| Year |
Citation |
Score |
| 2022 |
Taylor JA, Hutchinson MA, Gearhart PJ, Maul RW. Antibodies in action: the role of humoral immunity in the fight against atherosclerosis. Immunity & Ageing : I & A. 19: 59. PMID 36461105 DOI: 10.1186/s12979-022-00316-6 |
0.432 |
|
| 2021 |
Hutchinson MA, Park HS, Zanotti KJ, Alvarez-Gonzalez J, Zhang J, Zhang L, Telljohann R, Wang M, Lakatta EG, Gearhart PJ, Maul RW. Auto-Antibody Production During Experimental Atherosclerosis in Mice. Frontiers in Immunology. 12: 695220. PMID 34305930 DOI: 10.3389/fimmu.2021.695220 |
0.334 |
|
| 2021 |
Alvarez-Gonzalez J, Yasgar A, Maul RW, Rieffer AE, Crawford DJ, Salamango DJ, Dorjsuren D, Zakharov AV, Jansen DJ, Rai G, Marugan J, Simeonov A, Harris RS, Kohli RM, Gearhart PJ. Small Molecule Inhibitors of Activation-Induced Deaminase Decrease Class Switch Recombination in B Cells. Acs Pharmacology & Translational Science. 4: 1214-1226. PMID 34151211 DOI: 10.1021/acsptsci.1c00064 |
0.387 |
|
| 2021 |
Maul RW, Catalina MD, Kumar V, Bachali P, Grammer AC, Wang S, Yang W, Hasni S, Ettinger R, Lipsky PE, Gearhart PJ. Transcriptome and IgH Repertoire Analyses Show That CD11c B Cells Are a Distinct Population With Similarity to B Cells Arising in Autoimmunity and Infection. Frontiers in Immunology. 12: 649458. PMID 33815408 DOI: 10.3389/fimmu.2021.649458 |
0.417 |
|
| 2019 |
Russell Knode LM, Park HS, Maul RW, Gearhart PJ. B cells from young and old mice switch isotypes with equal frequencies after ex vivo stimulation. Cellular Immunology. 103966. PMID 31447053 DOI: 10.1016/J.Cellimm.2019.103966 |
0.402 |
|
| 2018 |
Jones BG, Sealy RE, Penkert RR, Surman SL, Maul RW, Neale G, Xu B, Gearhart PJ, Hurwitz JL. Complex sex-biased antibody responses: Estrogen receptors bind estrogen response elements centered within immunoglobulin heavy chain gene enhancers. International Immunology. PMID 30407507 DOI: 10.1093/Intimm/Dxy074 |
0.312 |
|
| 2018 |
Pape KA, Maul RW, Dileepan T, Paustian AS, Gearhart PJ, Jenkins MK. Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM and Transient IgG Memory B Cells. Immunity. PMID 29884459 DOI: 10.1016/J.Immuni.2018.04.019 |
0.389 |
|
| 2018 |
Castiblanco DP, Norton DD, Maul RW, Gearhart PJ. J6 downstream intronic sequence is dispensable for RNA polymerase II accumulation and somatic hypermutation of the variable gene in Ramos cells. Molecular Immunology. 97: 101-108. PMID 29625296 DOI: 10.1016/J.Molimm.2018.03.031 |
0.311 |
|
| 2018 |
Gearhart PJ, Mock BA, Casellas R, Cancro MP. The Reign of Antibodies: A Celebration of and Tribute to Michael Potter and His Homogeneous Immunoglobulin Workshops. Journal of Immunology (Baltimore, Md. : 1950). 200: 23-26. PMID 29255086 DOI: 10.4049/Jimmunol.1701516 |
0.626 |
|
| 2017 |
Castiblanco DP, Maul RW, Russell Knode LM, Gearhart PJ. Co-Stimulation of BCR and Toll-Like Receptor 7 Increases Somatic Hypermutation, Memory B Cell Formation, and Secondary Antibody Response to Protein Antigen. Frontiers in Immunology. 8: 1833. PMID 29312329 DOI: 10.3389/Fimmu.2017.01833 |
0.425 |
|
| 2017 |
Myles A, Gearhart PJ, Cancro MP. Signals that drive T-bet expression in B cells. Cellular Immunology. PMID 28923237 DOI: 10.1016/J.Cellimm.2017.09.004 |
0.688 |
|
| 2017 |
Russell Knode LM, Naradikian MS, Myles A, Scholz JL, Hao Y, Liu D, Ford ML, Tobias JW, Cancro MP, Gearhart PJ. Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation. Journal of Immunology (Baltimore, Md. : 1950). PMID 28093524 DOI: 10.4049/Jimmunol.1601106 |
0.708 |
|
| 2016 |
Jones BG, Penkert RR, Xu B, Fan Y, Neale G, Gearhart PJ, Hurwitz JL. Binding of estrogen receptors to switch sites and regulatory elements in the immunoglobulin heavy chain locus of activated B cells suggests a direct influence of estrogen on antibody expression. Molecular Immunology. 77: 97-102. PMID 27494228 DOI: 10.1016/J.Molimm.2016.07.015 |
0.335 |
|
| 2016 |
Zanotti KJ, Gearhart PJ. Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases. Dna Repair. 38: 110-6. PMID 26719140 DOI: 10.1016/J.Dnarep.2015.11.011 |
0.389 |
|
| 2015 |
Gearhart PJ, Castiblanco DP, Russell Knode LM. Exceptional Antibodies Produced by Successive Immunizations. Plos Biology. 13: e1002321. PMID 26641938 DOI: 10.1371/journal.pbio.1002321 |
0.414 |
|
| 2015 |
Hathcock KS, Padilla-Nash HM, Camps J, Shin DM, Triner D, Shaffer AL, Maul RW, Steinberg SM, Gearhart PJ, Staudt LM, Morse HC, Ried T, Hodes RJ. ATM deficiency in absence of T cells promotes development of NF-kB-dependent murine B cell lymphomas that resemble human ABC DLBCL. Blood. PMID 26400962 DOI: 10.1182/Blood-2015-06-654749 |
0.401 |
|
| 2015 |
Maul RW, Saribasak H, Cao Z, Gearhart PJ. Topoisomerase I deficiency causes RNA polymerase II accumulation and increases AID abundance in immunoglobulin variable genes. Dna Repair. 30: 46-52. PMID 25869824 DOI: 10.1016/J.Dnarep.2015.03.004 |
0.314 |
|
| 2015 |
Zanotti KJ, Maul RW, Castiblanco DP, Yang W, Choi YJ, Fox JT, Myung K, Saribasak H, Gearhart PJ. ATAD5 deficiency decreases B cell division and Igh recombination. Journal of Immunology (Baltimore, Md. : 1950). 194: 35-42. PMID 25404367 DOI: 10.4049/Jimmunol.1401158 |
0.438 |
|
| 2014 |
Maul RW, Cao Z, Venkataraman L, Giorgetti CA, Press JL, Denizot Y, Du H, Sen R, Gearhart PJ. Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cells. The Journal of Experimental Medicine. 211: 2297-306. PMID 25288395 DOI: 10.1084/Jem.20131512 |
0.72 |
|
| 2014 |
Maul RW, Gearhart PJ. Refining the Neuberger model: Uracil processing by activated B cells. European Journal of Immunology. 44: 1913-6. PMID 24920531 DOI: 10.1002/Eji.201444813 |
0.414 |
|
| 2014 |
Gearhart PJ, Kelsoe G. A tribute to Michael S. Neuberger. The Journal of Clinical Investigation. 124: 3-5. PMID 24382382 DOI: 10.1172/Jci74366 |
0.456 |
|
| 2011 |
Saribasak H, Maul RW, Cao Z, McClure RL, Yang W, McNeill DR, Wilson DM, Gearhart PJ. XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes. The Journal of Experimental Medicine. 208: 2209-16. PMID 21967769 DOI: 10.1084/Jem.20111135 |
0.357 |
|
| 2011 |
Pape KA, Taylor JJ, Maul RW, Gearhart PJ, Jenkins MK. Different B cell populations mediate early and late memory during an endogenous immune response. Science (New York, N.Y.). 331: 1203-7. PMID 21310965 DOI: 10.1126/Science.1201730 |
0.331 |
|
| 2010 |
Maul RW, Gearhart PJ. AID and somatic hypermutation. Advances in Immunology. 105: 159-91. PMID 20510733 DOI: 10.1016/S0065-2776(10)05006-6 |
0.386 |
|
| 2010 |
Maul RW, Gearhart PJ. Controlling somatic hypermutation in immunoglobulin variable and switch regions. Immunologic Research. 47: 113-22. PMID 20082153 DOI: 10.1007/S12026-009-8142-5 |
0.309 |
|
| 2009 |
Rajagopal D, Maul RW, Ghosh A, Chakraborty T, Khamlichi AA, Sen R, Gearhart PJ. Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation. The Journal of Experimental Medicine. 206: 1237-44. PMID 19433618 DOI: 10.1084/Jem.20082514 |
0.69 |
|
| 2009 |
Saribasak H, Rajagopal D, Maul RW, Gearhart PJ. Hijacked DNA repair proteins and unchained DNA polymerases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 364: 605-11. PMID 19008198 DOI: 10.1098/Rstb.2008.0188 |
0.697 |
|
| 2005 |
Martomo SA, Fu D, Yang WW, Joshi NS, Gearhart PJ. Deoxyuridine is generated preferentially in the nontranscribed strand of DNA from cells expressing activation-induced cytidine deaminase. Journal of Immunology (Baltimore, Md. : 1950). 174: 7787-91. PMID 15944282 |
0.306 |
|
| 2005 |
Martomo SA, Yang WW, Wersto RP, Ohkumo T, Kondo Y, Yokoi M, Masutani C, Hanaoka F, Gearhart PJ. Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. Proceedings of the National Academy of Sciences of the United States of America. 102: 8656-61. PMID 15939880 DOI: 10.1073/pnas.0501852102 |
0.387 |
|
| 2005 |
Wilson TM, Vaisman A, Martomo SA, Sullivan P, Lan L, Hanaoka F, Yasui A, Woodgate R, Gearhart PJ. MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes. The Journal of Experimental Medicine. 201: 637-45. PMID 15710654 DOI: 10.1084/jem.20042066 |
0.354 |
|
| 2004 |
Lumsden JM, McCarty T, Petiniot LK, Shen R, Barlow C, Wynn TA, Morse HC, Gearhart PJ, Wynshaw-Boris A, Max EE, Hodes RJ. Immunoglobulin class switch recombination is impaired in Atm-deficient mice. The Journal of Experimental Medicine. 200: 1111-21. PMID 15504820 DOI: 10.1084/Jem.20041074 |
0.508 |
|
| 2003 |
Gearhart PJ. B cells pay a price. Oncogene. 22: 5379-80. PMID 12934096 DOI: 10.1038/sj.onc.1206874 |
0.317 |
|
| 2003 |
Winter DB, Phung QH, Zeng X, Seeberg E, Barnes DE, Lindahl T, Gearhart PJ. Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase. Journal of Immunology (Baltimore, Md. : 1950). 170: 5558-62. PMID 12759433 |
0.355 |
|
| 2001 |
Winter DB, Gearhart PJ. Altered spectra of hypermutation in DNA repair-deficient mice. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 5-11. PMID 11205330 DOI: 10.1098/rstb.2000.0742 |
0.363 |
|
| 2000 |
Winter DB, Phung QH, Wood RD, Gearhart PJ. Differential expression of DNA polymerase epsilon in resting and activated B lymphocytes is consistent with an in vivo role in replication and not repair. Molecular Immunology. 37: 125-31. PMID 10865111 DOI: 10.1016/S0161-5890(00)00040-7 |
0.381 |
|
| 1998 |
Phung QH, Winter DB, Cranston A, Tarone RE, Bohr VA, Fishel R, Gearhart PJ. Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein Journal of Experimental Medicine. 187: 1745-1750. PMID 9607916 DOI: 10.1084/jem.187.11.1745 |
0.307 |
|
| 1997 |
Winter DB, Sattar N, Mai JJ, Gearhart PJ. Insertion of 2 kb of bacteriophage DNA between an immunoglobulin promoter and leader exon stops somatic hypermutation in a kappa transgene. Molecular Immunology. 34: 359-66. PMID 9293769 DOI: 10.1016/S0161-5890(97)00073-4 |
0.311 |
|
| 1995 |
Umar A, Gearhart PJ. Reciprocal homologous recombination in or near antibody VDJ genes. European Journal of Immunology. 25: 2392-400. PMID 7664801 DOI: 10.1002/eji.1830250840 |
0.316 |
|
| 1987 |
Malipiero UV, Levy NS, Gearhart PJ. Somatic mutation in anti-phosphorylcholine antibodies. Immunological Reviews. 96: 59-74. PMID 3298010 DOI: 10.1111/j.1600-065X.1987.tb00509.x |
0.327 |
|
| 1987 |
Lawler AM, Lin PS, Gearhart PJ. Adult B-cell repertoire is biased toward two heavy-chain variable-region genes that rearrange frequently in fetal pre-B cells Proceedings of the National Academy of Sciences of the United States of America. 84: 2454-2458. PMID 3104915 DOI: 10.1073/pnas.84.8.2454 |
0.391 |
|
| 1984 |
Gearhart PJ. The adaptable somatic repertoire. Annales D'Immunologie. 137-42. PMID 6424549 DOI: 10.1016/S0769-2625(84)80023-9 |
0.354 |
|
| 1981 |
Gearhart PJ, Johnson ND, Douglas R, Hood L. IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts. Nature. 291: 29-34. PMID 7231520 DOI: 10.1038/291029a0 |
0.306 |
|
| 1981 |
Pierce SK, Speck NA, Gleason K, Gearhart PJ, Köhler H. BALB/c T cells have the potential to recognize the TEPC 15 prototype antibody and its somatic variants Journal of Experimental Medicine. 154: 1178-1187. PMID 6974760 DOI: 10.1084/Jem.154.4.1178 |
0.589 |
|
| 1980 |
Gearhart PJ, Hurwitz JL, Cebra JJ. Successive switching of antibody isotypes expressed within the lines of a B-cell clone. Proceedings of the National Academy of Sciences of the United States of America. 77: 5424-8. PMID 6776537 DOI: 10.1073/pnas.77.9.5424 |
0.473 |
|
| 1979 |
Gearhart PJ, Cebra JJ. Differentiated B lymphocytes. Potential to express particular antibody variable and constant regions depends on site of lymphoid tissue and antigen load. The Journal of Experimental Medicine. 149: 216-27. PMID 105075 DOI: 10.1084/Jem.149.1.216 |
0.48 |
|
| 1978 |
Gearhart PJ, Cebra JJ. Idiotype sharing by murine strains differing in immunoglobulin allotype. Nature. 272: 264-5. PMID 415255 DOI: 10.1038/272264A0 |
0.33 |
|
| 1978 |
Cebra JJ, Emmons R, Gearhart PJ, Robertson SM, Tseng J. Cellular parameters of the IgA response. Advances in Experimental Medicine and Biology. 107: 19-28. PMID 311137 DOI: 10.1007/978-1-4684-3369-2_3 |
0.341 |
|
| 1977 |
Cebra JJ, Gearhart PJ, Kamat R, Robertson SM, Tseng J. The secretory immunoglobulin A response in the gut [proceedings]. Biochemical Society Transactions. 5: 1565-9. PMID 923983 DOI: 10.1042/Bst0051565 |
0.373 |
|
| 1977 |
Cebra JJ, Kamat R, Gearhart P, Robertson SM, Tseng J. The secretory IgA system of the gut. Ciba Foundation Symposium. 5-28. PMID 346328 DOI: 10.1002/9780470720288.ch2 |
0.396 |
|
| 1977 |
Accolla RS, Gearhart PJ, Sigal NH, Cancro MP, Klinman NR. Idiotype-specific neonatal suppression of phosphorylcholine-responsive B cells. European Journal of Immunology. 7: 876-81. PMID 75802 DOI: 10.1002/Eji.1830071211 |
0.74 |
|
| 1977 |
Cebra JJ, Gearhart PJ, Kamat R, Robertson SM, Tseng J. Origin and differentiation of lymphocytes involved in the secretory IgA responses. Cold Spring Harbor Symposia On Quantitative Biology. 41: 201-15. PMID 70311 DOI: 10.1101/Sqb.1977.041.01.026 |
0.356 |
|
| 1977 |
Gearhart PJ, Sigal NH, Klinman NR. The monoclonal anti phosphorylcholine antibody response in several murine strains: genetic implications of a diverse repertoire Journal of Experimental Medicine. 145: 876-891. PMID 67172 DOI: 10.1084/Jem.145.4.876 |
0.654 |
|
| 1976 |
Klinman NR, Sigal NH, Metcalf ES, Pierce SK, Gearhart PJ. The interplay of evolution and environment in B cell diversification Origins of Lymphocyte Diversity Cold Spring Harbor Symposia On Quantitative Biology. 41: 165-173. PMID 70310 DOI: 10.1101/Sqb.1977.041.01.022 |
0.738 |
|
| 1975 |
Gearhart PJ, Sigal NH, Klinman NR. Production of antibodies of identical idiotype but diverse immunoglobulin classes by cells derived from a single stimulated B cell Proceedings of the National Academy of Sciences of the United States of America. 72: 1707-1711. PMID 1080568 DOI: 10.1073/Pnas.72.5.1707 |
0.669 |
|
| 1975 |
Gearhart PJ, Sigal NH, Klinman NR. Heterogeneity of the BALB/c antiphosphorylcholine antibody response at the precursor cell level Journal of Experimental Medicine. 141: 56-71. PMID 46913 DOI: 10.1084/Jem.141.1.56 |
0.697 |
|
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