Glen N. Barber - Publications

Affiliations: 
University of Miami, Coral Gables, FL 
Area:
Immunology, Microbiology Biology

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, Barber GN, Arai H, Taguchi T. Activation of STING requires palmitoylation at the Golgi. Nature Communications. 7: 11932. PMID 27324217 DOI: 10.1038/ncomms11932  1
2016 Castro I, Giret TM, Magnani DM, Maxwell HS, Umland O, Perry JK, Pecotte JK, Brasky KM, Barber GN, Desrosiers RC, Watkins DI. Cellular Immune Responses Against the Simian T-Lymphotropic Virus type 1 (STLV-1) Target Tax in Infected Baboons. Journal of Virology. PMID 26984729 DOI: 10.1128/JVI.00281-16  1
2015 Xia T, Konno H, Ahn J, Barber GN. Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis. Cell Reports. PMID 26748708 DOI: 10.1016/j.celrep.2015.12.029  1
2015 Barber GN. STING: infection, inflammation and cancer. Nature Reviews. Immunology. 15: 760-70. PMID 26603901 DOI: 10.1038/nri3921  1
2015 Agarwal NK, Kim CH, Kunkalla K, Konno H, Tjendra Y, Kwon D, Blonska M, Kozloski GA, Moy VT, Verdun RE, Barber GN, Lossos IS, Vega F. Active IKKβ promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma. Blood. PMID 26603838 DOI: 10.1182/blood-2015-07-658781  1
2015 Betancourt D, Ramos JC, Barber GN. Retargeting Oncolytic Vesicular Stomatitis Virus to Human T-Cell Lymphotropic Virus Type 1-Associated Adult T-Cell Leukemia. Journal of Virology. 89: 11786-800. PMID 26378177 DOI: 10.1128/JVI.01356-15  1
2015 Ma Z, Jacobs SR, West JA, Stopford C, Zhang Z, Davis Z, Barber GN, Glaunsinger BA, Dittmer DP, Damania B. Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 26199418 DOI: 10.1073/pnas.1503831112  1
2015 Kobayashi H, Kobayashi CI, Nakamura-Ishizu A, Karigane D, Haeno H, Yamamoto KN, Sato T, Ohteki T, Hayakawa Y, Barber GN, Kurokawa M, Suda T, Takubo K. Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING. Cell Reports. 11: 71-84. PMID 25843711 DOI: 10.1016/j.celrep.2015.02.066  1
2015 Hyun J, Ramos JC, Toomey N, Balachandran S, Lavorgna A, Harhaj E, Barber GN. Oncogenic human T-cell lymphotropic virus type 1 tax suppression of primary innate immune signaling pathways. Journal of Virology. 89: 4880-93. PMID 25694597 DOI: 10.1128/JVI.02493-14  1
2015 Chan MP, Onji M, Fukui R, Kawane K, Shibata T, Saitoh S, Ohto U, Shimizu T, Barber GN, Miyake K. DNase II-dependent DNA digestion is required for DNA sensing by TLR9. Nature Communications. 6: 5853. PMID 25600358 DOI: 10.1038/ncomms6853  1
2015 Tesfay MZ, Ammayappan A, Federspiel MJ, Barber GN, Stojdl D, Peng KW, Russell SJ. Correction to Vesiculovirus neutralization by natural IgM and complement [Journal of Virology, 88, 11 (2014), 6148-6157] Journal of Virology. 89: 1945-1946. DOI: 10.1128/JVI.03326-14  1
2015 Ahn J, Konno H, Barber GN. Diverse roles of STING-dependent signaling on the development of cancer Oncogene. 34: 5302-5308. DOI: 10.1038/onc.2014.457  1
2014 Woo SR, Fuertes MB, Corrales L, Spranger S, Furdyna MJ, Leung MY, Duggan R, Wang Y, Barber GN, Fitzgerald KA, Alegre ML, Gajewski TF. STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. Immunity. 41: 830-42. PMID 25517615 DOI: 10.1016/J.IMMUNI.2014.12.015  1
2014 Ahn J, Barber GN. Self-DNA, STING-dependent signaling and the origins of autoinflammatory disease. Current Opinion in Immunology. 31: 121-6. PMID 25459004 DOI: 10.1016/j.coi.2014.10.009  1
2014 Konno H, Barber GN. The STING controlled cytosolic-DNA activated innate immune pathway and microbial disease. Microbes and Infection / Institut Pasteur. 16: 998-1001. PMID 25449752 DOI: 10.1016/j.micinf.2014.10.002  1
2014 Ahn J, Xia T, Konno H, Konno K, Ruiz P, Barber GN. Inflammation-driven carcinogenesis is mediated through STING. Nature Communications. 5: 5166. PMID 25300616 DOI: 10.1038/ncomms6166  1
2014 Ahn J, Ruiz P, Barber GN. Intrinsic self-DNA triggers inflammatory disease dependent on STING. Journal of Immunology (Baltimore, Md. : 1950). 193: 4634-42. PMID 25261479 DOI: 10.4049/jimmunol.1401337  1
2014 Yarbrough ML, Zhang K, Sakthivel R, Forst CV, Posner BA, Barber GN, White MA, Fontoura BM. Primate-specific miR-576-3p sets host defense signalling threshold. Nature Communications. 5: 4963. PMID 25232931 DOI: 10.1038/ncomms5963  1
2014 Lemos H, Huang L, Chandler PR, Mohamed E, Souza GR, Li L, Pacholczyk G, Barber GN, Hayakawa Y, Munn DH, Mellor AL. Activation of the STING adaptor attenuates experimental autoimmune encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 192: 5571-8. PMID 24799564 DOI: 10.4049/jimmunol.1303258  1
2014 Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T. Nucleic acid sensing by T cells initiates Th2 cell differentiation. Nature Communications. 5: 3566. PMID 24717539 DOI: 10.1038/ncomms4566  1
2014 Tesfay MZ, Ammayappan A, Federspiel MJ, Barber GN, Stojdl D, Peng KW, Russell SJ. Vesiculovirus neutralization by natural IgM and complement. Journal of Virology. 88: 6148-57. PMID 24648451 DOI: 10.1128/JVI.00074-14  1
2014 Abe T, Barber GN. Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1. Journal of Virology. 88: 5328-41. PMID 24600004 DOI: 10.1128/JVI.00037-14  1
2014 Barber GN. STING-dependent cytosolic DNA sensing pathways. Trends in Immunology. 35: 88-93. PMID 24309426 DOI: 10.1016/j.it.2013.10.010  1
2014 Aikawa H, Tamai M, Mitamura K, Itmainati F, Barber GN, Tagawa Y. Innate immunity in an in vitro murine blastocyst model using embryonic and trophoblast stem cells. Journal of Bioscience and Bioengineering. 117: 358-65. PMID 24113362 DOI: 10.1016/j.jbiosc.2013.09.001  1
2014 Rosenblatt JD, Podack ER, Barber GN, Ochoa A. Advances in Tumor Immunology and Immunotherapy Current Cancer Research. 12. DOI: 10.1007/978-1-4614-8809-5  1
2013 Ma Z, Moore R, Xu X, Barber GN. DDX24 negatively regulates cytosolic RNA-mediated innate immune signaling. Plos Pathogens. 9: e1003721. PMID 24204270 DOI: 10.1371/journal.ppat.1003721  1
2013 Konno H, Konno K, Barber GN. Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling. Cell. 155: 688-98. PMID 24119841 DOI: 10.1016/j.cell.2013.09.049  1
2013 Huang L, Li L, Lemos H, Chandler PR, Pacholczyk G, Baban B, Barber GN, Hayakawa Y, McGaha TL, Ravishankar B, Munn DH, Mellor AL. Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses. Journal of Immunology (Baltimore, Md. : 1950). 191: 3509-13. PMID 23986532 DOI: 10.4049/jimmunol.1301419  1
2013 Chin KH, Tu ZL, Su YC, Yu YJ, Chen HC, Lo YC, Chen CP, Barber GN, Chuah ML, Liang ZX, Chou SH. Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING. Acta Crystallographica. Section D, Biological Crystallography. 69: 352-66. PMID 23519410 DOI: 10.1107/S0907444912047269  1
2013 Abe T, Harashima A, Xia T, Konno H, Konno K, Morales A, Ahn J, Gutman D, Barber GN. STING recognition of cytoplasmic DNA instigates cellular defense. Molecular Cell. 50: 5-15. PMID 23478444 DOI: 10.1016/j.molcel.2013.01.039  1
2013 Kondo T, Kobayashi J, Saitoh T, Maruyama K, Ishii KJ, Barber GN, Komatsu K, Akira S, Kawai T. DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking. Proceedings of the National Academy of Sciences of the United States of America. 110: 2969-74. PMID 23388631 DOI: 10.1073/pnas.1222694110  1
2013 Tesfay MZ, Kirk AC, Hadac EM, Griesmann GE, Federspiel MJ, Barber GN, Henry SM, Peng KW, Russell SJ. PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice. Journal of Virology. 87: 3752-9. PMID 23325695 DOI: 10.1128/JVI.02832-12  1
2013 Barber GN. Cytosolic DNA-Sensing and the STING Pathway Biological Dna Sensor: the Impact of Nucleic Acids On Diseases and Vaccinology. 67-81. DOI: 10.1016/B978-0-12-404732-7.00003-4  1
2012 Ahn J, Gutman D, Saijo S, Barber GN. STING manifests self DNA-dependent inflammatory disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 19386-91. PMID 23132945 DOI: 10.1073/pnas.1215006109  1
2012 Aguirre S, Maestre AM, Pagni S, Patel JR, Savage T, Gutman D, Maringer K, Bernal-Rubio D, Shabman RS, Simon V, Rodriguez-Madoz JR, Mulder LC, Barber GN, Fernandez-Sesma A. DENV inhibits type I IFN production in infected cells by cleaving human STING. Plos Pathogens. 8: e1002934. PMID 23055924 DOI: 10.1371/journal.ppat.1002934  1
2012 Liu YP, Zeng L, Tian A, Bomkamp A, Rivera D, Gutman D, Barber GN, Olson JK, Smith JA. Endoplasmic reticulum stress regulates the innate immunity critical transcription factor IRF3. Journal of Immunology (Baltimore, Md. : 1950). 189: 4630-9. PMID 23028052 DOI: 10.4049/jimmunol.1102737  1
2012 Naik S, Nace R, Barber GN, Russell SJ. Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-Β Cancer Gene Therapy. 19: 443-450. PMID 22522623 DOI: 10.1038/cgt.2012.14  1
2012 Naik S, Nace R, Federspiel MJ, Barber GN, Peng KW, Russell SJ. Curative one-shot systemic virotherapy in murine myeloma Leukemia. 26: 1870-1878. PMID 22425894 DOI: 10.1038/leu.2012.70  1
2012 Gall A, Treuting P, Elkon KB, Loo YM, Gale M, Barber GN, Stetson DB. Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity. 36: 120-31. PMID 22284419 DOI: 10.1016/j.immuni.2011.11.018  1
2012 Ayala-Breton C, Barber GN, Russell SJ, Peng KW. Retargeting vesicular stomatitis virus using measles virus envelope glycoproteins. Human Gene Therapy. 23: 484-91. PMID 22171635 DOI: 10.1089/hum.2011.146  1
2012 Heiber JF, Barber GN. Evaluation of innate immune signaling pathways in transformed cells. Methods in Molecular Biology (Clifton, N.J.). 797: 217-38. PMID 21948479 DOI: 10.1007/978-1-61779-340-0_15  1
2011 Heiber JF, Xu XX, Barber GN. Potential of vesicular stomatitis virus as an oncolytic therapy for recurrent and drug-resistant ovarian cancer. Chinese Journal of Cancer. 30: 805-14. PMID 22059911 DOI: 10.5732/cjc.011.10205  1
2011 Barber GN. STING-dependent signaling. Nature Immunology. 12: 929-30. PMID 21934672 DOI: 10.1038/ni.2118  1
2011 Barber GN. Cytoplasmic DNA innate immune pathways. Immunological Reviews. 243: 99-108. PMID 21884170 DOI: 10.1111/j.1600-065X.2011.01051.x  1
2011 Sharma S, DeOliveira RB, Kalantari P, Parroche P, Goutagny N, Jiang Z, Chan J, Bartholomeu DC, Lauw F, Hall JP, Barber GN, Gazzinelli RT, Fitzgerald KA, Golenbock DT. Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome. Immunity. 35: 194-207. PMID 21820332 DOI: 10.1016/j.immuni.2011.05.016  1
2011 Heiber JF, Barber GN. Vesicular stomatitis virus expressing tumor suppressor p53 is a highly attenuated, potent oncolytic agent. Journal of Virology. 85: 10440-50. PMID 21813611 DOI: 10.1128/JVI.05408-11  1
2011 Elsby R, Heiber JF, Reid P, Kimball SR, Pavitt GD, Barber GN. The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus. Journal of Virology. 85: 9716-25. PMID 21795329 DOI: 10.1128/JVI.05146-11  1
2011 Wang L, Toomey NL, Diaz LA, Walker G, Ramos JC, Barber GN, Ning S. Oncogenic IRFs provide a survival advantage for Epstein-Barr virus- or human T-cell leukemia virus type 1-transformed cells through induction of BIC expression. Journal of Virology. 85: 8328-37. PMID 21680528 DOI: 10.1128/JVI.00570-11  1
2011 Pollpeter D, Komuro A, Barber GN, Horvath CM. Impaired cellular responses to cytosolic DNA or infection with Listeria monocytogenes and vaccinia virus in the absence of the murine LGP2 protein. Plos One. 6: e18842. PMID 21533147 DOI: 10.1371/journal.pone.0018842  1
2011 Ning S, Pagano JS, Barber GN. IRF7: Activation, regulation, modification and function Genes and Immunity. 12: 399-414. PMID 21490621 DOI: 10.1038/gene.2011.21  1
2011 Barber GN. Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses. Current Opinion in Immunology. 23: 10-20. PMID 21239155 DOI: 10.1016/j.coi.2010.12.015  1
2011 Ishikawa H, Barber GN. The STING pathway and regulation of innate immune signaling in response to DNA pathogens. Cellular and Molecular Life Sciences : Cmls. 68: 1157-65. PMID 21161320 DOI: 10.1007/s00018-010-0605-2  1
2011 Gualco G, Weiss LM, Barber GN, Bacchi CE. Diffuse large B-cell lymphoma involving the central nervous system. International Journal of Surgical Pathology. 19: 44-50. PMID 21087986 DOI: 10.1177/1066896910386476  1
2010 Gualco G, Klumb CE, Barber GN, Weiss LM, Bacchi CE. Pediatric lymphomas in Brazil. Clinics (SãO Paulo, Brazil). 65: 1267-77. PMID 21340214 DOI: 10.1590/S1807-59322010001200008  1
2010 Harashima A, Guettouche T, Barber GN. Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense. Genes & Development. 24: 2640-53. PMID 21123651 DOI: 10.1101/gad.1965010  1
2010 Gualco G, Weiss LM, Barber GN, Bacchi CE. T-cell leukemia 1 expression in nodal Epstein-Barr virus-negative diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma. Human Pathology. 41: 1238-44. PMID 20382409 DOI: 10.1016/j.humpath.2010.01.015  1
2010 Parvatiyar K, Barber GN, Harhaj EW. TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases. The Journal of Biological Chemistry. 285: 14999-5009. PMID 20304918 DOI: 10.1074/jbc.M110.109819  1
2010 Galivo F, Diaz RM, Wongthida P, Thompson J, Kottke T, Barber G, Melcher A, Vile R. Single-cycle viral gene expression, rather than progressive replication and oncolysis, is required for VSV therapy of B16 melanoma. Gene Therapy. 17: 158-70. PMID 20016540 DOI: 10.1038/gt.2009.161  1
2010 Capo-chichi CD, Yeasky TM, Heiber JF, Wang Y, Barber GN, Xu XX. Explicit targeting of transformed cells by VSV in ovarian epithelial tumor-bearing Wv mouse models. Gynecologic Oncology. 116: 269-75. PMID 19932656 DOI: 10.1016/j.ygyno.2009.10.086  1
2010 Galivo F, Diaz RM, Thanarajasingam U, Jevremovic D, Wongthida P, Thompson J, Kottke T, Barber GN, Melcher A, Vile RG. Interference of CD40L-mediated tumor immunotherapy by oncolytic vesicular stomatitis virus. Human Gene Therapy. 21: 439-50. PMID 19922169 DOI: 10.1089/hum.2009.143  1
2010 Jenks N, Myers R, Greiner SM, Thompson J, Mader EK, Greenslade A, Griesmann GE, Federspiel MJ, Rakela J, Borad MJ, Vile RG, Barber GN, Meier TR, Blanco MC, Carlson SK, et al. Safety studies on intrahepatic or intratumoral injection of oncolytic vesicular stomatitis virus expressing interferon-beta in rodents and nonhuman primates. Human Gene Therapy. 21: 451-62. PMID 19911974 DOI: 10.1089/hum.2009.111  1
2010 Kelly EJ, Nace R, Barber GN, Russell SJ. Attenuation of vesicular stomatitis virus encephalitis through microRNA targeting. Journal of Virology. 84: 1550-62. PMID 19906911 DOI: 10.1128/JVI.01788-09  1
2010 Saloura V, Wang LC, Fridlender ZG, Sun J, Cheng G, Kapoor V, Sterman DH, Harty RN, Okumura A, Barber GN, Vile RG, Federspiel MJ, Russell SJ, Litzky L, Albelda SM. Evaluation of an attenuated vesicular stomatitis virus vector expressing interferon-beta for use in malignant pleural mesothelioma: heterogeneity in interferon responsiveness defines potential efficacy. Human Gene Therapy. 21: 51-64. PMID 19715403 DOI: 10.1089/hum.2009.088  1
2009 Ishikawa H, Ma Z, Barber GN. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature. 461: 788-92. PMID 19776740 DOI: 10.1038/nature08476  1
2009 Willmon CL, Saloura V, Fridlender ZG, Wongthida P, Diaz RM, Thompson J, Kottke T, Federspiel M, Barber G, Albelda SM, Vile RG. Expression of IFN-beta enhances both efficacy and safety of oncolytic vesicular stomatitis virus for therapy of mesothelioma. Cancer Research. 69: 7713-20. PMID 19773437 DOI: 10.1158/0008-5472.CAN-09-1013  1
2009 Chakraborty P, Seemann J, Mishra RK, Wei JH, Weil L, Nussenzveig DR, Heiber J, Barber GN, Dasso M, Fontoura BM. Vesicular stomatitis virus inhibits mitotic progression and triggers cell death. Embo Reports. 10: 1154-60. PMID 19745842 DOI: 10.1038/embor.2009.179  1
2009 Barral PM, Sarkar D, Su ZZ, Barber GN, DeSalle R, Racaniello VR, Fisher PB. Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity. Pharmacology & Therapeutics. 124: 219-34. PMID 19615405 DOI: 10.1016/j.pharmthera.2009.06.012  1
2009 Barber GN. The NFAR's (nuclear factors associated with dsRNA): evolutionarily conserved members of the dsRNA binding protein family. Rna Biology. 6: 35-9. PMID 19106622  1
2008 Kottke T, Diaz RM, Kaluza K, Pulido J, Galivo F, Wongthida P, Thompson J, Willmon C, Barber GN, Chester J, Selby P, Strome S, Harrington K, Melcher A, Vile RG. Use of biological therapy to enhance both virotherapy and adoptive T-cell therapy for cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1910-8. PMID 18827807 DOI: 10.1038/mt.2008.212  1
2008 Ishikawa H, Barber GN. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature. 455: 674-8. PMID 18724357 DOI: 10.1038/nature07317  1
2008 Kottke T, Galivo F, Wongthida P, Diaz RM, Thompson J, Jevremovic D, Barber GN, Hall G, Chester J, Selby P, Harrington K, Melcher A, Vile RG. Treg depletion-enhanced IL-2 treatment facilitates therapy of established tumors using systemically delivered oncolytic virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1217-26. PMID 18431359 DOI: 10.1038/mt.2008.83  1
2008 Pfeifer I, Elsby R, Fernandez M, Faria PA, Nussenzveig DR, Lossos IS, Fontoura BM, Martin WD, Barber GN. NFAR-1 and -2 modulate translation and are required for efficient host defense. Proceedings of the National Academy of Sciences of the United States of America. 105: 4173-8. PMID 18337511 DOI: 10.1073/pnas.0711222105  1
2008 Hickman HD, Takeda K, Skon CN, Murray FR, Hensley SE, Loomis J, Barber GN, Bennink JR, Yewdell JW. Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes. Nature Immunology. 9: 155-65. PMID 18193049 DOI: 10.1038/ni1557  1
2008 Qiao J, Kottke T, Willmon C, Galivo F, Wongthida P, Diaz RM, Thompson J, Ryno P, Barber GN, Chester J, Selby P, Harrington K, Melcher A, Vile RG. Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy. Nature Medicine. 14: 37-44. PMID 18066076 DOI: 10.1038/nm1681  1
2008 Ishikawa H, Barber GN. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling (Nature (2008) 455, (674-678)) Nature. 456: 274. DOI: 10.1038/nature07432  1
2007 Balachandran S, Barber GN. PKR in innate immunity, cancer, and viral oncolysis. Methods in Molecular Biology (Clifton, N.J.). 383: 277-301. PMID 18217692 DOI: 10.1007/978-1-59745-335-6_18  1
2007 von Holzen U, Pataer A, Raju U, Bocangel D, Vorburger SA, Liu Y, Lu X, Roth JA, Aggarwal BB, Barber GN, Keyomarsi K, Hunt KK, Swisher SG. The double-stranded RNA-activated protein kinase mediates radiation resistance in mouse embryo fibroblasts through nuclear factor kappaB and Akt activation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6032-9. PMID 17947465 DOI: 10.1158/1078-0432.CCR-06-2932  1
2007 Sarkar D, Park ES, Barber GN, Fisher PB. Activation of double-stranded RNA dependent protein kinase, a new pathway by which human polynucleotide phosphorylase (hPNPase(old-35)) induces apoptosis. Cancer Research. 67: 7948-53. PMID 17804700 DOI: 10.1158/0008-5472.CAN-07-0872  1
2007 Andrews NP, Pack CD, Vezys V, Barber GN, Lukacher AE. Early virus-associated bystander events affect the fitness of the CD8 T cell response to persistent virus infection. Journal of Immunology (Baltimore, Md. : 1950). 178: 7267-75. PMID 17513776  1
2007 Venkataraman T, Valdes M, Elsby R, Kakuta S, Caceres G, Saijo S, Iwakura Y, Barber GN. Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses. Journal of Immunology (Baltimore, Md. : 1950). 178: 6444-55. PMID 17475874  1
2007 Greidinger EL, Zang Y, Martinez L, Jaimes K, Nassiri M, Bejarano P, Barber GN, Hoffman RW. Differential tissue targeting of autoimmunity manifestations by autoantigen-associated Y RNAs. Arthritis and Rheumatism. 56: 1589-97. PMID 17469141 DOI: 10.1002/art.22601  1
2007 Diaz RM, Galivo F, Kottke T, Wongthida P, Qiao J, Thompson J, Valdes M, Barber G, Vile RG. Oncolytic immunovirotherapy for melanoma using vesicular stomatitis virus. Cancer Research. 67: 2840-8. PMID 17363607 DOI: 10.1158/0008-5472.CAN-06-3974  1
2007 Radtke AL, Delbridge LM, Balachandran S, Barber GN, O'Riordan MX. TBK1 protects vacuolar integrity during intracellular bacterial infection. Plos Pathogens. 3: e29. PMID 17335348 DOI: 10.1371/journal.ppat.0030029  1
2007 Balachandran S, Venkataraman T, Fisher PB, Barber GN. Fas-associated death domain-containing protein-mediated antiviral innate immune signaling involves the regulation of Irf7. Journal of Immunology (Baltimore, Md. : 1950). 178: 2429-39. PMID 17277150  1
2007 Goodman AG, Smith JA, Balachandran S, Perwitasari O, Proll SC, Thomas MJ, Korth MJ, Barber GN, Schiff LA, Katze MG. The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism. Journal of Virology. 81: 2221-30. PMID 17166899 DOI: 10.1128/JVI.02151-06  1
2006 Majid AM, Ezelle H, Shah S, Barber GN. Evaluating replication-defective vesicular stomatitis virus as a vaccine vehicle. Journal of Virology. 80: 6993-7008. PMID 16809305 DOI: 10.1128/JVI.00365-06  1
2006 Lin L, Su Z, Lebedeva IV, Gupta P, Boukerche H, Rai T, Barber GN, Dent P, Sarkar D, Fisher PB. Activation of Ras/Raf protects cells from melanoma differentiation-associated gene-5-induced apoptosis. Cell Death and Differentiation. 13: 1982-93. PMID 16575407 DOI: 10.1038/sj.cdd.4401899  1
2006 Greidinger EL, Zang Y, Jaimes K, Hogenmiller S, Nassiri M, Bejarano P, Barber GN, Hoffman RW. A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen. Arthritis and Rheumatism. 54: 661-9. PMID 16453294 DOI: 10.1002/art.21566  1
2005 Barber GN. VSV-tumor selective replication and protein translation. Oncogene. 24: 7710-9. PMID 16299531 DOI: 10.1038/sj.onc.1209042  1
2005 Pataer A, Vorburger SA, Chada S, Balachandran S, Barber GN, Roth JA, Hunt KK, Swisher SG. Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 717-23. PMID 15851010 DOI: 10.1016/j.ymthe.2005.01.018  1
2005 Barber GN. The dsRNA-dependent protein kinase, PKR and cell death Cell Death and Differentiation. 12: 563-570. PMID 15846372 DOI: 10.1038/sj.cdd.4401643  1
2005 Kurokawa M, Ghosh SK, Ramos JC, Mian AM, Toomey NL, Cabral L, Whitby D, Barber GN, Dittmer DP, Harrington WJ. Azidothymidine inhibits NF-kappaB and induces Epstein-Barr virus gene expression in Burkitt lymphoma. Blood. 106: 235-40. PMID 15790788 DOI: 10.1182/blood-2004-09-3748  1
2005 Faria PA, Chakraborty P, Levay A, Barber GN, Ezelle HJ, Enninga J, Arana C, van Deursen J, Fontoura BM. VSV disrupts the Rae1/mrnp41 mRNA nuclear export pathway. Molecular Cell. 17: 93-102. PMID 15629720 DOI: 10.1016/j.molcel.2004.11.023  1
2004 Barber GN. Vesicular stomatitis virus as an oncolytic vector. Viral Immunology. 17: 516-27. PMID 15671748 DOI: 10.1089/vim.2004.17.516  1
2004 Balachandran S, Thomas E, Barber GN. A FADD-dependent innate immune mechanism in mammalian cells. Nature. 432: 401-5. PMID 15549108 DOI: 10.1038/nature03124  1
2004 Perkins DJ, Barber GN. Defects in translational regulation mediated by the alpha subunit of eukaryotic initiation factor 2 inhibit antiviral activity and facilitate the malignant transformation of human fibroblasts. Molecular and Cellular Biology. 24: 2025-40. PMID 14966282 DOI: 10.1128/MCB.24.5.2025-2040.2004  1
2004 Balachandran S, Barber GN. Defective translational control facilitates vesicular stomatitis virus oncolysis. Cancer Cell. 5: 51-65. PMID 14749126 DOI: 10.1016/S1535-6108(03)00330-1  1
2003 Porosnicu M, Mian A, Barber GN. The oncolytic effect of recombinant vesicular stomatitis virus is enhanced by expression of the fusion cytosine deaminase/uracil phosphoribosyltransferase suicide gene. Cancer Research. 63: 8366-76. PMID 14678998  1
2003 Obuchi M, Fernandez M, Barber GN. Development of recombinant vesicular stomatitis viruses that exploit defects in host defense to augment specific oncolytic activity. Journal of Virology. 77: 8843-56. PMID 12885903 DOI: 10.1128/JVI.77.16.8843-8856.2003  1
2003 Saunders LR, Barber GN. The dsRNA binding protein family: critical roles, diverse cellular functions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 961-83. PMID 12773480 DOI: 10.1096/fj.02-0958rev  1
2003 Blanchard E, Brand D, Roingeard P, Ezelle HJ, Markovic D, Barber GN. Endogenous virus and hepatitis C virus-like particle budding in BHK-21 cells (multiple letters) Journal of Virology. 77: 3888-3889. PMID 12610167 DOI: 10.1128/JVI.77.6.3888-3889.2003  1
2003 Ogilvie VC, Wilson BJ, Nicol SM, Morrice NA, Saunders LR, Barber GN, Fuller-Pace FV. The highly related DEAD box RNA helicases p68 and p72 exist as heterodimers in cells. Nucleic Acids Research. 31: 1470-80. PMID 12595555 DOI: 10.1093/nar/gkg236  1
2003 Ghosh SK, Wood C, Boise LH, Mian AM, Deyev VV, Feuer G, Toomey NL, Shank NC, Cabral L, Barber GN, Harrington WJ. Potentiation of TRAIL-induced apoptosis in primary effusion lymphoma through azidothymidine-mediated inhibition of NF-kappa B. Blood. 101: 2321-7. PMID 12406882 DOI: 10.1182/blood-2002-08-2525  1
2002 Ezelle HJ, Markovic D, Barber GN. Generation of hepatitis C virus-like particles by use of a recombinant vesicular stomatitis virus vector. Journal of Virology. 76: 12325-34. PMID 12414973 DOI: 10.1128/JVI.76.23.12325-12334.2002  1
2002 Vorburger SA, Pataer A, Yoshida K, Barber GN, Xia W, Chiao P, Ellis LM, Hung MC, Swisher SG, Hunt KK. Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis. Oncogene. 21: 6278-88. PMID 12214268 DOI: 10.1038/sj.onc.1205761  1
2002 Grandvaux N, Servant MJ, tenOever B, Sen GC, Balachandran S, Barber GN, Lin R, Hiscott J. Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes. Journal of Virology. 76: 5532-9. PMID 11991981 DOI: 10.1128/JVI.76.11.5532-5539.2002  1
2002 Pataer A, Vorburger SA, Barber GN, Chada S, Mhashilkar AM, Zou-Yang H, Stewart AL, Balachandran S, Roth JA, Hunt KK, Swisher SG. Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR). Cancer Research. 62: 2239-43. PMID 11956076  1
2002 Fernandez M, Porosnicu M, Markovic D, Barber GN. Genetically engineered vesicular stomatitis virus in gene therapy: application for treatment of malignant disease. Journal of Virology. 76: 895-904. PMID 11752178 DOI: 10.1128/JVI.76.2.895-904.2002  1
2001 Toomey NL, Deyev VV, Wood C, Boise LH, Scott D, Liu LH, Cabral L, Podack ER, Barber GN, Harrington WJ. Induction of a TRAIL mediated suicide program by interferon alpha in primary effusion lymphoma Oncogene. 20: 7029-7040. PMID 11704827 DOI: 10.1038/sj.onc.1204895  1
2001 Saunders LR, Perkins DJ, Balachandran S, Michaels R, Ford R, Mayeda A, Barber GN. Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR. The Journal of Biological Chemistry. 276: 32300-12. PMID 11438536 DOI: 10.1074/jbc.M104207200  1
2001 Polyak SJ, Khabar KS, Paschal DM, Ezelle HJ, Duverlie G, Barber GN, Levy DE, Mukaida N, Gretch DR. Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. Journal of Virology. 75: 6095-106. PMID 11390611 DOI: 10.1128/JVI.75.13.6095-6106.2001  1
2001 Lin R, Genin P, Mamane Y, Sgarbanti M, Battistini A, Harrington WJ, Barber GN, Hiscott J. HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators. Oncogene. 20: 800-11. PMID 11314014 DOI: 10.1038/sj.onc.1204163  1
2001 Barber GN. Host defense, viruses and apoptosis Cell Death and Differentiation. 8: 113-126. PMID 11313713 DOI: 10.1038/sj.cdd.4400823  1
2001 Balachandran S, Porosnicu M, Barber GN. Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, ras, or myc function and involves the induction of apoptosis Journal of Virology. 75: 3474-3479. PMID 11238874 DOI: 10.1128/JVI.75.7.3474-3479.2001  1
2001 Ezelle HJ, Balachandran S, Sicheri F, Polyak SJ, Barber GN. Analyzing the mechanisms of interferon-induced apoptosis using CrmA and hepatitis C virus NS5A Virology. 281: 124-137. PMID 11222103 DOI: 10.1006/viro.2001.0815  1
2001 Saunders LR, Jurecic V, Barber GN. The 90- and 110-kDa human NFAR proteins are translated from two differentially spliced mRNAs encoded on chromosome 19p13. Genomics. 71: 256-9. PMID 11161820 DOI: 10.1006/geno.2000.6423  1
2000 Balachandran S, Barber GN. Vesicular stomatitis virus (VSV) therapy of tumors Iubmb Life. 50: 135-138. PMID 11185959  1
2000 Barber GN. The interferons and cell death: Guardians of the cell or accomplices of apoptosis? Seminars in Cancer Biology. 10: 103-111. PMID 10936061 DOI: 10.1006/scbi.2000.0313  1
2000 Balachandran S, Roberts PC, Brown LE, Truong H, Pattnaik AK, Archer DR, Barber GN. Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. Immunity. 13: 129-41. PMID 10933401  1
2000 Heylbroeck C, Balachandran S, Servant MJ, DeLuca C, Barber GN, Lin R, Hiscott J. The IRF-3 transcription factor mediates Sendai virus-induced apoptosis. Journal of Virology. 74: 3781-92. PMID 10729153 DOI: 10.1128/JVI.74.8.3781-3792.2000  1
2000 Balachandran S, Roberts PC, Kipperman T, Bhalla KN, Compans RW, Archer DR, Barber GN. Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/caspase-8 death signaling pathway Journal of Virology. 74: 1513-1523. PMID 10627563 DOI: 10.1128/JVI.74.3.1513-1523.2000  1
1999 Taylor DR, Shi ST, Romano PR, Barber GN, Lai MMC. Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein Science. 285: 107-110. PMID 10390359 DOI: 10.1126/science.285.5424.107  1
1999 Jagus R, Joshi B, Barber GN. PKR, apoptosis and cancer International Journal of Biochemistry and Cell Biology. 31: 123-138. PMID 10216948 DOI: 10.1016/S1357-2725(98)00136-8  1
1998 Balachandran S, Kim CN, Yeh WC, Mak TW, Bhalla K, Barber GN. Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling Embo Journal. 17: 6888-6902. PMID 9843495  1
1998 Abraham N, Jaramillo ML, Duncan PI, Méthot N, Icely PL, Stojdl DF, Barber GN, Bell JC. The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia Experimental Cell Research. 244: 394-404. PMID 9806790 DOI: 10.1006/excr.1998.4201  1
1998 Sharp TV, Moonan F, Romashko A, Joshi B, Barber GN, Jagus R. The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation. Virology. 250: 302-15. PMID 9792841 DOI: 10.1006/viro.1998.9365  1
1996 Polyak SJ, Tang N, Wambach M, Barber GN, Katze MG. The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity Journal of Biological Chemistry. 271: 1702-1707. PMID 8576172  1
1995 Romano PR, Green SR, Barber GN, Mathews MB, Hinnebusch AG. Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae. Molecular and Cellular Biology. 15: 365-78. PMID 7799945  1
1995 Barber GN, Jagus R, Meurs EF, Hovanessian AG, Katze MG. Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase Journal of Biological Chemistry. 270: 17423-17428. PMID 7615547 DOI: 10.1074/jbc.270.29.17423  1
1995 Barber GN, Wambach M, Thompson S, Jagus R, Katze MG. Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation Molecular and Cellular Biology. 15: 3138-3146. PMID 7539103  1
1994 Barber GN, Thompson S, Lee TG, Strom T, Jagus R, Darveau A, Katze MG. The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties. Proceedings of the National Academy of Sciences of the United States of America. 91: 4278-82. PMID 7514301  1
1993 Hu SL, Stallard V, Abrams K, Barber GN, Kuller L, Langlois AJ, Morton WR, Benveniste RE. Protection of vaccinia-primed macaques against SIVmne infection by combination immunization with recombinant vaccinia virus and SIVmne gp160. Journal of Medical Primatology. 22: 92-9. PMID 8411113  1
1993 Barber GN, Wambach M, Wong ML, Dever TE, Hinnebusch AG, Katze MG. Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase Proceedings of the National Academy of Sciences of the United States of America. 90: 4621-4625. PMID 8099444  1
1993 Dever TE, Chen JJ, Barber GN, Cigan AM, Feng L, Donahue TF, London IM, Katze MG, Hinnebusch AG. Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast. Proceedings of the National Academy of Sciences of the United States of America. 90: 4616-20. PMID 8099443  1
1993 Barber GN, Edelhoff S, Katze MG, Disteche CM. Chromosomal Assignment of the Interferon-Inducible Double-Stranded RNA-Dependent Protein Kinase (PRKR) to Human Chromosome 2p21-p22 and Mouse Chromosome 17 E2 Genomics. 16: 765-767. PMID 7686883 DOI: 10.1006/geno.1993.1262  1
1993 Meurs EF, Galabru J, Barber GN, Katze MG, Hovanessian AG. Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase Proceedings of the National Academy of Sciences of the United States of America. 90: 232-236. PMID 7678339  1
1993 Black TL, Barber GN, Katze MG. Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNA. Journal of Virology. 67: 791-800. PMID 7678306  1
1992 Hu SL, Abrams K, Barber GN, Moran P, Zarling JM, Langlois AJ, Kuller L, Morton WR, Benveniste RE. Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160. Science (New York, N.Y.). 255: 456-9. PMID 1531159  1
1992 Koromilas AE, Roy S, Barber GN, Katze MG, Sonenberg N. Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase Science. 257: 1685-1689. PMID 1382315  1
1992 Meurs EF, Watanabe Y, Kadereit S, Barber GN, Katze MG, Chong K, Williams BRG, Hovanessian AG. Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth Journal of Virology. 66: 5805-5814. PMID 1382142  1
1992 Barber GN, Tomita J, Garfinkel MS, Meurs E, Hovanessian A, Katze MG. Detection of protein kinase homologues and viral RNA-binding domains utilizing polyclonal antiserum prepared against a baculovirus-expressed ds RNA-activated 68,000-Da protein kinase. Virology. 191: 670-9. PMID 1360180 DOI: 10.1016/0042-6822(92)90242-H  1
1991 Barber GN, Tomita J, Hovanessian AG, Meurs E, Katze MG. Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli Biochemistry. 30: 10356-10361. PMID 1718419  1
1991 Katze MG, Wambach M, Wong ML, Garfinkel M, Meurs E, Chong K, Williams BR, Hovanessian AG, Barber GN. Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system. Molecular and Cellular Biology. 11: 5497-505. PMID 1717830 DOI: 10.1128/MCB.11.11.5497  1
1990 Barber GN, Clegg JCS, Lloyd G. Expression of the Lassa virus nucleocapsid protein in insect cells infected with a recombinant baculovirus: Application to diagnostic assays for Lassa virus infection Journal of General Virology. 71: 19-28. PMID 2406367  1
1989 Lloyd G, Barber GN, Clegg JCS, Kelly P. IDENTIFICATION OF LASSA FEVER VIRUS INFECTION WITH RECOMBINANT NUCLEOCAPSID PROTEIN ANTIGEN The Lancet. 334: 1222. PMID 2572935 DOI: 10.1016/S0140-6736(89)91833-3  1
1987 Barber GN, Clegg JCS, Chamberlain J. Expression of Lassa virus nucleocapsid protein segments in bacteria: purification of high-level expression products and their application in antibody detection Gene. 56: 137-144. PMID 3315857 DOI: 10.1016/0378-1119(87)90166-1  1
1986 Clegg JCS, Barber GN, Chamberlain JF, Oram JD. Expression of Lassa virus nucleocapsid gene fragments in bacteria Medical Microbiology and Immunology. 175: 93-95. PMID 3523185 DOI: 10.1007/BF02122423  1
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