| Year |
Citation |
Score |
| 2023 |
Ranoa DRE, Sharma P, Schane CP, Lewis AN, Valdez E, Marada VVVR, Hager MV, Montgomery W, Wolf SP, Schreiber K, Schreiber H, Bailey K, Fan TM, Hergenrother PJ, Roy EJ, ... Kranz DM, et al. Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. Journal For Immunotherapy of Cancer. 11. PMID 37258040 DOI: 10.1136/jitc-2022-006509 |
0.404 |
|
| 2023 |
Schaettler MO, Desai R, Wang AZ, Livingstone AJ, Kobayashi DK, Coxon AT, Bowman-Kirigin JA, Liu CJ, Li M, Bender DE, White MJ, Kranz DM, Johanns TM, Dunn GP. TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma. Journal For Immunotherapy of Cancer. 11. PMID 36808076 DOI: 10.1136/jitc-2022-006121 |
0.35 |
|
| 2020 |
Singh NK, Alonso JA, Harris DT, Anderson SD, Ma J, Hellman LM, Rosenberg AM, Kolawole EM, Evavold BD, Kranz DM, Baker BM. An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes. Biochemistry. PMID 33074657 DOI: 10.1021/acs.biochem.0c00689 |
0.497 |
|
| 2020 |
Chan KK, Dorosky D, Sharma P, Abbasi SA, Dye JM, Kranz DM, Herbert AS, Procko E. Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2. Science (New York, N.Y.). PMID 32753553 DOI: 10.1126/Science.Abc0870 |
0.421 |
|
| 2020 |
Sharma P, Marada VVVR, Cai Q, Kizerwetter M, He Y, Wolf SP, Schreiber K, Clausen H, Schreiber H, Kranz DM. Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides. Proceedings of the National Academy of Sciences of the United States of America. PMID 32541028 DOI: 10.1073/Pnas.1920662117 |
0.526 |
|
| 2020 |
Baker B, Kranz D. Decision letter: Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity Elife. DOI: 10.7554/Elife.58128.Sa1 |
0.305 |
|
| 2020 |
Sharma P, Marada VV, Kizerwetter M, Schane CP, He Y, Wolf SP, Schreiber K, Roy EJ, Clausen H, Schreiber H, Kranz DM. Abstract 3238: Engineering chimeric antigen receptors for adoptive T cell therapy of cancers that express the Tn antigen Immunology. DOI: 10.1158/1538-7445.Am2020-3238 |
0.481 |
|
| 2019 |
Sharma P, Kranz DM. T Cell Receptors for Gene Transfer in Adoptive T Cell Therapy. Critical Reviews in Immunology. 39: 105-122. PMID 31679251 DOI: 10.1615/Critrevimmunol.2019030788 |
0.571 |
|
| 2019 |
He Y, Schreiber K, Wolf SP, Wen F, Steentoft C, Zerweck J, Steiner M, Sharma P, Shepard HM, Posey A, June CH, Mandel U, Clausen H, Leisegang M, Meredith SC, ... Kranz DM, et al. Multiple cancer-specific antigens are targeted by a chimeric antibody receptor on a single cancer cell. Jci Insight. 4. PMID 31672936 DOI: 10.1172/Jci.Insight.130416 |
0.515 |
|
| 2019 |
Sharma P, Harris DT, Stone JD, Kranz DM. T-cell receptors engineered de novo for peptide specificity can mediate optimal T-cell activity without self cross-reactivity. Cancer Immunology Research. PMID 31548259 DOI: 10.1158/2326-6066.Cir-19-0035 |
0.589 |
|
| 2019 |
Parks CA, Henning KR, Pavelko KD, Hansen MJ, Van Keulen VP, Reed BK, Stone JD, Schrum AG, Gil D, Kranz DM, Bordner AJ, Barry MA, Pease LR. Breaking tolerance with engineered class I antigen-presenting molecules. Proceedings of the National Academy of Sciences of the United States of America. PMID 30728302 DOI: 10.1073/Pnas.1807465116 |
0.495 |
|
| 2018 |
Blaha DT, Anderson SD, Yoakum DM, Hager MV, Zha Y, Gajewski TF, Kranz D. High-throughput stability screening of neoantigen/HLA complexes improves immunogenicity predictions. Cancer Immunology Research. PMID 30425106 DOI: 10.1158/2326-6066.Cir-18-0395 |
0.471 |
|
| 2018 |
Sharma P, Harris DT, Hager MV, Kranz DM. Abstract 3581: Convergence of the specificity and cross-reactivity of multiple T cell receptors isolated against a single cancer peptide/HLA complex Immunology. DOI: 10.1158/1538-7445.Am2018-3581 |
0.502 |
|
| 2017 |
Harris DT, Hager MV, Smith SN, Cai Q, Stone JD, Kruger P, Lever M, Dushek O, Schmitt TM, Greenberg PD, Kranz DM. Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains. Journal of Immunology (Baltimore, Md. : 1950). PMID 29288199 DOI: 10.4049/Jimmunol.1700236 |
0.537 |
|
| 2017 |
Sharma P, Kranz DM. Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity. The Journal of Biological Chemistry. PMID 29229779 DOI: 10.1074/Jbc.M117.814152 |
0.48 |
|
| 2017 |
Schmitt TM, Aggen DH, Ishida-Tsubota K, Ochsenreither S, Kranz DM, Greenberg PD. Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro. Nature Biotechnology. PMID 29106410 DOI: 10.1038/Nbt.4004 |
0.807 |
|
| 2016 |
Sharma P, Kranz DM. Recent advances in T-cell engineering for use in immunotherapy. F1000research. 5. PMID 27703664 DOI: 10.12688/F1000Research.9073.1 |
0.593 |
|
| 2016 |
Harris DT, Wang N, Riley TP, Anderson SD, Singh NK, Procko E, Baker BM, Kranz DM. Deep mutational scans as a guide to engineering high-affinity T cell receptor interactions with peptide-bound MHC. The Journal of Biological Chemistry. PMID 27681597 DOI: 10.1074/Jbc.M116.748681 |
0.471 |
|
| 2016 |
Posey AD, Schwab RD, Boesteanu AC, Steentoft C, Mandel U, Engels B, Stone JD, Madsen TD, Schreiber K, Haines KM, Cogdill AP, Chen TJ, Song D, Scholler J, Kranz DM, et al. Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma. Immunity. 44: 1444-1454. PMID 27332733 DOI: 10.1016/J.Immuni.2016.05.014 |
0.501 |
|
| 2016 |
Harris DT, Singh NK, Cai Q, Smith SN, Vander Kooi CW, Procko E, Kranz DM, Baker BM. An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry. Structure (London, England : 1993). PMID 27238970 DOI: 10.1016/J.Str.2016.04.011 |
0.466 |
|
| 2015 |
Harris DT, Kranz DM. Adoptive T Cell Therapies: A Comparison of T Cell Receptors and Chimeric Antigen Receptors. Trends in Pharmacological Sciences. PMID 26705086 DOI: 10.1016/J.Tips.2015.11.004 |
0.548 |
|
| 2015 |
Adams JJ, Narayanan S, Birnbaum ME, Sidhu SS, Blevins SJ, Gee MH, Sibener LV, Baker BM, Kranz DM, Garcia KC. Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nature Immunology. PMID 26523866 DOI: 10.1038/Ni.3310 |
0.465 |
|
| 2015 |
Mattis DM, Chervin AS, Ranoa DR, Kelley SL, Tapping RI, Kranz DM. Studies of the TLR4-associated protein MD-2 using yeast-display and mutational analyses. Molecular Immunology. 68: 203-12. PMID 26320630 DOI: 10.1016/J.Molimm.2015.08.008 |
0.757 |
|
| 2015 |
Sharma P, Wang N, Chervin AS, Quinn CL, Stone JD, Kranz DM. A Multiplex Assay for Detection of Staphylococcal and Streptococcal Exotoxins. Plos One. 10: e0135986. PMID 26305471 DOI: 10.1371/Journal.Pone.0135986 |
0.741 |
|
| 2015 |
Smith SN, Harris DT, Kranz DM. T Cell Receptor Engineering and Analysis Using the Yeast Display Platform. Methods in Molecular Biology (Clifton, N.J.). 1319: 95-141. PMID 26060072 DOI: 10.1007/978-1-4939-2748-7_6 |
0.62 |
|
| 2015 |
Stone JD, Harris DT, Kranz DM. TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity. Current Opinion in Immunology. 33: 16-22. PMID 25618219 DOI: 10.1016/J.Coi.2015.01.003 |
0.582 |
|
| 2014 |
Smith SN, Wang Y, Baylon JL, Singh NK, Baker BM, Tajkhorshid E, Kranz DM. Changing the peptide specificity of a human T-cell receptor by directed evolution. Nature Communications. 5: 5223. PMID 25376839 DOI: 10.1038/Ncomms6223 |
0.568 |
|
| 2014 |
Tosic V, Thomas DL, Kranz DM, Liu J, McFadden G, Shisler JL, MacNeill AL, Roy EJ. Myxoma virus expressing a fusion protein of interleukin-15 (IL15) and IL15 receptor alpha has enhanced antitumor activity. Plos One. 9: e109801. PMID 25329832 DOI: 10.1371/Journal.Pone.0109801 |
0.347 |
|
| 2014 |
Stone JD, Harris DT, Soto CM, Chervin AS, Aggen DH, Roy EJ, Kranz DM. A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control. Cancer Immunology, Immunotherapy : Cii. 63: 1163-76. PMID 25082071 DOI: 10.1007/S00262-014-1586-Z |
0.865 |
|
| 2014 |
Hawse WF, De S, Greenwood AI, Nicholson LK, Zajicek J, Kovrigin EL, Kranz DM, Garcia KC, Baker BM. TCR scanning of peptide/MHC through complementary matching of receptor and ligand molecular flexibility. Journal of Immunology (Baltimore, Md. : 1950). 192: 2885-91. PMID 24523505 DOI: 10.4049/Jimmunol.1302953 |
0.511 |
|
| 2014 |
Sharma P, Wang N, Kranz DM. Soluble T cell receptor Vβ domains engineered for high-affinity binding to staphylococcal or streptococcal superantigens. Toxins. 6: 556-74. PMID 24476714 DOI: 10.3390/Toxins6020556 |
0.578 |
|
| 2013 |
Sharma P, Postel S, Sundberg EJ, Kranz DM. Characterization of the Staphylococcal enterotoxin A: Vβ receptor interaction using human receptor fragments engineered for high affinity. Protein Engineering, Design & Selection : Peds. 26: 781-9. PMID 24167300 DOI: 10.1093/Protein/Gzt054 |
0.459 |
|
| 2013 |
Narayanan S, Kranz DM. The same major histocompatibility complex polymorphism involved in control of HIV influences peptide binding in the mouse H-2Ld system. The Journal of Biological Chemistry. 288: 31784-94. PMID 24064213 DOI: 10.1074/Jbc.M113.478412 |
0.421 |
|
| 2013 |
Stone JD, Kranz DM. Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies. Frontiers in Immunology. 4: 244. PMID 23970885 DOI: 10.3389/Fimmu.2013.00244 |
0.589 |
|
| 2013 |
Smith SN, Sommermeyer D, Piepenbrink KH, Blevins SJ, Bernhard H, Uckert W, Baker BM, Kranz DM. Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes. Journal of Molecular Biology. 425: 4496-507. PMID 23954306 DOI: 10.1016/J.Jmb.2013.08.007 |
0.506 |
|
| 2013 |
Schmitt TM, Aggen DH, Stromnes IM, Dossett ML, Richman SA, Kranz DM, Greenberg PD. Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection. Blood. 122: 348-56. PMID 23673862 DOI: 10.1182/Blood-2013-01-478164 |
0.861 |
|
| 2013 |
Engels B, Engelhard VH, Sidney J, Sette A, Binder DC, Liu RB, Kranz DM, Meredith SC, Rowley DA, Schreiber H. Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity. Cancer Cell. 23: 516-26. PMID 23597565 DOI: 10.1016/J.Ccr.2013.03.018 |
0.558 |
|
| 2013 |
Tallent SM, Degrasse JA, Wang N, Mattis DM, Kranz DM. Novel platform for the detection of Staphylococcus aureus enterotoxin B in foods. Applied and Environmental Microbiology. 79: 1422-7. PMID 23241982 DOI: 10.1128/Aem.02743-12 |
0.34 |
|
| 2013 |
Mattis DM, Spaulding AR, Chuang-Smith ON, Sundberg EJ, Schlievert PM, Kranz DM. Engineering a soluble high-affinity receptor domain that neutralizes staphylococcal enterotoxin C in rabbit models of disease Protein Engineering, Design and Selection. 26: 133-142. PMID 23161916 DOI: 10.1093/Protein/Gzs094 |
0.474 |
|
| 2013 |
Chervin AS, Stone JD, Soto CM, Engels B, Schreiber H, Roy EJ, Kranz DM. Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses. Gene Therapy. 20: 634-44. PMID 23052828 DOI: 10.1038/Gt.2012.80 |
0.846 |
|
| 2013 |
Lynch JN, Donermeyer DL, Weber KS, Kranz DM, Allen PM. Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cells. Molecular Immunology. 53: 283-94. PMID 22982754 DOI: 10.1016/J.Molimm.2012.08.020 |
0.643 |
|
| 2013 |
Soto CM, Stone JD, Chervin AS, Engels B, Schreiber H, Roy EJ, Kranz DM. MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR. Cancer Immunology, Immunotherapy : Cii. 62: 359-69. PMID 22926060 DOI: 10.1007/S00262-012-1336-Z |
0.828 |
|
| 2013 |
Tosic V, Thomas DL, Kranz DM, Liu J, McFadden G, MacNeill AL, Roy EJ. Interleukin-15 (IL-15) and IL-15 receptor alpha fusion protein enhances antitumor activity of myxoma virus Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P137 |
0.324 |
|
| 2013 |
Schmitt TM, Greenberg PD, Aggen DH, Kranz D, Ochsenreither S. Abstract PR12: Early TCRα expression during T cell development for the generation of enhanced-affinity TCRs for TCR gene therapy. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-Pr12 |
0.756 |
|
| 2013 |
Greenberg PD, Ochsenreither S, Schmitt T, Aggen D, Kranz D, Wolfl M, Kuball J, Majeti R, Weissman I, Stromnes I, Schietinger A, Ragnarsson G, Yee C, Bar M, Chapuis A. Abstract IA1: T cells vs. tumor cells: Arming/deploying T cells for a successful battle. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-Ia1 |
0.793 |
|
| 2012 |
Engels B, Chervin AS, Sant AJ, Kranz DM, Schreiber H. Long-term Persistence of CD4(+) but Rapid Disappearance of CD8(+) T Cells Expressing an MHC Class I-restricted TCR of Nanomolar Affinity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 652-660. PMID 28160633 DOI: 10.1038/mt.2011.286 |
0.829 |
|
| 2012 |
Low JL, Naidoo A, Yeo G, Gehring AJ, Ho ZZ, Yau YH, Shochat SG, Kranz DM, Bertoletti A, Grotenbreg GM. Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes. Plos One. 7: e51397. PMID 23251518 DOI: 10.1371/Journal.Pone.0051397 |
0.539 |
|
| 2012 |
Stone JD, Aggen DH, Schietinger A, Schreiber H, Kranz DM. A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs). Oncoimmunology. 1: 863-873. PMID 23162754 DOI: 10.4161/Onci.20592 |
0.809 |
|
| 2012 |
Stone JD, Chervin AS, Schreiber H, Kranz DM. Design and characterization of a protein superagonist of IL-15 fused with IL-15Rα and a high-affinity T cell receptor. Biotechnology Progress. 28: 1588-97. PMID 22961781 DOI: 10.1002/Btpr.1631 |
0.797 |
|
| 2012 |
Lu X, Gibbs JS, Hickman HD, David A, Dolan BP, Jin Y, Kranz DM, Bennink JR, Yewdell JW, Varma R. Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters. Proceedings of the National Academy of Sciences of the United States of America. 109: 15407-12. PMID 22949678 DOI: 10.1073/Pnas.1208696109 |
0.526 |
|
| 2012 |
Kohler PL, Greenwood SD, Nookala S, Kotb M, Kranz DM, Schlievert PM. Staphylococcus aureus isolates encode variant staphylococcal enterotoxin B proteins that are diverse in superantigenicity and lethality. Plos One. 7: e41157. PMID 22815951 DOI: 10.1371/Journal.Pone.0041157 |
0.538 |
|
| 2012 |
Engels B, Chervin AS, Sant AJ, Kranz DM, Schreiber H. Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 652-60. PMID 22233579 DOI: 10.1038/Mt.2011.286 |
0.838 |
|
| 2012 |
Stone JD, Chervin AS, Aggen DH, Kranz DM. T cell receptor engineering. Methods in Enzymology. 503: 189-222. PMID 22230570 DOI: 10.1016/B978-0-12-396962-0.00008-2 |
0.862 |
|
| 2012 |
Aggen DH, Chervin AS, Schmitt TM, Engels B, Stone JD, Richman SA, Piepenbrink KH, Baker BM, Greenberg PD, Schreiber H, Kranz DM. Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains. Gene Therapy. 19: 365-74. PMID 21753797 DOI: 10.1038/Gt.2011.104 |
0.848 |
|
| 2011 |
Stone JD, Artyomov MN, Chervin AS, Chakraborty AK, Eisen HN, Kranz DM. Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRs. Journal of Immunology (Baltimore, Md. : 1950). 187: 6281-90. PMID 22102724 DOI: 10.4049/Jimmunol.1101734 |
0.84 |
|
| 2011 |
Adams JJ, Narayanan S, Liu B, Birnbaum ME, Kruse AC, Bowerman NA, Chen W, Levin AM, Connolly JM, Zhu C, Kranz DM, Garcia KC. T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Immunity. 35: 681-93. PMID 22101157 DOI: 10.1016/J.Immuni.2011.09.013 |
0.819 |
|
| 2011 |
Fuertes MB, Kacha AK, Kline J, Woo SR, Kranz DM, Murphy KM, Gajewski TF. Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells. The Journal of Experimental Medicine. 208: 2005-16. PMID 21930765 DOI: 10.1084/Jem.20101159 |
0.436 |
|
| 2011 |
Bonsor DA, Postel S, Pierce BG, Wang N, Zhu P, Buonpane RA, Weng Z, Kranz DM, Sundberg EJ. Molecular basis of a million-fold affinity maturation process in a protein-protein interaction. Journal of Molecular Biology. 411: 321-8. PMID 21689661 DOI: 10.1016/J.Jmb.2011.06.009 |
0.802 |
|
| 2011 |
Thomas DL, Doty R, Tosic V, Liu J, Kranz DM, McFadden G, Macneill AL, Roy EJ. Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors. Cancer Immunology, Immunotherapy : Cii. 60: 1461-72. PMID 21656158 DOI: 10.1007/S00262-011-1045-Z |
0.438 |
|
| 2011 |
Stone JD, Aggen DH, Chervin AS, Narayanan S, Schmitt TM, Greenberg PD, Kranz DM. Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8. Journal of Immunology (Baltimore, Md. : 1950). 186: 5193-200. PMID 21451107 DOI: 10.4049/Jimmunol.1003755 |
0.843 |
|
| 2011 |
Aggen DH, Chervin AS, Insaidoo FK, Piepenbrink KH, Baker BM, Kranz DM. Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors. Protein Engineering, Design & Selection : Peds. 24: 361-72. PMID 21159619 DOI: 10.1093/Protein/Gzq113 |
0.821 |
|
| 2010 |
Strandberg KL, Rotschafer JH, Vetter SM, Buonpane RA, Kranz DM, Schlievert PM. Staphylococcal superantigens cause lethal pulmonary disease in rabbits. The Journal of Infectious Diseases. 202: 1690-7. PMID 20979456 DOI: 10.1086/657156 |
0.772 |
|
| 2010 |
Wang N, Mattis DM, Sundberg EJ, Schlievert PM, Kranz DM. A single, engineered protein therapeutic agent neutralizes exotoxins from both Staphylococcus aureus and Streptococcus pyogenes. Clinical and Vaccine Immunology : Cvi. 17: 1781-9. PMID 20861327 DOI: 10.1128/Cvi.00277-10 |
0.447 |
|
| 2010 |
Cho S, Swaminathan CP, Bonsor DA, Kerzic MC, Guan R, Yang J, Kieke MC, Andersen PS, Kranz DM, Mariuzza RA, Sundberg EJ. Assessing energetic contributions to binding from a disordered region in a protein-protein interaction . Biochemistry. 49: 9256-68. PMID 20836565 DOI: 10.1021/Bi1008968 |
0.781 |
|
| 2010 |
Persaud SP, Donermeyer DL, Weber KS, Kranz DM, Allen PM. High-affinity T cell receptor differentiates cognate peptide-MHC and altered peptide ligands with distinct kinetics and thermodynamics. Molecular Immunology. 47: 1793-801. PMID 20334923 DOI: 10.1016/J.Molimm.2010.02.013 |
0.653 |
|
| 2010 |
Stone JD, Kranz DM. T cells use rafts for survival. Immunity. 32: 145-7. PMID 20189477 DOI: 10.1016/J.Immuni.2010.02.002 |
0.509 |
|
| 2009 |
Kranz DM. Two mechanisms that account for major histocompatibility complex restriction of T cells. F1000 Biology Reports. 1: 55. PMID 20948629 DOI: 10.3410/B1-55 |
0.556 |
|
| 2009 |
Chervin AS, Stone JD, Bowerman NA, Kranz DM. Cutting edge: inhibitory effects of CD4 and CD8 on T cell activation induced by high-affinity noncognate ligands. Journal of Immunology (Baltimore, Md. : 1950). 183: 7639-43. PMID 19923452 DOI: 10.4049/Jimmunol.0901664 |
0.831 |
|
| 2009 |
John CC, Niermann M, Sharon B, Peterson ML, Kranz DM, Schlievert PM. Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 49: 1893-6. PMID 19911998 DOI: 10.1086/648441 |
0.331 |
|
| 2009 |
Bowerman NA, Colf LA, Garcia KC, Kranz DM. Different strategies adopted by K(b) and L(d) to generate T cell specificity directed against their respective bound peptides. The Journal of Biological Chemistry. 284: 32551-61. PMID 19755422 DOI: 10.1074/Jbc.M109.040501 |
0.84 |
|
| 2009 |
Bowerman NA, Crofts TS, Chlewicki L, Do P, Baker BM, Christopher Garcia K, Kranz DM. Engineering the binding properties of the T cell receptor:peptide:MHC ternary complex that governs T cell activity. Molecular Immunology. 46: 3000-8. PMID 19595460 DOI: 10.1016/J.Molimm.2009.06.012 |
0.852 |
|
| 2009 |
Thomas DL, Kim M, Bowerman NA, Narayanan S, Kranz DM, Schreiber H, Roy EJ. Recurrence of intracranial tumors following adoptive T cell therapy can be prevented by direct and indirect killing aided by high levels of tumor antigen cross-presented on stromal cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 1828-37. PMID 19592642 DOI: 10.4049/Jimmunol.0802322 |
0.814 |
|
| 2009 |
Roy EJ, Sivaguru M, Fried G, Gray BD, Kranz DM. Imaging membrane intercalating near infrared dyes to track multiple cell populations. Journal of Immunological Methods. 348: 18-29. PMID 19559026 DOI: 10.1016/J.Jim.2009.06.006 |
0.334 |
|
| 2009 |
Chervin AS, Stone JD, Holler PD, Bai A, Chen J, Eisen HN, Kranz DM. The impact of TCR-binding properties and antigen presentation format on T cell responsiveness. Journal of Immunology (Baltimore, Md. : 1950). 183: 1166-78. PMID 19553539 DOI: 10.4049/Jimmunol.0900054 |
0.85 |
|
| 2009 |
Richman SA, Kranz DM, Stone JD. Biosensor detection systems: engineering stable, high-affinity bioreceptors by yeast surface display. Methods in Molecular Biology (Clifton, N.J.). 504: 323-50. PMID 19159105 DOI: 10.1007/978-1-60327-569-9_19 |
0.803 |
|
| 2009 |
Stone JD, Chervin AS, Kranz DM. T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity. Immunology. 126: 165-76. PMID 19125887 DOI: 10.1111/J.1365-2567.2008.03015.X |
0.847 |
|
| 2009 |
Richman SA, Aggen DH, Dossett ML, Donermeyer DL, Allen PM, Greenberg PD, Kranz DM. Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments. Molecular Immunology. 46: 902-16. PMID 18962897 DOI: 10.1016/J.Molimm.2008.09.021 |
0.813 |
|
| 2008 |
Jones LL, Colf LA, Bankovich AJ, Stone JD, Gao YG, Chan CM, Huang RH, Garcia KC, Kranz DM. Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors. Biochemistry. 47: 12398-408. PMID 18973345 DOI: 10.1021/Bi801349G |
0.784 |
|
| 2008 |
Jones LL, Colf LA, Stone JD, Garcia KC, Kranz DM. Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation. Journal of Immunology (Baltimore, Md. : 1950). 181: 6255-64. PMID 18941216 DOI: 10.4049/Jimmunol.181.9.6255 |
0.768 |
|
| 2008 |
Chervin AS, Aggen DH, Raseman JM, Kranz DM. Engineering higher affinity T cell receptors using a T cell display system. Journal of Immunological Methods. 339: 175-84. PMID 18854190 DOI: 10.1016/J.Jim.2008.09.016 |
0.869 |
|
| 2008 |
Yang X, Buonpane RA, Moza B, Rahman AK, Wang N, Schlievert PM, McCormick JK, Sundberg EJ, Kranz DM. Neutralization of multiple staphylococcal superantigens by a single-chain protein consisting of affinity-matured, variable domain repeats. The Journal of Infectious Diseases. 198: 344-8. PMID 18522504 DOI: 10.1086/589776 |
0.83 |
|
| 2008 |
Fan TM, Kranz DM, Flavell RA, Roy EJ. Costimulatory strength influences the differential effects of transforming growth factor beta1 for the generation of CD8+ regulatory T cells. Molecular Immunology. 45: 2937-50. PMID 18321576 DOI: 10.1016/J.Molimm.2008.01.019 |
0.42 |
|
| 2008 |
Zhang B, Zhang Y, Bowerman NA, Schietinger A, Fu YX, Kranz DM, Rowley DA, Schreiber H. Equilibrium between host and cancer caused by effector T cells killing tumor stroma. Cancer Research. 68: 1563-71. PMID 18316622 DOI: 10.1158/0008-5472.Can-07-5324 |
0.815 |
|
| 2008 |
Thomas DL, Kranz DM, Roy EJ. Experimental manipulations of afferent immune responses influence efferent immune responses to brain tumors. Cancer Immunology, Immunotherapy : Cii. 57: 1323-33. PMID 18278494 DOI: 10.1007/S00262-008-0467-8 |
0.347 |
|
| 2008 |
Schreiber H, Zhang B, Schietinger A, Rowley D, Bowerman N, Kranz D, Weichselbaum R, Fu Y, Meredith S, Schreiber K. Tumor-promoting stroma impregnated by cancer cells is destroyed by specific T cells European Journal of Cancer Supplements. 6: 66. DOI: 10.1016/S1359-6349(08)71428-9 |
0.799 |
|
| 2007 |
Varani L, Bankovich AJ, Liu CW, Colf LA, Jones LL, Kranz DM, Puglisi JD, Garcia KC. Solution mapping of T cell receptor docking footprints on peptide-MHC. Proceedings of the National Academy of Sciences of the United States of America. 104: 13080-5. PMID 17670943 DOI: 10.1073/Pnas.0703702104 |
0.793 |
|
| 2007 |
Fan TM, Kranz DM, Roy EJ. Enhancing antitumor immunity: combining IL-12 with TGFbeta1 antagonism. Journal of Immunotherapy (Hagerstown, Md. : 1997). 30: 479-89. PMID 17589288 DOI: 10.1097/Cji.0B013E318031A2B2 |
0.35 |
|
| 2007 |
Buonpane RA, Churchill HR, Moza B, Sundberg EJ, Peterson ML, Schlievert PM, Kranz DM. Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists. Nature Medicine. 13: 725-9. PMID 17515896 DOI: 10.1038/Nm1584 |
0.833 |
|
| 2007 |
Truscott SM, Lybarger L, Martinko JM, Mitaksov VE, Kranz DM, Connolly JM, Fremont DH, Hansen TH. Disulfide bond engineering to trap peptides in the MHC class I binding groove. Journal of Immunology (Baltimore, Md. : 1950). 178: 6280-9. PMID 17475856 DOI: 10.4049/Jimmunol.178.10.6280 |
0.544 |
|
| 2007 |
Colf LA, Bankovich AJ, Hanick NA, Bowerman NA, Jones LL, Kranz DM, Garcia KC. How a single T cell receptor recognizes both self and foreign MHC. Cell. 129: 135-46. PMID 17418792 DOI: 10.1016/J.Cell.2007.01.048 |
0.84 |
|
| 2007 |
Richman SA, Kranz DM. Display, engineering, and applications of antigen-specific T cell receptors. Biomolecular Engineering. 24: 361-73. PMID 17409021 DOI: 10.1016/J.Bioeng.2007.02.009 |
0.845 |
|
| 2007 |
Moza B, Varma AK, Buonpane RA, Zhu P, Herfst CA, Nicholson MJ, Wilbuer AK, Seth NP, Wucherpfennig KW, McCormick JK, Kranz DM, Sundberg EJ. Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1. The Embo Journal. 26: 1187-97. PMID 17268555 DOI: 10.1038/Sj.Emboj.7601531 |
0.855 |
|
| 2007 |
Wang L, Zhao Y, Li Z, Guo Y, Jones LL, Kranz DM, Mourad W, Li H. Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC. Nature Structural & Molecular Biology. 14: 169-71. PMID 17220897 DOI: 10.1038/Nsmb1193 |
0.779 |
|
| 2007 |
Zhang B, Bowerman NA, Salama JK, Schmidt H, Spiotto MT, Schietinger A, Yu P, Fu YX, Weichselbaum RR, Rowley DA, Kranz DM, Schreiber H. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. The Journal of Experimental Medicine. 204: 49-55. PMID 17210731 DOI: 10.1084/Jem.20062056 |
0.804 |
|
| 2007 |
Brophy SE, Jones LL, Holler PD, Kranz DM. Cellular uptake followed by class I MHC presentation of some exogenous peptides contributes to T cell stimulatory capacity. Molecular Immunology. 44: 2184-94. PMID 17169430 DOI: 10.1016/J.Molimm.2006.11.016 |
0.839 |
|
| 2006 |
Donermeyer DL, Weber KS, Kranz DM, Allen PM. The study of high-affinity TCRs reveals duality in T cell recognition of antigen: specificity and degeneracy. Journal of Immunology (Baltimore, Md. : 1950). 177: 6911-9. PMID 17082606 DOI: 10.4049/Jimmunol.177.10.6911 |
0.589 |
|
| 2006 |
Jones LL, Brophy SE, Bankovich AJ, Colf LA, Hanick NA, Garcia KC, Kranz DM. Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld. The Journal of Biological Chemistry. 281: 25734-44. PMID 16815841 DOI: 10.1074/Jbc.M604343200 |
0.816 |
|
| 2006 |
Moza B, Buonpane RA, Zhu P, Herfst CA, Rahman AK, McCormick JK, Kranz DM, Sundberg EJ. Long-range cooperative binding effects in a T cell receptor variable domain. Proceedings of the National Academy of Sciences of the United States of America. 103: 9867-72. PMID 16788072 DOI: 10.1073/Pnas.0600220103 |
0.827 |
|
| 2006 |
Richman SA, Healan SJ, Weber KS, Donermeyer DL, Dossett ML, Greenberg PD, Allen PM, Kranz DM. Development of a novel strategy for engineering high-affinity proteins by yeast display. Protein Engineering, Design & Selection : Peds. 19: 255-64. PMID 16549400 DOI: 10.1093/Protein/Gzl008 |
0.849 |
|
| 2006 |
Jiang X, Orr BA, Kranz DM, Shapiro DJ. Estrogen induction of the granzyme B inhibitor, proteinase inhibitor 9, protects cells against apoptosis mediated by cytotoxic T lymphocytes and natural killer cells. Endocrinology. 147: 1419-26. PMID 16306080 DOI: 10.1210/En.2005-0996 |
0.409 |
|
| 2005 |
Weber KS, Donermeyer DL, Allen PM, Kranz DM. Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function. Proceedings of the National Academy of Sciences of the United States of America. 102: 19033-8. PMID 16365315 DOI: 10.1073/Pnas.0507554102 |
0.675 |
|
| 2005 |
Cho S, Swaminathan CP, Yang J, Kerzic MC, Guan R, Kieke MC, Kranz DM, Mariuzza RA, Sundberg EJ. Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure (London, England : 1993). 13: 1775-87. PMID 16338406 DOI: 10.1016/J.Str.2005.08.015 |
0.785 |
|
| 2005 |
Buonpane RA, Moza B, Sundberg EJ, Kranz DM. Characterization of T cell receptors engineered for high affinity against toxic shock syndrome toxin-1. Journal of Molecular Biology. 353: 308-21. PMID 16171815 DOI: 10.1016/J.Jmb.2005.08.041 |
0.852 |
|
| 2005 |
Chlewicki LK, Holler PD, Monti BC, Clutter MR, Kranz DM. High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3. Journal of Molecular Biology. 346: 223-39. PMID 15663940 DOI: 10.1016/J.Jmb.2004.11.057 |
0.845 |
|
| 2005 |
Kranz DM. T cell receptor CDRs: starring versus supporting roles. Nature Immunology. 6: 130-2. PMID 15662440 DOI: 10.1038/Ni0205-130 |
0.573 |
|
| 2004 |
Gawlick U, Kranz DM, Schepkin VD, Roy EJ. A conjugate of a tumor-targeting ligand and a T cell costimulatory antibody to treat brain tumors. Bioconjugate Chemistry. 15: 1137-45. PMID 15366970 DOI: 10.1021/Bc049911E |
0.476 |
|
| 2004 |
Peng KW, Holler PD, Orr BA, Kranz DM, Russell SJ. Targeting virus entry and membrane fusion through specific peptide/MHC complexes using a high-affinity T-cell receptor. Gene Therapy. 11: 1234-9. PMID 15215883 DOI: 10.1038/Sj.Gt.3302286 |
0.83 |
|
| 2004 |
Roy EJ, Gawlick U, Orr BA, Kranz DM. Folate-mediated targeting of T cells to tumors. Advanced Drug Delivery Reviews. 56: 1219-31. PMID 15094217 DOI: 10.1016/J.Addr.2004.01.006 |
0.553 |
|
| 2004 |
Holler PD, Kranz DM. T cell receptors: affinities, cross-reactivities, and a conformer model. Molecular Immunology. 40: 1027-31. PMID 15036906 DOI: 10.1016/J.Molimm.2003.11.013 |
0.836 |
|
| 2004 |
Roth ME, Feng L, McConnell KJ, Schaffer PJ, Guerra CE, Affourtit JP, Piper KR, Guccione L, Hariharan J, Ford MJ, Powell SW, Krishnaswamy H, Lane J, Guccione L, Intrieri G, ... ... Kranz DM, et al. Expression profiling using a hexamer-based universal microarray. Nature Biotechnology. 22: 418-26. PMID 15024387 DOI: 10.1038/Nbt948 |
0.31 |
|
| 2003 |
Dam J, Guan R, Natarajan K, Dimasi N, Chlewicki LK, Kranz DM, Schuck P, Margulies DH, Mariuzza RA. Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b). Nature Immunology. 4: 1213-22. PMID 14595439 DOI: 10.1038/Ni1006 |
0.816 |
|
| 2003 |
Leifert JA, Holler PD, Harkins S, Kranz DM, Whitton JL. The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes. Gene Therapy. 10: 2067-73. PMID 14595379 DOI: 10.1038/Sj.Gt.3302115 |
0.827 |
|
| 2003 |
Yang J, Swaminathan CP, Huang Y, Guan R, Cho S, Kieke MC, Kranz DM, Mariuzza RA, Sundberg EJ. Dissecting cooperative and additive binding energetics in the affinity maturation pathway of a protein-protein interface. The Journal of Biological Chemistry. 278: 50412-21. PMID 14514664 DOI: 10.1074/Jbc.M306848200 |
0.806 |
|
| 2003 |
Chen J, Eisen HN, Kranz DM. A model T-cell receptor system for studying memory T-cell development. Microbes and Infection / Institut Pasteur. 5: 233-40. PMID 12681413 DOI: 10.1016/S1286-4579(03)00016-9 |
0.545 |
|
| 2003 |
Starwalt SE, Masteller EL, Bluestone JA, Kranz DM. Directed evolution of a single-chain class II MHC product by yeast display. Protein Engineering. 16: 147-56. PMID 12676983 DOI: 10.1093/Proeng/Gzg018 |
0.427 |
|
| 2003 |
Holler PD, Kranz DM. Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. Immunity. 18: 255-64. PMID 12594952 DOI: 10.1016/S1074-7613(03)00019-0 |
0.823 |
|
| 2003 |
Lee PU, Kranz DM. Allogeneic and syngeneic class I MHC complexes drive the association of CD8 and TCR on 2C T cells. Molecular Immunology. 39: 687-95. PMID 12531280 DOI: 10.1016/S0161-5890(02)00259-6 |
0.607 |
|
| 2003 |
Brophy SE, Holler PD, Kranz DM. A yeast display system for engineering functional peptide-MHC complexes. Journal of Immunological Methods. 272: 235-46. PMID 12505727 DOI: 10.1016/S0022-1759(02)00439-8 |
0.818 |
|
| 2003 |
Churchill HR, Kranz DM. Analysis of superantigen binding to soluble T-cell receptors. Methods in Molecular Biology (Clifton, N.J.). 214: 101-11. PMID 12489457 DOI: 10.1385/1-59259-367-4:101 |
0.85 |
|
| 2003 |
Churchill HR, Kranz DM. Directed evolution of T-cell receptors for binding superantigens. Methods in Molecular Biology (Clifton, N.J.). 214: 87-99. PMID 12489456 DOI: 10.1385/1-59259-367-4:087 |
0.849 |
|
| 2003 |
Holler PD, Chlewicki LK, Kranz DM. TCRs with high affinity for foreign pMHC show self-reactivity. Nature Immunology. 4: 55-62. PMID 12469116 DOI: 10.1038/Ni863 |
0.861 |
|
| 2001 |
Holler PD, Lim AR, Cho BK, Rund LA, Kranz DM. CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation. The Journal of Experimental Medicine. 194: 1043-52. PMID 11602635 DOI: 10.1084/Jem.194.8.1043 |
0.857 |
|
| 2001 |
Kieke MC, Sundberg E, Shusta EV, Mariuzza RA, Wittrup KD, Kranz DM. High affinity T cell receptors from yeast display libraries block T cell activation by superantigens. Journal of Molecular Biology. 307: 1305-15. PMID 11292343 DOI: 10.1006/Jmbi.2001.4560 |
0.867 |
|
| 2001 |
Griffin MD, Holman PO, Tang Q, Ashourian N, Korthäuer U, Kranz DM, Bluestone JA. Development and applications of surface-linked single chain antibodies against T-cell antigens. Journal of Immunological Methods. 248: 77-90. PMID 11223070 DOI: 10.1016/S0022-1759(00)00344-6 |
0.551 |
|
| 2001 |
Cho BK, Lian KC, Lee P, Brunmark A, McKinley C, Chen J, Kranz DM, Eisen HN. Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor. Proceedings of the National Academy of Sciences of the United States of America. 98: 1723-7. PMID 11172018 DOI: 10.1073/Pnas.98.4.1723 |
0.604 |
|
| 2001 |
Kranz DM. Incompatible differences: view of an allogeneic pMHC-TCR complex. Nature Immunology. 1: 277-8. PMID 11017095 DOI: 10.1038/79716 |
0.549 |
|
| 2000 |
Roy EJ, Gawlick U, Orr BA, Rund LA, Webb AG, Kranz DM. IL-12 treatment of endogenously arising murine brain tumors. Journal of Immunology (Baltimore, Md. : 1950). 165: 7293-9. PMID 11120864 DOI: 10.4049/Jimmunol.165.12.7293 |
0.356 |
|
| 2000 |
Shusta EV, Holler PD, Kieke MC, Kranz DM, Wittrup KD. Directed evolution of a stable scaffold for T-cell receptor engineering. Nature Biotechnology. 18: 754-9. PMID 10888844 DOI: 10.1038/77325 |
0.849 |
|
| 2000 |
Griffin MD, Hong DK, Holman PO, Lee KM, Whitters MJ, O'Herrin SM, Fallarino F, Collins M, Segal DM, Gajewski TF, Kranz DM, Bluestone JA. Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152). Journal of Immunology (Baltimore, Md. : 1950). 164: 4433-42. PMID 10779742 DOI: 10.4049/Jimmunol.164.9.4433 |
0.544 |
|
| 2000 |
Holler PD, Holman PO, Shusta EV, O'Herrin S, Wittrup KD, Kranz DM. In vitro evolution of a T cell receptor with high affinity for peptide/MHC. Proceedings of the National Academy of Sciences of the United States of America. 97: 5387-92. PMID 10779548 DOI: 10.1073/Pnas.080078297 |
0.837 |
|
| 2000 |
Lee PU, Churchill HR, Daniels M, Jameson SC, Kranz DM. Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexes. The Journal of Experimental Medicine. 191: 1355-64. PMID 10770802 DOI: 10.1084/Jem.191.8.1355 |
0.849 |
|
| 2000 |
Churchill HR, Andersen PS, Parke EA, Mariuzza RA, Kranz DM. Mapping the energy of superantigen Staphylococcus enterotoxin C3 recognition of an alpha/beta T cell receptor using alanine scanning mutagenesis. The Journal of Experimental Medicine. 191: 835-46. PMID 10704464 DOI: 10.1084/Jem.191.5.835 |
0.845 |
|
| 1999 |
Shusta EV, Kieke MC, Parke E, Kranz DM, Wittrup KD. Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency. Journal of Molecular Biology. 292: 949-56. PMID 10512694 DOI: 10.1006/Jmbi.1999.3130 |
0.789 |
|
| 1999 |
Manning TC, Kranz DM. Binding energetics of T-cell receptors: correlation with immunological consequences. Immunology Today. 20: 417-22. PMID 10462742 DOI: 10.1016/S0167-5699(99)01508-X |
0.549 |
|
| 1999 |
Rund LA, Cho BK, Manning TC, Holler PD, Roy EJ, Kranz DM. Bispecific agents target endogenous murine T cells against human tumor xenografts. International Journal of Cancer. Journal International Du Cancer. 83: 141-9. PMID 10449621 DOI: 10.1002/(Sici)1097-0215(19990924)83:1<141::Aid-Ijc24>3.0.Co;2-0 |
0.809 |
|
| 1999 |
Pledger DW, Brodnicki TC, Graham BL, Tetin S, Kranz DM, Linthicum DS. Construction and characterization of two anti-sweetener single chain antibodies using radioligand binding, fluorescence and circular dichroism spectroscopy Journal of Molecular Recognition. 12: 258-266. PMID 10440997 DOI: 10.1002/(Sici)1099-1352(199907/08)12:4<258::Aid-Jmr464>3.0.Co;2-A |
0.407 |
|
| 1999 |
Kieke MC, Shusta EV, Boder ET, Teyton L, Wittrup KD, Kranz DM. Selection of functional T cell receptor mutants from a yeast surface-display library. Proceedings of the National Academy of Sciences of the United States of America. 96: 5651-6. PMID 10318939 DOI: 10.1073/Pnas.96.10.5651 |
0.859 |
|
| 1999 |
Andersen PS, Lavoie PM, Sékaly RP, Churchill H, Kranz DM, Schlievert PM, Karjalainen K, Mariuzza RA. Role of the T cell receptor α chain in stabilizing TCR-superantigen- MHC class II complexes Immunity. 10: 473-483. PMID 10229190 DOI: 10.1016/S1074-7613(00)80047-3 |
0.836 |
|
| 1999 |
Manning TC, Parke EA, Teyton L, Kranz DM. Effects of complementarity determining region mutations on the affinity of an α/β t cell receptor: Measuring the energy associated with CD4/CD8 repertoire skewing Journal of Experimental Medicine. 189: 461-470. PMID 9927508 DOI: 10.1084/Jem.189.3.461 |
0.468 |
|
| 1999 |
Kulkami S, Holman P, Kranz D, van Seventer GA, van Seventer J, Kopelan A, Woodle ES. CELL-MEDIATED DELIVERY OF PROGRAMMED CELL DEATH SIGNALS FOLLOWING GENE TRANSFER OF A MEMBRANE-ANCHORED SINGLE-CHAIN ANTIBODY SPECIFIC FOR CLASS I MHC Transplantation. 67: S212. DOI: 10.1097/00007890-199904150-00845 |
0.369 |
|
| 1998 |
Cho BK, Kieke MC, Boder ET, Wittrup KD, Kranz DM. A yeast surface display system for the discovery of ligands that trigger cell activation. Journal of Immunological Methods. 220: 179-88. PMID 9839939 DOI: 10.1016/S0022-1759(98)00158-6 |
0.852 |
|
| 1998 |
Patrick TA, Kranz DM, Zachary JF, Roy EJ. Intracerebral bispecific ligand-antibody conjugate increases survival of animals bearing endogenously arising brain tumors. International Journal of Cancer. Journal International Du Cancer. 78: 470-9. PMID 9797136 DOI: 10.1002/(Sici)1097-0215(19981109)78:4<470::Aid-Ijc13>3.0.Co;2-A |
0.453 |
|
| 1998 |
Kranz DM, Manning TC, Rund LA, Cho BK, Gruber MM, Roy EJ. Targeting tumor cells with bispecific antibodies and T cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 53: 77-84. PMID 9741915 DOI: 10.1016/S0168-3659(97)00239-3 |
0.527 |
|
| 1998 |
Kulkarni S, Holman P, Kranz D, Zhou N, Van Seventer J, Woodle ES. Construction of a single-chain antibody derived from 5H7, a monoclonal antibody specific for a death signaling domain of human class I major histocompatibility complex. Transplantation Proceedings. 30: 1081. PMID 9636438 DOI: 10.1016/S0041-1345(98)00160-2 |
0.331 |
|
| 1998 |
Roy EJ, Cho BK, Rund LA, Patrick TA, Kranz DM. Targeting T cells against brain tumors with a bispecific ligand-antibody conjugate. International Journal of Cancer. Journal International Du Cancer. 76: 761-6. PMID 9610737 DOI: 10.1002/(Sici)1097-0215(19980529)76:5<761::Aid-Ijc23>3.0.Co;2-5 |
0.487 |
|
| 1998 |
Manning TC, Schlueter CJ, Brodnicki TC, Parke EA, Speir JA, Garcia KC, Teyton L, Wilson IA, Kranz DM. Alanine scanning mutagenesis of an αβ T cell receptor: Mapping the energy of antigen recognition Immunity. 8: 413-425. PMID 9586632 DOI: 10.1016/S1074-7613(00)80547-6 |
0.552 |
|
| 1998 |
Kulkarni S, Van Seventer J, Zhou N, Holman P, Kranz D, Woodle ES. EXPRESSION OF A GPI-ANCHORED, SINGLE-CHAIN ANTIBODY SPECIFIC FOR A CELL DEATH SIGNALING DOMAIN OF HUMAN CLASS I MHC Transplantation. 65: 122. DOI: 10.1097/00007890-199805131-00173 |
0.38 |
|
| 1997 |
Kieke MC, Cho BK, Boder ET, Kranz DM, Wittrup KD. Isolation of anti-T cell receptor scFv mutants by yeast surface display. Protein Engineering. 10: 1303-10. PMID 9514119 DOI: 10.1093/Protein/10.11.1303 |
0.831 |
|
| 1997 |
Cho BK, Roy EJ, Patrick TA, Kranz DM. Single-chain Fv/folate conjugates mediate efficient lysis of folate-receptor-positive tumor cells. Bioconjugate Chemistry. 8: 338-46. PMID 9177839 DOI: 10.1021/Bc9700244 |
0.458 |
|
| 1997 |
Patrick TA, Kranz DM, van Dyke TA, Roy EJ. Folate receptors as potential therapeutic targets in choroid plexus tumors of SV40 transgenic mice. Journal of Neuro-Oncology. 32: 111-23. PMID 9120540 DOI: 10.1023/A:1005713115147 |
0.368 |
|
| 1996 |
Schodin BA, Schlueter CJ, Kranz DM. Binding properties and solubility of single-chain T cell receptors expressed in E. coli. Molecular Immunology. 33: 819-29. PMID 8811077 DOI: 10.1016/0161-5890(96)00038-7 |
0.467 |
|
| 1996 |
Schodin BA, Tsomides TJ, Kranz DM. Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity. Immunity. 5: 137-46. PMID 8769477 DOI: 10.1016/S1074-7613(00)80490-2 |
0.548 |
|
| 1996 |
Manning TC, Schodin BA, Kranz DM. A strategy for the synthesis and screening of thiol-modified peptide variants recognized by T cells. Journal of Immunological Methods. 192: 125-32. PMID 8699007 DOI: 10.1016/0022-1759(96)00048-8 |
0.407 |
|
| 1996 |
Brodnicki TC, Holman PO, Kranz DM. Reactivity and epitope mapping of single-chain T cell receptors with monoclonal antibodies. Molecular Immunology. 33: 253-63. PMID 8649446 DOI: 10.1016/0161-5890(95)00142-5 |
0.454 |
|
| 1996 |
Schlueter CJ, Schodin BA, Tetin SY, Kranz DM. Specificity and binding properties of a single-chain T cell receptor. Journal of Molecular Biology. 256: 859-69. PMID 8601837 DOI: 10.1006/Jmbi.1996.0132 |
0.562 |
|
| 1996 |
Brodnicki TC, Holman PO, Kranz DM. Erratum: Reactivity and epitope mapping of single chain T cell receptors with monoclonal antibodies (Molecular Immunology (1996) 33 (253- 263)) Molecular Immunology. 33. DOI: 10.1016/0161-5890(96)82925-7 |
0.467 |
|
| 1995 |
Kranz DM, Gruber M, Wilson ER. Properties of bispecific single chain antibodies expressed in Escherichia coli Journal of Hematotherapy. 4: 403-408. PMID 8581376 DOI: 10.1089/Scd.1.1995.4.403 |
0.517 |
|
| 1995 |
Cho BK, Schodin BA, Kranz DM. Characterization of a single-chain antibody to the beta-chain of the T cell receptor. The Journal of Biological Chemistry. 270: 25819-26. PMID 7592766 DOI: 10.1074/Jbc.270.43.25819 |
0.508 |
|
| 1995 |
Kranz DM, Patrick TA, Brigle KE, Spinella MJ, Roy EJ. Conjugates of folate and anti-T-cell-receptor antibodies specifically target folate-receptor-positive tumor cells for lysis. Proceedings of the National Academy of Sciences of the United States of America. 92: 9057-61. PMID 7568072 DOI: 10.1073/Pnas.92.20.9057 |
0.485 |
|
| 1994 |
Tjoa BA, Kranz DM. Sequence restrictions in T cell receptor beta-chains that have specificity for a self-peptide/Ld complex. Molecular Immunology. 31: 705-11. PMID 7518567 DOI: 10.1016/0161-5890(94)90144-9 |
0.346 |
|
| 1992 |
Hoo WF, Lacy MJ, Denzin LK, Voss EW, Hardman KD, Kranz DM. Characterization of a single-chain T-cell receptor expressed in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 89: 4759-63. PMID 1584815 DOI: 10.1073/Pnas.89.10.4759 |
0.691 |
|
| 1992 |
Johnson NA, Keeney JB, Hedayat M, Clary KW, Kranz DM, Hansen TH. T cell receptor rearrangements in various S49 lymphoma sublines. Molecular Immunology. 29: 1325-35. PMID 1328877 DOI: 10.1016/0161-5890(92)90169-X |
0.371 |
|
| 1992 |
Holman PO, Lacy MJ, Roth ME, Kranz DM. Mechanisms that generate junctional diversity in alpha and delta chains that use the Tcrd-V3 gene product. Immunogenetics. 35: 33-40. PMID 1309508 DOI: 10.1007/Bf00216624 |
0.336 |
|
| 1989 |
Lacy MJ, McNeil LK, Roth ME, Kranz DM. T-cell receptor δ-chain diversity in peripheral lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 86: 1023-1026. PMID 2783779 DOI: 10.1073/Pnas.86.3.1023 |
0.476 |
|
| 1989 |
Loh DY, Sha WC, Nelson CA, Newberry RD, Kranz DM, Russell JH. Positive and negative selection of T lymphocytes Cold Spring Harbor Symposia On Quantitative Biology. 54: 147-151. PMID 2639750 DOI: 10.1101/Sqb.1989.054.01.018 |
0.395 |
|
| 1989 |
Roth ME, Lacy MJ, McNeil LK, Kranz DM. Correction: selection of variable-joining region combinations in the T cell receptor Science. 245: 1032. PMID 2528208 DOI: 10.1126/Science.2528208 |
0.475 |
|
| 1988 |
Sha WC, Nelson CA, Newberry RD, Kranz DM, Russell JH, Loh DY. Positive and negative selection of an antigen receptor on T cells in transgenic mice Nature. 336: 73-76. PMID 3263574 DOI: 10.1038/336073A0 |
0.565 |
|
| 1988 |
Gibson AL, Herron JN, He XM, Patrick VA, Mason ML, Lin JN, Kranz DM, Voss EW, Edmundson AB. Differences in crystal properties and ligand affinities of an antifluorescyl Fab (4-4-20) in two solvent systems. Proteins. 3: 155-60. PMID 3255103 DOI: 10.1002/Prot.340030304 |
0.589 |
|
| 1988 |
Roth ME, Lacy MJ, Mcneil LK, Kranz DM. Selection of variable-joining region combinations in the α chain of the T cell receptor Science. 241: 1354-1358. PMID 2970673 DOI: 10.1126/Science.2970673 |
0.477 |
|
| 1987 |
Eisen HN, Verret CR, Firmenich AA, Kranz DM. Resistance of cytolytic T lymphocytes to the lytic components they release. Annales De L'Institut Pasteur. Immunology. 138: 328-31. PMID 3496910 DOI: 10.1016/S0769-2625(87)80089-2 |
0.357 |
|
| 1987 |
Kranz DM, Eisen HN. Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 84: 3375-9. PMID 2953028 DOI: 10.1073/Pnas.84.10.3375 |
0.492 |
|
| 1987 |
Verret CR, Firmenich AA, Kranz DM, Eisen HN. Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules. The Journal of Experimental Medicine. 166: 1536-47. PMID 2445890 DOI: 10.1084/Jem.166.5.1536 |
0.454 |
|
| 1986 |
Herron JN, Kranz DM, Jameson DM, Voss EW. Thermodynamic properties of ligand binding by monoclonal anti-fluorescyl antibodies. Biochemistry. 25: 4602-9. PMID 3768301 DOI: 10.1021/Bi00364A022 |
0.591 |
|
| 1986 |
Reilly EB, Kranz DM, Tonegawa S, Eisen HN. A functional gamma gene formed from known gamma-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes. Nature. 321: 878-80. PMID 3487735 DOI: 10.1038/321878A0 |
0.477 |
|
| 1986 |
Novotný J, Tonegawa S, Saito H, Kranz DM, Eisen HN. Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains. Proceedings of the National Academy of Sciences of the United States of America. 83: 742-6. PMID 3484824 DOI: 10.1073/Pnas.83.3.742 |
0.564 |
|
| 1986 |
Hubbard SC, Kranz DM, Longmore GD, Sitkovsky MV, Eisen HN. Glycosylation of the T-cell antigen-specific receptor and its potential role in lectin-mediated cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 83: 1852-6. PMID 3081904 DOI: 10.1073/Pnas.83.6.1852 |
0.561 |
|
| 1986 |
Lieberman J, Verret CR, Kranz DM, Hubbard SC, Saito H, Raulet DH, Tonegawa S, Eisen HN. A phosphorylated, disulfide-linked membrane protein in murine cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 83: 7870-4. PMID 2945206 DOI: 10.1073/Pnas.83.20.7870 |
0.46 |
|
| 1985 |
Liu MA, Kranz DM, Kurnick JT, Boyle LA, Levy R, Eisen HN. Heteroantibody duplexes target cells for lysis by cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 82: 8648-52. PMID 3936039 DOI: 10.1073/Pnas.82.24.8648 |
0.532 |
|
| 1985 |
Kranz DM, Saito H, Disteche CM, Swisshelm K, Pravtcheva D, Ruddle FH, Eisen HN, Tonegawa S. Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene. Science (New York, N.Y.). 227: 941-5. PMID 3918347 DOI: 10.1126/Science.3918347 |
0.426 |
|
| 1985 |
Hayday AC, Saito H, Gillies SD, Kranz DM, Tanigawa G, Eisen HN, Tonegawa S. Structure, organization, and somatic rearrangement of T cell gamma genes. Cell. 40: 259-69. PMID 3917858 DOI: 10.1016/0092-8674(85)90140-0 |
0.403 |
|
| 1985 |
Eisen HN, Liu MA, Kranz DM. The central role of the antigen-specific receptor complex in triggering cytolytic activity of cytotoxic T lymphocytes. Bioscience Reports. 5: 885-92. PMID 3879457 DOI: 10.1007/Bf01119900 |
0.506 |
|
| 1985 |
Kranz DM, Saito H, Heller M, Takagaki Y, Haas W, Eisen HN, Tonegawa S. Limited diversity of the rearranged T-cell gamma gene. Nature. 313: 752-5. PMID 3871915 DOI: 10.1038/313752A0 |
0.455 |
|
| 1985 |
Heilig JS, Glimcher LH, Kranz DM, Clayton LK, Greenstein JL, Saito H, Maxam AM, Burakoff SJ, Eisen HN, Tonegawa S. Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants. Nature. 317: 68-70. PMID 2412133 DOI: 10.1038/317068A0 |
0.463 |
|
| 1984 |
Kranz DM, Sherman DH, Sitkovsky MV, Pasternack MS, Eisen HN. Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera. Proceedings of the National Academy of Sciences of the United States of America. 81: 573-7. PMID 6607474 DOI: 10.1073/Pnas.81.2.573 |
0.497 |
|
| 1984 |
Kranz DM, Tonegawa S, Eisen HN. Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 81: 7922-6. PMID 6334855 DOI: 10.1073/Pnas.81.24.7922 |
0.538 |
|
| 1984 |
Sherman DH, Kranz DM, Eisen HN. Expression of structurally diverse Qa-2-encoded molecules on the surface of cloned cytotoxic T lymphocytes. The Journal of Experimental Medicine. 160: 1421-30. PMID 6333483 DOI: 10.1084/Jem.160.5.1421 |
0.397 |
|
| 1984 |
Saito H, Kranz DM, Takagaki Y, Hayday AC, Eisen HN, Tonegawa S. Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. Nature. 309: 757-62. PMID 6330561 DOI: 10.1038/309757A0 |
0.493 |
|
| 1984 |
Saito H, Kranz DM, Takagaki Y, Hayday AC, Eisen HN, Tonegawa S. A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature. 312: 36-40. PMID 6208487 DOI: 10.1038/312036A0 |
0.427 |
|
| 1983 |
Ballard DW, Kranz DM, Voss EW. Monoclonal IgM antibody exhibiting high-affinity binding and cryoglobulin properties. Proceedings of the National Academy of Sciences of the United States of America. 80: 5071-4. PMID 6348779 DOI: 10.1073/Pnas.80.16.5071 |
0.601 |
|
| 1983 |
Kranz DM, Ballard DW, Voss EW. Expression of defined idiotypes throughout the BALB/c anti-fluorescyl antibody response: affinity and idiotype analyses of heterogeneous antibodies. Molecular Immunology. 20: 1313-22. PMID 6197635 DOI: 10.1016/0161-5890(83)90162-1 |
0.594 |
|
| 1983 |
Kranz DM, Voss EW. Idiotypic analysis of monoclonal anti-fluorescyl antibodies: localization and characterization of idiotypic determinants. Molecular Immunology. 20: 1301-12. PMID 6197634 DOI: 10.1016/0161-5890(83)90161-X |
0.617 |
|
| 1982 |
Kranz DM, Herron JN, Voss EW. Mechanisms of ligand binding by monoclonal anti-fluorescyl antibodies. The Journal of Biological Chemistry. 257: 6987-95. PMID 6806261 |
0.567 |
|
| 1982 |
Jarvis MR, Casperson GF, Kranz DM, Voss EW. Affinity maturation of NZB and BALB/cV mice anti-fluorescyl response. Molecular Immunology. 19: 525-33. PMID 6211610 DOI: 10.1016/0161-5890(82)90220-6 |
0.561 |
|
| 1981 |
Kranz DM, Voss EW. Partial elucidation of an anti-hapten repertoire in BALB/c mice: comparative characterization of several monoclonal anti-fluorescyl antibodies. Molecular Immunology. 18: 889-98. PMID 7335083 DOI: 10.1016/0161-5890(81)90012-2 |
0.581 |
|
| 1981 |
Kranz DM, Herron JN, Giannis DE, Voss EW. Kinetics and mechanism of deuterium oxide-induced fluorescence enhancement of fluorescyl ligand bound to specific heterogeneous and homogeneous antibodies. The Journal of Biological Chemistry. 256: 4433-8. PMID 7217089 |
0.525 |
|
| 1981 |
Kranz DM, Voss EW. Restricted reassociation of heavy and light chains from hapten-specific monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 78: 5807-11. PMID 6795637 DOI: 10.1073/Pnas.78.9.5807 |
0.575 |
|
| 1980 |
Kranz DM, Billing PA, Herron JN, Voss EW. Modified hybridoma methodology: antigen-directed chemically mediated cell fusion. Immunological Communications. 9: 639-51. PMID 7439926 DOI: 10.3109/08820138009066015 |
0.646 |
|
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