Laurence D. Sibley - Publications

Biology & Biomedical Sciences (Molecular Microbiology & Microbial Pathogenesis) Washington University, Saint Louis, St. Louis, MO 
Microbiology Biology, Parasitology Biology, Cell Biology

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Simpson C, Jones NG, Hull-Ryde EA, Kireev D, Stashko M, Tang K, Janetka J, Wildman SA, Zuercher WJ, Schapira M, Hui R, Janzen W, Sibley LD. Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18. Acs Infectious Diseases. 2: 194-206. PMID 27379343 DOI: 10.1021/acsinfecdis.5b00102  0.68
2016 Brown KM, Lourido S, Sibley LD. Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondii. The Journal of Biological Chemistry. PMID 26933037 DOI: 10.1074/jbc.M115.700518  0.68
2015 Kuhlenschmidt TB, Rutaganira FU, Long S, Tang K, Shokat KM, Kuhlenschmidt MS, Sibley LD. Inhibition of Calcium-Dependent Protein Kinase 1 (CDPK1) In Vitro by Pyrazolopyrimidine Derivatives Does Not Correlate with Sensitivity of Cryptosporidium parvum Growth in Cell Culture. Antimicrobial Agents and Chemotherapy. 60: 570-9. PMID 26552986 DOI: 10.1128/AAC.01915-15  0.68
2014 Etheridge RD, Alaganan A, Tang K, Lou HJ, Turk BE, Sibley LD. The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice. Cell Host & Microbe. 15: 537-50. PMID 24832449 DOI: 10.1016/j.chom.2014.04.002  0.68
2014 Alaganan A, Fentress SJ, Tang K, Wang Q, Sibley LD. Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 111: 1126-31. PMID 24390541 DOI: 10.1073/pnas.1313501111  0.68
2013 Lourido S, Jeschke GR, Turk BE, Sibley LD. Exploiting the unique ATP-binding pocket of toxoplasma calcium-dependent protein kinase 1 to identify its substrates. Acs Chemical Biology. 8: 1155-62. PMID 23530747 DOI: 10.1021/cb400115y  0.68
2013 Lourido S, Zhang C, Lopez MS, Tang K, Barks J, Wang Q, Wildman SA, Shokat KM, Sibley LD. Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii. Journal of Medicinal Chemistry. 56: 3068-77. PMID 23470217 DOI: 10.1021/jm4001314  0.68
2012 Lourido S, Tang K, Sibley LD. Distinct signalling pathways control Toxoplasma egress and host-cell invasion. The Embo Journal. 31: 4524-34. PMID 23149386 DOI: 10.1038/emboj.2012.299  0.68
2011 Skillman KM, Diraviyam K, Khan A, Tang K, Sept D, Sibley LD. Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasites. Plos Pathogens. 7: e1002280. PMID 21998582 DOI: 10.1371/journal.ppat.1002280  0.68
2011 Yadav R, Pathak PP, Shukla VK, Jain A, Srivastava S, Tripathi S, Krishna Pulavarti SV, Mehta S, Sibley LD, Arora A. Solution structure and dynamics of ADF from Toxoplasma gondii. Journal of Structural Biology. 176: 97-111. PMID 21820516 DOI: 10.1016/j.jsb.2011.07.011  1
2011 Behnke MS, Khan A, Wootton JC, Dubey JP, Tang K, Sibley LD. Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases. Proceedings of the National Academy of Sciences of the United States of America. 108: 9631-6. PMID 21586633 DOI: 10.1073/pnas.1015338108  0.68
2011 Mehta S, Sibley LD. Actin depolymerizing factor controls actin turnover and gliding motility in Toxoplasma gondii. Molecular Biology of the Cell. 22: 1290-9. PMID 21346192 DOI: 10.1091/mbc.E10-12-0939  1
2010 Fentress SJ, Behnke MS, Dunay IR, Mashayekhi M, Rommereim LM, Fox BA, Bzik DJ, Taylor GA, Turk BE, Lichti CF, Townsend RR, Qiu W, Hui R, Beatty WL, Sibley LD. Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. Cell Host & Microbe. 8: 484-95. PMID 21147463 DOI: 10.1016/j.chom.2010.11.005  0.36
2010 Lourido S, Shuman J, Zhang C, Shokat KM, Hui R, Sibley LD. Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma. Nature. 465: 359-62. PMID 20485436 DOI: 10.1038/nature09022  0.68
2010 Wernimont AK, Artz JD, Finerty P, Lin YH, Amani M, Allali-Hassani A, Senisterra G, Vedadi M, Tempel W, Mackenzie F, Chau I, Lourido S, Sibley LD, Hui R. Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium. Nature Structural & Molecular Biology. 17: 596-601. PMID 20436473 DOI: 10.1038/nsmb.1795  0.68
2010 Mehta S, Sibley LD. Toxoplasma gondii actin depolymerizing factor acts primarily to sequester G-actin. The Journal of Biological Chemistry. 285: 6835-47. PMID 20042603 DOI: 10.1074/jbc.M109.068155  1
2009 Billker O, Lourido S, Sibley LD. Calcium-dependent signaling and kinases in apicomplexan parasites. Cell Host & Microbe. 5: 612-22. PMID 19527888 DOI: 10.1016/j.chom.2009.05.017  0.68
2009 Qiu W, Wernimont A, Tang K, Taylor S, Lunin V, Schapira M, Fentress S, Hui R, Sibley LD. Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii. The Embo Journal. 28: 969-79. PMID 19197235 DOI: 10.1038/emboj.2009.24  0.68
2006 Taylor S, Barragan A, Su C, Fux B, Fentress SJ, Tang K, Beatty WL, Hajj HE, Jerome M, Behnke MS, White M, Wootton JC, Sibley LD. A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii. Science (New York, N.Y.). 314: 1776-80. PMID 17170305 DOI: 10.1126/science.1133643  0.68
2005 Khan A, Taylor S, Su C, Mackey AJ, Boyle J, Cole R, Glover D, Tang K, Paulsen IT, Berriman M, Boothroyd JC, Pfefferkorn ER, Dubey JP, Ajioka JW, Roos DS, ... ... Sibley LD, et al. Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Research. 33: 2980-92. PMID 15911631 DOI: 10.1093/nar/gki604  0.68
2004 Omoto CK, Toso M, Tang K, Sibley LD. Expressed sequence tag (EST) analysis of Gregarine gametocyst development. International Journal For Parasitology. 34: 1265-71. PMID 15491589 DOI: 10.1016/j.ijpara.2004.08.004  0.68
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