Jose R. Conejo-Garcia - Publications

Affiliations: 
Immunology and Microbiology Dartmouth College, Hanover, NH, United States 
Area:
Immunology, Molecular Biology, Oncology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cao Y, Trillo-Tinoco J, Sierra RA, Anadon C, Dai W, Mohamed E, Cen L, Costich TL, Magliocco A, Marchion D, Klar R, Michel S, Jaschinski F, Reich RR, Mehrotra S, ... ... Conejo-Garcia JR, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nature Communications. 10: 1280. PMID 30894532 DOI: 10.1038/s41467-019-09263-1  0.64
2018 Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, Lapek JD, Zhang L, Wang WB, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, et al. Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer. Cell. 175: 679-694.e22. PMID 30340040 DOI: 10.1016/j.cell.2018.09.004  0.44
2018 Song M, Sandoval TA, Chae CS, Chopra S, Tan C, Rutkowski MR, Raundhal M, Chaurio RA, Payne KK, Konrad C, Bettigole SE, Shin HR, Crowley MJP, Cerliani JP, Kossenkov AV, ... ... Conejo-Garcia JR, et al. IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Nature. PMID 30305738 DOI: 10.1038/s41586-018-0597-x  0.64
2018 Perales-Puchalt A, Perez-Sanz J, Payne KK, Svoronos N, Allegrezza MJ, Chaurio RA, Anadon C, Calmette J, Biswas S, Mine JA, Costich TL, Nickels L, Wickramasinghe J, Rutkowski MR, Conejo-Garcia JR. Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy. Journal of Leukocyte Biology. PMID 29537705 DOI: 10.1002/JLB.5HI1117-446RR  0.64
2017 Tchou J, Zhao Y, Levine BL, Zhang PJ, Davis MM, Melenhorst JJ, Kulikovskaya I, Brennan AL, Liu X, Lacey SF, Posey A, Williams AD, So A, Conejo-Garcia JR, Plesa G, et al. Safety and efficacy of intratumoral injections of chimeric antigen receptor (CAR) T cells in metastatic breast cancer. Cancer Immunology Research. PMID 29109077 DOI: 10.1158/2326-6066.CIR-17-0189  0.48
2016 Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Perales-Puchalt A, Nguyen JM, Payne KK, Singhal S, Eruslanov EB, Tchou J, Conejo-Garcia JR. Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis. Cancer Research. 76: 6253-6265. PMID 27803104 DOI: 10.1158/0008-5472.CAN-16-1308  0.64
2016 Svoronos N, Perales-Puchalt A, Allegrezza MJ, Rutkowski MR, Payne KK, Tesone AJ, Nguyen JM, Curiel TJ, Cadungog MG, Singhal S, Eruslanov EB, Zhang P, Tchou J, Zhang R, Conejo-Garcia JR. Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Supressor Cells. Cancer Discovery. PMID 27694385 DOI: 10.1158/2159-8290.CD-16-0502  0.64
2016 Zhu H, Bengsch F, Svoronos N, Rutkowski MR, Bitler BG, Allegrezza MJ, Yokoyama Y, Kossenkov AV, Bradner JE, Conejo-Garcia JR, Zhang R. BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression. Cell Reports. 16: 2829-2837. PMID 27626654 DOI: 10.1016/j.celrep.2016.08.032  0.64
2016 Perales-Puchalt A, Svoronos N, Rutkowski MR, Allegrezza MJ, Tesone AJ, Payne KK, Wickramasinghe J, Nguyen JM, O'Brien SW, Gumireddy K, Huang Q, Cadungog M, Connolly DC, Tchou J, Curiel TJ, ... Conejo-Garcia JR, et al. FOLLICLE-STIMULATING HORMONE RECEPTOR IS EXPRESSED BY MOST OVARIAN CANCER SUBTYPES AND IS A SAFE AND EFFECTIVE IMMUNOTHERAPEUTIC TARGET. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27435394 DOI: 10.1158/1078-0432.CCR-16-0492  0.64
2016 Mari ER, Rasouli J, Ciric B, Moore JN, Conejo-Garcia JR, Rajasagi N, Zhang GX, Rabinovich GA, Rostami A. Galectin-1 is essential for the induction of MOG35-55 -based intravenous tolerance in experimental autoimmune encephalomyelitis. European Journal of Immunology. PMID 27151444 DOI: 10.1002/eji.201546212  0.64
2016 Conejo-Garcia JR, Rutkowski MR, Cubillos-Ruiz JR. State-of-the-art of regulatory dendritic cells in cancer. Pharmacology & Therapeutics. PMID 27118338 DOI: 10.1016/j.pharmthera.2016.04.003  0.64
2016 Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Tesone AJ, Perales-Puchalt A, Nguyen JM, Sarmin F, Sheen MR, Jeng EK, Tchou J, Wong HC, Fiering SN, Conejo-Garcia JR. IL-15 AGONISTS OVERCOME THE IMMUNOSUPPRESSIVE EFFECTS OF MEK INHIBITORS. Cancer Research. PMID 26980764 DOI: 10.1158/0008-5472.CAN-15-2808  0.64
2016 Tesone AJ, Rutkowski MR, Brencicova E, Svoronos N, Perales-Puchalt A, Stephen TL, Allegrezza MJ, Payne KK, Nguyen JM, Wickramasinghe J, Tchou J, Borowsky ME, Rabinovich GA, Kossenkov AV, Conejo-Garcia JR. Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells. Cell Reports. PMID 26876172 DOI: 10.1016/j.celrep.2016.01.056  0.64
2015 Sheen MR, Warner SL, Fields JL, Conejo-Garcia JR, Fiering S. Myristoylated p110α Causes Embryonic Death Due to Developmental and Vascular Defects. Open Life Sciences. 10: 461-478. PMID 27482546 DOI: 10.1515/biol-2015-0048  0.4
2015 Conejo-Garcia JR, Rutkowski MR. Small but Mighty: Selected Commensal Bacterial Species Determine the Effectiveness of Anti-cancer Immunotherapies. Immunity. 43: 1037-9. PMID 26682980 DOI: 10.1016/j.immuni.2015.11.014  0.64
2015 Wang Z, Deng Z, Dahmane N, Tsai K, Wang P, Williams DR, Kossenkov AV, Showe LC, Zhang R, Huang Q, Conejo-Garcia JR, Lieberman PM. Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes. Proceedings of the National Academy of Sciences of the United States of America. 112: E6293-E6300. PMID 26578789 DOI: 10.1073/pnas.1505962112  0.64
2015 Rutkowski MR, Conejo-Garcia JR. TLR5 signaling, commensal microbiota and systemic tumor promoting inflammation: the three parcae of malignant progression. Oncoimmunology. 4: e1021542. PMID 26405577 DOI: 10.1080/2162402X.2015.1021542  0.64
2015 Rutkowski MR, Svoronos N, Perales-Puchalt A, Conejo-Garcia JR. The Tumor Macroenvironment: Cancer-Promoting Networks Beyond Tumor Beds. Advances in Cancer Research. 128: 235-62. PMID 26216635 DOI: 10.1016/bs.acr.2015.04.011  0.64
2015 Cubillos-Ruiz JR, Silberman PC, Rutkowski MR, Chopra S, Perales-Puchalt A, Song M, Zhang S, Bettigole SE, Gupta D, Holcomb K, Ellenson LH, Caputo T, Lee AH, Conejo-Garcia JR, Glimcher LH. ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis. Cell. 161: 1527-38. PMID 26073941 DOI: 10.1016/j.cell.2015.05.025  0.64
2015 Rutkowski MR, Conejo-Garcia JR. Size does not matter: commensal microorganisms forge tumor-promoting inflammation and anti-tumor immunity. Oncoscience. 2: 239-46. PMID 25897427  0.64
2015 Villarreal DO, Svoronos N, Wise MC, Shedlock DJ, Morrow MP, Conejo-Garcia JR, Weiner DB. Molecular adjuvant IL-33 enhances the potency of a DNA vaccine in a lethal challenge model. Vaccine. PMID 25887087 DOI: 10.1016/j.vaccine.2015.03.086  0.64
2015 Bitler BG, Aird KM, Garipov A, Li H, Amatangelo M, Kossenkov AV, Schultz DC, Liu Q, Shih IeM, Conejo-Garcia JR, Speicher DW, Zhang R. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nature Medicine. 21: 231-8. PMID 25686104 DOI: 10.1038/nm.3799  0.64
2015 Rutkowski MR, Stephen TL, Svoronos N, Allegrezza MJ, Tesone AJ, Perales-Puchalt A, Brencicova E, Escovar-Fadul X, Nguyen JM, Cadungog MG, Zhang R, Salatino M, Tchou J, Rabinovich GA, Conejo-Garcia JR. Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation. Cancer Cell. 27: 27-40. PMID 25533336 DOI: 10.1016/j.ccell.2014.11.009  0.64
2014 Stephen TL, Rutkowski MR, Allegrezza MJ, Perales-Puchalt A, Tesone AJ, Svoronos N, Nguyen JM, Sarmin F, Borowsky ME, Tchou J, Conejo-Garcia JR. Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. Immunity. 41: 427-39. PMID 25238097 DOI: 10.1016/j.immuni.2014.08.012  0.64
2014 Rutkowski MR, Allegrezza MJ, Svoronos N, Tesone AJ, Stephen TL, Perales-Puchalt A, Nguyen J, Zhang PJ, Fiering SN, Tchou J, Conejo-Garcia JR. Initiation of metastatic breast carcinoma by targeting of the ductal epithelium with adenovirus-cre: a novel transgenic mouse model of breast cancer. Journal of Visualized Experiments : Jove. PMID 24748051 DOI: 10.3791/51171  0.64
2014 Toraya-Brown S, Sheen MR, Zhang P, Chen L, Baird JR, Demidenko E, Turk MJ, Hoopes PJ, Conejo-Garcia JR, Fiering S. Local hyperthermia treatment of tumors induces CD8(+) T cell-mediated resistance against distal and secondary tumors. Nanomedicine : Nanotechnology, Biology, and Medicine. 10: 1273-85. PMID 24566274 DOI: 10.1016/j.nano.2014.01.011  0.64
2013 Cubillos-Ruiz JR, Rutkowski MR, Tchou J, Conejo-Garcia JR. Reprogramming immune responses via microRNA modulation. Microrna Diagnostics and Therapeutics. 1. PMID 25285232 DOI: 10.2478/micrnat-2013-0001  0.64
2013 Baird JR, Fox BA, Sanders KL, Lizotte PH, Cubillos-Ruiz JR, Scarlett UK, Rutkowski MR, Conejo-Garcia JR, Fiering S, Bzik DJ. Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. Cancer Research. 73: 3842-51. PMID 23704211 DOI: 10.1158/0008-5472.CAN-12-1974  0.64
2013 Toraya-Brown S, Sheen MR, Baird JR, Barry S, Demidenko E, Turk MJ, Hoopes PJ, Conejo-Garcia JR, Fiering S. Phagocytes mediate targeting of iron oxide nanoparticles to tumors for cancer therapy. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 159-71. PMID 22935885 DOI: 10.1039/c2ib20180a  0.64
2012 Scarlett UK, Conejo-Garcia JR. Modulating the tumor immune microenvironment as an ovarian cancer treatment strategy. Expert Review of Obstetrics & Gynecology. 7: 413-419. PMID 24039628 DOI: 10.1586/eog.12.41  0.64
2012 Cubillos-Ruiz JR, Sempere LF, Conejo-Garcia JR. Good things come in small packages: Therapeutic anti-tumor immunity induced by microRNA nanoparticles. Oncoimmunology. 1: 968-970. PMID 23162774 DOI: 10.4161/onci.20020  0.64
2012 Rutkowski MR, Stephen TL, Conejo-Garcia JR. Anti-tumor immunity: myeloid leukocytes control the immune landscape. Cellular Immunology. 278: 21-6. PMID 23121972 DOI: 10.1016/j.cellimm.2012.06.014  0.64
2012 Hampton TH, Ballok AE, Bomberger JM, Rutkowski MR, Barnaby R, Coutermarsh B, Conejo-Garcia JR, O'Toole GA, Stanton BA. Does the F508-CFTR mutation induce a proinflammatory response in human airway epithelial cells? American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L509-18. PMID 22821996 DOI: 10.1152/ajplung.00226.2011  0.64
2012 Wasiuk A, Dalton DK, Schpero WL, Stan RV, Conejo-Garcia JR, Noelle RJ. Mast cells impair the development of protective anti-tumor immunity. Cancer Immunology, Immunotherapy : Cii. 61: 2273-82. PMID 22684520 DOI: 10.1007/s00262-012-1276-7  0.64
2012 Scarlett UK, Conejo-Garcia JR. Double agents in the war on cancer: leukocytes govern ovarian cancer progression. Oncotarget. 3: 226-7. PMID 22538964 DOI: 10.18632/oncotarget.478  0.64
2012 Scarlett UK, Rutkowski MR, Rauwerdink AM, Fields J, Escovar-Fadul X, Baird J, Cubillos-Ruiz JR, Jacobs AC, Gonzalez JL, Weaver J, Fiering S, Conejo-Garcia JR. Ovarian cancer progression is controlled by phenotypic changes in dendritic cells. The Journal of Experimental Medicine. 209: 495-506. PMID 22351930 DOI: 10.1084/jem.20111413  0.64
2012 Cubillos-Ruiz JR, Baird JR, Tesone AJ, Rutkowski MR, Scarlett UK, Camposeco-Jacobs AL, Anadon-Arnillas J, Harwood NM, Korc M, Fiering SN, Sempere LF, Conejo-Garcia JR. Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. Cancer Research. 72: 1683-93. PMID 22307839 DOI: 10.1158/0008-5472.CAN-11-3160  0.64
2011 Cubillos-Ruiz JR, Conejo-Garcia JR. It never rains but it pours: potential role of butyrophilins in inhibiting anti-tumor immune responses. Cell Cycle (Georgetown, Tex.). 10: 368-9. PMID 21270530 DOI: 10.4161/cc.10.3.14565  0.64
2010 Cubillos-Ruiz JR, Martinez D, Scarlett UK, Rutkowski MR, Nesbeth YC, Camposeco-Jacobs AL, Conejo-Garcia JR. CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells. Oncotarget. 1: 329-38. PMID 21113407 DOI: 10.18632/oncotarget.165  0.64
2010 Sempere LF, Preis M, Yezefski T, Ouyang H, Suriawinata AA, Silahtaroglu A, Conejo-Garcia JR, Kauppinen S, Wells W, Korc M. Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4246-55. PMID 20682703 DOI: 10.1158/1078-0432.CCR-10-1152  0.52
2010 Nesbeth YC, Martinez DG, Toraya S, Scarlett UK, Cubillos-Ruiz JR, Rutkowski MR, Conejo-Garcia JR. CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 5654-62. PMID 20400704 DOI: 10.4049/jimmunol.0903247  0.64
2010 Robinson RT, Khader SA, Martino CA, Fountain JJ, Teixeira-Coelho M, Pearl JE, Smiley ST, Winslow GM, Woodland DL, Walter MJ, Conejo-Garcia JR, Gubler U, Cooper AM. Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rbeta1 isoform that enhances DC migration. The Journal of Experimental Medicine. 207: 591-605. PMID 20212068 DOI: 10.1084/jem.20091085  0.64
2010 Cubillos-Ruiz JR, Rutkowski M, Conejo-Garcia JR. Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes. Cell Cycle (Georgetown, Tex.). 9: 260-8. PMID 20023378 DOI: 10.4161/cc.9.2.10430  0.64
2009 Cubillos-Ruiz JR, Fiering S, Conejo-Garcia JR. Nanomolecular targeting of dendritic cells for ovarian cancer therapy. Future Oncology (London, England). 5: 1189-92. PMID 19852731 DOI: 10.2217/fon.09.101  0.64
2009 Scarlett UK, Cubillos-Ruiz JR, Nesbeth YC, Martinez DG, Engle X, Gewirtz AT, Ahonen CL, Conejo-Garcia JR. In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells. Cancer Research. 69: 7329-37. PMID 19738057 DOI: 10.1158/0008-5472.CAN-09-0835  0.64
2009 Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR. Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. The Journal of Clinical Investigation. 119: 2231-44. PMID 19620771 DOI: 10.1172/JCI37716  0.64
2009 Nesbeth Y, Scarlett U, Cubillos-Ruiz J, Martinez D, Engle X, Turk MJ, Conejo-Garcia JR. CCL5-mediated endogenous antitumor immunity elicited by adoptively transferred lymphocytes and dendritic cell depletion. Cancer Research. 69: 6331-8. PMID 19602595 DOI: 10.1158/0008-5472.CAN-08-4329  0.64
2009 Pulaski HL, Spahlinger G, Silva IA, McLean K, Kueck AS, Reynolds RK, Coukos G, Conejo-Garcia JR, Buckanovich RJ. Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer. Journal of Translational Medicine. 7: 49. PMID 19545375 DOI: 10.1186/1479-5876-7-49  0.64
2008 Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Buckanovich RJ, Benencia F, Stan RV, Keler T, Sarobe P, Sentman CL, Conejo-Garcia JR. Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity. Cancer Research. 68: 7684-91. PMID 18768667 DOI: 10.1158/0008-5472.CAN-08-1167  0.64
2008 Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Engle XA, Rigby WF, Pioli PA, Guyre PM, Conejo-Garcia JR. PILAR is a novel modulator of human T-cell expansion. Blood. 112: 1259-68. PMID 18550855 DOI: 10.1182/blood-2007-12-130773  0.64
2007 Bak SP, Walters JJ, Takeya M, Conejo-Garcia JR, Berwin BL. Scavenger receptor-A-targeted leukocyte depletion inhibits peritoneal ovarian tumor progression. Cancer Research. 67: 4783-9. PMID 17510407 DOI: 10.1158/0008-5472.CAN-06-4410  0.64
2006 Buckanovich RJ, Sasaroli D, O'brien-Jenkins A, Botbyl J, Conejo-Garcia JR, Benencia F, Liotta LA, Gimotty PA, Coukos G. Use of immuno-LCM to identify the in situ expression profile of cellular constituents of the tumor microenvironment. Cancer Biology & Therapy. 5: 635-42. PMID 16627987  0.64
2004 Conejo-Garcia JR, Benencia F, Courreges MC, Kang E, Mohamed-Hadley A, Buckanovich RJ, Holtz DO, Jenkins A, Na H, Zhang L, Wagner DS, Katsaros D, Caroll R, Coukos G. Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A. Nature Medicine. 10: 950-8. PMID 15334073 DOI: 10.1038/nm1097  0.64
2004 Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, Evdemon-Hogan M, Conejo-Garcia JR, Zhang L, Burow M, Zhu Y, Wei S, Kryczek I, Daniel B, Gordon A, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nature Medicine. 10: 942-9. PMID 15322536 DOI: 10.1038/nm1093  0.64
2004 Conejo-Garcia JR, Benencia F, Courreges MC, Gimotty PA, Khang E, Buckanovich RJ, Frauwirth KA, Zhang L, Katsaros D, Thompson CB, Levine B, Coukos G. Ovarian carcinoma expresses the NKG2D ligand Letal and promotes the survival and expansion of CD28- antitumor T cells. Cancer Research. 64: 2175-82. PMID 15026360 DOI: 10.1158/0008-5472.CAN-03-2194  0.64
2003 Zhang L, Conejo-Garcia JR, Katsaros D, Gimotty PA, Massobrio M, Regnani G, Makrigiannakis A, Gray H, Schlienger K, Liebman MN, Rubin SC, Coukos G. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. The New England Journal of Medicine. 348: 203-13. PMID 12529460 DOI: 10.1056/NEJMoa020177  0.64
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