Larry Schlesinger - Publications

Affiliations: 
Integrated Biomedical Sciences Ohio State University, Columbus, Columbus, OH 
Area:
Molecular Biology, Microbiology Biology

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Moliva JI, Duncan MA, Olmo-Fontánez A, Akhter A, Arnett E, Scordo JM, Ault R, Sasindran SJ, Azad AK, Montoya MJ, Reinhold-Larsson N, Rajaram MVS, Merrit RE, Lafuse WP, Zhang L, ... ... Schlesinger LS, et al. The lung mucosa environment in the elderly increases host susceptibility to Mycobacterium tuberculosis infection. The Journal of Infectious Diseases. PMID 30923818 DOI: 10.1093/infdis/jiz138  0.36
2018 Johnson MM, Collier MA, Hoang KV, Pino EN, Graham-Gurysh EG, Gallovic MD, Zahid MSH, Chen N, Schlesinger L, Gunn JS, Bachelder EM, Ainslie KM. In vivo and Cellular Trafficking of Acetalated Dextran Microparticles for Delivery of a Host-Directed Therapy for Salmonella enterica Serovar Typhi Infection. Molecular Pharmaceutics. PMID 30296381 DOI: 10.1021/acs.molpharmaceut.8b00802  0.44
2018 Guirado E, Rajaram MV, Chawla A, Daigle J, La Perle KM, Arnett E, Turner J, Schlesinger LS. Deletion of PPARγ in lung macrophages provides an immunoprotective response against M. tuberculosis infection in mice. Tuberculosis (Edinburgh, Scotland). 111: 170-177. PMID 30029904 DOI: 10.1016/j.tube.2018.06.012  0.32
2018 Arnett E, Weaver AM, Woodyard KC, Montoya MJ, Li M, Hoang KV, Hayhurst A, Azad AK, Schlesinger LS. PPARγ is critical for Mycobacterium tuberculosis induction of Mcl-1 and limitation of human macrophage apoptosis. Plos Pathogens. 14: e1007100. PMID 29928066 DOI: 10.1371/journal.ppat.1007100  0.32
2018 Papp AC, Azad AK, Pietrzak M, Williams A, Handelman SK, Igo RP, Stein CM, Hartmann K, Schlesinger LS, Sadee W. AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection. Plos One. 13: e0198221. PMID 29847580 DOI: 10.1371/journal.pone.0198221  0.32
2018 Hoang KV, Rajaram MVS, Curry HM, Gavrilin MA, Wewers MD, Schlesinger LS. Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Phagocytosis by Human Mononuclear Phagocytes. Frontiers in Immunology. 9: 561. PMID 29632532 DOI: 10.3389/fimmu.2018.00561  0.36
2018 Garfoot AL, Goughenour KD, Wüthrich M, Rajaram MVS, Schlesinger LS, Klein BS, Rappleye CA. O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures. Mbio. 9. PMID 29295913 DOI: 10.1128/mBio.02121-17  0.36
2017 Pyle CJ, Azad AK, Papp AC, Sadee W, Knoell DL, Schlesinger LS. Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosis. International Journal of Molecular Sciences. 18. PMID 29120360 DOI: 10.3390/ijms18112375  0.32
2017 Rajaram MVS, Arnett E, Azad AK, Guirado E, Ni B, Gerberick AD, He LZ, Keler T, Thomas LJ, Lafuse WP, Schlesinger LS. M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1. Cell Reports. 21: 126-140. PMID 28978467 DOI: 10.1016/j.celrep.2017.09.034  0.36
2017 Hoang KV, Adcox HE, Fitch JR, Gordon DM, Curry HM, Schlesinger LS, White P, Gunn JS. AR-13, a Celecoxib Derivative, Directly Kills Francisella In Vitro and Aids Clearance and Mouse Survival In Vivo. Frontiers in Microbiology. 8: 1695. PMID 28955308 DOI: 10.3389/fmicb.2017.01695  0.44
2016 Makara MA, Hoang KV, Ganesan LP, Crouser ED, Gunn JS, Turner J, Schlesinger LS, Mohler PJ, Rajaram MV. Cardiac Electrical and Structural Changes During Bacterial Infection: An Instructive Model to Study Cardiac Dysfunction in Sepsis. Journal of the American Heart Association. 5. PMID 27620887 DOI: 10.1161/JAHA.116.003820  0.44
2016 Xiao Y, Tang J, Guo H, Zhao Y, Tang R, Ouyang S, Zeng Q, Rappleye CA, Rajaram MV, Schlesinger LS, Tao L, Brown GD, Langdon WY, Li BT, Zhang J. Targeting CBLB as a potential therapeutic approach for disseminated candidiasis. Nature Medicine. PMID 27428899 DOI: 10.1038/nm.4141  0.36
2016 Hoang KV, Curry H, Collier MA, Borteh H, Bachelder EM, Schlesinger LS, Gunn JS, Ainslie KM. Needle-Free Delivery of Acetalated Dextran-Encapsulated AR-12 Protects Mice from Francisella tularensis Lethal Challenge. Antimicrobial Agents and Chemotherapy. 60: 2052-62. PMID 26787696 DOI: 10.1128/AAC.02228-15  0.36
2015 Azad AK, Rajaram MV, Metz WL, Cope FO, Blue MS, Vera DR, Schlesinger LS. γ-Tilmanocept, a New Radiopharmaceutical Tracer for Cancer Sentinel Lymph Nodes, Binds to the Mannose Receptor (CD206). Journal of Immunology (Baltimore, Md. : 1950). 195: 2019-29. PMID 26202986 DOI: 10.4049/jimmunol.1402005  0.36
2015 Mishra M, Ressler A, Schlesinger LS, Wozniak DJ. Identification of OprF as a Complement Component C3 Binding Acceptor Molecule on the Surface of Pseudomonas aeruginosa. Infection and Immunity. 83: 3006-14. PMID 25964476 DOI: 10.1128/IAI.00081-15  0.36
2015 Salunke SB, Azad AK, Kapuriya NP, Balada-Llasat JM, Pancholi P, Schlesinger LS, Chen CS. Design and synthesis of novel anti-tuberculosis agents from the celecoxib pharmacophore. Bioorganic & Medicinal Chemistry. 23: 1935-43. PMID 25818768 DOI: 10.1016/j.bmc.2015.03.041  0.36
2015 Landes MB, Rajaram MV, Nguyen H, Schlesinger LS. Role for NOD2 in Mycobacterium tuberculosis-induced iNOS expression and NO production in human macrophages. Journal of Leukocyte Biology. 97: 1111-9. PMID 25801769 DOI: 10.1189/jlb.3A1114-557R  0.36
2015 Guirado E, Mbawuike U, Keiser TL, Arcos J, Azad AK, Wang SH, Schlesinger LS. Characterization of host and microbial determinants in individuals with latent tuberculosis infection using a human granuloma model. Mbio. 6: e02537-14. PMID 25691598 DOI: 10.1128/mBio.02537-14  0.36
2015 Pasula R, Azad AK, Gardner JC, Schlesinger LS, McCormack FX. Keratinocyte growth factor administration attenuates murine pulmonary mycobacterium tuberculosis infection through granulocyte-macrophage colony-stimulating factor (GM-CSF)-dependent macrophage activation and phagolysosome fusion. The Journal of Biological Chemistry. 290: 7151-9. PMID 25605711 DOI: 10.1074/jbc.M114.591891  0.36
2014 Rajaram MV, Ni B, Dodd CE, Schlesinger LS. Macrophage immunoregulatory pathways in tuberculosis. Seminars in Immunology. 26: 471-85. PMID 25453226 DOI: 10.1016/j.smim.2014.09.010  0.36
2014 Hoang KV, Borteh HM, Rajaram MV, Peine KJ, Curry H, Collier MA, Homsy ML, Bachelder EM, Gunn JS, Schlesinger LS, Ainslie KM. Acetalated dextran encapsulated AR-12 as a host-directed therapy to control Salmonella infection. International Journal of Pharmaceutics. 477: 334-43. PMID 25447826 DOI: 10.1016/j.ijpharm.2014.10.022  0.36
2014 Gebreyes WA, Dupouy-Camet J, Newport MJ, Oliveira CJ, Schlesinger LS, Saif YM, Kariuki S, Saif LJ, Saville W, Wittum T, Hoet A, Quessy S, Kazwala R, Tekola B, Shryock T, et al. The global one health paradigm: challenges and opportunities for tackling infectious diseases at the human, animal, and environment interface in low-resource settings. Plos Neglected Tropical Diseases. 8: e3257. PMID 25393303 DOI: 10.1371/journal.pntd.0003257  0.36
2014 Chesarino NM, Hach JC, Chen JL, Zaro BW, Rajaram MV, Turner J, Schlesinger LS, Pratt MR, Hang HC, Yount JS. Chemoproteomics reveals Toll-like receptor fatty acylation. Bmc Biology. 12: 91. PMID 25371237 DOI: 10.1186/s12915-014-0091-3  0.36
2014 Ni B, Rajaram MV, Lafuse WP, Landes MB, Schlesinger LS. Mycobacterium tuberculosis decreases human macrophage IFN-γ responsiveness through miR-132 and miR-26a. Journal of Immunology (Baltimore, Md. : 1950). 193: 4537-47. PMID 25252958 DOI: 10.4049/jimmunol.1400124  0.36
2014 Restrepo BI, Schlesinger LS. Impact of diabetes on the natural history of tuberculosis. Diabetes Research and Clinical Practice. 106: 191-9. PMID 25082309 DOI: 10.1016/j.diabres.2014.06.011  0.36
2014 Canan CH, Gokhale NS, Carruthers B, Lafuse WP, Schlesinger LS, Torrelles JB, Turner J. Characterization of lung inflammation and its impact on macrophage function in aging. Journal of Leukocyte Biology. 96: 473-80. PMID 24935957 DOI: 10.1189/jlb.4A0214-093RR  0.36
2014 Azad AK, Rajaram MV, Schlesinger LS. Exploitation of the Macrophage Mannose Receptor (CD206) in Infectious Disease Diagnostics and Therapeutics. Journal of Cytology & Molecular Biology. 1. PMID 24672807 DOI: 10.13188/2325-4653.1000003  0.32
2014 Restrepo BI, Twahirwa M, Rahbar MH, Schlesinger LS. Phagocytosis via complement or Fc-gamma receptors is compromised in monocytes from type 2 diabetes patients with chronic hyperglycemia. Plos One. 9: e92977. PMID 24671137 DOI: 10.1371/journal.pone.0092977  0.36
2014 Moliva JI, Rajaram MV, Sidiki S, Sasindran SJ, Guirado E, Pan XJ, Wang SH, Ross P, Lafuse WP, Schlesinger LS, Turner J, Torrelles JB. Molecular composition of the alveolar lining fluid in the aging lung. Age (Dordrecht, Netherlands). 36: 9633. PMID 24584696 DOI: 10.1007/s11357-014-9633-4  0.36
2014 Young NA, Wu LC, Burd CJ, Friedman AK, Kaffenberger BH, Rajaram MV, Schlesinger LS, James H, Shupnik MA, Jarjour WN. Estrogen modulation of endosome-associated toll-like receptor 8: an IFNα-independent mechanism of sex-bias in systemic lupus erythematosus. Clinical Immunology (Orlando, Fla.). 151: 66-77. PMID 24525049 DOI: 10.1016/j.clim.2014.01.006  0.36
2014 Hansen JM, Golchin SA, Veyrier FJ, Domenech P, Boneca IG, Azad AK, Rajaram MV, Schlesinger LS, Divangahi M, Reed MB, Behr MA. N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis. The Journal of Infectious Diseases. 209: 1045-54. PMID 24265438 DOI: 10.1093/infdis/jit622  0.36
2013 Stew SS, Martinez PJ, Schlesinger LS, Restrepo BI. Differential expression of monocyte surface markers among TB patients with diabetes co-morbidity. Tuberculosis (Edinburgh, Scotland). 93: S78-82. PMID 24388654 DOI: 10.1016/S1472-9792(13)70015-5  0.36
2013 Restrepo BI, Schlesinger LS. Host-pathogen interactions in tuberculosis patients with type 2 diabetes mellitus. Tuberculosis (Edinburgh, Scotland). 93: S10-4. PMID 24388642 DOI: 10.1016/S1472-9792(13)70004-0  0.36
2013 Collier MA, Gallovic MD, Peine KJ, Duong AD, Bachelder EM, Gunn JS, Schlesinger LS, Ainslie KM. Delivery of host cell-directed therapeutics for intracellular pathogen clearance. Expert Review of Anti-Infective Therapy. 11: 1225-35. PMID 24134600 DOI: 10.1586/14787210.2013.845524  0.36
2013 Guirado E, Schlesinger LS, Kaplan G. Macrophages in tuberculosis: friend or foe. Seminars in Immunopathology. 35: 563-83. PMID 23864058 DOI: 10.1007/s00281-013-0388-2  0.32
2013 Guirado E, Schlesinger LS. Modeling the Mycobacterium tuberculosis Granuloma - the Critical Battlefield in Host Immunity and Disease. Frontiers in Immunology. 4: 98. PMID 23626591 DOI: 10.3389/fimmu.2013.00098  0.32
2013 Yang L, Sinha T, Carlson TK, Keiser TL, Torrelles JB, Schlesinger LS. Changes in the major cell envelope components of Mycobacterium tuberculosis during in vitro growth. Glycobiology. 23: 926-34. PMID 23576535 DOI: 10.1093/glycob/cwt029  0.36
2013 Khweek AA, Caution K, Akhter A, Abdulrahman BA, Tazi M, Hassan H, Majumdar N, Doran A, Guirado E, Schlesinger LS, Shuman H, Amer AO. A bacterial protein promotes the recognition of the Legionella pneumophila vacuole by autophagy. European Journal of Immunology. 43: 1333-44. PMID 23420491 DOI: 10.1002/eji.201242835  0.36
2013 Dai S, Rajaram MV, Curry HM, Leander R, Schlesinger LS. Fine tuning inflammation at the front door: macrophage complement receptor 3-mediates phagocytosis and immune suppression for Francisella tularensis. Plos Pathogens. 9: e1003114. PMID 23359218 DOI: 10.1371/journal.ppat.1003114  0.36
2013 Young NA, Friedman AK, Kaffenberger B, Rajaram MV, Birmingham DJ, Rovin BH, Hebert LA, Schlesinger LS, Wu LC, Jarjour WN. Novel estrogen target gene ZAS3 is overexpressed in systemic lupus erythematosus. Molecular Immunology. 54: 23-31. PMID 23178823 DOI: 10.1016/j.molimm.2012.10.026  0.36
2013 Gomez DI, Twahirwa M, Schlesinger LS, Restrepo BI. Reduced Mycobacterium tuberculosis association with monocytes from diabetes patients that have poor glucose control. Tuberculosis (Edinburgh, Scotland). 93: 192-7. PMID 23131496 DOI: 10.1016/j.tube.2012.10.003  0.36
2013 Julian MW, Shao G, Schlesinger LS, Huang Q, Cosmar DG, Bhatt NY, Culver DA, Baughman RP, Wood KL, Crouser ED. Nicotine treatment improves Toll-like receptor 2 and Toll-like receptor 9 responsiveness in active pulmonary sarcoidosis. Chest. 143: 461-70. PMID 22878868 DOI: 10.1378/chest.12-0383  0.36
2012 Guirado E, Arcos J, Knaup R, Reeder R, Betz B, Cotton C, Patel T, Pfaller S, Torrelles JB, Schlesinger LS. Characterization of clinical and environmental Mycobacterium avium spp. isolates and their interaction with human macrophages. Plos One. 7: e45411. PMID 23028991 DOI: 10.1371/journal.pone.0045411  0.32
2012 Cremer TJ, Fatehchand K, Shah P, Gillette D, Patel H, Marsh RL, Besecker BY, Rajaram MV, Cormet-Boyaka E, Kanneganti TD, Schlesinger LS, Butchar JP, Tridandapani S. MiR-155 induction by microbes/microbial ligands requires NF-κB-dependent de novo protein synthesis. Frontiers in Cellular and Infection Microbiology. 2: 73. PMID 22919664 DOI: 10.3389/fcimb.2012.00073  0.36
2012 Nguyen HA, Rajaram MV, Meyer DA, Schlesinger LS. Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L608-16. PMID 22886503 DOI: 10.1152/ajplung.00067.2012  0.36
2012 Azad AK, Sadee W, Schlesinger LS. Innate immune gene polymorphisms in tuberculosis. Infection and Immunity. 80: 3343-59. PMID 22825450 DOI: 10.1128/IAI.00443-12  0.36
2012 Akhter A, Caution K, Abu Khweek A, Tazi M, Abdulrahman BA, Abdelaziz DH, Voss OH, Doseff AI, Hassan H, Azad AK, Schlesinger LS, Wewers MD, Gavrilin MA, Amer AO. Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization. Immunity. 37: 35-47. PMID 22658523 DOI: 10.1016/j.immuni.2012.05.001  0.36
2012 Dai S, Mohapatra NP, Schlesinger LS, Gunn JS. The acid phosphatase AcpA is secreted in vitro and in macrophages by Francisella spp. Infection and Immunity. 80: 1088-97. PMID 22184418 DOI: 10.1128/IAI.06245-11  0.36
2012 Mishra M, Byrd MS, Sergeant S, Azad AK, Parsek MR, McPhail L, Schlesinger LS, Wozniak DJ. Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization. Cellular Microbiology. 14: 95-106. PMID 21951860 DOI: 10.1111/j.1462-5822.2011.01704.x  0.36
2011 Abdulrahman BA, Khweek AA, Akhter A, Caution K, Kotrange S, Abdelaziz DH, Newland C, Rosales-Reyes R, Kopp B, McCoy K, Montione R, Schlesinger LS, Gavrilin MA, Wewers MD, Valvano MA, et al. Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis. Autophagy. 7: 1359-70. PMID 21997369 DOI: 10.4161/auto.7.11.17660  0.36
2011 Rajaram MV, Ni B, Morris JD, Brooks MN, Carlson TK, Bakthavachalu B, Schoenberg DR, Torrelles JB, Schlesinger LS. Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b. Proceedings of the National Academy of Sciences of the United States of America. 108: 17408-13. PMID 21969554 DOI: 10.1073/pnas.1112660108  0.36
2011 Keiser TL, Azad AK, Guirado E, Bonacci R, Schlesinger LS. Comparative transcriptional study of the putative mannose donor biosynthesis genes in virulent Mycobacterium tuberculosis and attenuated Mycobacterium bovis BCG strains. Infection and Immunity. 79: 4668-73. PMID 21896775 DOI: 10.1128/IAI.05635-11  0.32
2011 Torrelles JB, Sieling PA, Arcos J, Knaup R, Bartling C, Rajaram MV, Stenger S, Modlin RL, Schlesinger LS. Structural differences in lipomannans from pathogenic and nonpathogenic mycobacteria that impact CD1b-restricted T cell responses. The Journal of Biological Chemistry. 286: 35438-46. PMID 21859718 DOI: 10.1074/jbc.M111.232587  0.36
2011 Betz BE, Azad AK, Morris JD, Rajaram MV, Schlesinger LS. β-Glucans inhibit intracellular growth of Mycobacterium bovis BCG but not virulent Mycobacterium tuberculosis in human macrophages. Microbial Pathogenesis. 51: 233-42. PMID 21762773 DOI: 10.1016/j.micpath.2011.06.006  0.36
2011 Arcos J, Sasindran SJ, Fujiwara N, Turner J, Schlesinger LS, Torrelles JB. Human lung hydrolases delineate Mycobacterium tuberculosis-macrophage interactions and the capacity to control infection. Journal of Immunology (Baltimore, Md. : 1950). 187: 372-81. PMID 21602490 DOI: 10.4049/jimmunol.1100823  0.32
2011 Sow FB, Nandakumar S, Velu V, Kellar KL, Schlesinger LS, Amara RR, Lafuse WP, Shinnick TM, Sable SB. Mycobacterium tuberculosis components stimulate production of the antimicrobial peptide hepcidin. Tuberculosis (Edinburgh, Scotland). 91: 314-21. PMID 21482189 DOI: 10.1016/j.tube.2011.03.003  0.36
2011 Dwivedi V, Manickam C, Patterson R, Dodson K, Murtaugh M, Torrelles JB, Schlesinger LS, Renukaradhya GJ. Cross-protective immunity to porcine reproductive and respiratory syndrome virus by intranasal delivery of a live virus vaccine with a potent adjuvant. Vaccine. 29: 4058-66. PMID 21419162 DOI: 10.1016/j.vaccine.2011.03.006  0.36
2011 Brooks MN, Rajaram MV, Azad AK, Amer AO, Valdivia-Arenas MA, Park JH, Núñez G, Schlesinger LS. NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages. Cellular Microbiology. 13: 402-18. PMID 21040358 DOI: 10.1111/j.1462-5822.2010.01544.x  0.36
2010 Dai S, Mohapatra NP, Schlesinger LS, Gunn JS. Regulation of francisella tularensis virulence. Frontiers in Microbiology. 1: 144. PMID 21687801 DOI: 10.3389/fmicb.2010.00144  0.36
2010 Wang SH, Powell DA, Nagaraja HN, Morris JD, Schlesinger LS, Turner J. Evaluation of a modified interferon-gamma release assay for the diagnosis of latent tuberculosis infection in adult and paediatric populations that enables delayed processing. Scandinavian Journal of Infectious Diseases. 42: 845-50. PMID 20608764 DOI: 10.3109/00365548.2010.498021  0.36
2010 Rajaram MV, Brooks MN, Morris JD, Torrelles JB, Azad AK, Schlesinger LS. Mycobacterium tuberculosis activates human macrophage peroxisome proliferator-activated receptor gamma linking mannose receptor recognition to regulation of immune responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 929-42. PMID 20554962 DOI: 10.4049/jimmunol.1000866  0.36
2010 Mohapatra NP, Soni S, Rajaram MV, Dang PM, Reilly TJ, El-Benna J, Clay CD, Schlesinger LS, Gunn JS. Francisella acid phosphatases inactivate the NADPH oxidase in human phagocytes. Journal of Immunology (Baltimore, Md. : 1950). 184: 5141-50. PMID 20348422 DOI: 10.4049/jimmunol.0903413  0.36
2010 Sweet L, Singh PP, Azad AK, Rajaram MV, Schlesinger LS, Schorey JS. Mannose receptor-dependent delay in phagosome maturation by Mycobacterium avium glycopeptidolipids. Infection and Immunity. 78: 518-26. PMID 19841083 DOI: 10.1128/IAI.00257-09  0.36
2009 Cremer TJ, Ravneberg DH, Clay CD, Piper-Hunter MG, Marsh CB, Elton TS, Gunn JS, Amer A, Kanneganti TD, Schlesinger LS, Butchar JP, Tridandapani S. MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response. Plos One. 4: e8508. PMID 20041145 DOI: 10.1371/journal.pone.0008508  0.36
2009 Chiu HC, Soni S, Kulp SK, Curry H, Wang D, Gunn JS, Schlesinger LS, Chen CS. Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent. Journal of Biomedical Science. 16: 110. PMID 20003180 DOI: 10.1186/1423-0127-16-110  0.44
2009 Rajaram MV, Butchar JP, Parsa KV, Cremer TJ, Amer A, Schlesinger LS, Tridandapani S. Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway. Plos One. 4: e7919. PMID 19936232 DOI: 10.1371/journal.pone.0007919  0.36
2009 Chiu HC, Kulp SK, Soni S, Wang D, Gunn JS, Schlesinger LS, Chen CS. Eradication of intracellular Salmonella enterica serovar Typhimurium with a small-molecule, host cell-directed agent. Antimicrobial Agents and Chemotherapy. 53: 5236-44. PMID 19805568 DOI: 10.1128/AAC.00555-09  0.44
2009 Carlson TK, Torrelles JB, Smith K, Horlacher T, Castelli R, Seeberger PH, Crouch EC, Schlesinger LS. Critical role of amino acid position 343 of surfactant protein-D in the selective binding of glycolipids from Mycobacterium tuberculosis. Glycobiology. 19: 1473-84. PMID 19684355 DOI: 10.1093/glycob/cwp122  0.36
2009 Wang SH, Pancholi P, Stevenson K, Yakrus MA, Butler WR, Schlesinger LS, Mangino JE. Pseudo-outbreak of "Mycobacterium paraffinicum" infection and/or colonization in a tertiary care medical center. Infection Control and Hospital Epidemiology. 30: 848-53. PMID 19653819 DOI: 10.1086/599071  0.32
2009 Sow FB, Alvarez GR, Gross RP, Satoskar AR, Schlesinger LS, Zwilling BS, Lafuse WP. Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma. Journal of Leukocyte Biology. 86: 1247-58. PMID 19652026 DOI: 10.1189/jlb.1208719  0.36
2009 Chiu HC, Yang J, Soni S, Kulp SK, Gunn JS, Schlesinger LS, Chen CS. Pharmacological exploitation of an off-target antibacterial effect of the cyclooxygenase-2 inhibitor celecoxib against Francisella tularensis. Antimicrobial Agents and Chemotherapy. 53: 2998-3002. PMID 19398640 DOI: 10.1128/AAC.00048-09  0.44
2009 Premanandan C, Storozuk CA, Clay CD, Lairmore MD, Schlesinger LS, Phipps AJ. Complement protein C3 binding to Bacillus anthracis spores enhances phagocytosis by human macrophages. Microbial Pathogenesis. 46: 306-14. PMID 19328844 DOI: 10.1016/j.micpath.2009.03.004  0.36
2009 Torrelles JB, DesJardin LE, MacNeil J, Kaufman TM, Kutzbach B, Knaup R, McCarthy TR, Gurcha SS, Besra GS, Clegg S, Schlesinger LS. Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces the cell wall lipoarabinomannan and lipomannan content and increases the rate of bacterial-induced human macrophage cell death. Glycobiology. 19: 743-55. PMID 19318518 DOI: 10.1093/glycob/cwp042  0.36
2008 Clay CD, Soni S, Gunn JS, Schlesinger LS. Evasion of complement-mediated lysis and complement C3 deposition are regulated by Francisella tularensis lipopolysaccharide O antigen. Journal of Immunology (Baltimore, Md. : 1950). 181: 5568-78. PMID 18832715  0.44
2008 Torrelles JB, Knaup R, Kolareth A, Slepushkina T, Kaufman TM, Kang P, Hill PJ, Brennan PJ, Chatterjee D, Belisle JT, Musser JM, Schlesinger LS. Identification of Mycobacterium tuberculosis clinical isolates with altered phagocytosis by human macrophages due to a truncated lipoarabinomannan. The Journal of Biological Chemistry. 283: 31417-28. PMID 18784076 DOI: 10.1074/jbc.M806350200  0.36
2008 Azad AK, Torrelles JB, Schlesinger LS. Mutation in the DC-SIGN cytoplasmic triacidic cluster motif markedly attenuates receptor activity for phagocytosis and endocytosis of mannose-containing ligands by human myeloid cells. Journal of Leukocyte Biology. 84: 1594-603. PMID 18772280 DOI: 10.1189/jlb.0308192  0.32
2008 Butchar JP, Cremer TJ, Clay CD, Gavrilin MA, Wewers MD, Marsh CB, Schlesinger LS, Tridandapani S. Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion. Plos One. 3: e2924. PMID 18698339 DOI: 10.1371/journal.pone.0002924  0.44
2008 Van Zandt KE, Sow FB, Florence WC, Zwilling BS, Satoskar AR, Schlesinger LS, Lafuse WP. The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome. Journal of Leukocyte Biology. 84: 689-700. PMID 18586980 DOI: 10.1189/jlb.1107781  0.36
2008 Henning LN, Azad AK, Parsa KV, Crowther JE, Tridandapani S, Schlesinger LS. Pulmonary surfactant protein A regulates TLR expression and activity in human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 180: 7847-58. PMID 18523248  0.36
2008 Parsa KV, Butchar JP, Rajaram MV, Cremer TJ, Gunn JS, Schlesinger LS, Tridandapani S. Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNgamma response. Molecular Immunology. 45: 3428-37. PMID 18514317 DOI: 10.1016/j.molimm.2008.04.006  0.36
2008 Wang SH, Mangino JE, Stevenson K, Yakrus MA, Cooksey R, Butler WR, Healy M, Wise MG, Schlesinger LS, Pancholi P. Characterization of "Mycobacterium paraffinicum" associated with a pseudo-outbreak. Journal of Clinical Microbiology. 46: 1850-3. PMID 18367564 DOI: 10.1128/JCM.02079-07  0.32
2008 Ernst JD, Lewinsohn DM, Behar S, Blythe M, Schlesinger LS, Kornfeld H, Sette A. Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database. Tuberculosis (Edinburgh, Scotland). 88: 366-70. PMID 18068490 DOI: 10.1016/j.tube.2007.11.002  0.36
2007 Sow FB, Florence WC, Satoskar AR, Schlesinger LS, Zwilling BS, Lafuse WP. Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis. Journal of Leukocyte Biology. 82: 934-45. PMID 17609338 DOI: 10.1189/jlb.0407216  0.36
2007 Butchar JP, Rajaram MV, Ganesan LP, Parsa KV, Clay CD, Schlesinger LS, Tridandapani S. Francisella tularensis induces IL-23 production in human monocytes. Journal of Immunology (Baltimore, Md. : 1950). 178: 4445-54. PMID 17372002  0.36
2007 Mohapatra NP, Balagopal A, Soni S, Schlesinger LS, Gunn JS. AcpA is a Francisella acid phosphatase that affects intramacrophage survival and virulence. Infection and Immunity. 75: 390-6. PMID 17060465 DOI: 10.1128/IAI.01226-06  0.44
2006 Ferguson JS, Martin JL, Azad AK, McCarthy TR, Kang PB, Voelker DR, Crouch EC, Schlesinger LS. Surfactant protein D increases fusion of Mycobacterium tuberculosis-containing phagosomes with lysosomes in human macrophages. Infection and Immunity. 74: 7005-9. PMID 17030585 DOI: 10.1128/IAI.01402-06  0.36
2006 Balagopal A, MacFarlane AS, Mohapatra N, Soni S, Gunn JS, Schlesinger LS. Characterization of the receptor-ligand pathways important for entry and survival of Francisella tularensis in human macrophages. Infection and Immunity. 74: 5114-25. PMID 16926403 DOI: 10.1128/IAI.00795-06  0.44
2006 Torrelles JB, Azad AK, Schlesinger LS. Fine discrimination in the recognition of individual species of phosphatidyl-myo-inositol mannosides from Mycobacterium tuberculosis by C-type lectin pattern recognition receptors. Journal of Immunology (Baltimore, Md. : 1950). 177: 1805-16. PMID 16849491  0.32
2006 Parsa KV, Ganesan LP, Rajaram MV, Gavrilin MA, Balagopal A, Mohapatra NP, Wewers MD, Schlesinger LS, Gunn JS, Tridandapani S. Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP. Plos Pathogens. 2: e71. PMID 16848641 DOI: 10.1371/journal.ppat.0020071  0.36
2006 Hall-Stoodley L, Watts G, Crowther JE, Balagopal A, Torrelles JB, Robison-Cox J, Bargatze RF, Harmsen AG, Crouch EC, Schlesinger LS. Mycobacterium tuberculosis binding to human surfactant proteins A and D, fibronectin, and small airway epithelial cells under shear conditions. Infection and Immunity. 74: 3587-96. PMID 16714591 DOI: 10.1128/IAI.01644-05  0.36
2006 Crowther JE, Schlesinger LS. Endocytic pathway for surfactant protein A in human macrophages: binding, clathrin-mediated uptake, and trafficking through the endolysosomal pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L334-42. PMID 16169899 DOI: 10.1152/ajplung.00267.2005  0.36
2005 McCarthy TR, Torrelles JB, MacFarlane AS, Katawczik M, Kutzbach B, Desjardin LE, Clegg S, Goldberg JB, Schlesinger LS. Overexpression of Mycobacterium tuberculosis manB, a phosphomannomutase that increases phosphatidylinositol mannoside biosynthesis in Mycobacterium smegmatis and mycobacterial association with human macrophages. Molecular Microbiology. 58: 774-90. PMID 16238626 DOI: 10.1111/j.1365-2958.2005.04862.x  0.36
2005 Kang PB, Azad AK, Torrelles JB, Kaufman TM, Beharka A, Tibesar E, DesJardin LE, Schlesinger LS. The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis. The Journal of Experimental Medicine. 202: 987-99. PMID 16203868 DOI: 10.1084/jem.20051239  0.32
2005 Beharka AA, Crowther JE, McCormack FX, Denning GM, Lees J, Tibesar E, Schlesinger LS. Pulmonary surfactant protein A activates a phosphatidylinositol 3-kinase/calcium signal transduction pathway in human macrophages: participation in the up-regulation of mannose receptor activity. Journal of Immunology (Baltimore, Md. : 1950). 175: 2227-36. PMID 16081790  0.36
2004 Crowther JE, Kutala VK, Kuppusamy P, Ferguson JS, Beharka AA, Zweier JL, McCormack FX, Schlesinger LS. Pulmonary surfactant protein a inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity. Journal of Immunology (Baltimore, Md. : 1950). 172: 6866-74. PMID 15153505  0.36
2002 Mansour MK, Schlesinger LS, Levitz SM. Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors. Journal of Immunology (Baltimore, Md. : 1950). 168: 2872-9. PMID 11884457  0.36
2002 Ferguson JS, Voelker DR, Ufnar JA, Dawson AJ, Schlesinger LS. Surfactant protein D inhibition of human macrophage uptake of Mycobacterium tuberculosis is independent of bacterial agglutination. Journal of Immunology (Baltimore, Md. : 1950). 168: 1309-14. PMID 11801670  0.36
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