Charles L. Sentman - Publications

Affiliations: 
Immunology and Microbiology Dartmouth College, Hanover, NH, United States 
Area:
Cell Biology, Molecular Biology

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Meister H, Look T, Roth P, Pascolo S, Sahin U, Lee S, Hale BD, Snijder B, Regli L, Ravi V, Heiland DH, Sentman CL, Weller M, Weiss T. Multifunctional mRNA-based CAR T cells display promising anti-tumor activity against glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36037304 DOI: 10.1158/1078-0432.CCR-21-4384  0.468
2022 Brog RA, Ferry SL, Schiebout CT, Messier CM, Cook WJ, Abdullah L, Zou J, Kumar P, Sentman CL, Frost HR, Huang YH. Superkine IL2 and IL33 armored CAR T cells reshape the tumor microenvironment and reduce growth of multiple solid tumors. Cancer Immunology Research. PMID 35696724 DOI: 10.1158/2326-6066.CIR-21-0536  0.497
2021 Butler SE, Brog RA, Chang CH, Sentman CL, Huang YH, Ackerman ME. Engineering a natural ligand-based CAR: directed evolution of the stress-receptor NKp30. Cancer Immunology, Immunotherapy : Cii. PMID 34046711 DOI: 10.1007/s00262-021-02971-y  0.439
2020 Cook WJ, Choi Y, Gacerez A, Bailey-Kellogg C, Sentman CL. A Chimeric Antigen Receptor That Binds to a Conserved Site on MICA. Immunohorizons. 4: 597-607. PMID 33037097 DOI: 10.4049/immunohorizons.2000041  0.462
2020 Godbersen-Palmer C, Coupet TA, Grada Z, Zhang SC, Sentman CL. Toxicity Induced by a Bispecific T Cell-Redirecting Protein Is Mediated by Both T Cells and Myeloid Cells in Immunocompetent Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 32295875 DOI: 10.4049/jimmunol.1901401  0.473
2019 Godbersen-Palmer C, Coupet T, Grada Z, Sentman C. Abstract 1542: Bispecific T cell engager-induced toxicity in an immunocompetent solid tumor model Cancer Research. 79: 1542-1542. DOI: 10.1158/1538-7445.Am2019-1542  0.574
2019 Coupet TA, Godbersen-Palmer C, Sentman CL. Abstract 1539: Mechanisms of action of bispecific T cell engager-mediated immune response in a lymphoma tumor model Cancer Research. 79: 1539-1539. DOI: 10.1158/1538-7445.Am2019-1539  0.558
2019 Weiss T, Meister H, Weller M, Sentman C, Roth P. IMMU-17. TARGETING GLIOBLASTOMA WITH DNAM-1-BASED CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS Neuro-Oncology. 21: vi122-vi122. DOI: 10.1093/Neuonc/Noz175.510  0.602
2019 Weiss T, Meister H, Weller M, Sentman C, Roth P. PL2.1 Exploiting the DNAM-1 system for chimeric antigen receptor (CAR) T cell therapy of glioblastoma Neuro-Oncology. 21: iii2-iii2. DOI: 10.1093/Neuonc/Noz126.002  0.615
2018 Baumeister SH, Murad J, Werner L, Daley H, Trebeden-Negre H, Gicobi JK, Schmucker A, Reder J, Sentman CL, Gilham DE, Lehmann FF, Galinsky I, DiPietro H, Cummings K, Munshi NC, et al. Phase 1 Trial of Autologous CAR T Cells Targeting NKG2D Ligands in Patients with AML/MDS and Multiple Myeloma. Cancer Immunology Research. PMID 30396908 DOI: 10.1158/2326-6066.Cir-18-0307  0.483
2018 Murad JM, Baumeister SH, Werner L, Daley H, Trébéden-Negre H, Reder J, Sentman CL, Gilham D, Lehmann F, Snykers S, Sentman ML, Wade T, Schmucker A, Fanger MW, Dranoff G, et al. Manufacturing development and clinical production of NKG2D chimeric antigen receptor-expressing T cells for autologous adoptive cell therapy. Cytotherapy. 20: 952-963. PMID 30180944 DOI: 10.1016/J.Jcyt.2018.05.001  0.487
2018 Murad JM, Graber DJ, Sentman CL. Advances in the use of natural receptor- or ligand-based chimeric antigen receptors (CARs) in haematologic malignancies. Best Practice & Research. Clinical Haematology. 31: 176-183. PMID 29909918 DOI: 10.1016/j.beha.2018.03.003  0.39
2018 Gacerez AT, Sentman CL. T-bet promotes potent antitumor activity of CD4CAR T cells. Cancer Gene Therapy. PMID 29515240 DOI: 10.1038/S41417-018-0012-7  0.622
2018 Gacerez AT, Hua CK, Ackerman ME, Sentman CL. Chimeric antigen receptors with human scFvs preferentially induce T cell anti-tumor activity against tumors with high B7H6 expression. Cancer Immunology, Immunotherapy : Cii. PMID 29453518 DOI: 10.1007/s00262-018-2124-1  0.466
2017 Weiss T, Weller M, Guckenberger M, Sentman CL, Roth P. NKG2D-based CAR-T cells and radiotherapy exert synergistic efficacy in glioblastoma. Cancer Research. PMID 29222400 DOI: 10.1158/0008-5472.Can-17-1788  0.609
2017 Hua CK, Gacerez AT, Sentman CL, Ackerman ME. Development of unique cytotoxic chimeric antigen receptors based on human scFv targeting B7H6. Protein Engineering, Design & Selection : Peds. 1-9. PMID 29040754 DOI: 10.1093/protein/gzx051  0.504
2017 Demoulin B, Cook WJ, Murad J, Graber DJ, Sentman ML, Lonez C, Gilham DE, Sentman CL, Agaugue S. Exploiting natural killer group 2D receptors for CAR T-cell therapy. Future Oncology (London, England). PMID 28613086 DOI: 10.2217/fon-2017-0102  0.477
2017 Godbersen C, Coupet TA, Huehls AM, Zhang T, Battles MB, Fisher JL, Ernstoff MS, Sentman CL. NKG2D ligand targeted Bispecific T Cell Engagers lead to robust antitumor activity against diverse human tumors. Molecular Cancer Therapeutics. PMID 28500232 DOI: 10.1158/1535-7163.MCT-16-0846  0.552
2017 Weiss T, Weller M, Pruschy M, Sentman C, Roth P. OS09.3 Synergistic activity of NKG2D-based chimeric antigen receptor (CAR)-T cells and radiotherapy against glioma Neuro-Oncology. 19: iii18-iii18. DOI: 10.1093/Neuonc/Nox036.062  0.52
2017 Sentman CL. Preclinical Studies in CAR T Cell Development Clinical Lymphoma Myeloma and Leukemia. 17: S205-S207. DOI: 10.1016/j.clml.2017.08.092  0.401
2016 Sentman ML, Murad JM, Cook WJ, Wu MR, Reder J, Baumeister SH, Dranoff G, Fanger MW, Sentman CL. Mechanisms of Acute Toxicity in NKG2D Chimeric Antigen Receptor T Cell-Treated Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 27849169 DOI: 10.4049/Jimmunol.1600769  0.849
2016 Arellano B, Graber DJ, Sentman CL. Regulatory T cell-based therapies for autoimmunity. Discovery Medicine. 22: 73-80. PMID 27585233  0.375
2016 Smits NC, Coupet TA, Godbersen C, Sentman CL. Designing multivalent proteins based on natural killer cell receptors and their ligands as immunotherapy for cancer. Expert Opinion On Biological Therapy. PMID 27248342 DOI: 10.1080/14712598.2016.1195364  0.55
2016 Rajasekaran K, Riese MJ, Rao S, Wang L, Thakar MS, Sentman CL, Malarkannan S. Signaling in Effector Lymphocytes: Insights toward Safer Immunotherapy. Frontiers in Immunology. 7: 176. PMID 27242783 DOI: 10.3389/Fimmu.2016.00176  0.409
2016 Gacerez AT, Arellano B, Sentman CL. How Chimeric Antigen Receptor Design Affects Adoptive T Cell Therapy. Journal of Cellular Physiology. PMID 27163336 DOI: 10.1002/Jcp.25419  0.553
2016 Smits NC, Sentman CL. Bispecific T-Cell Engagers (BiTEs) as Treatment of B-Cell Lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26884583 DOI: 10.1200/Jco.2015.64.9970  0.49
2016 Nikiforow S, Murad J, Daley H, Negre H, Reder J, Sentman CL, Lehmann F, Snykers S, Allen R, Galinsky I, Munshi NC, Stone RM, Soiffer R, Ritz J, Baumeister SH. A first-in-human phase I trial of NKG2D chimeric antigen receptor-T cells in AML/MDS and multiple myeloma. Journal of Clinical Oncology. 34: TPS3102-TPS3102. DOI: 10.1200/Jco.2016.34.15_Suppl.Tps3102  0.596
2016 Nikiforow S, Werner L, Murad J, Jacobs M, Johnston L, Patches S, White R, Daley H, Negre H, Reder J, Sentman C, Wade T, Schmucker A, Lehmann FF, Snykers S, et al. Safety Data from a First-in-Human Phase 1 Trial of NKG2D Chimeric Antigen Receptor-T Cells in AML/MDS and Multiple Myeloma Blood. 128: 4052-4052. DOI: 10.1182/Blood.V128.22.4052.4052  0.525
2016 Daley H, Nikiforow S, Murad J, Negre H, Reider J, Sentman C, Snykers S, Allen R, Galinsky I, Munshi N, Stone R, Soiffer R, Ritz J, Baumeister S. 71. Validation of Manufacturing NKG2D Chimeric Antigen Receptor T Cells for a First-In-Human Clinical Trial in AML/MDS and Multiple Myeloma Molecular Therapy. 24: S31. DOI: 10.1016/S1525-0016(16)32880-5  0.62
2015 Gowen BG, Chim B, Marceau CD, Greene TT, Burr P, Gonzalez JR, Hesser CR, Dietzen PA, Russell T, Iannello A, Coscoy L, Sentman CL, Carette JE, Muljo SA, Raulet DH. A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells. Elife. 4. PMID 26565589 DOI: 10.7554/Elife.08474  0.565
2015 Choi Y, Hua C, Sentman CL, Ackerman ME, Bailey-Kellogg C. Antibody humanization by structure-based computational protein design. Mabs. 7: 1045-57. PMID 26252731 DOI: 10.1080/19420862.2015.1076600  0.303
2015 Wu MR, Zhang T, Gacerez AT, Coupet TA, DeMars LR, Sentman CL. B7H6-Specific Bispecific T Cell Engagers Lead to Tumor Elimination and Host Antitumor Immunity. Journal of Immunology (Baltimore, Md. : 1950). 194: 5305-11. PMID 25911747 DOI: 10.4049/Jimmunol.1402517  0.857
2015 Wu MR, Zhang T, DeMars LR, Sentman CL. B7H6-specific chimeric antigen receptors lead to tumor elimination and host antitumor immunity. Gene Therapy. PMID 25830550 DOI: 10.1038/Gt.2015.29  0.841
2015 Wu MR, Zhang T, Alcon A, Sentman CL. DNAM-1-based chimeric antigen receptors enhance T cell effector function and exhibit in vivo efficacy against melanoma. Cancer Immunology, Immunotherapy : Cii. 64: 409-18. PMID 25549845 DOI: 10.1007/S00262-014-1648-2  0.838
2015 Stephan SB, Taber AM, Jileaeva I, Pegues EP, Sentman CL, Stephan MT. Biopolymer implants enhance the efficacy of adoptive T-cell therapy. Nature Biotechnology. 33: 97-101. PMID 25503382 DOI: 10.1038/Nbt.3104  0.532
2015 Huehls AM, Coupet TA, Sentman CL. Bispecific T-cell engagers for cancer immunotherapy. Immunology and Cell Biology. 93: 290-6. PMID 25367186 DOI: 10.1038/Icb.2014.93  0.598
2015 Gowen BG, Chim B, Marceau CD, Greene TT, Burr P, Gonzalez JR, Hesser CR, Dietzen PA, Russell T, Iannello A, Coscoy L, Sentman CL, Carette JE, Muljo SA, Raulet DH. Author response: A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells Elife. DOI: 10.7554/Elife.08474.033  0.366
2014 Wu MR, Cook WJ, Zhang T, Sentman CL. Targeting multiple types of tumors using NKG2D-coated iron oxide nanoparticles. Nanotechnology. 25: 475101. PMID 25371538 DOI: 10.1088/0957-4484/25/47/475101  0.802
2014 Sentman CL, Meehan KR. NKG2D CARs as cell therapy for cancer. Cancer Journal (Sudbury, Mass.). 20: 156-9. PMID 24667963 DOI: 10.1097/Ppo.0000000000000029  0.61
2014 Talebian L, Fischer DA, Wu J, Channon JY, Sentman CL, Ernstoff MS, Meehan KR. The natural killer-activating receptor, NKG2D, on CD3+CD8+ T cells plays a critical role in identifying and killing autologous myeloma cells. Transfusion. 54: 1515-21. PMID 24446786 DOI: 10.1111/Trf.12517  0.523
2014 Spear P, Barber A, Rynda-Apple A, Sentman CL. Correction: Chimeric Antigen Receptor T Cells Shape Myeloid Cell Function within the Tumor Microenvironment through IFN-γ and GM-CSF The Journal of Immunology. 193: 1513.4-1513. DOI: 10.4049/jimmunol.1490025c  0.856
2014 Barber A, Rynda A, Sentman CL. Correction: Chimeric NKG2D Expressing T Cells Eliminate Immunosuppression and Activate Immunity within the Ovarian Tumor Microenvironment The Journal of Immunology. 193: 1513.3-1513. DOI: 10.4049/jimmunol.1490025b  0.815
2013 Sentman CL. Challenges of creating effective chimeric antigen receptors for cancer therapy. Immunotherapy. 5: 783-5. PMID 23902543 DOI: 10.2217/Imt.13.71  0.547
2013 Spear P, Wu MR, Sentman ML, Sentman CL. NKG2D ligands as therapeutic targets. Cancer Immunity. 13: 8. PMID 23833565  0.796
2013 Spear P, Barber A, Sentman CL. Collaboration of chimeric antigen receptor (CAR)-expressing T cells and host T cells for optimal elimination of established ovarian tumors. Oncoimmunology. 2: e23564. PMID 23734311 DOI: 10.4161/Onci.23564  0.86
2013 Spear P, Barber A, Rynda-Apple A, Sentman CL. NKG2D CAR T-cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors. Immunology and Cell Biology. 91: 435-40. PMID 23628805 DOI: 10.1038/Icb.2013.17  0.854
2013 Zhang T, Sentman CL. Mouse tumor vasculature expresses NKG2D ligands and can be targeted by chimeric NKG2D-modified T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 2455-63. PMID 23355740 DOI: 10.4049/Jimmunol.1201314  0.612
2013 Meehan KR, Talebian L, Tosteson TD, Hill JM, Szczepiorkowski Z, Sentman CL, Ernstoff MS. Adoptive cellular therapy using cells enriched for NKG2D+CD3+CD8+T cells after autologous transplantation for myeloma. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 129-37. PMID 22975165 DOI: 10.1016/J.Bbmt.2012.08.018  0.45
2012 Zhang T, Wu MR, Sentman CL. An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo. Journal of Immunology (Baltimore, Md. : 1950). 189: 2290-9. PMID 22851709 DOI: 10.4049/Jimmunol.1103495  0.85
2012 Spear P, Barber A, Rynda-Apple A, Sentman CL. Chimeric antigen receptor T cells shape myeloid cell function within the tumor microenvironment through IFN-γ and GM-CSF. Journal of Immunology (Baltimore, Md. : 1950). 188: 6389-98. PMID 22586039 DOI: 10.4049/Jimmunol.1103019  0.865
2011 Iyori M, Zhang T, Pantel H, Gagne BA, Sentman CL. TRAIL/DR5 plays a critical role in NK cell-mediated negative regulation of dendritic cell cross-priming of T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 3087-95. PMID 21832159 DOI: 10.4049/Jimmunol.1003879  0.572
2011 Talebian L, Wu JY, Fischer DA, Hill JM, Szczepiorkowski ZM, Ernstoff MS, Sentman CL, Meehan KR. Novel mobilization strategies to enhance autologous immune effector cells in multiple myeloma. Frontiers in Bioscience (Elite Edition). 3: 1500-8. PMID 21622154 DOI: 10.2741/E351  0.497
2011 Barber A, Sentman CL. NKG2D receptor regulates human effector T-cell cytokine production. Blood. 117: 6571-81. PMID 21518928 DOI: 10.1182/Blood-2011-01-329417  0.792
2011 Zhang T, Sentman CL. Cancer immunotherapy using a bispecific NK receptor fusion protein that engages both T cells and tumor cells. Cancer Research. 71: 2066-76. PMID 21282338 DOI: 10.1158/0008-5472.Can-10-3200  0.674
2011 Barber A, Meehan KR, Sentman CL. Treatment of multiple myeloma with adoptively transferred chimeric NKG2D receptor-expressing T cells. Gene Therapy. 18: 509-16. PMID 21209626 DOI: 10.1038/Gt.2010.174  0.825
2010 Meehan KR, Talebian L, Wu J, Hill JM, Szczepiorkowski ZM, Sentman CL, Ernstoff MS. Immune mobilization of autologous blood progenitor cells: direct influence on the cellular subsets collected. Cytotherapy. 12: 1013-21. PMID 20873991 DOI: 10.3109/14653249.2010.515580  0.485
2010 Kopcow HD, Eriksson M, Mselle TF, Damrauer SM, Wira CR, Sentman CL, Strominger JL. Human decidual NK cells from gravid uteri and NK cells from cycling endometrium are distinct NK cell subsets. Placenta. 31: 334-8. PMID 20172608 DOI: 10.1016/J.Placenta.2010.01.003  0.81
2010 Talebian L, Meehan K, Patey ME, Fisher DA, Szczepiorkowski Z, Ernstoff M, Sentman C. NKG2D, An NK Cell Activating Receptor on CD8+ T Cells, Plays An Essential Role In Killing Myeloma Cells Blood. 116: 2087-2087. DOI: 10.1182/Blood.V116.21.2087.2087  0.513
2009 Barber A, Rynda A, Sentman CL. Chimeric NKG2D expressing T cells eliminate immunosuppression and activate immunity within the ovarian tumor microenvironment. Journal of Immunology (Baltimore, Md. : 1950). 183: 6939-47. PMID 19915047 DOI: 10.4049/Jimmunol.0902000  0.846
2009 Mselle TF, Howell AL, Ghosh M, Wira CR, Sentman CL. Human uterine natural killer cells but not blood natural killer cells inhibit human immunodeficiency virus type 1 infection by secretion of CXCL12. Journal of Virology. 83: 11188-95. PMID 19692460 DOI: 10.1128/Jvi.00562-09  0.765
2009 Barber A, Sentman CL. Chimeric NKG2D T cells require both T cell- and host-derived cytokine secretion and perforin expression to increase tumor antigen presentation and systemic immunity. Journal of Immunology (Baltimore, Md. : 1950). 183: 2365-72. PMID 19625653 DOI: 10.4049/Jimmunol.0900721  0.839
2009 Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR. Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. The Journal of Clinical Investigation. 119: 2231-44. PMID 19620771 DOI: 10.1172/Jci37716  0.791
2009 Kalkunte SS, Mselle TF, Norris WE, Wira CR, Sentman CL, Sharma S. Vascular endothelial growth factor C facilitates immune tolerance and endovascular activity of human uterine NK cells at the maternal-fetal interface. Journal of Immunology (Baltimore, Md. : 1950). 182: 4085-92. PMID 19299706 DOI: 10.4049/Jimmunol.0803769  0.779
2009 Basu S, Eriksson M, Pioli PA, Conejo-Garcia J, Mselle TF, Yamamoto S, Wira CR, Sentman CL. Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 61: 52-61. PMID 19086992 DOI: 10.1111/J.1600-0897.2008.00661.X  0.784
2009 Talebian LX, Fischer DA, Szczepiorkowski ZM, Sentman CL, Meehan KR. The Critical Requirement of the NKG2D Receptor On CD8+ T Cells in Killing Myeloma Cells. Blood. 114: 4733-4733. DOI: 10.1182/Blood.V114.22.4733.4733  0.601
2009 Kakarla S, Shaffer D, Ahmed N, Wang L, Lee D, Sentman C, Gottschalk S. T-Cells Redirected Against NKG2D-Ligands for the Immunotherapy of Osteosarcoma Biology of Blood and Marrow Transplantation. 15: 82-83. DOI: 10.1016/J.Bbmt.2008.12.255  0.522
2008 Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Buckanovich RJ, Benencia F, Stan RV, Keler T, Sarobe P, Sentman CL, Conejo-Garcia JR. Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity. Cancer Research. 68: 7684-91. PMID 18768667 DOI: 10.1158/0008-5472.Can-08-1167  0.465
2008 Basu S, Pioli PA, Conejo-Garcia J, Wira CR, Sentman CL. Estradiol regulates MICA expression in human endometrial cells. Clinical Immunology (Orlando, Fla.). 129: 325-32. PMID 18728002 DOI: 10.1016/J.Clim.2008.07.005  0.799
2008 Barber A, Zhang T, Megli CJ, Wu J, Meehan KR, Sentman CL. Chimeric NKG2D receptor-expressing T cells as an immunotherapy for multiple myeloma. Experimental Hematology. 36: 1318-28. PMID 18599182 DOI: 10.1016/J.Exphem.2008.04.010  0.838
2008 Kalkunte S, Chichester CO, Gotsch F, Sentman CL, Romero R, Sharma S. Evolution of non-cytotoxic uterine natural killer cells. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 59: 425-32. PMID 18405313 DOI: 10.1111/J.1600-0897.2008.00595.X  0.517
2008 Meehan KR, Wu J, Webber SM, Barber A, Szczepiorkowski ZM, Sentman C. Development of a clinical model for ex vivo expansion of multiple populations of effector cells for adoptive cellular therapy. Cytotherapy. 10: 30-7. PMID 18202972 DOI: 10.1080/14653240701762398  0.781
2008 Barber A, Zhang T, Sentman CL. Immunotherapy with chimeric NKG2D receptors leads to long-term tumor-free survival and development of host antitumor immunity in murine ovarian cancer. Journal of Immunology (Baltimore, Md. : 1950). 180: 72-8. PMID 18097006 DOI: 10.4049/Jimmunol.180.1.72  0.826
2008 Barber MA, Zhang T, Gagne BA, Van Ginderachter JA, De Baetselier P, Sentman CL. Ly49G2 receptor blockade reduces tumor burden in a leukemia model but not in a solid tumor model. Cancer Immunology, Immunotherapy : Cii. 57: 655-62. PMID 17891395 DOI: 10.1007/S00262-007-0404-2  0.544
2008 Meehan KR, Hill JM, Ernstoff M, Sentman CL. Immune Mobilization with IL-2 and Growth Factors: Differential in Vivo Effects of the NKG2D Receptor on CD8+ and CD56+ Effector Cells Blood. 112: 3491-3491. DOI: 10.1182/Blood.V112.11.3491.3491  0.482
2007 Zhang T, Barber A, Sentman CL. Chimeric NKG2D modified T cells inhibit systemic T-cell lymphoma growth in a manner involving multiple cytokines and cytotoxic pathways. Cancer Research. 67: 11029-36. PMID 18006849 DOI: 10.1158/0008-5472.Can-07-2251  0.835
2007 Mselle TF, Meadows SK, Eriksson M, Smith JM, Shen L, Wira CR, Sentman CL. Unique characteristics of NK cells throughout the human female reproductive tract. Clinical Immunology (Orlando, Fla.). 124: 69-76. PMID 17524808 DOI: 10.1016/J.Clim.2007.04.008  0.808
2007 Barber A, Zhang T, DeMars LR, Conejo-Garcia J, Roby KF, Sentman CL. Chimeric NKG2D receptor-bearing T cells as immunotherapy for ovarian cancer. Cancer Research. 67: 5003-8. PMID 17510432 DOI: 10.1158/0008-5472.Can-06-4047  0.828
2007 Barber MA, Zhang T, Gagne BA, Sentman CL. NK cells negatively regulate antigen presentation and tumor-specific CTLs in a syngeneic lymphoma model. Journal of Immunology (Baltimore, Md. : 1950). 178: 6140-7. PMID 17475840 DOI: 10.4049/Jimmunol.178.10.6140  0.623
2007 Sentman CL, Wira CR, Eriksson M. NK cell function in the human female reproductive tract. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 57: 108-15. PMID 17217364 DOI: 10.1111/J.1600-0897.2006.00448.X  0.51
2007 Grundy MA, Zhang T, Sentman CL. NK cells rapidly remove B16F10 tumor cells in a perforin and interferon-gamma independent manner in vivo. Cancer Immunology, Immunotherapy : Cii. 56: 1153-61. PMID 17160409 DOI: 10.1007/S00262-006-0264-1  0.572
2007 Hill JM, Wu J, Webber SM, Root LD, Kimtis EA, Williams IC, Ernstoff MS, Szczepiorkowski ZM, Sentman CL, Meehan KR. Immune Mobilization with Direct In-Vivo Effector Response: Clinical Trial with Favorable Implications for Post-Transplant Outcome. Blood. 110: 5120-5120. DOI: 10.1182/Blood.V110.11.5120.5120  0.368
2006 Eriksson M, Meadows SK, Wira CR, Sentman CL. Endogenous transforming growth factor-beta inhibits toll-like receptor mediated activation of human uterine natural killer cells. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 56: 321-8. PMID 17076676 DOI: 10.1111/J.1600-0897.2006.00432.X  0.425
2006 Grundy MA, Sentman CL. Immunodeficient mice have elevated numbers of NK cells in non-lymphoid tissues. Experimental Cell Research. 312: 3920-6. PMID 17005178 DOI: 10.1016/J.Yexcr.2006.08.019  0.546
2006 Sentman CL, Barber MA, Barber A, Zhang T. NK cell receptors as tools in cancer immunotherapy. Advances in Cancer Research. 95: 249-92. PMID 16860660 DOI: 10.1016/S0065-230X(06)95007-6  0.837
2006 Wahle JA, Paraiso KH, Costello AL, Goll EL, Sentman CL, Kerr WG. Cutting edge: dominance by an MHC-independent inhibitory receptor compromises NK killing of complex targets. Journal of Immunology (Baltimore, Md. : 1950). 176: 7165-9. PMID 16751359 DOI: 10.4049/Jimmunol.176.12.7165  0.449
2006 Zhang T, Barber A, Sentman CL. Generation of antitumor responses by genetic modification of primary human T cells with a chimeric NKG2D receptor. Cancer Research. 66: 5927-33. PMID 16740733 DOI: 10.1158/0008-5472.Can-06-0130  0.847
2006 Eriksson M, Meadows SK, Basu S, Mselle TF, Wira CR, Sentman CL. TLRs mediate IFN-gamma production by human uterine NK cells in endometrium. Journal of Immunology (Baltimore, Md. : 1950). 176: 6219-24. PMID 16670332 DOI: 10.4049/Jimmunol.176.10.6219  0.795
2006 Meadows SK, Eriksson M, Barber A, Sentman CL. Human NK cell IFN-gamma production is regulated by endogenous TGF-beta. International Immunopharmacology. 6: 1020-8. PMID 16644489 DOI: 10.1016/J.Intimp.2006.01.013  0.757
2005 Grundy M, Sentman CL. GFP transgenic mice show dynamics of lung macrophages. Experimental Cell Research. 310: 409-16. PMID 16171803 DOI: 10.1016/J.Yexcr.2005.08.007  0.356
2005 Usherwood EJ, Meadows SK, Crist SG, Bellfy SC, Sentman CL. Control of murine gammaherpesvirus infection is independent of NK cells. European Journal of Immunology. 35: 2956-61. PMID 16134085 DOI: 10.1002/Eji.200526245  0.447
2005 Wira CR, Fahey JV, Sentman CL, Pioli PA, Shen L. Innate and adaptive immunity in female genital tract: cellular responses and interactions. Immunological Reviews. 206: 306-35. PMID 16048557 DOI: 10.1111/J.0105-2896.2005.00287.X  0.429
2005 Zhang T, Lemoi BA, Sentman CL. Chimeric NK-receptor-bearing T cells mediate antitumor immunotherapy. Blood. 106: 1544-51. PMID 15890688 DOI: 10.1182/Blood-2004-11-4365  0.684
2004 Sentman CL, Meadows SK, Wira CR, Eriksson M. Recruitment of uterine NK cells: induction of CXC chemokine ligands 10 and 11 in human endometrium by estradiol and progesterone. Journal of Immunology (Baltimore, Md. : 1950). 173: 6760-6. PMID 15557169 DOI: 10.4049/Jimmunol.173.11.6760  0.551
2004 Eriksson M, Meadows SK, Wira CR, Sentman CL. Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta. Journal of Leukocyte Biology. 76: 667-75. PMID 15178706 DOI: 10.1189/Jlb.0204090  0.501
2001 Sjöström A, Eriksson M, Cerboni C, Johansson MH, Sentman CL, Kärre K, Höglund P. Acquisition of external major histocompatibility complex class I molecules by natural killer cells expressing inhibitory Ly49 receptors. The Journal of Experimental Medicine. 194: 1519-30. PMID 11714758 DOI: 10.1084/jem.194.10.1519  0.431
2001 Fahlén L, Lendahl U, Sentman CL. MHC class I-Ly49 interactions shape the Ly49 repertoire on murine NK cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 6585-92. PMID 11359811 DOI: 10.4049/jimmunol.166.11.6585  0.383
2001 Kambayashi T, Michaëlsson J, Fahlén L, Chambers BJ, Sentman CL, Kärre K, Ljunggren HG. Purified MHC class I molecules inhibit activated NK cells in a cell-free system in vitro. European Journal of Immunology. 31: 869-75. PMID 11241292 DOI: 10.1002/1521-4141(200103)31:3<869::Aid-Immu869>3.0.Co;2-A  0.357
2000 Oberg L, Eriksson M, Fahlén L, Sentman CL. Expression of Ly49A on T cells alters the threshold for T cell responses. European Journal of Immunology. 30: 2849-56. PMID 11069066 DOI: 10.1002/1521-4141(200010)30:10<2849::AID-IMMU2849>3.0.CO;2-6  0.445
2000 Fahlén L, Oberg L, Brännström T, Khoo NK, Lendahl U, Sentman CL. Ly49A expression on T cells alters T cell selection. International Immunology. 12: 215-22. PMID 10653857 DOI: 10.1093/intimm/12.2.215  0.497
2000 Eriksson M, Ryan JC, Nakamura MC, Sentman CL. Ly49A inhibitory receptors redistribute on natural killer cells during target cell interaction. Immunology. 97: 341-7. PMID 10447751 DOI: 10.1046/j.1365-2567.1999.00800.x  0.485
1999 Eriksson M, Leitz G, Fällman E, Axner O, Ryan JC, Nakamura MC, Sentman CL. Inhibitory receptors alter natural killer cell interactions with target cells yet allow simultaneous killing of susceptible targets. The Journal of Experimental Medicine. 190: 1005-12. PMID 10510090 DOI: 10.1084/jem.190.7.1005  0.387
1998 Khoo NKS, Fahlén L, Sentman CL. Modulation of Ly49A receptors on mature cells to changes in major histocompatibility complex class I molecules Immunology. 95: 126-131. PMID 9767467 DOI: 10.1046/j.1365-2567.1998.00577.x  0.451
1998 Cilio CM, Daws MR, Malashicheva A, Sentman CL, Holmberg D. Cytotoxic T lymphocyte antigen 4 is induced in the thymus upon in vivo activation and its blockade prevents anti-CD3-mediated depletion of thymocytes. The Journal of Experimental Medicine. 188: 1239-46. PMID 9763603 DOI: 10.1084/Jem.188.7.1239  0.324
1997 Fahlén L, Khoo NKS, Daws MR, Sentman CL. Location-specific regulation of transgenic Ly49A receptors by major histocompatibility complex class I molecules European Journal of Immunology. 27: 2057-2065. PMID 9295045 DOI: 10.1002/eji.1830270833  0.479
1997 Höglund P, Sundbäck J, Olsson-Alheim MY, Johansson M, Salcedo M, Ohlén C, Ljunggren HG, Sentman CL, Kärre K. Host MHC class I gene control of NK-cell specificity in the mouse. Immunological Reviews. 155: 11-28. PMID 9059879 DOI: 10.1111/j.1600-065X.1997.tb00936.x  0.405
1996 Sentman CL, Olsson-Alheim MY, Lendahl U, Kärre K. Influence of glycosylphosphatidylinositol-linked H-2Dd molecules on target cell protection and natural killer cell specificity in transgenic mice. European Journal of Immunology. 26: 2127-32. PMID 8814257 DOI: 10.1002/eji.1830260925  0.398
1995 Olsson MY, Kärre K, Sentman CL. Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand. Proceedings of the National Academy of Sciences of the United States of America. 92: 1649-53. PMID 7878033 DOI: 10.1073/pnas.92.5.1649  0.391
1995 Sentman CL, Olsson MY, Kärre K. Missing self recognition by natural killer cells in MHC class I transgenic mice. A 'receptor calibration' model for how effector cells adapt to self. Seminars in Immunology. 7: 109-19. PMID 7579193 DOI: 10.1006/smim.1995.0015  0.323
1995 Linette G, Hess J, Sentman C, Korsmeyer S. Peripheral T-cell lymphoma in lckpr-bcl-2 transgenic mice Blood. 86: 1255-1260. DOI: 10.1182/blood.V86.4.1255.bloodjournal8641255  0.409
1992 Sentman CL, Shutter JR, Hockenbery D, Kanagawa O, Korsmeyer SJ. bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell. 67: 879-88. PMID 1835668 DOI: 10.1016/0092-8674(91)90361-2  0.324
1991 Sentman CL, Kumar V, Bennett M. Rejection of bone marrow cell allografts by natural killer cell subsets: 5E6+ cell specificity for Hh-1 determinant 2 shared by H-2d and H-2f. European Journal of Immunology. 21: 2821-8. PMID 1718761 DOI: 10.1002/eji.1830211125  0.31
1989 Sentman CL, Hackett J, Kumar V, Bennett M. Identification of a subset of murine natural killer cells that mediates rejection of Hh-1d but not Hh-1b bone marrow grafts. The Journal of Experimental Medicine. 170: 191-202. PMID 2664068 DOI: 10.1084/jem.170.1.191  0.444
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