Radhakrishnan Padmanabhan - Publications

Affiliations: 
Microbiology & Immunology Georgetown University, Washington, DC 
Area:
Virology Biology, Microbiology Biology, Molecular Biology

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Balasubramanian A, Manzano M, Teramoto T, Pilankatta R, Padmanabhan R. High-throughput screening for the identification of small-molecule inhibitors of the flaviviral protease. Antiviral Research. PMID 27539384 DOI: 10.1016/J.Antiviral.2016.08.014  1
2016 Klema VJ, Ye M, Hindupur A, Teramoto T, Gottipati K, Padmanabhan R, Choi KH. Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface. Plos Pathogens. 12: e1005451. PMID 26895240 DOI: 10.1371/Journal.Ppat.1005451  1
2015 Klema VJ, Padmanabhan R, Choi KH. Flaviviral Replication Complex: Coordination between RNA Synthesis and 51-RNA Capping. Viruses. 7: 4640-56. PMID 26287232 DOI: 10.3390/V7082837  1
2015 Padmanabhan R, Takhampunya R, Teramoto T, Choi KH. Flavivirus RNA synthesis in vitro. Methods (San Diego, Calif.). PMID 26272247 DOI: 10.1016/J.Ymeth.2015.08.002  1
2015 Erkizan HV, Schneider JA, Sajwan K, Graham GT, Griffin B, Chasovskikh S, Youbi SE, Kallarakal A, Chruszcz M, Padmanabhan R, Casey JL, Üren A, Toretsky JA. RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1. Nucleic Acids Research. 43: 1069-80. PMID 25564528 DOI: 10.1093/Nar/Gku1328  1
2014 Teramoto T, Boonyasuppayakorn S, Handley M, Choi KH, Padmanabhan R. Substitution of NS5 N-terminal domain of dengue virus type 2 RNA with type 4 domain caused impaired replication and emergence of adaptive mutants with enhanced fitness. The Journal of Biological Chemistry. 289: 22385-400. PMID 24904061 DOI: 10.1074/Jbc.M114.584466  1
2014 Boonyasuppayakorn S, Padmanabhan R. Construction of plasmid, bacterial expression, purification, and assay of dengue virus type 2 NS5 methyltransferase. Methods in Molecular Biology (Clifton, N.J.). 1138: 361-73. PMID 24696348 DOI: 10.1007/978-1-4939-0348-1_22  1
2014 Lai H, Teramoto T, Padmanabhan R. Construction of dengue virus protease expression plasmid and in vitro protease assay for screening antiviral inhibitors. Methods in Molecular Biology (Clifton, N.J.). 1138: 345-60. PMID 24696347 DOI: 10.1007/978-1-4939-0348-1_21  1
2014 Manzano M, Padia J, Padmanabhan R. Small molecule inhibitor discovery for dengue virus protease using high-throughput screening. Methods in Molecular Biology (Clifton, N.J.). 1138: 331-44. PMID 24696346 DOI: 10.1007/978-1-4939-0348-1_20  0.4
2014 Manzano M, Padmanabhan R. Targeted mutagenesis of dengue virus type 2 replicon RNA by yeast in vivo recombination. Methods in Molecular Biology (Clifton, N.J.). 1138: 151-60. PMID 24696336 DOI: 10.1007/978-1-4939-0348-1_10  0.4
2014 Alcaraz-Estrada SL, Del Angel R, Padmanabhan R. Construction of self-replicating subgenomic dengue virus 4 (DENV4) replicon. Methods in Molecular Biology (Clifton, N.J.). 1138: 131-50. PMID 24696335 DOI: 10.1007/978-1-4939-0348-1_9  0.32
2014 Boonyasuppayakorn S, Reichert ED, Manzano M, Nagarajan K, Padmanabhan R. Amodiaquine, an antimalarial drug, inhibits dengue virus type 2 replication and infectivity. Antiviral Research. 106: 125-34. PMID 24680954 DOI: 10.1016/J.Antiviral.2014.03.014  1
2013 Alcaraz-Estrada SL, Reichert ED, Padmanabhan R. Construction of self-replicating subgenomic West Nile virus replicons for screening antiviral compounds. Methods in Molecular Biology (Clifton, N.J.). 1030: 283-99. PMID 23821276 DOI: 10.1007/978-1-62703-484-5_22  1
2013 Teramoto T, Chiang HS, Takhampunya R, Manzano M, Padmanabhan R, Maric M. Gamma interferon-inducible lysosomal thioreductase (GILT) ablation renders mouse fibroblasts sensitive to dengue virus replication. Virology. 441: 146-51. PMID 23642353 DOI: 10.1016/J.Virol.2013.03.017  1
2013 Sztuba-Solinska J, Teramoto T, Rausch JW, Shapiro BA, Padmanabhan R, Le Grice SF. Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome. Nucleic Acids Research. 41: 5075-89. PMID 23531545 DOI: 10.1093/Nar/Gkt203  1
2013 Lai H, Dou D, Aravapalli S, Teramoto T, Lushington GH, Mwania TM, Alliston KR, Eichhorn DM, Padmanabhan R, Groutas WC. Design, synthesis and characterization of novel 1,2-benzisothiazol-3(2H)-one and 1,3,4-oxadiazole hybrid derivatives: potent inhibitors of Dengue and West Nile virus NS2B/NS3 proteases. Bioorganic & Medicinal Chemistry. 21: 102-13. PMID 23211969 DOI: 10.1016/J.Bmc.2012.10.058  1
2013 Lai H, Sridhar Prasad G, Padmanabhan R. Characterization of 8-hydroxyquinoline derivatives containing aminobenzothiazole as inhibitors of dengue virus type 2 protease in vitro. Antiviral Research. 97: 74-80. PMID 23127365 DOI: 10.1016/J.Antiviral.2012.10.009  1
2012 Ezgimen M, Lai H, Mueller NH, Lee K, Cuny G, Ostrov DA, Padmanabhan R. Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease. Antiviral Research. 94: 18-24. PMID 22343093 DOI: 10.1016/J.Antiviral.2012.02.003  1
2012 Tiew KC, Dou D, Teramoto T, Lai H, Alliston KR, Lushington GH, Padmanabhan R, Groutas WC. Inhibition of Dengue virus and West Nile virus proteases by click chemistry-derived benz[d]isothiazol-3(2H)-one derivatives. Bioorganic & Medicinal Chemistry. 20: 1213-21. PMID 22249124 DOI: 10.1016/J.Bmc.2011.12.047  1
2011 Manzano M, Reichert ED, Polo S, Falgout B, Kasprzak W, Shapiro BA, Padmanabhan R. Identification of cis-acting elements in the 3'-untranslated region of the dengue virus type 2 RNA that modulate translation and replication. The Journal of Biological Chemistry. 286: 22521-34. PMID 21515677 DOI: 10.1074/Jbc.M111.234302  1
2010 Wu R, Smidansky ED, Oh HS, Takhampunya R, Padmanabhan R, Cameron CE, Peterson BR. Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses. Journal of Medicinal Chemistry. 53: 7958-66. PMID 20964406 DOI: 10.1021/Jm100593S  1
2010 Dou D, Viwanathan P, Li Y, He G, Alliston KR, Lushington GH, Brown-Clay JD, Padmanabhan R, Groutas WC. Design, synthesis, and in vitro evaluation of potential West Nile virus protease inhibitors based on the 1-oxo-1,2,3,4-tetrahydroisoquinoline and 1-oxo-1,2-dihydroisoquinoline scaffolds. Journal of Combinatorial Chemistry. 12: 836-43. PMID 20882963 DOI: 10.1021/Cc100091H  1
2010 Alcaraz-Estrada SL, Manzano MI, Del Angel RM, Levis R, Padmanabhan R. Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5. The Journal of General Virology. 91: 2713-8. PMID 20631089 DOI: 10.1099/Vir.0.024083-0  1
2009 Ezgimen MD, Mueller NH, Teramoto T, Padmanabhan R. Effects of detergents on the West Nile virus protease activity Bioorganic and Medicinal Chemistry. 17: 3278-3282. PMID 19369080 DOI: 10.1016/J.Bmc.2009.03.050  1
2009 Sampath A, Padmanabhan R. Molecular targets for flavivirus drug discovery Antiviral Research. 81: 6-15. PMID 18796313 DOI: 10.1016/J.Antiviral.2008.08.004  1
2008 Teramoto T, Kohno Y, Mattoo P, Markoff L, Falgout B, Padmanabhan R. Genome 3'-end repair in dengue virus type 2. Rna (New York, N.Y.). 14: 2645-56. PMID 18974278 DOI: 10.1261/Rna.1051208  1
2008 Mueller NH, Pattabiraman N, Ansarah-Sobrinho C, Viswanathan P, Pierson TC, Padmanabhan R. Identification and biochemical characterization of small-molecule inhibitors of west nile virus serine protease by a high-throughput screen. Antimicrobial Agents and Chemotherapy. 52: 3385-93. PMID 18606844 DOI: 10.1016/J.Antiviral.2007.01.016  1
2008 Yu L, Nomaguchi M, Padmanabhan R, Markoff L. Specific requirements for elements of the 5′ and 3′ terminal regions in flavivirus RNA synthesis and viral replication Virology. 374: 170-185. PMID 18234265 DOI: 10.1016/J.Virol.2007.12.035  1
2008 Padmanabhan R, Mueller N, Reichert E, Yon C, Teramoto T, Kono Y, Takhampunya R, Ubol S, Pattabiraman N, Falgout B, Ganesh VK, Murthy K. Multiple Enzyme Activities of Flavivirus Proteins New Treatment Strategies For Dengue and Other Flaviviral Diseases. 74-86. DOI: 10.1002/0470058005.ch6  1
2007 Mueller NH, Yon C, Ganesh VK, Padmanabhan R. Characterization of the West Nile virus protease substrate specificity and inhibitors International Journal of Biochemistry and Cell Biology. 39: 606-614. PMID 17188926 DOI: 10.1016/J.Biocel.2006.10.025  1
2007 Palmer DR, Fernandez S, Bisbing J, Peachman KK, Rao M, Barvir D, Gunther V, Burgess T, Kohno Y, Padmanabhan R, Sun W. Restricted replication and lysosomal trafficking of yellow fever 17D vaccine virus in human dendritic cells. The Journal of General Virology. 88: 148-56. PMID 17170447 DOI: 10.1099/Vir.0.82272-0  1
2007 Yocupicio-Monroy M, Padmanabhan R, Medina F, del Angel RM. Mosquito La protein binds to the 3′ untranslated region of the positive and negative polarity dengue virus RNAs and relocates to the cytoplasm of infected cells Virology. 357: 29-40. PMID 16962153 DOI: 10.1016/J.Virol.2006.07.042  1
2006 Takhampunya R, Padmanabhan R, Ubol S. Antiviral action of nitric oxide on dengue virus type 2 replication Journal of General Virology. 87: 3003-3011. PMID 16963759 DOI: 10.1099/Vir.0.81880-0  1
2006 Takhampunya R, Ubol S, Houng HS, Cameron CE, Padmanabhan R. Inhibition of dengue virus replication by mycophenolic acid and ribavirin. The Journal of General Virology. 87: 1947-52. PMID 16760396 DOI: 10.1099/Vir.0.81655-0  1
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