin AC, Lee SD, Kim J, Van Stijn CM, Wu XH, Lusis AJ, Hong C, Tangirala RI, Tontonoz P. Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice. Circulation Research. 115: 442-9. PMID 24935961 DOI: 10.1161/CIRCRESAHA.115.304440  0.48
2014 Hasin-Brumshtein Y, Hormozdiari F, Martin L, van Nas A, Eskin E, Lusis AJ, Drake TA. Allele-specific expression and eQTL analysis in mouse adipose tissue. Bmc Genomics. 15: 471. PMID 24927774 DOI: 10.1186/1471-2164-15-471  0.84
2014 Orozco LD, Rubbi L, Martin LJ, Fang F, Hormozdiari F, Che N, Smith AD, Lusis AJ, Pellegrini M. Intergenerational genomic DNA methylation patterns in mouse hybrid strains. Genome Biology. 15: R68. PMID 24887417 DOI: 10.1186/gb-2014-15-5-r68  0.68
2014 Ghazalpour A, Bennett BJ, Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang WP, Kirchgessner T, Lusis AJ. Genetic regulation of mouse liver metabolite levels. Molecular Systems Biology. 10: 730. PMID 24860088 DOI: 10.15252/msb.20135004  0.84
2014 Emert B, Hasin-Brumshtein Y, Springstead JR, Vakili L, Berliner JA, Lusis AJ. HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms. Journal of Lipid Research. 55: 1678-1692. PMID 24859737 DOI: 10.1194/jlr.M047738  0.84
2014 Hartiala J, Bennett BJ, Tang WH, Wang Z, Stewart AF, Roberts R, McPherson R, Lusis AJ, Hazen SL, Allayee H. Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1307-13. PMID 24675659 DOI: 10.1161/ATVBAHA.114.303252  0.84
2014 Csaki LS, Dwyer JR, Li X, Nguyen MH, Dewald J, Brindley DN, Lusis AJ, Yoshinaga Y, de Jong P, Fong L, Young SG, Reue K. Lipin-1 and lipin-3 together determine adiposity in vivo. Molecular Metabolism. 3: 145-54. PMID 24634820 DOI: 10.1016/j.molmet.2013.11.008  0.84
2014 Ohmen J, Kang EY, Li X, Joo JW, Hormozdiari F, Zheng QY, Davis RC, Lusis AJ, Eskin E, Friedman RA. Genome-wide association study for age-related hearing loss (AHL) in the mouse: a meta-analysis. Journal of the Association For Research in Otolaryngology : Jaro. 15: 335-52. PMID 24570207 DOI: 10.1007/s10162-014-0443-2  0.84
2014 Okamoto R, Gery S, Gombart AF, Wang X, Castellani LW, Akagi T, Chen S, Arditi M, Ho Q, Lusis AJ, Li Q, Koeffler HP. Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- Mice Plos One. 9. PMID 24489659 DOI: 10.1371/journal.pone.0085341  0.84
2014 Kang EY, Han B, Furlotte N, Joo JW, Shih D, Davis RC, Lusis AJ, Eskin E. Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice. Plos Genetics. 10: e1004022. PMID 24415945 DOI: 10.1371/journal.pgen.1004022  0.84
2014 Civelek M, Lusis AJ. Systems genetics approaches to understand complex traits. Nature Reviews. Genetics. 15: 34-48. PMID 24296534 DOI: 10.1038/nrg3575  0.84
2013 Maubaret CG, Salpea KD, Romanoski CE, Folkersen L, Cooper JA, Stephanou C, Li KW, Palmen J, Hamsten A, Neil A, Stephens JW, Lusis AJ, Eriksson P, Talmud PJ, Humphries SE, et al. Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease. Plos One. 8: e83122. PMID 24349443 DOI: 10.1371/journal.pone.0083122  0.84
2013 Parks BW, Lusis AJ. Macrophage accumulation in atherosclerosis. The New England Journal of Medicine. 369: 2352-3. PMID 24328470 DOI: 10.1056/NEJMcibr1312709  0.84
2013 Lu G, Ota A, Ren S, Franklin S, Rau CD, Ping P, Lane TF, Zhou ZH, Reue K, Lusis AJ, Vondriska T, Wang Y. PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Molecular Metabolism. 2: 405-16. PMID 24327956 DOI: 10.1016/j.molmet.2013.07.005  0.84
2013 Kautz L, Gabayan V, Wang X, Wu J, Onwuzurike J, Jung G, Qiao B, Lusis AJ, Ganz T, Nemeth E. Testing the iron hypothesis in a mouse model of atherosclerosis. Cell Reports. 5: 1436-42. PMID 24316081 DOI: 10.1016/j.celrep.2013.11.009  0.44
2013 Welch C, Lusis AJ. Genetics of common forms of heart disease: a long and winding road. Circulation Research. 113: 1035-6. PMID 24115066 DOI: 10.1161/CIRCRESAHA.113.302425  0.84
2013 Navab M, Hough G, Buga GM, Su F, Wagner AC, Meriwether D, Chattopadhyay A, Gao F, Grijalva V, Danciger JS, Van Lenten BJ, Org E, Lusis AJ, Pan C, Anantharamaiah GM, et al. Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid. Journal of Lipid Research. 54: 3403-18. PMID 24085744 DOI: 10.1194/jlr.M042051  0.56
2013 Lagarrigue S, Martin L, Hormozdiari F, Roux PF, Pan C, van Nas A, Demeure O, Cantor R, Ghazalpour A, Eskin E, Lusis AJ. Analysis of allele-specific expression in mouse liver by RNA-Seq: a comparison with Cis-eQTL identified using genetic linkage. Genetics. 195: 1157-66. PMID 24026101 DOI: 10.1534/genetics.113.153882  0.84
2013 Erbilgin A, Siemers N, Kayne P, Yang WP, Berliner J, Lusis AJ. Gene expression analyses of mouse aortic endothelium in response to atherogenic stimuli. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2509-17. PMID 23990205 DOI: 10.1161/ATVBAHA.113.301989  0.84
2013 Huang Y, Wu Z, Riwanto M, Gao S, Levison BS, Gu X, Fu X, Wagner MA, Besler C, Gerstenecker G, Zhang R, Li XM, DiDonato AJ, Gogonea V, Tang WH, ... ... Lusis AJ, et al. Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. The Journal of Clinical Investigation. 123: 3815-28. PMID 23908111 DOI: 10.1172/JCI67478  0.84
2013 Shih DM, Shaposhnik Z, Meng Y, Rosales M, Wang X, Wu J, Ratiner B, Zadini F, Zadini G, Lusis AJ. Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3805-17. PMID 23752203 DOI: 10.1096/fj.12-223008  0.84
2013 van Nas A, Pan C, Ingram-Drake LA, Ghazalpour A, Drake TA, Sobel EM, Papp JC, Lusis AJ. The systems genetics resource: a web application to mine global data for complex disease traits. Frontiers in Genetics. 4: 84. PMID 23730305 DOI: 10.3389/fgene.2013.00084  0.84
2013 Erbilgin A, Civelek M, Romanoski CE, Pan C, Hagopian R, Berliner JA, Lusis AJ. Identification of CAD candidate genes in GWAS loci and their expression in vascular cells. Journal of Lipid Research. 54: 1894-905. PMID 23667179 DOI: 10.1194/jlr.M037085  0.84
2013 Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, ... Lusis AJ, et al. Response to Pomozi et al's research commentary. Circulation Research. 112: e152-3. PMID 23625949 DOI: 10.1161/CIRCRESAHA.113.301666  0.84
2013 Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, ... ... Lusis AJ, et al. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nature Medicine. 19: 576-85. PMID 23563705 DOI: 10.1038/nm.3145  0.84
2013 Civelek M, Hagopian R, Pan C, Che N, Yang WP, Kayne PS, Saleem NK, Cederberg H, Kuusisto J, Gargalovic PS, Kirchgessner TG, Laakso M, Lusis AJ. Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits. Human Molecular Genetics. 22: 3023-37. PMID 23562819 DOI: 10.1093/hmg/ddt159  0.84
2013 Mahendran Y, Vangipurapu J, Cederberg H, Stancáková A, Pihlajamäki J, Soininen P, Kangas AJ, Paananen J, Civelek M, Saleem NK, Pajukanta P, Lusis AJ, Bonnycastle LL, Morken MA, Collins FS, et al. Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men. Diabetes. 62: 3618-26. PMID 23557707 DOI: 10.2337/db12-1363  0.84
2013 Weissglas-Volkov D, Aguilar-Salinas CA, Nikkola E, Deere KA, Cruz-Bautista I, Arellano-Campos O, Muñoz-Hernandez LL, Gomez-Munguia L, Ordoñez-Sánchez ML, Reddy PM, Lusis AJ, Matikainen N, Taskinen MR, Riba L, Cantor RM, et al. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. Journal of Medical Genetics. 50: 298-308. PMID 23505323 DOI: 10.1136/jmedgenet-2012-101461  0.84
2013 Rau CD, Wisniewski N, Orozco LD, Bennett B, Weiss J, Lusis AJ. Maximal information component analysis: a novel non-linear network analysis method. Frontiers in Genetics. 4: 28. PMID 23487572 DOI: 10.3389/fgene.2013.00028  0.84
2013 Davis RC, van Nas A, Bennett B, Orozco L, Pan C, Rau CD, Eskin E, Lusis AJ. Genome-wide association mapping of blood cell traits in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 105-18. PMID 23417284 DOI: 10.1007/s00335-013-9448-0  0.84
2013 Lagarrigue S, Hormozdiari F, Martin LJ, Lecerf F, Hasin Y, Rau C, Hagopian R, Xiao Y, Yan J, Drake TA, Ghazalpour A, Eskin E, Lusis AJ. Limited RNA editing in exons of mouse liver and adipose. Genetics. 193: 1107-15. PMID 23410828 DOI: 10.1534/genetics.112.149054  0.84
2013 Parks BW, Nam E, Org E, Kostem E, Norheim F, Hui ST, Pan C, Civelek M, Rau CD, Bennett BJ, Mehrabian M, Ursell LK, He A, Castellani LW, Zinker B, ... ... Lusis AJ, et al. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metabolism. 17: 141-52. PMID 23312289 DOI: 10.1016/j.cmet.2012.12.007  0.84
2013 Bennett BJ, de Aguiar Vallim TQ, Wang Z, Shih DM, Meng Y, Gregory J, Allayee H, Lee R, Graham M, Crooke R, Edwards PA, Hazen SL, Lusis AJ. Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metabolism. 17: 49-60. PMID 23312283 DOI: 10.1016/j.cmet.2012.12.011  0.84
2013 Marquart TJ, Wu J, Lusis AJ, Baldán Á. Anti-miR-33 therapy does not alter the progression of atherosclerosis in low-density lipoprotein receptor-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 455-8. PMID 23288159 DOI: 10.1161/ATVBAHA.112.300639  0.84
2013 Halperin DS, Pan C, Lusis AJ, Tontonoz P. Vestigial-like 3 is an inhibitor of adipocyte differentiation. Journal of Lipid Research. 54: 473-81. PMID 23152581 DOI: 10.1194/jlr.M032755  0.84
2012 Calabrese G, Bennett BJ, Orozco L, Kang HM, Eskin E, Dombret C, De Backer O, Lusis AJ, Farber CR. Systems genetic analysis of osteoblast-lineage cells. Plos Genetics. 8: e1003150. PMID 23300464 DOI: 10.1371/journal.pgen.1003150  0.84
2012 Orozco LD, Bennett BJ, Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, Neuhaus I, Yordanova R, Gargalovic P, Pellegrini M, Kirchgessner T, ... Lusis AJ, et al. Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages. Cell. 151: 658-70. PMID 23101632 DOI: 10.1016/j.cell.2012.08.043  0.84
2012 Kim JB, Deluna A, Mungrue IN, Vu C, Pouldar D, Civelek M, Orozco L, Wu J, Wang X, Charugundla S, Castellani LW, Rusek M, Jakubowski H, Jakobowski H, Lusis AJ. Effect of 9p21.3 coronary artery disease locus neighboring genes on atherosclerosis in mice. Circulation. 126: 1896-906. PMID 22952318 DOI: 10.1161/CIRCULATIONAHA.111.064881  0.84
2012 Lee S, Birukov KG, Romanoski CE, Springstead JR, Lusis AJ, Berliner JA. Role of phospholipid oxidation products in atherosclerosis. Circulation Research. 111: 778-99. PMID 22935534 DOI: 10.1161/CIRCRESAHA.111.256859  0.84
2012 Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, ... ... Lusis AJ, et al. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 680-92. PMID 22892838 DOI: 10.1007/s00335-012-9411-5  0.84
2012 Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. "Good enough solutions" and the genetics of complex diseases. Circulation Research. 111: 493-504. PMID 22859671 DOI: 10.1161/CIRCRESAHA.112.269084  0.84
2012 Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, ... Lusis AJ, et al. ABCC6 localizes to the mitochondria-associated membrane. Circulation Research. 111: 516-20. PMID 22811557 DOI: 10.1161/CIRCRESAHA.112.276667  0.84
2012 Bennett BJ, Orozco L, Kostem E, Erbilgin A, Dallinga M, Neuhaus I, Guan B, Wang X, Eskin E, Lusis AJ. High-resolution association mapping of atherosclerosis loci in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1790-8. PMID 22723443 DOI: 10.1161/ATVBAHA.112.253864  0.84
2012 Smolock EM, Ilyushkina IA, Ghazalpour A, Gerloff J, Murashev AN, Lusis AJ, Korshunov VA. Genetic locus on mouse chromosome 7 controls elevated heart rate. Physiological Genomics. 44: 689-98. PMID 22589454 DOI: 10.1152/physiolgenomics.00041.2012  0.84
2012 Stancáková A, Civelek M, Saleem NK, Soininen P, Kangas AJ, Cederberg H, Paananen J, Pihlajamäki J, Bonnycastle LL, Morken MA, Boehnke M, Pajukanta P, Lusis AJ, Collins FS, Kuusisto J, et al. Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men. Diabetes. 61: 1895-902. PMID 22553379 DOI: 10.2337/db11-1378  0.84
2012 Ishikawa K, Navab M, Lusis AJ. Vasculitis, Atherosclerosis, and Altered HDL Composition in Heme-Oxygenase-1-Knockout Mice. International Journal of Hypertension. 2012: 948203. PMID 22518297 DOI: 10.1155/2012/948203  0.84
2012 Furlotte NA, Kang EY, Van Nas A, Farber CR, Lusis AJ, Eskin E. Increasing association mapping power and resolution in mouse genetic studies through the use of meta-analysis for structured populations. Genetics. 191: 959-67. PMID 22505625 DOI: 10.1534/genetics.112.140277  0.84
2012 Lusis AJ. Genetics of atherosclerosis. Trends in Genetics : Tig. 28: 267-75. PMID 22480919 DOI: 10.1016/j.tig.2012.03.001  0.84
2012 Hong C, Bradley MN, Rong X, Wang X, Wagner A, Grijalva V, Castellani LW, Salazar J, Realegeno S, Boyadjian R, Fogelman AM, Van Lenten BJ, Reddy ST, Lusis AJ, Tangirala RK, et al. LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice Journal of Lipid Research. 53: 1126-1133. PMID 22454476 DOI: 10.1194/jlr.M022061  0.84
2012 Arnold AP, Lusis AJ. Understanding the sexome: measuring and reporting sex differences in gene systems. Endocrinology. 153: 2551-5. PMID 22434084 DOI: 10.1210/en.2011-2134  0.84
2012 Lee S, Springstead JR, Parks BW, Romanoski CE, Palvolgyi R, Ho T, Nguyen P, Lusis AJ, Berliner JA. Metalloproteinase processing of HBEGF is a proximal event in the response of human aortic endothelial cells to oxidized phospholipids. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1246-54. PMID 22402363 DOI: 10.1161/ATVBAHA.111.241257  0.84
2012 Lusis AJ. Life after GWAS: functional genomics in vascular biology. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 169. PMID 22258899 DOI: 10.1161/ATVBAHA.111.243543  0.84
2012 MacLellan WR, Wang Y, Lusis AJ. Systems-based approaches to cardiovascular disease. Nature Reviews. Cardiology. 9: 172-84. PMID 22231714 DOI: 10.1038/nrcardio.2011.208  0.84
2012 Johansen CT, Wang J, McIntyre AD, Martins RA, Ban MR, Lanktree MB, Huff MW, Péterfy M, Mehrabian M, Lusis AJ, Kathiresan S, Anand SS, Yusuf S, Lee AH, Glimcher LH, et al. Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia. Circulation. Cardiovascular Genetics. 5: 66-72. PMID 22135386 DOI: 10.1161/CIRCGENETICS.111.960864  0.56
2012 Davis RC, van Nas A, Castellani LW, Zhao Y, Zhou Z, Wen P, Yu S, Qi H, Rosales M, Schadt EE, Broman KW, Péterfy M, Lusis AJ. Systems genetics of susceptibility to obesity-induced diabetes in mice. Physiological Genomics. 44: 1-13. PMID 22010005 DOI: 10.1152/physiolgenomics.00003.2011  0.84
2012 Langfelder P, Castellani LW, Zhou Z, Paul E, Davis R, Schadt EE, Lusis AJ, Horvath S, Mehrabian M. A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. Biochimica Et Biophysica Acta. 1821: 435-47. PMID 21807117 DOI: 10.1016/j.bbalip.2011.07.014  0.84
2011 Terra JK, France B, Cote CK, Jenkins A, Bozue JA, Welkos SL, Bhargava R, Ho CL, Mehrabian M, Pan C, Lusis AJ, Davis RC, LeVine SM, Bradley KA. Allelic variation on murine chromosome 11 modifies host inflammatory responses and resistance to Bacillus anthracis. Plos Pathogens. 7: e1002469. PMID 22241984 DOI: 10.1371/journal.ppat.1002469  0.84
2011 Mungrue IN, Zhao P, Yao Y, Meng H, Rau C, Havel JV, Gorgels TG, Bergen AA, MacLellan WR, Drake TA, Boström KI, Lusis AJ. Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion model. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2806-12. PMID 21979437 DOI: 10.1161/ATVBAHA.111.237420  0.84
2011 Kim JB, Xia YR, Romanoski CE, Lee S, Meng Y, Shi YS, Bourquard N, Gong KW, Port Z, Grijalva V, Reddy ST, Berliner JA, Lusis AJ, Shih DM. Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2624-33. PMID 21836061 DOI: 10.1161/ATVBAHA.111.232827  0.84
2011 Romanoski CE, Che N, Yin F, Mai N, Pouldar D, Civelek M, Pan C, Lee S, Vakili L, Yang WP, Kayne P, Mungrue IN, Araujo JA, Berliner JA, Lusis AJ. Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1. Circulation Research. 109: e27-41. PMID 21737788 DOI: 10.1161/CIRCRESAHA.111.241869  0.84
2011 Besler C, Heinrich K, Rohrer L, Doerries C, Riwanto M, Shih DM, Chroni A, Yonekawa K, Stein S, Schaefer N, Mueller M, Akhmedov A, Daniil G, Manes C, Templin C, ... ... Lusis AJ, et al. Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. The Journal of Clinical Investigation. 121: 2693-708. PMID 21701070 DOI: 10.1172/JCI42946  0.64
2011 Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG, ... ... Lusis AJ, et al. Comparative analysis of proteome and transcriptome variation in mouse. Plos Genetics. 7: e1001393. PMID 21695224 DOI: 10.1371/journal.pgen.1001393  0.84
2011 Civelek M, Lusis AJ. Conducting the metabolic syndrome orchestra. Nature Genetics. 43: 506-8. PMID 21614088 DOI: 10.1038/ng.842  0.84
2011 Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, ... Lusis AJ, et al. Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. Plos Genetics. 7: e1002038. PMID 21490954 DOI: 10.1371/journal.pgen.1002038  0.84
2011 Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, Dugar B, Feldstein AE, Britt EB, Fu X, Chung YM, Wu Y, Schauer P, Smith JD, Allayee H, Tang WH, ... ... Lusis AJ, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature. 472: 57-63. PMID 21475195 DOI: 10.1038/nature09922  0.84
2011 Park CC, Gale GD, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, Horvath S, Lusis AJ, Ophoff RA, Smith DJ. Gene networks associated with conditional fear in mice identified using a systems genetics approach. Bmc Systems Biology. 5: 43. PMID 21410935 DOI: 10.1186/1752-0509-5-43  0.84
2011 Suwanwela J, Farber CR, Haung BL, Song B, Pan C, Lyons KM, Lusis AJ. Systems genetics analysis of mouse chondrocyte differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 747-60. PMID 20954177 DOI: 10.1002/jbmr.271  0.84
2011 Barajas B, Che N, Yin F, Rowshanrad A, Orozco LD, Gong KW, Wang X, Castellani LW, Reue K, Lusis AJ, Araujo JA. NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 58-66. PMID 20947826 DOI: 10.1161/ATVBAHA.110.210906  0.84
2010 Yang X, Peterson L, Thieringer R, Deignan JL, Wang X, Zhu J, Wang S, Zhong H, Stepaniants S, Beaulaurier J, Wang IM, Rosa R, Cumiskey AM, Luo JM, Luo Q, ... ... Lusis AJ, et al. Identification and validation of genes affecting aortic lesions in mice. The Journal of Clinical Investigation. 120: 2414-22. PMID 20577049 DOI: 10.1172/JCI42742  0.84
2010 Yao Y, Bennett BJ, Wang X, Rosenfeld ME, Giachelli C, Lusis AJ, Boström KI. Inhibition of bone morphogenetic proteins protects against atherosclerosis and vascular calcification. Circulation Research. 107: 485-94. PMID 20576934 DOI: 10.1161/CIRCRESAHA.110.219071  0.84
2010 Hsu YH, Zillikens MC, Wilson SG, Farber CR, Demissie S, Soranzo N, Bianchi EN, Grundberg E, Liang L, Richards JB, Estrada K, Zhou Y, van Nas A, Moffatt MF, Zhai G, ... ... Lusis AJ, et al. An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. Plos Genetics. 6: e1000977. PMID 20548944 DOI: 10.1371/journal.pgen.1000977  0.84
2010 Woo JM, Lin Z, Navab M, Van Dyck C, Trejo-Lopez Y, Woo KM, Li H, Castellani LW, Wang X, Iikuni N, Rullo OJ, Wu H, La Cava A, Fogelman AM, Lusis AJ, et al. Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis. Arthritis Research & Therapy. 12: R93. PMID 20482780 DOI: 10.1186/ar3020  0.84
2010 van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS, Schadt EE, Drake T, Lusis AJ. Expression quantitative trait loci: replication, tissue- and sex-specificity in mice. Genetics. 185: 1059-68. PMID 20439777 DOI: 10.1534/genetics.110.116087  0.84
2010 Davis RC, Castellani LW, Hosseini M, Ben-Zeev O, Mao HZ, Weinstein MM, Jung DY, Jun JY, Kim JK, Lusis AJ, Péterfy M. Early hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice. Diabetes. 59: 1616-25. PMID 20393148 DOI: 10.2337/db09-0878  0.84
2010 Tarling EJ, Bojanic DD, Tangirala RK, Wang X, Lovgren-Sandblom A, Lusis AJ, Bjorkhem I, Edwards PA. Impaired development of atherosclerosis in Abcg1-/- Apoe-/- mice: identification of specific oxysterols that both accumulate in Abcg1-/- Apoe-/- tissues and induce apoptosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1174-80. PMID 20299684 DOI: 10.1161/ATVBAHA.110.205617  0.84
2010 Shih DM, Xia YR, Yu JM, Lusis AJ. Temporal and tissue-specific patterns of Pon3 expression in mouse: in situ hybridization analysis. Advances in Experimental Medicine and Biology. 660: 73-87. PMID 20221872 DOI: 10.1007/978-1-60761-350-3_8  0.84
2010 Shaposhnik Z, Wang X, Lusis AJ. Arterial colony stimulating factor-1 influences atherosclerotic lesions by regulating monocyte migration and apoptosis. Journal of Lipid Research. 51: 1962-70. PMID 20194110 DOI: 10.1194/jlr.M005215  0.84
2010 Romanoski CE, Lee S, Kim MJ, Ingram-Drake L, Plaisier CL, Yordanova R, Tilford C, Guan B, He A, Gargalovic PS, Kirchgessner TG, Berliner JA, Lusis AJ. Systems genetics analysis of gene-by-environment interactions in human cells. American Journal of Human Genetics. 86: 399-410. PMID 20170901 DOI: 10.1016/j.ajhg.2010.02.002  0.84
2010 Gargalovic PS, Erbilgin A, Kohannim O, Pagnon J, Wang X, Castellani L, LeBoeuf R, Peterson ML, Spear BT, Lusis AJ. Quantitative trait locus mapping and identification of Zhx2 as a novel regulator of plasma lipid metabolism Circulation: Cardiovascular Genetics. 3: 60-67. PMID 20160197 DOI: 10.1161/CIRCGENETICS.109.902320  0.84
2010 Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, ... ... Lusis AJ, et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Research. 20: 281-90. PMID 20054062 DOI: 10.1101/gr.099234.109  0.84
2010 Lusis AJ, Weiss JN. Cardiovascular networks: systems-based approaches to cardiovascular disease. Circulation. 121: 157-70. PMID 20048233 DOI: 10.1161/CIRCULATIONAHA.108.847699  0.84
2010 Priceman SJ, Sung JL, Shaposhnik Z, Burton JB, Torres-Collado AX, Moughon DL, Johnson M, Lusis AJ, Cohen DA, Iruela-Arispe ML, Wu L. Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy. Blood. 115: 1461-71. PMID 20008303 DOI: 10.1182/blood-2009-08-237412  0.72
2010 Weinstein MM, Yin L, Tu Y, Wang X, Wu X, Castellani LW, Walzem RL, Lusis AJ, Fong LG, Beigneux AP, Young SG. Chylomicronemia elicits atherosclerosis in mice-brief report Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 20-23. PMID 19815815 DOI: 10.1161/ATVBAHA.109.196329  0.84
2009 Wang SS, Martin LJ, Schadt EE, Meng H, Wang X, Zhao W, Ingram-Drake L, Nebohacova M, Mehrabian M, Drake TA, Lusis AJ. Disruption of the aortic elastic lamina and medial calcification share genetic determinants in mice. Circulation. Cardiovascular Genetics. 2: 573-82. PMID 20031637 DOI: 10.1161/CIRCGENETICS.109.860270  0.84
2009 Wu S, Mar-Heyming R, Dugum EZ, Kolaitis NA, Qi H, Pajukanta P, Castellani LW, Lusis AJ, Drake TA. Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice Human Molecular Genetics. 19: 597-608. PMID 19995791 DOI: 10.1093/hmg/ddp526  0.84
2009 Farber CR, Lusis AJ. Future of osteoporosis genetics: enhancing genome-wide association studies. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1937-42. PMID 19888896 DOI: 10.1359/jbmr.091101  0.84
2009 Stoltz DA, Ozer EA, Recker TJ, Estin M, Yang X, Shih DM, Lusis AJ, Zabner J. A common mutation in paraoxonase-2 results in impaired lactonase activity. The Journal of Biological Chemistry. 284: 35564-71. PMID 19840942 DOI: 10.1074/jbc.M109.051706  0.84
2009 Arnold AP, van Nas A, Lusis AJ. Systems biology asks new questions about sex differences. Trends in Endocrinology and Metabolism: Tem. 20: 471-6. PMID 19783453 DOI: 10.1016/j.tem.2009.06.007  0.84
2009 Orozco LD, Cokus SJ, Ghazalpour A, Ingram-Drake L, Wang S, van Nas A, Che N, Araujo JA, Pellegrini M, Lusis AJ. Copy number variation influences gene expression and metabolic traits in mice. Human Molecular Genetics. 18: 4118-29. PMID 19648292 DOI: 10.1093/hmg/ddp360  0.84
2009 Shih DM, Lusis AJ. The roles of PON1 and PON2 in cardiovascular disease and innate immunity. Current Opinion in Lipidology. 20: 288-92. PMID 19474728 DOI: 10.1097/MOL.0b013e32832ca1ee  0.84
2009 White CH, Ohmen JD, Sheth S, Zebboudj AF, McHugh RK, Hoffman LF, Lusis AJ, Davis RC, Friedman RA. Genome-wide screening for genetic loci associated with noise-induced hearing loss. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 207-13. PMID 19337678 DOI: 10.1007/s00335-009-9178-5  0.84
2009 Farber CR, Aten JE, Farber EA, de Vera V, Gularte R, Islas-Trejo A, Wen P, Horvath S, Lucero M, Lusis AJ, Medrano JF. Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling. Physiological Genomics. 37: 294-302. PMID 19336533 DOI: 10.1152/physiolgenomics.90245.2008  0.84
2009 Yang X, Deignan JL, Qi H, Zhu J, Qian S, Zhong J, Torosyan G, Majid S, Falkard B, Kleinhanz RR, Karlsson J, Castellani LW, Mumick S, Wang K, Xie T, ... ... Lusis AJ, et al. Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks. Nature Genetics. 41: 415-23. PMID 19270708 DOI: 10.1038/ng.325  0.84
2009 Bennett BJ, Wang SS, Wang X, Wu X, Lusis AJ. Genetic regulation of atherosclerotic plaque size and morphology in the innominate artery of hyperlipidemic mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 348-55. PMID 19122174 DOI: 10.1161/ATVBAHA.108.176685  0.84
2009 Mungrue IN, Pagnon J, Kohannim O, Gargalovic PS, Lusis AJ. CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade. Journal of Immunology (Baltimore, Md. : 1950). 182: 466-76. PMID 19109178  0.84
2009 Bhasin KK, van Nas A, Martin LJ, Davis RC, Devaskar SU, Lusis AJ. Maternal low-protein diet or hypercholesterolemia reduces circulating essential amino acids and leads to intrauterine growth restriction. Diabetes. 58: 559-66. PMID 19073773 DOI: 10.2337/db07-1530  0.84
2009 Wu S, Lusis AJ, Drake TA. A systems-based framework for understanding complex metabolic and cardiovascular disorders. Journal of Lipid Research. 50: S358-63. PMID 19033210 DOI: 10.1194/jlr.R800067-JLR200  0.84
2009 Shaposhnik Z, Wang X, Trias J, Fraser H, Lusis AJ. The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002). Journal of Lipid Research. 50: 623-9. PMID 19029066 DOI: 10.1194/jlr.M800361-JLR200  0.84
2009 van Nas A, Guhathakurta D, Wang SS, Yehya N, Horvath S, Zhang B, Ingram-Drake L, Chaudhuri G, Schadt EE, Drake TA, Arnold AP, Lusis AJ. Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. Endocrinology. 150: 1235-49. PMID 18974276 DOI: 10.1210/en.2008-0563  0.84
2009 Farber CR, van Nas A, Ghazalpour A, Aten JE, Doss S, Sos B, Schadt EE, Ingram-Drake L, Davis RC, Horvath S, Smith DJ, Drake TA, Lusis AJ. An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 105-16. PMID 18767929 DOI: 10.1359/jbmr.080908  0.84
2009 Smith DJ, Lusis AJ. Genomic Approaches to Complex Disease Genomic and Personalized Medicine, Two-Vol Set. 33-46. DOI: 10.1016/B978-0-12-369420-1.00003-2  0.84
2008 Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, ... ... Lusis AJ, et al. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. Plos One. 3: e3583. PMID 18974833 DOI: 10.1371/journal.pone.0003583  0.84
2008 Lusis AJ, Attie AD, Reue K. Metabolic syndrome: from epidemiology to systems biology. Nature Reviews. Genetics. 9: 819-30. PMID 18852695 DOI: 10.1038/nrg2468  0.48
2008 Allayee H, Baylin A, Hartiala J, Wijesuriya H, Mehrabian M, Lusis AJ, Campos H. Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction. The American Journal of Clinical Nutrition. 88: 934-40. PMID 18842779  0.84
2008 Ghazalpour A, Doss S, Kang H, Farber C, Wen PZ, Brozell A, Castellanos R, Eskin E, Smith DJ, Drake TA, Lusis AJ. High-resolution mapping of gene expression using association in an outbred mouse stock. Plos Genetics. 4: e1000149. PMID 18688273 DOI: 10.1371/journal.pgen.1000149  0.84
2008 Chen J, Hui ST, Couto FM, Mungrue IN, Davis DB, Attie AD, Lusis AJ, Davis RA, Shalev A. Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3581-94. PMID 18552236 DOI: 10.1096/fj.08-111690  0.48
2008 Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, ... ... Lusis AJ, et al. Mapping the genetic architecture of gene expression in human liver. Plos Biology. 6: e107. PMID 18462017 DOI: 10.1371/journal.pbio.0060107  0.84
2008 Oskolkova OV, Afonyushkin T, Leitner A, von Schlieffen E, Gargalovic PS, Lusis AJ, Binder BR, Bochkov VN. ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response. Blood. 112: 330-9. PMID 18451308 DOI: 10.1182/blood-2007-09-112870  0.84
2008 Aten JE, Fuller TF, Lusis AJ, Horvath S. Using genetic markers to orient the edges in quantitative trait networks: the NEO software. Bmc Systems Biology. 2: 34. PMID 18412962 DOI: 10.1186/1752-0509-2-34  0.84
2008 Park CC, Ahn S, Bloom JS, Lin A, Wang RT, Wu T, Sekar A, Khan AH, Farr CJ, Lusis AJ, Leahy RM, Lange K, Smith DJ. Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids. Nature Genetics. 40: 421-9. PMID 18362883 DOI: 10.1038/ng.113  0.84
2008 Farber CR, Lusis AJ. Integrating global gene expression analysis and genetics. Advances in Genetics. 60: 571-601. PMID 18358333 DOI: 10.1016/S0065-2660(07)00420-8  0.84
2008 Bhattacharyya T, Nicholls SJ, Topol EJ, Zhang R, Yang X, Schmitt D, Fu X, Shao M, Brennan DM, Ellis SG, Brennan ML, Allayee H, Lusis AJ, Hazen SL. Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. Jama. 299: 1265-76. PMID 18349088 DOI: 10.1001/jama.299.11.1265  0.84
2008 Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, ... ... Lusis AJ, et al. Variations in DNA elucidate molecular networks that cause disease. Nature. 452: 429-35. PMID 18344982 DOI: 10.1038/nature06757  0.84
2008 Lusis AJ, Pajukanta P. A treasure trove for lipoprotein biology Nature Genetics. 40: 129-130. PMID 18227868 DOI: 10.1038/ng0208-129  0.84
2008 Araujo JA, Barajas B, Kleinman M, Wang X, Bennett BJ, Gong KW, Navab M, Harkema J, Sioutas C, Lusis AJ, Nel AE. Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress. Circulation Research. 102: 589-96. PMID 18202315 DOI: 10.1161/CIRCRESAHA.107.164970  0.84
2008 Chen J, Saxena G, Mungrue IN, Lusis AJ, Shalev A. Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis. Diabetes. 57: 938-44. PMID 18171713 DOI: 10.2337/db07-0715  0.84
2008 McLin JP, Thompson LM, Lusis AJ, Davis RC, Steward O. Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid. Neurobiology of Disease. 29: 391-9. PMID 17996456 DOI: 10.1016/j.nbd.2007.10.002  0.84
2007 Péterfy M, Davis RC, Lusis AJ. Metabolic syndrome as a modifier of atherosclerosis in murine models. Current Drug Targets. 8: 1215-20. PMID 18045100 DOI: 10.2174/138945007782403838  0.84
2007 Bennett BJ, Romanoski CE, Lusis AJ. Network-centered view of coronary artery disease. Expert Review of Cardiovascular Therapy. 5: 1095-103. PMID 18035925 DOI: 10.1586/14779072.5.6.1095  0.84
2007 Wang SS, Shi W, Wang X, Velky L, Greenlee S, Wang MT, Drake TA, Lusis AJ. Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2671-6. PMID 17916774 DOI: 10.1161/ATVBAHA.107.148106  0.84
2007 Lusis AJ, Yu J, Wang SS. The problem of passenger genes in transgenic mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2100-3. PMID 17690316 DOI: 10.1161/ATVBAHA.107.147918  0.84
2007 Lee JC, Weissglas-Volkov D, Kyttälä M, Sinsheimer JS, Jokiaho A, de Bruin TW, Lusis AJ, Brennan ML, van Greevenbroek MM, van der Kallen CJ, Hazen SL, Pajukanta P. USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2222-7. PMID 17673701 DOI: 10.1161/ATVBAHA.107.151530  0.84
2007 Fuller TF, Ghazalpour A, Aten JE, Drake TA, Lusis AJ, Horvath S. Weighted gene coexpression network analysis strategies applied to mouse weight. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 463-72. PMID 17668265 DOI: 10.1007/s00335-007-9043-3  0.84
2007 Gong KW, Zhao W, Li N, Barajas B, Kleinman M, Sioutas C, Horvath S, Lusis AJ, Nel A, Araujo JA. Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome Biology. 8: R149. PMID 17655762 DOI: 10.1186/gb-2007-8-7-r149  0.68
2007 Wang SS, Schadt EE, Wang H, Wang X, Ingram-Drake L, Shi W, Drake TA, Lusis AJ. Identification of pathways for atherosclerosis in mice: integration of quantitative trait locus analysis and global gene expression data. Circulation Research. 101: e11-30. PMID 17641228 DOI: 10.1161/CIRCRESAHA.107.152975  0.84
2007 Orozco LD, Kapturczak MH, Barajas B, Wang X, Weinstein MM, Wong J, Deshane J, Bolisetty S, Shaposhnik Z, Shih DM, Agarwal A, Lusis AJ, Araujo JA. Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis. Circulation Research. 100: 1703-11. PMID 17495224 DOI: 10.1161/CIRCRESAHA.107.151720  0.84
2007 Gharavi NM, Gargalovic PS, Chang I, Araujo JA, Clark MJ, Szeto WL, Watson AD, Lusis AJ, Berliner JA. High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1346-53. PMID 17379837 DOI: 10.1161/ATVBAHA.107.141283  0.84
2007 Shih DM, Xia YR, Wang XP, Wang SS, Bourquard N, Fogelman AM, Lusis AJ, Reddy ST. Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice. Circulation Research. 100: 1200-7. PMID 17379834 DOI: 10.1161/01.RES.0000264499.48737.69  0.84
2007 Meng H, Vera I, Che N, Wang X, Wang SS, Ingram-Drake L, Schadt EE, Drake TA, Lusis AJ. Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics. Proceedings of the National Academy of Sciences of the United States of America. 104: 4530-5. PMID 17360558 DOI: 10.1073/pnas.0607620104  0.84
2007 Itoh Y, Melamed E, Yang X, Kampf K, Wang S, Yehya N, Van Nas A, Replogle K, Band MR, Clayton DF, Schadt EE, Lusis AJ, Arnold AP. Dosage compensation is less effective in birds than in mammals. Journal of Biology. 6: 2. PMID 17352797 DOI: 10.1186/jbiol53  0.84
2007 Shaposhnik Z, Wang X, Weinstein M, Bennett BJ, Lusis AJ. Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 621-7. PMID 17158354 DOI: 10.1161/01.ATV.0000254673.55431.e6  0.84
2007 Stoltz DA, Ozer EA, Ng CJ, Yu JM, Reddy ST, Lusis AJ, Bourquard N, Parsek MR, Zabner J, Shih DM. Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L852-60. PMID 17122353 DOI: 10.1152/ajplung.00370.2006  0.84
2006 Parks BW, Lusis AJ, Kabarowski JH. Loss of the lysophosphatidylcholine effector, G2A, ameliorates aortic atherosclerosis in low-density lipoprotein receptor knockout mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2703-9. PMID 16990555 DOI: 10.1161/01.ATV.0000246774.02426.71  0.84
2006 Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, Brozell A, Schadt EE, Drake TA, Lusis AJ, Horvath S. Integrating genetic and network analysis to characterize genes related to mouse weight. Plos Genetics. 2: e130. PMID 16934000 DOI: 10.1371/journal.pgen.0020130  0.84
2006 Lusis AJ. A thematic review series: Systems biology approaches to metabolic and cardiovascular disorders Journal of Lipid Research. 47: 1887-1890. PMID 16924129 DOI: 10.1194/jlr.E600004-JLR200  0.84
2006 Estrada-Smith D, Collins AR, Wang X, Crockett C, Castellani L, Lusis AJ, Davis RC. Impact of chromosome 2 obesity loci on cardiovascular complications of insulin resistance in LDL receptor-deficient C57BL/6 mice. Diabetes. 55: 2265-71. PMID 16873689 DOI: 10.2337/db06-0377  0.84
2006 Drake TA, Schadt EE, Lusis AJ. Integrating genetic and gene expression data: Application to cardiovascular and metabolic traits in mice Mammalian Genome. 17: 466-479. PMID 16783628 DOI: 10.1007/s00335-005-0175-z  0.84
2006 Bhasin KK, Yu JM, Tward A, Shih D, Campbell DA, Lusis AJ. Trypanosoma congolense: paraoxonase 1 prolongs survival of infected mice. Experimental Parasitology. 114: 240-5. PMID 16682028 DOI: 10.1016/j.exppara.2006.03.010  0.36
2006 Castellani LW, Chang JJ, Wang X, Lusis AJ, Reynolds WF. Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males. Journal of Lipid Research. 47: 1366-77. PMID 16639078 DOI: 10.1194/jlr.M600005-JLR200  0.84
2006 Ghazalpour A, Wang X, Lusis AJ, Mehrabian M. Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice. Genetics. 173: 943-51. PMID 16624897 DOI: 10.1534/genetics.106.057455  0.84
2006 Sheth SS, Bodnar JS, Ghazalpour A, Thipphavong CK, Tsutsumi S, Tward AD, Demant P, Kodama T, Aburatani H, Lusis AJ. Hepatocellular carcinoma in Txnip-deficient mice. Oncogene. 25: 3528-36. PMID 16607285 DOI: 10.1038/sj.onc.1209394  0.84
2006 Lee JC, Lusis AJ, Pajukanta P. Familial combined hyperlipidemia: Upstream transcription factor 1 and beyond Current Opinion in Lipidology. 17: 101-109. PMID 16531745 DOI: 10.1097/01.mol.0000217890.54875.13  0.84
2006 Wang S, Yehya N, Schadt EE, Wang H, Drake TA, Lusis AJ. Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity Plos Genetics. 2. PMID 16462940 DOI: 10.1371/journal.pgen.0020015  0.84
2005 Drake TA, Schadt EE, Davis RC, Lusis AJ. Integrating genetic and gene expression data to study the metabolic syndrome and diabetes in mice. American Journal of Therapeutics. 12: 503-11. PMID 16280644 DOI: 10.1097/01.mjt.0000178775.39149.64  0.84
2005 Davis RC, Schadt EE, Smith DJ, Hsieh EW, Cervino AC, van Nas A, Rosales M, Doss S, Meng H, Allayee H, Lusis AJ. A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background. Genomics. 86: 259-70. PMID 16039824 DOI: 10.1016/j.ygeno.2005.05.010  0.84
2005 Ghazalpour A, Doss S, Sheth SS, Ingram-Drake LA, Schadt EE, Lusis AJ, Drake TA. Genomic analysis of metabolic pathway gene expression in mice. Genome Biology. 6: R59. PMID 15998448 DOI: 10.1186/gb-2005-6-7-r59  0.84
2005 Doss S, Schadt EE, Drake TA, Lusis AJ. Cis-acting expression quantitative trait loci in mice. Genome Research. 15: 681-91. PMID 15837804 DOI: 10.1101/gr.3216905  0.84
2005 Parks BW, Gambill GP, Lusis AJ, Kabarowski JH. Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice. Journal of Lipid Research. 46: 1405-15. PMID 15834123 DOI: 10.1194/jlr.M500085-JLR200  0.84
2005 Davis RC, Schadt EE, Cervino AC, Péterfy M, Lusis AJ. Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility. Diabetes. 54: 1191-9. PMID 15793261 DOI: 10.2337/diabetes.54.4.1191  0.84
2005 Nguyen HX, Lusis AJ, Tidball JG. Null mutation of myeloperoxidase in mice prevents mechanical activation of neutrophil lysis of muscle cell membranes in vitro and in vivo. The Journal of Physiology. 565: 403-13. PMID 15790660 DOI: 10.1113/jphysiol.2005.085506  0.84
2005 Sheth SS, Castellani LW, Chari S, Wagg C, Thipphavong CK, Bodnar JS, Tontonoz P, Attie AD, Lopaschuk GD, Lusis AJ. Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition. Journal of Lipid Research. 46: 123-34. PMID 15520447 DOI: 10.1194/jlr.M400341-JLR200  0.52
2004 Lusis AJ, Mar R, Pajukanta P. Genetics of atherosclerosis. Annual Review of Genomics and Human Genetics. 5: 189-218. PMID 15485348 DOI: 10.1146/annurev.genom.5.061903.175930  0.84
2004 Lusis AJ, Fogelman AM, Fonarow GC. Genetic basis of atherosclerosis: Part II - Clinical implications Circulation. 110: 2066-2071. PMID 15466657 DOI: 10.1161/01.CIR.0000143098.98869.F8  0.84
2004 Lusis AJ, Fogelman AM, Fonarow GC. Genetic basis of atherosclerosis: Part I. New genes and pathways Circulation. 110: 1868-1873. PMID 15451808 DOI: 10.1161/01.CIR.0000143041.58692.CC  0.84
2004 Cantor RM, de Bruin T, Kono N, Napier S, van Nas A, Allayee H, Lusis AJ. Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1935-41. PMID 15308552 DOI: 10.1161/01.ATV.0000142358.46276.a7  0.84
2004 Ghazalpour A, Doss S, Yang X, Aten J, Toomey EM, Van Nas A, Wang S, Drake TA, Lusis AJ. Thematic review series: The pathogenesis of atherosclerosis. Toward a biological network for atherosclerosis. Journal of Lipid Research. 45: 1793-805. PMID 15292376 DOI: 10.1194/jlr.R400006-JLR200  0.84
2004 Donnelly KL, Margosian MR, Sheth SS, Lusis AJ, Parks EJ. Increased lipogenesis and fatty acid reesterification contribute to hepatic triacylglycerol stores in hyperlipidemic Txnip-/- mice. The Journal of Nutrition. 134: 1475-80. PMID 15173414  0.84
2004 Hui TY, Sheth SS, Diffley JM, Potter DW, Lusis AJ, Attie AD, Davis RA. Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. The Journal of Biological Chemistry. 279: 24387-93. PMID 15047687 DOI: 10.1074/jbc.M401280200  0.52
2004 Shi W, Wang X, Wong J, Hedrick CC, Wong H, Castellani LW, Lusis AJ. Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice. Biochemical and Biophysical Research Communications. 317: 223-9. PMID 15047172 DOI: 10.1016/j.bbrc.2004.03.037  0.84
2004 Estrada-Smith D, Castellani LW, Wong H, Wen PZ, Chui A, Lusis AJ, Davis RC. Dissection of multigenic obesity traits in congenic mouse strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 14-22. PMID 14727138 DOI: 10.1007/s00335-003-2294-8  0.84
2003 MacLellan WR, Lusis AJ. Dilated cardiomyopathy: Learning to live with yourself Nature Medicine. 9: 1455-1456. PMID 14647516 DOI: 10.1038/nm1203-1455  0.84
2003 Lusis AJ. Genetic factors in cardiovascular disease: 10 Questions Trends in Cardiovascular Medicine. 13: 309-316. PMID 14596945 DOI: 10.1016/j.tcm.2003.08.001  0.84
2003 Colinayo VV, Qiao JH, Wang X, Krass KL, Schadt E, Lusis AJ, Drake TA. Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 464-71. PMID 12925895 DOI: 10.1007/s00335-002-2187-2  0.84
2003 Allayee H, Ghazalpour A, Lusis AJ. Using mice to dissect genetic factors in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1501-9. PMID 12920046 DOI: 10.1161/01.ATV.0000090886.40027.DC  0.84
2003 Araujo JA, Meng L, Tward AD, Hancock WW, Zhai Y, Lee A, Ishikawa K, Iyer S, Buelow R, Busuttil RW, Shih DM, Lusis AJ, Kupiec-Weglinski JW. Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse. Journal of Immunology (Baltimore, Md. : 1950). 171: 1572-80. PMID 12874251  0.68
2003 Krass KL, Colinayo V, Ghazalpour A, Vinters HV, Lusis AJ, Drake TA. Genetic loci contributing to age-related hippocampal lesions in mice. Neurobiology of Disease. 13: 102-8. PMID 12828934 DOI: 10.1016/S0969-9961(03)00034-2  0.84
2003 Pajukanta P, Allayee H, Krass KL, Kuraishy A, Soro A, Lilja HE, Mar R, Taskinen MR, Nuotio I, Laakso M, Rotter JI, de Bruin TW, Cantor RM, Lusis AJ, Peltonen L. Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q. American Journal of Human Genetics. 72: 903-17. PMID 12638083 DOI: 10.1086/374177  0.84
2002 Smith JB, Wadleigh DJ, Xia YR, Mar RA, Herschman HR, Lusis AJ. Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5. Immunogenetics. 54: 599-603. PMID 12439624 DOI: 10.1007/s00251-002-0501-5  0.84
2002 Smith DJ, Lusis AJ. The allelic structure of common disease. Human Molecular Genetics. 11: 2455-61. PMID 12351581  0.84
2002 Colinayo VV, Qiao JH, Demant P, Krass K, Lusis AJ, Drake TA. Genetic characterization of the Dyscalc locus. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 283-8. PMID 12115029 DOI: 10.1007/s00335-001-2148-1  0.84
2002 Eiserich JP, Baldus S, Brennan ML, Ma W, Zhang C, Tousson A, Castro L, Lusis AJ, Nauseef WM, White CR, Freeman BA. Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science (New York, N.Y.). 296: 2391-4. PMID 12089442 DOI: 10.1126/science.1106830  0.84
2002 Allayee H, Krass KL, Pajukanta P, Cantor RM, van der Kallen CJ, Mar R, Rotter JI, de Bruin TW, Peltonen L, Lusis AJ. Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia. Circulation Research. 90: 926-31. PMID 11988495 DOI: 10.1161/01.RES.0000015885.27134.F0  0.84
2002 Shi W, Wang X, Tangchitpiyanond K, Wong J, Shi Y, Lusis AJ. Atherosclerosis in C3H/HeJ mice reconstituted with apolipoprotein E-null bone marrow Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 650-655. PMID 11950705 DOI: 10.1161/01.ATV.0000013388.03553.31  0.84
2002 Gukovskaya AS, Vaquero E, Zaninovic V, Gorelick FS, Lusis AJ, Brennan ML, Holland S, Pandol SJ. Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. Gastroenterology. 122: 974-84. PMID 11910350  0.84
2002 Sheth SS, Deluna A, Allayee H, Lusis AJ. Understanding atherosclerosis through mouse genetics. Current Opinion in Lipidology. 13: 181-9. PMID 11891421 DOI: 10.1097/00041433-200204000-00010  0.84
2002 Brennan ML, Wu W, Fu X, Shen Z, Song W, Frost H, Vadseth C, Narine L, Lenkiewicz E, Borchers MT, Lusis AJ, Lee JJ, Lee NA, Abu-Soud HM, Ischiropoulos H, et al. A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species. The Journal of Biological Chemistry. 277: 17415-27. PMID 11877405 DOI: 10.1074/jbc.M112400200  0.84
2002 Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, ... Lusis AJ, et al. Positional cloning of the combined hyperlipidemia gene Hyplip1. Nature Genetics. 30: 110-6. PMID 11753387 DOI: 10.1038/ng811  0.84
2001 Baldus S, Eiserich JP, Mani A, Castro L, Figueroa M, Chumley P, Ma W, Tousson A, White CR, Bullard DC, Brennan ML, Lusis AJ, Moore KP, Freeman BA. Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. The Journal of Clinical Investigation. 108: 1759-70. PMID 11748259 DOI: 10.1172/JCI12617  0.84
2001 Castellani LW, Lusis AJ. ApoA-II versus ApoA-I: two for one is not always a good deal. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1870-2. PMID 11742857  0.84
2001 Van Lenten BJ, Navab M, Shih D, Fogelman AM, Lusis AJ. The role of high-density lipoproteins in oxidation and inflammation Trends in Cardiovascular Medicine. 11: 155-161. PMID 11686006 DOI: 10.1016/S1050-1738(01)00095-0  0.84
2001 Allayee H, de Bruin TW, Michelle Dominguez K, Cheng LS, Ipp E, Cantor RM, Krass KL, Keulen ET, Aouizerat BE, Lusis AJ, Rotter JI. Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p. Hypertension. 38: 773-8. PMID 11641285  0.84
2001 Gaut JP, Yeh GC, Tran HD, Byun J, Henderson JP, Richter GM, Brennan ML, Lusis AJ, Belaaouaj A, Hotchkiss RS, Heinecke JW. Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis. Proceedings of the National Academy of Sciences of the United States of America. 98: 11961-6. PMID 11593004 DOI: 10.1073/pnas.211190298  0.84
2001 Mehrabian M, Wong J, Wang X, Jiang Z, Shi W, Fogelman AM, Lusis AJ. Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia. Circulation Research. 89: 125-30. PMID 11463718  0.8
2001 Hedrick CC, Castellani LW, Wong H, Lusis AJ. In vivo interactions of apoA-II, apoA-I, and hepatic lipase contributing to HDL structure and antiatherogenic functions. Journal of Lipid Research. 42: 563-70. PMID 11290828  0.84
2001 Pajukanta P, Bodnar JS, Sallinen R, Chu M, Airaksinen T, Xiao Q, Castellani LW, Sheth SS, Wessman M, Palotie A, Sinsheimer JS, Demant P, Lusis AJ, Peltonen L. Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 238-45. PMID 11252174 DOI: 10.1007/s003350010265  0.84
2001 Castellani LW, Goto AM, Lusis AJ. Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance. Diabetes. 50: 643-51. PMID 11246886  0.84
2001 Brennan ML, Anderson MM, Shih DM, Qu XD, Wang X, Mehta AC, Lim LL, Shi W, Hazen SL, Jacob JS, Crowley JR, Heinecke JW, Lusis AJ. Increased atherosclerosis in myeloperoxidase-deficient mice. The Journal of Clinical Investigation. 107: 419-30. PMID 11181641 DOI: 10.1172/JCI8797  0.84
2001 Brennan ML, Gaur A, Pahuja A, Lusis AJ, Reynolds WF. Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 112: 97-105. PMID 11108938 DOI: 10.1016/S0165-5728(00)00392-1  0.84
2000 Allayee H, Laffitte BA, Lusis AJ. An absorbing study of cholesterol Science. 290: 1709-1711. PMID 11186392 DOI: 10.1126/science.290.5497.1709  0.84
2000 Villa-Colinayo V, Shi W, Araujo J, Lusis AJ. Genetics of atherosclerosis: the search for genes acting at the level of the vessel wall Current Atherosclerosis Reports. 2: 380-389. PMID 11122769  0.84
2000 Shi W, Wang X, Wang NJ, McBride WH, Lusis AJ. Effect of macrophage-derived apolipoprotein E on established atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2261-6. PMID 11031213  0.84
2000 Lusis AJ. Atherosclerosis Nature. 407: 233-241. PMID 11001066 DOI: 10.1038/35025203  0.84
2000 Widney DP, Xia YR, Lusis AJ, Smith JB. The murine chemokine CXCL11 (IFN-inducible T cell α chemoattractant) is an IFN-γ- and lipopolysaccharide-inducible glucocorticoid-attenuated response gene expressed in lung and other tissues during endotoxemia Journal of Immunology. 164: 6322-6331. PMID 10843686  0.84
1999 Aouizerat BE, Allayee H, Bodnar J, Krass KL, Peltonen L, de Bruin TW, Rotter JI, Lusis AJ. Novel genes for familial combined hyperlipidemia. Current Opinion in Lipidology. 10: 113-22. PMID 10327279 DOI: 10.1097/00041433-199904000-00005  0.84
1999 Shih PT, Brennan ML, Vora DK, Territo MC, Strahl D, Elices MJ, Lusis AJ, Berliner JA. Blocking very late antigen-4 integrin decreases leukocyte entry and fatty streak formation in mice fed an atherogenic diet. Circulation Research. 84: 345-51. PMID 10024309  0.84
1999 Gu L, Johnson MW, Lusis AJ. Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: Interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 442-453. PMID 9974430  0.84
1998 Jiang Z, Shih DM, Xia YR, Lusis AJ, de Beer FC, de Villiers WJ, van der Westhuyzen DR, de Beer MC. Structure, organization, and chromosomal mapping of the gene encoding macrosialin, a macrophage-restricted protein. Genomics. 50: 199-205. PMID 9653646 DOI: 10.1006/geno.1998.5327  0.84
1998 Mehrabian M, Wen PZ, Fisler J, Davis RC, Lusis AJ. Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model. The Journal of Clinical Investigation. 101: 2485-96. PMID 9616220 DOI: 10.1172/JCI1748  0.56
1998 Tabor DE, Xia YR, Mehrabian M, Edwards PA, Lusis AJ. A cluster of stearoyl CoA desaturase genes, Scd1 and Scd2, on mouse chromosome 19. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 341-2. PMID 9530639 DOI: 10.1007/s003359900765  0.56
1998 Briquet-Laugier V, Xia YR, Rooke K, Mehrabian M, Lusis AJ, Doolittle MH. Mapping of three members of the mouse protien disulfide isomerase family Mammalian Genome. 9: 176-177. PMID 9457688 DOI: 10.1007/s003359900717  0.56
1998 Heinecke JW, Lusis AJ. Paraoxonase-gene polymorphisms associated with coronary heart disease: support for the oxidative damage hypothesis? American Journal of Human Genetics. 62: 20-4. PMID 9443884 DOI: 10.1086/301691  0.84
1998 Welch CL, Xia YR, Edwards PA, Lusis AJ, Ericsson J. Assignment of Gpam to distal mouse chromosome 19 by linkage analysis. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 93. PMID 9434961 DOI: 10.1007/s003359900694  0.4
1997 Rooke K, Briquet-Laugier V, Xia YR, Lusis AJ, Doolittle MH. Mapping of the gene for calreticulin (Calr) to mouse chromosome 8 Mammalian Genome. 8: 870-871. PMID 9337407 DOI: 10.1007/s003359900599  0.4
1997 Klingenspor M, Bodnar J, Welch C, Xia YR, Lusis AJ, Reue K. Localization of ubiquitin gene family members to mouse chromosomes 5, 11, and 18 Mammalian Genome. 8: 789-790. PMID 9321482 DOI: 10.1007/s003359900572  0.4
1997 Ishikawa K, Navab M, Leitinger N, Fogelman AM, Lusis AJ. Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL Journal of Clinical Investigation. 100: 1209-1216. PMID 9276739  0.56
1997 Welch CL, Xia YR, Hong H, Stallcup MR, Lusis AJ. Localization of the mouse glucocorticoid receptor-interacting protein 1 gene (Grip1) to proximal Chromosome 1 by linkage analysis Mammalian Genome. 8: 620-621. PMID 9250876 DOI: 10.1007/s003359900519  0.4
1997 Castellani LW, Navab M, Van Lenten BJ, Hedrick CC, Hama SY, Goto AM, Fogelman AM, Lusis AJ. Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles. The Journal of Clinical Investigation. 100: 464-74. PMID 9218525 DOI: 10.1172/JCI119554  0.8
1997 Klingenspor M, Bodnar J, Xia YR, Welch C, Lusis AJ, Reue K. Localization of profilin-1 (Pfn1) and a related sequence (Pfn1-rs) to mouse chromosomes 11 and 15 respectively Mammalian Genome. 8: 539-540. PMID 9196007 DOI: 10.1007/s003359900496  0.4
1997 Navab M, Hama-Levy S, Van Lenten BJ, Fonarow GC, Cardinez CJ, Castellani LW, Brennan ML, Lusis AJ, Fogelman AM, La Du BN. Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio. The Journal of Clinical Investigation. 99: 2005-19. PMID 9109446 DOI: 10.1172/JCI119369  0.84
1997 Machleder D, Ivandic B, Welch C, Castellani L, Reue K, Lusis AJ. Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism Journal of Clinical Investigation. 99: 1406-1419. PMID 9077551  0.84
1997 Shau H, Kim AT, Hedrick CC, Lusis AJ, Tompkins C, Finney R, Leung DW, Paglia DE. Endogenous natural killer enhancing factor-B increases cellular resistance to oxidative stresses. Free Radical Biology & Medicine. 22: 497-507. PMID 8981042 DOI: 10.1016/S0891-5849(96)00372-3  0.84
1996 Welch CL, Xia YR, Billheimer JT, Strauss JF, Lusis AJ. Assignment of the mouse sterol carrier protein gene (Scp2) to Chromosome 4 Mammalian Genome. 7: 624. PMID 8678992  0.4
1996 Cohen RD, Welch C, Xia YR, Lusis AJ, Reue K. Localization of mouse peroxisome proliferator-activated receptor δ (Ppard) on Chromosome 17 near colipase (Clps) Mammalian Genome. 7: 557-558. PMID 8672143  0.4
1996 Mehdizadeh S, Warden CH, Wen PZ, Xia YR, Mehrabian M, Lusis AJ. The glutathione peroxidase gene, Gpx1, maps to mouse Chromosome 9 Mammalian Genome. 7: 465-466. PMID 8662233  0.56
1996 Reue K, Xia YR, Shi VW, Cohen RD, Welch C, Lusis AJ. Localization of mouse peroxisome proliferator-activated receptor γ on Chromosome 6 Mammalian Genome. 7: 390-391. PMID 8661743  0.4
1996 Ivandic BT, Qiao JH, Machleder D, Liao F, Drake TA, Lusis AJ. A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice Proceedings of the National Academy of Sciences of the United States of America. 93: 5483-5488. PMID 8643601 DOI: 10.1073/pnas.93.11.5483  0.84
1996 Boring L, Gosling J, Monteclaro FS, Lusis AJ, Tsou CL, Charo IF. Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1α receptors: Evidence for two closely linked C-C chemokine receptors on chromosome 9 Journal of Biological Chemistry. 271: 7551-7558. PMID 8631787  0.84
1996 Henning SM, Swendseid ME, Ivandic BT, Lusis AJ. A methyl/folate-deficient diet causes oxidative stress Faseb Journal. 10.  0.84
1996 Kama S, Debeer FC, Lusis AJ, Navab M, Fogelman AM. Secretory phospholipase A2 converts the anti-inflammatory high density lipoprotein to a pro-inflammatory particle Faseb Journal. 10.  0.84
1996 Hama S, Harris B, Navab M, Drinkwater DC, Lusis AJ, Fogbman AM. Erythrocytes from fatty streak prone mice on atherogenic diet are highly susceptible to lysis by mildly oxidized LDL Faseb Journal. 10.  0.84
1995 Shih DM, Welch C, Lusis AJ. New insights into atherosclerosis from studies with mouse models Molecular Medicine Today. 1: 364-372. PMID 9415182  0.84
1995 Fyfe AI, Ardehali A, Laks H, Drinkwater DC, Lusis AJ. Biologic modification of the immune response in mouse cardiac isografts using gene transfer. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 14: S165-70. PMID 8719479  0.84
1995 Liao F, Andalibi A, Lusis AJ, Fogelman AM. Genetic control of the inflammatory response induced by oxidized lipids The American Journal of Cardiology. 75. PMID 7863978 DOI: 10.1016/0002-9149(95)80015-K  0.84
1995 DeMeester CA, Bu X, Gray RJ, Lusis AJ, Rotter JI. Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus American Journal of Human Genetics. 56: 287-293. PMID 7825589  0.84
1995 Van Lenten BJ, Prieve J, Navab M, Hama S, Lusis AJ, Fogelman AM. Lipid-induced changes in intracellular iron homeostasis in vitro and in vivo Journal of Clinical Investigation. 95: 2104-2110. PMID 7738177  0.84
1995 Ardehali A, Fyfe A, Laks H, Drinkwater DC, Qiao JH, Lusis AJ. Direct gene transfer into donor hearts at the time of harvest. The Journal of Thoracic and Cardiovascular Surgery. 109: 716-9; discussion 71. PMID 7715219 DOI: 10.1016/S0022-5223(95)70353-5  0.52
1995 Qiao JH, Fishbein MC, Demer LL, Lusis AJ. Genetic determination of cartilaginous metaplasia in mouse aorta Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2265-2272. PMID 7489252  0.84
1994 Hedrick CC, Lusis AJ. Apolipoprotein A-II: A protein in search of a function Canadian Journal of Cardiology. 10: 453-459. PMID 8193990  0.84
1994 Marbois BN, Xia YR, Lusis AJ, Clarke CF. Ubiquinone biosynthesis in eukaryotic cells: tissue distribution of mRNA encoding 3,4-dihydroxy-5-polyprenylbenzoate methyltransferase in the rat and mapping of the COQ3 gene to mouse chromosome 4. Archives of Biochemistry and Biophysics. 313: 83-8. PMID 8053692 DOI: 10.1006/abbi.1994.1362  0.4
1994 Liao F, Andalibi A, Qiao JH, Allayee H, Fogelman AM, Lusis AJ. Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice Journal of Clinical Investigation. 94: 877-884. PMID 8040344  0.84
1994 Fyfe AI, Qiao JH, Lusis AJ. Immune-deficient mice develop typical atherosclerotic fatty streaks when fed an atherogenic diet. The Journal of Clinical Investigation. 94: 2516-20. PMID 7989611 DOI: 10.1172/JCI117622  0.84
1994 Watson JB, Coulter PM, Xia YR, Lusis AJ. Mouse chromosomal localization of the cortexin (Ctxn) gene. Genomics. 22: 251-2. PMID 7959786 DOI: 10.1006/geno.1994.1379  0.4
1994 LeBoeuf RC, Xia YR, Oram JF, Lusis AJ. Mapping of the Gene for High-Density Lipoprotein Binding Protein (Hdlbp) to Proximal Mouse Chromosome 1 Genomics. 23: 296-298. PMID 7829095 DOI: 10.1006/geno.1994.1501  0.84
1994 Hyman RW, Frank S, Warden CH, Daluiski A, Heller R, Lusis AJ. Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice. Biochemical Genetics. 32: 397-407. PMID 7748156 DOI: 10.1007/BF00566060  0.84
1993 Fisler JS, Warden CH, Pace MJ, Lusis AJ. BSB: a new mouse model of multigenic obesity. Obesity Research. 1: 271-80. PMID 16353357  0.84
1993 Liao F, Andalibi A, DeBeer FC, Fogelman AM, Lusis AJ. Genetic control of inflammatory gene induction and NF-κB-like transcription factor activation in response to an atherogenic diet in mice Journal of Clinical Investigation. 91: 2572-2579. PMID 8514869  0.84
1993 Andalibi A, Diep A, Quon D, Mohandas T, Taylor BA, Lusis AJ. Mapping of multiple mouse loci related to the farnesyl pyrophosphate synthetase gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 211-9. PMID 8499655 DOI: 10.1007/BF00417565  0.84
1993 Qiao JH, Castellani LW, Fishbein MC, Lusis AJ. Immune-complex-mediated vasculitis increases coronary artery lipid accumulation in autoimmune-prone MRL mice Arteriosclerosis, Thrombosis, and Vascular Biology. 13: 932-943. PMID 8499414  0.52
1993 Shieh BH, Sparkes RS, Gaynor RB, Lusis AJ. Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23. Genomics. 16: 266-8. PMID 8486371 DOI: 10.1006/geno.1993.1174  0.84
1993 Mehrabian M, Gitt MA, Sparkes RS, Leffler H, Barondes SH, Lusis AJ. Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13. Genomics. 15: 418-20. PMID 8449510 DOI: 10.1006/geno.1993.1078  0.84
1993 Mehrabian M, Qiao JH, Hyman R, Ruddle D, Laughton C, Lusis AJ. Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 13: 1-10. PMID 8422330  0.84
1993 Gaynor RB, Shieh BH, Klisak I, Sparkes RS, Lusis AJ. Localization of the transcription factor SP1 gene to human chromosome 12q12-->q13.2. Cytogenetics and Cell Genetics. 64: 210-2. PMID 8404040 DOI: 10.1159/000133578  0.84
1993 Xia YR, Klisak I, Sparkes RS, Oram J, Lusis AJ. Localization of the gene for high-density lipoprotein binding protein (HDLBP) to human chromosome 2q37 Genomics. 16: 524-525. PMID 8390966 DOI: 10.1006/geno.1993.1221  0.84
1993 Hedrick CC, Castellani LW, Warden CH, Puppione DL, Lusis AJ. Influence of mouse apolipoprotein A-II on plasma lipoproteine in transgenic mice Journal of Biological Chemistry. 268: 20676-20682. PMID 8376417  0.84
1993 Dueland S, Drisko J, Graf L, Machleder D, Lusis AJ, Davis RA. Effect of dietary cholesterol and taurocholate on cholesterol 7α- hydroxylase and hepatic LDL receptors in inbred mice Journal of Lipid Research. 34: 923-931. PMID 8354958  0.84
1993 Warden CH, Fisler JS, Pace MJ, Svenson KL, Lusis AJ. Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model. The Journal of Clinical Investigation. 92: 773-9. PMID 8349816 DOI: 10.1172/JCI116649  0.32
1993 Warden CH, Hedrick CC, Qiao JH, Castellani LW, Lusis AJ. Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II Science. 261: 469-472. PMID 8332912  0.84
1993 Lusis AJ, Navab M. Lipoprotein oxidation and gene expression in the artery wall. New opportunities for pharmacologic intervention in atherosclerosis Biochemical Pharmacology. 46: 2119-2126. PMID 8274144 DOI: 10.1016/0006-2952(93)90599-R  0.84
1993 Qiao JH, Welch CL, Xie PZ, Fishbein MC, Lusis AJ. Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice association with aortic fatty streak development Journal of Clinical Investigation. 92: 2386-2393. PMID 8227355  0.84
1993 Andalibi A, Liao F, Imes S, Fogelman AM, Lusis AJ. Oxidized lipoproteins influence gene expression by causing oxidative stress and activating the transcription factor NF-κB Biochemical Society Transactions. 21: 651-655. PMID 8224484  0.84
1993 Dowbenko D, Andalibi A, Young PE, Lusis AJ, Lasky LA. Structure and chromosomal localization of the murine gene encoding GLYCAM 1. A mucin-like endothelial ligand for L Selectin Journal of Biological Chemistry. 268: 4525-4529. PMID 7680041  0.84
1993 Lusis AJ. The mouse model for atherosclerosis Trends in Cardiovascular Medicine. 3: 135-143. DOI: 10.1016/1050-1738(93)90014-W  0.84
1992 Li C, Lusis AJ, Sparkes R, Tran SM, Gaynor R. Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein HTLF Genomics. 13: 658-664. PMID 1639393 DOI: 10.1016/0888-7543(92)90138-I  0.84
1992 Warden CH, Diep A, Taylor BA, Lusis AJ. Localization of the gene for apolipoprotein D on mouse chromosome 16. Genomics. 12: 851-2. PMID 1572665 DOI: 10.1016/0888-7543(92)90325-M  0.84
1992 Lamon-Fava S, Sastry R, Ferrari S, Rajavashisth TB, Lusis AJ, Karathanasis SK. Evolutionary distinct mechanisms regulate apolipoprotein A-I gene expression: Differences between avian and mammalian apoA-I gene transcription control regions Journal of Lipid Research. 33: 831-842. PMID 1512510  0.84
1992 Ceci JD, Lusis AJ. Mouse Chromosome 8 Mammalian Genome. 3. PMID 1498427 DOI: 10.1007/BF00648426  0.84
1992 Mackman N, Imes S, Maske WH, Taylor B, Lusis AJ, Drake TA. Structure of the murine tissue factor gene: Chromosome location and conservation of regulatory elements in the promoter Arteriosclerosis, Thrombosis, and Vascular Biology. 12: 474-483. PMID 1348427  0.84
1992 Li C, Lusis AJ, Sparkes R, Nirula A, Gaynor R. Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein ILF Genomics. 13: 665-671. PMID 1339390 DOI: 10.1016/0888-7543(92)90139-J  0.84
1992 Lusis AJ, Castellani LW, Fisler JS. Fitting pieces from studies of animal models into the puzzle of atherosclerosis Current Opinion in Lipidology. 3: 143-150.  0.52
1991 Mehrabian M, Demer LL, Lusis AJ. Differential accumulation of intimal monocyte-macrophages relative to lipoproteins and lipofuscin corresponds to hemodynamic forces on cardiac valves in mice Arteriosclerosis, Thrombosis, and Vascular Biology. 11: 947-957. PMID 2065045  0.56
1991 Davis RC, Xia YR, Mohandas T, Schotz MC, Lusis AJ. Assignment of the human pancreatic colipase gene to chromosome 6p21.1 to pter. Genomics. 10: 262-5. PMID 2045105 DOI: 10.1016/0888-7543(91)90509-D  0.84
1991 Gaynor RB, Muchardt C, Diep A, Mohandas TK, Sparkes RS, Lusis AJ. Localization of the zinc finger DNA-binding protein HIV-EP1/MBP-1/PRDII-BF1 to human chromosome 6p22.3-p24 Genomics. 9: 758-761. PMID 2037300 DOI: 10.1016/0888-7543(91)90371-K  0.84
1991 Dowbenko DJ, Diep A, Taylor BA, Lusis AJ, Lasky LA. Characterization of the murine homing receptor gene reveals correspondence between protein domains and coding exons. Genomics. 9: 270-7. PMID 2004776 DOI: 10.1016/0888-7543(91)90252-A  0.84
1991 Mehrabian M, Sparkes RS, Mohandas T, Fogelman AM, Lusis AJ. Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1 Genomics. 9: 200-203. PMID 2004761 DOI: 10.1016/0888-7543(91)90239-B  0.84
1990 Boström K, Garcia Z, Poksay KS, Johnson DF, Lusis AJ, Innerarity TL. Apolipoprotein B mRNA editing: Direct determination of the edited base and occurrence in non-apolipoprotein B-producing cell lines Journal of Biological Chemistry. 265: 22446-22452. PMID 2266136  0.84
1990 Lusis AJ, Rajavashisth TB, Klisak I, Heinzmann C, Mohandas T, Sparkes RS. Mapping of the gene for CNBP, a finger protein, to human chromosome 3q13.3-q24 Genomics. 8: 411-414. PMID 2249857 DOI: 10.1016/0888-7543(90)90303-C  0.84
1990 Johnson LK, Frank S, Vades P, Pruzanski W, Lusis AJ, Seilhamer JJ. Localization and evolution of two human phospholipase A2 genes and two related genetic elements Advances in Experimental Medicine and Biology. 275: 17-34. PMID 2239445  0.84
1990 Johnson DF, Nierlich DP, Lusis AJ. Use of the lac repressor in constructing sequencial deletions and a new sequencing vector Gene. 94: 9-14. PMID 2172094 DOI: 10.1016/0378-1119(90)90461-Y  0.84
1990 Mehrabian M, Peter JB, Barnard RJ, Lusis AJ. Dietary regulation of fibrinolytic factors. Atherosclerosis. 84: 25-32. PMID 2147372 DOI: 10.1016/0021-9150(90)90004-3  0.84
1990 Doolittle MH, LeBoeuf RC, Warden CH, Bee LM, Lusis AJ. A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition Journal of Biological Chemistry. 265: 16380-16388. PMID 2118905  0.84
1990 LeBoeuf RC, Doolittle MH, Montcalm A, Martin DC, Reue K, Lusis AJ. Phenotypic characterization of the Ath-1 gene controlling high density lipoprotein levels and susceptibility to atherosclerosis. Journal of Lipid Research. 31: 91-101. PMID 2107272  0.84
1990 Reue KL, Warden CH, Lusis AJ. Animal models for genetic lipoprotein disorders Current Opinion in Lipidology. 1: 143-150.  0.84
1989 Williams SC, Grant SG, Reue K, Carrasquillo B, Lusis AJ, Kinniburgh AJ. cis-Acting determinants of basal and lipid-regulated apolipoprotein A-IV expression in mice Journal of Biological Chemistry. 264: 19009-19016. PMID 2808406  0.84
1989 Frank SL, Klisak I, Sparkes RS, Lusis AJ. A gene homologous to plasminogen located on human chromosome 2q11-p11 Genomics. 4: 449-451. PMID 2714803 DOI: 10.1016/0888-7543(89)90356-X  0.84
1989 Yew PR, Rajavashisth TB, Forrester J, Barath P, Lusis AJ. NIH3T3 transforming gene not a general feature of atherosclerotic plaque DNA. (atherosclerosis/oncogene/NIH3T3 transfection assay) Biochemical and Biophysical Research Communications. 165: 1067-1071. PMID 2610681 DOI: 10.1016/0006-291X(89)92710-1  0.84
1989 Frank SL, Taylor BA, Lusis AJ. Linkage of the mouse LDL receptor gene on chromosome 9. Genomics. 5: 646-8. PMID 2575592 DOI: 10.1016/0888-7543(89)90037-2  0.84
1989 Heinzmann C, Rajavashisth T, Rotter J, Lusis AJ. Kpnl RFLP for the human CSF-1 gene Nucleic Acids Research. 17: 6425. PMID 2570404 DOI: 10.1093/nar/17.15.6425  0.84
1989 Rajavashisth TB, Taylor AK, Andalibi A, Svenson KL, Lusis AJ. Identification of a zinc finger protein that binds to the sterol regulatory element Science. 245: 640-643. PMID 2562787  0.84
1988 Lusis AJ. Genetic factors affecting blood lipoproteins: the candidate gene approach Journal of Lipid Research. 29: 397-429. PMID 3292686  0.84
1988 Holm C, Kirchgessner TG, Svenson KL, Lusis AJ, Belfrage P, Schotz MC. Nucleotide sequence of rat adipose hormone sensitive lipase cDNA Nucleic Acids Research. 16: 9879. PMID 3186461 DOI: 10.1093/nar/16.20.9879  0.84
1988 Heinzmann C, Ladias J, Antonarakis S, Diep A, Schotz M, Lusis AJ. Two polymorphisms for the human hepatic lipase (HL) gene Nucleic Acids Research. 16: 4739. PMID 2454457 DOI: 10.1093/nar/16.10.4739  0.84
1987 Wion KL, Kirchgessner TG, Lusis AJ, Schotz MC, Lawn RM. Human lipoprotein lipase complementary DNA sequence Science. 235: 1638-1641. PMID 3823907 DOI: 10.1126/science.3823907  0.84
1987 Kirchgessner TG, Svenson KL, Lusis AJ, Schotz MC. The sequence of cDNA encoding lipoprotein lipase. A member of a lipase gene family Journal of Biological Chemistry. 262: 8463-8466. PMID 3597382  0.84
1987 Paigen B, Mitchell D, Reue K, Morrow A, Lusis AJ, LeBoeuf RC. Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice Proceedings of the National Academy of Sciences of the United States of America. 84: 3763-3767. PMID 3473481 DOI: 10.1073/pnas.84.11.3763  0.84
1987 Lusis AJ, Taylor BA, Quon D, Zollman S, LeBoeuf RC. Genetic factors controlling structure and expression of apolipoproteins B and E in mice. The Journal of Biological Chemistry. 262: 7594-604. PMID 3034900  0.84
1987 Heinzmann C, Ladias J, Antonarakis S, Kirchgessner T, Schotz M, Lusis AJ. RFLP for the human lipoprotein lipase (LPL) gene: HindIII Nucleic Acids Research. 15: 6763. PMID 2888089 DOI: 10.1093/nar/15.16.6763  0.84
1986 Williams SC, Bruckheimer SM, Lusis AJ, LeBoeuf RC, Kinniburgh AJ. Mouse apolipoprotein A-IV gene: nucleotide sequence and induction by a high-lipid diet Molecular and Cellular Biology. 6: 3807-3814. PMID 3796595  0.84
1986 Lusis AJ, LeBoeuf RC. Genetic control of plasma lipid transport: Mouse model Methods in Enzymology. 877-894. PMID 3724533  0.84
1986 Mohandas T, Heinzmann C, Sparkes RS, Wasmuth J, Edwards P, Lusis AJ. Assignment of human 3-hydroxy-3-methylglutaryl coenzyme A reductase gene to q13 → q23 region of chromosome 5 Somatic Cell and Molecular Genetics. 12: 89-94. PMID 3456176 DOI: 10.1007/BF01560731  0.84
1985 Lazar GS, Quon DH, Lusis AJ. A gene-controlling response of bone marrow progenitor cells to granulocyte-macrophage colony stimulating factors Journal of Cellular Physiology. 124: 293-298. PMID 3876341  0.84
1985 Rajavashisth TB, Kaptein JS, Reue KL, Lusis AJ. Evolution of apolipoprotein E: Mouse sequence and evidence for an 11-nucleotide ancestral unit Proceedings of the National Academy of Sciences of the United States of America. 82: 8085-8089. PMID 3865219  0.84
1985 Reue K, Lusis AJ, Paigen B, LeBoeuf RC. Genetic variation in high density lipoproteins (HDL) and susceptibility to atherosclerosis in the mouse Federation Proceedings. 44.  0.84
1984 Lusis AJ, Reue K, Metza L. Regulation of apolipoprotein E gene expression in the mouse Federation Proceedings. 43.  0.84
1983 LeBoeuf RC, Puppione DL, Schumaker VN, Lusis AJ. Genetic control of lipid transport in mice. I. Structural properties and polymorphisms of plasma lipoproteins. The Journal of Biological Chemistry. 258: 5063-70. PMID 6833293  0.84
1983 Lusis AJ. [44] Preparation of microsomal β-glucuronidase and its membrane anchor protein, egasyn Methods in Enzymology. 96: 557-569. PMID 6656645 DOI: 10.1016/S0076-6879(83)96048-2  0.84
1983 Lusis AJ, Chapman VM, Wangenstein RW, Paigen K. Trans-acting temporal locus within the beta-glucuronidase gene complex. Proceedings of the National Academy of Sciences of the United States of America. 80: 4398-402. PMID 6576346  0.84
1983 O'Donnell KA, Lusis AJ. Genetic evidence that the multiple apolipoprotein A-1 isoforms are encoded by a common structural gene Biochemical and Biophysical Research Communications. 114: 275-281. PMID 6411081 DOI: 10.1016/0006-291X(83)91624-8  0.84
1983 Lusis AJ, Taylor BA, Wangenstein RW, LeBoeuf RC. Genetic control of lipid transport in mice. II. Genes controlling structure of high density lipoproteins. The Journal of Biological Chemistry. 258: 5071-8. PMID 6403543  0.84
1982 Weisbart RH, Lusis AJ, Kacena A, Spolter L, Eggena P, Golde DW. Neutrophil migration inhibition factor from T lymphocytes (NIF-T): Partial purification by antibody affinity chromatography and further characterization Clinical Immunology and Immunopathology. 22: 408-418. PMID 7049465 DOI: 10.1016/0090-1229(82)90058-7  0.84
1982 Lusis AJ, Golde DW, Quon DH, Lasky LA. Translation of mRNA for human granulocyte-macrophage colony stimulating factor Nature. 298: 75-77. PMID 6979717 DOI: 10.1038/298075a0  0.84
1982 Gauwerky CE, Lusis AJ, Golde DW. Human leukemia cell line K562 responds to erythroid-potentiating activity Blood. 59: 300-305. PMID 6976809  0.84
1982 Weisbart RH, Lusis AJ, Chan G, Billing R, Ashman RF, Golde DW. Neutrophil migration inhibition factor from T lymphocytes (NIF-T): selective removal of biologic activity by human peripheral blood neutrophils, myelocytic leukemia cells, and differentiated HL-60 cells. Journal of Immunology (Baltimore, Md. : 1950). 128: 457-62. PMID 6976379  0.84
1981 Fauser AA, Messner HA, Lusis AJ, Golde DW. Stimulatory activity for human pluripotent hemopoietic progenitors produced by a human T-lymphocyte cell line Stem Cells. 1: 73-80. PMID 6983150  0.84
1981 Lusis AJ, Quon DH, Golde DW. Purification and characterization of a human T-lymphocyte-derived granulocyte-macrophage colony-stimulating factor Blood. 57: 13-21. PMID 6969609  0.84
1980 Lusis AJ, Chapman VM, Herbstman C, Paigen K. Quantitation of cis versus trans regulation of mouse beta-glucuronidase. Action of alleles of the Gus-r locus determining androgen inducibility. The Journal of Biological Chemistry. 255: 8959-62. PMID 7410401  0.84
1980 Herschman HR, Lusis AJ, Groopman JE. Growth factors. Annals of Internal Medicine. 92: 650-62. PMID 6992674  0.84
1980 Golde DW, Bersch N, Quan G, Lusis AJ. Production of erythroid-potentiating activity by a human T-lymphoblast cell line Proceedings of the National Academy of Sciences of the United States of America. 77: 593-596. PMID 6987658  0.84
1980 Gauwerky CE, Lusis AJ, Golde DW. Erythroid-potentiating activity: Characterization and target cells Experimental Hematology. 8: 117-127. PMID 6984393  0.84
1980 Koeffler HP, Billing R, Lusis AJ, Sparkes R, Golde DW. An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1) Blood. 56: 265-273. PMID 6967340  0.84
1980 Hjorth JP, Lusis AJ, Nielsen JT. Multiple structural genes for mouse amylase. Biochemical Genetics. 18: 281-302. PMID 6160849 DOI: 10.1007/BF00484242  0.84
1980 Lusis AJ, Koeffler HP. Action of granulocyte-macrophage colony-stimulating factors: Studies using a human leukemia cell line Proceedings of the National Academy of Sciences of the United States of America. 77: 5346-5350. PMID 6159645  0.84
1980 Fitchen JH, Ferrone S, Lusis AJ, Cline MJ. Cytotoxicity of anti-beta 2-microglobulin xenoantisera to human and murine myeloid progenitor cells and lack of cross-reactivity with colony-stimulating activity. Journal of Immunology (Baltimore, Md. : 1950). 124: 2906-8. PMID 6154742  0.84
1978 Lusis AJ, Paigen K. The large scale isolation of mouse β-glucuronidase and comparison of allozymes Journal of Biological Chemistry. 253: 7336-7345. PMID 701256  0.84
1978 Lusis AJ, West JD. X linked and autosomal genes controlling mouse α galactosidase expression Genetics. 88: 327-342. PMID 205481  0.84
1978 Berger FG, Lusis AJ. Relationship between genetic variation in thermal stability and electrophoretic mobility of mouse β-galactosidase Biochemical Genetics. 16: 1007-1014. PMID 105715 DOI: 10.1007/BF00483750  0.84
1977 Lusis AJ, Paigen K. Relationships between levels of membrane bound glucuronidase and the associated protein egasyn in mouse tissues Journal of Cell Biology. 73: 728-735. PMID 873997  0.84
1977 Lusis AJ, Breen GA, Paigen K. Nongenetic heterogeneity of mouse beta-galactosidase. The Journal of Biological Chemistry. 252: 4613-8. PMID 873909  0.84
1977 Lusis AJ, Tomino S, Paigen K. Inheritance in mice of the membrane anchor protein egasyn: The Eg locus determines egasyn levels Biochemical Genetics. 15: 115-122. PMID 849245 DOI: 10.1007/BF00484554  0.84
1977 Breen GA, Lusis AJ, Paigen K. Linkage of genetic determinants for mouse beta-galactosidase electrophoresis and activity. Genetics. 85: 73-84. PMID 838272  0.84
1976 Owerbach D, Lusis AJ. Phenobarbital induction of egasyn: Availability of egasyn in vivo determines glucuronidase binding to membrane Biochemical and Biophysical Research Communications. 69: 628-634. PMID 1267808 DOI: 10.1016/0006-291X(76)90922-0  0.84
1976 Lusis AJ, West JD. X-linked inheritance of a structural gene for α-galactosidease in Mus musculus Biochemical Genetics. 14: 849-855. PMID 1008807 DOI: 10.1007/BF00485346  0.84
1976 Lusis AJ, Tomino S, Paigen K. Isolation, characterization, and radioimmunoassy of murine egasyn, a protein stabilizing glucuronidase membrane binding Journal of Biological Chemistry. 251: 7753-7760. PMID 826534  0.84
1976 Lusis AJ, Paigen K. Properties of mouse α-galactosidase Bba - General Subjects. 437: 487-497. PMID 8104 DOI: 10.1016/0304-4165(76)90017-9  0.84
1975 Lusis AJ, Paigen K. Genetic determination of the α-galactosidase developmental program in mice Cell. 6: 371-378. PMID 212204 DOI: 10.1016/0092-8674(75)90186-5  0.84
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