Raphael H. Valdivia - Publications

Affiliations: 
Genetics and Genomics Duke University, Durham, NC 
Area:
Microbiology Biology

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Yanatori I, Miura K, Chen YS, Valdivia RH, Kishi F. Application of a expression system to identify proteins translocated into host cells. Journal of Bacteriology. PMID 33685970 DOI: 10.1128/JB.00511-20  0.44
2021 McCann JR, Bihlmeyer NA, Roche K, Catherine C, Jawahar J, Kwee LC, Younge NE, Silverman J, Ilkayeva O, Sarria C, Zizzi A, Wootton J, Poppe L, Anderson P, Arlotto M, ... ... Valdivia RH, et al. The Pediatric Obesity Microbiome and Metabolism Study (POMMS): Methods, Baseline Data, and Early Insights. Obesity (Silver Spring, Md.). 29: 569-578. PMID 33624438 DOI: 10.1002/oby.23081  0.32
2019 Dudiak BM, Maksimchuk KR, Bednar MM, Podracky CJ, Burg JM, Nguyen TM, Nwogbo FO, Valdivia RH, McCafferty DG. Insights into the Autoproteolytic Processing and Catalytic Mechanism of the Virulence-Associated Protease CPAF. Biochemistry. PMID 31386347 DOI: 10.1021/Acs.Biochem.9B00522  0.44
2019 Panzetta ME, Luján AL, Bastidas RJ, Damiani MT, Valdivia RH, Saka HA. Ptr/CTL0175 Is Required for the Efficient Recovery of From Stress Induced by Gamma-Interferon. Frontiers in Microbiology. 10: 756. PMID 31024512 DOI: 10.3389/Fmicb.2019.00756  0.44
2018 Panzetta ME, Valdivia RH, Saka HA. Persistence: A Survival Strategy to Evade Antimicrobial Effects and . Frontiers in Microbiology. 9: 3101. PMID 30619180 DOI: 10.3389/Fmicb.2018.03101  0.44
2018 Pruneda JN, Bastidas RJ, Bertsoulaki E, Swatek KN, Santhanam B, Clague MJ, Valdivia RH, Urbé S, Komander D. A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation. Nature Microbiology. PMID 30397340 DOI: 10.2210/Pdb6Gzt/Pdb  0.44
2018 Valdivia RH, Bastidas RJ. THE EXPANDING MOLECULAR GENETICS TOOLKIT IN . Journal of Bacteriology. PMID 30297356 DOI: 10.1128/Jb.00590-18  0.44
2017 Mojica SA, Salin O, Bastidas RJ, Sunduru N, Hedenström M, Andersson CD, Otero CN, Engström P, Valdivia RH, Elofsson M, Gylfe Å. N-acylated derivatives of sulfamethoxazole block Chlamydia fatty acid synthesis and interact with FabF. Antimicrobial Agents and Chemotherapy. PMID 28784680 DOI: 10.1128/Aac.00716-17  0.44
2017 Carpenter V, Chen YS, Dolat L, Valdivia RH. The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles. Msphere. 2. PMID 28744480 DOI: 10.1128/mSphere.00207-17  0.44
2016 Sixt BS, Bastidas RJ, Finethy R, Baxter RM, Carpenter VK, Kroemer G, Coers J, Valdivia RH. The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs. Cell Host & Microbe. PMID 28041929 DOI: 10.1016/J.Chom.2016.12.002  0.44
2016 Bastidas RJ, Valdivia RH. Emancipating Chlamydia: Advances in the Genetic Manipulation of a Recalcitrant Intracellular Pathogen. Microbiology and Molecular Biology Reviews : Mmbr. 80: 411-27. PMID 27030552 DOI: 10.1128/Mmbr.00071-15  0.44
2016 Young HE, Zhao J, Barker JR, Guan Z, Valdivia RH, Zhou P. Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis. Mbio. 7. PMID 27006461 DOI: 10.1128/Mbio.00090-16  1
2016 Maksimchuk KR, Alser KA, Mou R, Valdivia RH, McCafferty DG. The Chlamydia trachomatis Protease CPAF Contains a Cryptic PDZ-Like Domain with Similarity to Human Cell Polarity and Tight Junction PDZ-Containing Proteins. Plos One. 11: e0147233. PMID 26829550 DOI: 10.1371/Journal.Pone.0147233  1
2015 Kokes M, Valdivia RH. Differential Translocation of Host Cellular Materials into the Chlamydia trachomatis Inclusion Lumen during Chemical Fixation. Plos One. 10: e0139153. PMID 26426122 DOI: 10.1371/Journal.Pone.0139153  0.52
2015 Marsh JW, Wee BA, Tyndall JD, Lott WB, Bastidas RJ, Caldwell HD, Valdivia RH, Kari L, Huston WM. A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production. Bmc Microbiology. 15: 194. PMID 26424482 DOI: 10.1186/S12866-015-0533-2  1
2015 Mirrashidi KM, Elwell CA, Verschueren E, Johnson JR, Frando A, Von Dollen J, Rosenberg O, Gulbahce N, Jang G, Johnson T, Jäger S, Gopalakrishnan AM, Sherry J, Dunn JD, Olive A, ... ... Valdivia R, et al. Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. Cell Host & Microbe. PMID 26118995 DOI: 10.1016/J.Chom.2015.06.004  1
2015 Kokes M, Dunn JD, Granek JA, Nguyen BD, Barker JR, Valdivia RH, Bastidas RJ. Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia. Cell Host & Microbe. 17: 716-25. PMID 25920978 DOI: 10.1016/J.Chom.2015.03.014  1
2015 Saka HA, Thompson JW, Chen YS, Dubois LG, Haas JT, Moseley A, Valdivia RH. Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells. Plos One. 10: e0124630. PMID 25909443 DOI: 10.1371/Journal.Pone.0124630  1
2015 Engström P, Krishnan KS, Ngyuen BD, Chorell E, Normark J, Silver J, Bastidas RJ, Welch MD, Hultgren SJ, Wolf-Watz H, Valdivia RH, Almqvist F, Bergström S. A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis. Mbio. 6: e02304-14. PMID 25550323 DOI: 10.1128/Mbio.02304-14  1
2015 Larson CL, Beare PA, Voth DE, Howe D, Cockrell DC, Bastidas RJ, Valdivia RH, Heinzen RA. Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication. Infection and Immunity. 83: 661-70. PMID 25422265 DOI: 10.1128/Iai.02763-14  1
2014 Furuse Y, Finethy R, Saka HA, Xet-Mull AM, Sisk DM, Smith KL, Lee S, Coers J, Valdivia RH, Tobin DM, Cullen BR. Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. Plos One. 9: e106434. PMID 25184567 DOI: 10.1371/Journal.Pone.0106434  1
2014 Nguyen B, Valdivia R. A chemical mutagenesis approach to identify virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis. Methods in Molecular Biology (Clifton, N.J.). 1197: 347-58. PMID 25172291 DOI: 10.1007/978-1-4939-1261-2_20  1
2014 Snavely EA, Kokes M, Dunn JD, Saka HA, Nguyen BD, Bastidas RJ, McCafferty DG, Valdivia RH. Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches. Pathogens and Disease. 71: 336-51. PMID 24838663 DOI: 10.1111/2049-632X.12179  1
2014 Chen YS, Bastidas RJ, Saka HA, Carpenter VK, Richards KL, Plano GV, Valdivia RH. The Chlamydia trachomatis type III secretion chaperone Slc1 engages multiple early effectors, including TepP, a tyrosine-phosphorylated protein required for the recruitment of CrkI-II to nascent inclusions and innate immune signaling. Plos Pathogens. 10: e1003954. PMID 24586162 DOI: 10.1371/Journal.Ppat.1003954  1
2013 Nguyen BD, Valdivia RH. Forward genetic approaches in Chlamydia trachomatis. Journal of Visualized Experiments : Jove. e50636. PMID 24192560 DOI: 10.3791/50636  1
2013 Engström P, Nguyen BD, Normark J, Nilsson I, Bastidas RJ, Gylfe A, Elofsson M, Fields KA, Valdivia RH, Wolf-Watz H, Bergström S. Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity. Journal of Bacteriology. 195: 4221-30. PMID 23852872 DOI: 10.1128/Jb.00506-13  1
2013 Haldar AK, Saka HA, Piro AS, Dunn JD, Henry SC, Taylor GA, Frickel EM, Valdivia RH, Coers J. IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins. Plos Pathogens. 9: e1003414. PMID 23785284 DOI: 10.1371/Journal.Ppat.1003414  1
2013 Bastidas RJ, Elwell CA, Engel JN, Valdivia RH. Chlamydial intracellular survival strategies. Cold Spring Harbor Perspectives in Medicine. 3: a010256. PMID 23637308 DOI: 10.1101/Cshperspect.A010256  1
2013 Barker JR, Koestler BJ, Carpenter VK, Burdette DL, Waters CM, Vance RE, Valdivia RH. STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. Mbio. 4: e00018-13. PMID 23631912 DOI: 10.1128/Mbio.00018-13  1
2012 Thornbrough JM, Hundley T, Valdivia R, Worley MJ. Human genome-wide RNAi screen for host factors that modulate intracellular Salmonella growth. Plos One. 7: e38097. PMID 22701604 DOI: 10.1371/Journal.Pone.0038097  1
2012 Nguyen BD, Valdivia RH. Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches. Proceedings of the National Academy of Sciences of the United States of America. 109: 1263-8. PMID 22232666 DOI: 10.1073/Pnas.1117884109  1
2011 Saka HA, Thompson JW, Chen YS, Kumar Y, Dubois LG, Moseley MA, Valdivia RH. Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms. Molecular Microbiology. 82: 1185-203. PMID 22014092 DOI: 10.1111/J.1365-2958.2011.07877.X  1
2011 Bednar MM, Jorgensen I, Valdivia RH, McCafferty DG. Chlamydia protease-like activity factor (CPAF): characterization of proteolysis activity in vitro and development of a nanomolar affinity CPAF zymogen-derived inhibitor. Biochemistry. 50: 7441-3. PMID 21830778 DOI: 10.1021/Bi201098R  1
2011 Jorgensen I, Bednar MM, Amin V, Davis BK, Ting JP, McCafferty DG, Valdivia RH. The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. Cell Host & Microbe. 10: 21-32. PMID 21767809 DOI: 10.1016/J.Chom.2011.06.008  1
2011 Nguyen BD, Cunningham D, Liang X, Chen X, Toone EJ, Raetz CR, Zhou P, Valdivia RH. Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis. Proceedings of the National Academy of Sciences of the United States of America. 108: 10284-9. PMID 21628561 DOI: 10.1073/Pnas.1107478108  1
2010 Dunn JD, Valdivia RH. Uncivil engineers: Chlamydia, Salmonella and Shigella alter cytoskeleton architecture to invade epithelial cells. Future Microbiology. 5: 1219-32. PMID 20722600 DOI: 10.2217/Fmb.10.77  1
2010 Vignola MJ, Kashatus DF, Taylor GA, Counter CM, Valdivia RH. cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis. The Journal of Biological Chemistry. 285: 21625-35. PMID 20452986 DOI: 10.1074/Jbc.M110.103010  1
2010 Saka HA, Valdivia RH. Acquisition of nutrients by Chlamydiae: unique challenges of living in an intracellular compartment. Current Opinion in Microbiology. 13: 4-10. PMID 20006538 DOI: 10.1016/J.Mib.2009.11.002  0.44
2009 Spaeth KE, Chen YS, Valdivia RH. The Chlamydia type III secretion system C-ring engages a chaperone-effector protein complex. Plos Pathogens. 5: e1000579. PMID 19750218 DOI: 10.1371/Journal.Ppat.1000579  1
2009 Cocchiaro JL, Valdivia RH. New insights into Chlamydia intracellular survival mechanisms. Cellular Microbiology. 11: 1571-8. PMID 19673891 DOI: 10.1111/J.1462-5822.2009.01364.X  1
2008 Cocchiaro JL, Kumar Y, Fischer ER, Hackstadt T, Valdivia RH. Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole. Proceedings of the National Academy of Sciences of the United States of America. 105: 9379-84. PMID 18591669 DOI: 10.1073/Pnas.0712241105  1
2008 Jorgensen I, Valdivia RH. Pmp-like proteins Pls1 and Pls2 are secreted into the lumen of the Chlamydia trachomatis inclusion. Infection and Immunity. 76: 3940-50. PMID 18591235 DOI: 10.1128/Iai.00632-08  1
2006 Valdivia RH, Cormack BP, Falkow S. The uses of green fluorescent protein in prokaryotes. Methods of Biochemical Analysis. 47: 163-78. PMID 16335713 DOI: 10.1002/0471739499.Ch8  1
2003 Shams H, Wizel B, Lakey DL, Samten B, Vankayalapati R, Valdivia RH, Kitchens RL, Griffith DE, Barnes PF. The CD14 receptor does not mediate entry of Mycobacterium tuberculosis into human mononuclear phagocytes. Fems Immunology and Medical Microbiology. 36: 63-9. PMID 12727367 DOI: 10.1016/S0928-8244(03)00039-7  1
2002 Valdivia RH, Baggott D, Chuang JS, Schekman RW. The yeast clathrin adaptor protein complex 1 is required for the efficient retention of a subset of late Golgi membrane proteins. Developmental Cell. 2: 283-94. PMID 11879634 DOI: 10.1016/S1534-5807(02)00127-2  1
2000 Valdivia RH, Cirillo DM, Lee AK, Bouley DM, Falkow S. mig-14 is a horizontally acquired, host-induced gene required for salmonella enterica lethal infection in the murine model of typhoid fever. Infection and Immunity. 68: 7126-31. PMID 11083839 DOI: 10.1128/Iai.68.12.7126-7131.2000  1
2000 Valdivia RH, Ramakrishnan L. Applications of gene fusions to green fluorescent protein and flow cytometry to the study of bacterial gene expression in host cells. Methods in Enzymology. 326: 47-73. PMID 11036634 DOI: 10.1016/S0076-6879(00)26046-1  1
1999 Vazquez-Torres A, Jones-Carson J, Bäumler AJ, Falkow S, Valdivia R, Brown W, Le M, Berggren R, Parks WT, Fang FC. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes. Nature. 401: 804-8. PMID 10548107 DOI: 10.1038/44593  1
1999 Valdivia RH, Matthews RG. Regulatory network analysis (multiple letters) [1] Trends in Microbiology. 7: 398-399. PMID 10498946 DOI: 10.1016/S0966-842X(99)01584-X  1
1998 Valdivia RH, Falkow S. Flow cytometry and bacterial pathogenesis. Current Opinion in Microbiology. 1: 359-63. PMID 10066495 DOI: 10.1016/S1369-5274(98)80042-8  1
1998 Cirillo DM, Valdivia RH, Monack DM, Falkow S. Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. Molecular Microbiology. 30: 175-88. PMID 9786194 DOI: 10.1046/J.1365-2958.1998.01048.X  1
1998 Valdivia RH, Falkow S. 1.1 Detection of Virulence Genes Expressed within Infected Cells Methods in Microbiology. 27: 3-12. DOI: 10.1016/S0580-9517(08)70262-9  1
1997 Valdivia RH, Falkow S. Fluorescence-based isolation of bacterial genes expressed within host cells. Science (New York, N.Y.). 277: 2007-11. PMID 9302299 DOI: 10.1126/Science.277.5334.2007  1
1997 Valdivia RH, Falkow S. Probing bacterial gene expression within host cells. Trends in Microbiology. 5: 360-3. PMID 9294892 DOI: 10.1016/S0966-842X(97)01111-6  1
1997 Ramakrishnan L, Valdivia RH, McKerrow JH, Falkow S. Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens). Infection and Immunity. 65: 767-73. PMID 9009340 DOI: 10.1128/Iai.65.2.767-773.1997  1
1996 Valdivia RH, Falkow S. Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Molecular Microbiology. 22: 367-78. PMID 8930920 DOI: 10.1046/J.1365-2958.1996.00120.X  1
1996 Valdivia RH, Hromockyj AE, Monack D, Ramakrishnan L, Falkow S. Applications for green fluorescent protein (GFP) in the study of host-pathogen interactions. Gene. 173: 47-52. PMID 8707055 DOI: 10.1016/0378-1119(95)00706-7  1
1996 Cormack BP, Valdivia RH, Falkow S. FACS-optimized mutants of the green fluorescent protein (GFP). Gene. 173: 33-8. PMID 8707053 DOI: 10.1016/0378-1119(95)00685-0  1
1991 Valdivia RH, Wang L, Winans SC. Characterization of a putative periplasmic transport system for octopine accumulation encoded by Agrobacterium tumefaciens Ti plasmid pTiA6 Journal of Bacteriology. 173: 6398-6405. PMID 1655707 DOI: 10.1128/Jb.173.20.6398-6405.1991  1
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