| Year |
Citation |
Score |
| 2024 |
Lee-Ferris RE, Okuda K, Galiger JR, Schworer SA, Rogers TD, Dang H, Gilmore R, Edwards C, Nakano S, Cawley AM, Pickles RJ, Gallant SC, Crisci E, Rivier L, Hagood JS, et al. Prolonged airway explant culture enables study of health, disease, and viral pathogenesis. Biorxiv : the Preprint Server For Biology. PMID 38370820 DOI: 10.1101/2024.02.03.578756 |
0.32 |
|
| 2024 |
McSweeney MD, Alnajjar S, Schaefer AM, Richardson Z, Wolf W, Stewart I, Sriboonyapirat P, McCallen J, Farmer E, Nzati B, Lord S, Farrer B, Moench TR, Kumar PA, Arora H, ... Pickles RJ, et al. Inhaled "Muco-Trapping" Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2306729. PMID 38225749 DOI: 10.1002/advs.202306729 |
0.418 |
|
| 2023 |
De C, Pickles RJ, Yao W, Liao B, Boone AE, Choi M, Battaglia DM, Askin FB, Whitmire JK, Silvestri G, Garcia JV, Wahl A. Human T cells efficiently control RSV infection. Jci Insight. PMID 37159271 DOI: 10.1172/jci.insight.168110 |
0.387 |
|
| 2023 |
Pearson J, Wessler T, Chen A, Boucher RC, Freeman R, Lai SK, Pickles R, Gregory Forest M. Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 hours post infection. Journal of Theoretical Biology. 565: 111470. PMID 36965846 DOI: 10.1016/j.jtbi.2023.111470 |
0.385 |
|
| 2022 |
Chen A, Wessler T, Daftari K, Hinton K, Boucher RC, Pickles R, Freeman R, Lai SK, Forest MG. Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection. Biophysical Journal. PMID 35378080 DOI: 10.1016/j.bpj.2022.04.003 |
0.379 |
|
| 2021 |
Wahl A, Gralinski LE, Johnson CE, Yao W, Kovarova M, Dinnon KH, Liu H, Madden VJ, Krzystek HM, De C, White KK, Gully K, Schäfer A, Zaman T, Leist SR, ... ... Pickles RJ, et al. SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801. Nature. PMID 33561864 DOI: 10.1038/s41586-021-03312-w |
0.487 |
|
| 2020 |
Cruz-Teran C, Tiruthani K, McSweeney M, Ma A, Pickles R, Lai SK. Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy. Advanced Drug Delivery Reviews. PMID 33309815 DOI: 10.1016/j.addr.2020.12.004 |
0.304 |
|
| 2020 |
Wahl A, Gralinski L, Johnson C, Yao W, Kovarova M, Dinnon K, Liu H, Madden V, Krzystek H, De C, White K, Schäfer A, Zaman T, Leist S, Grant P, ... ... Pickles R, et al. Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801. Research Square. PMID 32995766 DOI: 10.21203/rs.3.rs-80404/v1 |
0.485 |
|
| 2019 |
Wahl A, De C, Abad Fernandez M, Lenarcic EM, Xu Y, Cockrell AS, Cleary RA, Johnson CE, Schramm NJ, Rank LM, Newsome IG, Vincent HA, Sanders W, Aguilera-Sandoval CR, Boone A, ... ... Pickles RJ, et al. Precision mouse models with expanded tropism for human pathogens. Nature Biotechnology. PMID 31451733 DOI: 10.1038/S41587-019-0225-9 |
0.487 |
|
| 2016 |
Stobart CC, Rostad CA, Ke Z, Dillard RS, Hampton CM, Strauss JD, Yi H, Hotard AL, Meng J, Pickles RJ, Sakamoto K, Lee S, Currier MG, Moin SM, Graham BS, et al. A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation. Nature Communications. 7: 13916. PMID 28000669 DOI: 10.1038/Ncomms13916 |
0.373 |
|
| 2016 |
Menachery VD, Yount BL, Sims AC, Debbink K, Agnihothram SS, Gralinski LE, Graham RL, Scobey T, Plante JA, Royal SR, Swanstrom J, Sheahan TP, Pickles RJ, Corti D, Randell SH, et al. SARS-like WIV1-CoV poised for human emergence. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976607 DOI: 10.1073/Pnas.1517719113 |
0.478 |
|
| 2015 |
Pickles RJ, DeVincenzo JP. Respiratory syncytial virus (RSV) and its propensity for causing bronchiolitis. The Journal of Pathology. 235: 266-76. PMID 25302625 DOI: 10.1002/Path.4462 |
0.543 |
|
| 2014 |
Liesman RM, Buchholz UJ, Luongo CL, Yang L, Proia AD, DeVincenzo JP, Collins PL, Pickles RJ. RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction. The Journal of Clinical Investigation. 124: 2219-33. PMID 24713657 DOI: 10.1172/Jci72948 |
0.807 |
|
| 2014 |
Brockman-Schneider RA, Pickles RJ, Gern JE. Effects of vitamin D on airway epithelial cell morphology and rhinovirus replication. Plos One. 9: e86755. PMID 24475177 DOI: 10.1371/Journal.Pone.0086755 |
0.33 |
|
| 2013 |
Pickles RJ. Human airway epithelial cell cultures for modeling respiratory syncytial virus infection. Current Topics in Microbiology and Immunology. 372: 371-87. PMID 24362700 DOI: 10.1007/978-3-642-38919-1_19 |
0.589 |
|
| 2013 |
Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR, Burkett SE, Zornetzer G, Tseng CT, ... ... Pickles R, et al. Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. Journal of Virology. 87: 3885-902. PMID 23365422 DOI: 10.1128/Jvi.02520-12 |
0.572 |
|
| 2013 |
Kesimer M, Ehre C, Burns KA, Davis CW, Sheehan JK, Pickles RJ. Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways. Mucosal Immunology. 6: 379-92. PMID 22929560 DOI: 10.1038/Mi.2012.81 |
0.337 |
|
| 2012 |
Ehre C, Worthington EN, Liesman RM, Grubb BR, Barbier D, O'Neal WK, Sallenave JM, Pickles RJ, Boucher RC. Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs Proceedings of the National Academy of Sciences of the United States of America. 109: 16528-16533. PMID 23012413 DOI: 10.1073/Pnas.1206552109 |
0.778 |
|
| 2012 |
Schaap-Nutt A, Liesman R, Bartlett EJ, Scull MA, Collins PL, Pickles RJ, Schmidt AC. Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium. Virology. 433: 320-8. PMID 22959894 DOI: 10.1016/J.Virol.2012.08.027 |
0.793 |
|
| 2011 |
Frieman M, Basu D, Matthews K, Taylor J, Jones G, Pickles R, Baric R, Engel DA. Yeast based small molecule screen for inhibitors of SARS-CoV. Plos One. 6: e28479. PMID 22164298 DOI: 10.1371/Journal.Pone.0028479 |
0.433 |
|
| 2011 |
van Doremalen N, Shelton H, Roberts KL, Jones IM, Pickles RJ, Thompson CI, Barclay WS. A single amino acid in the HA of pH1N1 2009 influenza virus affects cell tropism in human airway epithelium, but not transmission in ferrets. Plos One. 6: e25755. PMID 21998692 DOI: 10.1371/Journal.Pone.0025755 |
0.538 |
|
| 2011 |
Zhang L, Collins PL, Lamb RA, Pickles RJ. Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus. Virology. 421: 67-77. PMID 21986028 DOI: 10.1016/J.Virol.2011.08.020 |
0.603 |
|
| 2011 |
Nguyen Y, Procario MC, Ashley SL, O'Neal WK, Pickles RJ, Weinberg JB. Limited effects of Muc1 deficiency on mouse adenovirus type 1 respiratory infection. Virus Research. 160: 351-9. PMID 21816184 DOI: 10.1016/J.Virusres.2011.07.012 |
0.431 |
|
| 2011 |
Li W, Zhang L, Wu Z, Pickles RJ, Samulski RJ. AAV-6 mediated efficient transduction of mouse lower airways. Virology. 417: 327-33. PMID 21752418 DOI: 10.1016/J.Virol.2011.06.009 |
0.411 |
|
| 2011 |
Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways. Immunity. 34: 854-65. PMID 21703540 DOI: 10.1016/J.Immuni.2011.03.026 |
0.75 |
|
| 2011 |
Johnson JS, Gentzsch M, Zhang L, Ribeiro CM, Kantor B, Kafri T, Pickles RJ, Samulski RJ. AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis. Plos Pathogens. 7: e1002053. PMID 21625534 DOI: 10.1371/Journal.Ppat.1002053 |
0.498 |
|
| 2011 |
Roberts KL, Shelton H, Scull M, Pickles R, Barclay WS. Lack of transmission of a human influenza virus with avian receptor specificity between ferrets is not due to decreased virus shedding but rather a lower infectivity in vivo. The Journal of General Virology. 92: 1822-31. PMID 21508186 DOI: 10.1099/Vir.0.031203-0 |
0.779 |
|
| 2011 |
Shelton H, Ayora-Talavera G, Ren J, Loureiro S, Pickles RJ, Barclay WS, Jones IM. Receptor binding profiles of avian influenza virus hemagglutinin subtypes on human cells as a predictor of pandemic potential. Journal of Virology. 85: 1875-80. PMID 21106732 DOI: 10.1128/Jvi.01822-10 |
0.546 |
|
| 2011 |
Okada SF, Zhang L, Kreda SM, Abdullah LH, Davis CW, Pickles RJ, Lazarowski ER, Boucher RC. Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epithelium. American Journal of Respiratory Cell and Molecular Biology. 45: 253-60. PMID 20935191 DOI: 10.1165/Rcmb.2010-0253Oc |
0.391 |
|
| 2010 |
Zhang L, Limberis MP, Thompson C, Antunes MB, Luongo C, Wilson JM, Collins PL, Pickles RJ. α-Fetoprotein gene delivery to the nasal epithelium of nonhuman primates by human parainfluenza viral vectors. Human Gene Therapy. 21: 1657-64. PMID 20735256 DOI: 10.1089/Hum.2010.065 |
0.499 |
|
| 2010 |
Pyrc K, Sims AC, Dijkman R, Jebbink M, Long C, Deming D, Donaldson E, Vabret A, Baric R, van der Hoek L, Pickles R. Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures. Journal of Virology. 84: 11255-63. PMID 20719951 DOI: 10.1128/Jvi.00947-10 |
0.53 |
|
| 2010 |
Kwilas AR, Yednak MA, Zhang L, Liesman R, Collins PL, Pickles RJ, Peeples ME. Respiratory syncytial virus engineered to express the cystic fibrosis transmembrane conductance regulator corrects the bioelectric phenotype of human cystic fibrosis airway epithelium in vitro. Journal of Virology. 84: 7770-81. PMID 20504917 DOI: 10.1128/Jvi.00346-10 |
0.786 |
|
| 2010 |
Heiniger RW, Winther-Larsen HC, Pickles RJ, Koomey M, Wolfgang MC. Infection of human mucosal tissue by Pseudomonas aeruginosa requires sequential and mutually dependent virulence factors and a novel pilus-associated adhesin. Cellular Microbiology. 12: 1158-73. PMID 20331639 DOI: 10.1111/J.1462-5822.2010.01461.X |
0.411 |
|
| 2010 |
Eby JC, Ciesla WP, Hamman W, Donato GM, Pickles RJ, Hewlett EL, Lencer WI. Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cells. The Journal of Biological Chemistry. 285: 10662-70. PMID 20139088 DOI: 10.1074/Jbc.M109.089219 |
0.326 |
|
| 2010 |
Schaap-Nutt A, Scull MA, Schmidt AC, Murphy BR, Pickles RJ. Growth restriction of an experimental live attenuated human parainfluenza virus type 2 vaccine in human ciliated airway epithelium in vitro parallels attenuation in African green monkeys. Vaccine. 28: 2788-98. PMID 20139039 DOI: 10.1016/J.Vaccine.2010.01.050 |
0.769 |
|
| 2010 |
Schaap-Nutt A, D'Angelo C, Scull MA, Amaro-Carambot E, Nishio M, Pickles RJ, Collins PL, Murphy BR, Schmidt AC. Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates. Virology. 397: 285-98. PMID 19969320 DOI: 10.1016/J.Virol.2009.11.018 |
0.753 |
|
| 2009 |
Ayora-Talavera G, Shelton H, Scull MA, Ren J, Jones IM, Pickles RJ, Barclay WS. Mutations in H5N1 influenza virus hemagglutinin that confer binding to human tracheal airway epithelium. Plos One. 4: e7836. PMID 19924306 DOI: 10.1371/Journal.Pone.0007836 |
0.76 |
|
| 2009 |
Kwilas S, Liesman RM, Zhang L, Walsh E, Pickles RJ, Peeples ME. Respiratory syncytial virus grown in Vero cells contains a truncated attachment protein that alters its infectivity and dependence on glycosaminoglycans. Journal of Virology. 83: 10710-8. PMID 19656891 DOI: 10.1128/Jvi.00986-09 |
0.795 |
|
| 2009 |
Zhang L, Button B, Gabriel SE, Burkett S, Yan Y, Skiadopoulos MH, Dang YL, Vogel LN, McKay T, Mengos A, Boucher RC, Collins PL, Pickles RJ. CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium. Plos Biology. 7: e1000155. PMID 19621064 DOI: 10.1371/Journal.Pbio.1000155 |
0.373 |
|
| 2009 |
Li W, Zhang L, Johnson JS, Zhijian W, Grieger JC, Ping-Jie X, Drouin LM, Agbandje-McKenna M, Pickles RJ, Samulski RJ. Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2067-77. PMID 19603002 DOI: 10.1038/Mt.2009.155 |
0.436 |
|
| 2009 |
Scull MA, Gillim-Ross L, Santos C, Roberts KL, Bordonali E, Subbarao K, Barclay WS, Pickles RJ. Avian Influenza virus glycoproteins restrict virus replication and spread through human airway epithelium at temperatures of the proximal airways. Plos Pathogens. 5: e1000424. PMID 19436701 DOI: 10.1371/Journal.Ppat.1000424 |
0.774 |
|
| 2009 |
Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. MAVS-mediated apoptosis and its inhibition by viral proteins. Plos One. 4: e5466. PMID 19404494 DOI: 10.1371/Journal.Pone.0005466 |
0.767 |
|
| 2009 |
Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 30: 556-65. PMID 19362020 DOI: 10.1016/J.Immuni.2009.02.005 |
0.765 |
|
| 2009 |
Kesimer M, Scull M, Brighton B, DeMaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK. Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1858-68. PMID 19190083 DOI: 10.1096/Fj.08-119131 |
0.725 |
|
| 2009 |
Limberis MP, Vandenberghe LH, Zhang L, Pickles RJ, Wilson JM. Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 294-301. PMID 19066597 DOI: 10.1038/Mt.2008.261 |
0.448 |
|
| 2009 |
Bukreyev A, Marzi A, Feldmann F, Zhang L, Yang L, Ward JM, Dorward DW, Pickles RJ, Murphy BR, Feldmann H, Collins PL. Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge. Virology. 383: 348-61. PMID 19010509 DOI: 10.1016/J.Virol.2008.09.030 |
0.571 |
|
| 2009 |
Kesimer M, Kirkham S, Pickles RJ, Henderson AG, Alexis NE, Demaria G, Knight D, Thornton DJ, Sheehan JK. Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L92-L100. PMID 18931053 DOI: 10.1152/Ajplung.90388.2008 |
0.348 |
|
| 2008 |
Becker MM, Graham RL, Donaldson EF, Rockx B, Sims AC, Sheahan T, Pickles RJ, Corti D, Johnston RE, Baric RS, Denison MR. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 19944-9. PMID 19036930 DOI: 10.1073/Pnas.0808116105 |
0.444 |
|
| 2008 |
Donaldson EF, Yount B, Sims AC, Burkett S, Pickles RJ, Baric RS. Systematic assembly of a full-length infectious clone of human coronavirus NL63. Journal of Virology. 82: 11948-57. PMID 18818320 DOI: 10.1128/Jvi.01804-08 |
0.514 |
|
| 2008 |
Bartlett EJ, Cruz AM, Esker J, Castaño A, Schomacker H, Surman SR, Hennessey M, Boonyaratanakornkit J, Pickles RJ, Collins PL, Murphy BR, Schmidt AC. Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primates. Journal of Virology. 82: 8965-77. PMID 18614629 DOI: 10.1128/Jvi.00853-08 |
0.404 |
|
| 2008 |
Bartlett EJ, Hennessey M, Skiadopoulos MH, Schmidt AC, Collins PL, Murphy BR, Pickles RJ. Role of interferon in the replication of human parainfluenza virus type 1 wild type and mutant viruses in human ciliated airway epithelium. Journal of Virology. 82: 8059-70. PMID 18524813 DOI: 10.1128/Jvi.02263-07 |
0.529 |
|
| 2008 |
Sims AC, Burkett SE, Yount B, Pickles RJ. SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium. Virus Research. 133: 33-44. PMID 17451829 DOI: 10.1016/J.Virusres.2007.03.013 |
0.591 |
|
| 2008 |
Sheehan JK, Kesimer M, Pickles R. Innate Immunity and Mucus Structure and Function Novartis Foundation Symposium. 279: 155-169. DOI: 10.1002/9780470035399.Ch13 |
0.379 |
|
| 2007 |
Sheahan T, Rockx B, Donaldson E, Sims A, Pickles R, Corti D, Baric R. Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. Journal of Virology. 82: 2274-85. PMID 18094188 DOI: 10.1128/Jvi.02041-07 |
0.504 |
|
| 2007 |
Chapman J, Abbott E, Alber DG, Baxter RC, Bithell SK, Henderson EA, Carter MC, Chambers P, Chubb A, Cockerill GS, Collins PL, Dowdell VC, Keegan SJ, Kelsey RD, Lockyer MJ, ... ... Pickles RJ, et al. RSV604, a novel inhibitor of respiratory syncytial virus replication. Antimicrobial Agents and Chemotherapy. 51: 3346-53. PMID 17576833 DOI: 10.1128/Aac.00211-07 |
0.541 |
|
| 2007 |
Rockx B, Sheahan T, Donaldson E, Harkema J, Sims A, Heise M, Pickles R, Cameron M, Kelvin D, Baric R. Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice. Journal of Virology. 81: 7410-23. PMID 17507479 DOI: 10.1128/Jvi.00505-07 |
0.468 |
|
| 2007 |
Hall JD, Craven RR, Fuller JR, Pickles RJ, Kawula TH. Francisella tularensis replicates within alveolar type II epithelial cells in vitro and in vivo following inhalation. Infection and Immunity. 75: 1034-9. PMID 17088343 DOI: 10.1128/Iai.01254-06 |
0.393 |
|
| 2007 |
Kesimer M, Matthews G, DeMaria G, Henderson AG, Pickles RJ, Sheehan JK. Proteomic and biochemical analysis of exosomes isolated from human tracheobronchial epithelial cell culture secretions The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A268-A |
0.364 |
|
| 2006 |
Deming D, Sheahan T, Heise M, Yount B, Davis N, Sims A, Suthar M, Harkema J, Whitmore A, Pickles R, West A, Donaldson E, Curtis K, Johnston R, Baric R. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. Plos Medicine. 3: e525. PMID 17194199 DOI: 10.1371/Journal.Pmed.0030525 |
0.388 |
|
| 2006 |
Sheahan T, Deming D, Donaldson E, Pickles R, Baric R. Resurrection of an "extinct" SARS-CoV isolate GD03 from late 2003. Advances in Experimental Medicine and Biology. 581: 547-50. PMID 17037596 DOI: 10.1007/978-0-387-33012-9_100 |
0.463 |
|
| 2006 |
Sims AC, Yount B, Burkett SE, Baric RS, Pickles RJ. SARS CoV replication and pathogenesis in human airway epithelial cultures. Advances in Experimental Medicine and Biology. 581: 535-8. PMID 17037593 DOI: 10.1007/978-0-387-33012-9_97 |
0.446 |
|
| 2006 |
Thompson CI, Barclay WS, Zambon MC, Pickles RJ. Infection of human airway epithelium by human and avian strains of influenza a virus. Journal of Virology. 80: 8060-8. PMID 16873262 DOI: 10.1128/Jvi.00384-06 |
0.601 |
|
| 2006 |
McKay T, Patel M, Pickles RJ, Johnson LG, Olsen JC. Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors. Gene Therapy. 13: 715-24. PMID 16397505 DOI: 10.1038/Sj.Gt.3302715 |
0.509 |
|
| 2006 |
Surowitz JB, Patel K, Leight D, Zhang L, Pickles R, Randell S, Buchman CA. R058: Differential Cytokine Induction by PIV and RSV Infection Otolaryngology–Head and Neck Surgery. 135: P124-P124. DOI: 10.1016/J.Otohns.2006.06.811 |
0.337 |
|
| 2005 |
Sims AC, Baric RS, Yount B, Burkett SE, Collins PL, Pickles RJ. Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs. Journal of Virology. 79: 15511-24. PMID 16306622 DOI: 10.1128/Jvi.79.24.15511-15524.2005 |
0.583 |
|
| 2005 |
Tarran R, Button B, Picher M, Paradiso AM, Ribeiro CM, Lazarowski ER, Zhang L, Collins PL, Pickles RJ, Fredberg JJ, Boucher RC. Normal and cystic fibrosis airway surface liquid homeostasis. The effects of phasic shear stress and viral infections. The Journal of Biological Chemistry. 280: 35751-9. PMID 16087672 DOI: 10.1074/Jbc.M505832200 |
0.41 |
|
| 2005 |
Pickles RJ. Towards a gene therapy for cystic fibrosis lung disease. Expert Opinion On Investigational Drugs. 6: 1459-63. PMID 15989512 DOI: 10.1517/13543784.6.10.1459 |
0.366 |
|
| 2005 |
Das S, Palmer OP, Leight WD, Surowitz JB, Pickles RJ, Randell SH, Buchman CA. Cytokine amplification by respiratory syncytial virus infection in human nasal epithelial cells. The Laryngoscope. 115: 764-8. PMID 15867636 DOI: 10.1097/01.Mlg.0000159527.76949.93 |
0.496 |
|
| 2005 |
Zhang L, Bukreyev A, Thompson CI, Watson B, Peeples ME, Collins PL, Pickles RJ. Infection of ciliated cells by human parainfluenza virus type 3 in an in vitro model of human airway epithelium. Journal of Virology. 79: 1113-24. PMID 15613339 DOI: 10.1128/Jvi.79.2.1113-1124.2005 |
0.582 |
|
| 2005 |
PATEL K, POSTON A, DIXON J, ZHANG L, PICKLES R, RANDELL S, BUCHMAN C. Cytokine Induction by Parainfluenza Virus and Streptococcus Pneumoniae in Human Airway Epithelial Cells Otolaryngology - Head and Neck Surgery. 133: P159-P159. DOI: 10.1016/J.Otohns.2005.05.358 |
0.601 |
|
| 2005 |
KOLLN K, ANTONIOU R, SENIOR B, ZHANG L, PICKLES R, RANDELL S, BUCHMAN C. Respiratory Syncytial Virus Infection in Well-Differentiated Sinus Epithelial Cells Otolaryngology - Head and Neck Surgery. 133: P103-P103. DOI: 10.1016/J.Otohns.2005.05.219 |
0.562 |
|
| 2004 |
Stonebraker JR, Wagner D, Lefensty RW, Burns K, Gendler SJ, Bergelson JM, Boucher RC, O'Neal WK, Pickles RJ. Glycocalyx restricts adenoviral vector access to apical receptors expressed on respiratory epithelium in vitro and in vivo: role for tethered mucins as barriers to lumenal infection. Journal of Virology. 78: 13755-68. PMID 15564484 DOI: 10.1128/Jvi.78.24.13755-13768.2004 |
0.387 |
|
| 2004 |
Mellow TE, Murphy PC, Carson JL, Noah TL, Zhang L, Pickles RJ. The effect of respiratory synctial virus on chemokine release by differentiated airway epithelium. Experimental Lung Research. 30: 43-57. PMID 14967603 DOI: 10.1080/01902140490252812 |
0.527 |
|
| 2004 |
Zhang L, Button B, Skiadopoulos MH, Dang Y, Bukreyev A, Gabriel SE, Collins PL, Pickles RJ. 687. Parainfluenza virus-mediated delivery of CFTR to ciliated cells corrects the CF bioelectrical chloride secretory defect and restores the regulation of airway surface liquid depth and mucus transport to cystic fibrosis airway epithelium Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.584 |
0.383 |
|
| 2004 |
McKay TR, Patel M, Giddings AM, Pickles RJ, Olsen JC. 492. Characterization of the Apical Transduction of Well-Differentiated Mouse Tracheal Cultures by an Equine Lentivirus Pseudotyped with Avian Influenza Coat Proteins Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.408 |
0.521 |
|
| 2003 |
Hutchin ME, Pickles RJ, Yarbrough WG. Efficiency of adenovirus-mediated gene transfer to oropharyngeal epithelial cells correlates with cellular differentiation and human coxsackie and adenovirus receptor expression. Human Gene Therapy. 11: 2365-75. PMID 11096441 DOI: 10.1089/104303400750038471 |
0.42 |
|
| 2002 |
Zhang L, Peeples ME, Boucher RC, Collins PL, Pickles RJ. Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology. Journal of Virology. 76: 5654-66. PMID 11991994 DOI: 10.1128/Jvi.76.11.5654-5666.2002 |
0.579 |
|
| 2001 |
Cohen CJ, Shieh JT, Pickles RJ, Okegawa T, Hsieh JT, Bergelson JM. The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction. Proceedings of the National Academy of Sciences of the United States of America. 98: 15191-6. PMID 11734628 DOI: 10.1073/Pnas.261452898 |
0.465 |
|
| 2000 |
Pickles RJ, Fahrner JA, Petrella JM, Boucher RC, Bergelson JM. Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer Journal of Virology. 74: 6050-6057. PMID 10846088 DOI: 10.1128/Jvi.74.13.6050-6057.2000 |
0.408 |
|
| 2000 |
Kreda SM, Pickles RJ, Lazarowski ER, Boucher RC. G-protein-coupled receptors as targets for gene transfer vectors using natural small-molecule ligands. Nature Biotechnology. 18: 635-40. PMID 10835601 DOI: 10.1038/76479 |
0.326 |
|
| 2000 |
Pickles R. Novel vector improves efficiency of gene transfer to the airway epithelium Respiratory Research. 2. DOI: 10.1186/Rr-2001-68535 |
0.313 |
|
| 1998 |
Pickles RJ, McCarty D, Matsui H, Hart PJ, Randell SH, Boucher RC. Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer Journal of Virology. 72: 6014-6023. PMID 9621064 DOI: 10.1128/Jvi.72.7.6014-6023.1998 |
0.438 |
|
| 1998 |
Batra RK, Olsen JC, Pickles RJ, Hoganson DK, Boucher RC. Transduction of non-small cell lung cancer cells by adenoviral and retroviral vectors. American Journal of Respiratory Cell and Molecular Biology. 18: 402-10. PMID 9490658 DOI: 10.1165/Ajrcmb.18.3.2784 |
0.36 |
|
| 1997 |
Piedimonte G, Pickles RJ, Lehmann JR, McCarty D, Costa DL, Boucher RC. Replication-deficient adenoviral vector for gene transfer potentiates airway neurogenic inflammation. American Journal of Respiratory Cell and Molecular Biology. 16: 250-8. PMID 9070609 DOI: 10.1165/Ajrcmb.16.3.9070609 |
0.415 |
|
| 1996 |
Johnson LG, Pickles RJ, Boyles SE, Morris JC, Ye H, Zhou Z, Olsen JC, Boucher RC. In vitro assessment of variables affecting the efficiency and efficacy of adenovirus-mediated gene transfer to cystic fibrosis airway epithelia. Human Gene Therapy. 7: 51-9. PMID 8825868 DOI: 10.1089/Hum.1996.7.1-51 |
0.373 |
|
| 1996 |
Pickles RJ, Barker PM, Ye H, Boucher RC. Efficient adenovirus-mediated gene transfer to basal but not columnar cells of cartilaginous airway epithelia. Human Gene Therapy. 7: 921-31. PMID 8727506 DOI: 10.1089/Hum.1996.7.8-921 |
0.444 |
|
| 1994 |
Grubb BR, Pickles RJ, Ye H, Yankaskas JR, Vick RN, Engelhardt JF, Wilson JM, Johnson LG, Boucher RC. Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans. Nature. 371: 802-6. PMID 7523956 DOI: 10.1038/371802A0 |
0.393 |
|
| 1994 |
Boucher RC, Knowles MR, Johnson LG, Olsen JC, Pickles R, Wilson JM, Engelhardt J, Yang Y, Grossman M. Gene therapy for cystic fibrosis using E1-deleted adenovirus: a phase I trial in the nasal cavity. The University of North Carolina at Chapel Hill. Human Gene Therapy. 5: 615-39. PMID 7519885 DOI: 10.1089/Hum.1994.5.5-615 |
0.407 |
|
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