Year |
Citation |
Score |
2022 |
Moreira-Walsh B, Ragsdale A, Lam W, Upadhya R, Xu E, Lodge JK, Donlin MJ. Membrane Integrity Contributes to Resistance of Cryptococcus neoformans to the Cell Wall Inhibitor Caspofungin. Msphere. e0013422. PMID 35758672 DOI: 10.1128/msphere.00134-22 |
0.36 |
|
2020 |
Hole CR, Lam WC, Upadhya R, Lodge JK. Cryptococcus neoformans Chitin Synthase 3 Plays a Critical Role in Dampening Host Inflammatory Responses. Mbio. 11. PMID 32071275 DOI: 10.1128/Mbio.03373-19 |
0.385 |
|
2019 |
Maybruck BT, Lam WC, Specht CA, Ilagan MXG, Donlin MJ, Lodge JK. The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in Cryptococcus neoformans. Mbio. 10. PMID 31848271 DOI: 10.1128/Mbio.02264-19 |
0.353 |
|
2018 |
Upadhya R, Baker LG, Lam WC, Specht CA, Donlin MJ, Lodge JK. Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis. Mbio. 9. PMID 30459196 DOI: 10.1128/Mbio.02087-18 |
0.462 |
|
2017 |
Upadhya R, Lam WC, Maybruck B, Donlin MJ, Chang AL, Kayode S, Ormerod KL, Fraser JA, Doering TL, Lodge JK. A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome. Fungal Genetics and Biology : Fg & B. PMID 28870457 DOI: 10.1016/J.Fgb.2017.08.008 |
0.392 |
|
2016 |
Homer CM, Summers DK, Goranov AI, Clarke SC, Wiesner DL, Diedrich JK, Moresco JJ, Toffaletti D, Upadhya R, Caradonna I, Petnic S, Pessino V, Cuomo CA, Lodge JK, Perfect J, et al. Intracellular Action of a Secreted Peptide Required for Fungal Virulence. Cell Host & Microbe. PMID 27212659 DOI: 10.1016/J.Chom.2016.05.001 |
0.363 |
|
2016 |
Upadhya R, Lam WC, Maybruck B, Specht CA, Levitz SM, Lodge JK. Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans. Mbio. 7. PMID 27165801 DOI: 10.1128/Mbio.00547-16 |
0.396 |
|
2014 |
Donlin MJ, Upadhya R, Gerik KJ, Lam W, VanArendonk LG, Specht CA, Sharma NK, Lodge JK. Cross talk between the cell wall integrity and cyclic AMP/protein kinase A pathways in Cryptococcus neoformans. Mbio. 5. PMID 25118241 DOI: 10.1128/Mbio.01573-14 |
0.448 |
|
2014 |
Upadhya R, Donlin MJ, Lodge JK. Cryptococcus at work: gene expression during human infection. Mbio. 5: e01097. PMID 24757217 DOI: 10.1128/Mbio.01097-14 |
0.31 |
|
2014 |
Janbon G, Ormerod KL, Paulet D, Byrnes EJ, Yadav V, Chatterjee G, Mullapudi N, Hon CC, Billmyre RB, Brunel F, Bahn YS, Chen W, Chen Y, Chow EW, Coppée JY, ... ... Lodge JK, et al. Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. Plos Genetics. 10: e1004261. PMID 24743168 DOI: 10.1371/Journal.Pgen.1004261 |
0.364 |
|
2013 |
Upadhya R, Kim H, Jung KW, Park G, Lam W, Lodge JK, Bahn YS. Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway in Cryptococcus neoformans and contributes to fungal virulence. Molecular Microbiology. 90: 630-48. PMID 23998805 DOI: 10.1111/Mmi.12388 |
0.427 |
|
2013 |
Upadhya R, Campbell LT, Donlin MJ, Aurora R, Lodge JK. Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress. Plos One. 8: e55110. PMID 23383070 DOI: 10.1371/Journal.Pone.0055110 |
0.37 |
|
2013 |
Lam WC, Gerik KJ, Lodge JK. Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 signaling pathway in response to thermal stress. Eukaryotic Cell. 12: 118-31. PMID 23159519 DOI: 10.1128/Ec.05305-11 |
0.357 |
|
2013 |
Chabrier-Roselló Y, Gerik KJ, Koselny K, DiDone L, Lodge JK, Krysan DJ. Cryptococcus neoformans phosphoinositide-dependent kinase 1 (PDK1) ortholog is required for stress tolerance and survival in murine phagocytes. Eukaryotic Cell. 12: 12-22. PMID 23087368 DOI: 10.1128/Ec.00235-12 |
0.429 |
|
2012 |
Gilbert NM, Baker LG, Specht CA, Lodge JK. A glycosylphosphatidylinositol anchor is required for membrane localization but dispensable for cell wall association of chitin deacetylase 2 in Cryptococcus neoformans. Mbio. 3. PMID 22354955 DOI: 10.1128/Mbio.00007-12 |
0.667 |
|
2012 |
Baker LG, Lodge JK. Galactose-Inducible promoters in Cryptococcus neoformans var. grubii. Methods in Molecular Biology (Clifton, N.J.). 845: 211-26. PMID 22328377 DOI: 10.1007/978-1-61779-539-8_14 |
0.334 |
|
2012 |
Baker LG, Lodge JK. Multiple gene deletion in Cryptococcus neoformans using the Cre-lox system. Methods in Molecular Biology (Clifton, N.J.). 845: 85-98. PMID 22328369 DOI: 10.1007/978-1-61779-539-8_6 |
0.352 |
|
2011 |
Baker LG, Specht CA, Lodge JK. Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryotic Cell. 10: 1264-8. PMID 21784998 DOI: 10.1128/Ec.05138-11 |
0.435 |
|
2010 |
Brown SM, Upadhya R, Shoemaker JD, Lodge JK. Isocitrate dehydrogenase is important for nitrosative stress resistance in Cryptococcus neoformans, but oxidative stress resistance is not dependent on glucose-6-phosphate dehydrogenase. Eukaryotic Cell. 9: 971-80. PMID 20400467 DOI: 10.1128/Ec.00271-09 |
0.34 |
|
2010 |
Gilbert NM, Donlin MJ, Gerik KJ, Specht CA, Djordjevic JT, Wilson CF, Sorrell TC, Lodge JK. KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans. Molecular Microbiology. 76: 517-34. PMID 20384682 DOI: 10.1111/J.1365-2958.2010.07119.X |
0.667 |
|
2010 |
Patel RD, Lodge JK, Baker LG. Going green in Cryptococcus neoformans: the recycling of a selectable drug marker. Fungal Genetics and Biology : Fg & B. 47: 191-8. PMID 19944774 DOI: 10.1016/J.Fgb.2009.11.007 |
0.369 |
|
2009 |
Baker LG, Specht CA, Lodge JK. Chitinases are essential for sexual development but not vegetative growth in Cryptococcus neoformans. Eukaryotic Cell. 8: 1692-705. PMID 19734369 DOI: 10.1128/Ec.00227-09 |
0.43 |
|
2009 |
Geunes-Boyer S, Oliver TN, Janbon G, Lodge JK, Heitman J, Perfect JR, Wright JR. Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival. Infection and Immunity. 77: 2783-94. PMID 19451250 DOI: 10.1128/Iai.00088-09 |
0.37 |
|
2009 |
Ruff JA, Lodge JK, Baker LG. Three galactose inducible promoters for use in C. neoformans var. grubii. Fungal Genetics and Biology : Fg & B. 46: 9-16. PMID 18952189 DOI: 10.1016/J.Fgb.2008.10.003 |
0.363 |
|
2008 |
Gerik KJ, Bhimireddy SR, Ryerse JS, Specht CA, Lodge JK. PKC1 is essential for protection against both oxidative and nitrosative stresses, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans. Eukaryotic Cell. 7: 1685-98. PMID 18689526 DOI: 10.1128/Ec.00146-08 |
0.443 |
|
2007 |
Brown SM, Campbell LT, Lodge JK. Cryptococcus neoformans, a fungus under stress. Current Opinion in Microbiology. 10: 320-5. PMID 17707685 DOI: 10.1016/J.Mib.2007.05.014 |
0.335 |
|
2007 |
Baker LG, Specht CA, Donlin MJ, Lodge JK. Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans. Eukaryotic Cell. 6: 855-67. PMID 17400891 DOI: 10.1128/Ec.00399-06 |
0.465 |
|
2006 |
Goins CL, Gerik KJ, Lodge JK. Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: absence of Ku proteins increases homologous recombination, and co-transformation of independent DNA molecules allows rapid complementation of deletion phenotypes. Fungal Genetics and Biology : Fg & B. 43: 531-44. PMID 16714127 DOI: 10.1016/J.Fgb.2006.02.007 |
0.366 |
|
2006 |
Missall TA, Pusateri ME, Donlin MJ, Chambers KT, Corbett JA, Lodge JK. Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence. Eukaryotic Cell. 5: 518-29. PMID 16524907 DOI: 10.1128/Ec.5.3.518-529.2006 |
0.375 |
|
2005 |
Tang RJ, Breger J, Idnurm A, Gerik KJ, Lodge JK, Heitman J, Calderwood SB, Mylonakis E. Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach. Infection and Immunity. 73: 8219-25. PMID 16299318 DOI: 10.1128/Iai.73.12.8219-8225.2005 |
0.42 |
|
2005 |
Banks IR, Specht CA, Donlin MJ, Gerik KJ, Levitz SM, Lodge JK. A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans. Eukaryotic Cell. 4: 1902-12. PMID 16278457 DOI: 10.1128/Ec.4.11.1902-1912.2005 |
0.469 |
|
2005 |
Gerik KJ, Donlin MJ, Soto CE, Banks AM, Banks IR, Maligie MA, Selitrennikoff CP, Lodge JK. Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans. Molecular Microbiology. 58: 393-408. PMID 16194228 DOI: 10.1111/J.1365-2958.2005.04843.X |
0.43 |
|
2005 |
Missall TA, Cherry-Harris JF, Lodge JK. Two glutathione peroxidases in the fungal pathogen Cryptococcus neoformans are expressed in the presence of specific substrates. Microbiology (Reading, England). 151: 2573-81. PMID 16079336 DOI: 10.1099/Mic.0.28132-0 |
0.35 |
|
2005 |
Missall TA, Lodge JK. Function of the thioredoxin proteins in Cryptococcus neoformans during stress or virulence and regulation by putative transcriptional modulators. Molecular Microbiology. 57: 847-58. PMID 16045626 DOI: 10.1111/J.1365-2958.2005.04735.X |
0.401 |
|
2005 |
Missall TA, Lodge JK. Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans. Eukaryotic Cell. 4: 487-9. PMID 15701811 DOI: 10.1128/Ec.4.2.487-489.2005 |
0.399 |
|
2005 |
Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson IJ, Fraser JA, Allen JE, Bosdet IE, Brent MR, Chiu R, Doering TL, ... ... Lodge JK, et al. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science (New York, N.Y.). 307: 1321-4. PMID 15653466 DOI: 10.1126/Science.1103773 |
0.367 |
|
2005 |
Missall TA, Moran JM, Corbett JA, Lodge JK. Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1. Eukaryotic Cell. 4: 202-8. PMID 15643075 DOI: 10.1128/Ec.4.1.202-208.2005 |
0.431 |
|
2004 |
Missall TA, Lodge JK, McEwen JE. Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts. Eukaryotic Cell. 3: 835-46. PMID 15302816 DOI: 10.1128/Ec.3.4.835-846.2004 |
0.317 |
|
2004 |
Missall TA, Pusateri ME, Lodge JK. Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans. Molecular Microbiology. 51: 1447-58. PMID 14982637 DOI: 10.1111/J.1365-2958.2004.03921.X |
0.437 |
|
2003 |
Nelson RT, Pryor BA, Lodge JK. Sequence length required for homologous recombination in Cryptococcus neoformans. Fungal Genetics and Biology : Fg & B. 38: 1-9. PMID 12553931 DOI: 10.1016/S1087-1845(02)00510-8 |
0.322 |
|
2001 |
Tumer NE, Kaniewski W, Haley L, Gehrke L, Lodge JK, Sanders P. The second amino acid of alfalfa mosaic virus coat protein is critical for coat protein-mediated protection. Proceedings of the National Academy of Sciences of the United States of America. 88: 2331-5. PMID 11607167 DOI: 10.1073/Pnas.88.6.2331 |
0.309 |
|
2000 |
Heitman J, Casadevall A, Lodge JK, Perfect JR. The Cryptococcus neoformans genome sequencing project. Mycopathologia. 148: 1-7. PMID 11086479 DOI: 10.1023/A:1007136602930 |
0.332 |
|
1998 |
Lodge JK, Jackson-Machelski E, Higgins M, McWherter CA, Sikorski JA, Devadas B, Gordon JI. Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent. The Journal of Biological Chemistry. 273: 12482-91. PMID 9575206 DOI: 10.1074/Jbc.273.20.12482 |
0.383 |
|
1997 |
Lodge JK, Jackson-Machelski E, Devadas B, Zupec ME, Getman DP, Kishore N, Freeman SK, McWherter CA, Sikorski JA, Gordon JI. N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase. Microbiology (Reading, England). 357-66. PMID 9043113 DOI: 10.1099/00221287-143-2-357 |
0.368 |
|
1995 |
Lodge JK, Jackson-Machelski E, Toffaletti DL, Perfect JR, Gordon JI. Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans. Proceedings of the National Academy of Sciences of the United States of America. 91: 12008-12. PMID 7991574 DOI: 10.1073/Pnas.91.25.12008 |
0.388 |
|
1995 |
Maresca B, Bennett J, Fonzi W, Hitchcock CA, Lodge JK, Williamson PR. Molecular approaches to identify novel targets for future development of antifungal agents. Journal of Medical and Veterinary Mycology : Bi-Monthly Publication of the International Society For Human and Animal Mycology. 287-98. PMID 7722794 DOI: 10.1080/02681219480000911 |
0.368 |
|
1989 |
Lodge JK, Kazic T, Berg DE. Formation of supercoiling domains in plasmid pBR322. Journal of Bacteriology. 171: 2181-7. PMID 2649489 DOI: 10.1128/Jb.171.4.2181-2187.1989 |
0.318 |
|
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