Victor Nizet - Publications

1997- Pediatrics and Pharmacy University of California, San Diego, La Jolla, CA 
Biology, Microbiology, Immunology, Pharmacology

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Year Citation  Score
2024 Menon ND, Poudel S, Sastry AV, Rychel K, Szubin R, Dillon N, Tsunemoto H, Hirose Y, Nair BG, Kumar GB, Palsson BO, Nizet V. Independent component analysis reveals 49 independently modulated gene sets within the global transcriptional regulatory architecture of multidrug-resistant . Msystems. e0060623. PMID 38189271 DOI: 10.1128/msystems.00606-23  0.808
2023 Bjånes E, Koh T, Qayum T, Zurich R, McCabe S, Hampel K, Cartwright L, Nizet V. Exploring Roles of the Polysaccharide Capsule in Pathogenesis of Hypervirulent Clinical Isolate Lac-4. Antibiotics (Basel, Switzerland). 13. PMID 38275320 DOI: 10.3390/antibiotics13010010  0.325
2023 McCabe S, Bjånes E, Hendriks A, Wang Z, van Sorge NM, Pill-Pepe L, Bautista L, Chu E, Codée JDC, Fairman J, Kapoor N, Uchiyama S, Nizet V. The Group A Streptococcal Vaccine Candidate VAX-A1 Protects against Group B Infection via Cross-Reactive IgG Targeting Virulence Factor C5a Peptidase. Vaccines. 11. PMID 38140215 DOI: 10.3390/vaccines11121811  0.743
2023 Askarian F, Tsai CM, Cordara G, Zurich RH, Bjånes E, Golten O, Vinther Sørensen H, Kousha A, Meier A, Chikwati E, Bruun JA, Ludviksen JA, Choudhury B, Trieu D, Davis S, ... ... Nizet V, et al. Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against pneumonia. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301538120. PMID 37459522 DOI: 10.1073/pnas.2301538120  0.802
2023 Hirose Y, Poudel S, Sastry AV, Rychel K, Lamoureux CR, Szubin R, Zielinski DC, Lim HG, Menon ND, Bergsten H, Uchiyama S, Hanada T, Kawabata S, Palsson BO, Nizet V. Elucidation of independently modulated genes in reveals carbon sources that control its expression of hemolytic toxins. Msystems. e0024723. PMID 37278526 DOI: 10.1128/msystems.00247-23  0.813
2023 Kumaraswamy M, Riestra A, Flores A, Uchiyama S, Dahesh S, Bondsäter G, Nilsson V, Chang M, Seo H, Sakoulas G, Nizet V. Unrecognized Potent Activities of Colistin Against Clinically Important + Enterobacteriaceae Revealed in Synergy with Host Immunity. Biorxiv : the Preprint Server For Biology. PMID 36993410 DOI: 10.1101/2023.03.21.533661  0.835
2023 Mu A, Klare WP, Baines SL, Ignatius Pang CN, Guérillot R, Harbison-Price N, Keller N, Wilksch J, Nhu NTK, Phan MD, Keller B, Nijagal B, Tull D, Dayalan S, Chua HHC, ... ... Nizet V, et al. Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature Communications. 14: 1530. PMID 36934086 DOI: 10.1038/s41467-023-37200-w  0.593
2023 Anderson E, Nair B, Nizet V, Kumar G. Man vs Microbes - The Race of the Century. Journal of Medical Microbiology. 72. PMID 36748622 DOI: 10.1099/jmm.0.001646  0.814
2023 Barajas-Mora EM, Lee L, Lu H, Valderrama JA, Bjanes E, Nizet V, Feeney AJ, Hu M, Murre C. Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens. Nature Immunology. PMID 36717722 DOI: 10.1038/s41590-022-01402-z  0.603
2023 Kumaraswamy M, Coady A, Szubin R, Martin TC, Palsson B, Nizet V, Monk JM. Comprehensive whole genome sequencing with hybrid assembly of multi-drug resistant isolate causing cerebral abscess. Current Research in Microbial Sciences. 4: 100180. PMID 36685102 DOI: 10.1016/j.crmicr.2023.100180  0.744
2022 Bergmann R, Gulotta G, Andreoni F, Sumitomo T, Kawabata S, Zinkernagel AS, Chhatwal GS, Nizet V, Rohde M, Uchiyama S. The group A interleukin-8 protease SpyCEP promotes bacterial intracellular survival by evasion of autophagy. Infectious Microbes & Diseases. 4: 116-123. PMID 37333426 DOI: 10.1097/im9.0000000000000098  0.766
2022 Siew R, Ou TL, Dahesh S, Akong K, Nizet V. Bicarbonate Effects on Antibacterial Immunity and Mucus Glycobiology in the Cystic Fibrosis Lung: A Review With Selected Experimental Observations. Infectious Microbes & Diseases. 4: 103-110. PMID 36793929 DOI: 10.1097/im9.0000000000000101  0.794
2022 Poudel S, Hefner Y, Szubin R, Sastry A, Gao Y, Nizet V, Palsson BO. Coordination of CcpA and CodY Regulators in Staphylococcus aureus USA300 Strains. Msystems. e0048022. PMID 36321827 DOI: 10.1128/msystems.00480-22  0.775
2022 Thomas SP, Denizer E, Zuffa S, Best BM, Bode L, Chambers CD, Dorrestein PC, Liu GY, Momper JD, Nizet V, Tsunoda SM, Tremoulet AH. Transfer of antibiotics and their metabolites in human milk: implications for infant health and microbiota. Pharmacotherapy. PMID 36181712 DOI: 10.1002/phar.2732  0.56
2022 Spiegelman L, Bahn-Suh A, Montaño ET, Zhang L, Hura GL, Patras KA, Kumar A, Tezcan FA, Nizet V, Tsutakawa SE, Ghosh P. Strengthening of enterococcal biofilms by Esp. Plos Pathogens. 18: e1010829. PMID 36103556 DOI: 10.1371/journal.ppat.1010829  0.698
2022 Kapoor N, Uchiyama S, Pill L, Bautista L, Sedra A, Yin L, Regan M, Chu E, Rabara T, Wong M, Davey P, Fairman J, Nizet V. Non-Native Amino Acid Click Chemistry-Based Technology for Site-Specific Polysaccharide Conjugation to a Bacterial Protein Serving as Both Carrier and Vaccine Antigen. Acs Omega. 7: 24111-24120. PMID 35874267 DOI: 10.1021/acsomega.1c07360  0.61
2022 Kolesinski P, Wang KC, Hirose Y, Nizet V, Ghosh P. An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37. Elife. 11. PMID 35726694 DOI: 10.7554/eLife.77989  0.714
2022 Hirose Y, Kolesinski P, Hiraoka M, Uchiyama S, Zurich RH, Kumaraswamy M, Bjanes E, Ghosh P, Kawabata S, Nizet V. Contribution of Streptococcus pyogenes M87 protein to innate immune resistance and virulence. Microbial Pathogenesis. 105636. PMID 35724830 DOI: 10.1016/j.micpath.2022.105636  0.814
2022 Mejia ME, Ottinger S, Vrbanac A, Babu P, Zulk JJ, Moorshead D, Bode L, Nizet V, Patras KA. Human Milk Oligosaccharides Reduce Murine Group B Vaginal Colonization with Minimal Impact on the Vaginal Microbiota. Msphere. 7: e0088521. PMID 34986315 DOI: 10.1128/msphere.00885-21  0.72
2022 Corriden R, Schmidt BE, Olson J, Okerblom J, Masso-Silva JA, Nizet V, Meier A. Dexmedetomidine does not directly inhibit neutrophil extracellular trap production. British Journal of Anaesthesia. 128: e51-e54. PMID 34916052 DOI: 10.1016/j.bja.2021.11.015  0.655
2021 Holland M, Bjanes E, Nizet V, Dillon N. Bicarbonate modulates delafloxacin activity against MDR Staphylococcus aureus and Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy. PMID 34893834 DOI: 10.1093/jac/dkab421  0.762
2021 Yamaguchi M, Kinjo Y, Nizet V. Editorial: Host-Pathogen Interactions During Pneumococcal Infection. Frontiers in Cellular and Infection Microbiology. 11: 752959. PMID 34760720 DOI: 10.3389/fcimb.2021.752959  0.619
2021 Campeau A, Uchiyama S, Sanchez C, Sauceda C, Nizet V, Gonzalez DJ. The S Protein of Group B Is a Critical Virulence Determinant That Impacts the Cell Surface Virulome. Frontiers in Microbiology. 12: 729308. PMID 34721327 DOI: 10.3389/fmicb.2021.729308  0.812
2021 Kumaraswamy M, Wiull K, Joshi B, Sakoulas G, Kousha A, Vaaje-Kolstad G, Johannessen M, Hegstad K, Nizet V, Askarian F. Bacterial Membrane-Derived Vesicles Attenuate Vancomycin Activity against Methicillin-Resistant . Microorganisms. 9. PMID 34683376 DOI: 10.3390/microorganisms9102055  0.828
2021 Golden GJ, Toledo AG, Marki A, Sorrentino JT, Morris C, Riley RJ, Spliid C, Chen Q, Cornax I, Lewis NE, Varki N, Le D, Malmström J, Karlsson C, Ley K, ... Nizet V, et al. Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis. Mbio. e0118121. PMID 34544271 DOI: 10.1128/mBio.01181-21  0.699
2021 Gao NJ, Rodas Lima E, Nizet V. Immunobiology of the Classical Lancefield Group A Streptococcal Carbohydrate Antigen. Infection and Immunity. 89: e0029221. PMID 34543125 DOI: 10.1128/IAI.00292-21  0.809
2021 Rada CC, Mejia-Pena H, Grimsey NJ, Canto Cordova I, Olson J, Wozniak JM, Gonzalez DJ, Nizet V, Trejo J. Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption. Science Signaling. 14: eabc1044. PMID 34516752 DOI: 10.1126/scisignal.abc1044  0.595
2021 Sastry AV, Dillon N, Anand A, Poudel S, Hefner Y, Xu S, Szubin R, Feist AM, Nizet V, Palsson B. Machine Learning of Bacterial Transcriptomes Reveals Responses Underlying Differential Antibiotic Susceptibility. Msphere. 6: e0044321. PMID 34431696 DOI: 10.1128/mSphere.00443-21  0.806
2021 Machado H, Seif Y, Sakoulas G, Olson CA, Hefner Y, Anand A, Jones YZ, Szubin R, Palsson BO, Nizet V, Feist AM. Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus. Communications Biology. 4: 793. PMID 34172889 DOI: 10.1038/s42003-021-02339-z  0.424
2021 Lum GR, Mercado V, van Ens D, Nizet V, Kimmey JM, Patras KA. Hypoxia-Inducible Factor 1 Alpha Is Dispensable for Host Defense of Group B Streptococcus Colonization and Infection. Journal of Innate Immunity. 1-13. PMID 34023827 DOI: 10.1159/000515739  0.821
2021 Ulloa E, Uchiyama S, Gillespie R, Nizet V, Sakoulas G. Ticagrelor Increases Platelet-Mediated Staphylococcus aureus Killing Resulting in Clearance of Bacteremia. The Journal of Infectious Diseases. PMID 33966075 DOI: 10.1093/infdis/jiab146  0.8
2021 Hirose Y, Yamaguchi M, Sumitomo T, Nakata M, Hanada T, Okuzaki D, Motooka D, Mori Y, Kawasaki H, Coady A, Uchiyama S, Hiraoka M, Zurich RH, Amagai M, Nizet V, et al. Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface. Cell Reports. 34: 108924. PMID 33789094 DOI: 10.1016/j.celrep.2021.108924  0.803
2021 Sun J, Uchiyama S, Olson J, Morodomi Y, Cornax I, Ando N, Kohno Y, Kyaw MMT, Aguilar B, Haste NM, Kanaji S, Kanaji T, Rose WE, Sakoulas G, Marth JD, ... Nizet V, et al. Repurposed drugs block toxin-driven platelet clearance by the hepatic Ashwell-Morell receptor to clear bacteremia. Science Translational Medicine. 13. PMID 33762439 DOI: 10.1126/scitranslmed.abd6737  0.798
2021 Askarian F, Uchiyama S, Masson H, Sørensen HV, Golten O, Bunæs AC, Mekasha S, Røhr ÅK, Kommedal E, Ludviksen JA, Arntzen MØ, Schmidt B, Zurich RH, van Sorge NM, Eijsink VGH, ... ... Nizet V, et al. The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection. Nature Communications. 12: 1230. PMID 33623002 DOI: 10.1038/s41467-021-21473-0  0.829
2021 Bjanes E, Nizet V. More than a Pore: Nonlytic Antimicrobial Functions of Complement and Bacterial Strategies for Evasion. Microbiology and Molecular Biology Reviews : Mmbr. 85. PMID 33504655 DOI: 10.1128/MMBR.00177-20  0.362
2021 Saha S, Coady A, Sasmal A, Kawanishi K, Choudhury B, Yu H, Sorensen RU, Inostroza J, Schoenhofen IC, Chen X, Münster-Kühnel A, Sato C, Kitajima K, Ram S, Nizet V, et al. Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae. Mbio. 12. PMID 33468699 DOI: 10.1128/mBio.03226-20  0.753
2021 Cornax I, Zulk J, Olson J, Fulde M, Nizet V, Patras KA. Novel Models of Colonization and Disease Reveal Modest Contributions of M-Like (SCM) Protein. Microorganisms. 9. PMID 33467030 DOI: 10.3390/microorganisms9010183  0.825
2021 Rajput A, Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Seif Y, Lamsa A, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, ... ... Nizet V, et al. Identifying the effect of vancomycin on health care-associated methicillin-resistant Staphylococcus aureus strains using bacteriological and physiological media. Gigascience. 10. PMID 33420779 DOI: 10.1093/gigascience/giaa156  0.797
2020 Liu X, Kimmey JM, Matarazzo L, de Bakker V, Van Maele L, Sirard JC, Nizet V, Veening JW. Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq. Cell Host & Microbe. PMID 33120116 DOI: 10.1016/j.chom.2020.10.001  0.765
2020 Washington A, Varki N, Valderrama JA, Nizet V, Bui JD. Evaluation of IL-17D in Host Immunity to Group A Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 33077643 DOI: 10.4049/jimmunol.1901482  0.591
2020 Brouwer S, Barnett TC, Ly D, Kasper KJ, De Oliveira DMP, Rivera-Hernandez T, Cork AJ, McIntyre L, Jespersen MG, Richter J, Schulz BL, Dougan G, Nizet V, Yuen KY, You Y, et al. Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes. Nature Communications. 11: 5018. PMID 33024089 DOI: 10.1038/s41467-020-18700-5  0.319
2020 Vrbanac A, Patras KA, Jarmusch AK, Mills RH, Shing SR, Quinn RA, Vargas F, Gonzalez DJ, Dorrestein PC, Knight R, Nizet V. Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic. Msystems. 5. PMID 33024048 DOI: 10.1128/mSystems.00340-20  0.805
2020 Sun J, LaRock DL, Skowronski EA, Kimmey JM, Olson J, Jiang Z, O'Donoghue AJ, Nizet V, LaRock CN. The Pseudomonas aeruginosa protease LasB directly activates IL-1β. Ebiomedicine. 60: 102984. PMID 32979835 DOI: 10.1016/j.ebiom.2020.102984  0.811
2020 Wozniak JM, Mills RH, Olson J, Caldera JR, Sepich-Poore GD, Carrillo-Terrazas M, Tsai CM, Vargas F, Knight R, Dorrestein PC, Liu GY, Nizet V, Sakoulas G, Rose W, Gonzalez DJ. Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. Cell. 182: 1311-1327.e14. PMID 32888495 DOI: 10.1016/J.Cell.2020.07.040  0.793
2020 Campeau A, Mills RH, Blanchette M, Bajc K, Malfavon M, Munji RN, Deng L, Hancock B, Patras KA, Olson J, Nizet V, Daneman R, Doran K, Gonzalez DJ. Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B . Msystems. 5. PMID 32843537 DOI: 10.1128/mSystems.00368-20  0.801
2020 Berti A, Rose W, Nizet V, Sakoulas G. Antibiotics and Innate Immunity: A Cooperative Effort Toward the Successful Treatment of Infections. Open Forum Infectious Diseases. 7: ofaa302. PMID 32818143 DOI: 10.1093/Ofid/Ofaa302  0.408
2020 Wilde S, Olivares KL, Nizet V, Hoffman HM, Radhakrishna S, LaRock CN. Opportunistic Invasive Infection by Group A Streptococcus During Anti-Interleukin-6 Immunotherapy. The Journal of Infectious Diseases. PMID 32808035 DOI: 10.1093/Infdis/Jiaa511  0.715
2020 Chen YH, Li SH, Yang YC, Hsu SH, Nizet V, Chang YC. T4 Pili Promote Colonization and Immune Evasion Phenotypes of Nonencapsulated M4 Streptococcus pyogenes. Mbio. 11. PMID 32694142 DOI: 10.1128/Mbio.01580-20  0.588
2020 Woehl JL, Kitamura S, Dillon N, Han Z, Edgar LJ, Nizet V, Wolan DW. An irreversible inhibitor to probe the role of cysteine protease SpeB in evasion of host complement defenses. Acs Chemical Biology. PMID 32662975 DOI: 10.1021/Acschembio.0C00191  0.765
2020 Poudel S, Tsunemoto H, Seif Y, Sastry AV, Szubin R, Xu S, Machado H, Olson CA, Anand A, Pogliano J, Nizet V, Palsson BO. Revealing 29 sets of independently modulated genes in , their regulators, and role in key physiological response. Proceedings of the National Academy of Sciences of the United States of America. PMID 32616573 DOI: 10.1073/Pnas.2008413117  0.776
2020 Lund SJ, Patras KA, Kimmey JM, Yamamura A, Butcher LD, Del Rosario PGB, Hernandez GE, McCoy AM, Lakhdari O, Nizet V, Prince LS. Developmental Immaturity of Siglec Receptor Expression on Neonatal Alveolar Macrophages Predisposes to Severe Group B Streptococcal Infection. Iscience. 23: 101207. PMID 32535023 DOI: 10.1016/J.Isci.2020.101207  0.805
2020 Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. SuFEx-enabled high-throughput medicinal chemistry. Journal of the American Chemical Society. PMID 32479075 DOI: 10.1021/Jacs.9B13652  0.719
2020 Kuang E, Okumura CYM, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA. Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection. Plos Genetics. 16: e1008795. PMID 32392217 DOI: 10.1371/journal.pgen.1008795  0.733
2020 Li Y, Fin A, Rovira A, Su Y, Dippel A, Valderrama A, Riestra A, Nizet V, Hammond MC, Tor Y. Tuning the Innate Immune Response to Cyclic Dinucleotides Using Atomic Mutagenesis. Chembiochem : a European Journal of Chemical Biology. PMID 32346955 DOI: 10.1002/Cbic.202000162  0.781
2020 Patras KA, Coady A, Babu P, Shing SR, Ha AD, Rooholfada E, Brandt SL, Geriak M, Gallo RL, Nizet V. Host Cathelicidin Exacerbates Group B Urinary Tract Infection. Msphere. 5. PMID 32321824 DOI: 10.1128/mSphere.00932-19  0.813
2020 Lawrence SM, Corriden R, Nizet V. How Neutrophils Meet Their End. Trends in Immunology. PMID 32303452 DOI: 10.1016/J.It.2020.03.008  0.723
2020 Salazar MJ, Machado H, Dillon NA, Tsunemoto H, Szubin R, Dahesh S, Pogliano J, Sakoulas G, Palsson BO, Nizet V, Feist AM. Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus. Msystems. 5. PMID 32234776 DOI: 10.1128/mSystems.00828-19  0.777
2020 Chang YC, Nizet V. Siglecs at the Host-Pathogen Interface. Advances in Experimental Medicine and Biology. 1204: 197-214. PMID 32152948 DOI: 10.1007/978-981-15-1580-4_8  0.583
2020 Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, ... ... Nizet V, et al. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. PMID 32103176 DOI: 10.1038/S41586-020-2047-9  0.742
2020 Denholtz M, Zhu Y, He Z, Lu H, Isoda T, Döhrmann S, Nizet V, Murre C. Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program. Genes & Development. PMID 31919189 DOI: 10.1101/Gad.333708.119  0.792
2020 Patras* K, Babu P, Shing S, Ha A, Coady A, Rooholfada E, Brandt S, Geriak M, Gallo R, Nizet V. MP77-11 HOST CATHELICIDIN EXACERBATES GROUP B STREPTOCOCCUS URINARY TRACT INFECTION The Journal of Urology. 203: e1167. DOI: 10.1097/Ju.0000000000000963.011  0.801
2020 Dillon NA, Nizet V. Old Drugs, New Synergy: Identifying Novel Synergistic Antibiotic Combinations to Combat MDR Bacterial Pathogens The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08718  0.352
2020 Golden GJ, Toledo AG, Cuello H, Nizet V, Esko J. Sulfation of endothelial heparan sulfate mediates Staphylococcus aureus induced hepatotoxicity The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00681  0.306
2020 Choi SM, Christiansen S, Doherty T, DeConde A, Nizet V. Staphylococcus aureus exacerbates impaired airway epithelial barrier seen in AERD The Journal of Allergy and Clinical Immunology. 145. DOI: 10.1016/J.Jaci.2019.12.819  0.304
2019 Ulloa ER, Kousha A, Tsunemoto H, Pogliano J, Licitra C, LiPuma JJ, Sakoulas G, Nizet V, Kumaraswamy M. Azithromycin Exerts Bactericidal Activity and Enhances Innate Immune Mediated Killing of MDR . Infectious Microbes & Diseases. 2: 10-17. PMID 38500653 DOI: 10.1097/im9.0000000000000014  0.345
2019 Shing SR, Ramos AR, Patras KA, Riestra AM, McCabe S, Nizet V, Coady A. The Fungal Pathogen Promotes Bladder Colonization of Group B . Frontiers in Cellular and Infection Microbiology. 9: 437. PMID 31998657 DOI: 10.3389/Fcimb.2019.00437  0.816
2019 Rajput A, Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Knight R, ... Nizet V, et al. Profiling the effect of nafcillin on HA-MRSA D712 using bacteriological and physiological media. Scientific Data. 6: 322. PMID 31848353 DOI: 10.1038/S41597-019-0331-Z  0.808
2019 Valderrama JA, Kulkarni SS, Nizet V, Bier E. A bacterial gene-drive system efficiently edits and inactivates a high copy number antibiotic resistance locus. Nature Communications. 10: 5726. PMID 31844051 DOI: 10.1038/S41467-019-13649-6  0.627
2019 Tsai CM, Riestra AM, Ali SR, Fong JJ, Liu JZ, Hughes G, Varki A, Nizet V. Siglec-14 Enhances NLRP3-Inflammasome Activation in Macrophages. Journal of Innate Immunity. 1-11. PMID 31805552 DOI: 10.1159/000504323  0.803
2019 Ulloa ER, Singh KV, Geriak M, Haddad F, Murray BE, Nizet V, Sakoulas G. Cefazolin and Ertapenem Salvage Therapy Rapidly Clears Persistent Methicillin-Susceptible Staphylococcus aureus Bacteremia. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 31773134 DOI: 10.1093/Cid/Ciz995  0.334
2019 Koo J, Escajadillo T, Zhang L, Nizet V, Lawrence SM. Erythrocyte-Coated Nanoparticles Block Cytotoxic Effects of Group B β-Hemolysin/Cytolysin. Frontiers in Pediatrics. 7: 410. PMID 31737584 DOI: 10.3389/Fped.2019.00410  0.819
2019 Toledo AG, Golden G, Campos AR, Cuello H, Sorrentino J, Lewis N, Varki N, Nizet V, Smith JW, Esko JD. Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis. Nature Communications. 10: 4656. PMID 31604940 DOI: 10.1038/S41467-019-12672-X  0.354
2019 Gao NJ, Al-Bassam MM, Poudel S, Wozniak JM, Gonzalez DJ, Olson J, Zengler K, Nizet V, Valderrama JA. Functional and Proteomic Analysis of Virulence Upon Loss of Its Native Cas9 Nuclease. Frontiers in Microbiology. 10: 1967. PMID 31507572 DOI: 10.3389/Fmicb.2019.01967  0.813
2019 Machado H, Weng LL, Dillon N, Seif Y, Holland M, Pekar JE, Monk JM, Nizet V, Palsson BO, Feist AM. A defined minimal medium for systems analyses of reveals strain-specific metabolic requirements. Applied and Environmental Microbiology. PMID 31471305 DOI: 10.1128/Aem.01773-19  0.779
2019 Cohen Katsenelson K, Stender JD, Kawashima AT, Lordén G, Uchiyama S, Nizet V, Glass CK, Newton AC. PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. Elife. 8. PMID 31408005 DOI: 10.7554/Elife.48609  0.656
2019 Volk CF, Burgdorf S, Edwardson G, Nizet V, Sakoulas G, Rose WE. IL-1β and IL-10 Host Responses in Patients with Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 31365924 DOI: 10.1093/Cid/Ciz686  0.782
2019 Dillon N, Holland M, Tsunemoto H, Hancock B, Cornax I, Pogliano J, Sakoulas G, Nizet V. Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens. Ebiomedicine. PMID 31353294 DOI: 10.1016/J.Ebiom.2019.07.041  0.814
2019 LaRock DL, Sands JS, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN. Inflammasome inhibition blocks cardiac glycoside cell toxicity. The Journal of Biological Chemistry. PMID 31300552 DOI: 10.1074/Jbc.Ra119.008330  0.786
2019 Dahesh S, Wong B, Nizet V, Sakoulas G, Tran TT, Aitken SL. Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin. Antimicrobial Agents and Chemotherapy. 63. PMID 31235559 DOI: 10.1128/Aac.02622-18  0.374
2019 Patras KA, Ha AD, Rooholfada E, Olson J, Ramachandra Rao SP, Lin AE, Nizet V. Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli. Journal of Innate Immunity. 1-15. PMID 31055580 DOI: 10.1159/000499342  0.827
2019 Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. An Experimental Group A Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model. Mbio. 10. PMID 31040243 DOI: 10.1128/Mbio.00693-19  0.306
2019 Poudel S, Tsunemoto H, Meehan M, Szubin R, Olson CA, Lamsa A, Seif Y, Dillon N, Vrbanac A, Sugie J, Dahesh S, Monk JM, Dorrestein PC, Pogliano J, Knight R, ... Nizet V, et al. Characterization of CA-MRSA TCH1516 exposed to nafcillin in bacteriological and physiological media. Scientific Data. 6: 43. PMID 31028276 DOI: 10.1038/S41597-019-0051-4  0.804
2019 Meier A, Chien J, Hobohm L, Patras KA, Nizet V, Corriden R. Inhibition of Human Neutrophil Extracellular Trap (NET) Production by Propofol and Lipid Emulsion. Frontiers in Pharmacology. 10: 323. PMID 31024300 DOI: 10.3389/Fphar.2019.00323  0.81
2019 Ulloa ER, Dillon N, Tsunemoto H, Pogliano J, Sakoulas G, Nizet V. Avibactam Sensitizes Carbapenem-Resistant NDM-1-Producing Klebsiella pneumoniae to Innate Immune Clearance. The Journal of Infectious Diseases. PMID 30923801 DOI: 10.1093/Infdis/Jiz128  0.785
2019 Caffrey AR, Timbrook TT, Ali SR, Nizet V, Sakoulas G. Proton-pump inhibitors do not influence clinical outcomes in patients with bacteremia. Therapeutic Advances in Gastroenterology. 12: 1756284819834273. PMID 30923573 DOI: 10.1177/1756284819834273  0.478
2019 Zhang Q, Chao TC, Patil VS, Qin Y, Tiwari SK, Chiou J, Dobin A, Tsai CM, Li Z, Dang J, Gupta S, Urdahl K, Nizet V, Gingeras TR, Gaulton KJ, et al. The long noncoding RNA regulates inflammatory gene expression. The Embo Journal. PMID 30918008 DOI: 10.15252/Embj.2018100041  0.712
2019 Uchiyama S, Sun J, Fukahori K, Ando N, Wu M, Schwarz F, Siddiqui SS, Varki A, Marth JD, Nizet V. Dual actions of group B capsular sialic acid provide resistance to platelet-mediated antimicrobial killing. Proceedings of the National Academy of Sciences of the United States of America. PMID 30910970 DOI: 10.1073/Pnas.1815572116  0.811
2019 Nerlich A, Lapschies AM, Kohler TP, Cornax I, Eichhorn I, Goldmann O, Krienke P, Bergmann S, Nizet V, Hammerschmidt S, Rohde M, Fulde M. Homophilic protein interactions facilitate bacterial aggregation and IgG-dependent complex formation by the Streptococcus canis M protein SCM. Virulence. PMID 30829556 DOI: 10.1080/21505594.2019.1589362  0.748
2019 Dan JM, Havenar-Daughton C, Kendric K, Al-Kolla R, Kaushik K, Rosales SL, Anderson EL, LaRock CN, Vijayanand P, Seumois G, Layfield D, Cutress RI, Ottensmeier CH, Lindestam Arlehamn CS, Sette A, ... Nizet V, et al. Recurrent group A tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant T cells. Science Translational Medicine. 11. PMID 30728285 DOI: 10.1126/Scitranslmed.Aau3776  0.785
2019 Meier A, Nizet V. Impact of Anesthetics on Human Neutrophil Function. Anesthesia and Analgesia. 128: 569-574. PMID 30507837 DOI: 10.1213/Ane.0000000000003927  0.361
2019 Sakoulas G, Geriak M, Nizet V. Is a Reported Penicillin Allergy Sufficient Grounds to Forgo the Multidimensional Antimicrobial Benefits of β-Lactam Antibiotics? Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 68: 157-164. PMID 29986019 DOI: 10.1093/Cid/Ciy557  0.336
2019 Katsenelson KC, Stender JD, Kawashima AT, Lordén G, Uchiyama S, Nizet V, Glass CK, Newton AC. Author response: PHLPP1 counter-regulates STAT1-mediated inflammatory signaling Elife. DOI: 10.7554/Elife.48609.021  0.606
2019 Tacke R, Sun J, Uchiyama S, Polovina A, Nguyen DG, Nizet V. Protection Against Lethal Multidrug-Resistant Bacterial Infections Using Macrophage Cell Therapy Infectious Microbes & Diseases. 1: 61-69. DOI: 10.1097/im9.0000000000000012  0.818
2019 Rose Ulloa E, Singh KV, Geriak M, Haddad F, Murray BE, Nizet V, Sakoulas G. 217. Combination Salvage Therapy with Cefazolin Plus Ertapenem for Refractory Methicillin-Susceptible Staphylococcus aureus Bacteremia Open Forum Infectious Diseases. 6: S127-S128. DOI: 10.1093/Ofid/Ofz360.292  0.387
2018 Huang YM, Munguia J, Miao Y, Nizet V, McCammon JA. Docking simulation and antibiotic discovery targeting the MlaC protein in Gram-negative bacteria. Chemical Biology & Drug Design. PMID 30570806 DOI: 10.1111/Cbdd.13462  0.33
2018 Escajadillo T, Nizet V. Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection. Toxins. 10. PMID 30562923 DOI: 10.3390/Toxins10120542  0.829
2018 Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, ... Nizet V, et al. Erratum for Schooley et al., "Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection". Antimicrobial Agents and Chemotherapy. 62. PMID 30478181 DOI: 10.1128/Aac.02221-18  0.781
2018 Vrbanac A, Riestra AM, Coady A, Knight R, Nizet V, Patras KA. The murine vaginal microbiota and its perturbation by the human pathogen group B Streptococcus. Bmc Microbiology. 18: 197. PMID 30477439 DOI: 10.1186/S12866-018-1341-2  0.8
2018 Uchiyama S, Dahesh S, Nizet V, Kessler J. IEnhanced Topical Delivery of Non-complexed Molecular Iodine for Methicillin-Resistant Staphylococcus aureus Decolonization. International Journal of Pharmaceutics. PMID 30395958 DOI: 10.1016/J.Ijpharm.2018.11.004  0.691
2018 Riestra AM, Valderrama JA, Patras KA, Booth SD, Quek XY, Tsai CM, Nizet V. Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages. Journal of Innate Immunity. 1-13. PMID 30391945 DOI: 10.1159/000493585  0.801
2018 Kavvas ES, Catoiu E, Mih N, Yurkovich JT, Seif Y, Dillon N, Heckmann D, Anand A, Yang L, Nizet V, Monk JM, Palsson BO. Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance. Nature Communications. 9: 4306. PMID 30333483 DOI: 10.1038/S41467-018-06634-Y  0.775
2018 van Hensbergen VP, Movert E, de Maat V, Lüchtenborg C, Le Breton Y, Lambeau G, Payré C, Henningham A, Nizet V, van Strijp JAG, Brügger B, Carlsson F, McIver KS, van Sorge NM. Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects. Plos Pathogens. 14: e1007348. PMID 30321240 DOI: 10.1371/Journal.Ppat.1007348  0.828
2018 Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD. Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis. Cell Host & Microbe. 24: 500-513.e5. PMID 30308156 DOI: 10.1016/J.Chom.2018.09.011  0.422
2018 Coady A, Ramos AR, Olson J, Nizet V, Patras KA. Tamm-Horsfall protein protects the urinary tract against . Infection and Immunity. PMID 30297523 DOI: 10.1128/Iai.00451-18  0.828
2018 Fong JJ, Tsai CM, Saha S, Nizet V, Varki A, Bui JD. Siglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254166 DOI: 10.1073/Pnas.1804108115  0.764
2018 Alisson-Silva F, Liu JZ, Diaz SL, Deng L, Gareau MG, Marchelletta R, Chen X, Nizet V, Varki N, Barrett KE, Varki A. Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera. Plos Pathogens. 14: e1007133. PMID 29912959 DOI: 10.1371/Journal.Ppat.1007133  0.81
2018 Askarian F, Wagner T, Johannessen M, Nizet V. Staphylococcus aureus modulation of innate immune responses through Toll-like (TLRs), (NOD)-like (NLRs) and C-type lectin (CLRs) receptors. Fems Microbiology Reviews. PMID 29893825 DOI: 10.1093/Femsre/Fuy025  0.754
2018 Patras KA, Derieux J, Al-Bassam MM, Adiletta N, Vrbanac A, Lapek JD, Zengler K, Gonzalez DJ, Nizet V. Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance. The Journal of Infectious Diseases. PMID 29868829 DOI: 10.1093/Infdis/Jiy341  0.817
2018 Soderholm AT, Barnett TC, Korn O, Rivera-Hernandez T, Seymour LM, Schulz BL, Nizet V, Wells CA, Sweet MJ, Walker MJ. Group A M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP. Frontiers in Cellular and Infection Microbiology. 8: 160. PMID 29868516 DOI: 10.3389/Fcimb.2018.00160  0.407
2018 Kumaraswamy M, Collignon S, Do C, Kim J, Nizet V, Friend J. Decontaminating surfaces with atomized disinfectants generated by a novel thickness-mode lithium niobate device. Applied Microbiology and Biotechnology. PMID 29804135 DOI: 10.1007/S00253-018-9088-0  0.718
2018 Jati S, Kundu S, Chakraborty A, Mahata SK, Nizet V, Sen M. Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit. Frontiers in Immunology. 9: 679. PMID 29686674 DOI: 10.3389/Fimmu.2018.00679  0.43
2018 van den Broek MFL, De Boeck I, Claes IJJ, Nizet V, Lebeer S. Multifactorial inhibition of lactobacilli against the respiratory tract pathogen Moraxella catarrhalis. Beneficial Microbes. 9: 429-439. PMID 29633637 DOI: 10.3920/Bm2017.0101  0.386
2018 Monogue ML, Sakoulas G, Nizet V, Nicolau DP. Humanized Exposures of a β-Lactam-β-Lactamase Inhibitor, Tazobactam, versus Non-β-Lactam-β-Lactamase Inhibitor, Avibactam, with or without Colistin, against Acinetobacter baumannii in Murine Thigh and Lung Infection Models. Pharmacology. 101: 255-261. PMID 29533955 DOI: 10.1159/000486445  0.337
2018 Patras KA, Nizet V. Group B Streptococcal Maternal Colonization and Neonatal Disease: Molecular Mechanisms and Preventative Approaches. Frontiers in Pediatrics. 6: 27. PMID 29520354 DOI: 10.3389/Fped.2018.00027  0.752
2018 Askarian F, Lapek JD, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M. Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Frontiers in Microbiology. 9: 262. PMID 29515544 DOI: 10.3389/Fmicb.2018.00262  0.822
2018 Gupta N, Liu R, Shin S, Sinha R, Pogliano J, Pogliano K, Griffin JH, Nizet V, Corriden R. SCH79797 improves outcomes in experimental bacterial pneumonia by boosting neutrophil killing and direct antibiotic activity. The Journal of Antimicrobial Chemotherapy. PMID 29514266 DOI: 10.1093/Jac/Dky033  0.81
2018 Haripriyan J, Omanakuttan A, Menon ND, Vanuopadath M, Nair SS, Corriden R, Nair BG, Nizet V, Kumar GB. Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa. Scientific Reports. 8: 3437. PMID 29467483 DOI: 10.1038/S41598-018-19771-7  0.753
2018 Lawrence SM, Corriden R, Nizet V. The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis. Microbiology and Molecular Biology Reviews : Mmbr. 82. PMID 29436479 DOI: 10.1128/Mmbr.00057-17  0.713
2018 Chen Y, Chen M, Zhang Y, Lee JH, Escajadillo T, Gong H, Fang RH, Gao W, Nizet V, Zhang L. Broad-Spectrum Neutralization of Pore-Forming Toxins with Human Erythrocyte Membrane-Coated Nanosponges. Advanced Healthcare Materials. PMID 29436150 DOI: 10.1002/Adhm.201701366  0.821
2018 Liu JZ, Ali SR, Bier E, Nizet V. Innate Immune Interactions between Bacillus anthracis and Host Neutrophils. Frontiers in Cellular and Infection Microbiology. 8: 2. PMID 29404280 DOI: 10.3389/Fcimb.2018.00002  0.834
2018 Gupta N, Sinha R, Krasnodembskaya A, Xu X, Nizet V, Matthay MA, Griffin JH. The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia. Stem Cells (Dayton, Ohio). PMID 29396891 DOI: 10.1002/Stem.2796  0.337
2018 Choe D, Szubin R, Dahesh S, Cho S, Nizet V, Palsson B, Cho BK. Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance. Scientific Reports. 8: 2215. PMID 29396540 DOI: 10.1038/S41598-018-20661-1  0.513
2018 Henningham A, Davies MR, Uchiyama S, van Sorge NM, Lund S, Chen KT, Walker MJ, Cole JN, Nizet V. Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A Streptococcus. Mbio. 9. PMID 29382733 DOI: 10.1128/Mbio.02294-17  0.823
2018 Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V. Listeria monocytogenes Endocarditis: Case Report, Review of the Literature, and Laboratory Evaluation of Potential Novel Antibiotic Synergies. International Journal of Antimicrobial Agents. PMID 29337066 DOI: 10.1016/J.Ijantimicag.2017.12.032  0.758
2018 Valderrama JA, Nizet V. Group A Streptococcus encounters with host macrophages. Future Microbiology. 13: 119-134. PMID 29226710 DOI: 10.2217/Fmb-2017-0142  0.699
2018 Ulloa ER, Dillon N, Sakoulas G, Nizet V. 2390. Avibactam Sensitizes NDM Klebsiella pneumoniae to Innate Immune Killing by Human Cathelicidin LL-37, Serum, Neutrophils, and Platelets Open Forum Infectious Diseases. 5: S712-S713. DOI: 10.1093/Ofid/Ofy210.2043  0.752
2018 Chen Y, Chen M, Zhang Y, Lee JH, Escajadillo T, Gong H, Fang RH, Gao W, Nizet V, Zhang L. Antivirulence Therapy: Broad-Spectrum Neutralization of Pore-Forming Toxins with Human Erythrocyte Membrane-Coated Nanosponges (Adv. Healthcare Mater. 13/2018) Advanced Healthcare Materials. 7: 1870049. DOI: 10.1002/Adhm.201870049  0.77
2017 Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD. Recurrent infection progressively disables host protection against intestinal inflammation. Science (New York, N.Y.). 358. PMID 29269445 DOI: 10.1126/Science.Aao5610  0.388
2017 Catteau L, Reichmann NT, Olson J, Pinho MG, Nizet V, Van Bambeke F, Quetin-Leclercq J. Synergy between Ursolic and Oleanolic Acids from Vitellaria paradoxa Leaf Extract and β-Lactams against Methicillin-Resistant Staphylococcus aureus: In Vitro and In Vivo Activity and Underlying Mechanisms. Molecules (Basel, Switzerland). 22. PMID 29258194 DOI: 10.3390/Molecules22122245  0.378
2017 Sakoulas G, Kumaraswamy M, Kousha A, Nizet V. Interaction of Antibiotics with Innate Host Defense Factors against Salmonella enterica Serotype Newport. Msphere. 2. PMID 29242830 DOI: 10.1128/mSphere.00410-17  0.829
2017 Mascuch SJ, Boudreau PD, Carland TM, Pierce NT, Olson J, Hensler ME, Choi H, Campanale J, Hamdoun A, Nizet V, Gerwick WH, Gaasterland T, Gerwick L. Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway. Journal of Natural Products. PMID 29215273 DOI: 10.1021/Acs.Jnatprod.7B00734  0.71
2017 Reynolds KA, Luhavaya H, Li J, Dahesh S, Nizet V, Yamanaka K, Moore BS. Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster. The Journal of Antibiotics. PMID 29184121 DOI: 10.1038/Ja.2017.146  0.356
2017 Zhang Y, Gao W, Chen Y, Escajadillo T, Ungerleider JL, Fang RH, Christman KL, Nizet V, Zhang L. Self-Assembled Colloidal Gel Using Cell Membrane-Coated Nanosponges as Building Blocks. Acs Nano. PMID 29116753 DOI: 10.1021/Acsnano.7B06968  0.779
2017 Andreoni F, Ugolini F, Keller N, Neff A, Nizet V, Hollands A, Marques Maggio E, Zinkernagel AS, Schuepbach RA. Immunoglobulin attenuates streptokinase-mediated virulence in Streptococcus dysgalactiae subsp. equisimilis necrotizing fasciitis. The Journal of Infectious Diseases. PMID 29099935 DOI: 10.1093/Infdis/Jix560  0.806
2017 Thamphiwatana S, Angsantikul P, Escajadillo T, Zhang Q, Olson J, Luk BT, Zhang S, Fang RH, Gao W, Nizet V, Zhang L. Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management. Proceedings of the National Academy of Sciences of the United States of America. 114: 11488-11493. PMID 29073076 DOI: 10.1073/Pnas.1714267114  0.796
2017 Mesci P, Macia A, LaRock CN, Tejwani L, Fernandes IR, Suarez NA, Zanotto PMA, Beltrão-Braga PCB, Nizet V, Muotri AR. Modeling neuro-immune interactions during Zika virus infection. Human Molecular Genetics. PMID 29048558 DOI: 10.1093/Hmg/Ddx382  0.727
2017 Guichard A, Jain P, Moayeri M, Schwartz R, Chin S, Zhu L, Cruz-Moreno B, Liu JZ, Aguilar B, Hollands A, Leppla SH, Nizet V, Bier E. Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport. Plos Pathogens. 13: e1006603. PMID 28945820 DOI: 10.1371/Journal.Ppat.1006603  0.799
2017 Sun J, Lei L, Tsai CM, Wang Y, Shi Y, Ouyang M, Lu S, Seong J, Kim TJ, Wang P, Huang M, Xu X, Nizet V, Chien S, Wang Y. Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions. Nature Communications. 8: 477. PMID 28883531 DOI: 10.1038/S41467-017-00569-6  0.677
2017 Munguia J, LaRock DL, Tsunemoto H, Olson J, Cornax I, Pogliano J, Nizet V. The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance. Journal of Molecular Medicine (Berlin, Germany). PMID 28844103 DOI: 10.1007/S00109-017-1579-4  0.831
2017 Patras KA, Coady A, Olson J, Ali SR, RamachandraRao SP, Kumar S, Varki A, Nizet V. Tamm-Horsfall glycoprotein engages human Siglec-9 to modulate neutrophil activation in the urinary tract. Immunology and Cell Biology. PMID 28829050 DOI: 10.1038/Icb.2017.63  0.831
2017 Schooley RT, Biswas B, Gill JJ, Hernandez-Morales A, Lancaster J, Lessor L, Barr JJ, Reed SL, Rohwer F, Benler S, Segall AM, Taplitz R, Smith DM, Kerr K, Kumaraswamy M, ... Nizet V, et al. Development and use of personalized bacteriophage-based therapeutic cocktails to treat a patient with a disseminated resistant Acinetobacter baumannii infection. Antimicrobial Agents and Chemotherapy. PMID 28807909 DOI: 10.1128/Aac.00954-17  0.814
2017 Valderrama JA, Riestra AM, Gao NJ, LaRock CN, Gupta N, Ali SR, Hoffman HM, Ghosh P, Nizet V. Group A streptococcal M protein activates the NLRP3 inflammasome. Nature Microbiology. PMID 28784982 DOI: 10.1038/S41564-017-0005-6  0.807
2017 Escajadillo T, Olson J, Luk BT, Zhang L, Nizet V. A Red Blood Cell Membrane-Camouflaged Nanoparticle Counteracts Streptolysin O-Mediated Virulence Phenotypes of Invasive Group A Streptococcus. Frontiers in Pharmacology. 8: 477. PMID 28769806 DOI: 10.3389/Fphar.2017.00477  0.838
2017 Severino P, Ariga SK, Barbeiro HV, de Lima TM, de Paula Silva E, Barbeiro DF, Machado MCC, Nizet V, da Silva FP. Cathelicidin-deficient mice exhibit increased survival and upregulation of key inflammatory response genes following cecal ligation and puncture. Journal of Molecular Medicine (Berlin, Germany). PMID 28623379 DOI: 10.1007/S00109-017-1555-Z  0.37
2017 Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L. Human milk oligosaccharides inhibit growth of group B Streptococcus. The Journal of Biological Chemistry. PMID 28416607 DOI: 10.1074/Jbc.M117.789974  0.831
2017 Lizcano A, Secundino I, Döhrmann S, Corriden R, Rohena C, Diaz S, Ghosh P, Deng L, Nizet V, Varki A. Erythrocyte sialoglycoproteins engage Siglec-9 on neutrophils to suppress activation. Blood. PMID 28416510 DOI: 10.1182/Blood-2016-11-751636  0.811
2017 Lawrence SM, Corriden R, Nizet V. Age-Appropriate Functions and Dysfunctions of the Neonatal Neutrophil. Frontiers in Pediatrics. 5: 23. PMID 28293548 DOI: 10.3389/Fped.2017.00023  0.72
2017 Munguia J, Nizet V. Pharmacological Targeting of the Host-Pathogen Interaction: Alternatives to Classical Antibiotics to Combat Drug-Resistant Superbugs. Trends in Pharmacological Sciences. PMID 28283200 DOI: 10.1016/J.Tips.2017.02.003  0.43
2017 Döhrmann S, LaRock CN, Anderson EL, Cole JN, Ryali B, Stewart C, Nonejuie P, Pogliano J, Corriden R, Ghosh P, Nizet V. Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones. Scientific Reports. 7: 43039. PMID 28220899 DOI: 10.1038/Srep43039  0.818
2017 Okerblom JJ, Schwarz F, Olson J, Fletes W, Ali SR, Martin PT, Glass CK, Nizet V, Varki A. Loss of CMAH during Human Evolution Primed the Monocyte-Macrophage Lineage toward a More Inflammatory and Phagocytic State. Journal of Immunology (Baltimore, Md. : 1950). PMID 28148732 DOI: 10.4049/Jimmunol.1601471  0.675
2017 De Oliveira DM, Hartley-Tassell L, Everest-Dass A, Day CJ, Dabbs RA, Ve T, Kobe B, Nizet V, Packer NH, Walker MJ, Jennings MP, Sanderson-Smith ML. Blood Group Antigen Recognition via the Group A Streptococcal M Protein Mediates Host Colonization. Mbio. 8. PMID 28119471 DOI: 10.1128/Mbio.02237-16  0.371
2017 Schwarz F, Landig CS, Siddiqui S, Secundino I, Olson J, Varki N, Nizet V, Varki A. Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. The Embo Journal. PMID 28100677 DOI: 10.15252/Embj.201695581  0.564
2017 van Wijk XM, Döhrmann S, Hallström BM, Li S, Voldborg BG, Meng BX, McKee KK, van Kuppevelt TH, Yurchenco PD, Palsson BO, Lewis NE, Nizet V, Esko JD. Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion. Mbio. 8. PMID 28074024 DOI: 10.1128/Mbio.02128-16  0.813
2016 LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AAB, Cooper MA, Hoffman HM, Nizet V. IL-1β is an innate immune sensor of microbial proteolysis. Science Immunology. 1: eaah3539. PMID 28783696 DOI: 10.1126/sciimmunol.aah3539  0.791
2016 LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AA, Cooper MA, Hoffman HM, Nizet V. IL-1β is an innate immune sensor of microbial proteolysis. Science Immunology. 1. PMID 28331908 DOI: 10.1126/Sciimmunol.Aah3539  0.791
2016 Coady A, Nizet V. SAMP-ending down sepsis. Annals of Translational Medicine. 4: 509. PMID 28149871 DOI: 10.21037/Atm.2016.11.31  0.697
2016 Sorg RA, Lin L, van Doorn GS, Sorg M, Olson J, Nizet V, Veening JW. Collective Resistance in Microbial Communities by Intracellular Antibiotic Deactivation. Plos Biology. 14: e2000631. PMID 28027306 DOI: 10.1371/Journal.Pbio.2000631  0.738
2016 Flores R, Döhrmann S, Schaal C, Hakkim A, Nizet V, Corriden R. The Selective Estrogen Receptor Modulator Raloxifene Inhibits Neutrophil Extracellular Trap Formation. Frontiers in Immunology. 7: 566. PMID 28003814 DOI: 10.3389/Fimmu.2016.00566  0.803
2016 Sakoulas G, Rose W, Berti A, Olson J, Mungia J, Nonejuie P, Sakoulas E, Rybak MJ, Pogliano J, Nizet V. Classical β-lactamase Inhibitors Potentiate the Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus and Colistin Against Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy. PMID 27872080 DOI: 10.1128/Aac.01745-16  0.418
2016 Storisteanu DM, Pocock JM, Cowburn AS, Juss JK, Nadesalingam A, Nizet V, Chilvers ER. Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens. American Journal of Respiratory Cell and Molecular Biology. PMID 27854516 DOI: 10.1165/Rcmb.2016-0193Ps  0.426
2016 Askarian F, Uchiyama S, Valderrama JA, Ajayi C, Sollid JU, van Sorge NM, Nizet V, van Strijp JA, Johannessen M. Serine-aspartate-repeat protein D Increases Staphylococcus aureus Virulence and Survival in Blood. Infection and Immunity. PMID 27795358 DOI: 10.1128/Iai.00559-16  0.828
2016 Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P. Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nature Microbiology. 1: 16155. PMID 27595425 DOI: 10.1038/Nmicrobiol.2016.155  0.301
2016 Hentrich K, Löfling J, Pathak A, Nizet V, Varki A, Henriques-Normark B. Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR. Cell Host & Microbe. PMID 27593514 DOI: 10.1016/J.Chom.2016.07.019  0.562
2016 Sakoulas G, Olson J, Yim J, Singh NB, Kumaraswamy M, Quach DT, Rybak MJ, Pogliano J, Nizet V. Cefazolin and Ertapenem: A Synergistic Combination Used to Clear Persistent Staphylococcus aureus Bacteremia. Antimicrobial Agents and Chemotherapy. PMID 27572414 DOI: 10.1128/Aac.01192-16  0.733
2016 Stewart CM, Buffalo CZ, Valderrama JA, Henningham A, Cole JN, Nizet V, Ghosh P. Coiled-coil destabilizing residues in the group A Streptococcus M1 protein are required for functional interaction. Proceedings of the National Academy of Sciences of the United States of America. PMID 27512043 DOI: 10.1073/Pnas.1606160113  0.71
2016 Döhrmann S, Cole JN, Nizet V. Conquering Neutrophils. Plos Pathogens. 12: e1005682. PMID 27467389 DOI: 10.1371/journal.ppat.1005682  0.786
2016 Yamaguchi M, Hirose Y, Nakata M, Uchiyama S, Yamaguchi Y, Goto K, Sumitomo T, Lewis AL, Kawabata S, Nizet V. Evolutionary inactivation of a sialidase in group B Streptococcus. Scientific Reports. 6: 28852. PMID 27352769 DOI: 10.1038/Srep28852  0.814
2016 Rivera-Hernandez T, Pandey M, Henningham A, Cole J, Choudhury B, Cork AJ, Gillen CM, Ghaffar KA, West NP, Silvestri G, Good MF, Moyle PM, Toth I, Nizet V, Batzloff MR, et al. Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models. Mbio. 7. PMID 27302756 DOI: 10.1128/Mbio.00618-16  0.596
2016 Bosi E, Monk JM, Aziz RK, Fondi M, Nizet V, Palsson BØ. Comparative genome-scale modelling of Staphylococcus aureus strains identifies strain-specific metabolic capabilities linked to pathogenicity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27286824 DOI: 10.1073/Pnas.1523199113  0.506
2016 Carey AJ, Weinberg JB, Dawid SR, Venturini C, Lam AK, Nizet V, Caparon MG, Walker MJ, Watson ME, Ulett GC. Interleukin-17A Contributes to the Control of Streptococcus pyogenes Colonization and Inflammation of the Female Genital Tract. Scientific Reports. 6: 26836. PMID 27241677 DOI: 10.1038/Srep26836  0.326
2016 Le J, Dam Q, Schweizer M, Thienphrapa W, Nizet V, Sakoulas G. Effects of vancomycin versus nafcillin in enhancing killing of methicillin-susceptible Staphylococcus aureus causing bacteremia by human cathelicidin LL-37. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. PMID 27234592 DOI: 10.1007/S10096-016-2682-0  0.43
2016 Hollands A, Corriden R, Gysler G, Dahesh S, Olson J, Ali SR, Kunkel MT, Lin AE, Forli S, Newton AC, Kumar GB, Nair BG, Perry JJ, Nizet V. Natural product anacardic acid from cashew nut shells stimulates neutrophil extracellular trap production and bactericidal activity. The Journal of Biological Chemistry. PMID 27226531 DOI: 10.1074/Jbc.M115.695866  0.799
2016 Lin L, Kim J, Chen H, Kowalski R, Nizet V. Component Analysis of Multi-Purpose Contact Lens Solutions to Enhance Activity Against Pseudomonas aeruginosa and Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. PMID 27139484 DOI: 10.1128/Aac.00644-16  0.696
2016 Völlger L, Akong-Moore K, Cox L, Goldmann O, Wang Y, Schäfer ST, Naim HY, Nizet V, von Köckritz-Blickwede M. Iron chelating agent desferrioxamine stimulates formation of neutrophil extracellular traps (NETs) in human blood-derived neutrophils. Bioscience Reports. PMID 27129288 DOI: 10.1042/Bsr20160031  0.805
2016 Huang YM, Miao Y, Munguia J, Lin L, Nizet V, McCammon JA. Molecular dynamic study of MlaC protein in Gram-negative bacteria: conformational flexibility, solvent effect and protein-phospholipid binding. Protein Science : a Publication of the Protein Society. 25: 1430-7. PMID 27111825 DOI: 10.1002/Pro.2939  0.686
2016 von Köckritz-Blickwede M, Blodkamp S, Nizet V. Interaction of Bacterial Exotoxins with Neutrophil Extracellular Traps: Impact for the Infected Host. Frontiers in Microbiology. 7: 402. PMID 27064864 DOI: 10.3389/Fmicb.2016.00402  0.412
2016 Cole JN, Nizet V. Bacterial Evasion of Host Antimicrobial Peptide Defenses. Microbiology Spectrum. 4. PMID 26999396 DOI: 10.1128/Microbiolspec.Vmbf-0006-2015  0.672
2016 Kumaraswamy M, Lin L, Olson J, Sun CF, Nonejuie P, Corriden R, Döhrmann S, Ali SR, Amaro D, Rohde M, Pogliano J, Sakoulas G, Nizet V. Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. The Journal of Antimicrobial Chemotherapy. PMID 26832758 DOI: 10.1093/Jac/Dkv487  0.803
2016 Lizcano A, Secundino I, Dohrmann S, Corriden R, Deng L, Diaz S, Nizet V, Varki AP. Erythrocyte Sialoglycoproteins Engage Siglec-9 to Maintain Neutrophil Quiescence in the Bloodstream Blood. 128: 1022-1022. DOI: 10.1182/Blood.V128.22.1022.1022  0.811
2016 Tor Y, Volonterio A, Sganappa A, Bellucci M, Nizet V. Multicomponent Domino Synthesis and Antibacterial Activity of Neomycin–Sugar Conjugates Synthesis. 48: 4443-4450. DOI: 10.1055/S-0035-1562727  0.347
2015 Kolar SL, Kyme P, Tseng CW, Soliman A, Kaplan A, Liang J, Nizet V, Jiang D, Murali R, Arditi M, Underhill DM, Liu GY. Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan. Cell Host & Microbe. 18: 694-704. PMID 26651945 DOI: 10.1016/J.Chom.2015.11.001  0.554
2015 Uchiyama S, Döhrmann S, Timmer AM, Dixit N, Ghochani M, Bhandari T, Timmer JC, Sprague K, Bubeck-Wardenburg J, Simon SI, Nizet V. Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus. Frontiers in Immunology. 6: 581. PMID 26635795 DOI: 10.3389/Fimmu.2015.00581  0.815
2015 Berti AD, Theisen E, Sauer JD, Nonejuie P, Olson J, Pogliano J, Sakoulas G, Nizet V, Proctor RA, Rose WE. Penicillin binding protein 1 is important in the compensatory response of Staphylococcus aureus to daptomycin-induced membrane damage and is a potential target for β-lactam-daptomycin synergy. Antimicrobial Agents and Chemotherapy. PMID 26525797 DOI: 10.1128/Aac.02071-15  0.353
2015 LaRock CN, Nizet V. Inflammasome/IL-1β Responses to Streptococcal Pathogens. Frontiers in Immunology. 6: 518. PMID 26500655 DOI: 10.3389/Fimmu.2015.00518  0.744
2015 LaRock CN, Döhrmann S, Todd J, Corriden R, Olson J, Johannssen T, Lepenies B, Gallo RL, Ghosh P, Nizet V. Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing. Cell Host & Microbe. 18: 471-7. PMID 26468750 DOI: 10.1016/J.Chom.2015.09.004  0.825
2015 Fong JJ, Sreedhara K, Deng L, Varki NM, Angata T, Liu Q, Nizet V, Varki A. Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14. The Embo Journal. PMID 26459514 DOI: 10.15252/Embj.201591407  0.515
2015 Corriden R, Hollands A, Olson J, Derieux J, Lopez J, Chang JT, Gonzalez DJ, Nizet V. Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide. Nature Communications. 6: 8369. PMID 26458291 DOI: 10.1038/Ncomms9369  0.82
2015 Barnett TC, Cole JN, Rivera-Hernandez T, Henningham A, Paton JC, Nizet V, Walker MJ. Streptococcal toxins: role in pathogenesis and disease. Cellular Microbiology. PMID 26433203 DOI: 10.1111/Cmi.12531  0.652
2015 Secundino I, Lizcano A, Roupé KM, Wang X, Cole JN, Olson J, Ali SR, Dahesh S, Amayreh LK, Henningham A, Varki A, Nizet V. Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation. Journal of Molecular Medicine (Berlin, Germany). PMID 26411873 DOI: 10.1007/S00109-015-1341-8  0.773
2015 Grimsey NJ, Aguilar B, Smith TH, Le P, Soohoo AL, Puthenveedu MA, Nizet V, Trejo J. Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes. The Journal of Cell Biology. PMID 26391660 DOI: 10.1083/Jcb.201504007  0.615
2015 Pence MA, Haste NM, Meharena HS, Olson J, Gallo RL, Nizet V, Kristian SA. Beta-Lactamase Repressor BlaI Modulates Staphylococcus aureus Cathelicidin Antimicrobial Peptide Resistance and Virulence. Plos One. 10: e0136605. PMID 26305782 DOI: 10.1371/Journal.Pone.0136605  0.822
2015 Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens. Ebiomedicine. 2: 690-8. PMID 26288841 DOI: 10.1016/J.Ebiom.2015.05.021  0.827
2015 Sakoulas G, Kumaraswamy M, Nonejuie P, Werth BJ, Rybak MJ, Pogliano J, Rice LB, Nizet V. Differential Effects of Penicillin Binding Protein Deletion on the Susceptibility of Enterococcus faecium to Cationic Peptide Antibiotics. Antimicrobial Agents and Chemotherapy. 59: 6132-9. PMID 26195528 DOI: 10.1128/Aac.00486-15  0.762
2015 Nizet V. Stopping superbugs, maintaining the microbiota. Science Translational Medicine. 7: 295ed8. PMID 26157027 DOI: 10.1126/Scitranslmed.Aab2373  0.354
2015 Xu D, Olson J, Cole JN, van Wijk XM, Brinkmann V, Zychlinsky A, Nizet V, Esko JD, Chang YC. Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. Infection and Immunity. 83: 3648-56. PMID 26150541 DOI: 10.1128/Iai.00545-15  0.72
2015 Holden JK, Kang S, Beasley FC, Cinelli MA, Li H, Roy SG, Dejam D, Edinger AL, Nizet V, Silverman RB, Poulos TL. Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus. Chemistry & Biology. 22: 785-92. PMID 26091171 DOI: 10.1016/J.Chembiol.2015.05.013  0.778
2015 Hindler JA, Wong-Beringer A, Charlton CL, Miller SA, Kelesidis T, Carvalho M, Sakoulas G, Nonejuie P, Pogliano J, Nizet V, Humphries R. In Vitro Activity of Daptomycin in Combination with β-Lactams, Gentamicin, Rifampin, and Tigecycline against Daptomycin-Nonsusceptible Enterococci. Antimicrobial Agents and Chemotherapy. 59: 4279-88. PMID 25963982 DOI: 10.1128/Aac.05077-14  0.351
2015 Kristian SA, Hwang JH, Hall B, Leire E, Iacomini J, Old R, Galili U, Roberts C, Mullis KB, Westby M, Nizet V. Retargeting pre-existing human antibodies to a bacterial pathogen with an alpha-Gal conjugated aptamer. Journal of Molecular Medicine (Berlin, Germany). 93: 619-31. PMID 25940316 DOI: 10.1007/S00109-015-1280-4  0.812
2015 Lin AE, Beasley FC, Olson J, Keller N, Shalwitz RA, Hannan TJ, Hultgren SJ, Nizet V. Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection. Plos Pathogens. 11: e1004818. PMID 25927232 DOI: 10.1371/Journal.Ppat.1004818  0.826
2015 Harbut MB, Vilchèze C, Luo X, Hensler ME, Guo H, Yang B, Chatterjee AK, Nizet V, Jacobs WR, Schultz PG, Wang F. Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 112: 4453-8. PMID 25831516 DOI: 10.1073/Pnas.1504022112  0.748
2015 McEachern EK, Hwang JH, Sladewski KM, Nicatia S, Dewitz C, Mathew DP, Nizet V, Alexander LE. Analysis of the effects of cigarette smoke on staphylococcal virulence phenotypes. Infection and Immunity. 83: 2443-52. PMID 25824841 DOI: 10.1128/Iai.00303-15  0.803
2015 Lin AE, Beasley FC, Keller N, Hollands A, Urbano R, Troemel ER, Hoffman HM, Nizet V. A group A Streptococcus ADP-ribosyltransferase toxin stimulates a protective interleukin 1β-dependent macrophage immune response. Mbio. 6: e00133. PMID 25759502 DOI: 10.1128/Mbio.00133-15  0.82
2015 Shalova IN, Lim JY, Chittezhath M, Zinkernagel AS, Beasley F, Hernández-Jiménez E, Toledano V, Cubillos-Zapata C, Rapisarda A, Chen J, Duan K, Yang H, Poidinger M, Melillo G, Nizet V, et al. Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α. Immunity. 42: 484-98. PMID 25746953 DOI: 10.1016/J.Immuni.2015.02.001  0.815
2015 Berti AD, Baines SL, Howden BP, Sakoulas G, Nizet V, Proctor RA, Rose WE. Heterogeneity of genetic pathways toward daptomycin nonsusceptibility in Staphylococcus aureus determined by adjunctive antibiotics. Antimicrobial Agents and Chemotherapy. 59: 2799-806. PMID 25733508 DOI: 10.1128/Aac.04990-14  0.324
2015 Matak P, Heinis M, Mathieu JR, Corriden R, Cuvellier S, Delga S, Mounier R, Rouquette A, Raymond J, Lamarque D, Emile JF, Nizet V, Touati E, Peyssonnaux C. Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis. Journal of Immunology (Baltimore, Md. : 1950). 194: 3259-66. PMID 25710915 DOI: 10.4049/Jimmunol.1401260  0.792
2015 LaRock CN, Nizet V. Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens. Biochimica Et Biophysica Acta. 1848: 3047-54. PMID 25701232 DOI: 10.1016/J.Bbamem.2015.02.010  0.763
2015 Bier E, Nizet V. Hedgehog: linking uracil to innate defense. Cell Host & Microbe. 17: 146-8. PMID 25674980 DOI: 10.1016/J.Chom.2015.01.010  0.346
2015 Henningham A, Döhrmann S, Nizet V, Cole JN. Mechanisms of group A Streptococcus resistance to reactive oxygen species. Fems Microbiology Reviews. 39: 488-508. PMID 25670736 DOI: 10.1093/Femsre/Fuu009  0.818
2015 Patel V, Carrion K, Hollands A, Hinton A, Gallegos T, Dyo J, Sasik R, Leire E, Hardiman G, Mohamed SA, Nigam S, King CC, Nizet V, Nigam V. The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-κB signaling, and inflammatory gene expression in human aortic valve cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1859-68. PMID 25630970 DOI: 10.1096/Fj.14-257808  0.773
2015 Sakoulas G, Nonejuie P, Kullar R, Pogliano J, Rybak MJ, Nizet V. Examining the use of ceftaroline in the treatment of Streptococcus pneumoniae meningitis with reference to human cathelicidin LL-37. Antimicrobial Agents and Chemotherapy. 59: 2428-31. PMID 25605351 DOI: 10.1128/Aac.04965-14  0.345
2015 Wilkinson DS, Jariwala JS, Anderson E, Mitra K, Meisenhelder J, Chang JT, Ideker T, Hunter T, Nizet V, Dillin A, Hansen M. Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy. Molecular Cell. 57: 55-68. PMID 25544559 DOI: 10.1016/J.Molcel.2014.11.019  0.782
2015 Kang S, Watanabe M, Jacobs JC, Yamaguchi M, Dahesh S, Nizet V, Leyh TS, Silverman RB. Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability. European Journal of Medicinal Chemistry. 90: 448-61. PMID 25461893 DOI: 10.1016/J.Ejmech.2014.11.040  0.616
2015 Quach DT, Sakoulas G, Nizet V, Pogliano J, Pogliano K. Bacterial Cytological Profiling (BCP) as a Rapid and Accurate Antimicrobial Susceptibility Testing Method for Staphylococcus aureus Ebiomedicine. DOI: 10.1016/J.Ebiom.2016.01.020  0.407
2015 Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens Ebiomedicine. DOI: 10.1016/j.ebiom.2015.05.021  0.814
2014 Gonzalez DJ, Corriden R, Akong-Moore K, Olson J, Dorrestein PC, Nizet V. N-terminal ArgD peptides from the classical Staphylococcus aureus Agr system have cytotoxic and proinflammatory activities. Chemistry & Biology. 21: 1457-62. PMID 25457179 DOI: 10.1016/J.Chembiol.2014.09.015  0.799
2014 Palazon A, Goldrath AW, Nizet V, Johnson RS. HIF transcription factors, inflammation, and immunity. Immunity. 41: 518-28. PMID 25367569 DOI: 10.1016/J.Immuni.2014.09.008  0.336
2014 Henningham A, Yamaguchi M, Aziz RK, Kuipers K, Buffalo CZ, Dahesh S, Choudhury B, Van Vleet J, Yamaguchi Y, Seymour LM, Ben Zakour NL, He L, Smith HV, Grimwood K, Beatson SA, ... ... Nizet V, et al. Mutual exclusivity of hyaluronan and hyaluronidase in invasive group A Streptococcus. The Journal of Biological Chemistry. 289: 32303-15. PMID 25266727 DOI: 10.1074/Jbc.M114.602847  0.808
2014 Neumann A, Berends ET, Nerlich A, Molhoek EM, Gallo RL, Meerloo T, Nizet V, Naim HY, von Köckritz-Blickwede M. The antimicrobial peptide LL-37 facilitates the formation of neutrophil extracellular traps. The Biochemical Journal. 464: 3-11. PMID 25181554 DOI: 10.1042/Bj20140778  0.797
2014 Vega VL, Crotty Alexander LE, Charles W, Hwang JH, Nizet V, De Maio A. Activation of the stress response in macrophages alters the M1/M2 balance by enhancing bacterial killing and IL-10 expression. Journal of Molecular Medicine (Berlin, Germany). 92: 1305-17. PMID 25163764 DOI: 10.1007/S00109-014-1201-Y  0.339
2014 Bhandari T, Nizet V. Hypoxia-Inducible Factor (HIF) as a Pharmacological Target for Prevention and Treatment of Infectious Diseases. Infectious Diseases and Therapy. 3: 159-74. PMID 25134687 DOI: 10.1007/S40121-014-0030-1  0.813
2014 Schommer NN, Muto J, Nizet V, Gallo RL. Hyaluronan breakdown contributes to immune defense against group A Streptococcus. The Journal of Biological Chemistry. 289: 26914-21. PMID 25122767 DOI: 10.1074/Jbc.M114.575621  0.368
2014 Guichard A, Nizet V, Bier E. RAB11-mediated trafficking in host-pathogen interactions. Nature Reviews. Microbiology. 12: 624-34. PMID 25118884 DOI: 10.1038/Nrmicro3325  0.414
2014 Fair RJ, McCoy LS, Hensler ME, Aguilar B, Nizet V, Tor Y. Singly modified amikacin and tobramycin derivatives show increased rRNA A-site binding and higher potency against resistant bacteria. Chemmedchem. 9: 2164-71. PMID 25055981 DOI: 10.1002/Cmdc.201402175  0.793
2014 Döhrmann S, Anik S, Olson J, Anderson EL, Etesami N, No H, Snipper J, Nizet V, Okumura CY. Role for streptococcal collagen-like protein 1 in M1T1 group A Streptococcus resistance to neutrophil extracellular traps. Infection and Immunity. 82: 4011-20. PMID 25024366 DOI: 10.1128/Iai.01921-14  0.842
2014 Sakoulas G, Moise PA, Casapao AM, Nonejuie P, Olson J, Okumura CY, Rybak MJ, Kullar R, Dhand A, Rose WE, Goff DA, Bressler AM, Lee Y, Pogliano J, Johns S, ... ... Nizet V, et al. Antimicrobial salvage therapy for persistent staphylococcal bacteremia using daptomycin plus ceftaroline. Clinical Therapeutics. 36: 1317-33. PMID 25017183 DOI: 10.1016/J.Clinthera.2014.05.061  0.749
2014 Neumann A, Völlger L, Berends ET, Molhoek EM, Stapels DA, Midon M, Friães A, Pingoud A, Rooijakkers SH, Gallo RL, Mörgelin M, Nizet V, Naim HY, von Köckritz-Blickwede M. Novel role of the antimicrobial peptide LL-37 in the protection of neutrophil extracellular traps against degradation by bacterial nucleases. Journal of Innate Immunity. 6: 860-8. PMID 25012862 DOI: 10.1159/000363699  0.818
2014 Okumura CY, Nizet V. Subterfuge and sabotage: evasion of host innate defenses by invasive gram-positive bacterial pathogens. Annual Review of Microbiology. 68: 439-58. PMID 25002085 DOI: 10.1146/Annurev-Micro-092412-155711  0.802
2014 Chang YC, Nizet V. The interplay between Siglecs and sialylated pathogens. Glycobiology. 24: 818-25. PMID 24996821 DOI: 10.1093/Glycob/Cwu067  0.596
2014 van Sorge NM, Cole JN, Kuipers K, Henningham A, Aziz RK, Kasirer-Friede A, Lin L, Berends ET, Davies MR, Dougan G, Zhang F, Dahesh S, Shaw L, Gin J, Cunningham M, ... ... Nizet V, et al. The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design. Cell Host & Microbe. 15: 729-40. PMID 24922575 DOI: 10.1016/J.Chom.2014.05.009  0.81
2014 Ali SR, Fong JJ, Carlin AF, Busch TD, Linden R, Angata T, Areschoug T, Parast M, Varki N, Murray J, Nizet V, Varki A. Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus. The Journal of Experimental Medicine. 211: 1231-42. PMID 24799499 DOI: 10.1084/Jem.20131853  0.79
2014 Liu Y, Haste NM, Thienphrapa W, Li J, Nizet V, Hensler M, Li R. Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (III). Marine Drugs. 12: 2458-70. PMID 24796304 DOI: 10.3390/md12052458  0.816
2014 Chang YC, Olson J, Louie A, Crocker PR, Varki A, Nizet V. Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus. Journal of Molecular Medicine (Berlin, Germany). 92: 951-9. PMID 24788876 DOI: 10.1007/S00109-014-1157-Y  0.691
2014 Hensler ME, Jang KH, Thienphrapa W, Vuong L, Tran DN, Soubih E, Lin L, Haste NM, Cunningham ML, Kwan BP, Shaw KJ, Fenical W, Nizet V. Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus. The Journal of Antibiotics. 67: 549-53. PMID 24736856 DOI: 10.1038/Ja.2014.36  0.814
2014 Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, Dixon JE. Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 111: 5520-5. PMID 24706917 DOI: 10.1073/Pnas.1402218111  0.557
2014 Walker MJ, Barnett TC, McArthur JD, Cole JN, Gillen CM, Henningham A, Sriprakash KS, Sanderson-Smith ML, Nizet V. Disease manifestations and pathogenic mechanisms of group a Streptococcus. Clinical Microbiology Reviews. 27: 264-301. PMID 24696436 DOI: 10.1128/Cmr.00101-13  0.634
2014 Sakoulas G, Guram K, Reyes K, Nizet V, Zervos M. Human cathelicidin LL-37 resistance and increased daptomycin MIC in methicillin-resistant Staphylococcus aureus strain USA600 (ST45) are associated with increased mortality in a hospital setting. Journal of Clinical Microbiology. 52: 2172-4. PMID 24648548 DOI: 10.1128/Jcm.00189-14  0.381
2014 Opaluch AM, Schneider M, Chiang CY, Nguyen QT, Maestre AM, Mulder LC, Secundino I, De Jesus PD, König R, Simon V, Nizet V, MacLeod G, Varmuza S, Fernandez-Sesma A, Chanda SK. Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ. Plos One. 9: e89284. PMID 24586659 DOI: 10.1371/Journal.Pone.0089284  0.371
2014 Gonzalez DJ, Vuong L, Gonzalez IS, Keller N, McGrosso D, Hwang JH, Hung J, Zinkernagel A, Dixon JE, Dorrestein PC, Nizet V. Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking. Molecular & Cellular Proteomics : McP. 13: 1262-72. PMID 24567418 DOI: 10.1074/Mcp.M113.031336  0.809
2014 Askarian F, van Sorge NM, Sangvik M, Beasley FC, Henriksen JR, Sollid JU, van Strijp JA, Nizet V, Johannessen M. A Staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-κB signaling. Journal of Innate Immunity. 6: 485-98. PMID 24481289 DOI: 10.1159/000357618  0.825
2014 Randis TM, Gelber SE, Hooven TA, Abellar RG, Akabas LH, Lewis EL, Walker LB, Byland LM, Nizet V, Ratner AJ. Group B Streptococcus β-hemolysin/cytolysin breaches maternal-fetal barriers to cause preterm birth and intrauterine fetal demise in vivo. The Journal of Infectious Diseases. 210: 265-73. PMID 24474814 DOI: 10.1093/Infdis/Jiu067  0.314
2014 Yamanaka K, Reynolds KA, Kersten RD, Ryan KS, Gonzalez DJ, Nizet V, Dorrestein PC, Moore BS. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proceedings of the National Academy of Sciences of the United States of America. 111: 1957-62. PMID 24449899 DOI: 10.1073/Pnas.1319584111  0.583
2014 Chang YC, Olson J, Beasley FC, Tung C, Zhang J, Crocker PR, Varki A, Nizet V. Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo. Plos Pathogens. 10: e1003846. PMID 24391502 DOI: 10.1371/Journal.Ppat.1003846  0.818
2014 Sakoulas G, Rose W, Nonejuie P, Olson J, Pogliano J, Humphries R, Nizet V. Ceftaroline restores daptomycin activity against daptomycin-nonsusceptible vancomycin-resistant Enterococcus faecium. Antimicrobial Agents and Chemotherapy. 58: 1494-500. PMID 24366742 DOI: 10.1128/Aac.02274-13  0.388
2014 Franks SE, Ebrahimi C, Hollands A, Okumura CY, Aroian RV, Nizet V, McGillivray SM. Novel role for the yceGH tellurite resistance genes in the pathogenesis of Bacillus anthracis. Infection and Immunity. 82: 1132-40. PMID 24366250 DOI: 10.1128/Iai.01614-13  0.825
2014 Anderson EL, Cole JN, Olson J, Ryba B, Ghosh P, Nizet V. The fibrinogen-binding M1 protein reduces pharyngeal cell adherence and colonization phenotypes of M1T1 group A Streptococcus. The Journal of Biological Chemistry. 289: 3539-46. PMID 24356958 DOI: 10.1074/Jbc.M113.529537  0.811
2014 Padler-Karavani V, Hurtado-Ziola N, Chang YC, Sonnenburg JL, Ronaghy A, Yu H, Verhagen A, Nizet V, Chen X, Varki N, Varki A, Angata T. Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primates. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1280-93. PMID 24308974 DOI: 10.1096/Fj.13-241497  0.653
2014 Sakoulas G, Okumura CY, Thienphrapa W, Olson J, Nonejuie P, Dam Q, Dhand A, Pogliano J, Yeaman MR, Hensler ME, Bayer AS, Nizet V. Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus. Journal of Molecular Medicine (Berlin, Germany). 92: 139-49. PMID 24297496 DOI: 10.1007/S00109-013-1100-7  0.836
2014 Lin AE, Autran CA, Espanola SD, Bode L, Nizet V. Human milk oligosaccharides protect bladder epithelial cells against uropathogenic Escherichia coli invasion and cytotoxicity. The Journal of Infectious Diseases. 209: 389-98. PMID 23990566 DOI: 10.1093/Infdis/Jit464  0.669
2014 Ly D, Taylor JM, Tsatsaronis JA, Monteleone MM, Skora AS, Donald CA, Maddocks T, Nizet V, West NP, Ranson M, Walker MJ, McArthur JD, Sanderson-Smith ML. Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing. Journal of Innate Immunity. 6: 240-50. PMID 23969887 DOI: 10.1159/000353754  0.471
2014 Yamaguchi M, Terao Y, Mori-Yamaguchi Y, Domon H, Sakaue Y, Yagi T, Nishino K, Yamaguchi A, Nizet V, Kawabata S. Correction: Streptococcus pneumoniae Invades Erythrocytes and Utilizes Them to Evade Human Innate Immunity Plos One. 9. DOI: 10.1371/Annotation/De14E562-D899-48Da-B677-Ca61Cca2Cf5B  0.586
2013 Crotty Alexander LE, Marsh BJ, Timmer AM, Lin AE, Zainabadi K, Czopik A, Guarente L, Nizet V. Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection. Plos One. 8: e84481. PMID 24386389 DOI: 10.1371/Journal.Pone.0084481  0.833
2013 Barnett TC, Liebl D, Seymour LM, Gillen CM, Lim JY, Larock CN, Davies MR, Schulz BL, Nizet V, Teasdale RD, Walker MJ. The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication. Cell Host & Microbe. 14: 675-82. PMID 24331465 DOI: 10.1016/J.Chom.2013.11.003  0.745
2013 Grewal PK, Aziz PV, Uchiyama S, Rubio GR, Lardone RD, Le D, Varki NM, Nizet V, Marth JD. Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor. Proceedings of the National Academy of Sciences of the United States of America. 110: 20218-23. PMID 24284176 DOI: 10.1073/Pnas.1313905110  0.667
2013 Yamaguchi M, Terao Y, Mori-Yamaguchi Y, Domon H, Sakaue Y, Yagi T, Nishino K, Yamaguchi A, Nizet V, Kawabata S. Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity. Plos One. 8: e77282. PMID 24194877 DOI: 10.1371/Journal.Pone.0077282  0.684
2013 Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS. Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: E4407-16. PMID 24191063 DOI: 10.1073/Pnas.1315492110  0.577
2013 Guichard A, Cruz-Moreno B, Cruz-Moreno BC, Aguilar B, van Sorge NM, Kuang J, Kurkciyan AA, Wang Z, Hang S, Pineton de Chambrun GP, McCole DF, Watnick P, Nizet V, Bier E. Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions. Cell Host & Microbe. 14: 294-305. PMID 24034615 DOI: 10.1016/J.Chom.2013.08.001  0.758
2013 Nizet V, Yaksh T. Neuroscience: Bacteria get on your nerves. Nature. 501: 43-4. PMID 23965630 DOI: 10.1038/Nature12550  0.381
2013 Leire E, Olson J, Isaacs H, Nizet V, Hollands A. Role of hypoxia inducible factor-1 in keratinocyte inflammatory response and neutrophil recruitment. Journal of Inflammation (London, England). 10: 28. PMID 23937964 DOI: 10.1186/1476-9255-10-28  0.797
2013 Okumura CY, Anderson EL, Döhrmann S, Tran DN, Olson J, von Pawel-Rammingen U, Nizet V. IgG protease Mac/IdeS is not essential for phagocyte resistance or mouse virulence of M1T1 group A Streptococcus. Mbio. 4. PMID 23900173 DOI: 10.1128/Mbio.00499-13  0.824
2013 Berti AD, Sakoulas G, Nizet V, Tewhey R, Rose WE. β-Lactam antibiotics targeting PBP1 selectively enhance daptomycin activity against methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 57: 5005-12. PMID 23896478 DOI: 10.1128/Aac.00594-13  0.366
2013 Sjögren J, Struwe WB, Cosgrave EF, Rudd PM, Stervander M, Allhorn M, Hollands A, Nizet V, Collin M. EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein. The Biochemical Journal. 455: 107-18. PMID 23865566 DOI: 10.1042/Bj20130126  0.806
2013 Sanderson-Smith ML, Zhang Y, Ly D, Donahue D, Hollands A, Nizet V, Ranson M, Ploplis VA, Walker MJ, Castellino FJ. A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection. Plos Pathogens. 9: e1003469. PMID 23853591 DOI: 10.1371/Journal.Ppat.1003469  0.771
2013 Corriden R, Self T, Akong-Moore K, Nizet V, Kellam B, Briddon SJ, Hill SJ. Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes. Embo Reports. 14: 726-32. PMID 23817552 DOI: 10.1038/Embor.2013.89  0.796
2013 Sakoulas G, Nonejuie P, Nizet V, Pogliano J, Crum-Cianflone N, Haddad F. Treatment of high-level gentamicin-resistant Enterococcus faecalis endocarditis with daptomycin plus ceftaroline. Antimicrobial Agents and Chemotherapy. 57: 4042-5. PMID 23689728 DOI: 10.1128/Aac.02481-12  0.388
2013 Bhandari T, Olson J, Johnson RS, Nizet V. HIF-1α influences myeloid cell antigen presentation and response to subcutaneous OVA vaccination. Journal of Molecular Medicine (Berlin, Germany). 91: 1199-205. PMID 23686259 DOI: 10.1007/S00109-013-1052-Y  0.806
2013 Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, ... ... Nizet V, et al. Succinate is an inflammatory signal that induces IL-1β through HIF-1α. Nature. 496: 238-42. PMID 23535595 DOI: 10.1038/Nature11986  0.326
2013 Tsatsaronis JA, Hollands A, Cole JN, Maamary PG, Gillen CM, Ben Zakour NL, Kotb M, Nizet V, Beatson SA, Walker MJ, Sanderson-Smith ML. Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2633-43. PMID 23531597 DOI: 10.1096/Fj.12-226662  0.821
2013 Venturini C, Ong CL, Gillen CM, Ben-Zakour NL, Maamary PG, Nizet V, Beatson SA, Walker MJ. Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370. Infection and Immunity. 81: 2062-9. PMID 23529618 DOI: 10.1128/Iai.00192-13  0.395
2013 Angata T, Ishii T, Motegi T, Oka R, Taylor RE, Soto PC, Chang YC, Secundino I, Gao CX, Ohtsubo K, Kitazume S, Nizet V, Varki A, Gemma A, Kida K, et al. Loss of Siglec-14 reduces the risk of chronic obstructive pulmonary disease exacerbation. Cellular and Molecular Life Sciences : Cmls. 70: 3199-210. PMID 23519826 DOI: 10.1007/S00018-013-1311-7  0.627
2013 Jantsch J, Gerlach RG, Ensser A, Dahesh S, Popp I, Heeg C, Bleiziffer O, Merz T, Schulz T, Horch RE, Bogdan C, Nizet V, van der Linden M. Severe soft tissue infection caused by a non-beta-hemolytic Streptococcus pyogenes strain harboring a premature stop mutation in the sagC gene. Journal of Clinical Microbiology. 51: 1962-5. PMID 23515542 DOI: 10.1128/Jcm.00175-13  0.315
2013 Uchiyama S, Andreoni F, Zürcher C, Schilcher K, Ender M, Madon J, Matt U, Ghosh P, Nizet V, Schuepbach RA, Zinkernagel AS. Coiled-coil irregularities of the M1 protein structure promote M1-fibrinogen interaction and influence group A Streptococcus host cell interactions and virulence. Journal of Molecular Medicine (Berlin, Germany). 91: 861-9. PMID 23443671 DOI: 10.1007/S00109-013-1012-6  0.748
2013 van Sorge NM, Beasley FC, Gusarov I, Gonzalez DJ, von Köckritz-Blickwede M, Anik S, Borkowski AW, Dorrestein PC, Nudler E, Nizet V. Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development. The Journal of Biological Chemistry. 288: 6417-26. PMID 23322784 DOI: 10.1074/Jbc.M112.448738  0.829
2013 Crotty Alexander LE, Akong-Moore K, Feldstein S, Johansson P, Nguyen A, McEachern EK, Nicatia S, Cowburn AS, Olson J, Cho JY, Isaacs H, Johnson RS, Broide DH, Nizet V. Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function. Journal of Molecular Medicine (Berlin, Germany). 91: 637-44. PMID 23250618 DOI: 10.1007/S00109-012-0986-9  0.772
2013 Zhu W, Zhang Y, Sinko W, Hensler ME, Olson J, Molohon KJ, Lindert S, Cao R, Li K, Wang K, Wang Y, Liu YL, Sankovsky A, de Oliveira CA, Mitchell DA, ... Nizet V, et al. Antibacterial drug leads targeting isoprenoid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 123-8. PMID 23248302 DOI: 10.1073/Pnas.1219899110  0.717
2013 Crotty Alexander LE, Nicatia S, McEachern E, Johnson R, Broide DH, Nizet V. Hypoxia Inducible Factor (HIF) Alpha Subunits Modulate Eosinophil Migration, Oxidative Burst, and Degranulation Journal of Allergy and Clinical Immunology. 131: AB239. DOI: 10.1016/J.Jaci.2012.12.1517  0.761
2012 Kuang E, Okumura CY, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA. Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection. Plos Genetics. 8: e1003007. PMID 23093945 DOI: 10.1371/Journal.Pgen.1003007  0.761
2012 Dahesh S, Nizet V, Cole JN. Study of streptococcal hemoprotein receptor (Shr) in iron acquisition and virulence of M1T1 group A streptococcus. Virulence. 3: 566-75. PMID 23076332 DOI: 10.4161/Viru.21933  0.646
2012 Haste NM, Thienphrapa W, Tran DN, Loesgen S, Sun P, Nam SJ, Jensen PR, Fenical W, Sakoulas G, Nizet V, Hensler ME. Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. The Journal of Antibiotics. 65: 593-8. PMID 23047246 DOI: 10.1038/Ja.2012.77  0.824
2012 Hollands A, Gonzalez D, Leire E, Donald C, Gallo RL, Sanderson-Smith M, Dorrestein PC, Nizet V. A bacterial pathogen co-opts host plasmin to resist killing by cathelicidin antimicrobial peptides. The Journal of Biological Chemistry. 287: 40891-7. PMID 23038245 DOI: 10.1074/Jbc.M112.404582  0.828
2012 Rose WE, Eickhoff JC, Shukla SK, Pantrangi M, Rooijakkers S, Cosgrove SE, Nizet V, Sakoulas G. Elevated serum interleukin-10 at time of hospital admission is predictive of mortality in patients with Staphylococcus aureus bacteremia. The Journal of Infectious Diseases. 206: 1604-11. PMID 22966128 DOI: 10.1093/Infdis/Jis552  0.587
2012 Cole JN, Aziz RK, Kuipers K, Timmer AM, Nizet V, van Sorge NM. A conserved UDP-glucose dehydrogenase encoded outside the hasABC operon contributes to capsule biogenesis in group A Streptococcus. Journal of Bacteriology. 194: 6154-61. PMID 22961854 DOI: 10.1128/Jb.01317-12  0.808
2012 Humphries RM, Kelesidis T, Tewhey R, Rose WE, Schork N, Nizet V, Sakoulas G. Genotypic and phenotypic evaluation of the evolution of high-level daptomycin nonsusceptibility in vancomycin-resistant Enterococcus faecium. Antimicrobial Agents and Chemotherapy. 56: 6051-3. PMID 22948885 DOI: 10.1128/Aac.01318-12  0.309
2012 Akong-Moore K, Chow OA, von Köckritz-Blickwede M, Nizet V. Influences of chloride and hypochlorite on neutrophil extracellular trap formation. Plos One. 7: e42984. PMID 22912772 DOI: 10.1371/Journal.Pone.0042984  0.801
2012 Maamary PG, Ben Zakour NL, Cole JN, Hollands A, Aziz RK, Barnett TC, Cork AJ, Henningham A, Sanderson-Smith M, McArthur JD, Venturini C, Gillen CM, Kirk JK, Johnson DR, Taylor WL, ... ... Nizet V, et al. Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4675-84. PMID 22878963 DOI: 10.1096/Fj.12-212142  0.811
2012 Bebien M, Hensler ME, Davanture S, Hsu LC, Karin M, Park JM, Alexopoulou L, Liu GY, Nizet V, Lawrence T. The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity. Plos Pathogens. 8: e1002812. PMID 22829768 DOI: 10.1371/Journal.Ppat.1002812  0.768
2012 Branitzki-Heinemann K, Okumura CY, Völlger L, Kawakami Y, Kawakami T, Naim HY, Nizet V, Von Köckritz-Blickwede M. A novel role for the transcription factor HIF-1α in the formation of mast cell extracellular traps. The Biochemical Journal. 446: 159-63. PMID 22738198 DOI: 10.1042/Bj20120658  0.812
2012 Uchiyama S, Andreoni F, Schuepbach RA, Nizet V, Zinkernagel AS. Dnase Sda1 allows invasive M1T1 group a streptococcus to prevent TLR9-dependent recognition Plos Pathogens. 8. PMID 22719247 DOI: 10.1371/Journal.Ppat.1002736  0.771
2012 Liu Y, Haste NM, Thienphrapa W, Nizet V, Hensler M, Li R. Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (I). Marine Drugs. 10: 953-62. PMID 22690153 DOI: 10.3390/Md10040953  0.817
2012 Wang X, Mitra N, Secundino I, Banda K, Cruz P, Padler-Karavani V, Verhagen A, Reid C, Lari M, Rizzi E, Balsamo C, Corti G, De Bellis G, Longo L, ... ... Nizet V, et al. Specific inactivation of two immunomodulatory SIGLEC genes during human evolution. Proceedings of the National Academy of Sciences of the United States of America. 109: 9935-40. PMID 22665810 DOI: 10.1073/Pnas.1119459109  0.557
2012 Zhang Y, Fu-Yang Lin, Li K, Zhu W, Liu YL, Cao R, Pang R, Lee E, Axelson J, Hensler M, Wang K, Molohon KJ, Wang Y, Mitchell DA, Nizet V, et al. HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis. Acs Medicinal Chemistry Letters. 3: 402-406. PMID 22662288 DOI: 10.1021/Ml300038T  0.685
2012 Gonzalez DJ, Xu Y, Yang YL, Esquenazi E, Liu WT, Edlund A, Duong T, Du L, Molnár I, Gerwick WH, Jensen PR, Fischbach M, Liaw CC, Straight P, Nizet V, et al. Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. Journal of Proteomics. 75: 5069-76. PMID 22641157 DOI: 10.1016/J.Jprot.2012.05.036  0.556
2012 Fair RJ, Hensler ME, Thienphrapa W, Dam QN, Nizet V, Tor Y. Selectively guanidinylated aminoglycosides as antibiotics. Chemmedchem. 7: 1237-44. PMID 22639134 DOI: 10.1002/Cmdc.201200150  0.733
2012 van der Westhuyzen R, Hammons JC, Meier JL, Dahesh S, Moolman WJ, Pelly SC, Nizet V, Burkart MD, Strauss E. The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chemistry & Biology. 19: 559-71. PMID 22633408 DOI: 10.1016/J.Chembiol.2012.03.013  0.31
2012 Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, Yamaguchi M, Nizet V, Dahl R, Thomas DD, Tait SW, et al. Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy. Genes & Development. 26: 1041-54. PMID 22588718 DOI: 10.1101/Gad.184325.111  0.596
2012 Henningham A, Chiarot E, Gillen CM, Cole JN, Rohde M, Fulde M, Ramachandran V, Cork AJ, Hartas J, Magor G, Djordjevic SP, Cordwell SJ, Kobe B, Sriprakash KS, Nizet V, et al. Conserved anchorless surface proteins as group A streptococcal vaccine candidates. Journal of Molecular Medicine (Berlin, Germany). 90: 1197-207. PMID 22527883 DOI: 10.1007/S00109-012-0897-9  0.59
2012 Hertzén E, Johansson L, Kansal R, Hecht A, Dahesh S, Janos M, Nizet V, Kotb M, Norrby-Teglund A. Intracellular Streptococcus pyogenes in human macrophages display an altered gene expression profile. Plos One. 7: e35218. PMID 22511985 DOI: 10.1371/Journal.Pone.0035218  0.396
2012 Chiang CY, Engel A, Opaluch AM, Ramos I, Maestre AM, Secundino I, De Jesus PD, Nguyen QT, Welch G, Bonamy GM, Miraglia LJ, Orth AP, Nizet V, Fernandez-Sesma A, Zhou Y, et al. Cofactors required for TLR7- and TLR9-dependent innate immune responses. Cell Host & Microbe. 11: 306-18. PMID 22423970 DOI: 10.1016/J.Chom.2012.02.002  0.368
2012 Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. The Journal of Biological Chemistry. 287: 13889-98. PMID 22371493 DOI: 10.1074/Jbc.M112.349860  0.814
2012 Okumura CY, Hollands A, Tran DN, Olson J, Dahesh S, von Köckritz-Blickwede M, Thienphrapa W, Corle C, Jeung SN, Kotsakis A, Shalwitz RA, Johnson RS, Nizet V. A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection. Journal of Molecular Medicine (Berlin, Germany). 90: 1079-89. PMID 22371073 DOI: 10.1007/S00109-012-0882-3  0.831
2012 Jongerius I, von Köckritz-Blickwede M, Horsburgh MJ, Ruyken M, Nizet V, Rooijakkers SH. Staphylococcus aureus virulence is enhanced by secreted factors that block innate immune defenses. Journal of Innate Immunity. 4: 301-11. PMID 22327617 DOI: 10.1159/000334604  0.696
2012 Lin FY, Zhang Y, Hensler M, Liu YL, Chow OA, Zhu W, Wang K, Pang R, Thienphrapa W, Nizet V, Oldfield E. Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics. Chemmedchem. 7: 561-4. PMID 22290830 DOI: 10.1002/Cmdc.201100589  0.805
2012 Sakoulas G, Nam SJ, Loesgen S, Fenical W, Jensen PR, Nizet V, Hensler M. Novel bacterial metabolite merochlorin A demonstrates in vitro activity against multi-drug resistant methicillin-resistant Staphylococcus aureus. Plos One. 7: e29439. PMID 22279537 DOI: 10.1371/Journal.Pone.0029439  0.731
2012 McGillivray SM, Tran DN, Ramadoss NS, Alumasa JN, Okumura CY, Sakoulas G, Vaughn MM, Zhang DX, Keiler KC, Nizet V. Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell envelope-active antibiotics. Antimicrobial Agents and Chemotherapy. 56: 1854-61. PMID 22252821 DOI: 10.1128/Aac.05131-11  0.829
2012 Chang YC, Uchiyama S, Varki A, Nizet V. Leukocyte inflammatory responses provoked by pneumococcal sialidase. Mbio. 3. PMID 22215570 DOI: 10.1128/Mbio.00220-11  0.788
2012 Sakoulas G, Bayer AS, Pogliano J, Tsuji BT, Yang SJ, Mishra NN, Nizet V, Yeaman MR, Moise PA. Ampicillin enhances daptomycin- and cationic host defense peptide-mediated killing of ampicillin- and vancomycin-resistant Enterococcus faecium. Antimicrobial Agents and Chemotherapy. 56: 838-44. PMID 22123698 DOI: 10.1128/Aac.05551-11  0.386
2012 Guichard A, Nizet V, Bier E. New insights into the biological effects of anthrax toxins: linking cellular to organismal responses. Microbes and Infection / Institut Pasteur. 14: 97-118. PMID 21930233 DOI: 10.1016/J.Micinf.2011.08.016  0.402
2012 Zinkernagel AS, Hruz P, Uchiyama S, von Köckritz-Blickwede M, Schuepbach RA, Hayashi T, Carson DA, Nizet V. Importance of Toll-like receptor 9 in host defense against M1T1 group A Streptococcus infections. Journal of Innate Immunity. 4: 213-8. PMID 21860217 DOI: 10.1159/000329550  0.761
2012 Carland TM, Locke JB, Nizet V, Gerwick L. Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio). Developmental and Comparative Immunology. 36: 31-8. PMID 21683091 DOI: 10.1016/J.Dci.2011.05.013  0.7
2012 Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Nizet V, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127  0.682
2011 Kho MF, Bellier A, Balasubramani V, Hu Y, Hsu W, Nielsen-LeRoux C, McGillivray SM, Nizet V, Aroian RV. The pore-forming protein Cry5B elicits the pathogenicity of Bacillus sp. against Caenorhabditis elegans. Plos One. 6: e29122. PMID 22216181 DOI: 10.1371/Journal.Pone.0029122  0.777
2011 Cole JN, Barnett TC, Nizet V, Walker MJ. Molecular insight into invasive group A streptococcal disease. Nature Reviews. Microbiology. 9: 724-36. PMID 21921933 DOI: 10.1038/Nrmicro2648  0.615
2011 Kinjo Y, Illarionov P, Vela JL, Pei B, Girardi E, Li X, Li Y, Imamura M, Kaneko Y, Okawara A, Miyazaki Y, Gómez-Velasco A, Rogers P, Dahesh S, Uchiyama S, ... ... Nizet V, et al. Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nature Immunology. 12: 966-74. PMID 21892173 DOI: 10.1038/Ni.2096  0.657
2011 Nordström T, Movert E, Olin AI, Ali SR, Nizet V, Varki A, Areschoug T. Human Siglec-5 inhibitory receptor and immunoglobulin A (IgA) have separate binding sites in streptococcal β protein Journal of Biological Chemistry. 286: 33981-33991. PMID 21795693 DOI: 10.1074/Jbc.M111.251728  0.636
2011 Sun P, Maloney KN, Nam SJ, Haste NM, Raju R, Aalbersberg W, Jensen PR, Nizet V, Hensler ME, Fenical W. Fijimycins A-C, three antibacterial etamycin-class depsipeptides from a marine-derived Streptomyces sp. Bioorganic & Medicinal Chemistry. 19: 6557-62. PMID 21745747 DOI: 10.1016/J.Bmc.2011.06.053  0.79
2011 Haste NM, Farnaes L, Perera VR, Fenical W, Nizet V, Hensler ME. Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus Marine Drugs. 9: 680-689. PMID 21731557 DOI: 10.3390/Md9040680  0.814
2011 Chang YC, Wang Z, Flax LA, Xu D, Esko JD, Nizet V, Baron MJ. Glycosaminoglycan binding facilitates entry of a bacterial pathogen into central nervous systems. Plos Pathogens. 7: e1002082. PMID 21731486 DOI: 10.1371/Journal.Ppat.1002082  0.57
2011 Gonzalez DJ, Haste NM, Hollands A, Fleming TC, Hamby M, Pogliano K, Nizet V, Dorrestein PC. Microbial competition between Bacillus subtilis and Staphylococcus aureus monitored by imaging mass spectrometry. Microbiology (Reading, England). 157: 2485-92. PMID 21719540 DOI: 10.1099/Mic.0.048736-0  0.8
2011 Dhand A, Bayer AS, Pogliano J, Yang SJ, Bolaris M, Nizet V, Wang G, Sakoulas G. Use of antistaphylococcal beta-lactams to increase daptomycin activity in eradicating persistent bacteremia due to methicillin-resistant Staphylococcus aureus: role of enhanced daptomycin binding. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 53: 158-63. PMID 21690622 DOI: 10.1093/Cid/Cir340  0.357
2011 Ali SR, Timmer AM, Bilgrami S, Park EJ, Eckmann L, Nizet V, Karin M. Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage. Immunity. 35: 34-44. PMID 21683629 DOI: 10.1016/J.Immuni.2011.04.015  0.818
2011 Sjögren J, Okumura CY, Collin M, Nizet V, Hollands A. Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence Bmc Microbiology. 11. PMID 21619648 DOI: 10.1186/1471-2180-11-120  0.825
2011 Amelung S, Nerlich A, Rohde M, Spellerberg B, Cole JN, Nizet V, Chhatwal GS, Talay SR. The FbaB-type fibronectin-binding protein of Streptococcus pyogenes promotes specific invasion into endothelial cells. Cellular Microbiology. 13: 1200-11. PMID 21615663 DOI: 10.1111/J.1462-5822.2011.01610.X  0.607
2011 Haste NM, Hughes CC, Tran DN, Fenical W, Jensen PR, Nizet V, Hensler ME. Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 55: 3305-12. PMID 21502631 DOI: 10.1128/Aac.01211-10  0.81
2011 Kisseleva T, von Köckritz-Blickwede M, Reichart D, McGillvray SM, Wingender G, Kronenberg M, Glass CK, Nizet V, Brenner DA. Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. Journal of Molecular Medicine (Berlin, Germany). 89: 997-1013. PMID 21499735 DOI: 10.1007/S00109-011-0756-0  0.332
2011 Nicolaou KC, Simmons NL, Chen JS, Haste NM, Nizet V. Total synthesis and biological evaluation of marinopyrrole A and analogues. Tetrahedron Letters. 52: 2041-2043. PMID 21499535 DOI: 10.1016/J.Tetlet.2010.09.059  0.705
2011 Macheboeuf P, Buffalo C, Fu CY, Zinkernagel AS, Cole JN, Johnson JE, Nizet V, Ghosh P. Streptococcal M1 protein constructs a pathological host fibrinogen network. Nature. 472: 64-8. PMID 21475196 DOI: 10.1038/Nature09967  0.698
2011 Yang H, Sikavi C, Tran K, McGillivray SM, Nizet V, Yung M, Chang A, Miller JH. Papillation in Bacillus anthracis colonies: a tool for finding new mutators. Molecular Microbiology. 79: 1276-93. PMID 21205011 DOI: 10.1111/J.1365-2958.2011.07519.X  0.725
2011 Reiss A, Braun JS, Jäger K, Freyer D, Laube G, Bührer C, Felderhoff-Müser U, Stadelmann C, Nizet V, Weber JR. Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. The Journal of Infectious Diseases. 203: 393-400. PMID 21186256 DOI: 10.1093/Infdis/Jiq047  0.314
2011 Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ. Nature Immunology. 12: 144-50. PMID 21170027 DOI: 10.1038/Ni.1976  0.768
2010 Chow OA, von Köckritz-Blickwede M, Bright AT, Hensler ME, Zinkernagel AS, Cogen AL, Gallo RL, Monestier M, Wang Y, Glass CK, Nizet V. Statins enhance formation of phagocyte extracellular traps. Cell Host & Microbe. 8: 445-54. PMID 21075355 DOI: 10.1016/J.Chom.2010.10.005  0.82
2010 Guichard A, McGillivray SM, Cruz-Moreno B, van Sorge NM, Nizet V, Bier E. Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst. Nature. 467: 854-8. PMID 20944747 DOI: 10.1038/Nature09446  0.809
2010 Berends ET, Horswill AR, Haste NM, Monestier M, Nizet V, von Köckritz-Blickwede M. Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps. Journal of Innate Immunity. 2: 576-86. PMID 20829609 DOI: 10.1159/000319909  0.846
2010 Cole JN, Pence MA, von Köckritz-Blickwede M, Hollands A, Gallo RL, Walker MJ, Nizet V. M protein and hyaluronic acid capsule are essential for in vivo selection of covRS mutations characteristic of invasive serotype M1T1 group A Streptococcus. Mbio. 1. PMID 20827373 DOI: 10.1128/Mbio.00191-10  0.816
2010 Pence MA, Rooijakkers SH, Cogen AL, Cole JN, Hollands A, Gallo RL, Nizet V. Streptococcal inhibitor of complement promotes innate immune resistance phenotypes of invasive M1T1 group A Streptococcus. Journal of Innate Immunity. 2: 587-95. PMID 20814187 DOI: 10.1159/000317672  0.822
2010 Maamary PG, Sanderson-Smith ML, Aziz RK, Hollands A, Cole JN, McKay FC, McArthur JD, Kirk JK, Cork AJ, Keefe RJ, Kansal RG, Sun H, Taylor WL, Chhatwal GS, Ginsburg D, ... Nizet V, et al. Parameters governing invasive disease propensity of non-M1 serotype group A streptococci. Journal of Innate Immunity. 2: 596-606. PMID 20814186 DOI: 10.1159/000317640  0.805
2010 Liu WT, Yang YL, Xu Y, Lamsa A, Haste NM, Yang JY, Ng J, Gonzalez D, Ellermeier CD, Straight PD, Pevzner PA, Pogliano J, Nizet V, Pogliano K, Dorrestein PC. Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 107: 16286-90. PMID 20805502 DOI: 10.1073/Pnas.1008368107  0.787
2010 Derbal S, Hensler M, Fang W, Nizet V, Ghedira K, Nefzi A. On resin amino acid side chain attachment strategy for the head to tail synthesis of new glutamine containing gramicidin-S analogs and their antimicrobial activity Bioorganic and Medicinal Chemistry Letters. 20: 5701-5704. PMID 20800485 DOI: 10.1016/J.Bmcl.2010.08.015  0.724
2010 Taylor RE, Gregg CJ, Padler-Karavani V, Ghaderi D, Yu H, Huang S, Sorensen RU, Chen X, Inostroza J, Nizet V, Varki A. Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid. The Journal of Experimental Medicine. 207: 1637-46. PMID 20624889 DOI: 10.1084/Jem.20100575  0.478
2010 Rooijakkers SH, Rasmussen SL, McGillivray SM, Bartnikas TB, Mason AB, Friedlander AM, Nizet V. Human transferrin confers serum resistance against Bacillus anthracis. The Journal of Biological Chemistry. 285: 27609-13. PMID 20615872 DOI: 10.1074/Jbc.M110.154930  0.805
2010 Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. The Journal of Biological Chemistry. 285: 28220-8. PMID 20581111 DOI: 10.1074/Jbc.M110.118554  0.799
2010 Kaur SJ, Nerlich A, Bergmann S, Rohde M, Fulde M, Zähner D, Hanski E, Zinkernagel A, Nizet V, Chhatwal GS, Talay SR. The CXC chemokine-degrading protease SpyCep of Streptococcus pyogenes promotes its uptake into endothelial cells. The Journal of Biological Chemistry. 285: 27798-805. PMID 20562101 DOI: 10.1074/Jbc.M109.098053  0.603
2010 Hollands A, Pence MA, Timmer AM, Osvath SR, Turnbull L, Whitchurch CB, Walker MJ, Nizet V. Genetic switch to hypervirulence reduces colonization phenotypes of the globally disseminated group A streptococcus M1T1 clone. The Journal of Infectious Diseases. 202: 11-9. PMID 20507231 DOI: 10.1086/653124  0.782
2010 Locke JB, Vicknair MR, Ostland VE, Nizet V, Buchanan JT. Evaluation of Streptococcus iniae killed bacterin and live attenuated vaccines in hybrid striped bass through injection and bath immersion. Diseases of Aquatic Organisms. 89: 117-23. PMID 20402229 DOI: 10.3354/Dao02192  0.752
2010 Aziz RK, Nizet V. Pathogen microevolution in high resolution Science Translational Medicine. 2. PMID 20371473 DOI: 10.1126/Scitranslmed.3000713  0.369
2010 Haste NM, Perera VR, Maloney KN, Tran DN, Jensen P, Fenical W, Nizet V, Hensler ME. Activity of the streptogramin antibiotic etamycin against methicillin-resistant Staphylococcus aureus. The Journal of Antibiotics. 63: 219-24. PMID 20339399 DOI: 10.1038/Ja.2010.22  0.819
2010 Weiman S, Uchiyama S, Lin FY, Chaffin D, Varki A, Nizet V, Lewis AL. O-Acetylation of sialic acid on Group B Streptococcus inhibits neutrophil suppression and virulence. The Biochemical Journal. 428: 163-8. PMID 20334627 DOI: 10.1042/Bj20100232  0.788
2010 Kurupati P, Turner CE, Tziona I, Lawrenson RA, Alam FM, Nohadani M, Stamp GW, Zinkernagel AS, Nizet V, Edwards RJ, Sriskandan S. Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract. Molecular Microbiology. 76: 1387-97. PMID 20158613 DOI: 10.1111/J.1365-2958.2010.07065.X  0.627
2010 Cogen AL, Yamasaki K, Muto J, Sanchez KM, Crotty Alexander L, Tanios J, Lai Y, Kim JE, Nizet V, Gallo RL. Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. Plos One. 5: e8557. PMID 20052280 DOI: 10.1371/Journal.Pone.0008557  0.448
2010 Crotty Alexander LE, Maisey HC, Timmer AM, Rooijakkers SH, Gallo RL, von Köckritz-Blickwede M, Nizet V. M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. Journal of Molecular Medicine (Berlin, Germany). 88: 371-81. PMID 19960175 DOI: 10.1007/S00109-009-0566-9  0.824
2010 Milani CJ, Aziz RK, Locke JB, Dahesh S, Nizet V, Buchanan JT. The novel polysaccharide deacetylase homologue Pdi contributes to virulence of the aquatic pathogen Streptococcus iniae. Microbiology (Reading, England). 156: 543-54. PMID 19762441 DOI: 10.1099/Mic.0.028365-0  0.826
2010 Cogen AL, Yamasaki K, Sanchez KM, Dorschner RA, Lai Y, MacLeod DT, Torpey JW, Otto M, Nizet V, Kim JE, Gallo RL. Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. The Journal of Investigative Dermatology. 130: 192-200. PMID 19710683 DOI: 10.1038/Jid.2009.243  0.376
2010 Berends ETM, Horswill AR, Haste NM, Monestier M, Nizet V, Köckritz-Blickwede Mv, Hertzén E, Johansson L, Wallin R, Schmidt H, Kroll M, Rehn AP, Kotb M, Mörgelin M, Norrby-Teglund A, et al. Contents Vol. 2, 2010 Journal of Innate Immunity. 2. DOI: 10.1159/000321132  0.742
2010 Berends ETM, Horswill AR, Haste NM, Monestier M, Nizet V, Köckritz-Blickwede Mv, Hertzén E, Johansson L, Wallin R, Schmidt H, Kroll M, Rehn AP, Kotb M, Mörgelin M, Norrby-Teglund A, et al. Subject Index Vol. 2, 2010 Journal of Innate Immunity. 2: 627-628. DOI: 10.1159/000321131  0.749
2010 Köckritz-Blickwede Mv, Chow O, Ghochani M, Nizet V. Visualization and functional evaluation of phagocyte extracellular traps Methods in Microbiology. 37: 139-160. DOI: 10.1016/S0580-9517(10)37007-3  0.826
2009 McGillivray SM, Ebrahimi CM, Fisher N, Sabet M, Zhang DX, Chen Y, Haste NM, Aroian RV, Gallo RL, Guiney DG, Friedlander AM, Koehler TM, Nizet V. ClpX contributes to innate defense peptide resistance and virulence phenotypes of Bacillus anthracis. Journal of Innate Immunity. 1: 494-506. PMID 20375606 DOI: 10.1159/000225955  0.824
2009 Lauth X, von Köckritz-Blickwede M, McNamara CW, Myskowski S, Zinkernagel AS, Beall B, Ghosh P, Gallo RL, Nizet V. M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. Journal of Innate Immunity. 1: 202-14. PMID 20375578 DOI: 10.1159/000203645  0.824
2009 von Köckritz-Blickwede M, Chow OA, Nizet V. Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps. Blood. 114: 5245-6. PMID 20007813 DOI: 10.1182/Blood-2009-08-240713  0.79
2009 Liu GY, Nizet V. Color me bad: microbial pigments as virulence factors Trends in Microbiology. 17: 406-413. PMID 19726196 DOI: 10.1016/J.Tim.2009.06.006  0.517
2009 Nizet V, Johnson RS. Interdependence of hypoxic and innate immune responses. Nature Reviews. Immunology. 9: 609-17. PMID 19704417 DOI: 10.1038/Nri2607  0.386
2009 Uchiyama S, Carlin AF, Khosravi A, Weiman S, Banerjee A, Quach D, Hightower G, Mitchell TJ, Doran KS, Nizet V. The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. The Journal of Experimental Medicine. 206: 1845-52. PMID 19687228 DOI: 10.1084/Jem.20090386  0.813
2009 Lewis AL, Desa N, Hansen EE, Knirel YA, Gordon JI, Gagneux P, Nizet V, Varki A. Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure. Proceedings of the National Academy of Sciences of the United States of America. 106: 13552-7. PMID 19666579 DOI: 10.1073/Pnas.0902431106  0.669
2009 Weiman S, Dahesh S, Carlin AF, Varki A, Nizet V, Lewis AL. Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: phenotypic and functional impact. Glycobiology. 19: 1204-13. PMID 19643844 DOI: 10.1093/Glycob/Cwp111  0.789
2009 Jann NJ, Schmaler M, Kristian SA, Radek KA, Gallo RL, Nizet V, Peschel A, Landmann R. Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin Journal of Leukocyte Biology. 86: 1159-1169. PMID 19638500 DOI: 10.1189/Jlb.0209053  0.787
2009 Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. Plos One. 4: e6387. PMID 19633710 DOI: 10.1371/Journal.Pone.0006387  0.551
2009 Carlin AF, Chang YC, Areschoug T, Lindahl G, Hurtado-Ziola N, King CC, Varki A, Nizet V. Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5. The Journal of Experimental Medicine. 206: 1691-9. PMID 19596804 DOI: 10.1084/Jem.20090691  0.79
2009 Hruz P, Zinkernagel AS, Jenikova G, Botwin GJ, Hugot JP, Karin M, Nizet V, Eckmann L. NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 12873-8. PMID 19541630 DOI: 10.1073/Pnas.0904958106  0.659
2009 Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. Journal of Medicinal Chemistry. 52: 3869-80. PMID 19456099 DOI: 10.1021/Jm9001764  0.76
2009 Von Köckritz-Blickwede M, Nizet V. Innate immunity turned inside-out: Antimicrobial defense by phagocyte extracellular traps Journal of Molecular Medicine. 87: 775-783. PMID 19444424 DOI: 10.1007/S00109-009-0481-0  0.398
2009 Cox KH, Ruiz-Bustos E, Courtney HS, Dale JB, Pence MA, Nizet V, Aziz RK, Gerling I, Price SM, Hasty DL. Inactivation of DltA modulates virulence factor expression in Streptococcus pyogenes. Plos One. 4: e5366. PMID 19401780 DOI: 10.1371/Journal.Pone.0005366  0.713
2009 Sorge NMV, Quach D, Gurney MA, Sullam PM, Nizet V, Doran KS. The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier Journal of Infectious Diseases. 199: 1479-1487. PMID 19392623 DOI: 10.1086/598217  0.578
2009 Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, Zinkernagel RM. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections. Proceedings of the National Academy of Sciences of the United States of America. 106: 7107-12. PMID 19351895 DOI: 10.1073/Pnas.0901162106  0.647
2009 Da Silva FP, Gallo RL, Nizet V. Differing effects of exogenous or endogenous cathelicidin on macrophage toll-like receptor signaling Immunology and Cell Biology. 87: 496-500. PMID 19350049 DOI: 10.1038/Icb.2009.19  0.353
2009 Mitchell DA, Lee SW, Pence MA, Markley AL, Limm JD, Nizet V, Dixon JE. Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. The Journal of Biological Chemistry. 284: 13004-12. PMID 19286651 DOI: 10.1074/Jbc.M900802200  0.752
2009 Pinheiro Da Silva F, Nizet V. Cell death during sepsis: Integration of disintegration in the inflammatory response to overwhelming infection Apoptosis. 14: 509-521. PMID 19199035 DOI: 10.1007/S10495-009-0320-3  0.354
2009 Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A. Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response. Blood. 113: 3333-6. PMID 19196661 DOI: 10.1182/Blood-2008-11-187302  0.824
2009 Sendi P, Johansson L, Dahesh S, Van-Sorge NM, Darenberg J, Norgren M, Sjölin J, Nizet V, Norrby-Teglund A. Bacterial phenotype variants in group B streptococcal toxic shock syndrome. Emerging Infectious Diseases. 15: 223-32. PMID 19193266 DOI: 10.3201/Eid1502.080990  0.354
2009 Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, Oldfield E. Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus. Journal of Medicinal Chemistry. 52: 976-88. PMID 19191557 DOI: 10.1021/Jm801023U  0.701
2009 Courtney HS, Ofek I, Penfound T, Nizet V, Pence MA, Kreikemeyer B, Podbielski A, Podbielbski A, Hasty DL, Dale JB. Relationship between expression of the family of M proteins and lipoteichoic acid to hydrophobicity and biofilm formation in Streptococcus pyogenes. Plos One. 4: e4166. PMID 19132104 DOI: 10.1371/Journal.Pone.0004166  0.698
2009 Timmer AM, Timmer JC, Pence MA, Hsu LC, Ghochani M, Frey TG, Karin M, Salvesen GS, Nizet V. Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis. The Journal of Biological Chemistry. 284: 862-71. PMID 19001420 DOI: 10.1074/Jbc.M804632200  0.81
2008 Gallo RL, Nizet V. Innate barriers against infection and associated disorders. Drug Discovery Today. Disease Mechanisms. 5: 145-152. PMID 19492071 DOI: 10.1016/J.Ddmec.2008.04.009  0.392
2008 Hollands A, Aziz RK, Kansal R, Kotb M, Nizet V, Walker MJ. A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence. Plos One. 3: e4102. PMID 19116661 DOI: 10.1371/Journal.Pone.0004102  0.749
2008 Maisey HC, Doran KS, Nizet V. Recent advances in understanding the molecular basis of group B Streptococcus virulence. Expert Reviews in Molecular Medicine. 10: e27. PMID 18803886 DOI: 10.1017/S1462399408000811  0.609
2008 Nizet V, Rothenberg ME. Mitochondrial missile defense Nature Medicine. 14: 910-912. PMID 18776879 DOI: 10.1038/Nm0908-910  0.303
2008 Zinkernagel AS, Timmer AM, Pence MA, Locke JB, Buchanan JT, Turner CE, Mishalian I, Sriskandan S, Hanski E, Nizet V. The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing. Cell Host & Microbe. 4: 170-8. PMID 18692776 DOI: 10.1016/J.Chom.2008.07.002  0.811
2008 Locke JB, Aziz RK, Vicknair MR, Nizet V, Buchanan JT. Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development. Plos One. 3: e2824. PMID 18665241 DOI: 10.1371/Journal.Pone.0002824  0.774
2008 Hensler ME, Miyamoto S, Nizet V. Group B streptococcal beta-hemolysin/cytolysin directly impairs cardiomyocyte viability and function. Plos One. 3: e2446. PMID 18560574 DOI: 10.1371/Journal.Pone.0002446  0.675
2008 Dahesh S, Hensler ME, Van Sorge NM, Gertz RE, Schrag S, Nizet V, Beall BW. Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. Antimicrobial Agents and Chemotherapy. 52: 2915-8. PMID 18541727 DOI: 10.1128/Aac.00461-08  0.787
2008 Timmer AM, Nizet V. IKKbeta/NF-kappaB and the miscreant macrophage. The Journal of Experimental Medicine. 205: 1255-9. PMID 18519650 DOI: 10.1084/Jem.20081056  0.767
2008 Kraus D, Herbert S, Kristian SA, Khosravi A, Nizet V, Götz F, Peschel A. The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses Bmc Microbiology. 8. PMID 18518949 DOI: 10.1186/1471-2180-8-85  0.76
2008 Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, Humke EW, Eckmann L, Powell JJ, Nizet V, Dixit VM, Karin M. A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proceedings of the National Academy of Sciences of the United States of America. 105: 7803-8. PMID 18511561 DOI: 10.1073/Pnas.0802726105  0.782
2008 Grewal PK, Uchiyama S, Ditto D, Varki N, Le DT, Nizet V, Marth JD. The Ashwell receptor mitigates the lethal coagulopathy of sepsis. Nature Medicine. 14: 648-55. PMID 18488037 DOI: 10.1038/Nm1760  0.629
2008 Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 453: 807-11. PMID 18432192 DOI: 10.1038/Nature06905  0.579
2008 Buchanan JT, Colvin KM, Vicknair MR, Patel SK, Timmer AM, Nizet V. Strain-associated virulence factors of Streptococcus iniae in hybrid-striped bass. Veterinary Microbiology. 131: 145-53. PMID 18406547 DOI: 10.1016/J.Vetmic.2008.02.027  0.816
2008 Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. Discovery of a widely distributed toxin biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 105: 5879-84. PMID 18375757 DOI: 10.1073/Pnas.0801338105  0.791
2008 Peyssonnaux C, Boutin AT, Zinkernagel AS, Datta V, Nizet V, Johnson RS. Critical role of HIF-1alpha in keratinocyte defense against bacterial infection. The Journal of Investigative Dermatology. 128: 1964-8. PMID 18323789 DOI: 10.1038/Jid.2008.27  0.787
2008 McNamara C, Zinkernagel AS, Macheboeuf P, Cunningham MW, Nizet V, Ghosh P. Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence. Science (New York, N.Y.). 319: 1405-8. PMID 18323455 DOI: 10.1126/Science.1154470  0.602
2008 Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science (New York, N.Y.). 319: 1391-4. PMID 18276850 DOI: 10.1126/Science.1153018  0.785
2008 Cogen AL, Nizet V, Gallo RL. Skin microbiota: A source of disease or defence? British Journal of Dermatology. 158: 442-455. PMID 18275522 DOI: 10.1111/J.1365-2133.2008.08437.X  0.323
2008 Park B, Nizet V, Liu GY. Role of Staphylococcus aureus catalase in niche competition against Streptococcus pneumoniae. Journal of Bacteriology. 190: 2275-8. PMID 18223076 DOI: 10.1128/Jb.00006-08  0.567
2008 Peyssonnaux C, Nizet V, Johnson RS. Role of the hypoxia inducible factors in iron metabolism Cell Cycle. 7: 28-32. PMID 18212530 DOI: 10.4161/Cc.7.1.5145  0.636
2008 Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, Nizet V, Doran KS. A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence Faseb Journal. 22: 1715-1724. PMID 18198218 DOI: 10.1096/Fj.07-093963  0.829
2008 Gillen CM, Courtney HS, Schulze K, Rohde M, Wilson MR, Timmer AM, Guzman CA, Nizet V, Chhatwal GS, Walker MJ. Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete. The Journal of Biological Chemistry. 283: 6359-66. PMID 18180300 DOI: 10.1074/Jbc.M706739200  0.771
2008 Zinkernagel AS, Peyssonnaux C, Johnson RS, Nizet V. Pharmacologic augmentation of hypoxia-inducible factor-1α with mimosine boosts the bactericidal capacity of phagocytes Journal of Infectious Diseases. 197: 214-217. PMID 18173364 DOI: 10.1086/524843  0.791
2008 Meluzzi D, Zheng WH, Hensler M, Nizet V, Dorrestein PC. Top-down mass spectrometry on low-resolution instruments: characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways. Bioorganic & Medicinal Chemistry Letters. 18: 3107-11. PMID 18006314 DOI: 10.1016/J.Bmcl.2007.10.104  0.714
2008 Hensler ME, Quach D, Hsieh CJ, Doran KS, Nizet V. CAMP factor is not essential for systemic virulence of Group B Streptococcus Microbial Pathogenesis. 44: 84-88. PMID 17870297 DOI: 10.1016/J.Micpath.2007.08.005  0.798
2008 Carland TM, Locke JB, Nizet V, Gerwick L. Transcriptional studies of a novel family of “short C1q” domain proteins in zebrafish The Faseb Journal. 22: 558-558. DOI: 10.1096/Fasebj.22.2_Supplement.558  0.659
2008 Maisey HC, Doran KS, Nizet V. Recent advances in understanding the molecular basis of group B Streptococcus virulence – CORRIGENDUM Expert Reviews in Molecular Medicine. 10. DOI: 10.1017/S1462399408000914  0.532
2008 Maisey HC, Doran KS, Nizet V. Recent advances in understanding the molecular basis of group B Streptococcus virulence Expert Reviews in Molecular Medicine. 10: 1-16. DOI: 10.1017/S1462399408000811  0.563
2007 Cole JN, Aquilina JA, Hains PG, Henningham A, Sriprakash KS, Caparon MG, Nizet V, Kotb M, Cordwell SJ, Djordjevic SP, Walker MJ. Role of group A Streptococcus HtrA in the maturation of SpeB protease. Proteomics. 7: 4488-98. PMID 18072207 DOI: 10.1002/Pmic.200700626  0.62
2007 Zinkernagel AS, Johnson RS, Nizet V. Hypoxia inducible factor (HIF) function in innate immunity and infection Journal of Molecular Medicine. 85: 1339-1346. PMID 18030436 DOI: 10.1007/S00109-007-0282-2  0.63
2007 Zinkernagel AS, Nizet V. Staphylococcus aureus: A Blemish on Skin Immunity Cell Host and Microbe. 1: 161-162. PMID 18005694 DOI: 10.1016/J.Chom.2007.05.003  0.656
2007 Locke JB, Colvin KM, Varki N, Vicknair MR, Nizet V, Buchanan JT. Streptococcus iniae beta-hemolysin streptolysin S is a virulence factor in fish infection. Diseases of Aquatic Organisms. 76: 17-26. PMID 17718161 DOI: 10.3354/Dao076017  0.806
2007 Kwinn LA, Nizet V. How group A Streptococcus circumvents host phagocyte defenses. Future Microbiology. 2: 75-84. PMID 17661677 DOI: 10.2217/17460913.2.1.75  0.456
2007 Lewis AL, Cao H, Patel SK, Diaz S, Ryan W, Carlin AF, Thon V, Lewis WG, Varki A, Chen X, Nizet V. NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus. The Journal of Biological Chemistry. 282: 27562-71. PMID 17646166 DOI: 10.1074/Jbc.M700340200  0.751
2007 Walker MJ, Hollands A, Sanderson-Smith ML, Cole JN, Kirk JK, Henningham A, McArthur JD, Dinkla K, Aziz RK, Kansal RG, Simpson AJ, Buchanan JT, Chhatwal GS, Kotb M, Nizet V. DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nature Medicine. 13: 981-5. PMID 17632528 DOI: 10.1038/Nm1612  0.824
2007 Bayele HK, Peyssonnaux C, Giatromanolaki A, Arrais-Silva WW, Mohamed HS, Collins H, Giorgio S, Koukourakis M, Johnson RS, Blackwell JM, Nizet V, Srai SK. HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite. Blood. 110: 3039-48. PMID 17606764 DOI: 10.1182/Blood-2006-12-063289  0.698
2007 Nizet V. Understanding how leading bacterial pathogens subvert innate immunity to reveal novel therapeutic targets Journal of Allergy and Clinical Immunology. 120: 13-22. PMID 17606031 DOI: 10.1016/J.Jaci.2007.06.005  0.482
2007 Peyssonnaux C, Zinkernagel AS, Schuepbach RA, Rankin E, Vaulont S, Haase VH, Nizet V, Johnson RS. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). The Journal of Clinical Investigation. 117: 1926-32. PMID 17557118 DOI: 10.1172/Jci31370  0.727
2007 Peyssonnaux C, Cejudo-Martin P, Doedens A, Zinkernagel AS, Johnson RS, Nizet V. Cutting edge: Essential role of hypoxia inducible factor-1α in development of lipopolysaccharide-induced sepsis Journal of Immunology. 178: 7516-7519. PMID 17548584 DOI: 10.4049/Jimmunol.178.12.7516  0.754
2007 Kristian SA, Timmer AM, Liu GY, Lauth X, Sal-Man N, Rosenfeld Y, Shai Y, Gallo RL, Nizet V. Impairment of innate immune killing mechanisms by bacteriostatic antibiotics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1107-16. PMID 17215486 DOI: 10.1096/Fj.06-6802Com  0.834
2007 Kwinn LA, Khosravi A, Aziz RK, Timmer AM, Doran KS, Kotb M, Nizet V. Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus. Journal of Bacteriology. 189: 1322-9. PMID 17114267 DOI: 10.1128/Jb.01256-06  0.816
2007 Locke JB, Colvin KM, Datta AK, Patel SK, Naidu NN, Neely MN, Nizet V, Buchanan JT. Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish. Journal of Bacteriology. 189: 1279-87. PMID 17098893 DOI: 10.1128/Jb.01175-06  0.801
2007 Maisey HC, Hensler M, Nizet V, Doran KS. Group B streptococcal pilus proteins contribute to adherence to and invasion of brain microvascular endothelial cells Journal of Bacteriology. 189: 1464-1467. PMID 17041051 DOI: 10.1128/Jb.01153-06  0.777
2007 Carlin AF, Lewis AL, Varki A, Nizet V. Group B streptococcal capsular sialic acids interact with siglecs (immunoglobulin-like lectins) on human leukocytes. Journal of Bacteriology. 189: 1231-7. PMID 16997964 DOI: 10.1128/Jb.01155-06  0.799
2006 Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, Junger WG. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science (New York, N.Y.). 314: 1792-5. PMID 17170310 DOI: 10.1126/Science.1132559  0.773
2006 Dehority W, Uchiyama S, Khosravi A, Nizet V. Brain abscess caused by streptococcus pyogenes in a previously healthy child Journal of Clinical Microbiology. 44: 4613-4615. PMID 17065264 DOI: 10.1128/Jcm.01724-06  0.633
2006 Hamilton A, Popham DL, Carl DJ, Lauth X, Nizet V, Jones AL. Penicillin-binding protein 1a promotes resistance of group B streptococcus to antimicrobial peptides. Infection and Immunity. 74: 6179-87. PMID 17057092 DOI: 10.1128/Iai.00895-06  0.839
2006 Hidalgo-Grass C, Mishalian I, Dan-Goor M, Belotserkovsky I, Eran Y, Nizet V, Peled A, Hanski E. A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues. The Embo Journal. 25: 4628-37. PMID 16977314 DOI: 10.1038/Sj.Emboj.7601327  0.432
2006 Timmer AM, Kristian SA, Datta V, Jeng A, Gillen CM, Walker MJ, Beall B, Nizet V. Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence. Molecular Microbiology. 62: 15-25. PMID 16942605 DOI: 10.1111/J.1365-2958.2006.05337.X  0.807
2006 Hensler ME, Bernstein G, Nizet V, Nefzi A. Pyrrolidine bis-cyclic guanidines with antimicrobial activity against drug-resistant Gram-positive pathogens identified from a mixture-based combinatorial library. Bioorganic & Medicinal Chemistry Letters. 16: 5073-9. PMID 16890437 DOI: 10.1016/J.Bmcl.2006.07.037  0.728
2006 Cole JN, McArthur JD, McKay FC, Sanderson-Smith ML, Cork AJ, Ranson M, Rohde M, Itzek A, Sun H, Ginsburg D, Kotb M, Nizet V, Chhatwal GS, Walker MJ. Trigger for group A streptococcal M1T1 invasive disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1745-7. PMID 16790522 DOI: 10.1096/Fj.06-5804Fje  0.638
2006 Karin M, Lawrence T, Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell. 124: 823-35. PMID 16497591 DOI: 10.1016/J.Cell.2006.02.016  0.378
2006 Lewis AL, Hensler ME, Varki A, Nizet V. The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters. The Journal of Biological Chemistry. 281: 11186-92. PMID 16490781 DOI: 10.1074/Jbc.M513772200  0.8
2006 Buchanan JT, Simpson AJ, Aziz RK, Liu GY, Kristian SA, Kotb M, Feramisco J, Nizet V. DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Current Biology : Cb. 16: 396-400. PMID 16488874 DOI: 10.1016/J.Cub.2005.12.039  0.845
2006 Nizet V. Antimicrobial peptide resistance mechanisms of human bacterial pathogens Current Issues in Molecular Biology. 8: 11-26. PMID 16450883  0.356
2006 Dorschner RA, Lopez-Garcia B, Peschel A, Kraus D, Morikawa K, Nizet V, Gallo RL. The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 35-42. PMID 16394265 DOI: 10.1096/Fj.05-4406Com  0.426
2006 Peyssonnaux C, Zinkernagel AS, Datta V, Lauth X, Johnson RS, Nizet V. TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood. 107: 3727-32. PMID 16391018 DOI: 10.1182/Blood-2005-06-2259  0.821
2006 Kristian SA, Datta V, Weidenmaier C, Kansal R, Fedtke I, Peschel A, Gallo RL, Nizet V. DltABCD-mediated d-alanylation of teichoic acids in Group A Streptococcus confers innate immune resistance International Congress Series. 1289: 254-256. DOI: 10.1016/j.ics.2006.01.074  0.827
2006 Timmer AM, Datta V, Kristian S, Jeng A, Beall B, Nizet V. The contribution of serum opacity factor to group A streptococcal epithelial cell invasion International Congress Series. 1289: 246-249. DOI: 10.1016/j.ics.2005.11.029  0.8
2006 Maisey HC, Hensler ME, Khosravi A, Liu GY, Nizet V, Doran KS. A single streptococcal gene can confer innate immune resistance and virulence to a nonpathogenic bacterium International Congress Series. 1289: 223-226. DOI: 10.1016/j.ics.2005.10.024  0.794
2006 Liu GY, Nizet V. The group B streptococcal β-hemolysin/cytolysin The Comprehensive Sourcebook of Bacterial Protein Toxins. 737-747. DOI: 10.1016/B978-012088445-2/50048-2  0.488
2005 Buchanan JT, Stannard JA, Lauth X, Ostland VE, Powell HC, Westerman ME, Nizet V. Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine development. Infection and Immunity. 73: 6935-44. PMID 16177373 DOI: 10.1128/Iai.73.10.6935-6944.2005  0.809
2005 Braff MH, Zaiou M, Fierer J, Nizet V, Gallo RL. Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens Infection and Immunity. 73: 6771-6781. PMID 16177355 DOI: 10.1128/Iai.73.10.6771-6781.2005  0.458
2005 Kristian SA, Datta V, Weidenmaier C, Kansal R, Fedtke I, Peschel A, Gallo RL, Nizet V. D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion. Journal of Bacteriology. 187: 6719-25. PMID 16166534 DOI: 10.1128/Jb.187.19.6719-6725.2005  0.833
2005 Doran KS, Engelson EJ, Khosravi A, Maisey HC, Fedtke I, Equils O, Michelsen KS, Arditi M, Peschel A, Nizet V. Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid. The Journal of Clinical Investigation. 115: 2499-507. PMID 16138192 DOI: 10.1172/Jci23829  0.603
2005 Georgel P, Crozat K, Lauth X, Makrantonaki E, Seltmann H, Sovath S, Hoebe K, Du X, Rutschmann S, Jiang Z, Bigby T, Nizet V, Zouboulis CC, Beutler B. A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria. Infection and Immunity. 73: 4512-21. PMID 16040962 DOI: 10.1128/Iai.73.8.4512-4521.2005  0.818
2005 Liu GY, Essex A, Buchanan JT, Datta V, Hoffman HM, Bastian JF, Fierer J, Nizet V. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity. The Journal of Experimental Medicine. 202: 209-15. PMID 16009720 DOI: 10.1084/Jem.20050846  0.793
2005 Peyssonnaux C, Datta V, Cramer T, Doedens A, Theodorakis EA, Gallo RL, Hurtado-Ziola N, Nizet V, Johnson RS. HIF-1alpha expression regulates the bactericidal capacity of phagocytes. The Journal of Clinical Investigation. 115: 1806-15. PMID 16007254 DOI: 10.1172/Jci23865  0.77
2005 Braff MH, Bardan A, Nizet V, Gallo RL. Cutaneous defense mechanisms by antimicrobial peptides. The Journal of Investigative Dermatology. 125: 9-13. PMID 15982297 DOI: 10.1111/J.0022-202X.2004.23587.X  0.373
2005 Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature. 434: 1138-43. PMID 15858576 DOI: 10.1038/Nature03491  0.51
2005 Datta V, Myskowski SM, Kwinn LA, Chiem DN, Varki N, Kansal RG, Kotb M, Nizet V. Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection. Molecular Microbiology. 56: 681-95. PMID 15819624 DOI: 10.1111/J.1365-2958.2005.04583.X  0.674
2005 Hensler ME, Liu GY, Sobczak S, Benirschke K, Nizet V, Heldt GP. Virulence role of group B Streptococcus β-hemolysin/cytolysin in a neonatal rabbit model of early-onset pulmonary infection Journal of Infectious Diseases. 191: 1287-1291. PMID 15776375 DOI: 10.1086/428946  0.765
2005 Lauth X, Babon JJ, Stannard JA, Singh S, Nizet V, Carlberg JM, Ostland VE, Pennington MW, Norton RS, Westerman ME. Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections. The Journal of Biological Chemistry. 280: 9272-82. PMID 15546886 DOI: 10.1074/Jbc.M411154200  0.823
2004 Doran KS, Nizet V. Molecular pathogenesis of neonatal group B streptococcal infection: No longer in its infancy Molecular Microbiology. 54: 23-31. PMID 15458402 DOI: 10.1111/J.1365-2958.2004.04266.X  0.618
2004 Liu GY, Doran KS, Lawrence T, Turkson N, Puliti M, Tissi L, Nizet V. Sword and shield: Linked group B streptococcal β-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense Proceedings of the National Academy of Sciences of the United States of America. 101: 14491-14496. PMID 15381763 DOI: 10.1073/Pnas.0406143101  0.705
2004 Lewis AL, Nizet V, Varki A. Discovery and characterization of sialic acid O-acetylation in group B Streptococcus. Proceedings of the National Academy of Sciences of the United States of America. 101: 11123-8. PMID 15263085 DOI: 10.1073/Pnas.0403010101  0.645
2004 Bardan A, Nizet V, Gallo RL. Antimicrobial peptides and the skin. Expert Opinion On Biological Therapy. 4: 543-9. PMID 15102603 DOI: 10.1517/14712598.4.4.543  0.398
2004 Hidalgo-Grass C, Dan-Goor M, Maly A, Eran Y, Kwinn LA, Nizet V, Ravins M, Jaffe J, Peyser A, Moses AE, Hanski E. Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections. Lancet (London, England). 363: 696-703. PMID 15001327 DOI: 10.1016/S0140-6736(04)15643-2  0.42
2004 Liu GYH, Nizet V. Extracellular virulence factors of group B streptococci Frontiers in Bioscience. 9: 1794-1802. PMID 14977587 DOI: 10.2741/1296  0.553
2004 Aziz RK, Pabst MJ, Jeng A, Kansal R, Low DE, Nizet V, Kotb M. Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB. Molecular Microbiology. 51: 123-34. PMID 14651616 DOI: 10.1046/J.1365-2958.2003.03797.X  0.781
2004 Cramer T, Peyssonnaux C, Johnson R, Nizet V, Wiedenmann B, Hoecker M. Der Transkriptionsfaktor HIF–1α ist ein essenzieller Regulator von inflammatorischen und antimikrobiellen Prozessen Zeitschrift FüR Gastroenterologie. 42. DOI: 10.1055/S-2004-831668  0.632
2003 Saitoh A, Beall B, Nizet V. Fulminant Bacterial Meningitis Complicating Sphenoid Sinusitis Pediatric Emergency Care. 19: 415-417. PMID 14676492 DOI: 10.1097/01.Pec.0000101584.65509.4B  0.323
2003 Nizet V, Gallo RL. Cathelicidins and innate defense against invasive bacterial infection Scandinavian Journal of Infectious Diseases. 35: 670-676. PMID 14620153 DOI: 10.1080/00365540310015629  0.44
2003 Doran KS, Liu GY, Nizet V. Group B streptococcal β-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis Journal of Clinical Investigation. 112: 736-744. PMID 12952922 DOI: 10.1172/Jci17335  0.689
2003 Gallo RL, Nizet V. Endogenous production of antimicrobial peptides in innate immunity and human disease Current Allergy and Asthma Reports. 3: 402-409. PMID 12906776 DOI: 10.1007/S11882-003-0074-X  0.373
2003 Kristian SA, Lauth X, Nizet V, Goetz F, Neumeister B, Peschel A, Landmann R. Alanylation of teichoic acids protects Staphylococcus aureus against Toll-like receptor 2-dependent host defense in a mouse tissue cage infection model. The Journal of Infectious Diseases. 188: 414-23. PMID 12870123 DOI: 10.1086/376533  0.824
2003 Zaiou M, Nizet V, Gallo RL. Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence Journal of Investigative Dermatology. 120: 810-816. PMID 12713586 DOI: 10.1046/J.1523-1747.2003.12132.X  0.411
2003 Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 112: 645-57. PMID 12628185 DOI: 10.1016/S0092-8674(03)00154-5  0.307
2003 Jeng A, Sakota V, Li Z, Datta V, Beall B, Nizet V. Molecular genetic analysis of a group A Streptococcus operon encoding serum opacity factor and a novel fibronectin-binding protein, SfbX. Journal of Bacteriology. 185: 1208-17. PMID 12562790 DOI: 10.1128/Jb.185.4.1208-1217.2003  0.799
2003 Kansal RG, Nizet V, Jeng A, Chuang WJ, Kotb M. Selective modulation of superantigen-induced responses by streptococcal cysteine protease Journal of Infectious Diseases. 187: 398-407. PMID 12552423 DOI: 10.1086/368022  0.761
2003 Nizet V. Response from Nizet: CylI and group B streptococcal hemolysis Trends in Microbiology. 11: 498. DOI: 10.1016/J.Tim.2003.09.007  0.305
2002 Nizet V. Streptococcal β-hemolysins: Genetics and role in disease pathogenesis Trends in Microbiology. 10: 575-580. PMID 12564994 DOI: 10.1016/S0966-842X(02)02473-3  0.384
2002 Ring A, Depnering C, Pohl J, Nizet V, Shenep JL, Stremmel W. Synergistic action of nitric oxide release from murine macrophages caused by group B streptococcal cell wall and β-hemolysin/cytolysin Journal of Infectious Diseases. 186: 1518-1521. PMID 12404173 DOI: 10.1086/344895  0.317
2002 Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT. Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways. Journal of Immunology (Baltimore, Md. : 1950). 169: 3970-7. PMID 12244198 DOI: 10.4049/Jimmunol.169.7.3970  0.354
2002 Fuller JD, Camus AC, Duncan CL, Nizet V, Bast DJ, Thune RL, Low DE, De Azavedo JC. Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infection and Immunity. 70: 5730-9. PMID 12228303 DOI: 10.1128/Iai.70.10.5730-5739.2002  0.402
2002 Ring A, Braun JS, Pohl J, Nizet V, Stremmel W, Shenep JL. Group B streptococcal β-hemolysin induces mortality and liver injury in experimental sepsis Journal of Infectious Diseases. 185: 1745-1753. PMID 12085320 DOI: 10.1086/340818  0.366
2002 Doran KS, Benoit VM, Gertz RE, Beall B, Nizet V. Late-onset group B streptococcal infection in identical twins: Insight to disease pathogenesis Journal of Perinatology. 22: 326-330. PMID 12032798 DOI: 10.1038/Sj.Jp.7210675  0.583
2002 Humar D, Datta V, Bast DJ, Beall B, De Azavedo JC, Nizet V. Streptolysin S and necrotising infections produced by group G streptococcus. Lancet (London, England). 359: 124-9. PMID 11809255 DOI: 10.1016/S0140-6736(02)07371-3  0.616
2002 Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V. Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. The Journal of Infectious Diseases. 185: 196-203. PMID 11807693 DOI: 10.1086/338475  0.688
2002 Lauth X, Shike H, Burns JC, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Nizet V, Taylor SW, Shimizu C, Bulet P. Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. The Journal of Biological Chemistry. 277: 5030-9. PMID 11739390 DOI: 10.1074/Jbc.M109173200  0.78
2001 Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith JA, Schromm AB, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT. Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. Journal of Immunology (Baltimore, Md. : 1950). 167: 7069-76. PMID 11739528 DOI: 10.4049/Jimmunol.167.12.7069  0.329
2001 Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, Pestonjamasp V, Piraino J, Huttner K, Gallo RL. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature. 414: 454-7. PMID 11719807 DOI: 10.1038/35106587  0.81
2001 Ballon-Landa GR, Gherardi G, Beall B, Krosner S, Nizet V. Necrotizing fasciitis due to penicillin-resistant Streptococcus pneumoniae: Case report and review of the literature Journal of Infection. 42: 272-277. PMID 11545571 DOI: 10.1053/Jinf.2000.0801  0.367
2001 Dorschner RA, Pestonjamasp VK, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, Agerberth B, Gudmundsson GH, Gallo RL. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A streptococcus Journal of Investigative Dermatology. 117: 91-97. PMID 11442754 DOI: 10.1046/J.1523-1747.2001.01340.X  0.388
2001 Fuller JD, Bast DJ, Nizet V, Low DE, De Azavedo JCS. Streptococcus iniae virulence is associated with a distinct genetic profile Infection and Immunity. 69: 1994-2000. PMID 11254550 DOI: 10.1128/Iai.69.4.1994-2000.2001  0.366
2001 Pritzlaff CA, Chang JCW, Kuo SP, Tamura GS, Rubens CE, Nizet V. Genetic basis for the β-haemolytic/cytolytic activity of group B streptococcus Molecular Microbiology. 39: 236-247. PMID 11136446 DOI: 10.1046/J.1365-2958.2001.02211.X  0.715
2000 Puliti M, Nizet V, Von Hunolstein C, Bistoni F, Mosci P, Orefici G, Tissi L. Severity of group B streptococcal arthritis is correlated with β-hemolysin expression Journal of Infectious Diseases. 182: 824-832. PMID 10950777 DOI: 10.1086/315773  0.364
2000 Ring A, Braun JS, Nizet V, Stremmel W, Shenep JL. Group B streptococcal β-hemolysin induces nitric oxide production in murine macrophages Journal of Infectious Diseases. 182: 150-157. PMID 10882592 DOI: 10.1086/315681  0.335
2000 Nizet V, Beall B, Bast DJ, Datta V, Kilburn L, Low DE, De Azavedo JC. Genetic locus for streptolysin S production by group A streptococcus. Infection and Immunity. 68: 4245-54. PMID 10858242 DOI: 10.1128/Iai.68.7.4245-4254.2000  0.649
2000 Charland N, Nizet V, Rubens CE, Kim KS, Lacouture S, Gottschalk M. Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells Infection and Immunity. 68: 637-643. PMID 10639427 DOI: 10.1128/Iai.68.2.637-643.2000  0.631
1999 Gibson RL, Nizet V, Rubens CE. Group B streptococcal β-hemolysin promotes injury of lung microvascular endothelial cells Pediatric Research. 45: 626-634. PMID 10231855 DOI: 10.1203/00006450-199905010-00003  0.592
1998 Nizet V, Smith AL, Sullam PM, Rubens CE. A simple microtiter plate screening assay for bacterial invasion or adherence Methods in Cell Science. 20: 107-111. DOI: 10.1023/A:1009830606819  0.628
1997 Nizet V, Kim KS, Stins M, Jonas M, Chi EY, Nguyen D, Rubens CE. Invasion of brain microvascular endothelial cells by group B streptococci Infection and Immunity. 65: 5074-5081. PMID 9393798 DOI: 10.1128/Iai.65.12.5074-5081.1997  0.62
1997 La Penta D, Framson P, Nizet V, Rubens C. Epithelial cell invasion by Group B streptococci is important to virulence Advances in Experimental Medicine and Biology. 418: 631-634. PMID 9331731 DOI: 10.1007/978-1-4899-1825-3_147  0.627
1997 Nizet V, Gibson RL, Rubens CE. The role of Group B streptococci β-hemolysin expression in newborn lung injury Advances in Experimental Medicine and Biology. 418: 627-630. PMID 9331730 DOI: 10.1007/978-1-4899-1825-3_146  0.582
1996 Mills WJ, Mosca VS, Nizet V. Orthopaedic manifestations of invasive group A streptococcal infections complicating primary varicella Journal of Pediatric Orthopaedics. 16: 522-528. PMID 8784712 DOI: 10.1097/00004694-199607000-00021  0.336
1996 Nizet V, Gibson RL, Chi EY, Framson PE, Hulse M, Rubens CE. Group B streptococcal beta-hemolysin expression is associated with injury of lung epithelial cells Infection and Immunity. 64: 3818-3826. PMID 8751934 DOI: 10.1128/Iai.64.9.3818-3826.1996  0.585
1996 Nizet V, Colina KF, Almquist JR, Rubens CE, Smith AL. A virulent nonencapsulated Haemophilus influenzae Journal of Infectious Diseases. 173: 180-186. PMID 8537657 DOI: 10.1093/Infdis/173.1.180  0.676
1996 Nizet V, Gibson RL, Rubens CE. GROUP B STREPTOCCAL β-HEMOLYSIN EXPRESSION AND INJURY OF NEWBORN LUNG.• 1781 Pediatric Research. 39: 299-299. DOI: 10.1203/00006450-199604001-01805  0.54
1996 Brogan TV, Nizet V, Waldhausen JHT, Rubens CE, Clarke WR. IN REPLY: VARICELLA AND NECROTIZING FASCIITIS The Pediatric Infectious Disease Journal. 15: 556-557. DOI: 10.1097/00006454-199606000-00025  0.555
1995 Brogan TV, Nizet V, Waldhausen JH, Rubens CE, Clarke WR. Group A streptococcal necrotizing fasciitis complicating primary varicella: a series of fourteen patients. The Pediatric Infectious Disease Journal. 14: 588-94. PMID 7567287 DOI: 10.1097/00006454-199507000-00007  0.568
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