Alexander Khoruts - Publications

Affiliations: 
Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology, Microbiology Biology, Cell Biology

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pape KA, Dileepan T, Matchett WE, Ellwood C, Stresemann S, Kabage AJ, Kozysa D, Evert C, Matson M, Lopez S, Krueger PD, Graiziger CT, Vaughn BP, Shmidt E, Rhein J, ... ... Khoruts A, et al. Boosting corrects a memory B cell defect in SARS-CoV-2 mRNA-vaccinated patients with inflammatory bowel disease. Jci Insight. 7. PMID 35730567 DOI: 10.1172/jci.insight.159618  0.472
2021 Pape KA, Dileepan T, Kabage AJ, Kozysa D, Batres R, Evert C, Matson M, Lopez S, Krueger PD, Graiziger C, Vaughn BP, Shmidt E, Rhein J, Schacker TW, Khoruts A, et al. High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines. Cell Reports. 37: 109823. PMID 34610291 DOI: 10.1016/j.celrep.2021.109823  0.484
2020 Khoruts A, Staley C, Sadowsky MJ. Faecal microbiota transplantation for Clostridioides difficile: mechanisms and pharmacology. Nature Reviews. Gastroenterology & Hepatology. PMID 32843743 DOI: 10.1038/S41575-020-0350-4  0.381
2020 Matchett WE, Anguiano-Zarate S, Malewana GBR, Mudrick H, Weldy M, Evert C, Khoruts A, Sadowsky M, Barry MA. A Replicating Single-Cycle Adenovirus Vaccine Effective against . Vaccines. 8. PMID 32842679 DOI: 10.3390/Vaccines8030470  0.309
2020 Cheng YW, Alhaffar D, Saha S, Khanna S, Bohm M, Phelps E, Ghabril M, Orman E, Sashidhar S, Rogers N, Xu H, Khoruts A, Vaughn B, Kao D, Wong K, et al. Fecal Microbiota Transplantation is Safe and Effective in Patients with Clostridioides difficile Infection and Cirrhosis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 32645451 DOI: 10.1016/J.Cgh.2020.06.051  0.375
2020 Borges da Silva H, Peng C, Wang H, Wanhainen KM, Ma C, Lopez S, Khoruts A, Zhang N, Jameson SC. Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8 Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β. Immunity. PMID 32640257 DOI: 10.1016/J.Immuni.2020.06.010  0.355
2020 Khoruts A, Bajaj JS. Intestinal microbiota transplantation: Naming a new paradigm. Journal of Hepatology. PMID 32197802 DOI: 10.1016/J.Jhep.2020.02.014  0.355
2020 Bajaj JS, Khoruts A. Microbiota changes and Intestinal Microbiota Transplantation in Liver Diseases and Cirrhosis. Journal of Hepatology. PMID 32004593 DOI: 10.1016/J.Jhep.2020.01.017  0.385
2019 Khoruts A, Hoffmann DE, Palumbo FB. The Impact of Regulatory Policies on the Future of Fecal Microbiota Transplantation. The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics. 47: 482-504. PMID 31957587 DOI: 10.1177/1073110519897726  0.306
2019 Rashidi A, Kaiser T, Graiziger C, Holtan SG, Rehman TU, Weisdorf DJ, Dunny GM, Khoruts A, Staley C. Gut dysbiosis during antileukemia chemotherapy versus allogeneic hematopoietic cell transplantation. Cancer. PMID 31873965 DOI: 10.1002/Cncr.32641  0.374
2019 Rashidi A, Kaiser T, Holtan SG, Rehman TU, Weisdorf DJ, Khoruts A, Staley C. Levaquin gets a pass. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 31870930 DOI: 10.1016/J.Bbmt.2019.12.722  0.361
2019 Holtan S, DeFor TE, Rashidi A, Khoruts A, Staley C, Turcotte LM, Jacobson PA, Weisdorf DJ, MacMillan ML. Pre-Transplant Serum Claudin-3 Predicts Intestinal Graft-Versus-Host Disease and Non-Relapse Mortality Risk after Allogeneic Hematopoietic Cell Transplantation. Blood. 134: 39. PMID 31724001 DOI: 10.1182/Blood-2019-129236  0.352
2019 Adams JB, Borody TJ, Kang DW, Khoruts A, Krajmalnik-Brown R, Sadowsky MJ. Microbiota transplant therapy and autism: lessons for the clinic. Expert Review of Gastroenterology & Hepatology. PMID 31665947 DOI: 10.1080/17474124.2019.1687293  0.317
2019 Rashidi A, Zhu Z, Kaiser T, Manias DA, Holtan SG, Rehman TU, Weisdorf DJ, Khoruts A, Dunny GM, Staley C. Vancomycin-resistance gene cluster, vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy. Plos One. 14: e0223890. PMID 31600332 DOI: 10.1371/Journal.Pone.0223890  0.337
2019 Rashidi A, Kaiser T, Graiziger C, Holtan SG, Rehman TU, Weisdorf DJ, Khoruts A, Staley C. Specific gut microbiota changes heralding bloodstream infection and neutropenic fever during intensive chemotherapy. Leukemia. PMID 31439944 DOI: 10.1038/S41375-019-0547-0  0.338
2019 Huggins MA, Sjaastad FV, Pierson M, Kucaba TA, Swanson W, Staley C, Weingarden AR, Jensen IJ, Danahy DB, Badovinac VP, Jameson SC, Vezys V, Masopust D, Khoruts A, Griffith TS, et al. Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization. Cell Reports. 28: 1729-1743.e5. PMID 31412243 DOI: 10.1016/J.Celrep.2019.07.028  0.722
2019 Holtan SG, Shabaneh A, Betts BC, Rashidi A, MacMillan ML, Ustun C, Amin K, Vaughn BP, Howard J, Khoruts A, Arora M, DeFor TE, Johnson D, Blazar BR, Weisdorf DJ, et al. Stress responses, M2 macrophages, and a distinct microbial signature in fatal intestinal acute graft-versus-host disease. Jci Insight. 5. PMID 31393854 DOI: 10.1172/Jci.Insight.129762  0.354
2019 Staley C, Kaiser T, Vaughn BP, Graiziger C, Hamilton MJ, Kabage AJ, Khoruts A, Sadowsky MJ. Durable Long-Term Bacterial Engraftment following Encapsulated Fecal Microbiota Transplantation To Treat Clostridium difficile Infection. Mbio. 10. PMID 31337728 DOI: 10.1128/Mbio.01586-19  0.419
2019 Khoruts A, Brandt LJ. Fecal Microbiota Transplant: A Rose by Any Other Name. The American Journal of Gastroenterology. PMID 31205129 DOI: 10.14309/Ajg.0000000000000286  0.348
2019 Jahansouz C, Staley C, Kizy S, Xu H, Hertzel AV, Coryell J, Singroy S, Hamilton M, DuRand M, Bernlohr DA, Sadowsky MJ, Khoruts A, Ikramuddin S. Antibiotic-induced Disruption of Intestinal Microbiota Contributes to Failure of Vertical Sleeve Gastrectomy. Annals of Surgery. 269: 1092-1100. PMID 31082907 DOI: 10.1097/Sla.0000000000002729  0.305
2019 Dostal Webster A, Staley C, Hamilton MJ, Huang M, Fryxell K, Erickson R, Kabage AJ, Sadowsky MJ, Khoruts A. Influence of short-term changes in dietary sulfur on the relative abundances of intestinal sulfate-reducing bacteria. Gut Microbes. 1-11. PMID 30810441 DOI: 10.1080/19490976.2018.1559682  0.306
2019 Vaughn BP, Kaiser T, Staley C, Hamilton MJ, Reich J, Graiziger C, Singroy S, Kabage AJ, Sadowsky MJ, Khoruts A. A pilot study of fecal bile acid and microbiota profiles in inflammatory bowel disease and primary sclerosing cholangitis. Clinical and Experimental Gastroenterology. 12: 9-19. PMID 30666146 DOI: 10.2147/Ceg.S186097  0.341
2019 Cheng Y, Alhaffar D, Saha S, Khanna S, Bohm M, Phelps E, Ghabril MS, Orman E, Sagi S, Xu H, Khoruts A, Vaughn BP, Kao DH, Wong K, Cammarota G, et al. Mo1954 – Fecal Microbiota Transplantation is Safe and Effective for the Treatment of Clostridium Difficile Infection in Patients with Liver Cirrhosis Gastroenterology. 156: S-898-S-899. DOI: 10.1016/S0016-5085(19)39217-0  0.365
2019 Holtan SG, Shabaneh A, Rashidi A, Betts BC, MacMillan ML, Ustun C, Amin K, Vaughn B, Howard J, Khoruts A, Knights D, Arora M, Defor TE, Johnson D, Panoskaltsis-Mortari A, et al. RNA Sequencing of Intestinal Biopsies Expands the T Cell-Centric Paradigm of Steroid-Refractory Acute Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 25. DOI: 10.1016/J.Bbmt.2018.12.673  0.396
2019 Rashidi A, Kaiser T, Shields-Cutler R, Graiziger C, Ur Rehman T, Holtan SG, Weisdorf DJ, Knights D, Khoruts A, Staley C. Gut Dysbiosis Increases Gut Barrier Damage during Anti-Leukemia Chemotherapy: Implications for Acute Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 25: S142-S143. DOI: 10.1016/J.Bbmt.2018.12.433  0.338
2019 Rashidi A, Kaiser T, Shields-Cutler R, Graiziger C, Rehman TU, Holtan SG, Weisdorf DJ, Knights D, Khoruts A, Staley C. Outpatient-to-Inpatient Transition Causes Marked Dysbiosis in Allogeneic Hematopoietic Cell Transplantation Recipients Biology of Blood and Marrow Transplantation. 25: S47. DOI: 10.1016/J.Bbmt.2018.12.124  0.347
2018 Rashidi A, Kaiser T, Holtan SG, Weisdorf DJ, Khoruts A, Staley C. Pre-transplant recovery of microbiome diversity without recovery of the original microbiome. Bone Marrow Transplantation. PMID 30498199 DOI: 10.1038/S41409-018-0414-Z  0.323
2018 Rashidi A, Shanley R, Holtan SG, MacMillan ML, Blazar BR, Khoruts A, Weisdorf DJ. Pretransplant Serum Citrulline Predicts Acute Graft-versus-Host Disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 24: 2190-2196. PMID 30454871 DOI: 10.1016/J.Bbmt.2018.06.036  0.347
2018 Amin K, Yaqoob U, Schultz B, Vaughn BP, Khoruts A, Howard JR, DeFor TE, Forster C, Meyer C, Gandhi I, Weisdorf DJ, Rashidi A, MacMillan ML, Blazar BR, Panoskaltsis-Mortari A, et al. Amphiregulin in intestinal acute graft-versus-host disease: a possible diagnostic and prognostic aid. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 30425334 DOI: 10.1038/S41379-018-0170-Z  0.318
2018 Khoruts A. Targeting the microbiome: from probiotics to fecal microbiota transplantation. Genome Medicine. 10: 80. PMID 30376869 DOI: 10.1186/S13073-018-0592-8  0.353
2018 Staley C, Kaiser T, Vaughn BP, Graiziger CT, Hamilton MJ, Rehman TU, Song K, Khoruts A, Sadowsky MJ. Predicting recurrence of Clostridium difficile infection following encapsulated fecal microbiota transplantation. Microbiome. 6: 166. PMID 30227892 DOI: 10.1186/S40168-018-0549-6  0.402
2018 Vaughn BP, Rank KM, Khoruts A. Fecal Microbiota Transplantation: Current Status in Treatment of GI and Liver Disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 30055267 DOI: 10.1016/J.Cgh.2018.07.026  0.401
2018 Khoruts A. Is fecal microbiota transplantation a temporary patch for treatment of Clostridium difficile infection or a new frontier of therapeutics? Expert Review of Gastroenterology & Hepatology. 1-4. PMID 29667436 DOI: 10.1080/17474124.2018.1465818  0.384
2018 Smillie CS, Sauk J, Gevers D, Friedman J, Sung J, Youngster I, Hohmann EL, Staley C, Khoruts A, Sadowsky MJ, Allegretti JR, Smith MB, Xavier RJ, Alm EJ. Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation. Cell Host & Microbe. 23: 229-240.e5. PMID 29447696 DOI: 10.1016/J.Chom.2018.01.003  0.366
2018 Atkins SLP, DeFor TE, MacMillan ML, Turcotte L, Rashidi A, Weisdorf DJ, Khoruts A, Holtan SG. Elevated AREG/EGF Ratio Prior to Transplantation Is Associated with Pre-Transplant Clostridium Difficile Infection, Unresolved Tissue Damage, and Poorer Overall Survival Blood. 132: 3353-3353. DOI: 10.1182/Blood-2018-99-115686  0.348
2018 Amin K, Usman Y, Schultz B, Vaughn B, Howard J, Khoruts A, Defor TE, Forster C, Rashidi A, Weisdorf DJ, MacMillan ML, Blazar BR, Mortari A, Holtan SG. Low Amphiregulin Expression in Intestinal Biopsies of Patients with Acute Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 24: S188. DOI: 10.1016/J.Bbmt.2017.12.142  0.31
2017 Staley C, Khoruts A, Sadowsky MJ. Contemporary Applications of Fecal Microbiota Transplantation to Treat Intestinal Diseases in Humans. Archives of Medical Research. PMID 29183720 DOI: 10.1016/J.Arcmed.2017.11.006  0.415
2017 Staley C, Kaiser T, Beura LK, Hamilton MJ, Weingarden AR, Bobr A, Kang J, Masopust D, Sadowsky MJ, Khoruts A. Stable engraftment of human microbiota into mice with a single oral gavage following antibiotic conditioning. Microbiome. 5: 87. PMID 28760163 DOI: 10.1186/S40168-017-0306-2  0.738
2017 Khanna S, Vazquez-Baeza Y, González A, Weiss S, Schmidt B, Muñiz-Pedrogo DA, Rainey JF, Kammer P, Nelson H, Sadowsky M, Khoruts A, Farrugia SL, Knight R, Pardi DS, Kashyap PC. Changes in microbial ecology after fecal microbiota transplantation for recurrent C. difficile infection affected by underlying inflammatory bowel disease. Microbiome. 5: 55. PMID 28506317 DOI: 10.1186/S40168-017-0269-3  0.399
2017 Stoltz KL, Erickson R, Staley C, Weingarden AR, Romens E, Steer CJ, Khoruts A, Sadowsky MJ, Dosa PI. Synthesis and Biological Evaluation of Bile Acid Analogues Inhibitory to Clostridium difficile Spore Germination. Journal of Medicinal Chemistry. PMID 28402634 DOI: 10.1021/Acs.Jmedchem.7B00295  0.739
2017 Khoruts A. Fecal Microbiota Transplantation - Early Steps on a Long Journey Ahead. Gut Microbes. 0. PMID 28394706 DOI: 10.1080/19490976.2017.1316447  0.339
2017 Staley C, Vaughn BP, Graiziger CT, Singroy S, Hamilton MJ, Yao D, Chen C, Khoruts A, Sadowsky MJ. Community dynamics drive punctuated engraftment of the fecal microbiome following transplantation using freeze-dried, encapsulated fecal microbiota. Gut Microbes. 1-13. PMID 28282270 DOI: 10.1080/19490976.2017.1299310  0.379
2017 Rashidi A, Khoruts A, Weisdorf DJ. Infection Followed by Gvhd: the Pathogenic Role of Antibiotics. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 28257799 DOI: 10.1016/J.Bbmt.2017.02.016  0.34
2017 Staley C, Hamilton MJ, Vaughn BP, Graiziger CT, Newman KM, Kabage AJ, Sadowsky MJ, Khoruts A. Successful Resolution of Recurrent Clostridium difficile Infection using Freeze-Dried, Encapsulated Fecal Microbiota; Pragmatic Cohort Study. The American Journal of Gastroenterology. PMID 28195180 DOI: 10.1038/Ajg.2017.6  0.406
2017 Newman KM, Rank KM, Vaughn BP, Khoruts A. Treatment of recurrent Clostridium difficile infection using fecal microbiota transplantation in patients with inflammatory bowel disease. Gut Microbes. 0. PMID 28102756 DOI: 10.1016/S0016-5085(17)31409-9  0.388
2017 Sadowsky MJ, Staley C, Heiner C, Hall R, Kelly CR, Brandt L, Khoruts A. Analysis of Gut Microbiota - an ever changing landscape. Gut Microbes. 0. PMID 28051919 DOI: 10.1080/19490976.2016.1277313  0.306
2017 Mallick R, Vakayil V, Lord A, McGonagill P, Chandrashekar M, Alsaied O, Gaertner WB, Khoruts A, Harmon J. Therapeutic Strategies for Severe and Severe-Complicated Clostridium Difficile Infection Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)34346-9  0.309
2017 Staley C, Hamilton MJ, Vaughn BP, Graiziger C, Newman KM, Kabage A, Sadowsky MJ, Khoruts A. Successful Resolution of Recurrent Clostridium Difficile Infection using Freeze-Dried, Encapsulated Fecal Microbiota Gastroenterology. 152: S343-S344. DOI: 10.1016/S0016-5085(17)31410-5  0.35
2016 Staley C, Kelly CR, Brandt LJ, Khoruts A, Sadowsky MJ. Complete Microbiota Engraftment Is Not Essential for Recovery from Recurrent Clostridium difficile Infection following Fecal Microbiota Transplantation. Mbio. 7. PMID 27999162 DOI: 10.1128/Mbio.01965-16  0.387
2016 Staley C, Vaughn BP, Graiziger CT, Sadowsky MJ, Khoruts A. Gut-sparing treatment of urinary tract infection in patients at high risk of Clostridium difficile infection. The Journal of Antimicrobial Chemotherapy. PMID 27999027 DOI: 10.1093/Jac/Dkw499  0.361
2016 Staley C, Weingarden AR, Khoruts A, Sadowsky MJ. Interaction of gut microbiota with bile acid metabolism and its influence on disease states. Applied Microbiology and Biotechnology. PMID 27888332 DOI: 10.1007/S00253-016-8006-6  0.733
2016 Sadowsky MJ, Khoruts A. Faecal microbiota transplantation is promising but not a panacea. Nature Microbiology. 1: 16015. PMID 27572174 DOI: 10.1038/Nmicrobiol.2016.15  0.407
2016 Kelly CR, Khoruts A, Staley C, Sadowsky MJ, Abd M, Alani M, Bakow B, Curran P, McKenney J, Tisch A, Reinert SE, Machan JT, Brandt LJ. Effect of Fecal Microbiota Transplantation on Recurrence in Multiply Recurrent Clostridium difficile Infection: A Randomized Trial. Annals of Internal Medicine. PMID 27547925 DOI: 10.7326/M16-0271  0.37
2016 Khoruts A, Hippen KL, Lemire AM, Holtan SG, Knights D, Young JH. Toward revision of antimicrobial therapies in hematopoietic stem cell transplantation: target the pathogens, but protect the indigenous microbiota. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 27513211 DOI: 10.1016/J.Trsl.2016.07.013  0.397
2016 Khoruts A, Sadowsky MJ. Understanding the mechanisms of faecal microbiota transplantation. Nature Reviews. Gastroenterology & Hepatology. PMID 27329806 DOI: 10.1038/Nrgastro.2016.98  0.419
2016 Khoruts A, Rank KM, Newman KM, Viskocil K, Vaughn BP, Hamilton MJ, Sadowsky MJ. Inflammatory Bowel Disease Affects the Outcome of Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 26905904 DOI: 10.1016/J.Cgh.2016.02.018  0.384
2016 Weingarden AR, Dosa PI, DeWinter E, Steer CJ, Shaughnessy MK, Johnson JR, Khoruts A, Sadowsky MJ. Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth. Plos One. 11: e0147210. PMID 26789728 DOI: 10.1371/Journal.Pone.0147210  0.747
2016 Khanna S, Vázquez-Baeza Y, González A, Weiss S, Schmidt B, Muñiz-Pedrogo D, Rainey JF, Kammer P, Nelson H, Sadowsky M, Khoruts A, Farrugia SL, Knight R, Pardi D, Kashyap P. Changes in Microbial Ecology After Fecal Microbiota Transplantation for Recurrent C. Difficile Infection Depends on Underlying Inflammatory Bowel Disease: 2016 ACG Presidential Poster Award American Journal of Gastroenterology. 111: S75. DOI: 10.14309/00000434-201610001-00159  0.391
2016 Khoruts A, Staley C, Vaughn BP, Graiziger C, Sadowsky MJ. Mo1290 Treatment of Urinary Tract Infections Without Affecting the Gut Microbiota in Patients With Recurrent Clostridium difficile Infection Gastroenterology. 150: S689. DOI: 10.1016/S0016-5085(16)32347-2  0.353
2016 Staley C, Kelly CR, Brandt LJ, Khoruts A, Sadowsky MJ. Su1743 Characterization of Fecal Microbiota in Response to Heterologous Versus Autologous (Placebo) Fecal Microbial Transplantation: Results From a Dual-Center, Randomized, Placebo-Controlled Trial Gastroenterology. 150: S542. DOI: 10.1016/S0016-5085(16)31860-1  0.306
2015 Weingarden AR, Chen C, Zhang N, Graiziger CT, Dosa PI, Steer CJ, Shaughnessy MK, Johnson JR, Sadowsky MJ, Khoruts A. Ursodeoxycholic Acid Inhibits Clostridium difficile Spore Germination and Vegetative Growth, and Prevents the Recurrence of Ileal Pouchitis Associated With the Infection. Journal of Clinical Gastroenterology. PMID 26485102 DOI: 10.1097/Mcg.0000000000000427  0.726
2015 Weingarden A, González A, Vázquez-Baeza Y, Weiss S, Humphry G, Berg-Lyons D, Knights D, Unno T, Bobr A, Kang J, Khoruts A, Knight R, Sadowsky MJ. Dynamic changes in short- and long-term bacterial composition following fecal microbiota transplantation for recurrent Clostridium difficile infection. Microbiome. 3: 10. PMID 25825673 DOI: 10.1186/S40168-015-0070-0  0.759
2015 Afrin LB, Khoruts A. Mast Cell Activation Disease and Microbiotic Interactions. Clinical Therapeutics. 37: 941-53. PMID 25773459 DOI: 10.1016/J.Clinthera.2015.02.008  0.32
2015 Rothenberger MK, Keele BF, Wietgrefe SW, Fletcher CV, Beilman GJ, Chipman JG, Khoruts A, Estes JD, Anderson J, Callisto SP, Schmidt TE, Thorkelson A, Reilly C, Perkey K, Reimann TG, et al. Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption. Proceedings of the National Academy of Sciences of the United States of America. 112: E1126-34. PMID 25713386 DOI: 10.1073/Pnas.1414926112  0.328
2015 Khoruts A, Sadowsky MJ, Hamilton MJ. Development of fecal microbiota transplantation suitable for mainstream medicine. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 13: 246-50. PMID 25460566 DOI: 10.1016/J.Cgh.2014.11.014  0.365
2015 Khoruts A, Rank KM, Viskocil K, Newman KM. Mo1862 Diagnostic Value of Colonoscopy in Patients Receiving Fecal Microbiota Transplantation in Treatment of Refractory Clostridium difficile Infection Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)32491-4  0.377
2014 Khoruts A, Weingarden AR. Emergence of fecal microbiota transplantation as an approach to repair disrupted microbial gut ecology. Immunology Letters. 162: 77-81. PMID 25106113 DOI: 10.1016/J.Imlet.2014.07.016  0.757
2014 Kelly CR, Ihunnah C, Fischer M, Khoruts A, Surawicz C, Afzali A, Aroniadis O, Barto A, Borody T, Giovanelli A, Gordon S, Gluck M, Hohmann EL, Kao D, Kao JY, et al. Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients. The American Journal of Gastroenterology. 109: 1065-71. PMID 24890442 DOI: 10.1038/Ajg.2014.133  0.331
2014 Shankar V, Hamilton MJ, Khoruts A, Kilburn A, Unno T, Paliy O, Sadowsky MJ. Species and genus level resolution analysis of gut microbiota in Clostridium difficile patients following fecal microbiota transplantation. Microbiome. 2: 13. PMID 24855561 DOI: 10.1186/2049-2618-2-13  0.416
2014 Petrof EO, Khoruts A. From stool transplants to next-generation microbiota therapeutics. Gastroenterology. 146: 1573-82. PMID 24412527 DOI: 10.1053/J.Gastro.2014.01.004  0.398
2014 Khoruts A. Faecal microbiota transplantation in 2013: developing human gut microbiota as a class of therapeutics. Nature Reviews. Gastroenterology & Hepatology. 11: 79-80. PMID 24296579 DOI: 10.1038/Nrgastro.2013.231  0.345
2014 Weingarden AR, Chen C, Bobr A, Yao D, Lu Y, Nelson VM, Sadowsky MJ, Khoruts A. Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G310-9. PMID 24284963 DOI: 10.1152/Ajpgi.00282.2013  0.753
2014 Kelly CR, Kunde SS, Khoruts A. Guidance on preparing an investigational new drug application for fecal microbiota transplantation studies. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 12: 283-8. PMID 24107393 DOI: 10.1016/J.Cgh.2013.09.060  0.342
2014 Sadowsky MJ, Weingarden A, Khoruts A, Gonzalez A, Vázquez-Baeza Y, Weiss S, Knight R, Unno T, Bobr A, Kang J. Tu1769 Short and Long Term Changes in Bacterial Composition Following Fecal Microbiota Transplantation for CDI Visualized in Movie Format Gastroenterology. 146: S-838. DOI: 10.1016/S0016-5085(14)63045-6  0.324
2013 Weingarden AR, Hamilton MJ, Sadowsky MJ, Khoruts A. Resolution of severe Clostridium difficile infection following sequential fecal microbiota transplantation. Journal of Clinical Gastroenterology. 47: 735-7. PMID 23632358 DOI: 10.1097/Mcg.0B013E31829004Ae  0.739
2013 Hamilton MJ, Weingarden AR, Unno T, Khoruts A, Sadowsky MJ. High-throughput DNA sequence analysis reveals stable engraftment of gut microbiota following transplantation of previously frozen fecal bacteria. Gut Microbes. 4: 125-35. PMID 23333862 DOI: 10.4161/Gmic.23571  0.759
2013 Ihunnah C, Khoruts A, Fischer M, Afzali A, Aroniadis O, Barto A, Borody T, Brandt L, Giovanelli A, Gordon S, Hohmann E, Kao D, Kao J, McQuillen D, Mellow M, et al. Fecal Microbiota Transplantation (FMT) for Treatment of Clostridium difficile Infection (CDI) in Immunocompromised Patients: ACG Governors Award for Excellence in Clinical Research: 611 The American Journal of Gastroenterology. 108. DOI: 10.14309/00000434-201310001-00611  0.376
2013 Weingarden A, Hamilton MJ, Sadowsky MJ, Khoruts A. Tu1714 Changes in Bacterial Composition Following Fecal Microbiota Transplantation for Severe Clostridium Difficie Infection Gastroenterology. 144: S-829. DOI: 10.1016/S0016-5085(13)63078-4  0.393
2012 Hamilton MJ, Weingarden AR, Sadowsky MJ, Khoruts A. Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection. The American Journal of Gastroenterology. 107: 761-7. PMID 22290405 DOI: 10.1038/Ajg.2011.482  0.751
2012 Borody TJ, Khoruts A. Fecal microbiota transplantation and emerging applications. Nature Reviews. Gastroenterology & Hepatology. 9: 88-96. PMID 22183182 DOI: 10.1038/Nrgastro.2011.244  0.368
2012 Khoruts A, Hamilton MJ, Weingarden A, Sadowsky MJ. Su1430 Treatment of C. Difficile by Fecal Transplantation Gastrointestinal Endoscopy. 75: AB329. DOI: 10.1016/J.Gie.2012.03.855  0.322
2011 Bakken JS, Borody T, Brandt LJ, Brill JV, Demarco DC, Franzos MA, Kelly C, Khoruts A, Louie T, Martinelli LP, Moore TA, Russell G, Surawicz C. Treating Clostridium difficile infection with fecal microbiota transplantation. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 9: 1044-9. PMID 21871249 DOI: 10.1016/J.Cgh.2011.08.014  0.408
2011 Khoruts A, Sadowsky MJ. Therapeutic transplantation of the distal gut microbiota Mucosal Immunology. 4: 4-7. PMID 21150894 DOI: 10.1038/Mi.2010.79  0.413
2010 Winstead CJ, Reilly CS, Moon JJ, Jenkins MK, Hamilton SE, Jameson SC, Way SS, Khoruts A. CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia. Journal of Immunology (Baltimore, Md. : 1950). 184: 4749-60. PMID 20357265 DOI: 10.4049/Jimmunol.0904076  0.778
2010 Wang B, Dileepan T, Briscoe S, Hyland KA, Kang J, Khoruts A, Cleary PP. Induction of TGF-beta1 and TGF-beta1-dependent predominant Th17 differentiation by group A streptococcal infection. Proceedings of the National Academy of Sciences of the United States of America. 107: 5937-42. PMID 20231435 DOI: 10.1073/Pnas.0904831107  0.34
2010 Khoruts A, Dicksved J, Jansson JK, Sadowsky MJ. Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-associated diarrhea. Journal of Clinical Gastroenterology. 44: 354-60. PMID 20048681 DOI: 10.1097/Mcg.0B013E3181C87E02  0.409
2008 Brenchley JM, Knox KS, Asher AI, Price DA, Kohli LM, Gostick E, Hill BJ, Hage CA, Brahmi Z, Khoruts A, Twigg HL, Schacker TW, Douek DC. High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage. Mucosal Immunology. 1: 49-58. PMID 19079160 DOI: 10.1038/Mi.2007.5  0.38
2008 Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi B, Asher TE, Scheinberg P, Price DA, Hage CA, Kholi LM, Khoruts A, Frank I, Else J, Schacker T, Silvestri G, et al. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood. 112: 2826-35. PMID 18664624 DOI: 10.1182/Blood-2008-05-159301  0.351
2008 Estes J, Baker JV, Brenchley JM, Khoruts A, Barthold JL, Bantle A, Reilly CS, Beilman GJ, George ME, Douek DC, Haase AT, Schacker TW. Collagen deposition limits immune reconstitution in the gut. The Journal of Infectious Diseases. 198: 456-64. PMID 18598193 DOI: 10.1086/590112  0.353
2008 Winstead CJ, Fraser JM, Khoruts A. Regulatory CD4+CD25+Foxp3+ T cells selectively inhibit the spontaneous form of lymphopenia-induced proliferation of naive T cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 7305-17. PMID 18490730 DOI: 10.4049/Jimmunol.180.11.7305  0.776
2008 Kang J, Huddleston SJ, Fraser JM, Khoruts A. De novo induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells in vivo following systemic antigen administration accompanied by blockade of mTOR. Journal of Leukocyte Biology. 83: 1230-9. PMID 18270248 DOI: 10.1189/Jlb.1207851  0.674
2007 Fischer UB, Jacovetty EL, Medeiros RB, Goudy BD, Zell T, Swanson JB, Lorenz E, Shimizu Y, Miller MJ, Khoruts A, Ingulli E. MHC class II deprivation impairs CD4 T cell motility and responsiveness to antigen-bearing dendritic cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 7181-6. PMID 17435166 DOI: 10.1073/Pnas.0608299104  0.364
2006 Hataye J, Moon JJ, Khoruts A, Reilly C, Jenkins MK. Naive and memory CD4+ T cell survival controlled by clonal abundance. Science (New York, N.Y.). 312: 114-6. PMID 16513943 DOI: 10.1126/Science.1124228  0.766
2005 Khoruts A, Fraser JM. A causal link between lymphopenia and autoimmunity. Immunology Letters. 98: 23-31. PMID 15790505 DOI: 10.1016/J.Imlet.2004.10.022  0.394
2005 Thorstenson KM, Herzovi L, Khoruts A. A model of suppression of the antigen-specific CD4 T cell response by regulatory CD25+CD4 T cells in vivo. International Immunology. 17: 335-42. PMID 15710910 DOI: 10.1093/Intimm/Dxh213  0.393
2004 Brenchley JM, Schacker TW, Ruff LE, Price DA, Taylor JH, Beilman GJ, Nguyen PL, Khoruts A, Larson M, Haase AT, Douek DC. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. The Journal of Experimental Medicine. 200: 749-59. PMID 15365096 DOI: 10.1084/Jem.20040874  0.384
2004 Hagen KA, Moses CT, Drasler EF, Podetz-Pedersen KM, Jameson SC, Khoruts A. A role for CD28 in lymphopenia-induced proliferation of CD4 T cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 3909-15. PMID 15356139 DOI: 10.4049/Jimmunol.173.6.3909  0.358
2004 Khoruts A, Osness RE, Jenkins MK. IL-1 acts on antigen-presenting cells to enhance the in vivo proliferation of antigen-stimulated naive CD4 T cells via a CD28-dependent mechanism that does not involve increased expression of CD28 ligands. European Journal of Immunology. 34: 1085-90. PMID 15048719 DOI: 10.1002/Eji.200324170  0.561
2003 Moses CT, Thorstenson KM, Jameson SC, Khoruts A. Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 1185-90. PMID 12525694 DOI: 10.1073/Pnas.0334572100  0.38
2001 Prlic M, Blazar BR, Khoruts A, Zell T, Jameson SC. Homeostatic expansion occurs independently of costimulatory signals. Journal of Immunology (Baltimore, Md. : 1950). 167: 5664-8. PMID 11698438 DOI: 10.4049/Jimmunol.167.10.5664  0.364
2001 Vanasek TL, Khoruts A, Zell T, Mueller DL. Antagonistic roles for CTLA-4 and the mammalian target of rapamycin in the regulation of clonal anergy: enhanced cell cycle progression promotes recall antigen responsiveness. Journal of Immunology (Baltimore, Md. : 1950). 167: 5636-44. PMID 11698435 DOI: 10.4049/Jimmunol.167.10.5636  0.351
2001 Zell T, Khoruts A, Ingulli E, Bonnevier JL, Mueller DL, Jenkins MK. Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo. Proceedings of the National Academy of Sciences of the United States of America. 98: 10805-10. PMID 11535838 DOI: 10.1073/Pnas.191567898  0.581
2001 Thorstenson KM, Khoruts A. Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. Journal of Immunology (Baltimore, Md. : 1950). 167: 188-95. PMID 11418648 DOI: 10.4049/Jimmunol.167.1.188  0.37
2001 Jenkins MK, Khoruts A, Ingulli E, Mueller DL, McSorley SJ, Reinhardt RL, Itano A, Pape KA. In vivo activation of antigen-specific CD4 T cells. Annual Review of Immunology. 19: 23-45. PMID 11244029 DOI: 10.1146/Annurev.Immunol.19.1.23  0.688
2001 Reinhardt RL, Khoruts A, Merica R, Zell T, Jenkins MK. Visualizing the generation of memory CD4 T cells in the whole body. Nature. 410: 101-5. PMID 11242050 DOI: 10.1038/35065111  0.692
2001 Khoruts A, Thorstenson KM. Generation of immunoregulatory CD25+CD4+T cells following induction of oral tolerance Gastroenterology. 120: A321. DOI: 10.1016/S0016-5085(08)81597-1  0.347
2000 Merica R, Khoruts A, Pape KA, Reinhardt RL, Jenkins MK. Antigen-experienced CD4 T cells display a reduced capacity for clonal expansion in vivo that is imposed by factors present in the immune host. Journal of Immunology (Baltimore, Md. : 1950). 164: 4551-7. PMID 10779756 DOI: 10.4049/Jimmunol.164.9.4551  0.688
1999 Shrikant P, Khoruts A, Mescher MF. CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism Immunity. 11: 483-493. PMID 10549630 DOI: 10.1016/S1074-7613(00)80123-5  0.362
1998 Pape KA, Khoruts A, Ingulli E, Mondino A, Merica R, Jenkins MK. Antigen-specific CD4+ T cells that survive after the induction of peripheral tolerance possess an intrinsic lymphokine production defect. Novartis Foundation Symposium. 215: 103-13; discussion 1. PMID 9760574 DOI: 10.1002/9780470515525.Ch8  0.558
1998 Khoruts A, Mondino A, Pape KA, Reiner SL, Jenkins MK. A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism. The Journal of Experimental Medicine. 187: 225-36. PMID 9432980 DOI: 10.1084/Jem.187.2.225  0.58
1997 Ingulli E, Mondino A, Khoruts A, Jenkins MK. In vivo detection of dendritic cell antigen presentation to CD4(+) T cells. The Journal of Experimental Medicine. 185: 2133-41. PMID 9182685 DOI: 10.1084/Jem.185.12.2133  0.569
1997 Pape KA, Kearney ER, Khoruts A, Mondino A, Merica R, Chen ZM, Ingulli E, White J, Johnson JG, Jenkins MK. Use of adoptive transfer of T-cell-antigen-receptor-transgenic T cell for the study of T-cell activation in vivo. Immunological Reviews. 156: 67-78. PMID 9176700 DOI: 10.1111/J.1600-065X.1997.Tb00959.X  0.591
1996 Mondino A, Khoruts A, Jenkins MK. The anatomy of T-cell activation and tolerance Proceedings of the National Academy of Sciences of the United States of America. 93: 2245-2252. PMID 8637857 DOI: 10.1073/Pnas.93.6.2245  0.589
1996 Khoruts A, Jenkins MK. Studying immunological tolerance by physically monitoring antigen-specific T cells in vivo Annals of the New York Academy of Sciences. 778: 72-79. PMID 8611018 DOI: 10.1111/J.1749-6632.1996.Tb21116.X  0.571
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