Manoj T. Duraisingh - Publications

Harvard University, Cambridge, MA, United States 
Parasitology Biology, Genetics, Microbiology Biology

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gnangnon B, Duraisingh MT, Buckee CO. Deconstructing the parasite multiplication rate of Plasmodium falciparum. Trends in Parasitology. PMID 34119440 DOI: 10.1016/  0.52
2021 Clark MA, Kanjee U, Rangel GW, Chery L, Mascarenhas A, Gomes E, Rathod PK, Brugnara C, Ferreira MU, Duraisingh MT. Plasmodium vivax infection compromises reticulocyte stability. Nature Communications. 12: 1629. PMID 33712609 DOI: 10.1038/s41467-021-21886-x  0.32
2021 Proto WR, Siegel SV, Dankwa S, Liu W, Kemp A, Marsden S, Zenonos ZA, Unwin S, Sharp PM, Wright GJ, Hahn BH, Duraisingh MT, Rayner JC. Author Correction: Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand. Nature Communications. 12: 1188. PMID 33594063 DOI: 10.1038/s41467-021-21491-y  0.32
2020 Cai F, DeSimone TM, Hansen E, Jennings CV, Bei AK, Ahouidi AD, Mboup S, Duraisingh MT, Buckee CO. Accounting for red blood cell accessibility reveals distinct invasion strategies in Plasmodium falciparum strains. Plos Computational Biology. 16: e1007702. PMID 32315315 DOI: 10.1371/Journal.Pcbi.1007702  0.68
2020 Cai FY, DeSimone TM, Hansen E, Jennings CV, Bei AK, Ahouidi AD, Mboup S, Duraisingh MT, Buckee CO. Additional modeling details. Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.1007702.S011  0.68
2020 Cai FY, DeSimone TM, Hansen E, Jennings CV, Bei AK, Ahouidi AD, Mboup S, Duraisingh MT, Buckee CO. Distribution of multiplicity used to estimate invasion profile of the Dd2Nm strain. Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.1007702.S005  0.68
2020 Cai FY, DeSimone TM, Hansen E, Jennings CV, Bei AK, Ahouidi AD, Mboup S, Duraisingh MT, Buckee CO. Invasion strategies of field strains. Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.1007702.S004  0.68
2020 Cai FY, DeSimone TM, Hansen E, Jennings CV, Bei AK, Ahouidi AD, Mboup S, Duraisingh MT, Buckee CO. Maximum likelihood estimate of the fraction susceptible fMLE (y-axis) and λMLE (x-axis) for six lab strains, stratified by age of red blood cell fraction. Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.1007702.S003  0.68
2020 Cai FY, DeSimone TM, Hansen E, Jennings CV, Bei AK, Ahouidi AD, Mboup S, Duraisingh MT, Buckee CO. Relative post-invasion parasitemia versus strains. Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.1007702.S002  0.68
2020 Cai FY, DeSimone TM, Hansen E, Jennings CV, Bei AK, Ahouidi AD, Mboup S, Duraisingh MT, Buckee CO. Comparison of Poisson and zero-inflated Poisson model fits. Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.1007702.S001  0.68
2019 Proto WR, Siegel SV, Dankwa S, Liu W, Kemp A, Marsden S, Zenonos ZA, Unwin S, Sharp PM, Wright GJ, Hahn BH, Duraisingh MT, Rayner JC. Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand. Nature Communications. 10: 4512. PMID 31586047 DOI: 10.1038/S41467-019-12294-3  0.32
2018 Wong W, Huang R, Menant S, Hong C, Sandow JJ, Birkinshaw RW, Healer J, Hodder AN, Kanjee U, Tonkin CJ, Heckmann D, Soroka V, Søgaard TMM, Jørgensen T, Duraisingh MT, et al. Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex. Nature. PMID 30542156 DOI: 10.1038/s41586-018-0779-6  0.36
2018 Egan ES, Weekes MP, Kanjee U, Manzo J, Srinivasan A, Lomas-Francis C, Westhoff C, Takahashi J, Tanaka M, Watanabe S, Brugnara C, Gygi SP, Tani Y, Duraisingh MT. Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite . Communications Biology. 1: 45. PMID 30271928 DOI: 10.1038/s42003-018-0046-2  0.32
2018 Archer NM, Petersen N, Clark MA, Buckee CO, Childs LM, Duraisingh MT. Resistance to in sickle cell trait erythrocytes is driven by oxygen-dependent growth inhibition. Proceedings of the National Academy of Sciences of the United States of America. PMID 29946035 DOI: 10.1073/Pnas.1804388115  0.52
2018 Wong W, Huang R, Menant S, Hong C, Sandow JJ, Birkinshaw RW, Healer J, Hodder AN, Kanjee U, Tonkin CJ, Heckmann D, Soroka V, Søgaard TMM, Jørgensen T, Duraisingh MT, et al. Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex. Nature. 565: 118-121. DOI: 10.2210/Pdb6Mpv/Pdb  0.36
2017 Wirth DF, Winzeler EA, Fenton B, Adams JH, Ariey F, Barillas-Mury CV, Baum J, Bhatia SN, Billker O, Bopp SE, Catteruccia F, Cowman AF, Chitnis CE, Crabb BS, Deitsch KW, ... ... Duraisingh MT, et al. malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication Plos Medicine. 14. PMID 29190277 DOI: 10.1371/Journal.Pmed.1002451  0.36
2017 Cowman AF, Tonkin CJ, Tham WH, Duraisingh MT. The Molecular Basis of Erythrocyte Invasion by Malaria Parasites. Cell Host & Microbe. 22: 232-245. PMID 28799908 DOI: 10.1016/J.Chom.2017.07.003  0.36
2017 Dankwa S, Chaand M, Kanjee U, Jiang RHY, Nobre LV, Goldberg JM, Bei AK, Moechtar MA, Grüring C, Ahouidi AD, Ndiaye D, Dieye TN, Mboup S, Weekes MP, Duraisingh MT. Genetic evidence for erythrocyte receptor glycophorin B expression levels defining a dominant Plasmodium falciparum invasion pathway into human erythrocytes. Infection and Immunity. PMID 28760933 DOI: 10.1128/Iai.00074-17  0.68
2017 Kumar S, Kumar M, Ekka R, Dvorin JD, Paul AS, Madugundu AK, Gilberger T, Gowda H, Duraisingh MT, Keshava Prasad TS, Sharma P. PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum. Nature Communications. 8: 63. PMID 28680058 DOI: 10.1038/S41467-017-00053-1  0.4
2017 Bei AK, Ahouidi AD, Dvorin JD, Miura K, Diouf A, Ndiaye D, Premji Z, Diakite M, Mboup S, Long CA, Duraisingh MT. Functional analysis reveals geographical variation in inhibitory immune responses against a polymorphic malaria antigen. The Journal of Infectious Diseases. PMID 28605544 DOI: 10.1093/Infdis/Jix280  0.68
2017 Ganter M, Goldberg JM, Dvorin JD, Paulo JA, King JG, Tripathi AK, Paul AS, Yang J, Coppens I, Jiang RH, Elsworth B, Baker DA, Dinglasan RR, Gygi SP, Duraisingh MT. Erratum: Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony. Nature Microbiology. 2: 17038. PMID 28263306 DOI: 10.1038/nmicrobiol.2017.38  0.4
2017 Ganter M, Goldberg JM, Dvorin JD, Paulo JA, King JG, Tripathi AK, Paul AS, Yang J, Coppens I, Jiang RH, Elsworth B, Baker DA, Dinglasan RR, Gygi SP, Duraisingh MT. Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony. Nature Microbiology. 2: 17017. PMID 28211852 DOI: 10.1038/Nmicrobiol.2017.17  0.4
2016 Hostetler JB, Lo E, Kanjee U, Amaratunga C, Suon S, Sreng S, Mao S, Yewhalaw D, Mascarenhas A, Kwiatkowski DP, Ferreira MU, Rathod PK, Yan G, Fairhurst RM, Duraisingh MT, et al. Independent Origin and Global Distribution of Distinct Plasmodium vivax Duffy Binding Protein Gene Duplications. Plos Neglected Tropical Diseases. 10: e0005091. PMID 27798646 DOI: 10.1371/Journal.Pntd.0005091  0.32
2016 Shaw-Saliba K, Thomson-Luque R, Obaldía N, Nuñez M, Dutary S, Lim C, Barnes S, Kocken CH, Duraisingh MT, Adams JH, Pasini EM. Insights into an Optimization of Plasmodium vivax Sal-1 In Vitro Culture: The Aotus Primate Model. Plos Neglected Tropical Diseases. 10: e0004870. PMID 27463518 DOI: 10.1371/Journal.Pntd.0004870  0.48
2016 Shaw-Saliba K, Clarke D, Santos JM, Menezes MJ, Lim C, Mascarenhas A, Chery L, Gomes E, March S, Bhatia SN, Rathod PK, Ferreira MU, Catteruccia F, Duraisingh MT. Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates. International Journal For Parasitology. PMID 27456552 DOI: 10.1016/J.Ijpara.2016.06.003  0.48
2016 Paul AS, Moreira CK, Elsworth B, Allred DR, Duraisingh MT. Extensive shared chemosensitivity between malaria and babesiosis blood-stage parasites. Antimicrobial Agents and Chemotherapy. PMID 27246780 DOI: 10.1128/Aac.00928-16  0.48
2016 Lim C, Pereira L, Shardul P, Mascarenhas A, Maki J, Rixon J, Shaw-Saliba K, White J, Silveira M, Gomes E, Chery L, Rathod PK, Duraisingh MT. Improved light microscopy counting method for accurately counting Plasmodium parasitemia and reticulocytemia. American Journal of Hematology. PMID 27074559 DOI: 10.1002/Ajh.24383  0.48
2016 Dankwa S, Lim C, Bei AK, Jiang RH, Abshire JR, Patel SD, Goldberg JM, Moreno Y, Kono M, Niles JC, Duraisingh MT. Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite. Nature Communications. 7: 11187. PMID 27041489 DOI: 10.1038/Ncomms11187  0.48
2016 Obaldía Iii N, Dow GS, Gerena L, Kyle D, Otero W, Mantel PY, Baro N, Daniels R, Mukherjee A, Childs LM, Buckee C, Duraisingh MT, Volkman SK, Wirth DF, Marti M. Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model. Scientific Reports. 6: 21216. PMID 26880111 DOI: 10.1038/Srep21216  0.48
2015 Ahouidi AD, Amambua-Ngwa A, Awandare GA, Bei AK, Conway DJ, Diakite M, Duraisingh MT, Rayner JC, Zenonos ZA. Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN). Trends in Parasitology. PMID 26725306 DOI: 10.1016/J.Pt.2015.11.009  0.48
2015 Tubman VN, Mejia P, Shmukler BE, Bei AK, Alper SL, Mitchell JR, Brugnara C, Duraisingh MT. The clinically tested Gardos channel inhibitor, senicapoc, exhibits antimalarial activity. Antimicrobial Agents and Chemotherapy. PMID 26459896 DOI: 10.1128/Aac.01668-15  0.48
2015 Bei AK, Duraisingh MT. Measuring Plasmodium falciparum Erythrocyte Invasion Phenotypes Using Flow Cytometry. Methods in Molecular Biology (Clifton, N.J.). 1325: 167-86. PMID 26450388 DOI: 10.1007/978-1-4939-2815-6_14  0.68
2015 Assefa S, Lim C, Preston MD, Duffy CW, Nair MB, Adroub SA, Kadir KA, Goldberg JM, Neafsey DE, Divis P, Clark TG, Duraisingh MT, Conway DJ, Pain A, Singh B. Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438871 DOI: 10.1073/Pnas.1509534112  0.48
2015 Wassmer SC, Taylor TE, Rathod PK, Mishra SK, Mohanty S, Arevalo-Herrera M, Duraisingh MT, Smith JD. Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach. The American Journal of Tropical Medicine and Hygiene. 93: 42-56. PMID 26259939 DOI: 10.4269/Ajtmh.14-0841  0.48
2015 Paul AS, Saha S, Engelberg K, Jiang RH, Coleman BI, Kosber AL, Chen CT, Ganter M, Espy N, Gilberger TW, Gubbels MJ, Duraisingh MT. Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans. Cell Host & Microbe. PMID 26118996 DOI: 10.1016/J.Chom.2015.06.003  0.48
2015 Egan ES, Jiang RH, Moechtar MA, Barteneva NS, Weekes MP, Nobre LV, Gygi SP, Paulo JA, Frantzreb C, Tani Y, Takahashi J, Watanabe S, Goldberg J, Paul AS, Brugnara C, ... ... Duraisingh MT, et al. Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion. Science (New York, N.Y.). 348: 711-4. PMID 25954012 DOI: 10.1126/Science.Aaa3526  0.48
2015 Merrick CJ, Jiang RH, Skillman KM, Samarakoon U, Moore RM, Dzikowski R, Ferdig MT, Duraisingh MT. Functional analysis of sirtuin genes in multiple Plasmodium falciparum strains. Plos One. 10: e0118865. PMID 25780929 DOI: 10.1371/Journal.Pone.0118865  0.48
2015 Paul AS, Egan ES, Duraisingh MT. Host-parasite interactions that guide red blood cell invasion by malaria parasites. Current Opinion in Hematology. 22: 220-6. PMID 25767956 DOI: 10.1097/Moh.0000000000000135  0.48
2015 Choi JY, Duraisingh MT, Marti M, Ben Mamoun C, Voelker DR. From Protease to Decarboxylase: THE MOLECULAR METAMORPHOSIS OF PHOSPHATIDYLSERINE DECARBOXYLASE. The Journal of Biological Chemistry. 290: 10972-80. PMID 25724650 DOI: 10.1074/Jbc.M115.642413  0.48
2015 Mejia P, Treviño-Villarreal JH, Hine C, Harputlugil E, Lang S, Calay E, Rogers R, Wirth D, Duraisingh MT, Mitchell JR. Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression. Nature Communications. 6: 6050. PMID 25636003 DOI: 10.1038/Ncomms7050  0.48
2015 Kumar AA, Lim C, Moreno Y, Mace CR, Syed A, Van Tyne D, Wirth DF, Duraisingh MT, Whitesides GM. Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers. American Journal of Hematology. 90: 31-6. PMID 25263455 DOI: 10.1002/Ajh.23860  0.48
2014 Coleman BI, Skillman KM, Jiang RH, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BF, Marti M, Llinás M, Buckee CO, Duraisingh MT. A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion. Cell Host & Microbe. 16: 177-86. PMID 25121747 DOI: 10.1016/J.Chom.2014.06.014  0.48
2014 Niang M, Bei AK, Madnani KG, Pelly S, Dankwa S, Kanjee U, Gunalan K, Amaladoss A, Yeo KP, Bob NS, Malleret B, Duraisingh MT, Preiser PR. STEVOR is a Plasmodium falciparum erythrocyte binding protein that mediates merozoite invasion and rosetting. Cell Host & Microbe. 16: 81-93. PMID 25011110 DOI: 10.1016/J.Chom.2014.06.004  0.48
2014 Joice R, Nilsson SK, Montgomery J, Dankwa S, Egan E, Morahan B, Seydel KB, Bertuccini L, Alano P, Williamson KC, Duraisingh MT, Taylor TE, Milner DA, Marti M. Plasmodium falciparum transmission stages accumulate in the human bone marrow. Science Translational Medicine. 6: 244re5. PMID 25009232 DOI: 10.1126/Scitranslmed.3008882  0.48
2014 Horn D, Duraisingh MT. Antiparasitic chemotherapy: from genomes to mechanisms. Annual Review of Pharmacology and Toxicology. 54: 71-94. PMID 24050701 DOI: 10.1146/Annurev-Pharmtox-011613-135915  0.48
2013 Patel SD, Ahouidi AD, Bei AK, Dieye TN, Mboup S, Harrison SC, Duraisingh MT. Plasmodium falciparum merozoite surface antigen, PfRH5, elicits detectable levels of invasion-inhibiting antibodies in humans. The Journal of Infectious Diseases. 208: 1679-87. PMID 23904294 DOI: 10.1093/Infdis/Jit385  0.48
2013 Badiane AS, Bei AK, Ahouidi AD, Patel SD, Salinas N, Ndiaye D, Sarr O, Ndir O, Tolia NH, Mboup S, Duraisingh MT. Inhibitory humoral responses to the Plasmodium falciparum vaccine candidate EBA-175 are independent of the erythrocyte invasion pathway. Clinical and Vaccine Immunology : Cvi. 20: 1238-45. PMID 23761656 DOI: 10.1128/Cvi.00135-13  0.48
2013 Engelberg K, Paul AS, Prinz B, Kono M, Ching W, Heincke D, Dobner T, Spielmann T, Duraisingh MT, Gilberger TW. Specific phosphorylation of the PfRh2b invasion ligand of Plasmodium falciparum. The Biochemical Journal. 452: 457-66. PMID 23544851 DOI: 10.1042/Bj20121694  0.48
2013 Lim C, Hansen E, DeSimone TM, Moreno Y, Junker K, Bei A, Brugnara C, Buckee CO, Duraisingh MT. Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans. Nature Communications. 4: 1638. PMID 23535659 DOI: 10.1038/Ncomms2612  0.48
2013 Duraisingh MT, Dvorin JD, Preiser PR. Invasion Ligand Diversity and Pathogenesis in Blood-Stage Malaria Evolution of Virulence in Eukaryotic Microbes. 362-383. DOI: 10.1002/9781118308165.ch19  0.48
2012 Coleman BI, Ribacke U, Manary M, Bei AK, Winzeler EA, Wirth DF, Duraisingh MT. Nuclear repositioning precedes promoter accessibility and is linked to the switching frequency of a Plasmodium falciparum invasion gene. Cell Host & Microbe. 12: 739-50. PMID 23245319 DOI: 10.1016/J.Chom.2012.11.004  0.48
2012 Badiane AS, Sarr O, Deme AB, Ahouidi AD, Gueye PE, Ndiaye M, Seck MC, Diallo M, Bei AK, Duraisingh MT, Wirth D, Ndiaye D, Ndir O, Mboup S. Distribution of erythrocyte binding antigen 175 (EBA-175) alleles and ABO blood groups in a hypoendemic area in Senegal. Journal of Infection in Developing Countries. 6: 727-33. PMID 23103895 DOI: 10.3855/Jidc.2587  0.48
2012 Duraisingh MT, Lodish HF. Sickle cell microRNAs inhibit the malaria parasite. Cell Host & Microbe. 12: 127-8. PMID 22901533 DOI: 10.1016/J.Chom.2012.08.001  0.48
2012 Bei AK, Duraisingh MT. Functional analysis of erythrocyte determinants of Plasmodium infection. International Journal For Parasitology. 42: 575-82. PMID 22726752 DOI: 10.1016/J.Ijpara.2012.03.006  0.68
2012 Merrick CJ, Huttenhower C, Buckee C, Amambua-Ngwa A, Gomez-Escobar N, Walther M, Conway DJ, Duraisingh MT. Epigenetic dysregulation of virulence gene expression in severe Plasmodium falciparum malaria. The Journal of Infectious Diseases. 205: 1593-600. PMID 22448008 DOI: 10.1093/Infdis/Jis239  0.48
2012 Narayanasamy K, Chery L, Basu A, Duraisingh MT, Escalante A, Fowble J, Guler JL, Herricks T, Kumar A, Majumder P, Maki J, Mascarenhas A, Rodrigues J, Roy B, Sen S, et al. Malaria evolution in South Asia: knowledge for control and elimination. Acta Tropica. 121: 256-66. PMID 22266213 DOI: 10.1016/J.Actatropica.2012.01.008  0.48
2012 Farrell A, Thirugnanam S, Lorestani A, Dvorin JD, Eidell KP, Ferguson DJ, Anderson-White BR, Duraisingh MT, Marth GT, Gubbels MJ. A DOC2 protein identified by mutational profiling is essential for apicomplexan parasite exocytosis. Science (New York, N.Y.). 335: 218-21. PMID 22246776 DOI: 10.1126/Science.1210829  0.48
2012 Doumbia SO, Ndiaye D, Koita OA, Diakité M, Nwakanma D, Coulibaly M, Traoré SF, Keating J, Milner DA, Ndiaye JL, Sene PD, Ahouidi A, Dieye TN, Gaye O, Okebe J, ... ... Duraisingh M, et al. Improving malaria control in West Africa: interruption of transmission as a paradigm shift. Acta Tropica. 121: 175-83. PMID 22142790 DOI: 10.1016/J.Actatropica.2011.11.009  0.48
2012 Ceesay SJ, Bojang KA, Nwakanma D, Conway DJ, Koita OA, Doumbia SO, Ndiaye D, Coulibaly TF, Diakité M, Traoré SF, Coulibaly M, Ndiaye JL, Sarr O, Gaye O, Konaté L, ... ... Duraisingh M, et al. Sahel, savana, riverine and urban malaria in West Africa: Similar control policies with different outcomes. Acta Tropica. 121: 166-74. PMID 22119584 DOI: 10.1016/J.Actatropica.2011.11.005  0.48
2011 Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, ... Duraisingh MT, et al. Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors. Chemistry & Biology. 18: 1602-10. PMID 22195562 DOI: 10.1016/J.Chembiol.2011.09.016  0.48
2011 Crosnier C, Bustamante LY, Bartholdson SJ, Bei AK, Theron M, Uchikawa M, Mboup S, Ndir O, Kwiatkowski DP, Duraisingh MT, Rayner JC, Wright GJ. Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum. Nature. 480: 534-7. PMID 22080952 DOI: 10.1038/nature10606  0.48
2011 Broadbent KM, Park D, Wolf AR, Van Tyne D, Sims JS, Ribacke U, Volkman S, Duraisingh M, Wirth D, Sabeti PC, Rinn JL. A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs. Genome Biology. 12: R56. PMID 21689454 DOI: 10.1186/Gb-2011-12-6-R56  0.48
2011 Barker RH, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, ... ... Duraisingh M, et al. Aminoindoles, a novel scaffold with potent activity against Plasmodium falciparum. Antimicrobial Agents and Chemotherapy. 55: 2612-22. PMID 21422215 DOI: 10.1128/Aac.01714-10  0.48
2011 Comeaux CA, Coleman BI, Bei AK, Whitehurst N, Duraisingh MT. Functional analysis of epigenetic regulation of tandem RhopH1/clag genes reveals a role in Plasmodium falciparum growth. Molecular Microbiology. 80: 378-90. PMID 21320181 DOI: 10.1111/J.1365-2958.2011.07572.X  1
2010 Bei AK, Brugnara C, Duraisingh MT. In vitro genetic analysis of an erythrocyte determinant of malaria infection. The Journal of Infectious Diseases. 202: 1722-7. PMID 20958212 DOI: 10.1086/657157  0.68
2010 Booker ML, Bastos CM, Kramer ML, Barker RH, Skerlj R, Sidhu AB, Deng X, Celatka C, Cortese JF, Guerrero Bravo JE, Crespo Llado KN, Serrano AE, Angulo-Barturen I, Jiménez-Díaz MB, Viera S, ... ... Duraisingh M, et al. Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model. The Journal of Biological Chemistry. 285: 33054-64. PMID 20702404 DOI: 10.1074/Jbc.M110.162081  0.48
2010 Dvorin JD, Bei AK, Coleman BI, Duraisingh MT. Functional diversification between two related Plasmodium falciparum merozoite invasion ligands is determined by changes in the cytoplasmic domain. Molecular Microbiology. 75: 990-1006. PMID 20487292 DOI: 10.1111/J.1365-2958.2009.07040.X  0.48
2010 Dvorin JD, Martyn DC, Patel SD, Grimley JS, Collins CR, Hopp CS, Bright AT, Westenberger S, Winzeler E, Blackman MJ, Baker DA, Wandless TJ, Duraisingh MT. A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes. Science (New York, N.Y.). 328: 910-2. PMID 20466936 DOI: 10.1126/Science.1188191  0.48
2010 Bei AK, Desimone TM, Badiane AS, Ahouidi AD, Dieye T, Ndiaye D, Sarr O, Ndir O, Mboup S, Duraisingh MT. A flow cytometry-based assay for measuring invasion of red blood cells by Plasmodium falciparum. American Journal of Hematology. 85: 234-7. PMID 20196166 DOI: 10.1002/Ajh.21642  0.68
2010 Artavanis-Tsakonas K, Weihofen WA, Antos JM, Coleman BI, Comeaux CA, Duraisingh MT, Gaudet R, Ploegh HL. Characterization and structural studies of the Plasmodium falciparum ubiquitin and Nedd8 hydrolase UCHL3. The Journal of Biological Chemistry. 285: 6857-66. PMID 20042598 DOI: 10.1074/Jbc.M109.072405  0.48
2010 Ahouidi AD, Bei AK, Neafsey DE, Sarr O, Volkman S, Milner D, Cox-Singh J, Ferreira MU, Ndir O, Premji Z, Mboup S, Duraisingh MT. Population genetic analysis of large sequence polymorphisms in Plasmodium falciparum blood-stage antigens. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 10: 200-6. PMID 19931645 DOI: 10.1016/J.Meegid.2009.11.008  0.48
2010 Bushkin GG, Ratner DM, Cui J, Banerjee S, Duraisingh MT, Jennings CV, Dvorin JD, Gubbels MJ, Robertson SD, Steffen M, O'Keefe BR, Robbins PW, Samuelson J. Suggestive evidence for Darwinian selection against asparagine-linked glycans of Plasmodium falciparum and Toxoplasma gondii Eukaryotic Cell. 9: 228-241. PMID 19783771 DOI: 10.1128/Ec.00197-09  0.48
2009 Tonkin CJ, Carret CK, Duraisingh MT, Voss TS, Ralph SA, Hommel M, Duffy MF, Silva LM, Scherf A, Ivens A, Speed TP, Beeson JG, Cowman AF. Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum. Plos Biology. 7: e84. PMID 19402747 DOI: 10.1371/Journal.Pbio.1000084  0.48
2009 DeSimone TM, Jennings CV, Bei AK, Comeaux C, Coleman BI, Refour P, Triglia T, Stubbs J, Cowman AF, Duraisingh MT. Cooperativity between Plasmodium falciparum adhesive proteins for invasion into erythrocytes. Molecular Microbiology. 72: 578-89. PMID 19400777 DOI: 10.1111/J.1365-2958.2009.06667.X  0.68
2009 Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J. Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum. Journal of Medicinal Chemistry. 52: 2185-7. PMID 19317450 DOI: 10.1021/Jm801654Y  0.48
2009 Lantos PM, Ahouidi AD, Bei AK, Jennings CV, Sarr O, Ndir O, Wirth DF, Mboup S, Duraisingh MT. Erythrocyte invasion profiles are associated with a common invasion ligand polymorphism in Senegalese isolates of Plasmodium falciparum. Parasitology. 136: 1-9. PMID 19126266 DOI: 10.1017/S0031182008005167  0.48
2009 Dong CK, Patel V, Yang JC, Dvorin JD, Duraisingh MT, Clardy J, Wirth DF. Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 972-5. PMID 19097788 DOI: 10.1016/J.Bmcl.2008.11.071  0.48
2009 DeSimone TM, Bei AK, Jennings CV, Duraisingh MT. Genetic analysis of the cytoplasmic domain of the PfRh2b merozoite invasion protein of Plasmodium falciparum. International Journal For Parasitology. 39: 399-405. PMID 18831976 DOI: 10.1016/J.Ijpara.2008.08.008  0.68
2008 Patel V, Booker M, Kramer M, Ross L, Celatka CA, Kennedy LM, Dvorin JD, Duraisingh MT, Sliz P, Wirth DF, Clardy J. Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. The Journal of Biological Chemistry. 283: 35078-85. PMID 18842591 DOI: 10.1074/Jbc.M804990200  0.48
2008 Coleman BI, Duraisingh MT. Transcriptional control and gene silencing in Plasmodium falciparum. Cellular Microbiology. 10: 1935-46. PMID 18637022 DOI: 10.1111/J.1462-5822.2008.01203.X  0.68
2008 Duraisingh MT, DeSimone T, Jennings C, Refour P, Wu C. Erythrocyte invasion by Plasmodium falciparum: multiple ligand-receptor interactions and phenotypic switching. Sub-Cellular Biochemistry. 47: 46-57. PMID 18512340 DOI: 10.1007/978-0-387-78267-6_3  0.48
2008 Zhou Y, Ramachandran V, Kumar KA, Westenberger S, Refour P, Zhou B, Li F, Young JA, Chen K, Plouffe D, Henson K, Nussenzweig V, Carlton J, Vinetz JM, Duraisingh MT, et al. Evidence-based annotation of the malaria parasite's genome using comparative expression profiling. Plos One. 3: e1570. PMID 18270564 DOI: 10.1371/Journal.Pone.0001570  0.48
2008 Militello KT, Refour P, Comeaux CA, Duraisingh MT. Antisense RNA and RNAi in protozoan parasites: working hard or hardly working? Molecular and Biochemical Parasitology. 157: 117-26. PMID 18053590 DOI: 10.1016/J.Molbiopara.2007.10.004  0.48
2007 Comeaux CA, Duraisingh MT. Unravelling a histone code for malaria virulence. Molecular Microbiology. 66: 1291-5. PMID 18028316 DOI: 10.1111/J.1365-2958.2007.06038.X  1
2007 Deitsch K, Duraisingh M, Dzikowski R, Gunasekera A, Khan S, Le Roch K, Llinás M, Mair G, McGovern V, Roos D, Shock J, Sims J, Wiegand R, Winzeler E. Mechanisms of gene regulation in Plasmodium. The American Journal of Tropical Medicine and Hygiene. 77: 201-8. PMID 17690387  0.48
2007 Jennings CV, Ahouidi AD, Zilversmit M, Bei AK, Rayner J, Sarr O, Ndir O, Wirth DF, Mboup S, Duraisingh MT. Molecular analysis of erythrocyte invasion in Plasmodium falciparum isolates from Senegal Infection and Immunity. 75: 3531-3538. PMID 17470537 DOI: 10.1128/Iai.00122-07  0.48
2007 Bei AK, Membi CD, Rayner JC, Mubi M, Ngasala B, Sultan AA, Premji Z, Duraisingh MT. Variant merozoite protein expression is associated with erythrocyte invasion phenotypes in Plasmodium falciparum isolates from Tanzania. Molecular and Biochemical Parasitology. 153: 66-71. PMID 17303262 DOI: 10.1016/J.Molbiopara.2007.01.007  0.48
2007 Volkman SK, Sabeti PC, DeCaprio D, Neafsey DE, Schaffner SF, Milner DA, Daily JP, Sarr O, Ndiaye D, Ndir O, Mboup S, Duraisingh MT, Lukens A, Derr A, Stange-Thomann N, et al. A genome-wide map of diversity in Plasmodium falciparum. Nature Genetics. 39: 113-9. PMID 17159979 DOI: 10.1038/Ng1930  0.48
2006 Artavanis-Tsakonas K, Misaghi S, Comeaux CA, Catic A, Spooner E, Duraisingh MT, Ploegh HL. Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum Molecular Microbiology. 61: 1187-1195. PMID 16925553 DOI: 10.1111/J.1365-2958.2006.05307.X  0.48
2006 Duraisingh M, Ferdig MT, Stoeckert CJ, Volkman SK, McGovern VP. Plasmodium research in the postgenomic era. Trends in Parasitology. 22: 1-4. PMID 16311071 DOI: 10.1016/J.Pt.2005.11.011  0.48
2005 Stubbs J, Simpson KM, Triglia T, Plouffe D, Tonkin CJ, Duraisingh MT, Maier AG, Winzeler EA, Cowman AF. Molecular mechanism for switching of P. falciparum invasion pathways into human erythrocytes. Science (New York, N.Y.). 309: 1384-7. PMID 16123303 DOI: 10.1126/Science.1115257  0.48
2005 Duraisingh MT, Refour P. Multiple drug resistance genes in malaria -- from epistasis to epidemiology. Molecular Microbiology. 57: 874-7. PMID 16091030 DOI: 10.1111/J.1365-2958.2005.04748.X  0.48
2005 Duraisingh MT, Cowman AF. Contribution of the pfmdr1 gene to antimalarial drug-resistance. Acta Tropica. 94: 181-90. PMID 15876420 DOI: 10.1016/J.Actatropica.2005.04.008  0.36
2005 Duraisingh MT, Voss TS, Marty AJ, Duffy MF, Good RT, Thompson JK, Freitas-Junior LH, Scherf A, Crabb BS, Cowman AF. Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum. Cell. 121: 13-24. PMID 15820675 DOI: 10.1016/J.Cell.2005.01.036  0.48
2005 Triglia T, Duraisingh MT, Good RT, Cowman AF. Reticulocyte-binding protein homologue 1 is required for sialic acid-dependent invasion into human erythrocytes by Plasmodium falciparum. Molecular Microbiology. 55: 162-74. PMID 15612925 DOI: 10.1111/J.1365-2958.2004.04388.X  0.36
2003 Duraisingh MT, Maier AG, Triglia T, Cowman AF. Erythrocyte-binding antigen 175 mediates invasion in Plasmodium falciparum utilizing sialic acid-dependent and -independent pathways. Proceedings of the National Academy of Sciences of the United States of America. 100: 4796-801. PMID 12672957 DOI: 10.1073/Pnas.0730883100  0.36
2003 Duraisingh MT, Triglia T, Ralph SA, Rayner JC, Barnwell JW, McFadden GI, Cowman AF. Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes. The Embo Journal. 22: 1047-57. PMID 12606570 DOI: 10.1093/Emboj/Cdg096  0.48
2003 Gilberger TW, Thompson JK, Triglia T, Good RT, Duraisingh MT, Cowman AF. A novel erythrocyte binding antigen-175 paralogue from Plasmodium falciparum defines a new trypsin-resistant receptor on human erythrocytes. The Journal of Biological Chemistry. 278: 14480-6. PMID 12556470 DOI: 10.1074/Jbc.M211446200  0.36
2003 Maier AG, Duraisingh MT, Reeder JC, Patel SS, Kazura JW, Zimmerman PA, Cowman AF. Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations. Nature Medicine. 9: 87-92. PMID 12469115 DOI: 10.1038/Nm807  0.48
2002 Baldi DL, Good R, Duraisingh MT, Crabb BS, Cowman AF. Identification and disruption of the gene encoding the third member of the low-molecular-mass rhoptry complex in Plasmodium falciparum. Infection and Immunity. 70: 5236-45. PMID 12183575 DOI: 10.1128/Iai.70.9.5236-5245.2002  0.36
2002 Sangster N, Batterham P, Chapman HD, Duraisingh M, Le Jambre L, Shirley M, Upcroft J, Upcroft P. Resistance to antiparasitic drugs: the role of molecular diagnosis. International Journal For Parasitology. 32: 637-53. PMID 11943235 DOI: 10.1016/S0020-7519(01)00365-4  0.48
2002 O'Donnell RA, Freitas-Junior LH, Preiser PR, Williamson DH, Duraisingh M, McElwain TF, Scherf A, Cowman AF, Crabb BS. A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes. The Embo Journal. 21: 1231-9. PMID 11867551 DOI: 10.1093/Emboj/21.5.1231  0.48
2002 Duraisingh MT, Triglia T, Cowman AF. Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination. International Journal For Parasitology. 32: 81-9. PMID 11796125 DOI: 10.1016/S0020-7519(01)00345-9  0.36
2002 Cowman AF, Duraisingh M, O'Donnell RA, Triglia T, Crabb BS. Functional analysis of the Plasmodium falciparum genome using transfection Methods in Microbiology. 33: 383-396. DOI: 10.1016/S0580-9517(02)33021-6  0.36
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