Steven Clegg - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Microbiology Biology, Biochemistry

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Clegg S, Murphy CN. Epidemiology and Virulence of Klebsiella pneumoniae. Microbiology Spectrum. 4. PMID 26999397 DOI: 10.1128/Microbiolspec.Uti-0005-2012  0.6
2013 Stahlhut SG, Chattopadhyay S, Kisiela DI, Hvidtfeldt K, Clegg S, Struve C, Sokurenko EV, Krogfelt KA. Structural and population characterization of MrkD, the adhesive subunit of type 3 fimbriae. Journal of Bacteriology. 195: 5602-13. PMID 24123820 DOI: 10.1128/Jb.00753-13  0.45
2013 Sterzenbach T, Nguyen KT, Nuccio SP, Winter MG, Vakulskas CA, Clegg S, Romeo T, Bäumler AJ. A novel CsrA titration mechanism regulates fimbrial gene expression in Salmonella typhimurium. The Embo Journal. 32: 2872-83. PMID 24056837 DOI: 10.1038/Emboj.2013.206  0.468
2013 Zeiner SA, Dwyer BE, Clegg S. FimY does not interfere with FimZ-FimW interaction during type 1 fimbria production by Salmonella enterica serovar Typhimurium. Infection and Immunity. 81: 4453-60. PMID 24042120 DOI: 10.1128/Iai.00795-13  0.475
2013 Childers BM, Van Laar TA, You T, Clegg S, Leung KP. MrkD1P from Klebsiella pneumoniae strain IA565 allows for coexistence with Pseudomonas aeruginosa and protection from protease-mediated biofilm detachment. Infection and Immunity. 81: 4112-20. PMID 23980108 DOI: 10.1128/Iai.00521-13  0.454
2013 Murphy CN, Mortensen MS, Krogfelt KA, Clegg S. Role of Klebsiella pneumoniae type 1 and type 3 fimbriae in colonizing silicone tubes implanted into the bladders of mice as a model of catheter-associated urinary tract infections. Infection and Immunity. 81: 3009-17. PMID 23753626 DOI: 10.1128/Iai.00348-13  0.629
2013 Kisiela DI, Chattopadhyay S, Tchesnokova V, Paul S, Weissman SJ, Medenica I, Clegg S, Sokurenko EV. Evolutionary analysis points to divergent physiological roles of type 1 fimbriae in Salmonella and Escherichia coli. Mbio. 4. PMID 23462115 DOI: 10.1128/Mbio.00625-12  0.44
2012 Rêgo AT, Johnson JG, Gelbel S, Enguita FJ, Clegg S, Waksman G. Crystal structure of the MrkD1P receptor binding domain of Klebsiella pneumoniae and identification of the human collagen V binding interface. Molecular Microbiology. 86: 882-93. PMID 22988966 DOI: 10.1111/Mmi.12023  0.34
2012 Murphy CN, Clegg S. Klebsiella pneumoniae and type 3 fimbriae: nosocomial infection, regulation and biofilm formation. Future Microbiology. 7: 991-1002. PMID 22913357 DOI: 10.2217/Fmb.12.74  0.65
2012 Zeiner SA, Dwyer BE, Clegg S. FimA, FimF, and FimH are necessary for assembly of type 1 fimbriae on Salmonella enterica serovar Typhimurium. Infection and Immunity. 80: 3289-96. PMID 22778099 DOI: 10.1128/Iai.00331-12  0.501
2012 Kisiela DI, Chattopadhyay S, Libby SJ, Karlinsey JE, Fang FC, Tchesnokova V, Kramer JJ, Beskhlebnaya V, Samadpour M, Grzymajlo K, Ugorski M, Lankau EW, Mackie RI, Clegg S, Sokurenko EV. Evolution of Salmonella enterica virulence via point mutations in the fimbrial adhesin. Plos Pathogens. 8: e1002733. PMID 22685400 DOI: 10.1371/Journal.Ppat.1002733  0.42
2011 Dwyer BE, Newton KL, Kisiela D, Sokurenko EV, Clegg S. Single nucleotide polypmorphisms of fimH associated with adherence and biofilm formation by serovars of Salmonella enterica. Microbiology (Reading, England). 157: 3162-71. PMID 21852351 DOI: 10.1099/Mic.0.051425-0  0.445
2011 Johnson JG, Murphy CN, Sippy J, Johnson TJ, Clegg S. Type 3 fimbriae and biofilm formation are regulated by the transcriptional regulators MrkHI in Klebsiella pneumoniae. Journal of Bacteriology. 193: 3453-60. PMID 21571997 DOI: 10.1128/Jb.00286-11  0.696
2011 Clegg S, Wilson J, Johnson J. More than one way to control hair growth: regulatory mechanisms in enterobacteria that affect fimbriae assembled by the chaperone/usher pathway. Journal of Bacteriology. 193: 2081-8. PMID 21398554 DOI: 10.1128/Jb.00071-11  0.441
2010 Johnson JG, Clegg S. Role of MrkJ, a phosphodiesterase, in type 3 fimbrial expression and biofilm formation in Klebsiella pneumoniae. Journal of Bacteriology. 192: 3944-50. PMID 20511505 DOI: 10.1128/Jb.00304-10  0.553
2009 Torrelles JB, DesJardin LE, MacNeil J, Kaufman TM, Kutzbach B, Knaup R, McCarthy TR, Gurcha SS, Besra GS, Clegg S, Schlesinger LS. Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces the cell wall lipoarabinomannan and lipomannan content and increases the rate of bacterial-induced human macrophage cell death. Glycobiology. 19: 743-55. PMID 19318518 DOI: 10.1093/Glycob/Cwp042  0.712
2008 Rosen DA, Pinkner JS, Jones JM, Walker JN, Clegg S, Hultgren SJ. Utilization of an intracellular bacterial community pathway in Klebsiella pneumoniae urinary tract infection and the effects of FimK on type 1 pilus expression. Infection and Immunity. 76: 3337-45. PMID 18411285 DOI: 10.1128/Iai.00090-08  0.508
2007 Nuccio SP, Chessa D, Weening EH, Raffatellu M, Clegg S, Bäumler AJ. SIMPLE approach for isolating mutants expressing fimbriae. Applied and Environmental Microbiology. 73: 4455-62. PMID 17526787 DOI: 10.1128/Aem.00148-07  0.469
2007 Lau HY, Clegg S, Moore TA. Identification of Klebsiella pneumoniae genes uniquely expressed in a strain virulent using a murine model of bacterial pneumonia. Microbial Pathogenesis. 42: 148-55. PMID 17369011 DOI: 10.1016/J.Micpath.2007.01.001  0.473
2007 Mehling JS, Lavender H, Clegg S. A Dam methylation mutant of Klebsiella pneumoniae is partially attenuated. Fems Microbiology Letters. 268: 187-93. PMID 17328745 DOI: 10.1111/J.1574-6968.2006.00581.X  0.451
2006 Boddicker JD, Anderson RA, Jagnow J, Clegg S. Signature-tagged mutagenesis of Klebsiella pneumoniae to identify genes that influence biofilm formation on extracellular matrix material. Infection and Immunity. 74: 4590-7. PMID 16861646 DOI: 10.1128/Iai.00129-06  0.475
2005 McCarthy TR, Torrelles JB, MacFarlane AS, Katawczik M, Kutzbach B, Desjardin LE, Clegg S, Goldberg JB, Schlesinger LS. Overexpression of Mycobacterium tuberculosis manB, a phosphomannomutase that increases phosphatidylinositol mannoside biosynthesis in Mycobacterium smegmatis and mycobacterial association with human macrophages. Molecular Microbiology. 58: 774-90. PMID 16238626 DOI: 10.1111/J.1365-2958.2005.04862.X  0.716
2005 Lavender H, Jagnow JJ, Clegg S. Klebsiella pneumoniae type 3 fimbria-mediated immunity to infection in the murine model of respiratory disease. International Journal of Medical Microbiology : Ijmm. 295: 153-9. PMID 16047414 DOI: 10.1016/J.Ijmm.2005.04.001  0.401
2005 Esteves CL, Jones BD, Clegg S. Biofilm formation by Salmonella enterica serovar Typhimurium and Escherichia coli on epithelial cells following mixed inoculations. Infection and Immunity. 73: 5198-203. PMID 16041039 DOI: 10.1128/Iai.73.8.5198-5203.2005  0.385
2004 Lavender HF, Jagnow JR, Clegg S. Biofilm formation in vitro and virulence in vivo of mutants of Klebsiella pneumoniae. Infection and Immunity. 72: 4888-90. PMID 15271955 DOI: 10.1128/Iai.72.8.4888-4890.2004  0.419
2003 Jagnow J, Clegg S. Klebsiella pneumoniae MrkD-mediated biofilm formation on extracellular matrix- and collagen-coated surfaces. Microbiology (Reading, England). 149: 2397-405. PMID 12949165 DOI: 10.1099/Mic.0.26434-0  0.367
2002 Boddicker JD, Ledeboer NA, Jagnow J, Jones BD, Clegg S. Differential binding to and biofilm formation on, HEp-2 cells by Salmonella enterica serovar Typhimurium is dependent upon allelic variation in the fimH gene of the fim gene cluster. Molecular Microbiology. 45: 1255-65. PMID 12207694 DOI: 10.1046/J.1365-2958.2002.03121.X  0.494
2002 Yeh KS, Tinker JK, Clegg S. FimZ binds the Salmonella typhimurium fimA promoter region and may regulate its own expression with FimY. Microbiology and Immunology. 46: 1-10. PMID 11911183 DOI: 10.1111/J.1348-0421.2002.Tb02670.X  0.736
2002 Clegg S, Hughes KT. FimZ is a molecular link between sticking and swimming in Salmonella enterica serovar Typhimurium. Journal of Bacteriology. 184: 1209-13. PMID 11807085 DOI: 10.1128/Jb.184.4.1209-1213.2002  0.451
2001 Langstraat J, Bohse M, Clegg S. Type 3 fimbrial shaft (MrkA) of Klebsiella pneumoniae, but not the fimbrial adhesin (MrkD), facilitates biofilm formation. Infection and Immunity. 69: 5805-12. PMID 11500458 DOI: 10.1128/Iai.69.9.5805-5812.2001  0.528
2001 Tinker JK, Clegg S. Control of FimY translation and type 1 fimbrial production by the arginine tRNA encoded by fimU in Salmonella enterica serovar Typhimurium. Molecular Microbiology. 40: 757-68. PMID 11359580 DOI: 10.1046/J.1365-2958.2001.02430.X  0.766
2001 Tinker JK, Hancox LS, Clegg S. FimW is a negative regulator affecting type 1 fimbrial expression in Salmonella enterica serovar typhimurium. Journal of Bacteriology. 183: 435-42. PMID 11133935 DOI: 10.1128/Jb.183.2.435-442.2001  0.776
2000 Wilson RL, Elthon J, Clegg S, Jones BD. Salmonella enterica serovars gallinarum and pullorum expressing Salmonella enterica serovar typhimurium type 1 fimbriae exhibit increased invasiveness for mammalian cells. Infection and Immunity. 68: 4782-5. PMID 10899888 DOI: 10.1128/Iai.68.8.4782-4785.2000  0.443
2000 Tinker JK, Clegg S. Characterization of FimY as a coactivator of type 1 fimbrial expression in Salmonella enterica serovar Typhimurium. Infection and Immunity. 68: 3305-13. PMID 10816478 DOI: 10.1128/Iai.68.6.3305-3313.2000  0.768
1999 Sebghati TA, Clegg S. Construction and Characterization of Mutations within theKlebsiella mrkD1P Gene That Affect Binding to Collagen Type V Infection and Immunity. 67: 1672-1676. DOI: 10.1128/Iai.67.4.1672-1676.1999  0.441
1998 Sebghati TA, Korhonen TK, Hornick DB, Clegg S. Characterization of the type 3 fimbrial adhesins of Klebsiella strains. Infection and Immunity. 66: 2887-94. PMID 9596764 DOI: 10.1128/Iai.66.6.2887-2894.1998  0.478
1998 Hancox LS, Yeh KS, Clegg S. Construction and characterization of type 1 non-fimbriate and non-adhesive mutants of Salmonella typhimurium. Fems Immunology and Medical Microbiology. 19: 289-96. PMID 9537754 DOI: 10.1111/J.1574-695X.1997.Tb01099.X  0.507
1996 Clegg S, Hancox LS, Yeh KS. Salmonella typhimurium fimbrial phase variation and FimA expression. Journal of Bacteriology. 178: 542-5. PMID 8550478 DOI: 10.1128/Jb.178.2.542-545.1996  0.307
1995 Hornick DB, Thommandru J, Smits W, Clegg S. Adherence properties of an mrkD-negative mutant of Klebsiella pneumoniae. Infection and Immunity. 63: 2026-32. PMID 7729917 DOI: 10.1128/IAI.63.5.2026-2032.1995  0.358
1995 Yeh KS, Hancox LS, Clegg S. Construction and characterization of a fimZ mutant of Salmonella typhimurium. Journal of Bacteriology. 177: 6861-5. PMID 7592479 DOI: 10.1128/Jb.177.23.6861-6865.1995  0.543
1994 Schurtz TA, Hornick DB, Korhonen TK, Clegg S. The type 3 fimbrial adhesin gene (mrkD) of Klebsiella species is not conserved among all fimbriate strains. Infection and Immunity. 62: 4186-91. PMID 7927674 DOI: 10.1128/Iai.62.10.4186-4191.1994  0.507
1994 Swenson DL, Kim KJ, Six EW, Clegg S. The gene fimU affects expression of Salmonella typhimurium type 1 fimbriae and is related to the Escherichia coli tRNA gene argU. Molecular & General Genetics : Mgg. 244: 216-8. PMID 7914347 DOI: 10.1007/Bf00283525  0.5
1994 Madison B, Ofek I, Clegg S, Abraham SN. Type 1 fimbrial shafts of Escherichia coli and Klebsiella pneumoniae influence sugar-binding specificities of their FimH adhesins Infection and Immunity. 62: 843-848. PMID 7906676 DOI: 10.1128/Iai.62.3.843-848.1994  0.348
1993 Kukkonen M, Raunio T, Virkola R, Lähteenmäki K, Mäkelä PH, Klemm P, Clegg S, Korhonen TK. Basement membrane carbohydrate as a target for bacterial adhesion: binding of type I fimbriae of Salmonella enterica and Escherichia coli to laminin. Molecular Microbiology. 7: 229-37. PMID 8095317 DOI: 10.1111/J.1365-2958.1993.Tb01114.X  0.478
1992 Swenson DL, Clegg S. Identification of ancillary fim genes affecting fimA expression in Salmonella typhimurium Journal of Bacteriology. 174: 7697-7704. PMID 1360005 DOI: 10.1128/Jb.174.23.7697-7704.1992  0.442
1992 Tarkkanen AM, Allen BL, Williams PH, Kauppi M, Haahtela K, Siitonen A, Orskov I, Orskov F, Clegg S, Korhonen TK. Fimbriation, capsulation, and iron-scavenging systems of Klebsiella strains associated with human urinary tract infection. Infection and Immunity. 60: 1187-92. PMID 1347287 DOI: 10.1128/Iai.60.3.1187-1192.1992  0.439
1992 Hornick DB, Allen BL, Horn MA, Clegg S. Adherence to respiratory epithelia by recombinant Escherichia coli expressing Klebsiella pneumoniae type 3 fimbrial gene products. Infection and Immunity. 60: 1577-88. PMID 1312518 DOI: 10.1128/Iai.60.4.1577-1588.1992  0.457
1991 Swenson DL, Clegg S, Old DC. The frequency of fim genes among Salmonella serovars. Microbial Pathogenesis. 10: 487-92. PMID 1686630 DOI: 10.1016/0882-4010(91)90115-Q  0.487
1991 Hornick DB, Allen BL, Horn MA, Clegg S. Fimbrial types among respiratory isolates belonging to the family Enterobacteriaceae. Journal of Clinical Microbiology. 29: 1795-800. PMID 1685495 DOI: 10.1128/Jcm.29.9.1795-1800.1991  0.443
1991 Allen BL, Gerlach GF, Clegg S. Nucleotide sequence and functions of mrk determinants necessary for expression of type 3 fimbriae in Klebsiella pneumoniae. Journal of Bacteriology. 173: 916-20. PMID 1670938 DOI: 10.1128/Jb.173.2.916-920.1991  0.489
1990 Crichton PB, Yakubu DE, Old DC, Clegg S. Immunological and genetical relatedness of type-1 and type-2 fimbriae in salmonellas of serotypes Gallinarum, Pullorum and Typhimurium. The Journal of Applied Bacteriology. 67: 283-91. PMID 2575611 DOI: 10.1111/J.1365-2672.1989.TB02497.X  0.325
1990 Nichols WA, Clegg S, Brown MR. Characterization of the type 1 fimbrial subunit gene (fimA) of Serratia marcescens. Molecular Microbiology. 4: 2119-26. PMID 1982455 DOI: 10.1111/J.1365-2958.1990.Tb00573.X  0.452
1990 Tarkkanen AM, Allen BL, Westerlund B, Holthöfer H, Kuusela P, Risteli L, Clegg S, Korhonen TK. Type V collagen as the target for type-3 fimbriae, enterobacterial adherence organelles. Molecular Microbiology. 4: 1353-61. PMID 1980713 DOI: 10.1111/J.1365-2958.1990.Tb00714.X  0.469
1989 Gerlach GF, Clegg S, Allen BL. Identification and characterization of the genes encoding the type 3 and type 1 fimbrial adhesins of Klebsiella pneumoniae. Journal of Bacteriology. 171: 1262-70. PMID 2563996 DOI: 10.1128/Jb.171.3.1262-1270.1989  0.484
1989 Gerlach GF, Clegg S, Ness NJ, Swenson DL, Allen BL, Nichols WA. Expression of type 1 fimbriae and mannose-sensitive hemagglutinin by recombinant plasmids. Infection and Immunity. 57: 764-70. PMID 2563717 DOI: 10.1128/Iai.57.3.764-770.1989  0.515
1989 Gerlach GF, Allen BL, Clegg S. Type 3 fimbriae among enterobacteria and the ability of spermidine to inhibit MR/K hemagglutination. Infection and Immunity. 57: 219-24. PMID 2562835 DOI: 10.1128/Iai.57.1.219-224.1989  0.43
1988 Gerlach GF, Allen BL, Clegg S. Molecular characterization of the type 3 (MR/K) fimbriae of Klebsiella pneumoniae. Journal of Bacteriology. 170: 3547-53. PMID 2900237 DOI: 10.1128/Jb.170.8.3547-3553.1988  0.393
1988 Gerlach GF, Clegg S. Characterization of two genes encoding antigenically distinct type-1 fimbriae of Klebsiella pneumoniae. Gene. 64: 231-40. PMID 2456966 DOI: 10.1016/0378-1119(88)90338-1  0.442
1988 Gerlach G, Clegg S, Nichols WA. Characterization of the genes encoding urease activity ofKlebsiella pneumoniae Fems Microbiology Letters. 50: 131-135. DOI: 10.1111/J.1574-6968.1988.Tb02925.X  0.465
1988 Gerlach G, Clegg S. Cloning and characterization of the gene cluster encoding type 3 (MR/K) fimbriae ofKlebsiella pneumoniae Fems Microbiology Letters. 49: 377-383. DOI: 10.1111/J.1574-6968.1988.Tb02761.X  0.506
1987 Purcell BK, Pruckler J, Clegg S. Nucleotide sequences of the genes encoding type 1 fimbrial subunits of Klebsiella pneumoniae and Salmonella typhimurium. Journal of Bacteriology. 169: 5831-4. PMID 2890624 DOI: 10.1128/Jb.169.12.5831-5834.1987  0.36
1987 Clegg S, Purcell BK, Pruckler J. Characterization of genes encoding type 1 fimbriae of Klebsiella pneumoniae, Salmonella typhimurium, and Serratia marcescens. Infection and Immunity. 55: 281-7. PMID 2879791 DOI: 10.1128/Iai.55.2.281-287.1987  0.512
1985 Clegg S, Pruckler J, Purcell BK. Complementation analyses of recombinant plasmids encoding type 1 fimbriae of members of the family Enterobacteriaceae. Infection and Immunity. 50: 338-40. PMID 2864314 DOI: 10.1128/Iai.50.1.338-340.1985  0.462
1985 Hull S, Clegg S, Sanborg Eden C, Hull R. Multiple forms of genes in pyelonephritogenic Escherichia coli encoding adhesins binding globoseries glycolipid receptors. Infection and Immunity. 47: 80-3. PMID 2856916 DOI: 10.1128/IAI.47.1.80-83.1985  0.345
1985 Clegg S, Hull S, Hull R, Pruckler J. Construction and comparison of recombinant plasmids encoding type 1 fimbriae of members of the family Enterobacteriaceae. Infection and Immunity. 48: 275-9. PMID 2580786 DOI: 10.1128/IAI.48.2.275-279.1985  0.396
1985 Clegg S, Allen BL. Molecular cloning and expression of an extracellular nuclease of Serratia marcescens in Escherichia coli Fems Microbiology Letters. 27: 257-262. DOI: 10.1111/J.1574-6968.1985.Tb00678.X  0.464
1984 Clegg S, Pierce JK. Organization of genes responsible for the production of mannose-resistant fimbriae of a uropathogenic Escherichia coli isolate. Infection and Immunity. 42: 900-6. PMID 6139340 DOI: 10.1128/IAI.42.3.900-906.1983  0.323
1983 Purcell BK, Clegg S. Construction and expression of recombinant plasmids encoding type 1 fimbriae of a urinary Klebsiella pneumoniae isolate. Infection and Immunity. 39: 1122-7. PMID 6132874 DOI: 10.1128/IAI.39.3.1122-1127.1983  0.407
1983 Clegg S. Cloning of genes determining the production of mannose-resistant fimbriae in a uropathogenic strain of Escherichia coli belonging to serogroup O6. Infection and Immunity. 38: 739-44. PMID 6128310 DOI: 10.1128/IAI.38.2.739-744.1982  0.333
1982 Evans DG, Evans DJ, Clegg S. Detection of enterotoxigenic Escherichia coli colonization factor antigen I in stool specimens by an enzyme-linked immunosorbent assay. Journal of Clinical Microbiology. 12: 738-43. PMID 7031075 DOI: 10.1128/Jcm.12.6.738-743.1980  0.353
1982 Clegg S, Evans DJ, Evans DG. Antigenic heterogeneity of haemagglutination type VI fimbriae produced by Escherichia coli isolated from patients with bacteremia. Journal of Clinical Microbiology. 16: 174-80. PMID 6179963 DOI: 10.1128/Jcm.16.1.174-180.1982  0.398
1979 Evans DG, Evans DJ, Clegg S, Pauley JA. Purification and characterization of the CFA/I antigen of enterotoxigenic Escherichia coli. Infection and Immunity. 25: 738-48. PMID 39896 DOI: 10.1128/Iai.25.2.738-748.1979  0.36
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