Stanislaw F. Wnuk - Publications

Affiliations: 
Florida International University, Miami, FL, United States 
Area:
Biochemistry, Organic Chemistry, Microbiology Biology

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zhao L, Doddipatla S, Kaiser RI, Lu W, Kostko O, Ahmed M, Tuli LB, Morozov AN, Howlader AH, Wnuk SF, Mebel AM, Azyazov VN, Mohamed RK, Fischer FR. Gas-phase synthesis of corannulene - a molecular building block of fullerenes. Physical Chemistry Chemical Physics : Pccp. PMID 33595573 DOI: 10.1039/d0cp06537d  0.76
2020 Mudgal M, Dang TP, Sobczak AJ, Lumpuy DA, Dutta P, Ward S, Ward K, Alahmadi M, Kumar A, Sevilla MD, Wnuk SF, Adhikary A. Site of Azido Substitution in the Sugar Moiety of Azidopyrimidine Nucleosides Influences the Reactivity of Aminyl Radicals Formed by Dissociative Electron Attachment. The Journal of Physical Chemistry. B. PMID 33270461 DOI: 10.1021/acs.jpcb.0c08201  0.8
2020 Zhao L, Kaiser RI, Lu W, Kostko O, Ahmed M, Evseev MM, Bashkirov EK, Oleinikov AD, Azyazov VN, Mebel AM, Howlader AH, Wnuk SF. Gas phase formation of cyclopentanaphthalene (benzindene) isomers reactions of 5- and 6-indenyl radicals with vinylacetylene. Physical Chemistry Chemical Physics : Pccp. PMID 32996974 DOI: 10.1039/d0cp03846f  0.76
2020 Suzol SH, Hasan Howlader A, Galván AE, Radhakrishnan M, Wnuk SF, Rosen BP, Yoshinaga M. Semisynthesis of the Organoarsenical Antibiotic Arsinothricin. Journal of Natural Products. PMID 32830503 DOI: 10.1021/acs.jnatprod.0c00522  0.76
2020 Zhao L, Kaiser RI, Lu W, Ahmed M, Oleinikov AD, Azyazov VN, Mebel AM, Howlader AH, Wnuk SF. Gas phase formation of phenalene via 10π-aromatic, resonantly stabilized free radical intermediates. Physical Chemistry Chemical Physics : Pccp. PMID 32598423 DOI: 10.1039/d0cp02216k  0.76
2020 Wnuk SF, Mudgal MM, Nowak I, Robins MJ. Model Substrate/Inactivation Reactions for MoaA and Ribonucleotide Reductases: Loss of Bromo, Chloro, or Tosylate Groups from C2 of 1,5-Dideoxyhomoribofuranoses upon Generation of an α-Oxy Radical at C3. Molecules (Basel, Switzerland). 25. PMID 32486052 DOI: 10.3390/molecules25112539  0.64
2019 Zhao L, Kaiser RI, Lu W, Xu B, Ahmed M, Morozov AN, Mebel AM, Howlader AH, Wnuk SF. Molecular mass growth through ring expansion in polycyclic aromatic hydrocarbons via radical-radical reactions. Nature Communications. 10: 3689. PMID 31417088 DOI: 10.1038/s41467-019-11652-5  0.76
2019 Zhao L, Prendergast M, Kaiser RI, Xu B, Ablikim U, Lu W, Ahmed M, Oleinikov AD, Azyazov VN, Howlader AH, Wnuk SF, Mebel AM. How to add a five-membered ring to polycyclic aromatic hydrocarbons (PAHs) - molecular mass growth of the 2-naphthyl radical (CH) to benzindenes (CH) as a case study. Physical Chemistry Chemical Physics : Pccp. PMID 31322639 DOI: 10.1039/c9cp02930c  0.76
2019 Zhao L, Kaiser RI, Xu B, Ablikim U, Lu W, Ahmed M, Evseev MM, Bashkirov EK, Azyazov VN, Zagidullin MV, Morozov AN, Howlader AH, Wnuk SF, Mebel AM, Joshi D, et al. Gas phase synthesis of [4]-helicene. Nature Communications. 10: 1510. PMID 30944302 DOI: 10.1038/s41467-019-09224-8  0.76
2019 Zhao L, Prendergast MB, Kaiser RI, Xu B, Lu W, Ablikim U, Ahmed M, Oleinikov AD, Azyazov VN, Mebel AM, Howlader AH, Wnuk SF. Reactivity of the Indenyl Radical (C₉H₇) with Acetylene (C₂H₂) and Vinylacetylene (C₄H₄). Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 30938059 DOI: 10.1002/cphc.201900052  0.76
2019 Wen Z, Tuttle PR, Howlader AH, Vasilyeva A, Gonzales L, Tangar A, Lei R, Laverde EE, Liu Y, Miksovska J, Wnuk SF. Fluorescent 5-Pyrimidine and 8-Purine Nucleosides Modified with N-unsubstituted 1,2,3-Triazol-4-yl Moiety. The Journal of Organic Chemistry. PMID 30806513 DOI: 10.1021/acs.joc.8b03135  0.76
2019 Zhao L, Xu B, Ablikim U, Lu W, Ahmed M, Evseev MM, Bashkirov EK, Azyazov VN, Howlader AH, Wnuk SF, Mebel AM, Kaiser RI. Gas Phase Synthesis of Triphenylene (C₁₈H₁₂). Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 30710434 DOI: 10.1002/cphc.201801154  0.76
2018 Wen Z, Peng J, Tuttle PR, Ren Y, Garcia C, Debnath D, Rishi S, Hanson C, Ward S, Kumar A, Liu Y, Zhao W, Glazer PM, Liu Y, Sevilla MD, ... ... Wnuk SF, et al. Electron-Mediated Aminyl and Iminyl Radicals from C5 Azido-Modified Pyrimidine Nucleosides Augment Radiation Damage to Cancer Cells. Organic Letters. PMID 30457873 DOI: 10.1021/acs.orglett.8b03035  0.76
2018 Pulido J, de Cabrera M, Sobczak AJ, Amor-Coarasa A, McGoron AJ, Wnuk SF. 4-N-Alkanoyl and 4-N-alkyl gemcitabine analogues with NOTA chelators for 68-gallium labelling. Bioorganic & Medicinal Chemistry. PMID 30342865 DOI: 10.1016/j.bmc.2018.10.007  0.8
2018 Gonzalez C, de Cabrera M, Wnuk SF. Gemcitabine analogues with 4-N-alkyl chain modified with fluoromethyl ketone group. Nucleosides, Nucleotides & Nucleic Acids. 1-13. PMID 29750577 DOI: 10.1080/15257770.2018.1465186  0.76
2018 Suzol SH, Howlader AH, Wen Z, Ren Y, Laverde EE, Garcia C, Liu Y, Wnuk SF. Pyrimidine Nucleosides with a Reactive (β-Chlorovinyl)sulfone or (β-Keto)sulfone Group at the C5 Position, Their Reactions with Nucleophiles and Electrophiles, and Their Polymerase-Catalyzed Incorporation into DNA. Acs Omega. 3: 4276-4288. PMID 29732453 DOI: 10.1021/acsomega.8b00584  0.76
2018 Zhao L, Kaiser RI, Xu B, Ablikim U, Ahmed M, Zagidullin MV, Azyazov VN, Howlader AH, Wnuk SF, Mebel AM. A VUV Photoionization Study on the Formation of the Simplest Polycyclic Aromatic Hydrocarbon: Naphthalene (C10H8). The Journal of Physical Chemistry Letters. PMID 29717871 DOI: 10.1021/acs.jpclett.8b01020  0.76
2018 Gonzalez C, Sanchez A, Collins J, Lisova K, Lee JT, Michael van Dam R, Alejandro Barbieri M, Ramachandran C, Wnuk SF. The 4-N-acyl and 4-N-alkyl gemcitabine analogues with silicon-fluoride-acceptor: Application toF-Radiolabeling. European Journal of Medicinal Chemistry. 148: 314-324. PMID 29471120 DOI: 10.1016/j.ejmech.2018.02.017  0.76
2017 Mudgal M, Rishi S, Lumpuy DA, Curran KA, Verley KL, Sobczak AJ, Dang TP, Sulimoff N, Kumar A, Sevilla MD, Wnuk SF, Adhikary A. Prehydrated One-Electron Attachment to Azido-Modified Pentafuranoses: Aminyl Radical Formation, Rapid H-Atom Transfer and Subsequent Ring Opening. The Journal of Physical Chemistry. B. PMID 28425714 DOI: 10.1021/acs.jpcb.7b01838  0.8
2017 Wen Z, Suzol SH, Peng J, Liang Y, Snoeck R, Andrei G, Liekens S, Wnuk SF. Antiviral and Cytostatic Evaluation of 5-(1-Halo-2-sulfonylvinyl)- and 5-(2-Furyl)uracil Nucleosides. Archiv Der Pharmazie. PMID 28304114 DOI: 10.1002/ardp.201700023  0.76
2016 He Q, Wang L, Liang Y, Zhang Z, Wnuk SF. Transition-metal-free cross-coupling of aryl halides with arylstannanes. The Journal of Organic Chemistry. PMID 27571510 DOI: 10.1021/acs.joc.6b01648  1
2016 Chbib C, Sobczak AJ, Mudgal M, Gonzalez C, Lumpuy D, Nagaj J, Stokowa-Soltys K, Wnuk SF. S-Ribosylhomocysteine Analogues Modified at the Ribosyl C-4 Position. Journal of Sulphur Chemistry. 37: 307-327. PMID 27516805 DOI: 10.1080/17415993.2015.1137921  0.8
2016 Gonzalez C, Kavoosi S, Sanchez A, Wnuk SF. Reduction of sugar lactones to hemiacetals with lithium triethylborohydride. Carbohydrate Research. 432: 17-22. PMID 27341397 DOI: 10.1016/j.carres.2016.06.002  1
2016 Liang Y, Suzol SH, Wen Z, Artiles AG, Mathivathanan L, Raptis RG, Wnuk SF. Uracil Nucleosides with Reactive Group at C5 Position: 5-(1-Halo-2-sulfonylvinyl)uridine Analogues. Organic Letters. PMID 26933954 DOI: 10.1021/acs.orglett.6b00346  1
2016 Chbib C, Sobczak AJ, Mudgal M, Gonzalez C, Lumpuy D, Nagaj J, Stokowa-Soltys K, Wnuk SF. S-Ribosylhomocysteine analogues modified at the ribosyl C-4 position Journal of Sulfur Chemistry. 1-21. DOI: 10.1080/17415993.2015.1137921  1
2016 Kavoosi S, Rayala R, Walsh B, Barrios M, Gonzalez WG, Miksovska J, Mathivathanan L, Raptis RG, Wnuk SF. Synthesis of 8-(1,2,3-triazol-1-yl)-7-deazapurine nucleosides by azide–alkyne click reactions and direct C[sbnd]H bond functionalization Tetrahedron Letters. 57: 4364-4367. DOI: 10.1016/j.tetlet.2016.08.053  1
2015 Sobczak AJ, Chbib C, Wnuk SF. S-Ribosylhomocysteine analogs containing a [4-thio]ribose ring. Carbohydrate Research. 415: 39-47. PMID 26279525 DOI: 10.1016/j.carres.2015.07.005  1
2015 Zayas J, Annoual M, Das JK, Felty Q, Gonzalez WG, Miksovska J, Sharifai N, Chiba A, Wnuk SF. Strain Promoted Click Chemistry of 2- or 8-Azidopurine and 5-Azidopyrimidine Nucleosides and 8-Azidoadenosine Triphosphate with Cyclooctynes. Application to Living Cell Fluorescent Imaging. Bioconjugate Chemistry. 26: 1519-32. PMID 26086070 DOI: 10.1021/acs.bioconjchem.5b00300  0.44
2015 Liang Y, Wnuk SF. Modification of purine and pyrimidine nucleosides by direct C-H bond activation. Molecules (Basel, Switzerland). 20: 4874-901. PMID 25789821 DOI: 10.3390/molecules20034874  0.6
2015 Zayas J, Annoual M, Das JK, Felty Q, Gonzalez WG, Miksovska J, Sharifai N, Chiba A, Wnuk SF. Strain Promoted Click Chemistry of 2- or 8-Azidopurine and 5-Azidopyrimidine Nucleosides and 8-Azidoadenosine Triphosphate with Cyclooctynes. Application to Living Cell Fluorescent Imaging Bioconjugate Chemistry. 26: 1519-1532. DOI: 10.1021/acs.bioconjchem.5b00300  1
2014 Adhikary A, Kumar A, Rayala R, Hindi RM, Adhikary A, Wnuk SF, Sevilla MD. One-electron oxidation of gemcitabine and analogs: mechanism of formation of C3' and C2' sugar radicals. Journal of the American Chemical Society. 136: 15646-53. PMID 25296262 DOI: 10.1021/ja5083156  0.32
2014 Rayala R, Theard P, Ortiz H, Yao S, Young JD, Balzarini J, Robins MJ, Wnuk SF. Synthesis of purine and 7-deazapurine nucleoside analogues of 6-N-(4-Nitrobenzyl)adenosine; inhibition of nucleoside transport and proliferation of cancer cells. Chemmedchem. 9: 2186-92. PMID 24788480 DOI: 10.1002/cmdc.201402047  1
2014 Liang Y, Gloudeman J, Wnuk SF. Palladium-catalyzed direct arylation of 5-halouracils and 5-halouracil nucleosides with arenes and heteroarenes promoted by TBAF. The Journal of Organic Chemistry. 79: 4094-103. PMID 24724921 DOI: 10.1021/jo500602p  0.6
2014 Pulido J, Sobczak AJ, Balzarini J, Wnuk SF. Synthesis and cytostatic evaluation of 4-N-alkanoyl and 4-N-alkyl gemcitabine analogues. Journal of Medicinal Chemistry. 57: 191-203. PMID 24341356 DOI: 10.1021/jm401586a  0.8
2013 Liang Y, Pitteloud JP, Wnuk SF. Hydrogermylation of 5-ethynyluracil nucleosides: formation of 5-(2-germylvinyl)uracil and 5-(2-germylacetyl)uracil nucleosides. The Journal of Organic Chemistry. 78: 5761-7. PMID 23631719 DOI: 10.1021/jo400590z  1
2013 Adhikary A, Kumar A, Heizer AN, Palmer BJ, Pottiboyina V, Liang Y, Wnuk SF, Sevilla MD. Hydroxyl ion addition to one-electron oxidized thymine: unimolecular interconversion of C5 to C6 OH-adducts. Journal of the American Chemical Society. 135: 3121-35. PMID 23362972 DOI: 10.1021/ja310650n  0.6
2012 Dang TP, Sobczak AJ, Mebel AM, Chatgilialoglu C, Wnuk SF. Investigation of reactions postulated to occur during inhibition of ribonucleotide reductases by 2'-azido-2'-deoxynucleotides. Tetrahedron. 68: 5655-5667. PMID 22711937 DOI: 10.1016/j.tet.2012.04.050  1
2012 Shokar A, Au A, An SH, Tong E, Garza G, Zayas J, Wnuk SF, Land KM. S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine. Bioorganic & Medicinal Chemistry Letters. 22: 4203-5. PMID 22579483 DOI: 10.1016/j.bmcl.2012.03.087  0.44
2011 Malladi VLA, Sobczak AJ, Meyer TM, Pei D, Wnuk SF. Inhibition of LuxS by S-ribosylhomocysteine analogues containing a [4-aza]ribose ring Bioorganic and Medicinal Chemistry. 19: 5507-5519. PMID 21855358 DOI: 10.1016/j.bmc.2011.07.043  1
2011 Malladi VL, Sobczak AJ, Maricic N, Murugapiran SK, Schneper L, Makemson J, Mathee K, Wnuk SF. Substituted lactam and cyclic azahemiacetals modulate Pseudomonas aeruginosa quorum sensing. Bioorganic & Medicinal Chemistry. 19: 5500-6. PMID 21855349 DOI: 10.1016/j.bmc.2011.07.044  1
2010 Pitteloud JP, Zhang ZT, Liang Y, Cabrera L, Wnuk SF. Fluoride-promoted cross-coupling of chloro(mono-, di-, or triphenyl)germanes with aryl halides in "moist" toluene. Multiple transfer of the phenyl group from organogermane substrates and comparison of the coupling efficiencies of chloro(phenyl)germanes with their corresponding stannane and silane counterparts. The Journal of Organic Chemistry. 75: 8199-212. PMID 21067173 DOI: 10.1021/jo101848f  1
2010 Dornbush PJ, Vazquez-Anaya G, Shokar A, Benson S, Rapp M, Wnuk SF, Wrischnik LA, Land KM. AdoHcy hydrolase of Trichomonas vaginalis: studies of the effects of 5'-modified adenosine analogues and related 6-N-cyclopropyl derivatives. Bioorganic & Medicinal Chemistry Letters. 20: 7466-8. PMID 21044841 DOI: 10.1016/j.bmcl.2010.10.014  0.56
2010 Zhang ZT, Pitteloud JP, Cabrera L, Liang Y, Toribio M, Wnuk SF. Arylchlorogermanes/TBAF/"moist" toluene: a promising combination for Pd-catalyzed Germyl-Stille cross-coupling. Organic Letters. 12: 816-9. PMID 20092358 DOI: 10.1021/ol9028918  1
2009 Wnuk SF, Sacasa PR, Restrepo J. Application of germyldesulfonylation reactions to the synthesis of germanium-containing nucleoside analogues. Nucleosides, Nucleotides & Nucleic Acids. 28: 537-49. PMID 20183601 DOI: 10.1080/15257770903054340  1
2009 Sacasa PR, Zayas J, Wnuk SF. Radical-mediated thiodesulfonylation of the vinyl sulfones: Access to (α-fluoro)vinyl sulfides. Tetrahedron Letters. 50: 5424-5427. PMID 20161068 DOI: 10.1016/j.tetlet.2009.07.063  1
2009 Rapp M, Cai X, Xu W, Dolbier WR, Wnuk SF. Reactions of Trimethylsilyl Fluorosulfonyldifluoroacetate with Purine and Pyrimidine Nucleosides. Journal of Fluorine Chemistry. 130: 321-328. PMID 20160856 DOI: 10.1016/j.jfluchem.2008.12.004  0.56
2009 Wnuk SF, Robert J, Sobczak AJ, Meyers BP, Malladi VL, Zhu J, Gopishetty B, Pei D. Inhibition of S-ribosylhomocysteinase (LuxS) by substrate analogues modified at the ribosyl C-3 position. Bioorganic & Medicinal Chemistry. 17: 6699-706. PMID 19682914 DOI: 10.1016/j.bmc.2009.07.057  1
2009 Nair PK, Melnick SJ, Wnuk SF, Rapp M, Escalon E, Ramachandran C. Isolation and characterization of an anticancer catechol compound from Semecarpus anacardium. Journal of Ethnopharmacology. 122: 450-6. PMID 19429311 DOI: 10.1016/j.jep.2009.02.001  0.56
2009 Zipse H, Artin E, Wnuk S, Lohman GJ, Martino D, Griffin RG, Kacprzak S, Kaupp M, Hoffman B, Bennati M, Stubbe J, Lees N. Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 131: 200-11. PMID 19128178 DOI: 10.1021/ja806693s  1
2009 Gopishetty B, Zhu J, Rajan R, Sobczak AJ, Wnuk SF, Bell CE, Pei D. Probing the catalytic mechanism of S-ribosylhomocysteinase (LuxS) with catalytic intermediates and substrate analogues. Journal of the American Chemical Society. 131: 1243-50. PMID 19099445 DOI: 10.1021/ja808206w  1
2008 Wang Z, Pitteloud JP, Montes L, Rapp M, Derane D, Wnuk SF. Vinyl Tris(trimethylsilyl)silanes: Substrates for Hiyama Coupling. Tetrahedron. 64: 5322-5327. PMID 19478830 DOI: 10.1016/j.tet.2008.03.024  1
2008 Wnuk SF, Sacasa PR, Lewandowska E, Andrei D, Cai S, Borchardt RT. Synthesis of 5'-functionalized nucleosides: S-Adenosylhomocysteine analogues with the carbon-5' and sulfur atoms replaced by a vinyl or halovinyl unit. Bioorganic & Medicinal Chemistry. 16: 5424-33. PMID 18457953 DOI: 10.1016/j.bmc.2008.04.017  1
2008 Wnuk SF, Lalama J, Garmendia CA, Robert J, Zhu J, Pei D. S-Ribosylhomocysteine analogues with the carbon-5 and sulfur atoms replaced by a vinyl or (fluoro)vinyl unit. Bioorganic & Medicinal Chemistry. 16: 5090-102. PMID 18375129 DOI: 10.1016/j.bmc.2008.03.028  1
2007 Wnuk SF, Lalama J, Robert J, Garmendia CA. Novel S-ribosylhomocysteine analogues as potential inhibitors of LuxS enzyme. Nucleosides, Nucleotides & Nucleic Acids. 26: 1051-5. PMID 18058535 DOI: 10.1080/15257770701513190  0.48
2007 Robins MJ, Nowak I, Wnuk SF, Hansske F, Madej D. Deoxygenative [1,2]-hydride shift rearrangements in nucleoside and sugar chemistry: analogy with the [1,2]-electron shift in the deoxygenation of ribonucleotides by ribonucleotide reductases. The Journal of Organic Chemistry. 72: 8216-21. PMID 17918996 DOI: 10.1021/jo071102b  1
2006 Xu W, Abboud KA, Ghiviriga I, Dolbier WR, Rapp M, Wnuk SF. An unexpected reaction of trimethylsilyl fluorosulfonyldifluoroacetate (TFDA) with imidazoles. Formation of N-difluoromethylthioureas. Organic Letters. 8: 5549-51. PMID 17107069 DOI: 10.1021/ol062213k  0.56
2006 Andrei D, Wnuk SF. S-adenosylhomocysteine analogues with the carbon-5' and sulfur atoms replaced by a vinyl unit. Organic Letters. 8: 5093-6. PMID 17048851 DOI: 10.1021/ol062026m  1
2006 Wnuk SF, Robins MJ. Ribonucleotide reductase inhibitors as anti-herpes agents. Antiviral Research. 71: 122-6. PMID 16621038 DOI: 10.1016/j.antiviral.2006.03.002  1
2006 Rapp M, Haubrich TA, Perrault J, Mackey ZB, McKerrow JH, Chiang PK, Wnuk SF. Antitrypanosomal activity of 5'-deoxy-5'-(iodomethylene)adenosine and related 6-N-cyclopropyladenosine analogues. Journal of Medicinal Chemistry. 49: 2096-102. PMID 16539398 DOI: 10.1021/jm0511379  1
2006 Andrei D, Wnuk SF. Synthesis of the multisubstituted halogenated olefins via cross-coupling of dihaloalkenes with alkylzinc bromides. The Journal of Organic Chemistry. 71: 405-8. PMID 16388671 DOI: 10.1021/jo051980e  1
2005 Robins MJ, Wnuk SF. Reduction of ribonucleosides to 2'-deoxyribonucleosides. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 1.11. PMID 18428933 DOI: 10.1002/0471142700.nc0111s21  1
2005 Fritscher J, Artin E, Wnuk S, Bar G, Robblee JH, Kacprzak S, Kaupp M, Griffin RG, Bennati M, Stubbe J. Structure of the nitrogen-centered radical formed during inactivation of E. coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine-5'-diphosphate: trapping of the 3'-ketonucleotide. Journal of the American Chemical Society. 127: 7729-38. PMID 15913363 DOI: 10.1021/ja043111x  1
2005 Wang M, Zhang J, Andrei D, Kuczera K, Borchardt RT, Wnuk SF. Are L-adenosine and its derivatives substrates for S-adenosyl-L-homocysteine hydrolase? Journal of Medicinal Chemistry. 48: 3649-53. PMID 15887973 DOI: 10.1021/jm0490484  1
2005 Wang Z, Wnuk SF. Application of vinyl tris(trimethylsilyl)germanes in Pd-catalyzed couplings. The Journal of Organic Chemistry. 70: 3281-4. PMID 15822995 DOI: 10.1021/jo047773g  1
2004 Wnuk SF, Lewandowska E, Sacasa PR, Crain LN, Zhang J, Borchardt RT, De Clercq E. Stereoselective synthesis of sugar-modified enyne analogues of adenosine and uridine. Interaction with S-adenosyl-L-homocysteine hydrolase and antiviral and cytotoxic effects. Journal of Medicinal Chemistry. 47: 5251-7. PMID 15456269 DOI: 10.1021/jm040054+  1
2004 Nair PK, Rodriguez S, Ramachandran R, Alamo A, Melnick SJ, Escalon E, Garcia PI, Wnuk SF, Ramachandran C. Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. International Immunopharmacology. 4: 1645-59. PMID 15454117 DOI: 10.1016/j.intimp.2004.07.024  0.48
2004 Wnuk SF, Garcia PI, Wang Z. Radical-mediated silyl- and germyldesulfonylation of vinyl and (alpha-fluoro)vinyl sulfones: application of tris(trimethylsilyl)silanes and tris(trimethylsilyl)germanes in Pd-catalyzed couplings. Organic Letters. 6: 2047-9. PMID 15176815 DOI: 10.1021/ol049312n  1
2004 Wnuk SF, Lewandowska E, Companioni DR, Garcia PI, Secrist JA. Synthesis and cytotoxicity of 9-(2-deoxy-2-alkyldithio-beta-D-arabinofuranosyl)purine nucleosides which are stable precursors to potential mechanistic probes of ribonucleotide reductases. Organic & Biomolecular Chemistry. 2: 120-6. PMID 14737670 DOI: 10.1039/b311504f  1
2003 Wnuk SF, Sacasa PR, Crain LN, Lewandowska E, Zhang J, Borchardt RT. Stereocontrolled synthesis of diene and enyne sugar-modified nucleosides and their interaction with S-adenosyl-L-homocysteine hydrolase. Nucleosides, Nucleotides & Nucleic Acids. 22: 783-5. PMID 14565278 DOI: 10.1081/NCN-120022634  1
2003 Lewandowska E, Lalama J, Yuan CS, Wnuk SF. Open-chain carbocyclic analogs of adenosine with dihalovinyl unit as potential inhibitors of S-adenosyl-L-homocysteine hydrolase. Nucleosides, Nucleotides & Nucleic Acids. 22: 1747-55. PMID 14533879 DOI: 10.1081/NCN-120023270  0.52
2002 Wnuk SF, Companioni DR, Neschadimenko V, Robins MJ. The beta-fluorine effect. Electronic versus steric effects in radical deoxygenations of fluorine-containing pentofuranose nucleosides. The Journal of Organic Chemistry. 67: 8794-7. PMID 12467391 DOI: 10.1021/jo020428b  1
2002 Merryman C, Weinstein E, Wnuk SF, Bartel DP. A bifunctional tRNA for in vitro selection Chemistry and Biology. 9: 741-746. PMID 12079786 DOI: 10.1016/S1074-5521(02)00161-8  1
2002 Wnuk SF, Ro BO, Valdez CA, Lewandowska E, Valdez NX, Sacasa PR, Yin D, Zhang J, Borchardt RT, De Clercq E. Sugar-modified conjugated diene analogues of adenosine and uridine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects. Journal of Medicinal Chemistry. 45: 2651-8. PMID 12036374 DOI: 10.1021/jm020064f  1
2002 Wnuk SF, Bergolla LA, Garcia PI. Studies toward the synthesis of alpha-fluorinated phosphonates via tin-mediated cleavage of alpha-fluoro-alpha-(pyrimidin-2-ylsulfonyl)alkylphosphonates. Intramolecular cyclization of the alpha-phosphonyl radicals. The Journal of Organic Chemistry. 67: 3065-71. PMID 11975568 DOI: 10.1021/jo0111560  0.48
2002 Wnuk SF, Chowdhury SM, Garcia PI, Robins MJ. Stereodefined synthesis of O3'-labeled uracil nucleosides. 3'-[(17)O]-2'-Azido-2'-deoxyuridine 5'-diphosphate as a probe for the mechanism of inactivation of ribonucleotide reductases. The Journal of Organic Chemistry. 67: 1816-9. PMID 11895397 DOI: 10.1021/jo010899i  1
2001 Wnuk SF, Valdez CA, Valdez NX. Rhodium(I)-catalyzed regio- and stereoselective chloroesterification of furanose-derived terminal alkynes with ethyl chloroformate Journal of Carbohydrate Chemistry. 20: 71-79. DOI: 10.1081/CAR-100102544  1
2000 Yang X, Yin D, Wnuk SF, Robins MJ, Borchardt RT. Mechanisms of inactivation of human S-adenosylhomocysteine hydrolase by 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosines. Biochemistry. 39: 15234-41. PMID 11106503 DOI: 10.1021/bi0015055  1
2000 Wnuk SF, Valdez CA, Khan J, Moutinho P, Robins MJ, Yang X, Borchardt RT, Balzarini J, De Clercq E. Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects. Journal of Medicinal Chemistry. 43: 1180-6. PMID 10737751 DOI: 10.1021/jm990486y  1
2000 Wnuk SF, Rios JM, Khan J, Hsu YL. Stannyl radical-mediated cleavage of π-deficient heterocyclic sulfones. Synthesis of α-fluoro esters Journal of Organic Chemistry. 65: 4169-4174. DOI: 10.1021/jo000342n  1
1999 Giziewicz J, Wnuk SF, Robins MJ. Nucleic Acid Related Compounds. 107. Efficient Nitration of Uracil Base and Nucleoside Derivatives(1). The Journal of Organic Chemistry. 64: 2149-2151. PMID 11674318 DOI: 10.1021/jo9822939  1
1999 Robins MJ, Guo Z, Samano MC, Wnuk SF. Biomimetic simulation of free radical-initiated cascade reactions postulated to occur at the active site of ribonucleotide reductases Journal of the American Chemical Society. 121: X-1432. DOI: 10.1021/ja983449p  1
1999 Guo Z, Samano MC, Krzykawski JW, Wnuk SF, Ewing GJ, Robins MJ. Biomimetic modeling of the abstraction of H3' by ribonucleotide reductases. 1,5-Hydrogen atom transfer of H3 to aminyl and oxyl, but not thlyl, free radicals in homoribofuranose derivatives Tetrahedron. 55: 5705-5718. DOI: 10.1016/S0040-4020(99)00238-0  1
1999 Wnuk SF, Yuan CS, Borchardt RT, Robins MJ. Design and biological evaluation of new mechanism-based inhibitors of S- adenosyl-L-homocysteine hydrolase Nucleosides and Nucleotides. 18: 595-596.  1
1998 Robins MJ, Lewandowska E, Wnuk SF. Nucleic Acid Related Compounds. 105. Synthesis of 2',3'-Didehydro-2',3'-dideoxynucleosides from Ribonucleoside Cyclic 2',3'-(Sulfates or Phosphates) or 2',3'-Dimesylates via Reductive Elimination with Sodium Naphthalenide(1). The Journal of Organic Chemistry. 63: 7375-7381. PMID 11672386  0.64
1998 Robins MJ, Wnuk SF, Yang X, Yuan CS, Borchardt RT, Balzarini J, De Clercq E. Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine). Journal of Medicinal Chemistry. 41: 3857-64. PMID 9748360 DOI: 10.1021/jm980163m  1
1998 Wnuk SF, Yuan CS, Borchardt RT, Robins MJ. Synthesis of homologated halovinyl derivatives from aristeromycin and their inhibition of human placental S-adenosyl-L-homocysteine hydrolase. Nucleosides & Nucleotides. 17: 99-113. PMID 9708344 DOI: 10.1080/07328319808005161  1
1998 Wnuk SF, Mao Y, Yuan CS, Borchardt RT, Andrei G, Balzarini J, De Clercq E, Robins MJ. Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its "hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosine. Journal of Medicinal Chemistry. 41: 3078-83. PMID 9685247 DOI: 10.1021/jm9801410  1
1998 Yuan CS, Wnuk SF, Robins MJ, Borchardt RT. A novel mechanism-based inhibitor (6'-bromo-5', 6'-didehydro-6'-deoxy-6'-fluorohomoadenosine) that covalently modifies human placental S-adenosylhomocysteine hydrolase. The Journal of Biological Chemistry. 273: 18191-7. PMID 9660780 DOI: 10.1074/jbc.273.29.18191  1
1998 Robins MJ, Lewandowska E, Wnuk SF. Nucleic acid related compounds. 105. Synthesis of 2',3'-didehydro- 2',3'-dideoxynucleosides from ribonucleoside cyclic 2',3'-(Sulfates or phosphates) or 2',3'-dimesylates via reductive elimination with sodium naphthalenide Journal of Organic Chemistry. 63: 7375-7381. DOI: 10.1021/jo981013m  1
1998 Robins MJ, Sarker S, Wnuk SF. What are the practical limits for detection of minor nucleoside reaction products with HPLC (UV detection), 1H NMR, and TLC (UV detection)? Nucleosides and Nucleotides. 17: 785-790.  1
1998 Robins MJ, Neschadimenko V, Ro BO, Yuan CS, Borchardt RT, Wnuk SF. Nucleic Acid Related Compounds. 101. S-Adenosyl-L-homocysteine Hydrolase Does Not Hydrate (5′-Fluoro)vinyl or (6′-Halo)homovinyl Analogues Derived from 3′-Deoxyadenosine or 3′-(Chloro or Fluoro)-3′-deoxyadenosine Journal of Organic Chemistry. 63: 1205-1211.  1
1997 Huang H, Yuan CS, Wnuk SF, Robins MJ, Borchardt RT. The mechanism of inactivation of human placental S-adenosylhomocysteine hydrolase by (E)-4',5'-didehydro-5'-methoxyadenosine and adenosine 5'-carboxaldehyde oxime. Archives of Biochemistry and Biophysics. 343: 109-17. PMID 9210652 DOI: 10.1006/abbi.1997.0159  1
1997 Wnuk SF, Yuan CS, Borchardt RT, Balzarini J, De Clercq E, Robins MJ. Anticancer and antiviral effects and inactivation of S-adenosyl-L-homocysteine hydrolase with 5'-carboxaldehydes and oximes synthesized from adenosine and sugar-modified analogues. Journal of Medicinal Chemistry. 40: 1608-18. PMID 9171871 DOI: 10.1021/jm960828p  1
1997 Robins MJ, Guo Z, Wnuk SF. Elimination of chlorine (radical) or tosylate (anion) from C2' of nucleoside C3' free radicals as model reactions postulated to occur at the active site of ribonucleotide reductases Journal of the American Chemical Society. 119: 3637-3638. DOI: 10.1021/ja970171c  1
1997 Lewandowska E, Neschadimenko V, Wnuk SF, Robins MJ. Efficient removal of sugar O-tosyl groups and heterocycle halogens from purine nucleosides with sodium naphthalenide Tetrahedron. 53: 6295-6302. DOI: 10.1016/S0040-4020(97)00313-X  1
1997 Robins MJ, Sarker S, Samano V, Wnuk SF. Nucleic acid related compounds. 94. Remarkably high stereoselective reductions of 2'- and 3'-ketonucleoside derivatives to give arabino, ribo, and xylofuranosyl nucleosides with hydrogen isotopes at C2' and C3' Tetrahedron. 53: 447-456. DOI: 10.1016/S0040-4020(96)01035-6  1
1997 Robins MJ, Zou R, Hansske F, Wnuk SF. Synthesis of sugar-modified 2,6-diaminopurine and guanine nucleosides from guanosine via transformations of 2-aminoadenosine and enzymatic deamination with adenosine deaminase Canadian Journal of Chemistry. 75: 762-767.  1
1996 Wnuk SF, Liu S, Yuan CS, Borchardt RT, Robins MJ. Inactivation of S-adenosyl-L-homocysteine hydrolase by amide and ester derivatives of adenosine-5'-carboxylic acid. Journal of Medicinal Chemistry. 39: 4162-6. PMID 8863793 DOI: 10.1021/jm960313y  1
1996 Robins MJ, Zou R, Guo Z, Wnuk SF. Nucleic acid related compounds. 93. A solution for the historic problem of regioselective sugar-base coupling to produce 9-glycosylguanines or 7-glycosylguanines Journal of Organic Chemistry. 61: 9207-9212. DOI: 10.1021/jo9617023  1
1996 Robins MJ, Guo Z, Samano MC, Wnuk SF. Biomimetic modeling of the decomposition of 2'-chloro-2'-deoxynucleotides by ribonucleotide reductases to give 3(2H)-furanones which can effect mechanism-based inactivation by Michael-type alkylation Journal of the American Chemical Society. 118: 11317-11318. DOI: 10.1021/ja962118e  1
1996 Robins MJ, Wnuk SF, Hernández-Thirring AE, Samano MC. Nucleic acid related compounds. 91. Biomimetic reactions are in harmony with loss of 2'-substituents as free radicals (not anions) during mechanism-based inactivation of ribonucleotide reductases. Differential interactions of azide, halogen, and alkylthio groups with tributylstannane and triphenylsilane Journal of the American Chemical Society. 118: 11341-11348. DOI: 10.1021/ja962117m  1
1996 Yuan CS, Liu S, Wnuk SF, Robins MJ, Borchardt RT. Design and synthesis of S-adenosylhomocysteine hydrolase inhibitors as broad-spectrum antiviral agents Advances in Antiviral Drug Design. 2: 41-88. DOI: 10.1016/S1075-8593(96)80103-1  1
1994 Wenska G, Skalski B, Paszyc S, Wnuk S, Adamiak RW. Fluorescent nucleoside derivatives: Luminescence study of 4-dimethylaminopyridinium chloride derived from guanosine. Journal of Fluorescence. 4: 283-6. PMID 24233599 DOI: 10.1007/BF01881440  1
1994 Yuan CS, Liu S, Wnuk SF, Robins MJ, Borchardt RT. Mechanism of inactivation of S-adenosylhomocysteine hydrolase by (E)-5',6'-didehydro-6'-deoxy-6'-halohomoadenosines. Biochemistry. 33: 3758-65. PMID 8142376  0.64
1994 Wnuk SF, Yuan CS, Borchardt RT, Balzarini J, De Clercq E, Robins MJ. Nucleic acid related compounds. 84. Synthesis of 6'-(E and Z)-halohomovinyl derivatives of adenosine, inactivation of S-adenosyl-L-homocysteine hydrolase, and correlation of anticancer and antiviral potencies with enzyme inhibition. Journal of Medicinal Chemistry. 37: 3579-87. PMID 7932585  0.64
1994 Yuan CS, Wnuk SF, Liu S, Robins MJ, Borchardt RT. (E)-5',6'-didehydro-6'-deoxy-6'-fluorohomoadenosine: a substrate that measures the hydrolytic activity of S-adenosylhomocysteine hydrolase. Biochemistry. 33: 12305-11. PMID 7918452  0.64
1993 Liu S, Wnuk SF, Yuan C, Robins MJ, Borchardt RT. Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase. Journal of Medicinal Chemistry. 36: 883-7. PMID 8464042  0.64
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