Linda S. Birnbaum - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Toxicology, Biochemistry

203 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 VanEtten SL, Bonner MR, Ren X, Birnbaum LS, Kostyniak PJ, Wang J, Olson JR. Telomeres as targets for the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) in rats. Toxicology and Applied Pharmacology. 115264. PMID 33022284 DOI: 10.1016/j.taap.2020.115264  0.301
2019 Blum A, Behl M, Birnbaum L, Diamond ML, Phillips A, Singla V, Sipes NS, Stapleton HM, Venier M. Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers? Environmental Science & Technology Letters. 6: 638-649. PMID 32494578 DOI: 10.1021/Acs.Estlett.9B00582  0.388
2019 Rock KD, Gillera SEA, Devarasetty P, Horman B, Knudsen G, Birnbaum LS, Fenton SE, Patisaul HB. Sex-Specific Behavioral Effects Following Developmental Exposure to Tetrabromobisphenol A (TBBPA) in Wistar Rats. Neurotoxicology. PMID 31541695 DOI: 10.1016/J.Neuro.2019.09.003  0.392
2019 Trexler AW, Knudsen GA, Nicklisch SCT, Birnbaum LS, Cannon RE. 2,4,6-Tribromophenol Exposure Decreases P-glycoprotein Transport at the Blood-Brain Barrier. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31368499 DOI: 10.1093/Toxsci/Kfz155  0.306
2019 Cannon RE, Trexler AW, Knudsen GA, Evans RA, Birnbaum LS. Tetrabromobisphenol A (TBBPA) Alters ABC Transport at the Blood-Brain Barrier. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30830211 DOI: 10.1093/Toxsci/Kfz059  0.301
2019 Knudsen GA, Trexler AW, Richards AC, Hall SM, Hughes MF, Birnbaum LS. 2,4,6-Tribromophenol disposition and kinetics in rodents: effects of dose, route, sex, and species. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30768125 DOI: 10.1093/Toxsci/Kfz044  0.398
2018 Knudsen GA, Hughes MF, Birnbaum LS. Dermal disposition of Tetrabromobisphenol A Bis(2,3-dibromopropyl) ether (TBBPA-BDBPE) using rat and human skin. Toxicology Letters. PMID 30481582 DOI: 10.1016/J.Toxlet.2018.11.011  0.327
2018 Emond C, DeVito MJ, Diliberto JJ, Birnbaum LS. The Influence of Obesity on the Pharmacokinetics of Dioxin in Mice: An Assessment Using Classical and PBPK Modeling. Toxicological Sciences : An Official Journal of the Society of Toxicology. 164: 218-228. PMID 29596651 DOI: 10.1093/Toxsci/Kfy078  0.335
2018 Petriello MC, Charnigo R, Sunkara M, Soman S, Pavuk M, Birnbaum L, Morris AJ, Hennig B. Relationship between serum trimethylamine N-oxide and exposure to dioxin-like pollutants. Environmental Research. 162: 211-218. PMID 29353125 DOI: 10.1016/J.Envres.2018.01.007  0.396
2017 Gross L, Birnbaum LS. Regulating toxic chemicals for public and environmental health. Plos Biology. 15: e2004814. PMID 29252982 DOI: 10.1371/Journal.Pbio.2004814  0.313
2017 Knudsen GA, Hall SM, Richards AC, Birnbaum LS. TBBPA disposition and kinetics in pregnant and nursing Wistar Han IGS rats. Chemosphere. 192: 5-13. PMID 29091796 DOI: 10.1016/J.Chemosphere.2017.10.122  0.344
2016 Szabo DT, Pathmasiri W, Sumner S, Birnbaum LS. Serum Metabolomic Profiles in Neonatal Mice following Oral Brominated Flame Retardant Exposures to Hexabromocyclododecane (HBCD) Alpha, Gamma, and Commercial Mixture. Environmental Health Perspectives. PMID 27814246 DOI: 10.1289/EHP242  0.687
2016 Knudsen GA, Sanders JM, Hughes MF, Hull EP, Birnbaum LS. The Biological Fate of Decabromodiphenyl ethane following Oral, Dermal, or Intravenous administration. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-35. PMID 27771980 DOI: 10.1080/00498254.2016.1250180  0.378
2016 Knudsen GA, Sanders JM, Birnbaum LS. Disposition of the emerging brominated flame retardant, 2-Ethylhexyl 2,3,4,5-Tetrabromobenzoate, in female SD rats and male B6C3F1 mice: effects of dose, route, and repeated administration. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27613714 DOI: 10.1093/Toxsci/Kfw176  0.39
2016 Cui Y, Balshaw DM, Kwok RK, Thompson CL, Collman GW, Birnbaum LS. The Exposome: Embracing the Complexity for Discovery in Environmental Health. Environmental Health Perspectives. 124: A137-A140. PMID 27479988 DOI: 10.1289/Ehp412  0.34
2016 Knudsen GA, Sanders JM, Birnbaum LS. Disposition of the emerging brominated flame retardant, bis(2-ethylhexyl) tetrabromophthalate, in female Sprague Dawley rats: effects of dose, route and repeated administration. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-10. PMID 27098498 DOI: 10.1080/00498254.2016.1174793  0.397
2016 Emond C, DeVito M, Warner M, Eskenazi B, Mocarelli P, Birnbaum LS. An assessment of dioxin exposure across gestation and lactation using a PBPK model and new data from Seveso Environment International. 92: 23-32. DOI: 10.1016/J.Envint.2016.03.015  0.308
2015 Szabo ST, Harry GJ, Hayden KM, Szabo DT, Birnbaum L. Comparison of metal levels between post-mortem brain and ventricular fluid in Alzheimer's Disease and non-demented elderly controls. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26721301 DOI: 10.1093/Toxsci/Kfv325  0.672
2015 Carlin DJ, Naujokas MF, Bradham KD, Cowden J, Heacock M, Henry HF, Lee JS, Thomas DJ, Thompson C, Tokar EJ, Waalkes MP, Birnbaum LS, Suk WA. Arsenic and Environmental Health: State of the Science and Future Research Opportunities. Environmental Health Perspectives. PMID 26587579 DOI: 10.1289/Ehp.1510209  0.357
2015 Knudsen GA, Hughes MF, McIntosh KL, Sanders JM, Birnbaum LS. Estimation of tetrabromobisphenol A (TBBPA) percutaneous uptake in humans using the parallelogram method. Toxicology and Applied Pharmacology. PMID 26387765 DOI: 10.1016/J.Taap.2015.09.012  0.346
2015 Dinse GE, Jusko TA, Whitt IZ, Co CA, Parks CG, Satoh M, Chan EK, Rose KM, Walker NJ, Birnbaum LS, Zeldin DC, Weinberg CR, Miller FW. Associations between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004. Environmental Health Perspectives. PMID 26252071 DOI: 10.1289/Ehp.1409345  0.326
2015 Grossman E, Vandenberg LN, Thayer K, Birnbaum LS. Theodora (Theo) Colborn: 1927-2014. Environmental Health Perspectives. 123: A54. PMID 25730706 DOI: 10.1289/Ehp.1509743  0.307
2015 Hoffman K, Garantziotis S, Birnbaum LS, Stapleton HM. Monitoring indoor exposure to organophosphate flame retardants: hand wipes and house dust. Environmental Health Perspectives. 123: 160-5. PMID 25343780 DOI: 10.1289/Ehp.1408669  0.347
2014 Knudsen GA, Sanders JM, Sadik AM, Birnbaum LS. TITLE Disposition and kinetics of Tetrabromobisphenol A in female Wistar Han rats. Toxicology Reports. 1: 214-223. PMID 24977115 DOI: 10.1016/J.Toxrep.2014.03.005  0.368
2014 Hoffman K, Fang M, Horman B, Patisaul HB, Garantziotis S, Birnbaum LS, Stapleton HM. Urinary tetrabromobenzoic acid (TBBA) as a biomarker of exposure to the flame retardant mixture Firemaster® 550. Environmental Health Perspectives. 122: 963-9. PMID 24823833 DOI: 10.1289/Ehp.1308028  0.318
2013 Emond C, Sanders JM, Wikoff D, Birnbaum LS. Proposed mechanistic description of dose-dependent BDE-47 urinary elimination in mice using a physiologically based pharmacokinetic model. Toxicology and Applied Pharmacology. 273: 335-44. PMID 24055880 DOI: 10.1016/J.Taap.2013.09.007  0.395
2013 Gosavi RA, Knudsen GA, Birnbaum LS, Pedersen LC. Mimicking of estradiol binding by flame retardants and their metabolites: a crystallographic analysis. Environmental Health Perspectives. 121: 1194-9. PMID 23959441 DOI: 10.1289/Ehp.1306902  0.334
2013 Lam T, Williams PL, Burns JS, Sergeyev O, Korrick SA, Lee MM, Birnbaum LS, Revich B, Altshul LM, Patterson DG, Turner WE, Hauser R. Predictors of serum chlorinated pesticide concentrations among prepubertal Russian boys. Environmental Health Perspectives. 121: 1372-7. PMID 23955839 DOI: 10.1289/Ehp.1306480  0.353
2013 Birnbaum LS, Aungst J, Schug TT, Goodman JL. Working together: research- and science-based regulation of BPA. Environmental Health Perspectives. 121: A206-7. PMID 23817036 DOI: 10.1289/Ehp.1306963  0.35
2013 Sanders JM, Knudsen GA, Birnbaum LS. The fate of β-hexabromocyclododecane in female C57BL/6 mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 134: 251-7. PMID 23733921 DOI: 10.1093/Toxsci/Kft121  0.407
2013 Birnbaum LS. State of the science of endocrine disruptors. Environmental Health Perspectives. 121: A107. PMID 23548815 DOI: 10.1289/Ehp.1306695  0.366
2013 Carlin DJ, Rider CV, Woychik R, Birnbaum LS. Unraveling the health effects of environmental mixtures: an NIEHS priority. Environmental Health Perspectives. 121: A6-8. PMID 23409283 DOI: 10.1289/Ehp.1206182  0.367
2013 Schug TT, Johnson AF, Balshaw DM, Garantziotis S, Walker NJ, Weis C, Nadadur SS, Birnbaum LS. ONE Nano: NIEHS's strategic initiative on the health and safety effects of engineered nanomaterials. Environmental Health Perspectives. 121: 410-4. PMID 23407114 DOI: 10.1289/Ehp.1206091  0.307
2013 Birnbaum LS. Designing safer chemicals. Environmental Health Perspectives. 121: A9. PMID 23287533 DOI: 10.1289/Ehp.1206349  0.339
2012 Hakk H, Szabo DT, Huwe J, Diliberto J, Birnbaum LS. Novel and distinct metabolites identified following a single oral dose of α- or γ-hexabromocyclododecane in mice. Environmental Science & Technology. 46: 13494-503. PMID 23171393 DOI: 10.1021/es303209g  0.723
2012 Birnbaum LS. NIEHS's new strategic plan. Environmental Health Perspectives. 120: a298. PMID 22853936 DOI: 10.1289/Ehp.1205642  0.332
2012 Schecter A, Szabo DT, Miller J, Gent TL, Malik-Bass N, Petersen M, Paepke O, Colacino JA, Hynan LS, Harris TR, Malla S, Birnbaum LS. Hexabromocyclododecane (HBCD) stereoisomers in U.S. food from Dallas, Texas. Environmental Health Perspectives. 120: 1260-4. PMID 22647707 DOI: 10.1289/Ehp.1204993  0.682
2012 Birnbaum LS. Environmental chemicals: evaluating low-dose effects. Environmental Health Perspectives. 120: A143-4. PMID 22470049 DOI: 10.1289/Ehp.1205179  0.392
2012 Szabo D, Shah R, Sumner S, Birnbaum L. Systems biology approach for better understanding of mechanisms of neurodevelopment toxicity: A case study using the major flame retardant HBCD Neurotoxicology and Teratology. 34: 379. DOI: 10.1016/J.Ntt.2012.05.036  0.66
2011 Humblet O, Williams PL, Korrick SA, Sergeyev O, Emond C, Birnbaum LS, Burns JS, Altshul L, Patterson DG, Turner WE, Lee MM, Revich B, Hauser R. Dioxin and polychlorinated biphenyl concentrations in mother's serum and the timing of pubertal onset in sons. Epidemiology (Cambridge, Mass.). 22: 827-35. PMID 21968773 DOI: 10.1097/Ede.0B013E318230B0D1  0.346
2011 Szabo DT, Diliberto JJ, Huwe JK, Birnbaum LS. Differences in tissue distribution of HBCD alpha and gamma between adult and developing mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 256-63. PMID 21705717 DOI: 10.1093/Toxsci/Kfr161  0.747
2011 Bucher JR, Thayer K, Birnbaum LS. The Office of Health Assessment and Translation: a problem-solving resource for the National Toxicology Program. Environmental Health Perspectives. 119: A196-7. PMID 21531652 DOI: 10.1289/Ehp.1103645  0.343
2011 Szabo DT, Diliberto JJ, Hakk H, Huwe JK, Birnbaum LS. Toxicokinetics of the flame retardant hexabromocyclododecane alpha: effect of dose, timing, route, repeated exposure, and metabolism. Toxicological Sciences : An Official Journal of the Society of Toxicology. 121: 234-44. PMID 21441408 DOI: 10.1093/toxsci/kfr059  0.728
2011 Babrauskas V, Blum A, Daley R, Birnbaum L. Flame Retardants in Furniture Foam: Benefits and Risks Fire Safety Science. 10: 265-278. DOI: 10.3801/Iaffs.Fss.10-265  0.301
2010 Shaw SD, Blum A, Weber R, Kannan K, Rich D, Lucas D, Koshland CP, Dobraca D, Hanson S, Birnbaum LS. Halogenated flame retardants: do the fire safety benefits justify the risks? Reviews On Environmental Health. 25: 261-305. PMID 21268442 DOI: 10.1515/Reveh.2010.25.4.261  0.367
2010 Birnbaum LS, Jung P. Evolution in environmental health: incorporating the infectious disease paradigm. Environmental Health Perspectives. 118: a327-8. PMID 20675264 DOI: 10.1289/Ehp.1002661  0.323
2010 Humblet O, Williams PL, Korrick SA, Sergeyev O, Emond C, Birnbaum LS, Burns JS, Altshul L, Patterson DG, Turner WE, Lee MM, Revich B, Hauser R. Predictors of serum dioxin, furan, and PCB concentrations among women from Chapaevsk, Russia. Environmental Science & Technology. 44: 5633-40. PMID 20578718 DOI: 10.1021/Es100976J  0.338
2010 Szabo DT, Diliberto JJ, Hakk H, Huwe JK, Birnbaum LS. Toxicokinetics of the flame retardant hexabromocyclododecane gamma: effect of dose, timing, route, repeated exposure, and metabolism. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 282-93. PMID 20562218 DOI: 10.1093/toxsci/kfq183  0.742
2010 La Merrill M, Harper R, Birnbaum LS, Cardiff RD, Threadgill DW. Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice. Environmental Health Perspectives. 118: 596-601. PMID 20435547 DOI: 10.1289/Ehp.0901047  0.361
2010 Birnbaum LS. Applying research to public health questions: biologically relevant exposures. Environmental Health Perspectives. 118: A152. PMID 20368121 DOI: 10.1289/Ehp.1002015  0.329
2010 Birnbaum LS. TSCA reform under way in Congress. Environmental Health Perspectives. 118: A 106. PMID 20197245 DOI: 10.1289/Ehp.1001917  0.304
2010 Emond C, Raymer JH, Studabaker WB, Garner CE, Birnbaum LS. A physiologically based pharmacokinetic model for developmental exposure to BDE-47 in rats. Toxicology and Applied Pharmacology. 242: 290-8. PMID 19883674 DOI: 10.1016/J.Taap.2009.10.019  0.388
2010 Schecter A, Colacino JA, Shah N, Päpke O, Opel M, Patel K, Birnbaum LS. Indoor and outdoor air PBDE levels in a Southwestern US city Toxicological & Environmental Chemistry. 92: 1053-1063. DOI: 10.1080/02772240903306359  0.341
2009 Birnbaum LS. Applying research to public health questions: timing and the environmentally relevant dose. Environmental Health Perspectives. 117: A478. PMID 20049095 DOI: 10.1289/Ehp.0901417  0.409
2009 La Merrill M, Kuruvilla BS, Pomp D, Birnbaum LS, Threadgill DW. Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors. Environmental Health Perspectives. 117: 1414-9. PMID 19750107 DOI: 10.1289/Ehp.0800530  0.377
2009 Scott LL, Staskal DF, Williams ES, Luksemburg WJ, Urban JD, Nguyen LM, Haws LC, Birnbaum LS, Paustenbach DJ, Harris MA. Levels of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in southern Mississippi catfish and estimation of potential health risks. Chemosphere. 74: 1002-10. PMID 19108868 DOI: 10.1016/J.Chemosphere.2008.09.090  0.785
2009 Szabo DT, Richardson VM, Ross DG, Diliberto JJ, Kodavanti PR, Birnbaum LS. Effects of perinatal PBDE exposure on hepatic phase I, phase II, phase III, and deiodinase 1 gene expression involved in thyroid hormone metabolism in male rat pups. Toxicological Sciences : An Official Journal of the Society of Toxicology. 107: 27-39. PMID 18978342 DOI: 10.1093/Toxsci/Kfn230  0.736
2009 La Merrill M, Baston DS, Denison MS, Birnbaum LS, Pomp D, Threadgill DW. Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. American Journal of Physiology. Endocrinology and Metabolism. 296: E203-10. PMID 18840765 DOI: 10.1152/Ajpendo.90368.2008  0.316
2008 Woodruff TJ, Zeise L, Axelrad DA, Guyton KZ, Janssen S, Miller M, Miller GG, Schwartz JM, Alexeeff G, Anderson H, Birnbaum L, Bois F, Cogliano VJ, Crofton K, Euling SY, et al. Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making. Environmental Health Perspectives. 116: 1568-75. PMID 19057713 DOI: 10.1289/Ehp.11516  0.347
2008 Huwe JK, Hakk H, Birnbaum LS. Tissue distribution of polybrominated diphenyl ethers in male rats and implications for biomonitoring. Environmental Science & Technology. 42: 7018-24. PMID 18853825 DOI: 10.1021/Es801344A  0.333
2008 Staskal DF, Scott LL, Haws LC, Luksemburg WJ, Birnbaum LS, Urban JD, Williams ES, Paustenbach DJ, Harris MA. Assessment of polybrominated diphenyl ether exposures and health risks associated with consumption of southern Mississippi catfish. Environmental Science & Technology. 42: 6755-61. PMID 18800560 DOI: 10.1021/Es800613K  0.78
2008 Jeong YC, Walker NJ, Burgin DE, Kissling G, Gupta M, Kupper L, Birnbaum LS, Swenberg JA. Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons. Free Radical Biology & Medicine. 45: 585-91. PMID 18534201 DOI: 10.1016/J.Freeradbiomed.2008.04.043  0.803
2008 Huwe JK, Hakk H, Smith DJ, Diliberto JJ, Richardson V, Stapleton HM, Birnbaum LS. Comparative absorption and bioaccumulation of polybrominated diphenyl ethers following ingestion via dust and oil in male rats. Environmental Science & Technology. 42: 2694-700. PMID 18505018 DOI: 10.1021/Es702644K  0.388
2008 Weintraub M, Birnbaum LS. Catfish consumption as a contributor to elevated PCB levels in a non-Hispanic black subpopulation. Environmental Research. 107: 412-7. PMID 18407261 DOI: 10.1016/J.Envres.2008.03.001  0.357
2008 Birnbaum LS. The effect of environmental chemicals on human health. Fertility and Sterility. 89: e31. PMID 18308056 DOI: 10.1016/J.Fertnstert.2007.12.022  0.308
2008 Smialowicz RJ, DeVito MJ, Williams WC, Birnbaum LS. Relative potency based on hepatic enzyme induction predicts immunosuppressive effects of a mixture of PCDDS/PCDFS and PCBS Toxicology and Applied Pharmacology. 227: 477-484. PMID 18190939 DOI: 10.1016/J.Taap.2007.11.018  0.428
2008 Richardson VM, Staskal DF, Ross DG, Diliberto JJ, DeVito MJ, Birnbaum LS. Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. Toxicology and Applied Pharmacology. 226: 244-50. PMID 17964624 DOI: 10.1016/J.Taap.2007.09.015  0.794
2007 Dye JA, Venier M, Zhu L, Ward CR, Hites RA, Birnbaum LS. Elevated PBDE levels in pet cats: sentinels for humans? Environmental Science & Technology. 41: 6350-6. PMID 17948778 DOI: 10.1021/Es0708159  0.319
2007 vom Saal FS, Akingbemi BT, Belcher SM, Birnbaum LS, Crain DA, Eriksen M, Farabollini F, Guillette LJ, Hauser R, Heindel JJ, Ho SM, Hunt PA, Iguchi T, Jobling S, Kanno J, et al. Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reproductive Toxicology (Elmsford, N.Y.). 24: 131-8. PMID 17768031 DOI: 10.1016/J.Reprotox.2007.07.005  0.347
2007 Richter CA, Birnbaum LS, Farabollini F, Newbold RR, Rubin BS, Talsness CE, Vandenbergh JG, Walser-Kuntz DR, vom Saal FS. In vivo effects of bisphenol A in laboratory rodent studies. Reproductive Toxicology (Elmsford, N.Y.). 24: 199-224. PMID 17683900 DOI: 10.1016/J.Reprotox.2007.06.004  0.409
2006 Birnbaum LS, Cohen Hubal EA. Polybrominated diphenyl ethers: a case study for using biomonitoring data to address risk assessment questions. Environmental Health Perspectives. 114: 1770-5. PMID 17107866 DOI: 10.1289/Ehp.9061  0.359
2006 Emond C, Birnbaum LS, DeVito MJ. Use of a physiologically based pharmacokinetic model for rats to study the influence of body fat mass and induction of CYP1A2 on the pharmacokinetics of TCDD. Environmental Health Perspectives. 114: 1394-400. PMID 16966094 DOI: 10.1289/Ehp.8805  0.373
2006 Staskal DF, Hakk H, Bauer D, Diliberto JJ, Birnbaum LS. Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 94: 28-37. PMID 16936226 DOI: 10.1093/Toxsci/Kfl091  0.804
2006 Van den Berg M, Birnbaum LS, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws L, Rose M, Safe S, Schrenk D, Tohyama C, Tritscher A, et al. The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 223-41. PMID 16829543 DOI: 10.1093/Toxsci/Kfl055  0.385
2006 Schecter A, Birnbaum L, Ryan JJ, Constable JD. Dioxins: an overview. Environmental Research. 101: 419-28. PMID 16445906 DOI: 10.1016/J.Envres.2005.12.003  0.325
2006 Staskal DF, Diliberto JJ, Birnbaum LS. Disposition of BDE 47 in developing mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 90: 309-16. PMID 16407092 DOI: 10.1093/Toxsci/Kfj098  0.799
2006 Staskal DF, Diliberto JJ, Birnbaum LS. Impact of repeated exposure on the toxicokinetics of BDE 47 in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 89: 380-5. PMID 16280385 DOI: 10.1093/Toxsci/Kfj038  0.815
2006 Haws LC, Su SH, Harris M, DeVito MJ, Walker NJ, Farland WH, Finley B, Birnbaum LS. Development of a refined database of mammalian relative potency estimates for dioxin-like compounds Toxicological Sciences. 89: 4-30. PMID 16120753 DOI: 10.1093/Toxsci/Kfi294  0.324
2005 Emond C, Michalek JE, Birnbaum LS, DeVito MJ. Comparison of the use of a physiologically based pharmacokinetic model and a classical pharmacokinetic model for dioxin exposure assessments. Environmental Health Perspectives. 113: 1666-8. PMID 16330344 DOI: 10.1289/Ehp.8016  0.38
2005 Windal I, Denison MS, Birnbaum LS, Van Wouwe N, Baeyens W, Goeyens L. Chemically activated luciferase gene expression (CALUX) cell bioassay analysis for the estimation of dioxin-like activity: critical parameters of the CALUX procedure that impact assay results. Environmental Science & Technology. 39: 7357-64. PMID 16245802 DOI: 10.1021/Es0504993  0.304
2005 Kodavanti PRS, Ward TR, Ludewig G, Robertson LW, Birnbaum LS. Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships Toxicological Sciences. 88: 181-192. PMID 16107548 DOI: 10.1093/Toxsci/Kfi289  0.365
2005 Van Larebeke NA, Birnbaum LS, Boogaerts MA, Bracke M, Davis DL, Demarini DM, Hooper K, Huff J, Kleinjans JC, Legator MS, Schoeters G, Vähäkangas K. Unrecognized or potential risk factors for childhood cancer. International Journal of Occupational and Environmental Health. 11: 199-201. PMID 15875896 DOI: 10.1179/Oeh.2005.11.2.199  0.329
2005 Staskal DF, Diliberto JJ, Devito MJ, Birnbaum LS. Inhibition of human and rat CYP1A2 by TCDD and dioxin-like chemicals. Toxicological Sciences : An Official Journal of the Society of Toxicology. 84: 225-31. PMID 15659567 DOI: 10.1093/Toxsci/Kfi090  0.779
2005 Schecter A, Päpke O, Tung KC, Staskal D, Birnbaum L. Polybrominated diphenyl ethers contamination of United States food. Environmental Science & Technology. 38: 5306-11. PMID 15543730 DOI: 10.1021/Es0490830  0.758
2005 Staskal DF, Diliberto JJ, DeVito MJ, Birnbaum LS. Toxicokinetics of BDE 47 in female mice: effect of dose, route of exposure, and time. Toxicological Sciences : An Official Journal of the Society of Toxicology. 83: 215-23. PMID 15509665 DOI: 10.1093/Toxsci/Kfi018  0.812
2005 Schecter A, Tung K, Päpke O, Staskal D, Birnbaum L. Response to Comments on “Polybrominated Diphenyl Ethers Contamination of United States Food” Environmental Science & Technology. 39: 2415-2416. DOI: 10.1021/Es058001K  0.743
2004 Emond C, Birnbaum LS, DeVito MJ. Physiologically based pharmacokinetic model for developmental exposures to TCDD in the rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 115-33. PMID 15056810 DOI: 10.1093/Toxsci/Kfh117  0.394
2004 Smialowicz RJ, Burgin DE, Williams WC, Diliberto JJ, Setzer RW, Birnbaum LS. CYP1A2 is not required for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunosuppression. Toxicology. 197: 15-22. PMID 15003330 DOI: 10.1016/J.Tox.2003.11.016  0.795
2004 Badr MZ, Birnbaum LS. Enhanced potential for oxidative stress in livers of senescent rats by the peroxisome proliferator-activated receptor alpha agonist perfluorooctanoic acid. Mechanisms of Ageing and Development. 125: 69-75. PMID 14706239 DOI: 10.1016/J.Mad.2003.10.006  0.324
2004 Birnbaum LS, Staskal DF. Brominated flame retardants: cause for concern? Environmental Health Perspectives. 112: 9-17. PMID 14698924 DOI: 10.1289/Ehp.6559  0.76
2004 Schecter A, Pavuk M, Päpke O, Ryan JJ, Birnbaum L, Rosen R. Polybrominated diphenyl ethers (PBDEs) in U.S. mothers' milk. Environmental Health Perspectives. 111: 1723-9. PMID 14594622 DOI: 10.1289/Ehp.6466  0.345
2003 Birnbaum LS, Staskal DF, Diliberto JJ. Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs). Environment International. 29: 855-60. PMID 12850101 DOI: 10.1016/S0160-4120(03)00106-5  0.789
2003 Hamm JT, Chen CY, Birnbaum LS. A mixture of dioxins, furans, and non-ortho PCBs based upon consensus toxic equivalency factors produces dioxin-like reproductive effects. Toxicological Sciences : An Official Journal of the Society of Toxicology. 74: 182-91. PMID 12730615 DOI: 10.1093/Toxsci/Kfg107  0.416
2003 Birnbaum LS, Fenton SE. Cancer and developmental exposure to endocrine disruptors. Environmental Health Perspectives. 111: 389-94. PMID 12676588 DOI: 10.1289/Ehp.5686  0.366
2002 Chen CY, Hamm JT, Hass JR, Albro PW, Birnbaum LS. A mixture of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and non-ortho polychlorinated biphenyls (PCBs) changed the lipid content of pregnant Long Evans rats. Chemosphere. 46: 1501-4. PMID 12002482 DOI: 10.1016/S0045-6535(01)00271-5  0.337
2002 Slezak BP, Hamm JT, Reyna J, Hurst CH, Birnbaum LS. TCDD-mediated oxidative stress in male rat pups following perinatal exposure Journal of Biochemical and Molecular Toxicology. 16: 49-52. PMID 11979421 DOI: 10.1002/Jbt.10024  0.389
2002 Fenton SE, Hamm JT, Birnbaum LS, Youngblood GL. Persistent abnormalities in the rat mammary gland following gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicological Sciences : An Official Journal of the Society of Toxicology. 67: 63-74. PMID 11961217 DOI: 10.1093/Toxsci/67.1.63  0.366
2002 Birnbaum LS, Cummings AM. Dioxins and endometriosis: A plausible hypothesis Environmental Health Perspectives. 110: 15-21. PMID 11781160 DOI: 10.1289/Ehp.0211015  0.337
2002 Hurst CH, Abbott B, Schmid JE, Birnbaum LS. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disrupts early morphogenetic events that form the lower reproductive tract in female rat fetuses. Toxicological Sciences : An Official Journal of the Society of Toxicology. 65: 87-98. PMID 11752688 DOI: 10.1093/Toxsci/65.1.87  0.318
2001 Burgin DE, Diliberto JJ, Derr-Yellin EC, Kannan N, Kodavanti PR, Birnbaum LS. Differential effects of two lots of aroclor 1254 on enzyme induction, thyroid hormones, and oxidative stress. Environmental Health Perspectives. 109: 1163-8. PMID 11713002 DOI: 10.1289/Ehp.011091163  0.783
2001 Kodavanti PR, Kannan N, Yamashita N, Derr-Yellin EC, Ward TR, Burgin DE, Tilson HA, Birnbaum LS. Differential effects of two lots of aroclor 1254: congener-specific analysis and neurochemical end points. Environmental Health Perspectives. 109: 1153-61. PMID 11713001 DOI: 10.1289/Ehp.011091153  0.766
2001 Chen CY, Hamm JT, Hass JR, Birnbaum LS. Disposition of polychlorinated dibenzo-p-dioxins, dibenzofurans, and non-ortho polychlorinated biphenyls in pregnant long evans rats and the transfer to offspring. Toxicology and Applied Pharmacology. 173: 65-88. PMID 11384209 DOI: 10.1006/Taap.2001.9143  0.417
2001 Diliberto JJ, DeVito MJ, Ross DG, Birnbaum LS. Subchronic Exposure of [3H]- 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female B6C3F1 mice: relationship of steady-state levels to disposition and metabolism. Toxicological Sciences : An Official Journal of the Society of Toxicology. 61: 241-55. PMID 11353133 DOI: 10.1093/Toxsci/61.2.241  0.436
2000 Hurst CH, DeVito MJ, Birnbaum LS. Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing long-evans rats following subchronic exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 57: 275-83. PMID 11006357 DOI: 10.1093/Toxsci/57.2.275  0.405
2000 DeVito MJ, Ménache MG, Diliberto JJ, Ross DG, Birnbaum LS. Dose-response relationships for induction of CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin in female mice following subchronic exposure to polychlorinated biphenyls. Toxicology and Applied Pharmacology. 167: 157-72. PMID 10986007 DOI: 10.1006/Taap.2000.9010  0.428
2000 Birnbaum LS, Tuomisto J. Non-carcinogenic effects of TCDD in animals. Food Additives and Contaminants. 17: 275-88. PMID 10912242 DOI: 10.1080/026520300283351  0.393
2000 Wang X, Santostefano MJ, DeVito MJ, Birnbaum LS. Extrapolation of a PBPK model for dioxins across dosage regimen, gender, strain, and species. Toxicological Sciences : An Official Journal of the Society of Toxicology. 56: 49-60. PMID 10869453 DOI: 10.1093/Toxsci/56.1.49  0.32
2000 Slezak BP, Hatch GE, DeVito MJ, Diliberto JJ, Slade R, Crissman K, Hassoun E, Birnbaum LS. Oxidative stress in female B6C3F1 mice following acute and subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicological Sciences : An Official Journal of the Society of Toxicology. 54: 390-8. PMID 10774821 DOI: 10.1093/Toxsci/54.2.390  0.464
2000 Hurst CH, DeVito MJ, Setzer RW, Birnbaum LS. Acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in pregnant Long Evans rats: association of measured tissue concentrations with developmental effects. Toxicological Sciences : An Official Journal of the Society of Toxicology. 53: 411-20. PMID 10696789 DOI: 10.1093/Toxsci/53.2.411  0.413
1999 Cummings AM, Hedge JM, Birnbaum LS. Effect of prenatal exposure to TCDD on the promotion of endometriotic lesion growth by TCDD in adult female rats and mice Toxicological Sciences. 52: 45-49. PMID 10568697 DOI: 10.1093/Toxsci/52.1.45  0.361
1999 Santostefano MJ, Richardson VM, Walker NJ, Blanton J, Lindros KO, Lucier GW, Alcasey SK, Birnbaum LS. Dose-dependent localization of TCDD in isolated centrilobular and periportal hepatocytes Toxicological Sciences. 52: 9-19. PMID 10568693 DOI: 10.1093/Toxsci/52.1.9  0.404
1999 Slezak BP, Diliberto JJ, Birnbaum LS. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated oxidative stress in CYP1A2 knockout (CYP1A2-/-) mice. Biochemical and Biophysical Research Communications. 264: 376-9. PMID 10529372 DOI: 10.1006/Bbrc.1999.1518  0.338
1999 Diliberto JJ, Burgin DE, Birnbaum LS. Effects of CYP1A2 on disposition of 2,3,7, 8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8-pentachlorodibenzofuran, and 2,2',4,4',5,5'-hexachlorobiphenyl in CYP1A2 knockout and parental (C57BL/6N and 129/Sv) strains of mice. Toxicology and Applied Pharmacology. 159: 52-64. PMID 10448125 DOI: 10.1006/Taap.1999.8720  0.787
1999 Brouwer A, Longnecker MP, Birnbaum LS, Cogliano J, Kostyniak P, Moore J, Schantz S, Winneke G. Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs. Environmental Health Perspectives. 639-49. PMID 10421775 DOI: 10.1289/ehp.99107s4639  0.31
1999 Hamm JT, Ross DG, Richardson VM, Diliberto JJ, Birnbaum LS. Methoxyresorufin: an inappropriate substrate for CYP1A2 in the mouse. Biochemical Pharmacology. 56: 1657-60. PMID 9973187 DOI: 10.1016/S0006-2952(98)00241-X  0.351
1999 Brouwer A, Longnecker MP, Birnbaum LS, Cogliano J, Kostyniak P, Moore J, Schantz S, Winneke G. Characterization of Potential Endocrine-Related Health Effects at Low-Dose Levels of Exposure to PCBs Environmental Health Perspectives. 107: 639. DOI: 10.2307/3434557  0.38
1998 DeVito MJ, Ross DG, Dupuy AE, Ferrario J, McDaniel D, Birnbaum LS. Dose-response relationships for disposition and hepatic sequestration of polyhalogenated dibenzo-p-dioxins, dibenzofurans, and biphenyls following subchronic treatment in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 46: 223-34. PMID 10048125 DOI: 10.1006/Toxs.1998.2530  0.445
1998 Santostefano MJ, Wang X, Richardson VM, Ross DG, DeVito MJ, Birnbaum LS. A pharmacodynamic analysis of TCDD-induced cytochrome P450 gene expression in multiple tissues: dose- and time-dependent effects. Toxicology and Applied Pharmacology. 151: 294-310. PMID 9707506 DOI: 10.1006/Taap.1998.8466  0.377
1998 Viluksela M, Stahl BU, Birnbaum LS, Rozman KK. Subchronic/chronic toxicity of a mixture of four chlorinated dibenzo-p-dioxins in rats. II. Biochemical effects. Toxicology and Applied Pharmacology. 151: 70-8. PMID 9705888 DOI: 10.1006/Taap.1998.8412  0.381
1998 Pollenz RS, Santostefano MJ, Klett E, Richardson VM, Necela B, Birnbaum LS. Female Sprague-Dawley rats exposed to a single oral dose of 2,3,7,8- tetrachlorodibenzo-p-dioxin exhibit sustained depletion of aryl hydrocarbon receptor protein in liver, spleen, thymus, and lung Toxicological Sciences. 42: 117-128. PMID 9579024 DOI: 10.1006/Toxs.1998.2439  0.368
1998 Hassoun EA, Wilt SC, Devito MJ, Van Birgelen A, Alsharif NZ, Birnbaum LS, Stohs SJ. Induction of oxidative stress in brain tissues of mice after subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicological Sciences : An Official Journal of the Society of Toxicology. 42: 23-7. PMID 9538044 DOI: 10.1006/Toxs.1997.2411  0.371
1998 DeVito MJ, Diliberto JJ, Ross DG, Menache MG, Birnbaum LS. Dose-response relationships for polyhalogenated dioxins and dibenzofurans following subchronic treatment in mice. I. CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin. Toxicology and Applied Pharmacology. 147: 267-80. PMID 9439722 DOI: 10.1006/Taap.1997.8261  0.395
1998 Hurst CH, Abbott BD, DeVito MJ, Birnbaum LS. 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Pregnant Long Evans Rats: Disposition to Maternal and Embryo/Fetal Tissues Toxicological Sciences. 45: 129-136. DOI: 10.1093/Toxsci/45.2.129  0.394
1997 Wang X, Santostefano MJ, Evans MV, Richardson VM, Diliberto JJ, Birnbaum LS. Determination of parameters responsible for pharmacokinetic behavior of TCDD in female Sprague-Dawley rats Toxicology and Applied Pharmacology. 147: 151-168. PMID 9356318 DOI: 10.1006/Taap.1997.8242  0.369
1997 Viluksela M, Stahl BU, Birnbaum LS, Rozman KK. Subchronic/chronic toxicity of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD) in rats. Part II. Biochemical effects. Toxicology and Applied Pharmacology. 146: 217-26. PMID 9344889 DOI: 10.1006/Taap.1997.8240  0.368
1997 Viluksela M, Stahl BU, Birnbaum LS, Schramm KW, Kettrup A, Rozman KK. Subchronic/chronic toxicity of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD) in rats. Part I. Design, general observations, hematology, and liver concentrations. Toxicology and Applied Pharmacology. 146: 207-16. PMID 9344888 DOI: 10.1006/Taap.1997.8239  0.366
1997 Johnson KL, Cummings AM, Birnbaum LS. Promotion of endometriosis in mice by polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls. Environmental Health Perspectives. 105: 750-5. PMID 9294722 DOI: 10.1289/Ehp.97105750  0.383
1997 Diliberto JJ, Burgin D, Birnbaum LS. Role of CYP1A2 in hepatic sequestration of dioxin: studies using CYP1A2 knock-out mice. Biochemical and Biophysical Research Communications. 236: 431-3. PMID 9240455 DOI: 10.1006/Bbrc.1997.6973  0.777
1997 Andersen ME, Birnbaum LS, Barton HA, Eklund CR. Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin evaluated with a multicompartment geometric model of hepatic zonation. Toxicology and Applied Pharmacology. 144: 145-55. PMID 9169078 DOI: 10.1006/Taap.1996.8067  0.318
1997 Andersen ME, Eklund CR, Mills JJ, Barton HA, Birnbaum LS. A multicompartment geometric model of the liver in relation to regional induction of cytochrome P450s. Toxicology and Applied Pharmacology. 144: 135-44. PMID 9169077 DOI: 10.1006/Taap.1996.8066  0.31
1997 Santostefano MJ, Ross DG, Savas U, Jefcoate CR, Birnbaum LS. Differential time-course and dose-response relationships of TCDD-induced CYP1B1, CYP1A1, and CYP1A2 proteins in rats Biochemical and Biophysical Research Communications. 233: 20-24. PMID 9144388 DOI: 10.1006/Bbrc.1997.6389  0.364
1997 Simalowicz RJ, DeVito MJ, Riddle MM, Williams WC, Birnbaum LS. Opposite Effects of 2,2′,4,4′,5,5′-Hexachlorobiphenyl and 2,3,7,8-Tetrachlorodibenzo-p-dioxin on the Antibody Response to Sheep Erythrocytes in Mice Toxicological Sciences. 37: 141-149. DOI: 10.1093/Toxsci/37.2.141  0.403
1996 van Birgelen AP, DeVito MJ, Akins JM, Ross DG, Diliberto JJ, Birnbaum LS. Relative potencies of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls derived from hepatic porphyrin accumulation in mice. Toxicology and Applied Pharmacology. 138: 98-109. PMID 8658519 DOI: 10.1006/Taap.1996.0103  0.411
1996 Diliberto JJ, Jackson JA, Birnbaum LS. Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disposition following pulmonary, oral, dermal, and parenteral exposures to rats. Toxicology and Applied Pharmacology. 138: 158-68. PMID 8658505 DOI: 10.1006/Taap.1996.0109  0.423
1996 Cummings AM, Metcalf JL, Birnbaum L. Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice: time-dose dependence and species comparison. Toxicology and Applied Pharmacology. 138: 131-9. PMID 8658502 DOI: 10.1006/Taap.1996.0106  0.361
1996 Birnbaum LS. Developmental effects of dioxins. Environmental Health Perspectives. 89-94. PMID 8593882 DOI: 10.1289/Ehp.95103S789  0.306
1996 SANTOSTEFANO MJ, JOHNSON KL, WHISNANT NA, RICHARDSON VM, DEVITO MJ, BIRNBAUM LS. Subcellular Localization of TCDD Differs between the Liver, Lungs, and Kidneys after Acute and Subchronic Exposure: Species/Dose Comparisons and Possible Mechanism Toxicological Sciences. 34: 265-275. DOI: 10.1093/Toxsci/34.2.265  0.413
1996 Abbott B, Birnbaum L, Diliberto J. Rapid distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to embryonic tissues in C57BL/6N mice and correlation with palatal uptake in vitro Toxicology and Applied Pharmacology. 141: 256-263. DOI: 10.1016/S0041-008X(96)80031-7  0.429
1996 VAN BIRGELEN APJM, ROSS DG, DEVITO MJ, BIRNBAUM LS. Interactive Effects between 2,3,7,8-Tetrachlorodibenzo-p-dioxin and 2,2′,4,4′,5,5′-Hexachlorobiphenyl in Female B6C3F1 Mice: Tissue Distribution and Tissue-Specific Enzyme Induction Toxicological Sciences. 34: 118-131. DOI: 10.1006/Faat.1996.0182  0.404
1996 BURLESON GR, LEBREC H, YANG YG, IBANES JD, PENNINGTON KN, BIRNBAUM LS. Effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on Influenza Virus Host Resistance in Mice Toxicological Sciences. 29: 40-47. DOI: 10.1006/Faat.1996.0004  0.306
1995 Bull RJ, Birnbaum LS, Cantor KP, Rose JB, Butterworth BE, Pegram R, Tuomisto J. Water chlorination: essential process or cancer hazard? Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 28: 155-66. PMID 8835225 DOI: 10.1006/Faat.1995.1156  0.308
1995 Birnbaum LS. Developmental effects of dioxins and related endocrine disrupting chemicals Toxicology Letters. 82: 743-750. PMID 8597137 DOI: 10.1016/0378-4274(95)03592-3  0.306
1995 Birnbaum LS, DeVito MJ. Use of toxic equivalency factors for risk assessment for dioxins and related compounds Toxicology. 105: 391-401. PMID 8571375 DOI: 10.1016/0300-483X(95)03237-A  0.357
1995 McMahon TF, Medinsky MA, Birnbaum LS. Age-related changes in benzene disposition in male C57BL/6N mice described by a physiologically based pharmacokinetic model. Toxicology Letters. 74: 241-53. PMID 7871548 DOI: 10.1016/0378-4274(94)90083-3  0.373
1995 Diliberto JJ, Akubue PI, Luebke RW, Birnbaum LS. Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice. Toxicology and Applied Pharmacology. 130: 197-208. PMID 7871533 DOI: 10.1006/Taap.1995.1025  0.402
1995 Pegram RA, Diliberto JJ, Moore TC, Gao P, Birnbaum LS. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) distribution and cytochrome P4501A induction in young adult and senescent male mice. Toxicology Letters. 76: 119-26. PMID 7725343 DOI: 10.1016/0378-4274(94)03212-P  0.412
1995 De Jongh J, DeVito M, Nieboer R, Birnbaum L, Van den Berg M. Induction of cytochrome P450 isoenzymes after toxicokinetic interactions between 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,2',4,4',5,5'-hexachlorobiphenyl in the liver of the mouse. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 25: 264-70. PMID 7665010 DOI: 10.1006/Faat.1995.1062  0.377
1995 Birnbaum LS. Workshop on perinatal exposure to dioxin-like compounds. V. Immunologic effects Environmental Health Perspectives. 103: 157-160. PMID 7614940 DOI: 10.1289/Ehp.95103S2157  0.342
1995 Brouwer A, Ahlborg UG, Van den Berg M, Birnbaum LS, Ruud Boersma E, Bosveld B, Denison MS, Earl Gray L, Hagmar L, Holene E, Huisman M, Jacobson SW, Jacobson JL, Koopman-Esseboom C, Koppe JG, et al. Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants European Journal of Pharmacology: Environmental Toxicology And. 293: 1-40. PMID 7545581 DOI: 10.1016/0926-6917(95)90015-2  0.359
1995 DeVito MJ, Birnbaum LS, Farland WH, Gasiewicz TA. Comparisons of estimated human body burdens of dioxinlike chemicals and TCDD body burdens in experimentally exposed animals Environmental Health Perspectives. 103: 820-831. PMID 7498094 DOI: 10.1289/Ehp.95103820  0.328
1995 De Jongh J, DeVito M, Diliberto J, Van den Berg M, Birnbaum L. The effects of 2,2',4,4',5,5'-hexachlorobiphenyl cotreatment on the disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice. Toxicology Letters. 80: 131-7. PMID 7482580 DOI: 10.1016/0378-4274(95)03387-Z  0.393
1995 DeVito MJ, Birnbaum LS. Dioxins: model chemicals for assessing receptor-mediated toxicity Toxicology. 102: 115-123. PMID 7482546 DOI: 10.1016/0300-483X(95)03040-M  0.351
1995 Devito MJ, Birnbaum LS. The importance of pharmacokinetics in determining the relative potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran Toxicological Sciences. 24: 145-148. DOI: 10.1006/Faat.1995.1016  0.401
1994 DeVito MJ, Ma X, Babish JG, Menache M, Birnbaum LS. Dose-response relationships in mice following subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: CYP1A1, CYP1A2, estrogen receptor, and protein tyrosine phosphorylation. Toxicology and Applied Pharmacology. 124: 82-90. PMID 8291065 DOI: 10.1006/Taap.1994.1011  0.416
1994 Kedderis LB, Jackson JA, Patterson DG, Grainger J, Diliberto JJ, Birnbaum LS. Chemical characterization and disposition studies with 1,2,7,8-tetrabromodibenzofuran in the rat. Journal of Toxicology and Environmental Health. 41: 53-69. PMID 8277526 DOI: 10.1080/15287399409531826  0.395
1994 Luebke RW, Copeland CB, Diliberto JJ, Akubue PI, Andrews DL, Riddle MM, Williams WC, Birnbaum LS. Assessment of host resistance to Trichinella spiralis in mice following preinfection exposure to 2,3,7,8-TCDD Toxicology and Applied Pharmacology. 125: 7-16. PMID 8128497 DOI: 10.1006/Taap.1994.1043  0.371
1994 Birnbaum LS. Endocrine effects of prenatal exposure to PCBs, dioxins, and other xenobiotics: Implications for policy and future research Environmental Health Perspectives. 102: 676-679. PMID 7895708 DOI: 10.1289/Ehp.94102676  0.379
1994 Narasimhan TR, Craig A, Arellano L, Harper N, Howie L, Menache M, Birnbaum L, Safe S. Relative sensitivities of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced Cyp1a-1 and Cyp1a-2 gene expression and immunotoxicity in female B6C3F1 mice. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 23: 598-607. PMID 7867912 DOI: 10.1006/Faat.1994.1146  0.405
1994 Birnbaum LS. The mechanism of dioxin toxicity: Relationship to risk assessment Environmental Health Perspectives. 102: 157-167. PMID 7698077 DOI: 10.1289/Ehp.94102S9157  0.391
1994 Ahlborg U, Becking G, Birnbaum L, Brouwer A, Derks H, Feeley M, Golor G, Hanberg A, Larsen J, Liem A, Safe S, Schlatter C, Waern F, Younes M, Yrjänheikki E. Toxic equivalency factors for dioxin-like PCBs Chemosphere. 28: 1049-1067. DOI: 10.1016/0045-6535(94)90324-7  0.327
1993 Diliberto JJ, Kedderis LB, Jackson JA, Birnbaum LS. Effects of dose and routes of exposure on the disposition of 2,3,7,8-[3H]tetrabromodibenzo-p-dioxin (TBDD) in the rat. Toxicology and Applied Pharmacology. 120: 315-26. PMID 8511802 DOI: 10.1006/Taap.1993.1117  0.395
1993 Anderson YB, Jackson JA, Birnbaum LS. Maturational changes in dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Fischer 344 rats. Toxicology and Applied Pharmacology. 119: 214-20. PMID 8480330 DOI: 10.1006/Taap.1993.1062  0.37
1993 Andersen ME, Mills JJ, Gargas ML, Kedderis L, Birnbaum LS, Neubert D, Greenlee WF. Modeling receptor-mediated processes with dioxin: implications for pharmacokinetics and risk assessment. Risk Analysis : An Official Publication of the Society For Risk Analysis. 13: 25-36. PMID 8383868 DOI: 10.1111/J.1539-6924.1993.Tb00726.X  0.331
1993 Kedderis LB, Mills JJ, Andersen ME, Birnbaum LS. A physiologically based pharmacokinetic model for 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in the rat: tissue distribution and CYP1A induction. Toxicology and Applied Pharmacology. 121: 87-98. PMID 8337704 DOI: 10.1006/Taap.1993.1132  0.359
1993 Birnbaum LS. A brief survey of butadiene health effects: A role for metabolic differences Environmental Health Perspectives. 101: 161-167. PMID 8020440 DOI: 10.1289/Ehp.93101S6161  0.413
1993 DEVITO MJ, MAIER WE, DILIBERTO JJ, BIRNBAUM LS. Comparative Ability of Various PCBs, PCDFs, and TCDD to Induce Cytochrome P450 1A1 and 1A2 Activity Following 4 Weeks of Treatment Toxicological Sciences. 20: 125-130. DOI: 10.1093/Toxsci/20.1.125  0.371
1993 Birnbaum LS. EPA's reassessment of dioxin risk: Directed health research Chemosphere. 27: 469-475. DOI: 10.1016/0045-6535(93)90328-3  0.438
1993 MCKINLEY MK, KEDDERIS LB, BIRNBAUM LS. The Effect to Pretreatment on the Biliary Excretion of 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,7,8-Tetrachlorodibenzofuran, and 3,3',4,4'-Tetrachlorobiphenyl in the Rat Toxicological Sciences. 21: 425-432. DOI: 10.1006/Faat.1993.1118  0.379
1993 KEDDERIS LB, ANDERSEN ME, BIRNBAUM LS. Effect of Dose, Time, and Pretreatement on the Biliary Excretion and Tissue Distribution of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in the Rat Toxicological Sciences. 21: 405-411. DOI: 10.1006/Faat.1993.1115  0.398
1992 Abbott BD, Harris MW, Birnbaum LS. Comparisons of the effects of TCDD and hydrocortisone on growth factor expression provide insight into their interaction in the embryonic mouse palate. Teratology. 45: 35-53. PMID 1731395 DOI: 10.1002/Tera.1420450104  0.333
1992 Bechtold WE, Sun JD, Birnbaum LS, Yin SN, Li GL, Kasicki S, Lucier G, Henderson RF. S-phenylcysteine formation in hemoglobin as a biological exposure index to benzene. Archives of Toxicology. 66: 303-9. PMID 1610291 DOI: 10.1007/Bf01973623  0.38
1992 Kedderis L, Diliberto J, Jackson J, Linko P, Goldstein J, Birnbaum L. Effects of dose and route of exposure on dioxin disposition Chemosphere. 25: 7-10. DOI: 10.1016/0045-6535(92)90467-6  0.417
1991 Sun JD, Medinsky MA, Birnbaum LS, Lucier G, Henderson RF. Benzene hemoglobin adducts in mice and rats: characterization of formation and physiological modeling. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 15: 468-75. PMID 2258011 DOI: 10.1016/0272-0590(90)90033-G  0.304
1991 Couture LA, Abbott BD, Birnbaum LS. A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism. Teratology. 42: 619-27. PMID 2087682 DOI: 10.1002/Tera.1420420606  0.428
1991 Kedderis LB, Diliberto JJ, Birnbaum LS. Disposition and excretion of intravenous 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in rats. Toxicology and Applied Pharmacology. 108: 397-406. PMID 2020967 DOI: 10.1016/0041-008X(91)90086-T  0.403
1991 McMahon TF, Stefanski SA, Wilson RE, Blair PC, Clark AM, Birnbaum LS. Comparative acute nephrotoxicity of salicylic acid, 2,3-dihydroxybenzoic acid, and 2,5-dihydroxybenzoic acid in young and middle aged Fischer 344 rats. Toxicology. 66: 297-311. PMID 2011854 DOI: 10.1016/0300-483X(91)90201-B  0.333
1991 Bond JA, Bechtold WE, Birnbaum LS, Dahl AR, Medinsky MA, Sun JD, Henderson RF. Disposition of inhaled isoprene in B6C3F1 mice. Toxicology and Applied Pharmacology. 107: 494-503. PMID 2000636 DOI: 10.1016/0041-008X(91)90312-3  0.319
1991 Couture-Haws L, Harris MW, McDonald MM, Lockhart AC, Birnbaum LS. Hydronephrosis in mice exposed to TCDD-contaminated breast milk: identification of the peak period of sensitivity and assessment of potential recovery. Toxicology and Applied Pharmacology. 107: 413-28. PMID 2000632 DOI: 10.1016/0041-008X(91)90305-X  0.392
1991 Birnbaum LS, Morrissey RE, Harris MW. Teratogenic effects of 2,3,7,8-tetrabromodibenzo-p-dioxin and three polybrominated dibenzofurans in C57BL/6N mice. Toxicology and Applied Pharmacology. 107: 141-52. PMID 1987653 DOI: 10.1016/0041-008X(91)90338-F  0.314
1991 Kedderis LB, Diliberto JJ, Linko P, Goldstein JA, Birnbaum LS. Disposition of 2,3,7,8-tetrabromodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat: biliary excretion and induction of cytochromes CYP1A1 and CYP1A2. Toxicology and Applied Pharmacology. 111: 163-72. PMID 1949032 DOI: 10.1016/0041-008X(91)90145-5  0.398
1991 Dahl AR, Sun JD, Birnbaum LS, Bond JA, Griffith WC, Mauderly JL, Muggenburg BA, Sabourin PJ, Henderson RF. Toxicokinetics of inhaled 1,3-butadiene in monkeys: comparison to toxicokinetics in rats and mice. Toxicology and Applied Pharmacology. 110: 9-19. PMID 1908146 DOI: 10.1016/0041-008X(91)90285-M  0.316
1990 Dahl AR, Bechtold WE, Bond JA, Henderson RF, Mauderly JL, Muggenburg BA, Sun JD, Birnbaum LS. Species differences in the metabolism and disposition of inhaled 1,3-butadiene and isoprene. Environmental Health Perspectives. 86: 65-9. PMID 2401273 DOI: 10.1289/Ehp.908665  0.423
1990 Couture LA, Harris MW, Birnbaum LS. Characterization of the peak period of sensitivity for the induction of hydronephrosis in C57BL/6N mice following exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 15: 142-50. PMID 2373295 DOI: 10.1016/0272-0590(90)90171-F  0.41
1990 Sabourin PJ, Sun JD, MacGregor JT, Wehr CM, Birnbaum LS, Lucier G, Henderson RF. Effect of repeated benzene inhalation exposures on benzene metabolism, binding to hemoglobin, and induction of micronuclei. Toxicology and Applied Pharmacology. 103: 452-62. PMID 2339418 DOI: 10.1016/0041-008X(90)90318-O  0.331
1990 Hébert CD, Harris MW, Elwell MR, Birnbaum LS. Relative toxicity and tumor-promoting ability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,4,7,8-pentachlorodibenzofuran (PCDF), and 1,2,3,4,7,8-hexachlorodibenzofuran (HCDF) in hairless mice. Toxicology and Applied Pharmacology. 102: 362-77. PMID 2300974 DOI: 10.1016/0041-008X(90)90033-Q  0.325
1990 Medinsky MA, Bechtold WE, Birnbaum LS, Bond JA, Burt DG, Cheng YS, Gillett NA, Gulati DK, Hobbs CH, Pickrell JA. Effect of inhaled azodicarbonamide on F344/N rats and B6C3F1 mice with 2-week and 13-week inhalation exposures. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 15: 308-19. PMID 2227158 DOI: 10.1016/0272-0590(90)90057-Q  0.381
1989 Brewster DW, Uraih LC, Birnbaum LS. The acute toxicity of 2,3,4,7,8-pentachlorodibenzofuran (4PeCDF) in the male Fischer rat. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 11: 236-49. PMID 3220203 DOI: 10.1016/0272-0590(88)90148-0  0.416
1989 Brewster DW, Banks YB, Clark AM, Birnbaum LS. Comparative dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin and three polychlorinated dibenzofurans. Toxicology and Applied Pharmacology. 97: 156-66. PMID 2916232 DOI: 10.1016/0041-008X(89)90064-1  0.307
1989 Henderson RF, Sabourin PJ, Bechtold WE, Griffith WC, Medinsky MA, Birnbaum LS, Lucier GW. The effect of dose, dose rate, route of administration, and species on tissue and blood levels of benzene metabolites Environmental Health Perspectives. 82: 9-17. PMID 2792053 DOI: 10.1289/Ehp.89829  0.439
1989 Medinsky MA, Sabourin PJ, Henderson RF, Lucier G, Birnbaum LS. Differences in the pathways for metabolism of benzene in rats and mice simulated by a physiological model. Environmental Health Perspectives. 82: 43-9. PMID 2792050 DOI: 10.1289/Ehp.898243  0.388
1989 Abbott BD, Diliberto JJ, Birnbaum LS. 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters embryonic palatal medial epithelial cell differentiation in vitro. Toxicology and Applied Pharmacology. 100: 119-31. PMID 2763295 DOI: 10.1016/0041-008X(89)90096-3  0.392
1989 Brewster DW, Birnbaum LS. The biochemical toxicity of perfluorodecanoic acid in the mouse is different from that of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology and Applied Pharmacology. 99: 544-54. PMID 2749739 DOI: 10.1016/0041-008X(89)90161-0  0.315
1989 Sabourin PJ, Bechtold WE, Griffith WC, Birnbaum LS, Lucier G, Henderson RF. Effect of exposure concentration, exposure rate, and route of administration on metabolism of benzene by F344 rats and B6C3F1 mice. Toxicology and Applied Pharmacology. 99: 421-44. PMID 2749731 DOI: 10.1016/0041-008X(89)90151-8  0.327
1989 Gerlach RF, Medinsky MA, Hobbs CH, Bice DE, Bechtold WE, Cheng YS, Gillett NA, Birnbaum LS, Mauderly JL. Effect of four-week repeated inhalation exposure to unconjugated azodicarbonamide on specific and non-specific airway sensitivity of the guinea pig. Journal of Applied Toxicology : Jat. 9: 145-53. PMID 2745922 DOI: 10.1002/Jat.2550090303  0.356
1989 Harris MW, Uraih LC, Birnbaum LS. Acute toxicity of perfluorodecanoic acid in C57BL/6 mice differs from 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 13: 723-36. PMID 2620793 DOI: 10.1016/0272-0590(89)90330-8  0.308
1988 Couture LA, Elwell MR, Birnbaum LS. Dioxin-like effects observed in male rats following exposure to octachlorodibenzo-p-dioxin (OCDD) during a 13-week study. Toxicology and Applied Pharmacology. 93: 31-46. PMID 3354000 DOI: 10.1016/0041-008X(88)90023-3  0.357
1988 Birnbaum LS, Couture LA. Disposition of octachlorodibenzo-p-dioxin (OCDD) in male rats Toxicology and Applied Pharmacology. 93: 22-30. PMID 3353999 DOI: 10.1016/0041-008X(88)90022-1  0.319
1987 Birnbaum LS, Harris MW, Crawford DD, Morrissey RE. Teratogenic effects of polychlorinated dibenzofurans in combination in C57BL/6N mice. Toxicology and Applied Pharmacology. 91: 246-55. PMID 3672524 DOI: 10.1016/0041-008X(87)90105-0  0.308
1987 Brewster DW, Birnbaum LS. Disposition and excretion of 2,3,4,7,8-pentachlorodibenzofuran in the rat Toxicology and Applied Pharmacology. 90: 243-252. PMID 3629600 DOI: 10.1016/0041-008X(87)90332-2  0.312
1985 Birnbaum LS. The role of structure in the disposition of halogenated aromatic xenobiotics Environmental Health Perspectives. 11-20. PMID 2998745 DOI: 10.1289/Ehp.856111  0.337
1980 Birnbaum LS. Altered hepatic drug metabolism in senescent mice Experimental Gerontology. 15: 259-267. PMID 6773794 DOI: 10.1016/0531-5565(80)90030-3  0.318
1979 Birnbaum LS, Baird MB. Senescent changes in rodent hepatic epoxide metabolism Chemico-Biological Interactions. 26: 245-256. PMID 509688 DOI: 10.1016/0009-2797(79)90028-0  0.34
1978 Birnbaum LS, Baird MB. Induction of hepatic mixed function oxidases in senescent rodents-II. Effect of polychlorinated biphenyls Experimental Gerontology. 13: 469-477. PMID 104883 DOI: 10.1016/0531-5565(78)90059-1  0.313
Show low-probability matches.