Stefanie N. Vogel - Publications

Molecular Microbiology and Immunology University of Maryland School of Medicine, Baltimore, MD, United States 
Immunology, Molecular Biology

188 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shirey KA, Blanco JCG, Vogel SN. Targeting TLR4 Signaling to Blunt Viral-Mediated Acute Lung Injury. Frontiers in Immunology. 12: 705080. PMID 34282358 DOI: 10.3389/fimmu.2021.705080  0.32
2021 Cole LE, Elkins KL, Michalek SM, Qureshi N, Eaton LJ, Rallabhandi P, Cuesta N, Vogel SN. Correction: Immunologic Consequences of Live Vaccine Strain Infection: Role of the Innate Immune Response in Infection and Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 34272234 DOI: 10.4049/jimmunol.2100505  0.64
2021 Richard K, Piepenbrink KH, Shirey KA, Gopalakrishnan A, Nallar S, Prantner DJ, Perkins DJ, Lai W, Vlk A, Toshchakov VY, Feng C, Fanaroff R, Medvedev AE, Blanco JCG, Vogel SN. A mouse model of human TLR4 D299G/T399I SNPs reveals mechanisms of altered LPS and pathogen responses. The Journal of Experimental Medicine. 218. PMID 33216117 DOI: 10.1084/jem.20200675  0.32
2020 Polumuri S, Perkins DJ, Vogel SN. cAMP levels regulate macrophage alternative activation marker expression. Innate Immunity. 1753425920975082. PMID 33241977 DOI: 10.1177/1753425920975082  0.48
2020 Richard K, Perkins DJ, Harberts EM, Song Y, Gopalakrishnan A, Shirey KA, Lai W, Vlk A, Mahurkar A, Nallar S, Hawkins LD, Ernst RK, Vogel SN. Dissociation of TRIF bias and adjuvanticity. Vaccine. PMID 32389496 DOI: 10.1016/J.Vaccine.2020.04.042  0.32
2020 Doran SJ, Henry RJ, Shirey KA, Barrett JP, Ritzel RM, Lai W, Blanco JC, Faden AI, Vogel SN, Loane DJ. Early or Late Bacterial Lung Infection Increases Mortality After Traumatic Brain Injury in Male Mice and Chronically Impairs Monocyte Innate Immune Function. Critical Care Medicine. PMID 32149839 DOI: 10.1097/Ccm.0000000000004273  0.32
2020 Shirey KA, Lai W, Brown LJ, Blanco JCG, Beadenkopf R, Wang Y, Vogel SN, Snyder GA. Select targeting of intracellular Toll-interleukin-1 receptor resistance domains for protection against influenza-induced disease. Innate Immunity. 26: 26-34. PMID 31955622 DOI: 10.1177/1753425919846281  0.32
2019 Shirey KA, Perkins DJ, Lai W, Zhang W, Fernando LR, Gusovsky F, Blanco JCG, Vogel SN. Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection. Mbio. 10. PMID 31064834 DOI: 10.1128/Mbio.00810-19  0.32
2018 Shirey KA, Sunday ME, Lai W, Patel MC, Blanco JCG, Cuttitta F, Vogel SN. Novel role of gastric releasing peptide-mediated signaling in the host response to influenza infection. Mucosal Immunology. PMID 30327535 DOI: 10.1038/S41385-018-0081-9  0.48
2018 Patel MC, Shirey KA, Boukhvalova MS, Vogel SN, Blanco JCG. Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections. Mbio. 9. PMID 29535197 DOI: 10.1128/Mbio.00246-18  0.32
2017 Prantner D, Shirey KA, Lai W, Lu W, Cole AM, Vogel SN, Garzino-Demo A. The θ-defensin retrocyclin 101 inhibits TLR4- and TLR2-dependent signaling and protects mice against influenza infection. Journal of Leukocyte Biology. PMID 28729359 DOI: 10.1189/Jlb.2A1215-567Rr  0.32
2017 Perrin-Cocon L, Aublin-Gex A, Sestito SE, Shirey KA, Patel MC, André P, Blanco JC, Vogel SN, Peri F, Lotteau V. TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection. Scientific Reports. 7: 40791. PMID 28106157 DOI: 10.1038/Srep40791  0.32
2016 Perkins DJ, Patel MC, Blanco JC, Vogel SN. Epigenetic Mechanisms Governing Innate Inflammatory Responses. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 36: 454-61. PMID 27379867 DOI: 10.1089/jir.2016.0003  0.64
2016 Richard K, Vogel SN, Perkins DJ. Type I interferon licenses enhanced innate recognition and transcriptional responses to Franciscella tularensis live vaccine strain. Innate Immunity. PMID 27231145 DOI: 10.1177/1753425916650027  0.64
2016 Keegan AD, Shirey KA, Bagdure D, Blanco J, Viscardi RM, Vogel SN. Enhanced allergic responsiveness after early childhood infection with respiratory viruses: are long-lived alternatively-activated macrophages the missing link? Pathogens and Disease. PMID 27178560 DOI: 10.1093/Femspd/Ftw047  0.32
2016 Perkins DJ, Vogel SN. Inflammation: Species-specific TLR signalling - insight into human disease. Nature Reviews. Rheumatology. 12: 198-200. PMID 27006311 DOI: 10.1038/Nrrheum.2016.36  0.64
2016 Shirey KA, Lai W, Patel MC, Pletneva LM, Pang C, Kurt-Jones E, Lipsky M, Roger T, Calandra T, Tracey KJ, Al-Abed Y, Bowie AG, Fasano A, Dinarello CA, Gusovsky F, ... ... Vogel SN, et al. Novel strategies for targeting innate immune responses to influenza. Mucosal Immunology. PMID 26813341 DOI: 10.1038/Mi.2015.141  0.64
2015 Perkins DJ, Rajaiah R, Tennant SM, Ramachandran G, Higginson EE, Dyson TN, Vogel SN. Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively. Journal of Immunology (Baltimore, Md. : 1950). 195: 2461-71. PMID 26202980 DOI: 10.4049/Jimmunol.1500105  0.64
2015 Rajaiah R, Perkins DJ, Ireland DD, Vogel SN. CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance. Proceedings of the National Academy of Sciences of the United States of America. 112: 8391-6. PMID 26106158 DOI: 10.1073/Pnas.1424980112  0.64
2015 Piao W, Shirey KA, Ru LW, Lai W, Szmacinski H, Snyder GA, Sundberg EJ, Lakowicz JR, Vogel SN, Toshchakov VY. A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza. Cell Reports. 11: 1941-1952. PMID 26095366 DOI: 10.1016/J.Celrep.2015.05.035  0.32
2015 Mistry P, Laird MH, Schwarz RS, Greene S, Dyson T, Snyder GA, Xiao TS, Chauhan J, Fletcher S, Toshchakov VY, MacKerell AD, Vogel SN. Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain. Proceedings of the National Academy of Sciences of the United States of America. 112: 5455-60. PMID 25870276 DOI: 10.1073/Pnas.1422576112  0.64
2015 Perkins DJ, Vogel SN. Space and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs). Cytokine. 74: 171-4. PMID 25819430 DOI: 10.1016/J.Cyto.2015.03.001  0.64
2015 Abraham C, Vogel SN, Perkins DJ. Signaling Mechanisms Regulating Innate Immune Responses Mucosal Immunology: Fourth Edition. 1: 605-622. DOI: 10.1016/B978-0-12-415847-4.00030-6  0.64
2014 Blanco JC, Boukhvalova MS, Perez DR, Vogel SN, Kajon A. Modeling Human Respiratory Viral Infections in the Cotton Rat (Sigmodon hispidus). Journal of Antivirals & Antiretrovirals. 6: 40-42. PMID 25635205 DOI: 10.4172/Jaa.1000093  0.64
2014 Patel MC, Shirey KA, Pletneva LM, Boukhvalova MS, Garzino-Demo A, Vogel SN, Blanco JC. Novel drugs targeting Toll-like receptors for antiviral therapy. Future Virology. 9: 811-829. PMID 25620999 DOI: 10.2217/Fvl.14.70  0.64
2014 Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, ... ... Vogel SN, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity. 41: 14-20. PMID 25035950 DOI: 10.1016/J.Immuni.2014.06.008  0.64
2014 Sheikh F, Dickensheets H, Gamero AM, Vogel SN, Donnelly RP. An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages. Journal of Leukocyte Biology. 96: 591-600. PMID 25024400 DOI: 10.1189/Jlb.2A0414-191R  0.64
2014 Shirey KA, Lai W, Pletneva LM, Finkelman FD, Feola DJ, Blanco JC, Vogel SN. Agents that increase AAM differentiation blunt RSV-mediated lung pathology. Journal of Leukocyte Biology. 96: 951-5. PMID 25009233 DOI: 10.1189/Jlb.4Hi0414-226R  0.64
2014 Richard K, Mann BJ, Stocker L, Barry EM, Qin A, Cole LE, Hurley MT, Ernst RK, Michalek SM, Stein DC, Deshong P, Vogel SN. Novel catanionic surfactant vesicle vaccines protect against Francisella tularensis LVS and confer significant partial protection against F. tularensis Schu S4 strain. Clinical and Vaccine Immunology : Cvi. 21: 212-26. PMID 24351755 DOI: 10.1128/Cvi.00738-13  0.64
2014 Blanco JC, Boukhvalova MS, Pletneva LM, Shirey KA, Vogel SN. A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology. Vaccine. 32: 1495-500. PMID 24252693 DOI: 10.1016/J.Vaccine.2013.11.032  0.64
2014 Shirey KA, Lai W, Pletneva LM, Karp CL, Divanovic S, Blanco JC, Vogel SN. Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology. Mucosal Immunology. 7: 549-57. PMID 24064666 DOI: 10.1038/Mi.2013.71  0.64
2014 Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, ... ... Vogel SN, et al. Correction tp Macrophage activation and polarization: Nomenclature and experimental guidelines [Immunity, 41, 2014 (14-20)] Immunity. 41: 339-340. DOI: 10.1016/J.Immuni.2014.07.009  0.64
2013 Piao W, Ru LW, Piepenbrink KH, Sundberg EJ, Vogel SN, Toshchakov VY. Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain. Proceedings of the National Academy of Sciences of the United States of America. 110: 19036-41. PMID 24194546 DOI: 10.1073/Pnas.1313575110  0.64
2013 Feng C, Zhang L, Nguyen C, Vogel SN, Goldblum SE, Blackwelder WC, Cross AS. Neuraminidase reprograms lung tissue and potentiates lipopolysaccharide-induced acute lung injury in mice. Journal of Immunology (Baltimore, Md. : 1950). 191: 4828-37. PMID 24068662 DOI: 10.4049/Jimmunol.1202673  0.64
2013 Shah S, Bohsali A, Ahlbrand SE, Srinivasan L, Rathinam VA, Vogel SN, Fitzgerald KA, Sutterwala FS, Briken V. Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-β and AIM2 inflammasome-dependent IL-1β production via its ESX-1 secretion system. Journal of Immunology (Baltimore, Md. : 1950). 191: 3514-8. PMID 23997220 DOI: 10.4049/Jimmunol.1301331  0.64
2013 Doyle SL, Shirey KA, McGettrick AF, Kenny EF, Carpenter S, Caffrey BE, Gargan S, Quinn SR, Caamaño JH, Moynagh P, Vogel SN, O'Neill LA. Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15. The Journal of Biological Chemistry. 288: 25066-75. PMID 23873932 DOI: 10.1074/Jbc.M113.469122  0.64
2013 Perkins DJ, Polumuri SK, Pennini ME, Lai W, Xie P, Vogel SN. Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production. Plos Pathogens. 9: e1003479. PMID 23853595 DOI: 10.1371/Journal.Ppat.1003479  0.64
2013 Xiong Y, Pennini M, Vogel SN, Medvedev AE. IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance. Journal of Leukocyte Biology. 94: 291-300. PMID 23695305 DOI: 10.1189/Jlb.0812401  0.64
2013 Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, McAlees J, Gioannini TL, Weiss J, Chen WH, Ernst RK, Rossignol DP, Gusovsky F, Blanco JC, ... Vogel SN, et al. The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature. 497: 498-502. PMID 23636320 DOI: 10.1038/Nature12118  0.64
2013 Conlon J, Burdette DL, Sharma S, Bhat N, Thompson M, Jiang Z, Rathinam VA, Monks B, Jin T, Xiao TS, Vogel SN, Vance RE, Fitzgerald KA. Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid. Journal of Immunology (Baltimore, Md. : 1950). 190: 5216-25. PMID 23585680 DOI: 10.4049/Jimmunol.1300097  0.64
2013 Rajaiah R, Perkins DJ, Polumuri SK, Zhao A, Keegan AD, Vogel SN. Dissociation of endotoxin tolerance and differentiation of alternatively activated macrophages. Journal of Immunology (Baltimore, Md. : 1950). 190: 4763-72. PMID 23543762 DOI: 10.4049/Jimmunol.1202407  0.64
2013 Winters AH, Levan TD, Vogel SN, Chesko KL, Pollin TI, Viscardi RM. Single nucleotide polymorphism in toll-like receptor 6 is associated with a decreased risk for ureaplasma respiratory tract colonization and bronchopulmonary dysplasia in preterm infants. The Pediatric Infectious Disease Journal. 32: 898-904. PMID 23518821 DOI: 10.1097/Inf.0B013E31828Fc693  0.64
2013 Piao W, Vogel SN, Toshchakov VY. Inhibition of TLR4 signaling by TRAM-derived decoy peptides in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 190: 2263-72. PMID 23345333 DOI: 10.4049/Jimmunol.1202703  0.64
2013 Yang Z, Sun R, Grinchuk V, Fernández-Blanco JA, Blanco JA, Notari L, Bohl JA, McLean LP, Ramalingam TR, Wynn TA, Urban JF, Vogel SN, Shea-Donohue T, Zhao A. IL-33-induced alterations in murine intestinal function and cytokine responses are MyD88, STAT6, and IL-13 dependent. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G381-9. PMID 23257921 DOI: 10.1152/Ajpgi.00357.2012  0.64
2013 Pennini ME, Perkins DJ, Salazar AM, Lipsky M, Vogel SN. Complete dependence on IRAK4 kinase activity in TLR2, but not TLR4, signaling pathways underlies decreased cytokine production and increased susceptibility to Streptococcus pneumoniae infection in IRAK4 kinase-inactive mice. Journal of Immunology (Baltimore, Md. : 1950). 190: 307-16. PMID 23209321 DOI: 10.4049/Jimmunol.1201644  0.64
2013 Basran A, Jabeen M, Bingle L, Stokes CA, Dockrell DH, Whyte MK, Walmsley SR, Higgins KR, Vogel SN, Wilson HL, Prince LR, Prestwich EC, Sabroe RA, Parker LC, Sabroe I. Roles of neutrophils in the regulation of the extent of human inflammation through delivery of IL-1 and clearance of chemokines. Journal of Leukocyte Biology. 93: 7-19. PMID 22904343 DOI: 10.1189/Jlb.0512250  0.64
2012 Panicker LM, Miller D, Park TS, Patel B, Azevedo JL, Awad O, Masood MA, Veenstra TD, Goldin E, Stubblefield BK, Tayebi N, Polumuri SK, Vogel SN, Sidransky E, Zambidis ET, et al. Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 18054-9. PMID 23071332 DOI: 10.1073/Pnas.1207889109  0.64
2012 Prantner D, Perkins DJ, Lai W, Williams MS, Sharma S, Fitzgerald KA, Vogel SN. 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential. The Journal of Biological Chemistry. 287: 39776-88. PMID 23027866 DOI: 10.1074/Jbc.M112.382986  0.64
2012 Qualls JE, Subramanian C, Rafi W, Smith AM, Balouzian L, DeFreitas AA, Shirey KA, Reutterer B, Kernbauer E, Stockinger S, Decker T, Miyairi I, Vogel SN, Salgame P, Rock CO, et al. Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1. Cell Host & Microbe. 12: 313-23. PMID 22980328 DOI: 10.1016/J.Chom.2012.07.012  0.64
2012 Rallabhandi P, Phillips RL, Boukhvalova MS, Pletneva LM, Shirey KA, Gioannini TL, Weiss JP, Chow JC, Hawkins LD, Vogel SN, Blanco JC. Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2. Mbio. 3. PMID 22872782 DOI: 10.1128/Mbio.00218-12  0.64
2012 Couture LA, Piao W, Ru LW, Vogel SN, Toshchakov VY. Targeting Toll-like receptor (TLR) signaling by Toll/interleukin-1 receptor (TIR) domain-containing adapter protein/MyD88 adapter-like (TIRAP/Mal)-derived decoy peptides. The Journal of Biological Chemistry. 287: 24641-8. PMID 22648407 DOI: 10.1074/Jbc.M112.360925  0.64
2012 Polumuri SK, Jayakar GG, Shirey KA, Roberts ZJ, Perkins DJ, Pitha PM, Vogel SN. Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists. Journal of Immunology (Baltimore, Md. : 1950). 189: 50-60. PMID 22634618 DOI: 10.4049/Jimmunol.1003554  0.64
2012 Vogel SN. How discovery of Toll-mediated innate immunity in Drosophila impacted our understanding of TLR signaling (and vice versa). Journal of Immunology (Baltimore, Md. : 1950). 188: 5207-9. PMID 22611247 DOI: 10.4049/Jimmunol.1201050  0.64
2012 Marohn ME, Santiago AE, Shirey KA, Lipsky M, Vogel SN, Barry EM. Members of the Francisella tularensis phagosomal transporter subfamily of major facilitator superfamily transporters are critical for pathogenesis. Infection and Immunity. 80: 2390-401. PMID 22508856 DOI: 10.1128/Iai.00144-12  0.64
2012 Feng C, Stamatos NM, Dragan AI, Medvedev A, Whitford M, Zhang L, Song C, Rallabhandi P, Cole L, Nhu QM, Vogel SN, Geddes CD, Cross AS. Sialyl residues modulate LPS-mediated signaling through the Toll-like receptor 4 complex. Plos One. 7: e32359. PMID 22496731 DOI: 10.1371/Journal.Pone.0032359  0.64
2012 Figueroa L, Xiong Y, Song C, Piao W, Vogel SN, Medvedev AE. The Asp299Gly polymorphism alters TLR4 signaling by interfering with recruitment of MyD88 and TRIF. Journal of Immunology (Baltimore, Md. : 1950). 188: 4506-15. PMID 22474023 DOI: 10.4049/Jimmunol.1200202  0.64
2012 Liu A, Gong P, Hyun SW, Wang KZ, Cates EA, Perkins D, Bannerman DD, Puché AC, Toshchakov VY, Fang S, Auron PE, Vogel SN, Goldblum SE. TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia. The Journal of Biological Chemistry. 287: 16132-45. PMID 22447928 DOI: 10.1074/Jbc.M111.310102  0.64
2012 Yang Y, Ghosn EE, Cole LE, Obukhanych TV, Sadate-Ngatchou P, Vogel SN, Herzenberg LA, Herzenberg LA. Antigen-specific memory in B-1a and its relationship to natural immunity. Proceedings of the National Academy of Sciences of the United States of America. 109: 5388-93. PMID 22421135 DOI: 10.1073/Pnas.1121627109  0.64
2012 Yang Y, Ghosn EE, Cole LE, Obukhanych TV, Sadate-Ngatchou P, Vogel SN, Herzenberg LA, Herzenberg LA. Antigen-specific antibody responses in B-1a and their relationship to natural immunity. Proceedings of the National Academy of Sciences of the United States of America. 109: 5382-7. PMID 22421134 DOI: 10.1073/Pnas.1121631109  0.64
2012 Chen WH, Toapanta FR, Shirey KA, Zhang L, Giannelou A, Page C, Frieman MB, Vogel SN, Cross AS. Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza. Immunology Letters. 141: 227-34. PMID 22037624 DOI: 10.1016/J.Imlet.2011.10.009  0.64
2012 Beasley AS, Cotter RJ, Vogel SN, Inzana TJ, Qureshi AA, Qureshi N. A variety of novel lipid A structures obtained from Francisella tularensis live vaccine strain. Innate Immunity. 18: 268-78. PMID 21709054 DOI: 10.1177/1753425911401054  0.64
2012 Nhu QM, Shirey KA, Pennini ME, Stiltz J, Vogel SN. Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages. Innate Immunity. 18: 193-203. PMID 21239455 DOI: 10.1177/1753425910395044  0.64
2011 Cole LE, Mann BJ, Shirey KA, Richard K, Yang Y, Gearhart PJ, Chesko KL, Viscardi RM, Vogel SN. Role of TLR signaling in Francisella tularensis-LPS-induced, antibody-mediated protection against Francisella tularensis challenge. Journal of Leukocyte Biology. 90: 787-97. PMID 21750122 DOI: 10.1189/Jlb.0111014  0.64
2011 Reis J, Guan XQ, Kisselev AF, Papasian CJ, Qureshi AA, Morrison DC, Van Way CW, Vogel SN, Qureshi N. LPS-induced formation of immunoproteasomes: TNF-α and nitric oxide production are regulated by altered composition of proteasome-active sites. Cell Biochemistry and Biophysics. 60: 77-88. PMID 21455682 DOI: 10.1007/s12013-011-9182-8  0.64
2011 Reis J, Hassan F, Guan XQ, Shen J, Monaco JJ, Papasian CJ, Qureshi AA, Van Way CW, Vogel SN, Morrison DC, Qureshi N. The immunoproteasomes regulate LPS-induced TRIF/TRAM signaling pathway in murine macrophages. Cell Biochemistry and Biophysics. 60: 119-26. PMID 21455681 DOI: 10.1007/S12013-011-9183-7  0.64
2011 Toshchakov VY, Szmacinski H, Couture LA, Lakowicz JR, Vogel SN. Targeting TLR4 signaling by TLR4 Toll/IL-1 receptor domain-derived decoy peptides: identification of the TLR4 Toll/IL-1 receptor domain dimerization interface. Journal of Immunology (Baltimore, Md. : 1950). 186: 4819-27. PMID 21402890 DOI: 10.4049/Jimmunol.1002424  0.64
2011 Shirey KA, Nhu QM, Yim KC, Roberts ZJ, Teijaro JR, Farber DL, Blanco JC, Vogel SN. The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo. Journal of Leukocyte Biology. 89: 351-7. PMID 21084628 DOI: 10.1189/Jlb.0410216  0.64
2010 Perkins DJ, Qureshi N, Vogel SN. A Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination. Mbio. 1. PMID 20978539 DOI: 10.1128/Mbio.00239-10  0.64
2010 Brauer R, Wang LC, Woon ST, Bridewell DJ, Henare K, Malinger D, Palmer BD, Vogel SN, Kieda C, Tijono SM, Ching LM. Labeling of oxidizable proteins with a photoactivatable analog of the antitumor agent DMXAA: evidence for redox signaling in its mode of action. Neoplasia (New York, N.Y.). 12: 755-65. PMID 20824052 DOI: 10.1593/Neo.10636  0.64
2010 Blanco JC, Boukhvalova MS, Shirey KA, Prince GA, Vogel SN. New insights for development of a safe and protective RSV vaccine. Human Vaccines. 6: 482-92. PMID 20671419 DOI: 10.4161/Hv.6.6.11562  0.64
2010 Shirey KA, Pletneva LM, Puche AC, Keegan AD, Prince GA, Blanco JC, Vogel SN. Control of RSV-induced lung injury by alternatively activated macrophages is IL-4R alpha-, TLR4-, and IFN-beta-dependent. Mucosal Immunology. 3: 291-300. PMID 20404812 DOI: 10.1038/Mi.2010.6  0.64
2010 Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, Vanaja SK, Monks BG, Ganesan S, Latz E, Hornung V, Vogel SN, Szomolanyi-Tsuda E, Fitzgerald KA. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nature Immunology. 11: 395-402. PMID 20351692 DOI: 10.1038/Ni.1864  0.64
2010 Gao JJ, Shen J, Kolbert C, Raghavakaimal S, Papasian CJ, Qureshi AA, Vogel SN, Morrison DC, Qureshi N. The proteasome regulates bacterial CpG DNA-induced signaling pathways in murine macrophages. Shock (Augusta, Ga.). 34: 390-401. PMID 20160661 DOI: 10.1097/Shk.0B013E3181D884Ea  0.64
2010 Mohapatra SK, Cole LE, Evans C, Sobral BW, Bassaganya-Riera J, Hontecillas R, Vogel SN, Crasta OR. Modulation of hepatic PPAR expression during Ft LVS LPS-induced protection from Francisella tularensis LVS infection. Bmc Infectious Diseases. 10: 10. PMID 20082697 DOI: 10.1186/1471-2334-10-10  0.64
2010 Swisher JF, Burton N, Bacot SM, Vogel SN, Feldman GM. Annexin A2 tetramer activates human and murine macrophages through TLR4. Blood. 115: 549-58. PMID 19965653 DOI: 10.1182/Blood-2009-06-226944  0.64
2010 Cole LE, Laird MH, Seekatz A, Santiago A, Jiang Z, Barry E, Shirey KA, Fitzgerald KA, Vogel SN. Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling. Journal of Leukocyte Biology. 87: 275-81. PMID 19889726 DOI: 10.1189/Jlb.0909619  0.64
2010 Nhu QM, Shirey K, Teijaro JR, Farber DL, Netzel-Arnett S, Antalis TM, Fasano A, Vogel SN. Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo. Mucosal Immunology. 3: 29-39. PMID 19865078 DOI: 10.1038/Mi.2009.120  0.64
2010 Cooper ZA, Ghosh A, Gupta A, Maity T, Benjamin IJ, Vogel SN, Hasday JD, Singh IS. Febrile-range temperature modifies cytokine gene expression in LPS-stimulated macrophages by differentially modifying NF-{kappa}B recruitment to cytokine gene promoters. American Journal of Physiology. Cell Physiology. 298: C171-81. PMID 19846753 DOI: 10.1152/Ajpcell.00346.2009  0.64
2009 Tripathi A, Lammers KM, Goldblum S, Shea-Donohue T, Netzel-Arnett S, Buzza MS, Antalis TM, Vogel SN, Zhao A, Yang S, Arrietta MC, Meddings JB, Fasano A. Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2. Proceedings of the National Academy of Sciences of the United States of America. 106: 16799-804. PMID 19805376 DOI: 10.1073/Pnas.0906773106  0.64
2009 Green NM, Laws A, Kiefer K, Busconi L, Kim YM, Brinkmann MM, Trail EH, Yasuda K, Christensen SR, Shlomchik MJ, Vogel S, Connor JH, Ploegh H, Eilat D, Rifkin IR, et al. Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop. Journal of Immunology (Baltimore, Md. : 1950). 183: 1569-76. PMID 19587008 DOI: 10.4049/Jimmunol.0803899  0.64
2009 Santiago AE, Cole LE, Franco A, Vogel SN, Levine MM, Barry EM. Characterization of rationally attenuated Francisella tularensis vaccine strains that harbor deletions in the guaA and guaB genes. Vaccine. 27: 2426-36. PMID 19368784 DOI: 10.1016/J.Vaccine.2009.02.073  0.64
2009 Laird MH, Rhee SH, Perkins DJ, Medvedev AE, Piao W, Fenton MJ, Vogel SN. TLR4/MyD88/PI3K interactions regulate TLR4 signaling. Journal of Leukocyte Biology. 85: 966-77. PMID 19289601 DOI: 10.1189/Jlb.1208763  0.64
2009 Cole LE, Yang Y, Elkins KL, Fernandez ET, Qureshi N, Shlomchik MJ, Herzenberg LA, Herzenberg LA, Vogel SN. Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge. Proceedings of the National Academy of Sciences of the United States of America. 106: 4343-8. PMID 19251656 DOI: 10.1073/Pnas.0813411106  0.64
2008 Heller NM, Qi X, Junttila IS, Shirey KA, Vogel SN, Paul WE, Keegan AD. Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages. Science Signaling. 1: ra17. PMID 19109239 DOI: 10.1126/Scisignal.1164795  0.64
2008 Li XL, Ezelle HJ, Kang TJ, Zhang L, Shirey KA, Harro J, Hasday JD, Mohapatra SK, Crasta OR, Vogel SN, Cross AS, Hassel BA. An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity. Proceedings of the National Academy of Sciences of the United States of America. 105: 20816-21. PMID 19075243 DOI: 10.1073/Pnas.0807265105  0.64
2008 Harrison LM, Rallabhandi P, Michalski J, Zhou X, Steyert SR, Vogel SN, Kaper JB. Vibrio cholerae flagellins induce Toll-like receptor 5-mediated interleukin-8 production through mitogen-activated protein kinase and NF-kappaB activation. Infection and Immunity. 76: 5524-34. PMID 18809662 DOI: 10.1128/Iai.00843-08  0.64
2008 Reis J, Tan X, Yang R, Rockwell CE, Papasian CJ, Vogel SN, Morrison DC, Qureshi AA, Qureshi N. A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model. Innate Immunity. 14: 319-29. PMID 18809656 DOI: 10.1177/1753425908096855  0.64
2008 Shirey KA, Cole LE, Keegan AD, Vogel SN. Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism. Journal of Immunology (Baltimore, Md. : 1950). 181: 4159-67. PMID 18768873 DOI: 10.4049/Jimmunol.181.6.4159  0.64
2008 Shea-Donohue T, Thomas K, Cody MJ, Aiping Zhao, Detolla LJ, Kopydlowski KM, Fukata M, Lira SA, Vogel SN. Mice deficient in the CXCR2 ligand, CXCL1 (KC/GRO-alpha), exhibit increased susceptibility to dextran sodium sulfate (DSS)-induced colitis. Innate Immunity. 14: 117-24. PMID 18713728 DOI: 10.1177/1753425908088724  0.64
2008 Ashtekar AR, Zhang P, Katz J, Deivanayagam CC, Rallabhandi P, Vogel SN, Michalek SM. TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis. Journal of Leukocyte Biology. 84: 1434-46. PMID 18708593 DOI: 10.1189/Jlb.0308215  0.64
2008 Rallabhandi P, Nhu QM, Toshchakov VY, Piao W, Medvedev AE, Hollenberg MD, Fasano A, Vogel SN. Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity. The Journal of Biological Chemistry. 283: 24314-25. PMID 18622013 DOI: 10.1074/Jbc.M804800200  0.64
2008 Kang TJ, Basu S, Zhang L, Thomas KE, Vogel SN, Baillie L, Cross AS. Bacillus anthracis spores and lethal toxin induce IL-1beta via functionally distinct signaling pathways. European Journal of Immunology. 38: 1574-84. PMID 18493980 DOI: 10.1002/Eji.200838141  0.64
2008 Lammers KM, Lu R, Brownley J, Lu B, Gerard C, Thomas K, Rallabhandi P, Shea-Donohue T, Tamiz A, Alkan S, Netzel-Arnett S, Antalis T, Vogel SN, Fasano A. Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology. 135: 194-204.e3. PMID 18485912 DOI: 10.1053/J.Gastro.2008.03.023  0.64
2008 Cole LE, Santiago A, Barry E, Kang TJ, Shirey KA, Roberts ZJ, Elkins KL, Cross AS, Vogel SN. Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways. Journal of Immunology (Baltimore, Md. : 1950). 180: 6885-91. PMID 18453609 DOI: 10.4049/Jimmunol.180.10.6885  0.64
2008 Roberts ZJ, Ching LM, Vogel SN. IFN-beta-dependent inhibition of tumor growth by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 28: 133-9. PMID 18338946 DOI: 10.1089/Jir.2007.0992  0.64
2008 Gong P, Angelini DJ, Yang S, Xia G, Cross AS, Mann D, Bannerman DD, Vogel SN, Goldblum SE. TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia. The Journal of Biological Chemistry. 283: 13437-49. PMID 18326860 DOI: 10.1074/Jbc.M707986200  0.64
2008 Rallabhandi P, Awomoyi A, Thomas KE, Phalipon A, Fujimoto Y, Fukase K, Kusumoto S, Qureshi N, Sztein MB, Vogel SN. Differential activation of human TLR4 by Escherichia coli and Shigella flexneri 2a lipopolysaccharide: combined effects of lipid A acylation state and TLR4 polymorphisms on signaling. Journal of Immunology (Baltimore, Md. : 1950). 180: 1139-47. PMID 18178854 DOI: 10.4049/Jimmunol.180.2.1139  0.64
2007 Chen H, Cowan MJ, Hasday JD, Vogel SN, Medvedev AE. Tobacco smoking inhibits expression of proinflammatory cytokines and activation of IL-1R-associated kinase, p38, and NF-kappaB in alveolar macrophages stimulated with TLR2 and TLR4 agonists. Journal of Immunology (Baltimore, Md. : 1950). 179: 6097-106. PMID 17947684 DOI: 10.4049/Jimmunol.179.9.6097  0.64
2007 Perkins DJ, Gray MC, Hewlett EL, Vogel SN. Bordetella pertussis adenylate cyclase toxin (ACT) induces cyclooxygenase-2 (COX-2) in murine macrophages and is facilitated by ACT interaction with CD11b/CD18 (Mac-1). Molecular Microbiology. 66: 1003-15. PMID 17927697 DOI: 10.1111/J.1365-2958.2007.05972.X  0.64
2007 Bafica A, Feng CG, Santiago HC, Aliberti J, Cheever A, Thomas KE, Taylor GA, Vogel SN, Sher A. The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflammatory cytokine production and prevents endotoxemia. Journal of Immunology (Baltimore, Md. : 1950). 179: 5514-22. PMID 17911638 DOI: 10.4049/Jimmunol.179.8.5514  0.64
2007 Awomoyi AA, Rallabhandi P, Pollin TI, Lorenz E, Sztein MB, Boukhvalova MS, Hemming VG, Blanco JC, Vogel SN. Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children. Journal of Immunology (Baltimore, Md. : 1950). 179: 3171-7. PMID 17709532 DOI: 10.4049/Jimmunol.179.5.3171  0.64
2007 Toshchakov VY, Vogel SN. Cell-penetrating TIR BB loop decoy peptides a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions. Expert Opinion On Biological Therapy. 7: 1035-50. PMID 17665992 DOI: 10.1517/14712598.7.7.1035  0.64
2007 Antalis TM, Shea-Donohue T, Vogel SN, Sears C, Fasano A. Mechanisms of disease: protease functions in intestinal mucosal pathobiology. Nature Clinical Practice. Gastroenterology & Hepatology. 4: 393-402. PMID 17607295 DOI: 10.1038/Ncpgasthep0846  0.64
2007 Polumuri SK, Toshchakov VY, Vogel SN. Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fc gamma receptor ligation in murine macrophages. Journal of Immunology (Baltimore, Md. : 1950). 179: 236-46. PMID 17579043 DOI: 10.4049/Jimmunol.179.1.236  0.64
2007 Roberts ZJ, Goutagny N, Perera PY, Kato H, Kumar H, Kawai T, Akira S, Savan R, van Echo D, Fitzgerald KA, Young HA, Ching LM, Vogel SN. The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis. The Journal of Experimental Medicine. 204: 1559-69. PMID 17562815 DOI: 10.1084/Jem.20061845  0.64
2007 Cole LE, Shirey KA, Barry E, Santiago A, Rallabhandi P, Elkins KL, Puche AC, Michalek SM, Vogel SN. Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages. Infection and Immunity. 75: 4127-37. PMID 17517865 DOI: 10.1128/Iai.01868-06  0.64
2007 Medvedev AE, Piao W, Shoenfelt J, Rhee SH, Chen H, Basu S, Wahl LM, Fenton MJ, Vogel SN. Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance. The Journal of Biological Chemistry. 282: 16042-53. PMID 17392283 DOI: 10.1074/Jbc.M606781200  0.64
2007 Cuesta N, Nhu QM, Zudaire E, Polumuri S, Cuttitta F, Vogel SN. IFN regulatory factor-2 regulates macrophage apoptosis through a STAT1/3- and caspase-1-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 178: 3602-11. PMID 17339457 DOI: 10.4049/Jimmunol.178.6.3602  0.64
2007 Toshchakov VY, Fenton MJ, Vogel SN. Cutting Edge: Differential inhibition of TLR signaling pathways by cell-permeable peptides representing BB loops of TLRs. Journal of Immunology (Baltimore, Md. : 1950). 178: 2655-60. PMID 17312106 DOI: 10.4049/Jimmunol.178.5.2655  0.64
2007 Sabroe I, Dockrell DH, Vogel SN, Renshaw SA, Whyte MK, Dower SK. Identifying and hurdling obstacles to translational research. Nature Reviews. Immunology. 7: 77-82. PMID 17186032 DOI: 10.1038/Nri1999  0.64
2007 Weaver LK, Pioli PA, Wardwell K, Vogel SN, Guyre PM. Up-regulation of human monocyte CD163 upon activation of cell-surface Toll-like receptors. Journal of Leukocyte Biology. 81: 663-71. PMID 17164428 DOI: 10.1189/Jlb.0706428  0.64
2006 Nhu QM, Cuesta N, Vogel SN. Transcriptional regulation of lipopolysaccharide (LPS)-induced Toll-like receptor (TLR) expression in murine macrophages: role of interferon regulatory factors 1 (IRF-1) and 2 (IRF-2). Journal of Endotoxin Research. 12: 285-95. PMID 17059692 DOI: 10.1177/09680519060120050401  0.64
2006 Joshi VD, Kalvakolanu DV, Chen W, Zhang L, Kang TJ, Thomas KE, Vogel SN, Cross AS. A role for Stat1 in the regulation of lipopolysaccharide-induced interleukin-1beta expression. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 739-47. PMID 17032168 DOI: 10.1089/Jir.2006.26.739  0.64
2006 Thomas KE, Galligan CL, Newman RD, Fish EN, Vogel SN. Contribution of interferon-beta to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide. The Journal of Biological Chemistry. 281: 31119-30. PMID 16912041 DOI: 10.1074/Jbc.M604958200  0.64
2006 Weaver LK, Hintz-Goldstein KA, Pioli PA, Wardwell K, Qureshi N, Vogel SN, Guyre PM. Pivotal advance: activation of cell surface Toll-like receptors causes shedding of the hemoglobin scavenger receptor CD163. Journal of Leukocyte Biology. 80: 26-35. PMID 16799153 DOI: 10.1189/Jlb.1205756  0.64
2006 Rallabhandi P, Bell J, Boukhvalova MS, Medvedev A, Lorenz E, Arditi M, Hemming VG, Blanco JC, Segal DM, Vogel SN. Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling. Journal of Immunology (Baltimore, Md. : 1950). 177: 322-32. PMID 16785528 DOI: 10.4049/Jimmunol.177.1.322  0.64
2006 Shen J, Gao JJ, Zhang G, Tan X, Morrison DC, Papasian C, Vogel SN, Qureshi N. Proteasome-mediated regulation of CpG DNA- and peptidoglycan-induced cytokines, inflammatory genes, and mitogen-activated protein kinase activation. Shock (Augusta, Ga.). 25: 594-9. PMID 16721267 DOI: 10.1097/01.Shk.0000209555.46704.2D  0.64
2006 Medvedev AE, Sabroe I, Hasday JD, Vogel SN. Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease. Journal of Endotoxin Research. 12: 133-50. PMID 16719986 DOI: 10.1179/096805106X102255  0.64
2006 Cole LE, Elkins KL, Michalek SM, Qureshi N, Eaton LJ, Rallabhandi P, Cuesta N, Vogel SN. Immunologic consequences of Francisella tularensis live vaccine strain infection: role of the innate immune response in infection and immunity. Journal of Immunology (Baltimore, Md. : 1950). 176: 6888-99. PMID 16709849 DOI: 10.4049/Jimmunol.176.11.6888  0.64
2006 Shen J, Reis J, Morrison DC, Papasian C, Raghavakaimal S, Kolbert C, Qureshi AA, Vogel SN, Qureshi N. Key inflammatory signaling pathways are regulated by the proteasome. Shock (Augusta, Ga.). 25: 472-84. PMID 16680012 DOI: 10.1097/01.Shk.0000209554.46704.64  0.64
2006 Boukhvalova MS, Prince GA, Soroush L, Harrigan DC, Vogel SN, Blanco JC. The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease. Vaccine. 24: 5027-35. PMID 16675071 DOI: 10.1016/J.Vaccine.2006.03.064  0.64
2006 Katz J, Zhang P, Martin M, Vogel SN, Michalek SM. Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS. Infection and Immunity. 74: 2809-16. PMID 16622218 DOI: 10.1128/Iai.74.5.2809-2816.2006  0.64
2006 Thomas KE, Sapone A, Fasano A, Vogel SN. Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac disease. Journal of Immunology (Baltimore, Md. : 1950). 176: 2512-21. PMID 16456012 DOI: 10.4049/Jimmunol.176.4.2512  0.64
2005 Politis AD, Vogel SN. Measurement of Fc gamma receptor-mediated binding and phagocytosis. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 14.8. PMID 18432943 DOI: 10.1002/0471142735.Im1408S68  0.64
2005 Divanovic S, Trompette A, Atabani SF, Madan R, Golenbock DT, Visintin A, Finberg RW, Tarakhovsky A, Vogel SN, Belkaid Y, Kurt-Jones EA, Karp CL. Inhibition of TLR-4/MD-2 signaling by RP105/MD-1. Journal of Endotoxin Research. 11: 363-8. PMID 16303092 DOI: 10.1177/09680519050110061201  0.64
2005 Vogel SN, Awomoyi AA, Rallabhandi P, Medvedev AE. Mutations in TLR4 signaling that lead to increased susceptibility to infection in humans: an overview. Journal of Endotoxin Research. 11: 333-9. PMID 16303088 DOI: 10.1177/09680519050110060801  0.64
2005 Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, Kurtz S, Coffield VM, Accavitti-Loper MA, Su L, Vogel SN, Braunstein M, Ting JP. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. The Journal of Biological Chemistry. 280: 39914-24. PMID 16203735 DOI: 10.1074/Jbc.M502820200  0.64
2005 Toshchakov VU, Basu S, Fenton MJ, Vogel SN. Differential involvement of BB loops of toll-IL-1 resistance (TIR) domain-containing adapter proteins in TLR4- versus TLR2-mediated signal transduction. Journal of Immunology (Baltimore, Md. : 1950). 175: 494-500. PMID 15972684 DOI: 10.4049/Jimmunol.175.1.494  0.64
2005 Medvedev AE, Thomas K, Awomoyi A, Kuhns DB, Gallin JI, Li X, Vogel SN. Cutting edge: expression of IL-1 receptor-associated kinase-4 (IRAK-4) proteins with mutations identified in a patient with recurrent bacterial infections alters normal IRAK-4 interaction with components of the IL-1 receptor complex. Journal of Immunology (Baltimore, Md. : 1950). 174: 6587-91. PMID 15905496 DOI: 10.4049/Jimmunol.174.11.6587  0.64
2005 Qureshi N, Vogel SN, Van Way C, Papasian CJ, Qureshi AA, Morrison DC. The proteasome: a central regulator of inflammation and macrophage function. Immunologic Research. 31: 243-60. PMID 15888915 DOI: 10.1385/Ir:31:3:243  0.64
2005 Divanovic S, Trompette A, Atabani SF, Madan R, Golenbock DT, Visintin A, Finberg RW, Tarakhovsky A, Vogel SN, Belkaid Y, Kurt-Jones EA, Karp CL. Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nature Immunology. 6: 571-8. PMID 15852007 DOI: 10.1038/Ni1198  0.64
2005 Richardson JY, Ottolini MG, Pletneva L, Boukhvalova M, Zhang S, Vogel SN, Prince GA, Blanco JC. Respiratory syncytial virus (RSV) infection induces cyclooxygenase 2: a potential target for RSV therapy. Journal of Immunology (Baltimore, Md. : 1950). 174: 4356-64. PMID 15778400 DOI: 10.4049/Jimmunol.174.7.4356  0.64
2005 Lentschat A, Karahashi H, Michelsen KS, Thomas LS, Zhang W, Vogel SN, Arditi M. Mastoparan, a G protein agonist peptide, differentially modulates TLR4- and TLR2-mediated signaling in human endothelial cells and murine macrophages. Journal of Immunology (Baltimore, Md. : 1950). 174: 4252-61. PMID 15778388 DOI: 10.4049/Jimmunol.174.7.4252  0.64
2004 Parker LC, Whyte MKB, Vogel SN, Dower SK, Sabroe I. Toll-Like Receptor (TLR)2 and TLR4 Agonists Regulate CCR Expression in Human Monocytic Cells Journal of Immunology. 172: 4977-4986. PMID 15067079 DOI: 10.4049/Jimmunol.172.8.4977  0.64
2003 Vogel SN, Fitzgerald KA, Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Molecular Interventions. 3: 466-77. PMID 14993454 DOI: 10.1124/Mi.3.8.466  0.64
2003 Kozlov SV, Dobrovolskaia MA, Rice NR, Stewart CL, Vogel SN. A novel cell-based system for the rapid quantitative evaluation of (anti)-inflammatory potential of test substances. Journal of Immunological Methods. 281: 51-63. PMID 14580881 DOI: 10.1016/S0022-1759(03)00272-2  0.64
2003 Gao JJ, Diesl V, Wittmann T, Morrison DC, Ryan JL, Vogel SN, Follettie MT. Bacterial LPS and CpG DNA differentially induce gene expression profiles in mouse macrophages Journal of Endotoxin Research. 9: 237-243. PMID 12935354 DOI: 10.1179/096805103225001431  0.64
2003 Sabroe I, Read RC, Whyte MKB, Dockrell DH, Vogel SN, Dower SK. Toll-like receptors in health and disease: Complex questions remain Journal of Immunology. 171: 1630-1635. PMID 12902458 DOI: 10.4049/Jimmunol.171.4.1630  0.64
2003 Heldwein KA, Liang MD, Andresen TK, Thomas KE, Marty AM, Cuesta N, Vogel SN, Fenton MJ. TLR2 and TLR4 serve distinct roles in the host immune response against Mycobacterium bovis BCG. Journal of Leukocyte Biology. 74: 277-86. PMID 12885945 DOI: 10.1189/Jlb.0103026  0.64
2003 Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons GJ, Leibovich SJ. An angiogenic switch in macrophages involving synergy between toll-like receptors 2, 4, 7, and 9 and adenosine A2A receptors American Journal of Pathology. 163: 711-721. PMID 12875990 DOI: 10.1016/S0002-9440(10)63698-X  0.64
2003 Qureshi N, Perera PY, Shen J, Zhang G, Lenschat A, Splitter G, Morrison DC, Vogel SN. The proteasome as a lipopolysaccharide-binding protein in macrophages: Differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events Journal of Immunology. 171: 1515-1525. PMID 12874245 DOI: 10.4049/Jimmunol.171.3.1515  0.64
2003 Martin M, Schifferle RE, Cuesta N, Vogel SN, Katz J, Michalek SM. Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 171: 717-25. PMID 12847238 DOI: 10.4049/Jimmunol.171.2.717  0.64
2003 Toshchakov V, Jones BW, Lentschat A, Silva A, Perera PY, Thomas K, Cody MJ, Zhang S, Williams BR, Major J, Hamilton TA, Fenton MJ, Vogel SN. TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: interferon-beta-dependent signaling in TLR4-mediated responses. Journal of Endotoxin Research. 9: 169-75. PMID 12831458 DOI: 10.1179/096805103125001577  0.64
2003 Chen Y, Hallenbeck JM, Ruetzler C, Bol D, Thomas K, Berman NE, Vogel SN. Overexpression of monocyte chemoattractant protein 1 in the brain exacerbates ischemic brain injury and is associated with recruitment of inflammatory cells. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 748-55. PMID 12796723 DOI: 10.1097/01.Wcb.0000071885.63724.20  0.64
2003 Vogel SN, Fenton M. Toll-like receptor 4 signalling: New perspectives on a complex signal-transduction problem Biochemical Society Transactions. 31: 664-668. PMID 12773178 DOI: 10.1042/BST0310664  0.64
2003 Cuesta N, Salkowski CA, Thomas KE, Vogel SN. Regulation of lipopolysaccharide sensitivity by IFN regulatory factor-2. Journal of Immunology (Baltimore, Md. : 1950). 170: 5739-47. PMID 12759457 DOI: 10.4049/Jimmunol.170.11.5739  0.64
2003 Sabroe I, Prince LR, Jones EC, Horsburgh MJ, Foster SJ, Vogel SN, Dower SK, Whyte MKB. Selective roles for Toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span Journal of Immunology. 170: 5268-5275. PMID 12734376 DOI: 10.4049/Jimmunol.170.10.5268  0.64
2003 Medvedev AE, Vogel SN. Overexpression of CD14, TLR4, and MD-2 in HEK 293T cells does not prevent induction of in vitro endotoxin tolerance Journal of Endotoxin Research. 9: 60-64. PMID 12691621 DOI: 10.1179/096805103125001360  0.64
2003 Rhee SH, Jones BW, Toshchakov V, Vogel SN, Fenton MJ. Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages. The Journal of Biological Chemistry. 278: 22506-12. PMID 12686553 DOI: 10.1074/Jbc.M208633200  0.64
2003 Zhou X, Girón JA, Torres AG, Crawford JA, Negrete E, Vogel SN, Kaper JB. Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cells. Infection and Immunity. 71: 2120-9. PMID 12654834 DOI: 10.1128/Iai.71.4.2120-2129.2003  0.64
2003 Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN. Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components. Journal of Immunology (Baltimore, Md. : 1950). 170: 508-19. PMID 12496438 DOI: 10.4049/Jimmunol.170.1.508  0.64
2002 Bradford M, Schroeder AJ, Morse HC, Vogel SN, Cowdery JS. CpG DNA induced IL-12 p40 gene activation is independent of STAT1 activation or production of interferon consensus sequence binding protein Journal of Biomedical Science. 9: 688-696. PMID 12432235 DOI: 10.1159/000067280  0.64
2002 Schilling D, Thomas K, Nixdorff K, Vogel SN, Fenton MJ. Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 169: 5874-80. PMID 12421970 DOI: 10.4049/Jimmunol.169.10.5874  0.64
2002 Medvedev AE, Lentschat A, Wahl LM, Golenbock DT, Vogel SN. Dysregulation of LPS-induced toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells Journal of Immunology. 169: 5209-5216. PMID 12391239 DOI: 10.4049/Jimmunol.169.9.5209  0.64
2002 Dobrovolskaia MA, Vogel SN. Toll receptors, CD14, and macrophage activation and deactivation by LPS Microbes and Infection. 4: 903-914. PMID 12106783 DOI: 10.1016/S1286-4579(02)01613-1  0.64
2002 Rajnik M, Salkowski CA, Thomas KE, Li YY, Rollwagen FM, Vogel SN. Induction of early inflammatory gene expression in a murine model of nonresuscitated, fixed-volume hemorrhage. Shock (Augusta, Ga.). 17: 322-8. PMID 11954835 DOI: 10.1097/00024382-200204000-00015  0.64
2002 Toshchakov V, Jones BW, Perera PY, Thomas K, Cody MJ, Zhang S, Williams BR, Major J, Hamilton TA, Fenton MJ, Vogel SN. TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages. Nature Immunology. 3: 392-8. PMID 11896392 DOI: 10.1038/Ni774  0.64
2002 Sebastiani G, Blais V, Sancho V, Vogel SN, Stevenson MM, Gros P, Lapointe JM, Rivest S, Malo D. Host immune response to Salmonella enterica serovar Typhimurium infection in mice derived from wild strains. Infection and Immunity. 70: 1997-2009. PMID 11895964 DOI: 10.1128/IAI.70.4.1997-2009.2002  0.64
2001 Vogel SN, Friedman RM, Hogan MM. Measurement of antiviral activity induced by interferons alpha, beta, and gamma. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 6.9. PMID 18432822 DOI: 10.1002/0471142735.Im0609S37  0.64
2001 Vogel S, Hirschfeld MJ, Perera PY. Signal integration in lipopolysaccharide (LPS)-stimulated murine macrophages Journal of Endotoxin Research. 7: 237-241. PMID 11581577 DOI: 10.1177/09680519010070030801  0.64
2001 Means TK, Jones BW, Schromm AB, Shurtleff BA, Smith JA, Keane J, Golenbock DT, Vogel SN, Fenton MJ. Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses. Journal of Immunology (Baltimore, Md. : 1950). 166: 4074-82. PMID 11238656 DOI: 10.4049/Jimmunol.166.6.4074  0.64
2001 Hirschfeld M, Weis JJ, Toshchakov V, Salkowski CA, Cody MJ, Ward DC, Qureshi N, Michalek SM, Vogel SN. Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infection and Immunity. 69: 1477-82. PMID 11179315 DOI: 10.1128/Iai.69.3.1477-1482.2001  0.64
2000 Salkowski CA, Thomas KE, Cody MJ, Vogel SN. Impaired IFN-gamma production in IFN regulatory factor-1 knockout mice during endotoxemia is secondary to a loss of both IL-12 and IL-12 receptor expression. Journal of Immunology (Baltimore, Md. : 1950). 165: 3970-7. PMID 11034406 DOI: 10.4049/Jimmunol.165.7.3970  0.64
2000 Hirschfeld M, Ma Y, Weis JH, Vogel SN, Weis JJ. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. Journal of Immunology (Baltimore, Md. : 1950). 165: 618-22. PMID 10878331 DOI: 10.4049/Jimmunol.165.2.618  0.64
1999 Seth P, Mani H, Singh AK, Banaudha KK, Madhavan S, Sidhu GS, Gaddipati JP, Vogel SN, Maheshwari RK. Acceleration of viral replication and up-regulation of cytokine levels by antimalarials: implications in malaria-endemic areas. The American Journal of Tropical Medicine and Hygiene. 61: 180-6. PMID 10463664 DOI: 10.4269/Ajtmh.1999.61.180  0.64
1999 Grieder FB, Vogel SN. Role of interferon and interferon regulatory factors in early protection against Venezuelan equine encephalitis virus infection Virology. 257: 106-118. PMID 10208925 DOI: 10.1006/Viro.1999.9662  0.64
1999 Iadecola C, Salkowski CA, Zhang F, Aber T, Nagayama M, Vogel SN, Ross ME. The transcription factor interferon regulatory factor 1 is expressed after cerebral ischemia and contributes to ischemic brain injury Journal of Experimental Medicine. 189: 719-727. PMID 9989987 DOI: 10.1084/Jem.189.4.719  0.64
1999 Perera PY, Kadow JF, Fairchild CR, Johnston KA, Vogel SN. Analysis of structure activity relationships for LPS-mimetic activities of taxane analogs in murine macrophages Journal of Endotoxin Research. 5: 261-267. DOI: 10.1177/09680519990050050201  0.64
1998 Poltorak A, Smirnova I, He X, Liu MY, Van Huffel C, McNally O, Birdwell D, Alejos E, Silva M, Du X, Thompson P, Chan EK, Ledesma J, Roe B, Clifton S, ... Vogel SN, et al. Genetic and physical mapping of the Lps locus: identification of the toll-4 receptor as a candidate gene in the critical region. Blood Cells, Molecules & Diseases. 24: 340-55. PMID 10087992 DOI: 10.1006/Bcmd.1998.0201  0.64
1998 Zaks-Zilberman M, Salkowski CA, Elsasser T, Cuttitta F, Vogel SN. Induction of adrenomedullin mRNA and protein by lipopolysaccharide and paclitaxel (Taxol) in murine macrophages. Infection and Immunity. 66: 4669-75. PMID 9746563 DOI: 10.1128/Iai.66.10.4669-4675.1998  0.48
1998 Perera PY, Qureshi N, Christ WJ, Stütz P, Vogel SN. Lipopolysaccharide and its analog antagonists display differential serum factor dependencies for induction of cytokine genes in murine macrophages. Infection and Immunity. 66: 2562-9. PMID 9596717 DOI: 10.1128/Iai.66.6.2562-2569.1998  0.64
1996 Barber SA, Detore G, McNally R, Vogel SN. Stimulation of the ceramide pathway partially mimics lipopolysaccharide-induced responses in murine peritoneal macrophages Infection and Immunity. 64: 3397-3400. PMID 8757882 DOI: 10.1128/Iai.64.8.3397-3400.1996  0.64
1996 Grunvald E, Chiaramonte M, Hieny S, Wysocka M, Trinchieri G, Vogel SN, Gazzinelli RT, Sher A. Biochemical characterization and protein kinase C dependency of monokine-inducing activities of Toxoplasma gondii. Infection and Immunity. 64: 2010-8. PMID 8675301 DOI: 10.1128/Iai.64.6.2010-2018.1996  0.64
1996 Barber SA, Salkowski CA, Fultz MJ, Perera PY, McNally R, Vogel SN. Regulation of gene expression and nitric oxide production in murine macrophages by the serine/threonine phosphatase inhibitor okadaic acid Journal of Endotoxin Research. 3: 19-27. DOI: 10.1177/096805199600300103  0.64
1995 Barber SA, Fultz MJ, Salkowski CA, Vogel SN. Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages Infection and Immunity. 63: 601-608. PMID 7822029 DOI: 10.1128/Iai.63.2.601-608.1995  0.64
1995 Morrissey PJ, Charrier K, Vogel SN. Exogenous tumor necrosis factor alpha and interleukin-1α increase resistance to Salmonella typhimurium: Efficacy is influenced by the Ity and Lps loci Infection and Immunity. 63: 3196-3198. PMID 7622247 DOI: 10.1128/iai.63.8.3196-3198.1995  0.64
1994 Bovolenta C, Driggers PH, Marks MS, Medin JA, Politis AD, Vogel SN, Levy DE, Sakaguchi K, Appella E, Coligan JE. Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family. Proceedings of the National Academy of Sciences of the United States of America. 91: 5046-50. PMID 8197182 DOI: 10.1073/Pnas.91.11.5046  0.64
1993 Henricson BE, Manthey CL, Perera PY, Hamilton TA, Vogel SN. Dissociation of lipopolysaccharide (LPS)-inducible gene expression in murine macrophages pretreated with smooth LPS versus monophosphoryl lipid A Infection and Immunity. 61: 2325-2333. PMID 8388859 DOI: 10.1128/Iai.61.6.2325-2333.1993  0.64
1992 Neta R, Perlstein R, Vogel SN, David Ledney G, Abrams J. Role of interleukin 6 (IL-6) in protection from lethal irradiation and in endocrine responses to IL-1 and tumor necrosis factor Journal of Experimental Medicine. 175: 689-694. PMID 1311016 DOI: 10.1084/jem.175.3.689  0.64
1991 Vogel SN, Henricson BE, Neta R. Roles of interleukin-1 and tumor necrosis factor in lipopolysaccharide-induced hypoglycemia Infection and Immunity. 59: 2494-2498. PMID 1828792 DOI: 10.1128/Iai.59.7.2494-2498.1991  0.64
1991 Henricson BE, Neta R, Vogel SN. An interleukin-1 receptor antagonist blocks lipopolysaccharide-induced colony-stimulating factor production and early endotoxin tolerance Infection and Immunity. 59: 1188-1191. PMID 1825485 DOI: 10.1128/Iai.59.3.1188-1191.1991  0.64
1989 Hogan MM, Yancey KB, Vogel SN. Role of C5a in the induction of tumoricidal activity in C3H/HeJ (Lps(d)) and C3H/OuJ (Lps(n)) macrophages Journal of Leukocyte Biology. 46: 565-570. PMID 2509612 DOI: 10.1002/Jlb.46.6.565  0.64
1988 Vogel SN, Kaufman EN, Tate MD, Neta R. Recombinant interleukin-1α and recombinant tumor necrosis factor α synergize in vivo to induce early endotoxin tolerance and associated hematopoietic changes Infection and Immunity. 56: 2650-2657. PMID 3262089 DOI: 10.1128/Iai.56.10.2650-2657.1988  0.64
1986 Madonna GS, Peterson JE, Ribi EE, Vogel SN. Early-phase endotoxin tolerance: induction by a detoxified lipid A derivative, monophosphoryl lipid A. Infection and Immunity. 52: 6-11. PMID 3514464 DOI: 10.1128/iai.52.1.6-11.1986  0.64
1983 Connolly KM, Elgert KD, Conroy JM, Vogel SN, Rutherford RB. Immunoregulation of the mixed lymphocyte reaction by macrophage-derived factors: functional and biochemical separation of enhancing and inhibitory factors. Immunobiology. 164: 144-59. PMID 6221994 DOI: 10.1016/S0171-2985(83)80006-0  0.64
1983 Vogel SN, English KE, Fertsch D, Fultz MJ. Differential modulation of macrophage membrane markers by interferon: Analysis of Fc and C3b receptors, Mac-1 and Ia antigen expression Journal of Interferon Research. 3: 153-160. PMID 6192184 DOI: 10.1089/Jir.1983.3.153  0.64
1982 Vogel SN, English KE, O'Brien AD. Silica enhancement of murine endotoxin sensitivity Infection and Immunity. 38: 681-685. PMID 6183219 DOI: 10.1128/iai.38.2.681-685.1982  0.64
1981 Sztein MB, Vogel SN, Sipe JD, Murphy PA, Mizel SB, Oppenheim JJ, Rosenstreich DL. The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen Cellular Immunology. 63: 164-176. PMID 6791836 DOI: 10.1016/0008-8749(81)90037-X  0.64
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