Fidel Zavala - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Immunology, Parasitology Biology, Microbiology Biology

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Di Pilato M, Kfuri-Rubens R, Pruessmann JN, Ozga AJ, Messemaker M, Cadilha BL, Sivakumar R, Cianciaruso C, Warner RD, Marangoni F, Carrizosa E, Lesch S, Billingsley J, Perez-Ramos D, Zavala F, et al. CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment. Cell. PMID 34343496 DOI: 10.1016/j.cell.2021.07.015  1
2021 Reeder SM, Bah MA, Tursi NJ, Brooks RC, Patel A, Esquivel R, Eaton A, Jhun H, Chu J, Kim K, Xu Z, Zavala F, Weiner DB. Strategic variants of CSP delivered as SynDNA vaccines demonstrate heterogeneity of immunogenicity and protection from infection in a murine model. Infection and Immunity. IAI0072820. PMID 34152830 DOI: 10.1128/IAI.00728-20  0.01
2021 Pholcharee T, Oyen D, Flores-Garcia Y, Gonzalez-Paez G, Han Z, Williams KL, Volkmuth W, Emerling D, Locke E, Richter King C, Zavala F, Wilson IA. Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nature Communications. 12: 1063. PMID 33594061 DOI: 10.1038/s41467-021-21221-4  1
2021 Jelínková L, Jhun H, Eaton A, Petrovsky N, Zavala F, Chackerian B. An epitope-based malaria vaccine targeting the junctional region of circumsporozoite protein. Npj Vaccines. 6: 13. PMID 33479242 DOI: 10.1038/s41541-020-00274-4  0.01
2021 Luo K, Gordy JT, Zavala F, Markham RB. A chemokine-fusion vaccine targeting immature dendritic cells elicits elevated antibody responses to malaria sporozoites in infant macaques. Scientific Reports. 11: 1220. PMID 33441615 DOI: 10.1038/s41598-020-79427-3  1
2020 Kielau Kisalu N, Da Silva Pereira L, Ernste KJ, Flores-Garcia Y, Idris AH, Asokan M, Dillon M, MacDonald S, Shi W, Chen X, Pegu A, Schön A, Zavala F, Balazs AB, Francica JR, et al. Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention. Jci Insight. PMID 33332286 DOI: 10.1172/jci.insight.143958  1
2020 Wang LT, Pereira LS, Flores-Garcia Y, O'Connor J, Flynn BJ, Schön A, Hurlburt NK, Dillon M, Yang ASP, Fabra-García A, Idris AH, Mayer BT, Gerber MW, Gottardo R, Mason RD, ... ... Zavala F, et al. A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver. Immunity. PMID 32946741 DOI: 10.1016/J.Immuni.2020.08.014  1
2020 Suscovich TJ, Fallon JK, Das J, Demas AR, Crain J, Linde CH, Michell A, Natarajan H, Arevalo C, Broge T, Linnekin T, Kulkarni V, Lu R, Slein MD, Luedemann C, ... ... Zavala F, et al. Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination. Science Translational Medicine. 12. PMID 32718991 DOI: 10.1126/Scitranslmed.Abb4757  1
2020 Raghunandan R, Mayer BT, Flores-Garcia Y, Gerber MW, Gottardo R, Jhun H, Herrera SM, Perez-Ramos DW, Locke E, King CR, Zavala F. Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein. Malaria Journal. 19: 113. PMID 32183833 DOI: 10.1186/S12936-020-03181-0  1
2020 Oyen D, Torres JL, Aoto PC, Flores-Garcia Y, Binter S, Pholcharee T, Carroll S, Reponen S, Wash R, Liang Q, Lemiale F, Locke E, Bradley A, King CR, Emerling D, ... ... Zavala F, et al. Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein. Plos Pathogens. 16: e1008373. PMID 32150583 DOI: 10.1371/Journal.Ppat.1008373  1
2019 Pholcharee T, Oyen D, Torres JL, Flores-Garcia Y, Martin GM, Gonzalez-Paez G, Emerling D, Volkmuth W, Locke E, King CR, Zavala F, Ward AB, Wilson IA. Diverse antibody responses to conserved structural motifs in Plasmodium falciparum circumsporozoite protein. Journal of Molecular Biology. PMID 31883801 DOI: 10.1016/J.Jmb.2019.12.029  1
2019 Flores-Garcia Y, Herrera SM, Jhun H, Pérez-Ramos DW, King CR, Locke E, Raghunandan R, Zavala F. Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages. Malaria Journal. 18: 426. PMID 31849326 DOI: 10.1186/S12936-019-3055-9  1
2019 Sinnis P, Zavala F. Reply to Vanderberg, "Further Mechanisms and Locations in Which Antisporozoite Antibodies Neutralize Malaria Sporozoites". Mbio. 10. PMID 31506316 DOI: 10.1128/Mbio.02108-19  1
2019 Vom Steeg LG, Flores-Garcia Y, Zavala F, Klein SL. Irradiated sporozoite vaccination induces sex-specific immune responses and protection against malaria in mice. Vaccine. PMID 31262583 DOI: 10.1016/j.vaccine.2019.06.075  1
2018 Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, ... ... Zavala F, et al. Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nature Medicine. PMID 30552419 DOI: 10.1038/S41591-018-0315-0  1
2018 Flores-Garcia Y, Nasir G, Hopp CS, Munoz C, Balaban AE, Zavala F, Sinnis P. Antibody-Mediated Protection against Sporozoites Begins at the Dermal Inoculation Site. Mbio. 9. PMID 30459199 DOI: 10.1128/Mbio.02194-18  1
2018 Oyen D, Torres JL, Wille-Reece U, Ockenhouse CF, Emerling D, Glanville J, Volkmuth W, Flores-Garcia Y, Zavala F, Ward AB, King CR, Wilson IA. Erratum: Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein (Proceedings of the National Academy of Sciences of the United States of America (2017) 114 (E10438–E10445) DOI: 10.1073/pnas.1715812114) Proceedings of the National Academy of Sciences of the United States of America. 115. PMID 29891667 DOI: 10.1073/Pnas.1808460115  1
2018 Seder RA, Zavala F. Ruth S. Nussenzweig (1928-2018). Nature. 557: 310. PMID 29752450 DOI: 10.1038/D41586-018-05102-3  0.01
2018 Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Scho N A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, ... ... Zavala F, et al. A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nature Medicine. PMID 29554083 DOI: 10.1038/Nm.4512  1
2017 Oyen D, Torres JL, Wille-Reece U, Ockenhouse CF, Emerling D, Glanville J, Volkmuth W, Flores-Garcia Y, Zavala F, Ward AB, King CR, Wilson IA. Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 29138320 DOI: 10.1073/Pnas.1715812114  1
2017 Espinosa DA, Christensen D, Muñoz C, Singh S, Locke E, Andersen P, Zavala F. Robust antibody and CD8(+) T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection. Npj Vaccines. 2. PMID 28936360 DOI: 10.1038/s41541-017-0011-y  1
2017 Urakami A, Sakurai A, Ishikawa M, Yap ML, Flores-Garcia Y, Haseda Y, Aoshi T, Zavala FP, Rossmann MG, Kuno S, Ueno R, Akahata W. Development of a novel virus-like particle vaccine platform that mimics immature form of alphavirus. Clinical and Vaccine Immunology : Cvi. PMID 28515133 DOI: 10.1128/Cvi.00090-17  1
2017 Long CA, Zavala F. Immune Responses in Malaria. Cold Spring Harbor Perspectives in Medicine. PMID 28389518 DOI: 10.1101/cshperspect.a025577  0.01
2017 Luo K, Zavala F, Gordy J, Zhang H, Markham RB. Extended protection capabilities of an immature dendritic-cell targeting malaria sporozoite vaccine. Vaccine. PMID 28342669 DOI: 10.1016/j.vaccine.2017.03.052  1
2017 Vijayan A, Mejías-Pérez E, Espinosa DA, Raman SC, Sorzano COS, Zavala F, Esteban M. A Prime/Boost PfCS14K/MVA-sPfCS Vaccination Protocol Generates Robust CD8 T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite Protein and Protects Mice against Malaria. Clinical and Vaccine Immunology : Cvi. 24. PMID 28298290 DOI: 10.1128/CVI.00494-16  1
2017 Aguiar AC, Figueiredo FJ, Neuenfeldt PD, Katsuragawa TH, Drawanz BB, Cunico W, Sinnis P, Zavala F, Krettli AU. Primaquine-thiazolidinones block malaria transmission and development of the liver exoerythrocytic forms. Malaria Journal. 16: 110. PMID 28279180 DOI: 10.1186/S12936-017-1755-6  1
2016 Espinosa DA, Vega-Rodriguez J, Flores-Garcia Y, Noe AR, Muñoz C, Coleman R, Bruck T, Haney K, Stevens A, Retallack D, Allen J, Vedvick TS, Fox CB, Reed SG, Howard RF, ... ... Zavala F, et al. The P. falciparum Cell-Traversal Protein for Ookinetes and Sporozoites as a Candidate for Pre-Erythrocytic and Transmission-Blocking Vaccines. Infection and Immunity. PMID 27895131 DOI: 10.1128/IAI.00498-16  1
2016 Long CA, Zavala F. Malaria vaccines and human immune responses. Current Opinion in Microbiology. 32: 96-102. PMID 27262417 DOI: 10.1016/j.mib.2016.04.006  1
2016 Espinosa DA, Radtke AJ, Zavala F. Development and Assessment of Transgenic Rodent Parasites for the Preclinical Evaluation of Malaria Vaccines. Methods in Molecular Biology (Clifton, N.J.). 1403: 583-601. PMID 27076155 DOI: 10.1007/978-1-4939-3387-7_33  1
2016 Cockburn IA, Zavala F. Dendritic cell function and antigen presentation in malaria. Current Opinion in Immunology. 40: 1-6. PMID 26845735 DOI: 10.1016/J.Coi.2016.01.010  1
2015 Whitacre DC, Espinosa DA, Peters CJ, Jones JE, Tucker AE, Peterson DL, Zavala FP, Milich DR. P. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections. Plos One. 10: e0124856. PMID 25933001 DOI: 10.1371/journal.pone.0124856  1
2015 Radtke AJ, Tse SW, Zavala F. From the draining lymph node to the liver: the induction and effector mechanisms of malaria-specific CD8+ T cells. Seminars in Immunopathology. 37: 211-20. PMID 25917387 DOI: 10.1007/S00281-015-0479-3  1
2015 Bijker EM, Nganou-Makamdop K, van Gemert GJ, Zavala F, Cockburn I, Sauerwein RW. Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria. Malaria Journal. 14: 130. PMID 25889324 DOI: 10.1186/s12936-015-0626-2  0.01
2015 Espinosa DA, Gutierrez GM, Rojas-López M, Noe AR, Shi L, Tse SW, Sinnis P, Zavala F. Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies. The Journal of Infectious Diseases. PMID 25762791 DOI: 10.1093/Infdis/Jiv154  1
2015 Radtke AJ, Kastenmüller W, Espinosa DA, Gerner MY, Tse SW, Sinnis P, Germain RN, Zavala FP, Cockburn IA. Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses. Plos Pathogens. 11: e1004637. PMID 25658939 DOI: 10.1371/Journal.Ppat.1004637  1
2015 Karen KA, Deal C, Adams RJ, Nielsen C, Ward C, Espinosa DA, Xie J, Zavala F, Ketner G. A replicating adenovirus capsid display recombinant elicits antibodies against Plasmodium falciparum sporozoites in Aotus nancymaae monkeys. Infection and Immunity. 83: 268-75. PMID 25368113 DOI: 10.1128/Iai.02626-14  1
2014 Noe AR, Espinosa D, Li X, Coelho-Dos-Reis JG, Funakoshi R, Giardina S, Jin H, Retallack DM, Haverstock R, Allen JR, Vedvick TS, Fox CB, Reed SG, Ayala R, Roberts B, ... ... Zavala F, et al. A full-length Plasmodium falciparum recombinant circumsporozoite protein expressed by Pseudomonas fluorescens platform as a malaria vaccine candidate. Plos One. 9: e107764. PMID 25247295 DOI: 10.1371/Journal.Pone.0107764  1
2014 Deal C, Balazs AB, Espinosa DA, Zavala F, Baltimore D, Ketner G. Vectored antibody gene delivery protects against Plasmodium falciparum sporozoite challenge in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 12528-32. PMID 25114213 DOI: 10.1073/Pnas.1407362111  1
2014 Tse SW, Radtke AJ, Espinosa DA, Cockburn IA, Zavala F. The chemokine receptor CXCR6 is required for the maintenance of liver memory CD8⁺ T cells specific for infectious pathogens. The Journal of Infectious Diseases. 210: 1508-16. PMID 24823625 DOI: 10.1093/Infdis/Jiu281  1
2014 Luo K, Zhang H, Zavala F, Biragyn A, Espinosa DA, Markham RB. Fusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilities. Plos One. 9: e90413. PMID 24599116 DOI: 10.1371/Journal.Pone.0090413  1
2014 Sack BK, Miller JL, Vaughan AM, Douglass A, Kaushansky A, Mikolajczak S, Coppi A, Gonzalez-Aseguinolaza G, Tsuji M, Zavala F, Sinnis P, Kappe SH. Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum. Infection and Immunity. 82: 808-17. PMID 24478094 DOI: 10.1128/Iai.01249-13  1
2014 Cockburn IA, Tse SW, Zavala F. CD8+ T cells eliminate liver-stage Plasmodium berghei parasites without detectable bystander effect. Infection and Immunity. 82: 1460-4. PMID 24421043 DOI: 10.1128/IAI.01500-13  1
2013 Ménard R, Tavares J, Cockburn I, Markus M, Zavala F, Amino R. Looking under the skin: the first steps in malarial infection and immunity. Nature Reviews. Microbiology. 11: 701-12. PMID 24037451 DOI: 10.1038/Nrmicro3111  1
2013 Espinosa DA, Yadava A, Angov E, Maurizio PL, Ockenhouse CF, Zavala F. Development of a chimeric Plasmodium berghei strain expressing the repeat region of the P. vivax circumsporozoite protein for in vivo evaluation of vaccine efficacy. Infection and Immunity. 81: 2882-7. PMID 23716612 DOI: 10.1128/Iai.00461-13  1
2013 Cockburn IA, Amino R, Kelemen RK, Kuo SC, Tse SW, Radtke A, Mac-Daniel L, Ganusov VV, Zavala F, Ménard R. In vivo imaging of CD8+ T cell-mediated elimination of malaria liver stages. Proceedings of the National Academy of Sciences of the United States of America. 110: 9090-5. PMID 23674673 DOI: 10.1073/Pnas.1303858110  1
2013 Tse SW, Cockburn IA, Zhang H, Scott AL, Zavala F. Unique transcriptional profile of liver-resident memory CD8+ T cells induced by immunization with malaria sporozoites. Genes and Immunity. 14: 302-9. PMID 23594961 DOI: 10.1038/gene.2013.20  1
2013 Kastenmüller K, Espinosa DA, Trager L, Stoyanov C, Salazar AM, Pokalwar S, Singh S, Dutta S, Ockenhouse CF, Zavala F, Seder RA. Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice. Infection and Immunity. 81: 789-800. PMID 23275094 DOI: 10.1128/Iai.01108-12  1
2013 Chen YC, Zavala F. Development and use of TCR transgenic mice for malaria immunology research. Methods in Molecular Biology (Clifton, N.J.). 923: 481-91. PMID 22990799 DOI: 10.1007/978-1-62703-026-7_33  1
2012 Sinnis P, Zavala F. The skin: where malaria infection and the host immune response begin. Seminars in Immunopathology. 34: 787-92. PMID 23053392 DOI: 10.1007/S00281-012-0345-5  1
2012 Vijayan A, Gómez CE, Espinosa DA, Goodman AG, Sanchez-Sampedro L, Sorzano CO, Zavala F, Esteban M. Adjuvant-like effect of vaccinia virus 14K protein: a case study with malaria vaccine based on the circumsporozoite protein. Journal of Immunology (Baltimore, Md. : 1950). 188: 6407-17. PMID 22615208 DOI: 10.4049/Jimmunol.1102492  1
2011 Tse SW, Radtke AJ, Zavala F. Induction and maintenance of protective CD8+ T cells against malaria liver stages: implications for vaccine development. MemóRias Do Instituto Oswaldo Cruz. 106: 172-8. PMID 21881772  1
2011 Cockburn IA, Tse SW, Radtke AJ, Srinivasan P, Chen YC, Sinnis P, Zavala F. Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo. Plos Pathogens. 7: e1001318. PMID 21445239 DOI: 10.1371/Journal.Ppat.1001318  1
2011 Overstreet MG, Chen YC, Cockburn IA, Tse SW, Zavala F. CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites. Plos One. 6: e15948. PMID 21245909 DOI: 10.1371/Journal.Pone.0015948  1
2011 Palma C, Overstreet MG, Guedon JM, Hoiczyk E, Ward C, Karen KA, Zavala F, Ketner G. Adenovirus particles that display the Plasmodium falciparum circumsporozoite protein NANP repeat induce sporozoite-neutralizing antibodies in mice. Vaccine. 29: 1683-9. PMID 21199707 DOI: 10.1016/J.Vaccine.2010.12.040  1
2010 Cockburn IA, Chen YC, Overstreet MG, Lees JR, van Rooijen N, Farber DL, Zavala F. Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites. Plos Pathogens. 6: e1000877. PMID 20463809 DOI: 10.1371/Journal.Ppat.1000877  1
2010 Riley EM, Couper KN, Helmby H, Hafalla JC, de Souza JB, Langhorne J, Jarra WB, Zavala F. Neuropathogenesis of human and murine malaria. Trends in Parasitology. 26: 277-8. PMID 20338809 DOI: 10.1016/J.Pt.2010.03.002  1
2010 Noland GS, Chowdhury DR, Urban JF, Zavala F, Kumar N. Helminth infection impairs the immunogenicity of a Plasmodium falciparum DNA vaccine, but not irradiated sporozoites, in mice. Vaccine. 28: 2917-23. PMID 20188676 DOI: 10.1016/J.Vaccine.2010.02.055  1
2010 Overstreet MG, Freyberger H, Cockburn IA, Chen YC, Tse SW, Zavala F. CpG-enhanced CD8+ T-cell responses to peptide immunization are severely inhibited by B cells. European Journal of Immunology. 40: 124-33. PMID 19830730 DOI: 10.1002/Eji.200939493  1
2008 Overstreet MG, Cockburn IA, Chen YC, Zavala F. Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response. Immunological Reviews. 225: 272-83. PMID 18837788 DOI: 10.1111/J.1600-065X.2008.00671.X  1
2008 Dalai SK, Mirshahidi S, Morrot A, Zavala F, Sadegh-Nasseri S. Anergy in memory CD4+ T cells is induced by B cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 3221-31. PMID 18713993 DOI: 10.4049/Jimmunol.181.5.3221  1
2008 Srivastava K, Cockburn IA, Swaim A, Thompson LE, Tripathi A, Fletcher CA, Shirk EM, Sun H, Kowalska MA, Fox-Talbot K, Sullivan D, Zavala F, Morrell CN. Platelet factor 4 mediates inflammation in experimental cerebral malaria. Cell Host & Microbe. 4: 179-87. PMID 18692777 DOI: 10.1016/J.Chom.2008.07.003  1
2008 Chakravarty S, Baldeviano GC, Overstreet MG, Zavala F. Effector CD8+ T lymphocytes against liver stages of Plasmodium yoelii do not require gamma interferon for antiparasite activity. Infection and Immunity. 76: 3628-31. PMID 18519561 DOI: 10.1128/Iai.00471-08  1
2008 Sinnis P, Zavala F. The skin stage of malaria infection: biology and relevance to the malaria vaccine effort. Future Microbiology. 3: 275-8. PMID 18505393 DOI: 10.2217/17460913.3.3.275  1
2008 McKelvie ND, Khan SA, Karavolos MH, Bulmer DM, Lee JJ, DeMarco R, Maskell DJ, Zavala F, Hormaeche CE, Khan CM. Genetic detoxification of an aroA Salmonella enterica serovar Typhimurium vaccine strain does not compromise protection against virulent Salmonella and enhances the immune responses towards a protective malarial antigen. Fems Immunology and Medical Microbiology. 52: 237-46. PMID 18177343 DOI: 10.1111/J.1574-695X.2007.00368.X  0.01
2008 Cockburn IA, Chakravarty S, Overstreet MG, García-Sastre A, Zavala F. Memory CD8+ T cell responses expand when antigen presentation overcomes T cell self-regulation. Journal of Immunology (Baltimore, Md. : 1950). 180: 64-71. PMID 18097005 DOI: 10.4049/Jimmunol.180.1.64  1
2007 Hafalla JC, Rai U, Bernal-Rubio D, Rodriguez A, Zavala F. Efficient development of plasmodium liver stage-specific memory CD8+ T cells during the course of blood-stage malarial infection. The Journal of Infectious Diseases. 196: 1827-35. PMID 18190264 DOI: 10.1086/522965  1
2007 Chakravarty S, Cockburn IA, Kuk S, Overstreet MG, Sacci JB, Zavala F. CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes. Nature Medicine. 13: 1035-41. PMID 17704784 DOI: 10.1038/Nm1628  1
2007 Melendi GA, Zavala F, Buchholz UJ, Boivin G, Collins PL, Kleeberger SR, Polack FP. Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus. Journal of Virology. 81: 11461-7. PMID 17670840 DOI: 10.1128/JVI.02423-06  1
2007 Cockburn IA, Zavala F. T cell memory in malaria. Current Opinion in Immunology. 19: 424-9. PMID 17624749 DOI: 10.1016/j.coi.2007.05.008  1
2007 Acacia de Sa Pinheiro A, Morrot A, Chakravarty S, Overstreet M, Bream JH, Irusta PM, Zavala F. IL-4 induces a wide-spectrum intracellular signaling cascade in CD8+ T cells. Journal of Leukocyte Biology. 81: 1102-10. PMID 17200144 DOI: 10.1189/Jlb.0906583  1
2007 Li S, Locke E, Bruder J, Clarke D, Doolan DL, Havenga MJ, Hill AV, Liljestrom P, Monath TP, Naim HY, Ockenhouse C, Tang DC, Van Kampen KR, Viret JF, Zavala F, et al. Viral vectors for malaria vaccine development. Vaccine. 25: 2567-74. PMID 16914237 DOI: 10.1016/j.vaccine.2006.07.035  1
2006 Kumar KA, Sano G, Boscardin S, Nussenzweig RS, Nussenzweig MC, Zavala F, Nussenzweig V. The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites. Nature. 444: 937-40. PMID 17151604 DOI: 10.1038/Nature05361  1
2006 Hafalla JC, Rai U, Morrot A, Bernal-Rubio D, Zavala F, Rodriguez A. Priming of CD8+ T cell responses following immunization with heat-killed Plasmodium sporozoites. European Journal of Immunology. 36: 1179-86. PMID 16598821 DOI: 10.1002/eji.200535712  1
2006 Morrot A, Cockburn IA, Overstreet M, Rodríguez D, Zavala F. Protective CD8+ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression. Infection and Immunity. 74: 2495-7. PMID 16552087 DOI: 10.1128/Iai.74.4.2495-2497.2006  1
2006 Boscardin SB, Hafalla JC, Masilamani RF, Kamphorst AO, Zebroski HA, Rai U, Morrot A, Zavala F, Steinman RM, Nussenzweig RS, Nussenzweig MC. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. The Journal of Experimental Medicine. 203: 599-606. PMID 16505139 DOI: 10.1084/Jem.20051639  1
2006 Stevenson MM, Zavala F. Immunology of malaria infections Parasite Immunology. 28: 1-4. PMID 16438670 DOI: 10.1111/j.1365-3024.2006.00797.x  1
2005 Morrot A, Hafalla JC, Cockburn IA, Carvalho LH, Zavala F. IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites. The Journal of Experimental Medicine. 202: 551-60. PMID 16087712 DOI: 10.1084/Jem.20042463  1
2004 del Portillo HA, Lanzer M, Rodriguez-Malaga S, Zavala F, Fernandez-Becerra C. Variant genes and the spleen in Plasmodium vivax malaria. International Journal For Parasitology. 34: 1547-54. PMID 15582531 DOI: 10.1016/J.Ijpara.2004.10.012  1
2004 Morrot A, Zavala F. Regulation of the CD8+ T cell responses against Plasmodium liver stages in mice. International Journal For Parasitology. 34: 1529-34. PMID 15582529 DOI: 10.1016/j.ijpara.2004.10.001  1
2004 Tongren JE, Zavala F, Roos DS, Riley EM. Malaria vaccines: if at first you don't succeed... Trends in Parasitology. 20: 604-10. PMID 15522671 DOI: 10.1016/j.pt.2004.09.005  1
2004 Morrot A, Zavala F. Effector and memory CD8+ T cells as seen in immunity to malaria. Immunological Reviews. 201: 291-303. PMID 15361248 DOI: 10.1111/j.0105-2896.2004.00175.x  1
2003 Hafalla JC, Morrot A, Sano G, Milon G, Lafaille JJ, Zavala F. Early self-regulatory mechanisms control the magnitude of CD8+ T cell responses against liver stages of murine malaria. Journal of Immunology (Baltimore, Md. : 1950). 171: 964-70. PMID 12847268 DOI: 10.4049/Jimmunol.171.2.964  1
2003 Tsuji M, Zavala F. T cells as mediators of protective immunity against liver stages of Plasmodium. Trends in Parasitology. 19: 88-93. PMID 12586477 DOI: 10.1016/S1471-4922(02)00053-3  1
2002 Jung S, Unutmaz D, Wong P, Sano G, De los Santos K, Sparwasser T, Wu S, Vuthoori S, Ko K, Zavala F, Pamer EG, Littman DR, Lang RA. In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity. 17: 211-20. PMID 12196292 DOI: 10.1016/S1074-7613(02)00365-5  1
2002 Hafalla JC, Sano G, Carvalho LH, Morrot A, Zavala F. Short-term antigen presentation and single clonal burst limit the magnitude of the CD8(+) T cell responses to malaria liver stages. Proceedings of the National Academy of Sciences of the United States of America. 99: 11819-24. PMID 12185251 DOI: 10.1073/Pnas.182189999  1
2002 Carvalho LH, Sano G, Hafalla JC, Morrot A, Curotto de Lafaille MA, Zavala F. IL-4-secreting CD4+ T cells are crucial to the development of CD8+ T-cell responses against malaria liver stages. Nature Medicine. 8: 166-70. PMID 11821901 DOI: 10.1038/nm0202-166  1
1996 Takita-Sonoda Y, Tsuji M, Kamboj K, Nussenzweig RS, Clavijo P, Zavala F. Plasmodium yoelii: peptide immunization induces protective CD4+ T cells against a previously unrecognized cryptic epitope of the circumsporozoite protein. Experimental Parasitology. 84: 223-30. PMID 8932772 DOI: 10.1006/Expr.1996.0108  1
1996 Tsuji M, Eyster CL, O'Brien RL, Born WK, Bapna M, Reichel M, Nussenzweig RS, Zavala F. Phenotypic and functional properties of murine gamma delta T cell clones derived from malaria immunized, alpha beta T cell-deficient mice. International Immunology. 8: 359-66. PMID 8728988 DOI: 10.1093/Intimm/8.3.359  1
1994 Tsuji M, Mombaerts P, Lefrancois L, Nussenzweig RS, Zavala F, Tonegawa S. Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 345-9. PMID 8278391 DOI: 10.1073/Pnas.91.1.345  1
1994 Tsuji M, Mattei D, Nussenzweig RS, Eichinger D, Zavala F. Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites Parasitology Research. 80: 16-21. PMID 8153120 DOI: 10.1007/Bf00932618  1
1990 Zavala F, Chai S. Protective anti-sporozoite antibodies induced by a chemically defined synthetic vaccine Immunology Letters. 25: 271-274. PMID 1704349 DOI: 10.1016/0165-2478(90)90126-B  1
1990 Tam JP, Clavijo P, Lu YA, Nussenzweig V, Nussenzweig R, Zavala F. Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria. The Journal of Experimental Medicine. 171: 299-306. PMID 1688609 DOI: 10.1084/Jem.171.1.299  1
1989 Davis JR, Murphy JR, Clyde DF, Baqar S, Cochrane AH, Zavala F, Nussenzweig RS. Estimate of Plasmodium falciparum sporozoite content of Anopheles stephensi used to challenge human volunteers. The American Journal of Tropical Medicine and Hygiene. 40: 128-30. PMID 2645802 DOI: 10.4269/ajtmh.1989.40.128  1
1989 Satterthwait AC, Arrhenius T, Hagopian RA, Zavala F, Nussenzweig V, Lerner RA. The conformational restriction of synthetic peptides, including a malaria peptide, for use as immunogens. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 323: 565-72. PMID 2569211 DOI: 10.1098/Rstb.1989.0036  1
1989 Romero P, Maryanski JL, Corradin G, Nussenzweig RS, Nussenzweig V, Zavala F. Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature. 341: 323-6. PMID 2477703 DOI: 10.1038/341323A0  1
1988 Vijaya S, Elango N, Zavala F, Moss B. Transport to the cell surface of a peptide sequence attached to the truncated C terminus of an N-terminally anchored integral membrane protein. Molecular and Cellular Biology. 8: 1709-14. PMID 3380095 DOI: 10.1128/mcb.8.4.1709-1714.1988  0.01
1988 Satterthwait AC, Arrhenius T, Hagopian RA, Zavala F, Nussenzweig V, Lerner RA. Conformational restriction of peptidyl immunogens with covalent replacements for the hydrogen bond. Vaccine. 6: 99-103. PMID 3291460 DOI: 10.1016/S0264-410X(88)80007-0  1
1988 Romero PJ, Tam JP, Schlesinger D, Clavijo P, Gibson H, Barr PJ, Nussenzweig RS, Nussenzweig V, Zavala F. Multiple T helper cell epitopes of the circumsporozoite protein of Plasmodium berghei. European Journal of Immunology. 18: 1951-7. PMID 2464495 DOI: 10.1002/Eji.1830181213  1
1987 Zavala F, Tam JP, Barr PJ, Romero PJ, Ley V, Nussenzweig RS, Nussenzweig V. Synthetic peptide vaccine confers protection against murine malaria. The Journal of Experimental Medicine. 166: 1591-6. PMID 3316473 DOI: 10.1084/Jem.166.5.1591  1
1986 Masuda A, Zavala F, Nussenzweig V, Nussenzweig RS. Monoclonal anti-gametocyte antibodies identify an antigen present in all blood stages of Plasmodium falciparum. Molecular and Biochemical Parasitology. 19: 213-22. PMID 3526145 DOI: 10.1016/0166-6851(86)90003-4  1
1985 Collins FH, Gwadz RW, Koontz LC, Zavala F, Nussenzweig RS. Laboratory assessment of a species-specific radioimmunoassay for the detection of malaria sporozoites in mosquitoes (Diptera: Culicidae). Journal of Medical Entomology. 22: 121-9. PMID 3981555 DOI: 10.1093/Jmedent/22.2.121  1
1985 Zavala F, Tam JP, Hollingdale MR, Cochrane AH, Quakyi I, Nussenzweig RS, Nussenzweig V. Rationale for development of a synthetic vaccine against Plasmodium falciparum malaria. Science (New York, N.Y.). 228: 1436-40. PMID 2409595 DOI: 10.1126/Science.2409595  1
1984 Collins FH, Zavala F, Graves PM, Cochrane AH, Gwadz RW, Akoh J, Nussenzweig RS. First field trial of an immunoradiometric assay for the detection of malaria sporozoites in mosquitoes. The American Journal of Tropical Medicine and Hygiene. 33: 538-43. PMID 6383093 DOI: 10.4269/Ajtmh.1984.33.538  1
1984 Burkot TR, Zavala F, Gwadz RW, Collins FH, Nussenzweig RS, Roberts DR. Identification of malaria-infected mosquitoes by a two-site enzyme-linked immunosorbent assay. The American Journal of Tropical Medicine and Hygiene. 33: 227-31. PMID 6370003 DOI: 10.4269/Ajtmh.1984.33.227  1
1982 Zavala F, Gwadz RW, Collins FH, Nussenzweig RS, Nussenzweig V. Monoclonal antibodies to circumsporozoite proteins identify the species of malaria parasite in infected mosquitoes. Nature. 299: 737-8. PMID 7121602 DOI: 10.1038/299737A0  1
1982 Potocnjak P, Zavala F, Nussenzweig R, Nussenzweig V. Inhibition of idiotype - Anti-idiotype interaction for detection of a parasite antigen: A new immunoassay Science. 216: 1637-1639. PMID 6122269 DOI: 10.1126/Science.6122269  1
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