Alexander Mankin - Publications

University of Illinois at Chicago, Health Sciences Center 
Microbiology Biology

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Svetlov MS, Koller TO, Meydan S, Shankar V, Klepacki D, Polacek N, Guydosh NR, Vázquez-Laslop N, Wilson DN, Mankin AS. Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Nature Communications. 12: 2803. PMID 33990576 DOI: 10.1038/s41467-021-23068-1  0.52
2021 Meydan S, Klepacki D, Mankin AS, Vázquez-Laslop N. Identification of Translation Start Sites in Bacterial Genomes. Methods in Molecular Biology (Clifton, N.J.). 2252: 27-55. PMID 33765270 DOI: 10.1007/978-1-0716-1150-0_2  0.52
2021 Baliga C, Brown TJ, Florin T, Colon S, Shah V, Skowron KJ, Kefi A, Szal T, Klepacki D, Moore TW, Vázquez-Laslop N, Mankin AS. Charting the sequence-activity landscape of peptide inhibitors of translation termination. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33674389 DOI: 10.1073/pnas.2026465118  0.52
2020 Mangano K, Florin T, Shao X, Klepacki D, Chelysheva I, Ignatova Z, Gao Y, Mankin AS, Vázquez-Laslop N. Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria. Elife. 9. PMID 33031031 DOI: 10.7554/eLife.62655  0.52
2020 Ovchinnikov SV, Bikmetov D, Livenskyi A, Serebryakova M, Wilcox B, Mangano K, Shiriaev DI, Osterman IA, Sergiev PV, Borukhov S, Vazquez-Laslop N, Mankin AS, Severinov K, Dubiley S. Mechanism of translation inhibition by type II GNAT toxin AtaT2. Nucleic Acids Research. PMID 32597957 DOI: 10.1093/nar/gkaa551  0.32
2020 Huang S, Aleksashin NA, Loveland AB, Klepacki D, Reier K, Kefi A, Szal T, Remme J, Jaeger L, Vázquez-Laslop N, Korostelev AA, Mankin AS. Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly. Nature Communications. 11: 2900. PMID 32518240 DOI: 10.1038/S41467-020-16694-8  0.52
2020 Aleksashin NA, Szal T, d'Aquino AE, Jewett MC, Vázquez-Laslop N, Mankin AS. A fully orthogonal system for protein synthesis in bacterial cells. Nature Communications. 11: 1858. PMID 32313034 DOI: 10.1038/S41467-020-15756-1  0.52
2020 Svetlov MS, Cohen S, Alsuhebany N, Vázquez-Laslop N, Mankin AS. A long-distance rRNA base pair impacts the ability of macrolide antibiotics to kill bacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 31932436 DOI: 10.1073/pnas.1918948117  0.52
2019 Choi J, Marks J, Zhang J, Chen DH, Wang J, Vázquez-Laslop N, Mankin AS, Puglisi JD. Dynamics of the context-specific translation arrest by chloramphenicol and linezolid. Nature Chemical Biology. PMID 31844301 DOI: 10.1038/s41589-019-0423-2  0.52
2019 Carlson ED, d'Aquino AE, Kim DS, Fulk EM, Hoang K, Szal T, Mankin AS, Jewett MC. Engineered ribosomes with tethered subunits for expanding biological function. Nature Communications. 10: 3920. PMID 31477696 DOI: 10.1038/S41467-019-11427-Y  0.52
2019 Meydan S, Marks J, Klepacki D, Sharma V, Baranov PV, Firth AE, Margus T, Kefi A, Vázquez-Laslop N, Mankin AS. Retapamulin-Assisted Ribosome Profiling Reveals the Alternative Bacterial Proteome. Molecular Cell. PMID 30904393 DOI: 10.1016/j.molcel.2019.02.017  0.52
2019 Aleksashin NA, Leppik M, Hockenberry AJ, Klepacki D, Vázquez-Laslop N, Jewett MC, Remme J, Mankin AS. Assembly and functionality of the ribosome with tethered subunits. Nature Communications. 10: 930. PMID 30804338 DOI: 10.1038/S41467-019-08892-W  0.52
2018 Vázquez-Laslop N, Mankin AS. How Macrolide Antibiotics Work. Trends in Biochemical Sciences. PMID 30054232 DOI: 10.1016/j.tibs.2018.06.011  0.52
2018 Meydan S, Vázquez-Laslop N, Mankin AS. Genes within Genes in Bacterial Genomes. Microbiology Spectrum. 6. PMID 30003865 DOI: 10.1128/microbiolspec.RWR-0020-2018  0.52
2018 Vázquez-Laslop N, Mankin AS. Context-Specific Action of Ribosomal Antibiotics. Annual Review of Microbiology. PMID 29906204 DOI: 10.1146/annurev-micro-090817-062329  0.52
2018 Tereshchenkov AG, Dobosz-Bartoszek M, Osterman IA, Marks J, Sergeeva VA, Kasatsky P, Komarova ES, Stavrianidi AA, Rodin IA, Konevega AL, Sergiev PV, Sumbatyan NV, Mankin AS, Bogdanov AA, Polikanov YS. Binding and action of amino-acid analogues of chloramphenicol upon the bacterial ribosome. Journal of Molecular Biology. PMID 29410130 DOI: 10.1016/j.jmb.2018.01.016  0.32
2017 Svetlov MS, Vázquez-Laslop N, Mankin AS. Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 114: 13673-13678. PMID 29229833 DOI: 10.1073/pnas.1717168115  0.52
2017 Almutairi MM, Svetlov MS, Hansen DA, Khabibullina NF, Klepacki D, Kang HY, Sherman DH, Vázquez-Laslop N, Polikanov YS, Mankin AS. Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins. Nucleic Acids Research. 45: 9573-9582. PMID 28934499 DOI: 10.1093/Nar/Gkx673  0.52
2017 Florin T, Maracci C, Graf M, Karki P, Klepacki D, Berninghausen O, Beckmann R, Vázquez-Laslop N, Wilson DN, Rodnina MV, Mankin AS. An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome. Nature Structural & Molecular Biology. PMID 28741611 DOI: 10.1038/Nsmb.3439  0.52
2017 Meydan S, Klepacki D, Karthikeyan S, Margus T, Thomas P, Jones JE, Khan Y, Briggs J, Dinman JD, Vázquez-Laslop N, Mankin AS. Programmed Ribosomal Frameshifting Generates a Copper Transporter and a Copper Chaperone from the Same Gene. Molecular Cell. 65: 207-219. PMID 28107647 DOI: 10.1016/J.Molcel.2016.12.008  0.52
2016 Marks J, Kannan K, Roncase EJ, Klepacki D, Kefi A, Orelle C, Vázquez-Laslop N, Mankin AS. Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center. Proceedings of the National Academy of Sciences of the United States of America. 113: 12150-12155. PMID 27791002 DOI: 10.1073/pnas.1613055113  0.52
2016 Sothiselvam S, Neuner S, Rigger L, Klepacki D, Micura R, Vázquez-Laslop N, Mankin AS. Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size. Cell Reports. PMID 27498876 DOI: 10.1016/J.Celrep.2016.07.018  0.52
2016 Gupta P, Liu B, Klepacki D, Gupta V, Schulten K, Mankin AS, Vázquez-Laslop N. Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. Nature Chemical Biology. PMID 26727240 DOI: 10.1038/nchembio.1998  0.52
2015 Almutairi MM, Park SR, Rose S, Hansen DA, Vázquez-Laslop N, Douthwaite S, Sherman DH, Mankin AS. Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438831 DOI: 10.1073/Pnas.1512090112  1
2015 Orelle C, Carlson ED, Szal T, Florin T, Jewett MC, Mankin AS. Protein synthesis by ribosomes with tethered subunits. Nature. 524: 119-24. PMID 26222032 DOI: 10.1038/Nature14862  0.52
2015 Orelle C, Carlson ED, Szal T, Florin T, Jewett MC, Mankin AS. Protein synthesis by ribosomes with tethered subunits Nature. 524: 119-124. DOI: 10.1038/nature14862  1
2014 Kannan K, Kanabar P, Schryer D, Florin T, Oh E, Bahroos N, Tenson T, Weissman JS, Mankin AS. The general mode of translation inhibition by macrolide antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 111: 15958-63. PMID 25349425 DOI: 10.1073/Pnas.1417334111  1
2014 Polikanov YS, Szal T, Jiang F, Gupta P, Matsuda R, Shiozuka M, Steitz TA, Vázquez-Laslop N, Mankin AS. Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA. Molecular Cell. 56: 541-50. PMID 25306922 DOI: 10.1016/J.Molcel.2014.09.021  1
2014 Polikanov YS, Osterman IA, Szal T, Tashlitsky VN, Serebryakova MV, Kusochek P, Bulkley D, Malanicheva IA, Efimenko TA, Efremenkova OV, Konevega AL, Shaw KJ, Bogdanov AA, Rodnina MV, Dontsova OA, ... Mankin AS, et al. Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Molecular Cell. 56: 531-40. PMID 25306919 DOI: 10.1016/J.Molcel.2014.09.020  1
2014 Sothiselvam S, Liu B, Han W, Ramu H, Klepacki D, Atkinson GC, Brauer A, Remm M, Tenson T, Schulten K, Vázquez-Laslop N, Mankin AS. Macrolide antibiotics allosterically predispose the ribosome for translation arrest. Proceedings of the National Academy of Sciences of the United States of America. 111: 9804-9. PMID 24961372 DOI: 10.1073/Pnas.1403586111  1
2014 Vázquez-Laslop N, Mankin AS. Protein accounting in the cellular economy. Cell. 157: 529-31. PMID 24766801 DOI: 10.1016/j.cell.2014.04.002  0.52
2014 Arenz S, Ramu H, Gupta P, Berninghausen O, Beckmann R, Vázquez-Laslop N, Mankin AS, Wilson DN. Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide. Nature Communications. 5: 3501. PMID 24662426 DOI: 10.1038/Ncomms4501  0.52
2014 Martínez AK, Gordon E, Sengupta A, Shirole N, Klepacki D, Martinez-Garriga B, Brown LM, Benedik MJ, Yanofsky C, Mankin AS, Vazquez-Laslop N, Sachs MS, Cruz-Vera LR. Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan. Nucleic Acids Research. 42: 1245-56. PMID 24137004 DOI: 10.1093/nar/gkt923  1
2013 Gupta P, Kannan K, Mankin AS, Vázquez-Laslop N. Regulation of gene expression by macrolide-induced ribosomal frameshifting. Molecular Cell. 52: 629-42. PMID 24239289 DOI: 10.1016/j.molcel.2013.10.013  0.52
2013 Orelle C, Carlson S, Kaushal B, Almutairi MM, Liu H, Ochabowicz A, Quan S, Pham VC, Squires CL, Murphy BT, Mankin AS. Tools for characterizing bacterial protein synthesis inhibitors. Antimicrobial Agents and Chemotherapy. 57: 5994-6004. PMID 24041905 DOI: 10.1128/Aac.01673-13  1
2013 Orelle C, Szal T, Klepacki D, Shaw KJ, Vázquez-Laslop N, Mankin AS. Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition. Nucleic Acids Research. 41: e144. PMID 23761439 DOI: 10.1093/nar/gkt526  0.52
2013 Gupta P, Sothiselvam S, Vázquez-Laslop N, Mankin AS. Deregulation of translation due to post-transcriptional modification of rRNA explains why erm genes are inducible. Nature Communications. 4: 1984. PMID 23749080 DOI: 10.1038/ncomms2984  0.52
2013 LaMarre J, Mendes RE, Szal T, Schwarz S, Jones RN, Mankin AS. The genetic environment of the cfr gene and the presence of other mechanisms account for the very high linezolid resistance of Staphylococcus epidermidis isolate 426-3147L. Antimicrobial Agents and Chemotherapy. 57: 1173-9. PMID 23254434 DOI: 10.1128/AAC.02047-12  1
2012 Kannan K, Vázquez-Laslop N, Mankin AS. Selective protein synthesis by ribosomes with a drug-obstructed exit tunnel. Cell. 151: 508-20. PMID 23101624 DOI: 10.1016/j.cell.2012.09.018  0.52
2012 LeTourneau N, Vimal P, Klepacki D, Mankin A, Melman A. Synthesis and antibacterial activity of desosamine-modified macrolide derivatives. Bioorganic & Medicinal Chemistry Letters. 22: 4575-8. PMID 22738632 DOI: 10.1016/J.Bmcl.2012.05.110  1
2012 Locke JB, Rahawi S, Lamarre J, Mankin AS, Shaw KJ. Genetic environment and stability of cfr in methicillin-resistant Staphylococcus aureus CM05. Antimicrobial Agents and Chemotherapy. 56: 332-40. PMID 22024827 DOI: 10.1128/AAC.05420-11  1
2011 Shearer JE, Wireman J, Hostetler J, Forberger H, Borman J, Gill J, Sanchez S, Mankin A, Lamarre J, Lindsay JA, Bayles K, Nicholson A, O'Brien F, Jensen SO, Firth N, et al. Major families of multiresistant plasmids from geographically and epidemiologically diverse staphylococci. G3 (Bethesda, Md.). 1: 581-91. PMID 22384369 DOI: 10.1534/G3.111.000760  1
2011 Kannan K, Mankin AS. Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action. Annals of the New York Academy of Sciences. 1241: 33-47. PMID 22191525 DOI: 10.1111/j.1749-6632.2011.06315.x  1
2011 Vázquez-Laslop N, Klepacki D, Mulhearn DC, Ramu H, Krasnykh O, Franzblau S, Mankin AS. Role of antibiotic ligand in nascent peptide-dependent ribosome stalling. Proceedings of the National Academy of Sciences of the United States of America. 108: 10496-501. PMID 21670252 DOI: 10.1073/Pnas.1103474108  0.52
2011 LaMarre JM, Locke JB, Shaw KJ, Mankin AS. Low fitness cost of the multidrug resistance gene cfr. Antimicrobial Agents and Chemotherapy. 55: 3714-9. PMID 21646483 DOI: 10.1128/AAC.00153-11  1
2011 Vázquez-Laslop N, Mankin AS. Picky nascent peptides do not talk to foreign ribosomes. Proceedings of the National Academy of Sciences of the United States of America. 108: 5931-2. PMID 21464303 DOI: 10.1073/pnas.1103011108  0.52
2011 LaMarre JM, Howden BP, Mankin AS. Inactivation of the indigenous methyltransferase RlmN in Staphylococcus aureus increases linezolid resistance. Antimicrobial Agents and Chemotherapy. 55: 2989-91. PMID 21444696 DOI: 10.1128/AAC.00183-11  1
2011 Ramu H, Vázquez-Laslop N, Klepacki D, Dai Q, Piccirilli J, Micura R, Mankin AS. Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center. Molecular Cell. 41: 321-30. PMID 21292164 DOI: 10.1016/J.Molcel.2010.12.031  1
2010 Dunkle JA, Xiong L, Mankin AS, Cate JH. Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proceedings of the National Academy of Sciences of the United States of America. 107: 17152-7. PMID 20876128 DOI: 10.1073/Pnas.1007988107  1
2010 Llano-Sotelo B, Dunkle J, Klepacki D, Zhang W, Fernandes P, Cate JH, Mankin AS. Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrobial Agents and Chemotherapy. 54: 4961-70. PMID 20855725 DOI: 10.1128/Aac.00860-10  1
2010 Vázquez-Laslop N, Ramu H, Klepacki D, Kannan K, Mankin AS. The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide. The Embo Journal. 29: 3108-17. PMID 20676057 DOI: 10.1038/emboj.2010.180  0.52
2010 Auerbach T, Mermershtain I, Davidovich C, Bashan A, Belousoff M, Wekselman I, Zimmerman E, Xiong L, Klepacki D, Arakawa K, Kinashi H, Mankin AS, Yonath A. The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 107: 1983-8. PMID 20080686 DOI: 10.1073/Pnas.0914100107  0.52
2009 Llano-Sotelo B, Klepacki D, Mankin AS. Selection of small peptides, inhibitors of translation. Journal of Molecular Biology. 391: 813-9. PMID 19576904 DOI: 10.1016/j.jmb.2009.06.069  0.52
2009 Llano-Sotelo B, Hickerson RP, Lancaster L, Noller HF, Mankin AS. Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding Rna. 15: 1597-1604. PMID 19553343 DOI: 10.1261/Rna.1681609  1
2009 Siibak T, Peil L, Xiong L, Mankin A, Remme J, Tenson T. Erythromycin- and chloramphenicol-induced ribosomal assembly defects are secondary effects of protein synthesis inhibition. Antimicrobial Agents and Chemotherapy. 53: 563-71. PMID 19029332 DOI: 10.1128/Aac.00870-08  0.52
2008 Toh SM, Mankin AS. An indigenous posttranscriptional modification in the ribosomal peptidyl transferase center confers resistance to an array of protein synthesis inhibitors. Journal of Molecular Biology. 380: 593-7. PMID 18554609 DOI: 10.1016/J.Jmb.2008.05.027  1
2008 Mankin AS, Polacek N. SPARK: a new peptidyl transferase activity assay. Methods in Molecular Medicine. 142: 107-16. PMID 18437309 DOI: 10.1007/978-1-59745-246-5_9  0.4
2008 Smith LK, Mankin AS. Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. Antimicrobial Agents and Chemotherapy. 52: 1703-12. PMID 18299405 DOI: 10.1128/AAC.01583-07  1
2008 Samant S, Lee H, Ghassemi M, Chen J, Cook JL, Mankin AS, Neyfakh AA. Nucleotide biosynthesis is critical for growth of bacteria in human blood. Plos Pathogens. 4: e37. PMID 18282099 DOI: 10.1371/Journal.Ppat.0040037  1
2008 Toh SM, Xiong L, Bae T, Mankin AS. The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA. Rna (New York, N.Y.). 14: 98-106. PMID 18025251 DOI: 10.1261/Rna.814408  1
2007 Yassin A, Mankin AS. Potential new antibiotic sites in the ribosome revealed by deleterious mutations in RNA of the large ribosomal subunit. The Journal of Biological Chemistry. 282: 24329-42. PMID 17591769 DOI: 10.1074/Jbc.M703106200  1
2007 Toh SM, Xiong L, Arias CA, Villegas MV, Lolans K, Quinn J, Mankin AS. Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid. Molecular Microbiology. 64: 1506-14. PMID 17555436 DOI: 10.1111/j.1365-2958.2007.05744.x  1
2007 Leach KL, Swaney SM, Colca JR, McDonald WG, Blinn JR, Thomasco LM, Gadwood RC, Shinabarger D, Xiong L, Mankin AS. The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria. Molecular Cell. 26: 393-402. PMID 17499045 DOI: 10.1016/J.Molcel.2007.04.005  1
2006 Tenson T, Mankin A. Antibiotics and the ribosome. Molecular Microbiology. 59: 1664-77. PMID 16553874 DOI: 10.1111/J.1365-2958.2006.05063.X  0.4
2006 Sherman D, Xiong L, Mankin AS, Melman A. Synthesis and biological investigation of new 4''-malonyl tethered derivatives of erythromycin and clarithromycin. Bioorganic & Medicinal Chemistry Letters. 16: 1506-9. PMID 16387493 DOI: 10.1016/j.bmcl.2005.12.033  1
2005 Maguire BA, Beniaminov AD, Ramu H, Mankin AS, Zimmermann RA. A protein component at the heart of an RNA machine: the importance of protein l27 for the function of the bacterial ribosome. Molecular Cell. 20: 427-35. PMID 16285924 DOI: 10.1016/J.Molcel.2005.09.009  1
2005 Yassin A, Fredrick K, Mankin AS. Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 102: 16620-5. PMID 16269538 DOI: 10.1073/Pnas.0508444102  1
2005 Polacek N, Mankin AS. The ribosomal peptidyl transferase center: structure, function, evolution, inhibition. Critical Reviews in Biochemistry and Molecular Biology. 40: 285-311. PMID 16257828 DOI: 10.1080/10409230500326334  0.4
2005 Beringer M, Bruell C, Xiong L, Pfister P, Bieling P, Katunin VI, Mankin AS, Böttger EC, Rodnina MV. Essential mechanisms in the catalysis of peptide bond formation on the ribosome. The Journal of Biological Chemistry. 280: 36065-72. PMID 16129670 DOI: 10.1074/jbc.M507961200  0.4
2005 Erlacher MD, Lang K, Shankaran N, Wotzel B, Hüttenhofer A, Micura R, Mankin AS, Polacek N. Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451. Nucleic Acids Research. 33: 1618-27. PMID 15767286 DOI: 10.1093/Nar/Gki308  1
2005 Xiong L, Korkhin Y, Mankin AS. Binding site of the bridged macrolides in the Escherichia coli ribosome. Antimicrobial Agents and Chemotherapy. 49: 281-8. PMID 15616307 DOI: 10.1128/AAC.49.1.281-288.2005  0.4
2004 Vimberg V, Xiong L, Bailey M, Tenson T, Mankin A. Peptide-mediated macrolide resistance reveals possible specific interactions in the nascent peptide exit tunnel. Molecular Microbiology. 54: 376-85. PMID 15469510 DOI: 10.1111/J.1365-2958.2004.04290.X  0.4
2003 Colca JR, McDonald WG, Waldon DJ, Thomasco LM, Gadwood RC, Lund ET, Cavey GS, Mathews WR, Adams LD, Cecil ET, Pearson JD, Bock JH, Mott JE, Shinabarger DL, Xiong L, ... Mankin AS, et al. Cross-linking in the living cell locates the site of action of oxazolidinone antibiotics. The Journal of Biological Chemistry. 278: 21972-9. PMID 12690106 DOI: 10.1074/Jbc.M302109200  1
2003 Gaynor M, Mankin AS. Macrolide antibiotics: binding site, mechanism of action, resistance. Current Topics in Medicinal Chemistry. 3: 949-61. PMID 12678831  0.4
2003 Polacek N, Gomez MJ, Ito K, Xiong L, Nakamura Y, Mankin A. The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination. Molecular Cell. 11: 103-12. PMID 12535525 DOI: 10.1016/S1097-2765(02)00825-0  0.4
2002 Polacek N, Swaney S, Shinabarger D, Mankin AS. SPARK--a novel method to monitor ribosomal peptidyl transferase activity. Biochemistry. 41: 11602-10. PMID 12269803  0.4
2001 Garza-Ramos G, Xiong L, Zhong P, Mankin A. Binding Site of Macrolide Antibiotics on the Ribosome: New Resistance Mutation Identifies a Specific Interaction of Ketolides with rRNA Journal of Bacteriology. 183: 6898-6907. PMID 11698379 DOI: 10.1128/Jb.183.23.6898-6907.2001  0.4
2001 Mann PA, Xiong L, Mankin AS, Chau AS, Mendrick CA, Najarian DJ, Cramer CA, Loebenberg D, Coates E, Murgolo NJ, Aarestrup FM, Goering RV, Black TA, Hare RS, McNicholas PM. EmtA, a rRNA methyltransferase conferring high-level evernimicin resistance. Molecular Microbiology. 41: 1349-56. PMID 11580839 DOI: 10.1046/j.1365-2958.2001.02602.x  1
2001 Polacek N, Gaynor M, Yassin A, Mankin AS. Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide. Nature. 411: 498-501. PMID 11373685 DOI: 10.1038/35078113  1
2001 Bocchetta M, Xiong L, Shah S, Mankin AS. Interactions between 23S rRNA and tRNA in the ribosomal E site Rna. 7: 54-63. PMID 11214181 DOI: 10.1017/S1355838201001650  1
2001 Xiong L, Polacek N, Sander P, Böttger EC, Mankin A. pKa of adenine 2451 in the ribosomal peptidyl transferase center remains elusive. Rna. 7: 1365-1369. DOI: 10.5167/Uzh-4589  0.4
2000 Velichutina IV, Dresios J, Hong JY, Li C, Mankin A, Synetos D, Liebman SW. Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome. Rna (New York, N.Y.). 6: 1174-84. PMID 10943896 DOI: 10.1017/S1355838200000637  1
1999 Mankin AS, Liebman SW. Baby, don't stop! Nature Genetics. 23: 8-10. PMID 10471486 DOI: 10.1038/12600  1
1999 Chernyaeva NS, Murgola EJ, Mankin AS. Suppression of nonsense mutations induced by expression of an RNA complementary to a conserved segment of 23S rRNA Journal of Bacteriology. 181: 5257-5262. PMID 10464195 DOI: 10.1128/jb.181.17.5257-5262.1999  1
1999 Khaitovich P, Tenson T, Mankin AS, Green R. Peptidyl transferase activity catalyzed by protein-free 23S ribosomal RNA remains elusive [1] Rna. 5: 605-608. PMID 10334329 DOI: 10.1017/S1355838299990295  1
1999 Khaitovich P, Mankin AS, Green R, Lancaster L, Noller HF. Characterization of functionally active subribosomal particles from Thermus aquaticus. Proceedings of the National Academy of Sciences of the United States of America. 96: 85-90. PMID 9874776 DOI: 10.1073/Pnas.96.1.85  1
1998 Bocchetta M, Xiong L, Mankin AS. 23S rRNA positions essential for tRNA binding in ribosomal functional sites Proceedings of the National Academy of Sciences of the United States of America. 95: 3525-3530. PMID 9520399 DOI: 10.1073/Pnas.95.7.3525  1
1995 Noller HF, Green R, Heilek G, Hoffarth V, Hüttenhofer A, Joseph S, Lee I, Lieberman K, Mankin A, Merryman C. Structure and function of ribosomal RNA. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 997-1009. PMID 8722015 DOI: 10.1139/O95-107  1
1994 Leviev IG, Rodriguez-Fonseca C, Phan H, Garrett RA, Heilek G, Noller HF, Mankin AS. A conserved secondary structural motif in 23S rRNA defines the site of interaction of amicetin, a universal inhibitor of peptide bond formation. The Embo Journal. 13: 1682-6. PMID 8157007 DOI: 10.1002/J.1460-2075.1994.Tb06432.X  1
1985 Zueva VS, Mankin AS, Bogdanov AA, Thurlow DL, Zimmermann RA. Occurrence and location of 7-methylguanine residues in small-subunit ribosomal RNAs from eubacteria, archaebacteria and eukaryotes Febs Letters. 188: 233-238. DOI: 10.1016/0014-5793(85)80378-1  1
1984 Kozlov YV, Rupasov VV, Adyshev DM, Belgelarskaya SN, Agranovsky AA, Mankin AS, Morozov SY, Dolja VV, Atabekov JG. Nucleotide sequence of the 3′-terminal tRNA-like structure in barley stripe mosaic virus genome Nucleic Acids Research. 12: 4001-4009. PMID 6328450 DOI: 10.1093/Nar/12.9.4001  1
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