Barbara L. Shacklett - Publications

Affiliations: 
Microbiology University of California, Davis, Davis, CA 
Area:
Immunology, Virology Biology, Microbiology Biology, Cell Biology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 SenGupta D, Brinson C, DeJesus E, Mills A, Shalit P, Guo S, Cai Y, Wallin JJ, Zhang L, Humeniuk R, Begley R, Geleziunas R, Mellors J, Wrin T, Jones N, ... ... Shacklett BL, et al. The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy. Science Translational Medicine. 13. PMID 34162752 DOI: 10.1126/scitranslmed.abg3071  0.72
2020 Shacklett BL, Ferre AL, Kiniry BE. Defining T Cell Tissue Residency in Humans: Implications for HIV Pathogenesis and Vaccine Design. Current Hiv/Aids Reports. PMID 32052270 DOI: 10.1007/S11904-020-00481-7  0.72
2019 Shacklett BL, Ferre AL, Kiniry BE. Tissue issues: mucosal T-cell responses in HIV-1 infection. Current Opinion in Hiv and Aids. 14: 100-107. PMID 30601239 DOI: 10.1097/Coh.0000000000000530  0.72
2018 Hughes SM, Ferre AL, Yandura SE, Shetler C, Baker CAR, Calienes F, Levy CN, Astronomo RD, Shu Z, Lentz GM, Fialkow M, Kirby AC, McElrath MJ, Sinclair E, Rohan LC, ... ... Shacklett BL, et al. Cryopreservation of human mucosal tissues. Plos One. 13: e0200653. PMID 30059507 DOI: 10.1371/Journal.Pone.0200653  0.72
2018 Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29352005 DOI: 10.4049/Jimmunol.1701532  0.68
2017 Kiniry BE, Li S, Ganesh A, Hunt PW, Somsouk M, Skinner PJ, Deeks SG, Shacklett BL. Detection of HIV-1-specific gastrointestinal tissue resident CD8(+) T-cells in chronic infection. Mucosal Immunology. PMID 29139476 DOI: 10.1038/Mi.2017.96  0.68
2016 Kiniry BE, Ganesh A, Critchfield JW, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. Predominance of weakly cytotoxic, T-bet(Low)Eomes(Neg) CD8(+) T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunology. PMID 27827375 DOI: 10.1038/Mi.2016.100  0.68
2016 Hughes SM, Shu Z, Levy CN, Ferre AL, Hartig H, Fang C, Lentz G, Fialkow M, Kirby AC, Adams Waldorf KM, Veazey RS, Germann A, von Briesen H, McElrath MJ, Dezzutti CS, ... ... Shacklett BL, et al. Cryopreservation of Human Mucosal Leukocytes. Plos One. 11: e0156293. PMID 27232996 DOI: 10.1371/Journal.Pone.0156293  0.72
2016 Ganesh A, Lemongello D, Lee E, Peterson J, McLaughlin B, Ferre AL, Gillespie G, Fuchs D, Deeks SG, Hunt PW, Price RW, Spudich S, Shacklett BL. Immune Activation and HIV-Specific CD8+ T-cells in Cerebrospinal Fluid of HIV Controllers and Non-Controllers. Aids Research and Human Retroviruses. PMID 27019338 DOI: 10.1089/Aid.2015.0313  0.72
2015 Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC. Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. Plos One. 10: e0129769. PMID 26177352 DOI: 10.1371/Journal.Pone.0129769  0.72
2014 Peterson J, Gisslen M, Zetterberg H, Fuchs D, Shacklett BL, Hagberg L, Yiannoutsos CT, Spudich SS, Price RW. Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection. Plos One. 9: e116081. PMID 25541953 DOI: 10.1371/Journal.Pone.0116081  0.72
2014 Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, et al. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. Plos Pathogens. 10: e1004078. PMID 24831517 DOI: 10.1371/Journal.Ppat.1004078  0.72
2014 Shanmugasundaram U, Critchfield JW, Pannell J, Perry J, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 71: 95-108. PMID 24313954 DOI: 10.1111/Aji.12182  0.72
2013 Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, ... ... Shacklett BL, et al. Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. Plos Pathogens. 9: e1003691. PMID 24130489 DOI: 10.1371/Journal.Ppat.1003691  0.72
2013 Hunt PW, Shulman NS, Hayes TL, Dahl V, Somsouk M, Funderburg NT, McLaughlin B, Landay AL, Adeyemi O, Gilman LE, Clagett B, Rodriguez B, Martin JN, Schacker TW, Shacklett BL, et al. The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial. Blood. 121: 4635-46. PMID 23589670 DOI: 10.1182/Blood-2012-06-436345  0.72
2013 Hayes TL, Asmuth DM, Critchfield JW, Knight TH, McLaughlin BE, Yotter T, McConnell DH, Garcia JC, Pollard RB, Shacklett BL. Impact of highly active antiretroviral therapy initiation on CD4(+) T-cell repopulation in duodenal and rectal mucosa. Aids (London, England). 27: 867-77. PMID 23262500 DOI: 10.1097/Qad.0B013E32835D85B4  0.72
2013 Leeansyah E, Ganesh A, Quigley MF, Sönnerborg A, Andersson J, Hunt PW, Somsouk M, Deeks SG, Martin JN, Moll M, Shacklett BL, Sandberg JK. Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection. Blood. 121: 1124-35. PMID 23243281 DOI: 10.1182/Blood-2012-07-445429  0.72
2013 Dahl V, Peterson J, Spudich S, Lee E, Shacklett BL, Price RW, Palmer S. Single-copy assay quantification of HIV-1 RNA in paired cerebrospinal fluid and plasma samples from elite controllers. Aids (London, England). 27: 1145-9. PMID 23211774 DOI: 10.1097/Qad.0B013E32835Cf235  0.72
2013 Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL. Short communication: HIV+ viremic slow progressors maintain low regulatory T cell numbers in rectal mucosa but exhibit high T cell activation. Aids Research and Human Retroviruses. 29: 172-7. PMID 22998457 DOI: 10.1089/Aid.2012.0268  0.72
2012 Schunter M, Chu H, Hayes TL, McConnell D, Crawford SS, Luciw PA, Bengmark S, Asmuth DM, Brown J, Bevins CL, Shacklett BL, Critchfield JW. Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infection. Bmc Complementary and Alternative Medicine. 12: 84. PMID 22747752 DOI: 10.1186/1472-6882-12-84  0.72
2011 Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL. Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers. Journal of Virology. 85: 11422-34. PMID 21880771 DOI: 10.1128/Jvi.05608-11  0.72
2011 Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG. A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. The Journal of Infectious Diseases. 203: 960-8. PMID 21402547 DOI: 10.1093/Infdis/Jiq138  0.72
2011 Shacklett BL, Ferre AL. Mucosal immunity in HIV controllers: the right place at the right time. Current Opinion in Hiv and Aids. 6: 202-7. PMID 21399497 DOI: 10.1097/Coh.0B013E3283453E2B  0.72
2011 Shacklett BL, Greenblatt RM. Immune responses to HIV in the female reproductive tract, immunologic parallels with the gastrointestinal tract, and research implications. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 65: 230-41. PMID 21223420 DOI: 10.1111/J.1600-0897.2010.00948.X  0.72
2010 Ferre AL, Hunt PW, McConnell DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses. Journal of Virology. 84: 11020-9. PMID 20719952 DOI: 10.1128/Jvi.00980-10  0.72
2010 Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers. Journal of Virology. 84: 10354-65. PMID 20668079 DOI: 10.1128/Jvi.00803-10  0.72
2010 North TW, Higgins J, Deere JD, Hayes TL, Villalobos A, Adamson L, Shacklett BL, Schinazi RF, Luciw PA. Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS. Journal of Virology. 84: 2913-22. PMID 20032180 DOI: 10.1128/Jvi.02356-09  0.72
2009 Dubie RA, Maksaereekul S, Shacklett BL, Lemongello D, Cole KS, Villinger F, Blozis SA, Luciw PA, Sparger EE. Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251. Virology. 386: 109-21. PMID 19193388 DOI: 10.1016/J.Virol.2009.01.007  0.72
2009 Ferre AL, Hunt PW, Critchfield JW, Young DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control. Blood. 113: 3978-89. PMID 19109229 DOI: 10.1182/Blood-2008-10-182709  0.72
2009 Shacklett BL, Critchfield JW, Ferre AL, Hayes TL. Mucosal T-cell responses to HIV: responding at the front lines. Journal of Internal Medicine. 265: 58-66. PMID 19093960 DOI: 10.1111/J.1365-2796.2008.02042.X  0.72
2008 Critchfield JW, Young DH, Hayes TL, Braun JV, Garcia JC, Pollard RB, Shacklett BL. Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status. Plos One. 3: e3577. PMID 18974782 DOI: 10.1371/Journal.Pone.0003577  0.72
2008 Emu B, Sinclair E, Hatano H, Ferre A, Shacklett B, Martin JN, McCune JM, Deeks SG. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control Journal of Virology. 82: 5398-5407. PMID 18353945 DOI: 10.1128/Jvi.02176-07  0.72
2008 Sparger EE, Dubie RA, Shacklett BL, Cole KS, Chang WL, Luciw PA. Vaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine. Virology. 374: 261-72. PMID 18261756 DOI: 10.1016/J.Virol.2008.01.020  0.72
2006 Guadalupe M, Sankaran S, George MD, Reay E, Verhoeven D, Shacklett BL, Flamm J, Wegelin J, Prindiville T, Dandekar S. Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection. Journal of Virology. 80: 8236-47. PMID 16873279 DOI: 10.1128/Jvi.00120-06  0.72
2005 Roland ME, Neilands TB, Krone MR, Katz MH, Franses K, Grant RM, Busch MP, Hecht FM, Shacklett BL, Kahn JO, Bamberger JD, Coates TJ, Chesney MA, Martin JN. Seroconversion following nonoccupational postexposure prophylaxis against HIV. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 41: 1507-13. PMID 16231265 DOI: 10.1086/497268  0.72
2004 Shacklett BL, Cox CA, Quigley MF, Kreis C, Stollman NH, Jacobson MA, Andersson J, Sandberg JK, Nixon DF. Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 173: 641-8. PMID 15210827 DOI: 10.4049/Jimmunol.173.1.641  0.72
2004 Shacklett BL, Cox CA, Wilkens DT, Karlsson RK, Nilsson A, Nixon DF, Price RW. Increased adhesion molecule and chemokine receptor expression on CD8 + T cells trafficking to cerebrospinal fluid in HIV-1 infection Journal of Infectious Diseases. 189: 2202-2212. PMID 15181567 DOI: 10.1086/421244  0.72
2004 Karlsson RK, Jennes W, Page-Shafer K, Nixon DF, Shacklett BL. Poorly soluble peptides can mimic authentic ELISPOT responses. Journal of Immunological Methods. 285: 89-92. PMID 14871537 DOI: 10.1016/J.Jim.2003.11.013  0.72
2004 Chandwani R, Jordan KA, Shacklett BL, Papasavvas E, Montaner LJ, Rosenberg MG, Nixon DF, Sandberg JK. Limited magnitude and breadth in the HLA-A2-restricted CD8 T-Cell response to Nef in children with vertically acquired HIV-1 infection. Scandinavian Journal of Immunology. 59: 109-14. PMID 14723629 DOI: 10.1111/J.0300-9475.2004.01365.X  0.72
2003 Shacklett BL, Yang O, Hausner MA, Elliott J, Hultin L, Price C, Fuerst M, Matud J, Hultin P, Cox C, Ibarrondo J, Wong JT, Nixon DF, Anton PA, Jamieson BD. Optimization of methods to assess human mucosal T-cell responses to HIV infection. Journal of Immunological Methods. 279: 17-31. PMID 12969544 DOI: 10.1016/S0022-1759(03)00255-2  0.72
2003 Shacklett BL, Cox CA, Sandberg JK, Stollman NH, Jacobson MA, Nixon DF. Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection. Journal of Virology. 77: 5621-31. PMID 12719554 DOI: 10.1128/Jvi.77.10.5621-5631.2003  0.72
2002 Shacklett BL, Shaw KE, Adamson LA, Wilkens DT, Cox CA, Montefiori DC, Gardner MB, Sonigo P, Luciw PA. Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251. Journal of Virology. 76: 11365-78. PMID 12388697 DOI: 10.1128/Jvi.76.22.11365-11378.2002  0.72
2002 Jennes W, Kestens L, Nixon DF, Shacklett BL. Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15--the Amplispot assay. Journal of Immunological Methods. 270: 99-108. PMID 12379342 DOI: 10.1016/S0022-1759(02)00275-2  0.72
2000 Shacklett BL, Cu-Uvin S, Beadle TJ, Pace CA, Fast NM, Donahue SM, Caliendo AM, Flanigan TP, Carpenter CC, Nixon DF. Quantification of HIV-1-specific T-cell responses at the mucosal cervicovaginal surface. Aids (London, England). 14: 1911-5. PMID 10997394 DOI: 10.1097/00002030-200009080-00005  0.72
2000 Shacklett BL, Weber CJ, Shaw KES, Keddie EM, Gardner MB, Sonigo P, Luciw PA. The intracytoplasmic domain of the Env transmembrane protein is a locus for attenuation of simian immunodeficiency virus SIVmac in rhesus macaques Journal of Virology. 74: 5836-5844. PMID 10846063 DOI: 10.1128/Jvi.74.13.5836-5844.2000  0.72
1998 Luciw PA, Shaw KES, Shacklett BL, Marthas ML. Importance of the intracytoplasmic domain of the simian immunodeficiency virus (SIV) envelope glycoprotein for pathogenesis Virology. 252: 9-16. PMID 9875311 DOI: 10.1006/Viro.1998.9467  0.72
1994 Shacklett BL, Luciw PA. Analysis of the VIF Gene of Feline Immunodeficiency Virus Virology. 204: 860-867. PMID 7941360 DOI: 10.1006/Viro.1994.1609  0.72
1992 Phillips TR, Lamont C, Konings DA, Shacklett BL, Hamson CA, Luciw PA, Elder JH. Identification of the Rev transactivation and Rev-responsive elements of feline immunodeficiency virus. Journal of Virology. 66: 5464-71. PMID 1323707 DOI: 10.1128/Jvi.66.9.5464-5471.1992  0.72
1992 Sparger EE, Shacklett BL, Renshaw-Gegg L, Barry PA, Pedersen NC, Elder JH, Luciw PA. Regulation of gene expression directed by the long terminal repeat of the feline immunodeficiency virus Virology. 187: 165-177. PMID 1310554 DOI: 10.1016/0042-6822(92)90305-9  0.72
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