Bryan R. Cullen - Publications

Affiliations: 
Molecular Genetics and Microbiology Duke University, Durham, NC 
Area:
Molecular Biology, Virology Biology

244 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Courtney DG, Tsai K, Bogerd HP, Kennedy EM, Law BA, Emery A, Swanstrom R, Holley CL, Cullen BR. Epitranscriptomic Addition of mC to HIV-1 Transcripts Regulates Viral Gene Expression. Cell Host & Microbe. 26: 217-227.e6. PMID 31415754 DOI: 10.1016/j.chom.2019.07.005  0.72
2019 Courtney DG, Chalem A, Bogerd HP, Law BA, Kennedy EM, Holley CL, Cullen BR. Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression. Mbio. 10. PMID 31186331 DOI: 10.1128/mBio.01209-19  0.72
2018 Mefferd AL, Bogerd HP, Irwan ID, Cullen BR. Insights into the mechanisms underlying the inactivation of HIV-1 proviruses by CRISPR/Cas. Virology. 520: 116-126. PMID 29857168 DOI: 10.1016/j.virol.2018.05.016  0.72
2017 Kennedy EM, Bogerd HP, Kornepati AVR, Kang D, Ghoshal D, Marshall JB, Poling BC, Tsai K, Gokhale NS, Horner SM, Cullen BR. Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. Cell Host & Microbe. 22: 830. PMID 29241043 DOI: 10.1016/j.chom.2017.11.010  0.72
2017 Courtney DG, Kennedy EM, Dumm RE, Bogerd HP, Tsai K, Heaton NS, Cullen BR. Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication. Cell Host & Microbe. 22: 377-386.e5. PMID 28910636 DOI: 10.1016/j.chom.2017.08.004  0.72
2017 Bogerd HP, Kennedy EM, Whisnant AW, Cullen BR. Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity. Mbio. 8. PMID 28096489 DOI: 10.1128/mBio.02125-16  0.72
2016 Kennedy EM, Kornepati AV, Bogerd HP, Cullen BR. Partial reconstitution of the RNAi response in human cells using Drosophila gene products. Rna (New York, N.Y.). PMID 27837013 DOI: 10.1261/rna.059345.116  0.72
2016 Kennedy EM, Bogerd HP, Kornepati AV, Kang D, Ghoshal D, Marshall JB, Poling BC, Tsai K, Gokhale NS, Horner SM, Cullen BR. Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. Cell Host & Microbe. PMID 27117054 DOI: 10.1016/j.chom.2016.04.002  1
2015 Bogerd HP, Kornepati AV, Marshall JB, Kennedy EM, Cullen BR. Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators. Proceedings of the National Academy of Sciences of the United States of America. PMID 26668372 DOI: 10.1073/pnas.1516305112  1
2015 Kennedy EM, Whisnant AW, Kornepati AV, Marshall JB, Bogerd HP, Cullen BR. Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621737 DOI: 10.1073/pnas.1513421112  1
2015 Skalsky RL, Cullen BR. EBV Noncoding RNAs. Current Topics in Microbiology and Immunology. 391: 181-217. PMID 26428375 DOI: 10.1007/978-3-319-22834-1_6  1
2015 Kennedy EM, Kornepati AV, Mefferd AL, Marshall JB, Tsai K, Bogerd HP, Cullen BR. Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic. Methods (San Diego, Calif.). PMID 26291065 DOI: 10.1016/j.ymeth.2015.08.012  0.72
2015 Mefferd AL, Kornepati AV, Bogerd HP, Kennedy EM, Cullen BR. Expression of CRISPR/Cas single guide RNAs using small tRNA promoters. Rna (New York, N.Y.). 21: 1683-9. PMID 26187160 DOI: 10.1261/rna.051631.115  1
2015 Kang D, Skalsky RL, Cullen BR. EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival. Plos Pathogens. 11: e1004979. PMID 26070070 DOI: 10.1371/journal.ppat.1004979  1
2015 Cullen BR. The virology-RNA biology connection. Rna (New York, N.Y.). 21: 592-4. PMID 25780153 DOI: 10.1261/rna.049882.115  1
2015 Kennedy EM, Cullen BR. Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment. Virology. 479: 213-20. PMID 25759096 DOI: 10.1016/j.virol.2015.02.024  1
2015 Kennedy EM, Bassit LC, Mueller H, Kornepati AV, Bogerd HP, Nie T, Chatterjee P, Javanbakht H, Schinazi RF, Cullen BR. Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease. Virology. 476: 196-205. PMID 25553515 DOI: 10.1016/j.virol.2014.12.001  1
2014 Cullen BR. HIV-1 Packing to Leave. Cell. 159: 975-6. PMID 25416937 DOI: 10.1016/j.cell.2014.11.008  1
2014 Cullen BR. Viruses and RNA interference: issues and controversies. Journal of Virology. 88: 12934-6. PMID 25210170 DOI: 10.1128/JVI.01179-14  1
2014 Furuse Y, Finethy R, Saka HA, Xet-Mull AM, Sisk DM, Smith KL, Lee S, Coers J, Valdivia RH, Tobin DM, Cullen BR. Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. Plos One. 9: e106434. PMID 25184567 DOI: 10.1371/journal.pone.0106434  1
2014 Kennedy EM, Kornepati AV, Goldstein M, Bogerd HP, Poling BC, Whisnant AW, Kastan MB, Cullen BR. Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease. Journal of Virology. 88: 11965-72. PMID 25100830 DOI: 10.1128/JVI.01879-14  1
2014 Skalsky RL, Olson KE, Blair CD, Garcia-Blanco MA, Cullen BR. A "microRNA-like" small RNA expressed by Dengue virus? Proceedings of the National Academy of Sciences of the United States of America. 111: E2359. PMID 24853506 DOI: 10.1073/pnas.1406854111  1
2014 Bogerd HP, Skalsky RL, Kennedy EM, Furuse Y, Whisnant AW, Flores O, Schultz KL, Putnam N, Barrows NJ, Sherry B, Scholle F, Garcia-Blanco MA, Griffin DE, Cullen BR. Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs. Journal of Virology. 88: 8065-76. PMID 24807715 DOI: 10.1128/JVI.00985-14  1
2014 Bogerd HP, Whisnant AW, Kennedy EM, Flores O, Cullen BR. Derivation and characterization of Dicer- and microRNA-deficient human cells. Rna (New York, N.Y.). 20: 923-37. PMID 24757167 DOI: 10.1261/rna.044545.114  1
2014 Pan D, Flores O, Umbach JL, Pesola JM, Bentley P, Rosato PC, Leib DA, Cullen BR, Coen DM. A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. Cell Host & Microbe. 15: 446-56. PMID 24721573 DOI: 10.1016/j.chom.2014.03.004  1
2014 Whisnant AW, Kehl T, Bao Q, Materniak M, Kuzmak J, Löchelt M, Cullen BR. Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus. Journal of Virology. 88: 4679-86. PMID 24522910 DOI: 10.1128/JVI.03587-13  1
2014 Flores O, Kennedy EM, Skalsky RL, Cullen BR. Differential RISC association of endogenous human microRNAs predicts their inhibitory potential. Nucleic Acids Research. 42: 4629-39. PMID 24464996 DOI: 10.1093/nar/gkt1393  1
2014 Parnas O, Corcoran DL, Cullen BR. Analysis of the mRNA targetome of microRNAs expressed by Marek's disease virus. Mbio. 5: e01060-13. PMID 24449754 DOI: 10.1128/mBio.01060-13  1
2014 Skalsky RL, Kang D, Linnstaedt SD, Cullen BR. Evolutionary conservation of primate lymphocryptovirus microRNA targets. Journal of Virology. 88: 1617-35. PMID 24257599 DOI: 10.1128/JVI.02071-13  1
2014 Cullen BR. Interview with Bryan R Cullen Future Virology. 9: 345-350. DOI: 10.2217/fvl.14.17  1
2013 Cullen BR. How do viruses avoid inhibition by endogenous cellular microRNAs? Plos Pathogens. 9: e1003694. PMID 24244153 DOI: 10.1371/journal.ppat.1003694  1
2013 Furuse Y, Ornelles DA, Cullen BR. Persistently adenovirus-infected lymphoid cells express microRNAs derived from the viral VAI and especially VAII RNA. Virology. 447: 140-5. PMID 24210108 DOI: 10.1016/j.virol.2013.08.024  1
2013 Cullen BR, Cherry S, tenOever BR. Is RNA interference a physiologically relevant innate antiviral immune response in mammals? Cell Host & Microbe. 14: 374-8. PMID 24139396 DOI: 10.1016/j.chom.2013.09.011  1
2013 Jin HY, Oda H, Lai M, Skalsky RL, Bethel K, Shepherd J, Kang SG, Liu WH, Sabouri-Ghomi M, Cullen BR, Rajewsky K, Xiao C. MicroRNA-17∼92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways Embo Journal. 32: 2377-2391. PMID 23921550 DOI: 10.1038/emboj.2013.178  1
2013 Majoros WH, Lekprasert P, Mukherjee N, Skalsky RL, Corcoran DL, Cullen BR, Ohler U. MicroRNA target site identification by integrating sequence and binding information. Nature Methods. 10: 630-3. PMID 23708386 DOI: 10.1038/nmeth.2489  1
2013 Whisnant AW, Bogerd HP, Flores O, Ho P, Powers JG, Sharova N, Stevenson M, Chen CH, Cullen BR. In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms. Mbio. 4: e000193. PMID 23592263 DOI: 10.1128/mBio.00193-13  0.72
2013 Flores O, Nakayama S, Whisnant AW, Javanbakht H, Cullen BR, Bloom DC. Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture. Journal of Virology. 87: 6589-603. PMID 23536669 DOI: 10.1128/JVI.00504-13  1
2013 Cullen BR. Making a NeST for a persistent virus. Cell Host & Microbe. 13: 241-2. PMID 23498947 DOI: 10.1016/j.chom.2013.02.016  1
2013 Wahl A, Linnstaedt SD, Esoda C, Krisko JF, Martinez-Torres F, Delecluse HJ, Cullen BR, Garcia JV. A cluster of virus-encoded microRNAs accelerates acute systemic Epstein-Barr virus infection but does not significantly enhance virus-induced oncogenesis in vivo. Journal of Virology. 87: 5437-46. PMID 23468485 DOI: 10.1128/JVI.00281-13  1
2013 Cullen BR. MicroRNAs as mediators of viral evasion of the immune system. Nature Immunology. 14: 205-10. PMID 23416678 DOI: 10.1038/ni.2537  1
2013 Cullen BR. Preface Current Topics in Microbiology and Immunology. 371.  1
2012 Cullen BR. MicroRNA expression by an oncogenic retrovirus. Proceedings of the National Academy of Sciences of the United States of America. 109: 2695-6. PMID 22308505 DOI: 10.1073/pnas.1200328109  1
2012 Skalsky RL, Corcoran DL, Gottwein E, Frank CL, Kang D, Hafner M, Nusbaum JD, Feederle R, Delecluse HJ, Luftig MA, Tuschl T, Ohler U, Cullen BR. The viral and cellular microRNA targetome in lymphoblastoid cell lines. Plos Pathogens. 8: e1002484. PMID 22291592 DOI: 10.1371/journal.ppat.1002484  1
2011 Gottwein E, Corcoran DL, Mukherjee N, Skalsky RL, Hafner M, Nusbaum JD, Shamulailatpam P, Love CL, Dave SS, Tuschl T, Ohler U, Cullen BR. Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines. Cell Host & Microbe. 10: 515-26. PMID 22100165 DOI: 10.1016/j.chom.2011.09.012  1
2011 Cullen BR. Herpesvirus microRNAs: phenotypes and functions. Current Opinion in Virology. 1: 211-5. PMID 21927637 DOI: 10.1016/j.coviro.2011.04.003  1
2011 Skalsky RL, Cullen BR. Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene. Plos One. 6: e24248. PMID 21912681 DOI: 10.1371/journal.pone.0024248  1
2011 Cullen BR. Viruses and microRNAs: RISCy interactions with serious consequences. Genes & Development. 25: 1881-94. PMID 21896651 DOI: 10.1101/gad.17352611  1
2011 Feederle R, Haar J, Bernhardt K, Linnstaedt SD, Bannert H, Lips H, Cullen BR, Delecluse HJ. The members of an Epstein-Barr virus microRNA cluster cooperate to transform B lymphocytes. Journal of Virology. 85: 9801-10. PMID 21752900 DOI: 10.1128/JVI.05100-11  1
2011 Feederle R, Linnstaedt SD, Bannert H, Lips H, Bencun M, Cullen BR, Delecluse HJ. A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus. Plos Pathogens. 7: e1001294. PMID 21379335 DOI: 10.1371/journal.ppat.1001294  1
2011 Bogerd HP, Zhang F, Bieniasz PD, Cullen BR. Human APOBEC3 proteins can inhibit xenotropic murine leukemia virus-related virus infectivity. Virology. 410: 234-9. PMID 21131013 DOI: 10.1016/j.virol.2010.11.011  0.72
2011 Cullen BR. RNA interference does not function as an innate antiviral response in mammalian somatic cells Future Virology. 6: 1381-1384. DOI: 10.2217/fvl.11.112  1
2010 Linnstaedt SD, Gottwein E, Skalsky RL, Luftig MA, Cullen BR. Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus. Journal of Virology. 84: 11670-8. PMID 20844043 DOI: 10.1128/JVI.01248-10  1
2010 Umbach JL, Yen HL, Poon LL, Cullen BR. Influenza A virus expresses high levels of an unusual class of small viral leader RNAs in infected cells. Mbio. 1. PMID 20842206 DOI: 10.1128/mBio.00204-10  1
2010 Umbach JL, Strelow LI, Wong SW, Cullen BR. Analysis of rhesus rhadinovirus microRNAs expressed in virus-induced tumors from infected rhesus macaques. Virology. 405: 592-9. PMID 20655562 DOI: 10.1016/j.virol.2010.06.036  1
2010 Skalsky RL, Cullen BR. Viruses, microRNAs, and host interactions. Annual Review of Microbiology. 64: 123-41. PMID 20477536 DOI: 10.1146/annurev.micro.112408.134243  1
2010 Kelly EJ, Hadac EM, Cullen BR, Russell SJ. MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference. Plos Pathogens. 6: e1000820. PMID 20333250 DOI: 10.1371/journal.ppat.1000820  1
2010 Gottwein E, Cullen BR. A human herpesvirus microRNA inhibits p21 expression and attenuates p21-mediated cell cycle arrest. Journal of Virology. 84: 5229-37. PMID 20219912 DOI: 10.1128/JVI.00202-10  1
2010 Cullen BR. Five questions about viruses and microRNAs. Plos Pathogens. 6: e1000787. PMID 20195463 DOI: 10.1371/journal.ppat.1000787  1
2010 Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR. Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus. Bmc Genomics. 11: 119. PMID 20167119 DOI: 10.1186/1471-2164-11-119  1
2010 Bogerd HP, Karnowski HW, Cai X, Shin J, Pohlers M, Cullen BR. A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs. Molecular Cell. 37: 135-42. PMID 20129062 DOI: 10.1016/j.molcel.2009.12.016  0.72
2010 Umbach JL, Wang K, Tang S, Krause PR, Mont EK, Cohen JI, Cullen BR. Identification of viral microRNAs expressed in human sacral ganglia latently infected with herpes simplex virus 2. Journal of Virology. 84: 1189-92. PMID 19889786 DOI: 10.1128/JVI.01712-09  1
2010 Umbach JL, Cullen BR. In-depth analysis of Kaposi's sarcoma-associated herpesvirus microRNA expression provides insights into the mammalian microRNA-processing machinery. Journal of Virology. 84: 695-703. PMID 19889781 DOI: 10.1128/JVI.02013-09  1
2009 Umbach JL, Nagel MA, Cohrs RJ, Gilden DH, Cullen BR. Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia. Journal of Virology. 83: 10677-83. PMID 19656888 DOI: 10.1128/JVI.01185-09  1
2009 Umbach JL, Cullen BR. The role of RNAi and microRNAs in animal virus replication and antiviral immunity. Genes & Development. 23: 1151-64. PMID 19451215 DOI: 10.1101/gad.1793309  1
2009 Cullen BR. Viral RNAs: lessons from the enemy. Cell. 136: 592-7. PMID 19239880 DOI: 10.1016/j.cell.2009.01.048  1
2009 Cullen BR. Viral and cellular messenger RNA targets of viral microRNAs. Nature. 457: 421-5. PMID 19158788 DOI: 10.1038/nature07757  1
2009 Sullivan CS, Cullen BR. Non-coding regulatory RNAs of the DNA tumor viruses Dna Tumor Viruses. 645-682. DOI: 10.1007/978-0-387-68945-6_25  1
2008 Bogerd HP, Tallmadge RL, Oaks JL, Carpenter S, Cullen BR. Equine infectious anemia virus resists the antiretroviral activity of equine APOBEC3 proteins through a packaging-independent mechanism. Journal of Virology. 82: 11889-901. PMID 18818324 DOI: 10.1128/JVI.01537-08  0.72
2008 Gooch BD, Cullen BR. Functional domain organization of human APOBEC3G. Virology. 379: 118-24. PMID 18639915 DOI: 10.1016/j.virol.2008.06.013  1
2008 Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM, Cullen BR. MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature. 454: 780-3. PMID 18596690 DOI: 10.1038/nature07103  1
2008 Gottwein E, Cullen BR. Viral and cellular microRNAs as determinants of viral pathogenesis and immunity. Cell Host & Microbe. 3: 375-87. PMID 18541214 DOI: 10.1016/j.chom.2008.05.002  1
2008 Bogerd HP, Cullen BR. Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation. Rna (New York, N.Y.). 14: 1228-36. PMID 18456846 DOI: 10.1261/rna.964708  1
2007 Gottwein E, Mukherjee N, Sachse C, Frenzel C, Majoros WH, Chi JT, Braich R, Manoharan M, Soutschek J, Ohler U, Cullen BR. A viral microRNA functions as an orthologue of cellular miR-155. Nature. 450: 1096-9. PMID 18075594 DOI: 10.1038/nature05992  1
2007 Wiegand HL, Cullen BR. Inhibition of alpharetrovirus replication by a range of human APOBEC3 proteins. Journal of Virology. 81: 13694-9. PMID 17913830 DOI: 10.1128/JVI.01646-07  1
2007 Lin J, Cullen BR. Analysis of the interaction of primate retroviruses with the human RNA interference machinery. Journal of Virology. 81: 12218-26. PMID 17855543 DOI: 10.1128/JVI.01390-07  1
2007 Gottwein E, Cullen BR. Protocols for expression and functional analysis of viral microRNAs. Methods in Enzymology. 427: 229-43. PMID 17720488 DOI: 10.1016/S0076-6879(07)27013-2  1
2007 Cullen BR. Immunology. Outwitted by viral RNAs. Science (New York, N.Y.). 317: 329-30. PMID 17641188 DOI: 10.1126/science.1146077  1
2007 Schäfer A, Cai X, Bilello JP, Desrosiers RC, Cullen BR. Cloning and analysis of microRNAs encoded by the primate gamma-herpesvirus rhesus monkey rhadinovirus. Virology. 364: 21-7. PMID 17451774 DOI: 10.1016/j.virol.2007.03.029  1
2007 Bogerd HP, Wiegand HL, Doehle BP, Cullen BR. The intrinsic antiretroviral factor APOBEC3B contains two enzymatically active cytidine deaminase domains. Virology. 364: 486-93. PMID 17434555 DOI: 10.1016/j.virol.2007.03.019  1
2007 Cai X, Cullen BR. The imprinted H19 noncoding RNA is a primary microRNA precursor. Rna (New York, N.Y.). 13: 313-6. PMID 17237358 DOI: 10.1261/rna.351707  1
2007 Hulme AE, Bogerd HP, Cullen BR, Moran JV. Selective inhibition of Alu retrotransposition by APOBEC3G. Gene. 390: 199-205. PMID 17079095 DOI: 10.1016/j.gene.2006.08.032  0.72
2006 Gottwein E, Cai X, Cullen BR. Expression and function of microRNAs encoded by kaposi's sarcoma-associated herpesvirus Cold Spring Harbor Symposia On Quantitative Biology. 71: 357-364. PMID 17381317 DOI: 10.1101/sqb.2006.71.004  1
2006 Cai X, Li G, Laimins LA, Cullen BR. Human papillomavirus genotype 31 does not express detectable microRNA levels during latent or productive virus replication. Journal of Virology. 80: 10890-3. PMID 17041229 DOI: 10.1128/JVI.01175-06  1
2006 Doehle BP, Bogerd HP, Wiegand HL, Jouvenet N, Bieniasz PD, Hunter E, Cullen BR. The betaretrovirus Mason-Pfizer monkey virus selectively excludes simian APOBEC3G from virion particles. Journal of Virology. 80: 12102-8. PMID 17035335 DOI: 10.1128/JVI.01600-06  1
2006 Zeng Y, Cullen BR. Recognition and cleavage of primary microRNA transcripts. Methods in Molecular Biology (Clifton, N.J.). 342: 49-56. PMID 16957366 DOI: 10.1385/1-59745-123-1:49  1
2006 Cullen BR. Enhancing and confirming the specificity of RNAi experiments. Nature Methods. 3: 677-81. PMID 16929311 DOI: 10.1038/nmeth913  1
2006 Cullen BR. Viruses and microRNAs. Nature Genetics. 38: S25-30. PMID 16736021 DOI: 10.1038/ng1793  1
2006 Bogerd HP, Wiegand HL, Hulme AE, Garcia-Perez JL, O'Shea KS, Moran JV, Cullen BR. Cellular inhibitors of long interspersed element 1 and Alu retrotransposition. Proceedings of the National Academy of Sciences of the United States of America. 103: 8780-5. PMID 16728505 DOI: 10.1073/pnas.0603313103  1
2006 Cullen BR. Is RNA interference involved in intrinsic antiviral immunity in mammals? Nature Immunology. 7: 563-7. PMID 16715068 DOI: 10.1038/ni1352  1
2006 Gottwein E, Cai X, Cullen BR. A novel assay for viral microRNA function identifies a single nucleotide polymorphism that affects Drosha processing. Journal of Virology. 80: 5321-6. PMID 16699012 DOI: 10.1128/JVI.02734-05  1
2006 Cai X, Schäfer A, Lu S, Bilello JP, Desrosiers RC, Edwards R, Raab-Traub N, Cullen BR. Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed. Plos Pathogens. 2: e23. PMID 16557291 DOI: 10.1371/journal.ppat.0020023  1
2006 Cai X, Cullen BR. Transcriptional origin of Kaposi's sarcoma-associated herpesvirus microRNAs. Journal of Virology. 80: 2234-42. PMID 16474131 DOI: 10.1128/JVI.80.5.2234-2242.2006  1
2006 Cullen BR. Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors. Journal of Virology. 80: 1067-76. PMID 16414984 DOI: 10.1128/JVI.80.3.1067-1076.2006  1
2006 Bogerd HP, Wiegand HL, Doehle BP, Lueders KK, Cullen BR. APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells. Nucleic Acids Research. 34: 89-95. PMID 16407327 DOI: 10.1093/nar/gkj416  1
2006 Cullen BR. Induction of stable RNA interference in mammalian cells. Gene Therapy. 13: 503-8. PMID 16195700 DOI: 10.1038/sj.gt.3302656  1
2005 Cullen BR. RNAi the natural way. Nature Genetics. 37: 1163-5. PMID 16254559 DOI: 10.1038/ng1105-1163  1
2005 Heitman J, Cullen BR. Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel? Molecular Cell. 19: 145-6. PMID 16039584 DOI: 10.1016/j.molcel.2005.07.001  1
2005 Russell RA, Wiegand HL, Moore MD, Schäfer A, McClure MO, Cullen BR. Foamy virus Bet proteins function as novel inhibitors of the APOBEC3 family of innate antiretroviral defense factors. Journal of Virology. 79: 8724-31. PMID 15994766 DOI: 10.1128/JVI.79.14.8724-8731.2005  0.76
2005 Doehle BP, Schäfer A, Cullen BR. Human APOBEC3B is a potent inhibitor of HIV-1 infectivity and is resistant to HIV-1 Vif. Virology. 339: 281-8. PMID 15993456 DOI: 10.1016/j.virol.2005.06.005  1
2005 Doehle BP, Schäfer A, Wiegand HL, Bogerd HP, Cullen BR. Differential sensitivity of murine leukemia virus to APOBEC3-mediated inhibition is governed by virion exclusion. Journal of Virology. 79: 8201-7. PMID 15956565 DOI: 10.1128/JVI.79.13.8201-8207.2005  1
2005 Zeng Y, Cullen BR. Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. The Journal of Biological Chemistry. 280: 27595-603. PMID 15932881 DOI: 10.1074/jbc.M504714200  1
2005 Cullen BR. Does RNA interference have a future as a treatment for HIV-1 induced disease? Aids Reviews. 7: 22-5. PMID 15875658  1
2005 Dutko JA, Schäfer A, Kenny AE, Cullen BR, Curcio MJ. Inhibition of a yeast LTR retrotransposon by human APOBEC3 cytidine deaminases. Current Biology : Cb. 15: 661-6. PMID 15823539 DOI: 10.1016/j.cub.2005.02.051  0.44
2005 Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 5570-5. PMID 15800047 DOI: 10.1073/pnas.0408192102  1
2005 Zeng Y, Cai X, Cullen BR. Use of RNA polymerase II to transcribe artificial microRNAs. Methods in Enzymology. 392: 371-80. PMID 15644193 DOI: 10.1016/S0076-6879(04)92022-8  1
2005 Cullen BR. Human immunodeficiency virus: nuclear RNA export unwound. Nature. 433: 26-7. PMID 15635396 DOI: 10.1038/433026a  1
2005 Yi R, Doehle BP, Qin Y, Macara IG, Cullen BR. Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. Rna (New York, N.Y.). 11: 220-6. PMID 15613540 DOI: 10.1261/rna.7233305  1
2005 Zeng Y, Yi R, Cullen BR. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. The Embo Journal. 24: 138-48. PMID 15565168 DOI: 10.1038/sj.emboj.7600491  1
2004 Lu S, Cullen BR. Nonsense mediated decay induced by tethered human UPF3B is restricted to the cytoplasm. Rna Biology. 1: 42-7. PMID 17194930  1
2004 Cullen BR. Transcription and processing of human microRNA precursors. Molecular Cell. 16: 861-5. PMID 15610730 DOI: 10.1016/j.molcel.2004.12.002  1
2004 Lu S, Cullen BR. Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis. Journal of Virology. 78: 12868-76. PMID 15542639 DOI: 10.1128/JVI.78.23.12868-12876.2004  1
2004 Cai X, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. Rna (New York, N.Y.). 10: 1957-66. PMID 15525708 DOI: 10.1261/rna.7135204  1
2004 Schäfer A, Bogerd HP, Cullen BR. Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor. Virology. 328: 163-8. PMID 15464836 DOI: 10.1016/j.virol.2004.08.006  1
2004 Zeng Y, Cullen BR. Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. Nucleic Acids Research. 32: 4776-85. PMID 15356295 DOI: 10.1093/nar/gkh824  1
2004 Wiegand HL, Doehle BP, Bogerd HP, Cullen BR. A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins. The Embo Journal. 23: 2451-8. PMID 15152192 DOI: 10.1038/sj.emboj.7600246  1
2004 Cullen BR. Derivation and function of small interfering RNAs and microRNAs. Virus Research. 102: 3-9. PMID 15068874 DOI: 10.1016/j.virusres.2004.01.009  1
2004 Bogerd HP, Doehle BP, Wiegand HL, Cullen BR. A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor. Proceedings of the National Academy of Sciences of the United States of America. 101: 3770-4. PMID 14999100 DOI: 10.1073/pnas.0307713101  1
2004 Cullen BR. Assaying nuclear messenger RNA export in human cells. Methods in Molecular Biology (Clifton, N.J.). 257: 85-92. PMID 14769998 DOI: 10.1385/1-59259-750-5:085  1
2003 Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes & Development. 17: 3011-6. PMID 14681208 DOI: 10.1101/gad.1158803  1
2003 Lee MT, Coburn GA, McClure MO, Cullen BR. Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector. Journal of Virology. 77: 11964-72. PMID 14581533  0.52
2003 Cullen BR. HIV-1 Vif: counteracting innate antiretroviral defenses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 525-7. PMID 14565218 DOI: 10.1016/j.ymthe.2003.08.010  1
2003 Wiegand HL, Lu S, Cullen BR. Exon junction complexes mediate the enhancing effect of splicing on mRNA expression. Proceedings of the National Academy of Sciences of the United States of America. 100: 11327-32. PMID 12972633 DOI: 10.1073/pnas.1934877100  1
2003 Cullen BR. HIV-1 infection: fooling the gatekeeper. Nature Medicine. 9: 1112-3. PMID 12949520 DOI: 10.1038/nm0903-1112  1
2003 Cullen BR. Nuclear mRNA export: insights from virology. Trends in Biochemical Sciences. 28: 419-24. PMID 12932730 DOI: 10.1016/S0968-0004(03)00142-7  1
2003 Zeng Y, Yi R, Cullen BR. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 100: 9779-84. PMID 12902540 DOI: 10.1073/pnas.1630797100  1
2003 Lu S, Cullen BR. Analysis of the stimulatory effect of splicing on mRNA production and utilization in mammalian cells. Rna (New York, N.Y.). 9: 618-30. PMID 12702820 DOI: 10.1261/rna.5260303  1
2003 Coburn GA, Cullen BR. siRNAs: a new wave of RNA-based therapeutics. The Journal of Antimicrobial Chemotherapy. 51: 753-6. PMID 12654731 DOI: 10.1093/jac/dkg166  1
2003 Zeng Y, Cullen BR. Sequence requirements for micro RNA processing and function in human cells. Rna (New York, N.Y.). 9: 112-23. PMID 12554881 DOI: 10.1261/rna.2780503  1
2003 Cullen BR. Nuclear RNA export. Journal of Cell Science. 116: 587-97. PMID 12538759 DOI: 10.1242/jcs.00268  1
2002 Coburn GA, Cullen BR. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. Journal of Virology. 76: 9225-31. PMID 12186906 DOI: 10.1128/JVI.76.18.9225-9231.2002  1
2002 Zeng Y, Cullen BR. RNA interference in human cells is restricted to the cytoplasm. Rna (New York, N.Y.). 8: 855-60. PMID 12166640 DOI: 10.1017/S1355838202020071  1
2002 Cullen BR. RNA interference: antiviral defense and genetic tool. Nature Immunology. 3: 597-9. PMID 12087412 DOI: 10.1038/ni0702-597  1
2002 Zeng Y, Wagner EJ, Cullen BR. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Molecular Cell. 9: 1327-33. PMID 12086629 DOI: 10.1016/S1097-2765(02)00541-5  1
2002 Yi R, Bogerd HP, Wiegand HL, Cullen BR. Both ran and importins have the ability to function as nuclear mRNA export factors. Rna (New York, N.Y.). 8: 180-7. PMID 11911364 DOI: 10.1017/S1355838202012384  1
2002 Ho DN, Coburn GA, Kang Y, Cullen BR, Georgiadis MM. The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. Proceedings of the National Academy of Sciences of the United States of America. 99: 1888-93. PMID 11854490 DOI: 10.1073/pnas.042698599  1
2002 Yi R, Bogerd HP, Cullen BR. Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs. Journal of Virology. 76: 2036-42. PMID 11836381 DOI: 10.1128/jvi.76.5.2036-2042.2002  1
2002 Cullen BR. Using retroviruses to study the nuclear export of mRNA. Results and Problems in Cell Differentiation. 35: 151-68. PMID 11791405  1
2002 Wiegand HL, Coburn GA, Zeng Y, Kang Y, Bogerd HP, Cullen BR. Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes. Molecular and Cellular Biology. 22: 245-56. PMID 11739738  1
2001 Cullen BR. Journey to the center of the cell Cell. 105: 697-700. PMID 11440710 DOI: 10.1016/S0092-8674(01)00392-0  1
2001 Coburn GA, Wiegand HL, Kang Y, Ho DN, Georgiadis MM, Cullen BR. Using viral species specificity to define a critical protein/RNA interaction surface. Genes & Development. 15: 1194-205. PMID 11358864 DOI: 10.1101/gad.888201  1
2001 Cullen BR. A new entry route for HIV Nature Medicine. 7: 20-21. PMID 11135605 DOI: 10.1038/83295  1
2000 Cullen BR. Principles and applications of a tat-based assay for analyzing specific RNA-protein interactions in mammalian cells Methods in Enzymology. 328: 322-329. PMID 11075353  1
2000 Cullen BR. Utility of the secreted placental alkaline phosphatase reporter enzyme Methods in Enzymology. 326: 159-164. PMID 11036641  1
2000 Neufeld KL, Nix DA, Bogerd H, Kang Y, Beckerle MC, Cullen BR, White RL. Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm. Proceedings of the National Academy of Sciences of the United States of America. 97: 12085-90. PMID 11035805 DOI: 10.1073/pnas.220401797  1
2000 Bieniasz PD, Cullen BR. Multiple blocks to human immunodeficiency virus type 1 replication in rodent cells Journal of Virology. 74: 9868-9877. PMID 11024113 DOI: 10.1128/JVI.74.21.9868-9877.2000  1
2000 Bogerd HP, Wlegand HL, Yang J, Cullen BR. Mutational definition of functional domains within the Rev homolog encoded by human endogenous retrovirus K Journal of Virology. 74: 9353-9361. PMID 11000203 DOI: 10.1128/JVI.74.20.9353-9361.2000  1
2000 Kang Y, Bogerd HP, Cullen BR. Analysis of cellular factors that mediate nuclear export of RNAs bearing the Mason-Pfizer monkey virus constitutive transport element. Journal of Virology. 74: 5863-71. PMID 10846066 DOI: 10.1128/JVI.74.13.5863-5871.2000  1
2000 Cullen BR. Nuclear RNA export pathways Molecular and Cellular Biology. 20: 4181-4187. PMID 10825183 DOI: 10.1128/MCB.20.12.4181-4187.2000  1
2000 Cullen BR. Connections between the processing and nuclear export of mRNA: Evidence for an export license? Proceedings of the National Academy of Sciences of the United States of America. 97: 4-6. PMID 10618360 DOI: 10.1073/pnas.97.1.4  1
1999 Yang J, Cullen BR. Structural and functional analysis of the avian leukemia virus constitutive transport element Rna. 5: 1645-1655. PMID 10606274 DOI: 10.1017/S1355838299991616  1
1999 Truant R, Kang Y, Cullen BR. The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal function. The Journal of Biological Chemistry. 274: 32167-71. PMID 10542253 DOI: 10.1074/jbc.274.45.32167  1
1999 Kang Y, Bogerd HP, Yang J, Cullen BR. Analysis of the RNA binding specificity of the human tap protein, a constitutive transport element-specific nuclear RNA export factor. Virology. 262: 200-9. PMID 10489353 DOI: 10.1006/viro.1999.9906  1
1999 Cullen BR. HIV-1 Nef protein: An invitation to a kill Nature Medicine. 5: 985-986. PMID 10470067 DOI: 10.1038/12417  1
1999 Ross TM, Bieniasz PD, Cullen BR. Role of chemokine receptors in HIV-1 infection and pathogenesis Advances in Virus Research. 52: 233-267. PMID 10384237  1
1999 Ross TM, Oran AE, Cullen BR. Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein Current Biology. 9: 613-621. PMID 10375525 DOI: 10.1016/S0960-9822(99)80283-8  1
1999 Kang Y, Cullen BR. The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. Genes & Development. 13: 1126-39. PMID 10323864  1
1999 Truant R, Cullen BR. The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin β-dependent nuclear localization signals Molecular and Cellular Biology. 19: 1210-1217. PMID 9891055  1
1998 Cullen BR. Retroviruses as model systems for the study of nuclear RNA export pathways Virology. 249: 203-210. PMID 9791012 DOI: 10.1006/viro.1998.9331  1
1998 Ross TM, Cullen BR. The ability of HIV type 1 to use CCR-3 as a coreceptor is controlled by envelope V1/V2 sequences acting in conjunction with a CCR-5 tropic V3 loop Proceedings of the National Academy of Sciences of the United States of America. 95: 7682-7686. PMID 9636210 DOI: 10.1073/pnas.95.13.7682  1
1998 Cullen BR. HIV-1 auxiliary proteins: Making connections in a dying cell Cell. 93: 685-692. PMID 9630214 DOI: 10.1016/S0092-8674(00)81431-2  1
1998 Kang Y, Cullen BR. Derivation and functional characterization of a consensus DNA binding sequence for the tas transcriptional activator of simian foamy virus type 1. Journal of Virology. 72: 5502-9. PMID 9621006  1
1998 Ross TM, Bieniasz PD, Cullen BR. Multiple residues contribute to the inability of murine CCR-5 to function as a coreceptor for macrophage-tropic human immunodeficiency virus type 1 isolates Journal of Virology. 72: 1918-1924. PMID 9499044  1
1998 Kang Y, Blair WS, Cullen BR. Identification and functional characterization of a high-affinity Bel-1 DNA binding site located in the human foamy virus internal promoter. Journal of Virology. 72: 504-11. PMID 9420252  1
1998 Bieniasz PD, Cullen BR. Chemokine receptors and human immunodeficiency virus infection Frontiers in Bioscience : a Journal and Virtual Library. 3. PMID 9407151  1
1998 Cullen BR. Posttranscriptional regulation by the HIV-1 rev protein Seminars in Virology. 8: 327-334. DOI: 10.1006/smvy.1997.0135  1
1997 Hua J, Cullen BR. Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus Nef use distinct but overlapping target sites for downregulation of cell surface CD4 Journal of Virology. 71: 6742-6748. PMID 9261398  1
1997 Blair WS, Cullen BR. A yeast TATA-binding protein mutant that selectively enhances gene expression from weak RNA polymerase II promoters Molecular and Cellular Biology. 17: 2888-2896. PMID 9111361  1
1996 Cullen BR. HIV-1: Is Nef a PAK animal? Current Biology. 6: 1557-1559. PMID 8994811  1
1996 Hua J, Cafffey JJ, Cullen BR. Functional consequences of natural sequence variation in the activation domain of HIV-1 Rev Virology. 222: 423-429. PMID 8806526 DOI: 10.1006/viro.1996.0439  1
1996 Fengling HE, Blair WS, Fukushima J, Cullen BR. The human foamy virus Bel-1 transcription factor is a sequence-specific DNA binding protein Journal of Virology. 70: 3902-3908. PMID 8648727  1
1996 Fridell RA, Bogerd HP, Cullen BR. Nuclear export of late HIV-1 mRNAs occurs via a cellular protein export pathway Proceedings of the National Academy of Sciences of the United States of America. 93: 4421-4424. PMID 8633082 DOI: 10.1073/pnas.93.9.4421  1
1996 Blair WS, Fridell RA, Cullen BR. Synergistic enhancement of both initiation and elongation by acidic transcription activation domains Embo Journal. 15: 1658-1665. PMID 8612590  1
1996 Cullen BR. New trick from an old foe Nature. 379: 208-209. PMID 8538783 DOI: 10.1038/379208a0  1
1995 Cullen BR. Regulation of HIV gene expression Aids (London, England). 9. PMID 8819566  1
1995 Madore SJ, Cullen BR. Functional Similarities between HIV-1 Tat and DNA Sequence-Specific Transcriptional Activators Virology. 206: 1150-1154. PMID 7856090 DOI: 10.1006/viro.1995.1041  1
1995 Fridell RA, Harding LS, Bogerd HP, Cullen BR. Identification of a Novel Human Zinc Finger Protein That Specifically Interacts with the Activation Domain of Lentiviral Tat Proteins Virology. 209: 347-357. PMID 7778269 DOI: 10.1006/viro.1995.1266  1
1995 Bogerd HP, Fridell RA, Madore S, Cullen BR. Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins Cell. 82: 485-494. PMID 7634337 DOI: 10.1016/0092-8674(95)90437-9  1
1994 Blair WS, Bogerd H, Cullen BR. Genetic analysis indicates that the human foamy virus Bel-1 protein contains a transcription activation domain of the acidic class Journal of Virology. 68: 3803-3808. PMID 8189518  1
1994 Cullen BR. The Role of Nef in the Replication Cycle of the Human and Simian Immunodeficiency Viruses Virology. 205: 1-6. PMID 7975204 DOI: 10.1006/viro.1994.1613  1
1994 Blair WS, Bogerd HP, Madore SJ, Cullen BR. Mutational analysis of the transcription activation domain of RelA: Identification of a highly synergistic minimal acidic activation module Molecular and Cellular Biology. 14: 7226-7234. PMID 7935437  1
1994 Sanfridson A, Cullen BR, Doyle C. The simian immunodeficiency virus Nef protein promotes degradation of CD4 in human T cells Journal of Biological Chemistry. 269: 3917-3920. PMID 7905875  1
1994 Cullen BR. RNA-sequence-mediated gene regulation in HIV-1 Infectious Agents and Disease. 3: 68-76. PMID 7812657  1
1994 Cullen BR, Heitman J. Chaperoning a pathogen Nature. 372: 319-320. PMID 7526224  1
1994 Madore SJ, Tiley LS, Malim MH, Cullen BR. Sequence Requirements for Rev Multimerization in Vivo Virology. 202: 186-194. PMID 7516596 DOI: 10.1006/viro.1994.1334  1
1993 Cullen BR. Does HIV-1 Tat induce a change in viral initiation rights? Cell. 73: 417-420. PMID 8490957 DOI: 10.1016/0092-8674(93)90126-B  1
1993 Garrett ED, He F, Bogerd HP, Cullen BR. Transcriptional trans activators of human and simian foamy viruses contain a small, highly conserved activation domain Journal of Virology. 67: 6824-6827. PMID 8411385  1
1993 Madore SJ, Cullen BR. Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function Journal of Virology. 67: 3703-3711. PMID 8389901  1
1993 He F, Sun JD, Garrett ED, Cullen BR. Functional organization of the Bel-1 trans activator of human foamy virus Journal of Virology. 67: 1896-1904. PMID 8383217  1
1993 Bogerd HP, Fridell RA, Blair WS, Cullen BR. Genetic evidence that the Tat proteins of human immunodeficiency virus types 1 and 2 can multimerize in the eukaryotic cell nucleus Journal of Virology. 67: 5030-5034. PMID 8331738  1
1993 Fridell RA, Partin KM, Carpenter S, Cullen BR. Identification of the activation domain of equine infectious anemia virus rev. Journal of Virology. 67: 7317-23. PMID 8230455  1
1993 Malim MH, Cullen BR. Rev and the fate of pre-mRNA in the nucleus: Implications for the regulation of RNA processing in eukaryotes Molecular and Cellular Biology. 13: 6180-6189. PMID 8105371  1
1992 Garrett ED, Cullen BR. Comparative analysis of Rev function in human immunodeficiency virus types 1 and 2 Journal of Virology. 66: 4288-4294. PMID 1602545  1
1992 Cullen BR, Malim MH. [31] Secreted placental alkaline phosphatase as a eukaryotic reporter gene Methods in Enzymology. 216: 362-368. PMID 1479908 DOI: 10.1016/0076-6879(92)16033-G  1
1992 Bogerd HP, Tiley LS, Cullen BR. Specific binding of the human T-cell leukemia virus type I Rex protein to a short RNA sequence located within the Rex-response element Journal of Virology. 66: 7572-7575. PMID 1433531  1
1992 Cullen BR. Mechanism of action of regulatory proteins encoded by complex retroviruses Microbiological Reviews. 56: 375-394. PMID 1406488  1
1992 Keller A, Garrett ED, Cullen BR. The Bel-1 protein of human foamy virus activates human immunodeficiency virus type 1 gene expression via a novel DNA target site Journal of Virology. 66: 3946-3949. PMID 1316494  1
1992 Tiley LS, Cullen BR. Structural and functional analysis of the visna virus rev-response element Journal of Virology. 66: 3609-3615. PMID 1316470  1
1992 Cullen BR, Garrett ED. A comparison of regulatory features in primate lentiviruses Aids Research and Human Retroviruses. 8: 387-393. PMID 1315144  1
1991 Malim MH, McCarn DF, Tiley LS, Cullen BR. Mutational definition of the human immunodeficiency virus type 1 Rev activation domain Journal of Virology. 65: 4248-4254. PMID 2072452  1
1991 Malim MH, Cullen BR. HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency Cell. 65: 241-248. PMID 2015625 DOI: 10.1016/0092-8674(91)90158-U  1
1991 Cullen BR. Regulation of gene expression in the human immunodeficiency virus type 1 Advances in Virus Research. 40: 1-17. PMID 1957716  1
1991 Cullen BR, Malim MH. The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators Trends in Biochemical Sciences. 16: 346-350. PMID 1949157 DOI: 10.1016/0968-0004(91)90141-H  1
1991 Riske FJ, Cullen BR, Chizzonite R. Characterization of human interferon-γ and human interleukin-2 from recombinant mammalian cell lines and peripheral blood lymphocytes Lymphokine and Cytokine Research. 10: 213-218. PMID 1909189  1
1991 Hwang SS, Boyle TJ, Lyerly HK, Cullen BR. Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1 Science. 253: 71-74. PMID 1905842  1
1991 Brown PH, Tiley LS, Cullen BR. Efficient Polyadenylation within the Human Immunodeficiency Virus Type 1 Long Terminal Repeat Requires Flanking US-Specific Sequences Journal of Virology. 65: 3340-3343. PMID 1851882  1
1991 Cullen BR. The positive effect of the negative factor Nature. 351: 698-699. PMID 1829506  1
1991 Garrett ED, Tiley LS, Cullen BR. Rev activates expression of the human immunodeficiency virus type 1 vif and vpr gene products Journal of Virology. 65: 1653-1657. PMID 1825343  1
1991 Cullen BR. Regulation of human immunodeficiency virus replication Annual Review of Microbiology. 45: 219-250. PMID 1741615  1
1991 Weinberg JB, Matthews TJ, Cullen BR, Malim MH. Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes Journal of Experimental Medicine. 174: 1477-1482. PMID 1720811  1
1991 Brown PH, Tiley LS, Cullen BR. Effect of RNA secondary structure on polyadenylation site selection Genes and Development. 5: 1277-1284. PMID 1712333  1
1991 Cullen BR. Regulation of HIV-1 gene expression Faseb Journal. 5: 2361-2368. PMID 1712325  1
1991 Garcia-Blanco MA, Cullen BR. Molecular basis of latency in pathogenic human viruses Science. 254: 815-820. PMID 1658933  1
1991 Tiley LS, Malim MH, Cullen BR. Conserved functional organization of the human immunodeficiency virus type 1 and visna virus Rev proteins Journal of Virology. 65: 3877-3881. PMID 1645796  1
1990 Le SY, Malim MH, Cullen BR, Maizel JV. A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses Nucleic Acids Research. 18: 1613-1623. PMID 2326200 DOI: 10.1093/nar/18.6.1613  1
1990 Cullen BR. The HIV-1 Tat protein: An RNA sequence-specific processivity factor? Cell. 63: 655-657. PMID 2225069 DOI: 10.1016/0092-8674(90)90129-3  1
1990 Tiley LS, Brown PH, Cullen BR. Does the human immunodeficiency virus tat trans-activator contain a discrete activation domain? Virology. 178: 560-567. PMID 2219707 DOI: 10.1016/0042-6822(90)90354-T  1
1990 Cullen BR, Greene WC. Functions of the auxiliary gene products of the human immunodeficiency virus type 1 Virology. 178: 1-5. PMID 2202146 DOI: 10.1016/0042-6822(90)90373-Y  1
1989 Bohnlein S, Hauber J, Cullen BR. Identification of a U5-specific sequence required for efficient polyadenylation within the human immunodeficiency virus long terminal repeat Journal of Virology. 63: 421-424. PMID 2908926  1
1989 Malim MH, Böhnlein S, Hauber J, Cullen BR. Functional dissection of the HIV-1 Rev trans-activator-Derivation of a trans-dominant repressor of Rev function Cell. 58: 205-214. PMID 2752419 DOI: 10.1016/0092-8674(89)90416-9  1
1989 Cullen BR, Greene WC. Regulatory pathways governing HIV-1 replication Cell. 58: 423-426. PMID 2569361 DOI: 10.1016/0092-8674(89)90420-0  1
1989 Hauber J, Malim MH, Cullen BR. Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein Journal of Virology. 63: 1181-1187. PMID 2536828  1
1988 Malim MH, Hauber J, Fenrick R, Cullen BR. Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes Nature. 335: 181-183. PMID 3412474  1
1988 Cullen BR. Expression of a cloned human interleukin-2 cDNA is enhanced by the substitution of a heterologous mRNA leader region Dna. 7: 645-650. PMID 3265909  1
1988 Goldstein AM, Marcon L, Cullen BR, Nelson DL. A competitive Enzyme-Linked Immunoassay (ELISA) for the measurement of soluble human interleukin-2 receptors (IL-2R, Tac protein) Journal of Immunological Methods. 107: 103-109. PMID 3125256 DOI: 10.1016/0022-1759(88)90015-4  1
1988 Hauber J, Bouvier M, Malim MH, Cullen BR. Phosphorylation of the rev gene product of human immunodeficiency virus type 1 Journal of Virology. 62: 4801-4804. PMID 2846891  1
1988 Hauber J, Cullen BR. Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat Journal of Virology. 62: 673-679. PMID 2828663  1
1987 Cullen BR. [71] Use of eukaryotic expression technology in the functional analysis of cloned genes Methods in Enzymology. 152: 684-704. PMID 3657593 DOI: 10.1016/0076-6879(87)52074-2  1
1987 Hauber J, Perkins A, Heimer EP, Cullen BR. Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events Proceedings of the National Academy of Sciences of the United States of America. 84: 6364-6368. PMID 3476953  1
1986 Cullen BR. Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism Cell. 46: 973-982. PMID 3530501 DOI: 10.1016/0092-8674(86)90696-3  1
1986 Katz RA, Cullen BR, Malavarca R, Skalka AM. Role of the avian retrovirus mRNA leader in expression: Evidence for novel translational control Molecular and Cellular Biology. 6: 372-379. PMID 3023842  1
1986 Cullen BR. A rapid and simple procedure for the preparation of homogeneously labeled DNA probes Gene. 43: 305-310. PMID 3017814 DOI: 10.1016/0378-1119(86)90221-0  1
1985 Ju G, Cullen BR. The role of avian retroviral LTRs in the regulation of gene expression and viral replication Advances in Virus Research. 30: 179-223. PMID 3008523  1
1985 Cullen BR, Katz RA, Ju G. Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection Molecular and Cellular Biology. 5: 1804-1807. PMID 2991753  1
1985 Cullen BR, Raymond K, Ju G. Functional analysis of the transcription control region located within the avian retroviral long terminal repeat Molecular and Cellular Biology. 5: 438-447. PMID 2985953  1
1985 Cullen BR, Raymond K, Ju G. Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity Journal of Virology. 53: 515-521. PMID 2982034  1
1984 Cullen BR, Lomedico PT, Ju G. Transcriptional interference in avian retroviruses - implications for the promoter insertion model of leukaemogenesis Nature. 307: 241-245. PMID 6363938 DOI: 10.1038/307241a0  1
1983 Cullen BR, Skalka AM, Ju G. Endogenous avian retroviruses contain deficient promoter and leader sequences Proceedings of the National Academy of Sciences of the United States of America. 80: 2946-2950. PMID 6574464  1
1982 Cullen BR, Kopchick JJ, Stacey DW. Effect of intron size on splicing efficiency in retroviral transcripts Nucleic Acids Research. 10: 6177-6190. PMID 6292870 DOI: 10.1093/nar/10.19.6177  1
1981 Kopchick JJ, Cullen BR, Stacey DW. Rapid analysis of small nucleic acid samples by gel electrophoresis Analytical Biochemistry. 115: 419-423. PMID 6272606 DOI: 10.1016/0003-2697(81)90027-0  1
1980 Cullen BR, Emigholz K, Monahan JJ. Protein patterns of early mouse embryos during development. Differentiation; Research in Biological Diversity. 17: 151-60. PMID 7450326  1
1980 Fasy TM, Cullen BR, Luk D, Bick MD. Studies on the enhanced interaction of halodeoxyuridine-substituted DNAs with H1 histones and other polypeptides Journal of Biological Chemistry. 255: 1380-1387. PMID 7354034  1
1978 Cullen BR, Bick MD. Bromodeoxyuridine induction of deoxycytidine deaminase activity in a hamster cell line Bba Section Nucleic Acids and Protein Synthesis. 517: 158-168. PMID 623754 DOI: 10.1016/0005-2787(78)90043-6  1
1976 Cullen BR, Bick MD. Thermal denaturation of DNA from bromodeoxyuridine substituted cells Nucleic Acids Research. 3: 49-62. PMID 1250706  1
1976 Bick MD, Cullen BR. Bromodeoxyuridine inhibition of Friend leukemia cell induction by butyric acid: Time course of inhibition, reversal, and effect of other base analogs Somatic Cell Genetics. 2: 545-558. DOI: 10.1007/BF01542691  1
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