Christopher F. Basler - Publications

Affiliations: 
Microbiology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Microbiology Biology

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Amarasinghe GK, Ayllón MA, Bào Y, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chabi-Jesus C, Chandran K, Chiapponi C, Crozier I, et al. Taxonomy of the order Mononegavirales: update 2019. Archives of Virology. PMID 31089958 DOI: 10.1007/s00705-019-04247-4  0.48
2019 Kuhn JH, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Crozier I, Dolnik O, Dye JM, Formenty PBH, Griffiths A, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, et al. ICTV Virus Taxonomy Profile: Filoviridae. The Journal of General Virology. PMID 31021739 DOI: 10.1099/jgv.0.001252  0.48
2019 Maes P, Amarasinghe GK, Ayllón MA, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chandran K, Crozier I, de Swart RL, Dietzgen RG, et al. Taxonomy of the order Mononegavirales: second update 2018. Archives of Virology. PMID 30663023 DOI: 10.1007/s00705-018-04126-4  0.48
2018 Basler CF, Krogan NJ, Leung DW, Amarasinghe GK. Virus and host interactions critical for filoviral RNA synthesis as therapeutic targets. Antiviral Research. PMID 30550800 DOI: 10.1016/j.antiviral.2018.12.006  0.48
2018 Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, ... ... Basler CF, et al. Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication. Cell. 175: 1917-1930.e13. PMID 30550789 DOI: 10.1016/j.cell.2018.08.044  0.48
2018 Edwards MR, Liu H, Shabman RS, Ginell GM, Luthra P, Ramanan P, Keefe LJ, Köllner B, Amarasinghe GK, Taylor DJ, Leung DW, Basler CF. Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes. Cell Reports. 24: 861-872.e6. PMID 30044983 DOI: 10.1016/j.celrep.2018.06.045  0.48
2018 Amarasinghe GK, Aréchiga Ceballos NG, Banyard AC, Basler CF, Bavari S, Bennett AJ, Blasdell KR, Briese T, Bukreyev A, Caì Y, Calisher CH, Campos Lawson C, Chandran K, Chapman CA, Chiu CY, et al. Taxonomy of the order Mononegavirales: update 2018. Archives of Virology. PMID 29637429 DOI: 10.1007/s00705-018-3814-x  0.48
2018 Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Ge P, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, et al. Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly. Cell. 172: 966-978.e12. PMID 29474922 DOI: 10.1016/j.cell.2018.02.009  0.48
2017 Olejnik J, Hume AJ, Leung DW, Amarasinghe GK, Basler CF, Mühlberger E. Filovirus Strategies to Escape Antiviral Responses. Current Topics in Microbiology and Immunology. PMID 28685291 DOI: 10.1007/82_2017_13  0.48
2017 Chatterjee S, Luthra P, Esaulova E, Agapov E, Yen BC, Borek DM, Edwards MR, Mittal A, Jordan DS, Ramanan P, Moore ML, Pappu RV, Holtzman MJ, Artyomov MN, Basler CF, et al. Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses. Nature Microbiology. 2: 17101. PMID 28665409 DOI: 10.1038/nmicrobiol.2017.101  0.48
2017 Xu W, Luthra P, Wu C, Batra J, Leung DW, Basler CF, Amarasinghe GK. Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis. Nature Communications. 8: 15576. PMID 28593988 DOI: 10.1038/ncomms15576  0.48
2017 Bào Y, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Dolnik O, Dye JM, Ebihara H, Formenty P, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, Netesov SV, et al. Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses. Viruses. 9. PMID 28492506 DOI: 10.3390/v9050106  0.48
2017 Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, Blasdell KR, Bochnowski A, Briese T, Bukreyev A, Calisher CH, Chandran K, Collins PL, Dietzgen RG, Dolnik O, et al. Taxonomy of the order Mononegavirales: update 2017. Archives of Virology. PMID 28389807 DOI: 10.1007/s00705-017-3311-7  0.48
2017 Liu G, Nash PJ, Johnson B, Pietzsch C, Ilagan MG, Bukreyev A, Basler CF, Bowlin TL, Moir DT, Leung DW, Amarasinghe GK. A Sensitive In Vitro High-Throughput Screen to Identify Pan-Filoviral Replication Inhibitors Targeting the VP35-NP Interface. Acs Infectious Diseases. PMID 28152588 DOI: 10.1021/acsinfecdis.6b00209  0.48
2016 Schwarz TM, Edwards MR, Diederichs A, Alinger JB, Leung DW, Amarasinghe GK, Basler CF. VP24-karyopherin alpha binding affinities differ between Ebolavirus species influencing interferon inhibition and VP24 stability. Journal of Virology. PMID 27974555 DOI: 10.1128/JVI.01715-16  0.48
2016 Postler TS, Clawson AN, Amarasinghe GK, Basler CF, Bavari S, Benkő M, Blasdell KR, Briese T, Buchmeier MJ, Bukreyev A, Calisher CH, Chandran K, Charrel R, Clegg CS, Collins PL, et al. Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials. Systematic Biology. PMID 27798405 DOI: 10.1093/sysbio/syw096  0.48
2016 Johnson B, Li J, Adhikari J, Edwards MR, Zhang H, Schwarz T, Leung DW, Basler CF, Gross ML, Amarasinghe GK. Dimerization controls Marburg virus VP24-dependent modulation of host antioxidative stress responses. Journal of Molecular Biology. PMID 27497688 DOI: 10.1016/j.jmb.2016.07.020  0.48
2016 Chatterjee S, Basler CF, Amarasinghe GK, Leung DW. Molecular mechanisms of innate immune inhibition by non-segmented negative-sense RNA viruses. Journal of Molecular Biology. PMID 27487481 DOI: 10.1016/j.jmb.2016.07.017  0.48
2016 Afonso CL, Amarasinghe GK, Bányai K, Bào Y, Basler CF, Bavari S, Bejerman N, Blasdell KR, Briand FX, Briese T, Bukreyev A, Calisher CH, Chandran K, Chéng J, Clawson AN, et al. Taxonomy of the order Mononegavirales: update 2016. Archives of Virology. PMID 27216929 DOI: 10.1007/s00705-016-2880-1  0.48
2016 Edwards MR, Liu G, Mire CE, Sureshchandra S, Luthra P, Yen B, Shabman RS, Leung DW, Messaoudi I, Geisbert TW, Amarasinghe GK, Basler CF. Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins. Cell Reports. PMID 26876165 DOI: 10.1016/j.celrep.2016.01.049  0.48
2016 Esposito AM, Cheung P, Swartz TH, Li H, Tsibane T, Durham ND, Basler CF, Felsenfeld DP, Chen BK. A high throughput Cre-lox activated viral membrane fusion assay identifies pharmacological inhibitors of HIV entry. Virology. 490: 6-16. PMID 26803470 DOI: 10.1016/j.virol.2015.10.013  0.48
2015 Satterfield BA, Cross RW, Fenton KA, Agans KN, Basler CF, Geisbert TW, Mire CE. The immunomodulating V and W proteins of Nipah virus determine disease course. Nature Communications. 6: 7483. PMID 26105519 DOI: 10.1038/ncomms8483  0.48
2015 Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, et al. An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Reports. 11: 376-89. PMID 25865894 DOI: 10.1016/j.celrep.2015.03.034  0.48
2015 Miller MS, Rialdi A, Ho JS, Tilove M, Martinez-Gil L, Moshkina NP, Peralta Z, Noel J, Melegari C, Maestre AM, Mitsopoulos P, Madrenas J, Heinz S, Benner C, Young JA, ... ... Basler CF, et al. Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis. Nature Immunology. 16: 485-94. PMID 25822250 DOI: 10.1038/ni.3132  0.48
2015 Ciancanelli MJ, Huang SX, Luthra P, Garner H, Itan Y, Volpi S, Lafaille FG, Trouillet C, Schmolke M, Albrecht RA, Israelsson E, Lim HK, Casadio M, Hermesh T, Lorenzo L, ... ... Basler CF, et al. Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency. Science (New York, N.Y.). 348: 448-53. PMID 25814066 DOI: 10.1126/science.aaa1578  0.48
2015 Luthra P, Jordan DS, Leung DW, Amarasinghe GK, Basler CF. Ebola virus VP35 interaction with dynein LC8 regulates viral RNA synthesis. Journal of Virology. 89: 5148-53. PMID 25741013 DOI: 10.1128/JVI.03652-14  0.48
2014 Shabman RS, Jabado OJ, Mire CE, Stockwell TB, Edwards M, Mahajan M, Geisbert TW, Basler CF. Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells. Mbio. 5: e02011. PMID 25370495 DOI: 10.1128/mBio.02011-14  0.48
2014 Yen B, Mulder LC, Martinez O, Basler CF. Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation. Journal of Virology. 88: 12500-10. PMID 25142601 DOI: 10.1128/JVI.02163-14  0.6
2014 Xu W, Edwards MR, Borek DM, Feagins AR, Mittal A, Alinger JB, Berry KN, Yen B, Hamilton J, Brett TJ, Pappu RV, Leung DW, Basler CF, Amarasinghe GK. Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1. Cell Host & Microbe. 16: 187-200. PMID 25121748 DOI: 10.1016/j.chom.2014.07.008  0.48
2014 Johnson JC, Martinez O, Honko AN, Hensley LE, Olinger GG, Basler CF. Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells. Antiviral Research. 107: 102-9. PMID 24815087 DOI: 10.1016/j.antiviral.2014.04.014  0.48
2014 Edwards MR, Johnson B, Mire CE, Xu W, Shabman RS, Speller LN, Leung DW, Geisbert TW, Amarasinghe GK, Basler CF. The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway. Cell Reports. 6: 1017-25. PMID 24630991 DOI: 10.1016/j.celrep.2014.01.043  0.48
2014 Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito LM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, ... ... Basler CF, et al. In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity. Journal of Molecular Biology. 426: 2045-58. PMID 24495995 DOI: 10.1016/j.jmb.2014.01.010  0.48
2013 Binning JM, Wang T, Luthra P, Shabman RS, Borek DM, Liu G, Xu W, Leung DW, Basler CF, Amarasinghe GK. Development of RNA aptamers targeting Ebola virus VP35 Biochemistry. 52: 8406-8419. PMID 24067086 DOI: 10.1021/bi400704d  0.48
2013 Miller MS, Gardner TJ, Krammer F, Aguado LC, Tortorella D, Basler CF, Palese P. Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis. Science Translational Medicine. 5: 198ra107. PMID 23946196 DOI: 10.1126/scitranslmed.3006637  0.48
2013 Luthra P, Ramanan P, Mire CE, Weisend C, Tsuda Y, Yen B, Liu G, Leung DW, Geisbert TW, Ebihara H, Amarasinghe GK, Basler CF. Mutual antagonism between the ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome Cell Host and Microbe. 14: 74-84. PMID 23870315 DOI: 10.1016/j.chom.2013.06.010  0.48
2013 Shabman RS, Hoenen T, Groseth A, Jabado O, Binning JM, Amarasinghe GK, Feldmann H, Basler CF. An upstream open reading frame modulates ebola virus polymerase translation and virus replication. Plos Pathogens. 9: e1003147. PMID 23382680 DOI: 10.1371/journal.ppat.1003147  0.48
2013 Martinez O, Johnson JC, Honko A, Yen B, Shabman RS, Hensley LE, Olinger GG, Basler CF. Ebola virus exploits a monocyte differentiation program to promote its entry. Journal of Virology. 87: 3801-14. PMID 23345511 DOI: 10.1128/JVI.02695-12  0.48
2013 Martinez O, Ndungo E, Tantral L, Miller EH, Leung LW, Chandran K, Basler CF. A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species- and cell-type-specific manner. Journal of Virology. 87: 3324-34. PMID 23302883 DOI: 10.1128/JVI.01598-12  0.48
2013 Miller MS, Tsibane T, Krammer F, Hai R, Rahmat S, Basler CF, Palese P. 1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans. The Journal of Infectious Diseases. 207: 98-105. PMID 23087428 DOI: 10.1093/infdis/jis652  0.48
2012 Tsibane T, Ekiert DC, Krause JC, Martinez O, Crowe JE, Wilson IA, Basler CF. Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses. Plos Pathogens. 8: e1003067. PMID 23236279 DOI: 10.1371/journal.ppat.1003067  0.48
2012 Ramanan P, Edwards MR, Shabman RS, Leung DW, Endlich-Frazier AC, Borek DM, Otwinowski Z, Liu G, Huh J, Basler CF, Amarasinghe GK. Structural basis for Marburg virus VP35-mediated immune evasion mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 109: 20661-20666. PMID 23185024  0.48
2012 Weisfuse IB, Tsibane T, Konty KJ, Egger JR, Waddell EN, Rahmat S, Harris E, Olson DR, Basler CF. Seroprevalence of pandemic influenza viruses, New York, New York, USA, 2004. Emerging Infectious Diseases. 18: 1905-7. PMID 23092519 DOI: 10.3201/eid1811.120156  0.48
2012 Hoenen T, Shabman RS, Groseth A, Herwig A, Weber M, Schudt G, Dolnik O, Basler CF, Becker S, Feldmann H. Inclusion bodies are a site of ebolavirus replication. Journal of Virology. 86: 11779-88. PMID 22915810 DOI: 10.1128/JVI.01525-12  0.48
2012 Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Albrecht R, Blum DL, Ramos I, Fernandez-Sesma A, Edwards KM, García-Sastre A, Basler CF, Crowe JE. Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. Journal of Virology. 86: 6334-40. PMID 22457520 DOI: 10.1128/JVI.07158-11  0.48
2012 Martinez O, Leung LW, Basler CF. The role of antigen-presenting cells in filoviral hemorrhagic fever: gaps in current knowledge. Antiviral Research. 93: 416-28. PMID 22333482 DOI: 10.1016/j.antiviral.2012.01.011  0.48
2012 Leung DW, Basler CF, Amarasinghe GK. Molecular mechanisms of viral inhibitors of RIG-I-like receptors Trends in Microbiology. 20: 139-146. PMID 22325030 DOI: 10.1016/j.tim.2011.12.005  0.48
2011 Ramanan P, Shabman RS, Brown CS, Amarasinghe GK, Basler CF, Leung DW. Filoviral immune evasion mechanisms Viruses. 3: 1634-1649. PMID 21994800 DOI: 10.3390/v3091634  0.48
2011 Leung LW, Martinez O, Reynard O, Volchkov VE, Basler CF. Ebola virus failure to stimulate plasmacytoid dendritic cell interferon responses correlates with impaired cellular entry. The Journal of Infectious Diseases. 204: S973-7. PMID 21987778 DOI: 10.1093/infdis/jir331  0.48
2011 Shabman RS, Leung DW, Johnson J, Glennon N, Gulcicek EE, Stone KL, Leung L, Hensley L, Amarasinghe GK, Basler CF. DRBP76 associates with Ebola virus VP35 and suppresses viral polymerase function. The Journal of Infectious Diseases. 204: S911-8. PMID 21987769 DOI: 10.1093/infdis/jir343  0.48
2011 Shabman RS, Gulcicek EE, Stone KL, Basler CF. The Ebola virus VP24 protein prevents hnRNP C1/C2 binding to karyopherin α1 and partially alters its nuclear import. The Journal of Infectious Diseases. 204: S904-10. PMID 21987768 DOI: 10.1093/infdis/jir323  0.48
2011 Reynard O, Reid SP, Page A, Mateo M, Alazard-Dany N, Raoul H, Basler CF, Volchkov VE. Unconventional secretion of Ebola virus matrix protein VP40. The Journal of Infectious Diseases. 204: S833-9. PMID 21987759 DOI: 10.1093/infdis/jir305  0.6
2011 Martinez O, Tantral L, Mulherkar N, Chandran K, Basler CF. Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles. The Journal of Infectious Diseases. 204: S825-32. PMID 21987758 DOI: 10.1093/infdis/jir295  0.48
2011 Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Briney BS, Smith SA, Basler CF, Crowe JE. Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. Journal of Immunology (Baltimore, Md. : 1950). 187: 3704-11. PMID 21880983 DOI: 10.4049/jimmunol.1101823  0.48
2011 Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Basler CF, Crowe JE. A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. Journal of Virology. 85: 10905-8. PMID 21849447 DOI: 10.1128/JVI.00700-11  0.48
2011 Vilchèze C, Baughn AD, Tufariello J, Leung LW, Kuo M, Basler CF, Alland D, Sacchettini JC, Freundlich JS, Jacobs WR. Novel inhibitors of InhA efficiently kill Mycobacterium tuberculosis under aerobic and anaerobic conditions. Antimicrobial Agents and Chemotherapy. 55: 3889-98. PMID 21628538 DOI: 10.1128/AAC.00266-11  0.48
2011 Valmas C, Basler CF. Marburg virus VP40 antagonizes interferon signaling in a species-specific manner. Journal of Virology. 85: 4309-17. PMID 21325424 DOI: 10.1128/JVI.02575-10  1
2011 Leung LW, Park MS, Martinez O, Valmas C, López CB, Basler CF. Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells. Immunology and Cell Biology. 89: 792-802. PMID 21263462 DOI: 10.1038/icb.2010.169  0.48
2010 Leung DW, Prins KC, Basler CF, Amarasinghe GK. Ebolavirus VP35 is a multifunctional virulence factor Virulence. 1: 526-531. PMID 21178490 DOI: 10.4161/viru.1.6.12984  0.48
2010 Medina RA, Manicassamy B, Stertz S, Seibert CW, Hai R, Belshe RB, Frey SE, Basler CF, Palese P, García-Sastre A. Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus. Nature Communications. 1: 28. PMID 20975689 DOI: 10.1038/ncomms1026  0.48
2010 Fytas C, Kolocouris A, Fytas G, Zoidis G, Valmas C, Basler CF. Influence of an additional amino group on the potency of aminoadamantanes against influenza virus A. II - Synthesis of spiropiperazines and in vitro activity against influenza A H3N2 virus. Bioorganic Chemistry. 38: 247-51. PMID 20926112 DOI: 10.1016/j.bioorg.2010.09.001  1
2010 Prins KC, Binning JM, Shabman RS, Leung DW, Amarasinghe GK, Basler CF. Basic residues within the ebolavirus VP35 protein are required for its viral polymerase cofactor function Journal of Virology. 84: 10581-10591. PMID 20686031 DOI: 10.1128/JVI.00925-10  0.48
2010 Leung DW, Borek D, Farahbakhsh M, Ramanan P, Nix JC, Wang T, Prins KC, Otwinowski Z, Honzatko RB, Helgeson LA, Basler CF, Amarasinghe GK. Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 66: 689-692. PMID 20516601 DOI: 10.1107/S1744309110013266  0.48
2010 Leung DW, Shabman RS, Farahbakhsh M, Prins KC, Borek DM, Wang T, Mühlberger E, Basler CF, Amarasinghe GK. Structural and functional characterization of Reston Ebola virus VP35 interferon inhibitory domain Journal of Molecular Biology. 399: 347-357. PMID 20399790 DOI: 10.1016/j.jmb.2010.04.022  0.48
2010 Manicassamy B, Medina RA, Hai R, Tsibane T, Stertz S, Nistal-Villán E, Palese P, Basler CF, García-Sastre A. Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines. Plos Pathogens. 6: e1000745. PMID 20126449 DOI: 10.1371/journal.ppat.1000745  0.48
2010 Valmas C, Grosch MN, Schümann M, Olejnik J, Martinez O, Best SM, Krähling V, Basler CF, Mühlberger E. Marburg virus evades interferon responses by a mechanism distinct from ebola virus. Plos Pathogens. 6: e1000721. PMID 20084112 DOI: 10.1371/journal.ppat.1000721  1
2010 Leung DW, Prins KC, Borek DM, Farahbakhsh M, Tufariello JM, Ramanan P, Nix JC, Helgeson LA, Otwinowski Z, Honzatko RB, Basler CF, Amarasinghe GK. Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35 Nature Structural and Molecular Biology. 17: 165-172. PMID 20081868 DOI: 10.1038/nsmb.1765  0.48
2010 Prins KC, Delpeut S, Leung DW, Reynard O, Volchkova VA, Reid SP, Ramanan P, Cárdenas WB, Amarasinghe GK, Volchkov VE, Basler CF. Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs Journal of Virology. 84: 3004-3015. PMID 20071589 DOI: 10.1128/JVI.02459-09  0.48
2010 Krause JC, Tumpey TM, Huffman CJ, McGraw PA, Pearce MB, Tsibane T, Hai R, Basler CF, Crowe JE. Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses. Journal of Virology. 84: 3127-30. PMID 20042511 DOI: 10.1128/JVI.02184-09  0.48
2010 Xu R, McBride R, Paulson JC, Basler CF, Wilson IA. Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. Journal of Virology. 84: 1715-21. PMID 20007271 DOI: 10.1128/JVI.02162-09  0.48
2010 Mateo M, Reid SP, Leung LW, Basler CF, Volchkov VE. Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling. Journal of Virology. 84: 1169-75. PMID 19889762 DOI: 10.1128/JVI.01372-09  0.48
2010 Martinez O, Johnson J, Manicassamy B, Rong L, Olinger GG, Hensley LE, Basler CF. Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition. Cellular Microbiology. 12: 148-57. PMID 19775255 DOI: 10.1111/j.1462-5822.2009.01385.x  0.48
2009 Basler CF, Amarasinghe GK. Evasion of interferon responses by Ebola and Marburg viruses. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 29: 511-20. PMID 19694547 DOI: 10.1089/jir.2009.0076  0.48
2009 Ciancanelli MJ, Volchkova VA, Shaw ML, Volchkov VE, Basler CF. Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism. Journal of Virology. 83: 7828-41. PMID 19515782 DOI: 10.1128/JVI.02610-08  0.48
2009 Martinez O, Tsibane T, Basler CF. Neutralizing anti-influenza virus monoclonal antibodies: therapeutics and tools for discovery. International Reviews of Immunology. 28: 69-92. PMID 19241254 DOI: 10.1080/08830180802593540  0.6
2009 Leung DW, Ginder ND, Nix JC, Basler CF, Honzatko RB, Amarasinghe GK. Expression, purification, crystallization and preliminary X-ray studies of the Ebola VP35 interferon inhibitory domain Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 65: 163-165. PMID 19194011 DOI: 10.1107/S1744309108044187  0.48
2009 Prins KC, Cárdenas WB, Basler CF. Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. Journal of Virology. 83: 3069-77. PMID 19153231 DOI: 10.1128/JVI.01875-08  0.56
2009 Leung DW, Ginder ND, Fulton DB, Nix J, Basler CF, Honzatko RB, Amarasinghe GK. Structure of the Ebola VP35 interferon inhibitory domain Proceedings of the National Academy of Sciences of the United States of America. 106: 411-416. PMID 19122151 DOI: 10.1073/pnas.0807854106  0.48
2008 Aiki-Raji CO, Aguilar PV, Kwon YK, Goetz S, Suarez DL, Jethra AI, Nash O, Adeyefa CA, Adu FD, Swayne D, Basler CF. Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria. Emerging Infectious Diseases. 14: 1753-5. PMID 18976562 DOI: 10.3201/eid1411.080557  0.48
2008 Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, et al. Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature. 455: 532-6. PMID 18716625 DOI: 10.1038/nature07231  0.48
2008 Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cárdenas WB, Yount JS, Moran TM, Basler CF, Komuro A, Horvath CM, Xavier R, Ting AT. The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. Embo Reports. 9: 930-6. PMID 18636086 DOI: 10.1038/embor.2008.136  0.48
2008 Basler CF, Aguilar PV. Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses. Antiviral Research. 79: 166-78. PMID 18547656 DOI: 10.1016/j.antiviral.2008.04.006  0.48
2008 Aguilar PV, Leung LW, Wang E, Weaver SC, Basler CF. A five-amino-acid deletion of the eastern equine encephalitis virus capsid protein attenuates replication in mammalian systems but not in mosquito cells. Journal of Virology. 82: 6972-83. PMID 18480443 DOI: 10.1128/JVI.01283-07  0.48
2008 Pappas C, Aguilar PV, Basler CF, Solórzano A, Zeng H, Perrone LA, Palese P, García-Sastre A, Katz JM, Tumpey TM. Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus. Proceedings of the National Academy of Sciences of the United States of America. 105: 3064-9. PMID 18287069 DOI: 10.1073/pnas.0711815105  0.48
2007 Reid SP, Valmas C, Martinez O, Sanchez FM, Basler CF. Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. Journal of Virology. 81: 13469-77. PMID 17928350 DOI: 10.1128/JVI.01097-07  1
2007 Martinez O, Valmas C, Basler CF. Ebola virus-like particle-induced activation of NF-kappaB and Erk signaling in human dendritic cells requires the glycoprotein mucin domain. Virology. 364: 342-54. PMID 17434557 DOI: 10.1016/j.virol.2007.03.020  1
2007 Aguilar PV, Weaver SC, Basler CF. Capsid protein of eastern equine encephalitis virus inhibits host cell gene expression. Journal of Virology. 81: 3866-76. PMID 17267491 DOI: 10.1128/JVI.02075-06  0.48
2006 Kash JC, Tumpey TM, Proll SC, Carter V, Perwitasari O, Thomas MJ, Basler CF, Palese P, Taubenberger JK, García-Sastre A, Swayne DE, Katze MG. Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature. 443: 578-81. PMID 17006449 DOI: 10.1038/nature05181  0.48
2006 Ciancanelli MJ, Basler CF. Mutation of YMYL in the Nipah virus matrix protein abrogates budding and alters subcellular localization. Journal of Virology. 80: 12070-8. PMID 17005661 DOI: 10.1128/JVI.01743-06  0.32
2006 Cárdenas WB, Loo YM, Gale M, Hartman AL, Kimberlin CR, Martínez-Sobrido L, Saphire EO, Basler CF. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling. Journal of Virology. 80: 5168-78. PMID 16698997 DOI: 10.1128/JVI.02199-05  0.48
2006 Reid SP, Leung LW, Hartman AL, Martinez O, Shaw ML, Carbonnelle C, Volchkov VE, Nichol ST, Basler CF. Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation. Journal of Virology. 80: 5156-67. PMID 16698996 DOI: 10.1128/JVI.02349-05  0.48
2005 Tumpey TM, García-Sastre A, Taubenberger JK, Palese P, Swayne DE, Pantin-Jackwood MJ, Schultz-Cherry S, Solórzano A, Van Rooijen N, Katz JM, Basler CF. Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. Journal of Virology. 79: 14933-44. PMID 16282492 DOI: 10.1128/JVI.79.23.14933-14944.2005  0.48
2005 Tumpey TM, Basler CF, Aguilar PV, Zeng H, Solórzano A, Swayne DE, Cox NJ, Katz JM, Taubenberger JK, Palese P, García-Sastre A. Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science (New York, N.Y.). 310: 77-80. PMID 16210530 DOI: 10.1126/science.1119392  0.48
2005 Glaser L, Stevens J, Zamarin D, Wilson IA, García-Sastre A, Tumpey TM, Basler CF, Taubenberger JK, Palese P. A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. Journal of Virology. 79: 11533-6. PMID 16103207 DOI: 10.1128/JVI.79.17.11533-11536.2005  0.48
2005 Reid SP, Cárdenas WB, Basler CF. Homo-oligomerization facilitates the interferon-antagonist activity of the ebolavirus VP35 protein. Virology. 341: 179-89. PMID 16095644 DOI: 10.1016/j.virol.2005.06.044  0.6
2005 Shaw ML, Cardenas WB, Zamarin D, Palese P, Basler CF. Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways. Journal of Virology. 79: 6078-88. PMID 15857993 DOI: 10.1128/JVI.79.10.6078-6088.2005  0.48
2005 Basler CF, García-Sastre A, Palese P. A novel paramyxovirus? Emerging Infectious Diseases. 11: 108-12. PMID 15705331 DOI: 10.3201/eid1101.040653  0.48
2004 Kash JC, Basler CF, García-Sastre A, Carter V, Billharz R, Swayne DE, Przygodzki RM, Taubenberger JK, Katze MG, Tumpey TM. Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus. Journal of Virology. 78: 9499-511. PMID 15308742 DOI: 10.1128/JVI.78.17.9499-9511.2004  0.48
2004 Shaw ML, García-Sastre A, Palese P, Basler CF. Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively. Journal of Virology. 78: 5633-41. PMID 15140960 DOI: 10.1128/JVI.78.11.5633-5641.2004  0.48
2003 Park MS, García-Sastre A, Cros JF, Basler CF, Palese P. Newcastle disease virus V protein is a determinant of host range restriction. Journal of Virology. 77: 9522-32. PMID 12915566 DOI: 10.1128/JVI.77.17.9522-9532.2003  0.48
2003 Flandorfer A, García-Sastre A, Basler CF, Palese P. Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin. Journal of Virology. 77: 9116-23. PMID 12915528 DOI: 10.1128/JVI.77.17.9116-9123.2003  0.48
2003 Basler CF, Mikulasova A, Martinez-Sobrido L, Paragas J, Mühlberger E, Bray M, Klenk HD, Palese P, García-Sastre A. The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. Journal of Virology. 77: 7945-56. PMID 12829834  0.48
2003 Park MS, Shaw ML, Muñoz-Jordan J, Cros JF, Nakaya T, Bouvier N, Palese P, García-Sastre A, Basler CF. Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins. Journal of Virology. 77: 1501-11. PMID 12502864 DOI: 10.1128/JVI.77.2.1501-1511.2003  0.48
2002 Palese P, Basler CF, García-Sastre A. The makings of a killer. Nature Medicine. 8: 927-8. PMID 12205448 DOI: 10.1038/nm0902-927  0.48
2002 Geiss GK, Salvatore M, Tumpey TM, Carter VS, Wang X, Basler CF, Taubenberger JK, Bumgarner RE, Palese P, Katze MG, García-Sastre A. Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proceedings of the National Academy of Sciences of the United States of America. 99: 10736-41. PMID 12149435 DOI: 10.1073/pnas.112338099  0.48
2002 Salvatore M, Basler CF, Parisien JP, Horvath CM, Bourmakina S, Zheng H, Muster T, Palese P, García-Sastre A. Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis. Journal of Virology. 76: 1206-12. PMID 11773396  0.48
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