Andrew Pekosz - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Microbiology Biology

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Grantham ML, McCown MF, Pekosz A. The Influenza A Virus M2 Protein -Complementation System Offers a Set of Tools for the Undergraduate Virology Laboratory. Journal of Microbiology & Biology Education. 20. PMID 31160927 DOI: 10.1128/jmbe.v20i1.1667  0.8
2017 Liu H, Grantham ML, Pekosz A. Mutations in the Influenza A virus M1 protein enhance virus budding to complement lethal mutations in the M2 cytoplasmic tail. Journal of Virology. PMID 29046451 DOI: 10.1128/JVI.00858-17  0.56
2015 Fischer WA, King LS, Lane AP, Pekosz A. Restricted replication of the live attenuated influenza A virus vaccine during infection of primary differentiated human nasal epithelial cells. Vaccine. 33: 4495-504. PMID 26196325 DOI: 10.1016/j.vaccine.2015.07.023  1
2015 Sussan TE, Gajghate S, Thimmulappa RK, Ma J, Kim JH, Sudini K, Consolini N, Cormier SA, Lomnicki S, Hasan F, Pekosz A, Biswal S. Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model. Plos One. 10: e0116861. PMID 25651083 DOI: 10.1371/journal.pone.0116861  1
2015 Ketscher L, Hannß R, Morales DJ, Basters A, Guerra S, Goldmann T, Hausmann A, Prinz M, Naumann R, Pekosz A, Utermöhlen O, Lenschow DJ, Knobeloch KP. Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance. Proceedings of the National Academy of Sciences of the United States of America. 112: 1577-82. PMID 25605921 DOI: 10.1073/pnas.1412881112  1
2014 Espitia CM, Saldarriaga OA, Travi BL, Osorio EY, Hernandez A, Band M, Patel MJ, Medina AA, Cappello M, Pekosz A, Melby PC. Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes. Bmc Immunology. 15: 38. PMID 25424735 DOI: 10.1186/s12865-014-0038-z  1
2014 Klein SL, Pekosz A. Sex-based biology and the rational design of influenza vaccination strategies. The Journal of Infectious Diseases. 209: S114-9. PMID 24966191 DOI: 10.1093/infdis/jiu066  1
2014 Lalime EN, Pekosz A. The R35 residue of the influenza A virus NS1 protein has minimal effects on nuclear localization but alters virus replication through disrupting protein dimerization. Virology. 458: 33-42. PMID 24928037 DOI: 10.1016/j.virol.2014.04.012  1
2014 Klein EY, Serohijos AW, Choi JM, Shakhnovich EI, Pekosz A. Influenza A H1N1 pandemic strain evolution--divergence and the potential for antigenic drift variants. Plos One. 9: e93632. PMID 24699432 DOI: 10.1371/journal.pone.0093632  1
2014 Keller B, Labrique A, Jain KM, Pekosz A, Levine O. Mind the gap: social media engagement by public health researchers. Journal of Medical Internet Research. 16: e8. PMID 24425670 DOI: 10.2196/jmir.2982  1
2013 Deal C, Pekosz A, Ketner G. Prospects for oral replicating adenovirus-vectored vaccines. Vaccine. 31: 3236-43. PMID 23707160 DOI: 10.1016/j.vaccine.2013.05.016  1
2013 Zeng H, Goldsmith CS, Maines TR, Belser JA, Gustin KM, Pekosz A, Zaki SR, Katz JM, Tumpey TM. Tropism and infectivity of influenza virus, including highly pathogenic avian H5N1 virus, in ferret tracheal differentiated primary epithelial cell cultures. Journal of Virology. 87: 2597-607. PMID 23255802 DOI: 10.1128/JVI.02885-12  1
2012 Stewart SM, Pekosz A. The influenza C virus CM2 protein can alter intracellular pH, and its transmembrane domain can substitute for that of the influenza A virus M2 protein and support infectious virus production. Journal of Virology. 86: 1277-81. PMID 21917958 DOI: 10.1128/JVI.05681-11  1
2011 Lorenzo ME, Hodgson A, Robinson DP, Kaplan JB, Pekosz A, Klein SL. Antibody responses and cross protection against lethal influenza A viruses differ between the sexes in C57BL/6 mice. Vaccine. 29: 9246-55. PMID 21983155 DOI: 10.1016/j.vaccine.2011.09.110  1
2011 Stewart SM, Pekosz A. Mutations in the membrane-proximal region of the influenza A virus M2 protein cytoplasmic tail have modest effects on virus replication. Journal of Virology. 85: 12179-87. PMID 21917980 DOI: 10.1128/JVI.05970-11  1
2011 Song JM, Wang BZ, Park KM, Van Rooijen N, Quan FS, Kim MC, Jin HT, Pekosz A, Compans RW, Kang SM. Influenza virus-like particles containing M2 induce broadly cross protective immunity. Plos One. 6: e14538. PMID 21267073 DOI: 10.1371/journal.pone.0014538  1
2011 Leibler JH, Silbergeld EK, Pekosz A, Gray GC. No evidence of infection with avian influenza viruses among US poultry workers in the Delmarva Peninsula, Maryland and Virginia, USA. Journal of Agromedicine. 16: 52-7. PMID 21213164 DOI: 10.1080/1059924X.2011.533612  1
2010 Klein SL, Passaretti C, Anker M, Olukoya P, Pekosz A. The impact of sex, gender and pregnancy on 2009 H1N1 disease. Biology of Sex Differences. 1: 5. PMID 21208468 DOI: 10.1186/2042-6410-1-5  1
2010 Ameiss K, Ashraf S, Kong W, Pekosz A, Wu WH, Milich D, Billaud JN, Curtiss R. Delivery of woodchuck hepatitis virus-like particle presented influenza M2e by recombinant attenuated Salmonella displaying a delayed lysis phenotype. Vaccine. 28: 6704-13. PMID 20691653 DOI: 10.1016/j.vaccine.2010.07.083  1
2010 Stewart SM, Wu WH, Lalime EN, Pekosz A. The cholesterol recognition/interaction amino acid consensus motif of the influenza A virus M2 protein is not required for virus replication but contributes to virulence. Virology. 405: 530-8. PMID 20655564 DOI: 10.1016/j.virol.2010.06.035  1
2010 Grandea AG, Olsen OA, Cox TC, Renshaw M, Hammond PW, Chan-Hui PY, Mitcham JL, Cieplak W, Stewart SM, Grantham ML, Pekosz A, Kiso M, Shinya K, Hatta M, Kawaoka Y, et al. Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses. Proceedings of the National Academy of Sciences of the United States of America. 107: 12658-63. PMID 20615945 DOI: 10.1073/pnas.0911806107  1
2010 Grantham ML, Stewart SM, Lalime EN, Pekosz A. Tyrosines in the influenza A virus M2 protein cytoplasmic tail are critical for production of infectious virus particles. Journal of Virology. 84: 8765-76. PMID 20573832 DOI: 10.1128/JVI.00853-10  1
2010 Klein SL, Jedlicka A, Pekosz A. The Xs and Y of immune responses to viral vaccines. The Lancet. Infectious Diseases. 10: 338-49. PMID 20417416 DOI: 10.1016/S1473-3099(10)70049-9  1
2010 Au RY, Jedlicka AE, Li W, Pekosz A, Klein SL. Seoul virus suppresses NF-kappaB-mediated inflammatory responses of antigen presenting cells from Norway rats. Virology. 400: 115-27. PMID 20170933 DOI: 10.1016/j.virol.2010.01.027  1
2010 Schaecher SR, Pekosz A. SARS coronavirus accessory gene expression and function Molecular Biology of the Sars-Coronavirus. 153-166. DOI: 10.1007/978-3-642-03683-5_10  1
2009 Li Y, Larrimer A, Curtiss T, Kim J, Jones A, Baird-Tomlinson H, Pekosz A, Olivo PD. Influenza virus assays based on virus-inducible reporter cell lines. Influenza and Other Respiratory Viruses. 3: 241-51. PMID 21462401 DOI: 10.1111/j.1750-2659.2009.00095.x  1
2009 Grantham ML, Wu WH, Lalime EN, Lorenzo ME, Klein SL, Pekosz A. Palmitoylation of the influenza A virus M2 protein is not required for virus replication in vitro but contributes to virus virulence. Journal of Virology. 83: 8655-61. PMID 19553312 DOI: 10.1128/JVI.01129-09  1
2009 Pekosz A, Newby C, Bose PS, Lutz A. Sialic acid recognition is a key determinant of influenza A virus tropism in murine trachea epithelial cell cultures. Virology. 386: 61-7. PMID 19195676 DOI: 10.1016/j.virol.2009.01.005  1
2008 Rowe RK, Suszko JW, Pekosz A. Roles for the recycling endosome, Rab8, and Rab11 in hantavirus release from epithelial cells. Virology. 382: 239-49. PMID 18951604 DOI: 10.1016/j.virol.2008.09.021  1
2008 Schaecher SR, Stabenow J, Oberle C, Schriewer J, Buller RM, Sagartz JE, Pekosz A. An immunosuppressed Syrian golden hamster model for SARS-CoV infection. Virology. 380: 312-21. PMID 18760437 DOI: 10.1016/j.virol.2008.07.026  1
2008 Schaecher SR, Diamond MS, Pekosz A. The transmembrane domain of the severe acute respiratory syndrome coronavirus ORF7b protein is necessary and sufficient for its retention in the Golgi complex. Journal of Virology. 82: 9477-91. PMID 18632859 DOI: 10.1128/JVI.00784-08  1
2008 Pekosz A, Glass GE. Emerging viral diseases. Maryland Medicine : Mm : a Publication of Medchi, the Maryland State Medical Society. 9: 11, 13-6. PMID 18491811  1
2008 Wu WH, Pekosz A. Extending the cytoplasmic tail of the influenza a virus M2 protein leads to reduced virus replication in vivo but not in vitro. Journal of Virology. 82: 1059-63. PMID 17989186 DOI: 10.1128/JVI.01499-07  1
2007 Schaecher SR, Touchette E, Schriewer J, Buller RM, Pekosz A. Severe acute respiratory syndrome coronavirus gene 7 products contribute to virus-induced apoptosis. Journal of Virology. 81: 11054-68. PMID 17686858 DOI: 10.1128/JVI.01266-07  1
2007 Newby CM, Sabin L, Pekosz A. The RNA binding domain of influenza A virus NS1 protein affects secretion of tumor necrosis factor alpha, interleukin-6, and interferon in primary murine tracheal epithelial cells. Journal of Virology. 81: 9469-80. PMID 17596305 DOI: 10.1128/JVI.00989-07  1
2007 Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A, Levine B, Schmidt RE, García-Sastre A, Leib DA, Pekosz A, Knobeloch KP, Horak I, Virgin HW. IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proceedings of the National Academy of Sciences of the United States of America. 104: 1371-6. PMID 17227866 DOI: 10.1073/pnas.0607038104  1
2007 Schaecher SR, Mackenzie JM, Pekosz A. The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles. Journal of Virology. 81: 718-31. PMID 17079322 DOI: 10.1128/JVI.01691-06  1
2006 Fang Y, Pekosz A, Haynes L, Nelson EA, Rowland RR. Production and characterization of monoclonal antibodies against the nucleocapsid protein of SARS-CoV. Advances in Experimental Medicine and Biology. 581: 153-6. PMID 17037523 DOI: 10.1007/978-0-387-33012-9_27  1
2006 Pekosz A, Schaecher SR, Diamond MS, Fremont DH, Sims AC, Baric RS. Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b. Advances in Experimental Medicine and Biology. 581: 115-20. PMID 17037516 DOI: 10.1007/978-0-387-33012-9_20  1
2006 Newby CM, Rowe RK, Pekosz A. Influenza A virus infection of primary differentiated airway epithelial cell cultures derived from Syrian golden hamsters. Virology. 354: 80-90. PMID 16876846 DOI: 10.1016/j.virol.2006.06.024  1
2006 McCown MF, Pekosz A. Distinct domains of the influenza a virus M2 protein cytoplasmic tail mediate binding to the M1 protein and facilitate infectious virus production. Journal of Virology. 80: 8178-89. PMID 16873274 DOI: 10.1128/JVI.00627-06  1
2006 Ibricevic A, Pekosz A, Walter MJ, Newby C, Battaile JT, Brown EG, Holtzman MJ, Brody SL. Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells. Journal of Virology. 80: 7469-80. PMID 16840327 DOI: 10.1128/JVI.02677-05  1
2006 Rowe RK, Pekosz A. Bidirectional virus secretion and nonciliated cell tropism following Andes virus infection of primary airway epithelial cell cultures. Journal of Virology. 80: 1087-97. PMID 16414986 DOI: 10.1128/JVI.80.3.1087-1097.2006  1
2005 Rowland RR, Chauhan V, Fang Y, Pekosz A, Kerrigan M, Burton MD. Intracellular localization of the severe acute respiratory syndrome coronavirus nucleocapsid protein: absence of nucleolar accumulation during infection and after expression as a recombinant protein in vero cells. Journal of Virology. 79: 11507-12. PMID 16103202 DOI: 10.1128/JVI.79.17.11507-11512.2005  1
2005 Luker KE, Hutchens M, Schultz T, Pekosz A, Luker GD. Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread. Virology. 341: 284-300. PMID 16095645 DOI: 10.1016/j.virol.2005.06.049  1
2005 Lutz A, Dyall J, Olivo PD, Pekosz A. Virus-inducible reporter genes as a tool for detecting and quantifying influenza A virus replication. Journal of Virological Methods. 126: 13-20. PMID 15847914 DOI: 10.1016/j.jviromet.2005.01.016  1
2005 McCown MF, Pekosz A. The influenza A virus M2 cytoplasmic tail is required for infectious virus production and efficient genome packaging. Journal of Virology. 79: 3595-605. PMID 15731254 DOI: 10.1128/JVI.79.6.3595-3605.2005  1
2005 Nelson CA, Pekosz A, Lee CA, Diamond MS, Fremont DH. Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein. Structure (London, England : 1993). 13: 75-85. PMID 15642263 DOI: 10.1016/j.str.2004.10.010  1
2005 Barchet W, Krug A, Cella M, Newby C, Fischer JA, Dzionek A, Pekosz A, Colonna M. Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways. European Journal of Immunology. 35: 236-42. PMID 15593126 DOI: 10.1002/eji.200425583  1
2004 Rowe RK, Brody SL, Pekosz A. Differentiated cultures of primary hamster tracheal airway epithelial cells. In Vitro Cellular & Developmental Biology. Animal. 40: 303-11. PMID 15780007 DOI: 10.1290/0408056.1  1
2003 McCown M, Diamond MS, Pekosz A. The utility of siRNA transcripts produced by RNA polymerase i in down regulating viral gene expression and replication of negative- and positive-strand RNA viruses. Virology. 313: 514-24. PMID 12954218 DOI: 10.1016/S0042-6822(03)00341-6  1
2003 Krug A, Veeraswamy R, Pekosz A, Kanagawa O, Unanue ER, Colonna M, Cella M. Interferon-producing cells fail to induce proliferation of naive T cells but can promote expansion and T helper 1 differentiation of antigen-experienced unpolarized T cells. The Journal of Experimental Medicine. 197: 899-906. PMID 12668648 DOI: 10.1084/jem.20021091  1
2002 Takeda M, Pekosz A, Shuck K, Pinto LH, Lamb RA. Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture. Journal of Virology. 76: 1391-9. PMID 11773413  1
2000 Pekosz A, Lamb RA. Identification of a membrane targeting and degradation signal in the p42 protein of influenza C virus. Journal of Virology. 74: 10480-8. PMID 11044092 DOI: 10.1128/JVI.74.22.10480-10488.2000  1
2000 Mould JA, Drury JE, Frings SM, Kaupp UB, Pekosz A, Lamb RA, Pinto LH. Permeation and activation of the M2 ion channel of influenza A virus. The Journal of Biological Chemistry. 275: 31038-50. PMID 10913133 DOI: 10.1074/jbc.M003663200  1
2000 Zhang J, Pekosz A, Lamb RA. Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins. Journal of Virology. 74: 4634-44. PMID 10775599 DOI: 10.1128/JVI.74.10.4634-4644.2000  1
2000 Zhang J, Leser GP, Pekosz A, Lamb RA. The cytoplasmic tails of the influenza virus spike glycoproteins are required for normal genome packaging. Virology. 269: 325-34. PMID 10753711 DOI: 10.1006/viro.2000.0228  1
2000 Mould JA, Li HC, Dudlak CS, Lear JD, Pekosz A, Lamb RA, Pinto LH. Mechanism for proton conduction of the M(2) ion channel of influenza A virus. The Journal of Biological Chemistry. 275: 8592-9. PMID 10722698 DOI: 10.1074/jbc.275.12.8592  1
1999 Pekosz A, Lamb RA. Cell surface expression of biologically active influenza C virus HEF glycoprotein expressed from cDNA. Journal of Virology. 73: 8808-12. PMID 10482635  1
1999 Pekosz A, He B, Lamb RA. Reverse genetics of negative-strand RNA viruses: closing the circle. Proceedings of the National Academy of Sciences of the United States of America. 96: 8804-6. PMID 10430844 DOI: 10.1073/pnas.96.16.8804  1
1998 Pekosz A, Lamb RA. Influenza C virus CM2 integral membrane glycoprotein is produced from a polypeptide precursor by cleavage of an internal signal sequence. Proceedings of the National Academy of Sciences of the United States of America. 95: 13233-8. PMID 9789071 DOI: 10.1073/pnas.95.22.13233  1
1997 Pekosz A, Lamb RA. The CM2 protein of influenza C virus is an oligomeric integral membrane glycoprotein structurally analogous to influenza A virus M2 and influenza B virus NB proteins. Virology. 237: 439-51. PMID 9356355 DOI: 10.1006/viro.1997.8788  1
1997 Tatarowicz WA, Martin CE, Pekosz AS, Madden SL, Rauscher FJ, Chiang SY, Beerman TA, Fraser NW. Repression of the HSV-1 latency-associated transcript (LAT) promoter by the early growth response (EGR) proteins: involvement of a binding site immediately downstream of the TATA box. Journal of Neurovirology. 3: 212-24. PMID 9200069  1
1996 Pekosz A, González-Scarano F. The extracellular domain of La Crosse virus G1 forms oligomers and undergoes pH-dependent conformational changes Virology. 225: 243-247. PMID 8918555 DOI: 10.1006/viro.1996.0596  1
1996 Pekosz A, Phillips J, Pleasure D, Merry D, Gonzalez-Scarano F. Induction of apoptosis by La Crosse virus infection and role of neuronal differentiation and human bcl-2 expression in its prevention Journal of Virology. 70: 5329-5335. PMID 8764043  1
1995 Pekosz A, Griot C, Nathanson N, Gonzalez-Scarano F. Tropism of bunyaviruses: evidence for a G1 glycoprotein-mediated entry pathway common to the California serogroup. Virology. 214: 339-48. PMID 8553534 DOI: 10.1006/viro.1995.0043  1
1995 Pekosz A, Griot C, Stillmock K, Nathanson N, Gonzalez-Scarano F. Protection from La Crosse virus encephalitis with recombinant glycoproteins: role of neutralizing anti-G1 antibodies. Journal of Virology. 69: 3475-81. PMID 7745694  1
1994 Griot C, Pekosz A, Davidson R, Stillmock K, Hoek M, Lukac D, Schmeidler D, Cobbinah I, Gonzalez-Scarano F, Nathanson N. Replication in cultured C2C12 muscle cells correlates with the neuroinvasiveness of California serogroup bunyaviruses. Virology. 201: 399-403. PMID 8184551 DOI: 10.1006/viro.1994.1308  1
1993 Griot C, Pekosz A, Lukac D, Scherer SS, Stillmock K, Schmeidler D, Endres MJ, Gonzalez-Scarano F, Nathanson N. Polygenic control of neuroinvasiveness in California serogroup bunyaviruses. Journal of Virology. 67: 3861-7. PMID 8510208  1
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