Fidel Zavala - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Immunology, Parasitology Biology, Microbiology Biology

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sinnis P, Zavala F. Reply to Vanderberg, "Further Mechanisms and Locations in Which Antisporozoite Antibodies Neutralize Malaria Sporozoites". Mbio. 10. PMID 31506316 DOI: 10.1128/mBio.02108-19  0.48
2018 Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, ... ... Zavala F, et al. Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nature Medicine. PMID 30552419 DOI: 10.1038/s41591-018-0315-0  0.48
2018 Flores-Garcia Y, Nasir G, Hopp CS, Munoz C, Balaban AE, Zavala F, Sinnis P. Antibody-Mediated Protection against Sporozoites Begins at the Dermal Inoculation Site. Mbio. 9. PMID 30459199 DOI: 10.1128/mBio.02194-18  0.48
2018 Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Scho N A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, ... ... Zavala F, et al. A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nature Medicine. PMID 29554083 DOI: 10.1038/nm.4512  0.48
2017 Espinosa DA, Christensen D, Muñoz C, Singh S, Locke E, Andersen P, Zavala F. Robust antibody and CD8(+) T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection. Npj Vaccines. 2. PMID 28936360 DOI: 10.1038/s41541-017-0011-y  0.44
2017 Luo K, Zavala F, Gordy J, Zhang H, Markham RB. Extended protection capabilities of an immature dendritic-cell targeting malaria sporozoite vaccine. Vaccine. PMID 28342669 DOI: 10.1016/j.vaccine.2017.03.052  0.44
2017 Vijayan A, Mejías-Pérez E, Espinosa DA, Raman SC, Sorzano COS, Zavala F, Esteban M. A Prime/Boost PfCS14K/MVA-sPfCS Vaccination Protocol Generates Robust CD8 T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite Protein and Protects Mice against Malaria. Clinical and Vaccine Immunology : Cvi. 24. PMID 28298290 DOI: 10.1128/CVI.00494-16  0.44
2017 Aguiar AC, Figueiredo FJ, Neuenfeldt PD, Katsuragawa TH, Drawanz BB, Cunico W, Sinnis P, Zavala F, Krettli AU. Primaquine-thiazolidinones block malaria transmission and development of the liver exoerythrocytic forms. Malaria Journal. 16: 110. PMID 28279180 DOI: 10.1186/s12936-017-1755-6  0.48
2016 Espinosa DA, Vega-Rodriguez J, Flores-Garcia Y, Noe AR, Muñoz C, Coleman R, Bruck T, Haney K, Stevens A, Retallack D, Allen J, Vedvick TS, Fox CB, Reed SG, Howard RF, ... ... Zavala F, et al. The P. falciparum Cell-Traversal Protein for Ookinetes and Sporozoites as a Candidate for Pre-Erythrocytic and Transmission-Blocking Vaccines. Infection and Immunity. PMID 27895131 DOI: 10.1128/IAI.00498-16  0.44
2016 Espinosa DA, Radtke AJ, Zavala F. Development and Assessment of Transgenic Rodent Parasites for the Preclinical Evaluation of Malaria Vaccines. Methods in Molecular Biology (Clifton, N.J.). 1403: 583-601. PMID 27076155 DOI: 10.1007/978-1-4939-3387-7_33  0.84
2016 Cockburn IA, Zavala F. Dendritic cell function and antigen presentation in malaria. Current Opinion in Immunology. 40: 1-6. PMID 26845735 DOI: 10.1016/j.coi.2016.01.010  0.72
2015 Whitacre DC, Espinosa DA, Peters CJ, Jones JE, Tucker AE, Peterson DL, Zavala FP, Milich DR. P. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections. Plos One. 10: e0124856. PMID 25933001 DOI: 10.1371/journal.pone.0124856  0.84
2015 Radtke AJ, Tse SW, Zavala F. From the draining lymph node to the liver: the induction and effector mechanisms of malaria-specific CD8+ T cells. Seminars in Immunopathology. 37: 211-20. PMID 25917387 DOI: 10.1007/s00281-015-0479-3  0.84
2015 Espinosa DA, Gutierrez GM, Rojas-López M, Noe AR, Shi L, Tse SW, Sinnis P, Zavala F. Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies. The Journal of Infectious Diseases. PMID 25762791 DOI: 10.1093/infdis/jiv154  0.84
2015 Radtke AJ, Kastenmüller W, Espinosa DA, Gerner MY, Tse SW, Sinnis P, Germain RN, Zavala FP, Cockburn IA. Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses. Plos Pathogens. 11: e1004637. PMID 25658939 DOI: 10.1371/journal.ppat.1004637  0.84
2015 Karen KA, Deal C, Adams RJ, Nielsen C, Ward C, Espinosa DA, Xie J, Zavala F, Ketner G. A replicating adenovirus capsid display recombinant elicits antibodies against Plasmodium falciparum sporozoites in Aotus nancymaae monkeys. Infection and Immunity. 83: 268-75. PMID 25368113 DOI: 10.1128/IAI.02626-14  0.84
2014 Noe AR, Espinosa D, Li X, Coelho-Dos-Reis JG, Funakoshi R, Giardina S, Jin H, Retallack DM, Haverstock R, Allen JR, Vedvick TS, Fox CB, Reed SG, Ayala R, Roberts B, ... ... Zavala F, et al. A full-length Plasmodium falciparum recombinant circumsporozoite protein expressed by Pseudomonas fluorescens platform as a malaria vaccine candidate. Plos One. 9: e107764. PMID 25247295 DOI: 10.1371/journal.pone.0107764  0.84
2014 Deal C, Balazs AB, Espinosa DA, Zavala F, Baltimore D, Ketner G. Vectored antibody gene delivery protects against Plasmodium falciparum sporozoite challenge in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 12528-32. PMID 25114213 DOI: 10.1073/pnas.1407362111  0.84
2014 Tse SW, Radtke AJ, Espinosa DA, Cockburn IA, Zavala F. The chemokine receptor CXCR6 is required for the maintenance of liver memory CD8⁺ T cells specific for infectious pathogens. The Journal of Infectious Diseases. 210: 1508-16. PMID 24823625 DOI: 10.1093/infdis/jiu281  0.84
2014 Luo K, Zhang H, Zavala F, Biragyn A, Espinosa DA, Markham RB. Fusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilities. Plos One. 9: e90413. PMID 24599116 DOI: 10.1371/journal.pone.0090413  0.84
2014 Sack BK, Miller JL, Vaughan AM, Douglass A, Kaushansky A, Mikolajczak S, Coppi A, Gonzalez-Aseguinolaza G, Tsuji M, Zavala F, Sinnis P, Kappe SH. Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum. Infection and Immunity. 82: 808-17. PMID 24478094 DOI: 10.1128/IAI.01249-13  0.84
2014 Cockburn IA, Tse SW, Zavala F. CD8+ T cells eliminate liver-stage Plasmodium berghei parasites without detectable bystander effect. Infection and Immunity. 82: 1460-4. PMID 24421043 DOI: 10.1128/IAI.01500-13  0.84
2013 Espinosa DA, Yadava A, Angov E, Maurizio PL, Ockenhouse CF, Zavala F. Development of a chimeric Plasmodium berghei strain expressing the repeat region of the P. vivax circumsporozoite protein for in vivo evaluation of vaccine efficacy. Infection and Immunity. 81: 2882-7. PMID 23716612 DOI: 10.1128/IAI.00461-13  0.44
2013 Cockburn IA, Amino R, Kelemen RK, Kuo SC, Tse SW, Radtke A, Mac-Daniel L, Ganusov VV, Zavala F, Ménard R. In vivo imaging of CD8+ T cell-mediated elimination of malaria liver stages. Proceedings of the National Academy of Sciences of the United States of America. 110: 9090-5. PMID 23674673 DOI: 10.1073/pnas.1303858110  0.84
2013 Tse SW, Cockburn IA, Zhang H, Scott AL, Zavala F. Unique transcriptional profile of liver-resident memory CD8+ T cells induced by immunization with malaria sporozoites. Genes and Immunity. 14: 302-9. PMID 23594961 DOI: 10.1038/gene.2013.20  0.84
2013 Kastenmüller K, Espinosa DA, Trager L, Stoyanov C, Salazar AM, Pokalwar S, Singh S, Dutta S, Ockenhouse CF, Zavala F, Seder RA. Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice. Infection and Immunity. 81: 789-800. PMID 23275094 DOI: 10.1128/IAI.01108-12  0.84
2013 Chen YC, Zavala F. Development and use of TCR transgenic mice for malaria immunology research. Methods in Molecular Biology (Clifton, N.J.). 923: 481-91. PMID 22990799 DOI: 10.1007/978-1-62703-026-7_33  0.72
2012 Sinnis P, Zavala F. The skin: where malaria infection and the host immune response begin. Seminars in Immunopathology. 34: 787-92. PMID 23053392 DOI: 10.1007/s00281-012-0345-5  0.84
2012 Vijayan A, Gómez CE, Espinosa DA, Goodman AG, Sanchez-Sampedro L, Sorzano CO, Zavala F, Esteban M. Adjuvant-like effect of vaccinia virus 14K protein: a case study with malaria vaccine based on the circumsporozoite protein. Journal of Immunology (Baltimore, Md. : 1950). 188: 6407-17. PMID 22615208 DOI: 10.4049/jimmunol.1102492  0.44
2011 Tse SW, Radtke AJ, Zavala F. Induction and maintenance of protective CD8+ T cells against malaria liver stages: implications for vaccine development. MemóRias Do Instituto Oswaldo Cruz. 106: 172-8. PMID 21881772  0.84
2011 Cockburn IA, Tse SW, Radtke AJ, Srinivasan P, Chen YC, Sinnis P, Zavala F. Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo. Plos Pathogens. 7: e1001318. PMID 21445239 DOI: 10.1371/journal.ppat.1001318  0.84
2011 Overstreet MG, Chen YC, Cockburn IA, Tse SW, Zavala F. CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites. Plos One. 6: e15948. PMID 21245909 DOI: 10.1371/journal.pone.0015948  0.84
2011 Palma C, Overstreet MG, Guedon JM, Hoiczyk E, Ward C, Karen KA, Zavala F, Ketner G. Adenovirus particles that display the Plasmodium falciparum circumsporozoite protein NANP repeat induce sporozoite-neutralizing antibodies in mice. Vaccine. 29: 1683-9. PMID 21199707 DOI: 10.1016/j.vaccine.2010.12.040  0.84
2010 Cockburn IA, Chen YC, Overstreet MG, Lees JR, van Rooijen N, Farber DL, Zavala F. Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites. Plos Pathogens. 6: e1000877. PMID 20463809 DOI: 10.1371/journal.ppat.1000877  0.84
2010 Riley EM, Couper KN, Helmby H, Hafalla JC, de Souza JB, Langhorne J, Jarra WB, Zavala F. Neuropathogenesis of human and murine malaria. Trends in Parasitology. 26: 277-8. PMID 20338809 DOI: 10.1016/j.pt.2010.03.002  0.84
2010 Noland GS, Chowdhury DR, Urban JF, Zavala F, Kumar N. Helminth infection impairs the immunogenicity of a Plasmodium falciparum DNA vaccine, but not irradiated sporozoites, in mice. Vaccine. 28: 2917-23. PMID 20188676 DOI: 10.1016/j.vaccine.2010.02.055  0.84
2010 Overstreet MG, Freyberger H, Cockburn IA, Chen YC, Tse SW, Zavala F. CpG-enhanced CD8+ T-cell responses to peptide immunization are severely inhibited by B cells. European Journal of Immunology. 40: 124-33. PMID 19830730 DOI: 10.1002/eji.200939493  0.84
2008 Overstreet MG, Cockburn IA, Chen YC, Zavala F. Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response. Immunological Reviews. 225: 272-83. PMID 18837788 DOI: 10.1111/j.1600-065X.2008.00671.x  0.72
2008 Dalai SK, Mirshahidi S, Morrot A, Zavala F, Sadegh-Nasseri S. Anergy in memory CD4+ T cells is induced by B cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 3221-31. PMID 18713993  0.84
2008 Srivastava K, Cockburn IA, Swaim A, Thompson LE, Tripathi A, Fletcher CA, Shirk EM, Sun H, Kowalska MA, Fox-Talbot K, Sullivan D, Zavala F, Morrell CN. Platelet factor 4 mediates inflammation in experimental cerebral malaria. Cell Host & Microbe. 4: 179-87. PMID 18692777 DOI: 10.1016/j.chom.2008.07.003  0.84
2008 Chakravarty S, Baldeviano GC, Overstreet MG, Zavala F. Effector CD8+ T lymphocytes against liver stages of Plasmodium yoelii do not require gamma interferon for antiparasite activity. Infection and Immunity. 76: 3628-31. PMID 18519561 DOI: 10.1128/IAI.00471-08  0.84
2008 Sinnis P, Zavala F. The skin stage of malaria infection: biology and relevance to the malaria vaccine effort. Future Microbiology. 3: 275-8. PMID 18505393 DOI: 10.2217/17460913.3.3.275  0.84
2008 Cockburn IA, Chakravarty S, Overstreet MG, García-Sastre A, Zavala F. Memory CD8+ T cell responses expand when antigen presentation overcomes T cell self-regulation. Journal of Immunology (Baltimore, Md. : 1950). 180: 64-71. PMID 18097005  0.72
2007 Chakravarty S, Cockburn IA, Kuk S, Overstreet MG, Sacci JB, Zavala F. CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes. Nature Medicine. 13: 1035-41. PMID 17704784 DOI: 10.1038/nm1628  0.72
2007 Melendi GA, Zavala F, Buchholz UJ, Boivin G, Collins PL, Kleeberger SR, Polack FP. Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus. Journal of Virology. 81: 11461-7. PMID 17670840 DOI: 10.1128/JVI.02423-06  0.84
2007 Cockburn IA, Zavala F. T cell memory in malaria. Current Opinion in Immunology. 19: 424-9. PMID 17624749 DOI: 10.1016/j.coi.2007.05.008  0.72
2007 Acacia de Sa Pinheiro A, Morrot A, Chakravarty S, Overstreet M, Bream JH, Irusta PM, Zavala F. IL-4 induces a wide-spectrum intracellular signaling cascade in CD8+ T cells. Journal of Leukocyte Biology. 81: 1102-10. PMID 17200144 DOI: 10.1189/jlb.0906583  0.36
2006 Morrot A, Cockburn IA, Overstreet M, Rodríguez D, Zavala F. Protective CD8+ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression. Infection and Immunity. 74: 2495-7. PMID 16552087 DOI: 10.1128/IAI.74.4.2495-2497.2006  0.72
2006 Boscardin SB, Hafalla JC, Masilamani RF, Kamphorst AO, Zebroski HA, Rai U, Morrot A, Zavala F, Steinman RM, Nussenzweig RS, Nussenzweig MC. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. The Journal of Experimental Medicine. 203: 599-606. PMID 16505139 DOI: 10.1084/jem.20051639  0.84
2005 Morrot A, Hafalla JC, Cockburn IA, Carvalho LH, Zavala F. IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites. The Journal of Experimental Medicine. 202: 551-60. PMID 16087712 DOI: 10.1084/jem.20042463  0.72
2004 del Portillo HA, Lanzer M, Rodriguez-Malaga S, Zavala F, Fernandez-Becerra C. Variant genes and the spleen in Plasmodium vivax malaria. International Journal For Parasitology. 34: 1547-54. PMID 15582531 DOI: 10.1016/j.ijpara.2004.10.012  0.84
2004 Tongren JE, Zavala F, Roos DS, Riley EM. Malaria vaccines: if at first you don't succeed... Trends in Parasitology. 20: 604-10. PMID 15522671 DOI: 10.1016/j.pt.2004.09.005  0.84
2002 Jung S, Unutmaz D, Wong P, Sano G, De los Santos K, Sparwasser T, Wu S, Vuthoori S, Ko K, Zavala F, Pamer EG, Littman DR, Lang RA. In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity. 17: 211-20. PMID 12196292 DOI: 10.1016/S1074-7613(02)00365-5  0.84
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