Barbara L. Shacklett - Publications

Affiliations: 
Microbiology University of California, Davis, Davis, CA 
Area:
Immunology, Virology Biology, Microbiology Biology, Cell Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Omidvari N, Jones T, Price PM, Ferre AL, Lu J, Abdelhafez YG, Sen F, Cohen SH, Schmiedehausen K, Badawi RD, Shacklett BL, Wilson I, Cherry SR. First-in-human immunoPET imaging of COVID-19 convalescent patients using dynamic total-body PET and a CD8-targeted minibody. Science Advances. 9: eadh7968. PMID 37824612 DOI: 10.1126/sciadv.adh7968  0.766
2023 Sandberg JK, Leeansyah E, Eller MA, Shacklett BL, Paquin-Proulx D. The Emerging Role of MAIT Cell Responses in Viral Infections. Journal of Immunology (Baltimore, Md. : 1950). 211: 511-517. PMID 37549397 DOI: 10.4049/jimmunol.2300147  0.393
2023 Silhol R, Nordsletten A, Maheu-Giroux M, Elmes J, Staunton R, Owen B, Shacklett B, McGowan I, Feliciano KG, van der Straten A, Eller LA, Robb M, Marrazzo J, Dimitrov D, Boily MC. The Association Between Heterosexual anal Intercourse and HIV Acquisition in Three Prospective Cohorts of Women. Aids and Behavior. PMID 37392271 DOI: 10.1007/s10461-023-04115-y  0.324
2023 Omidvari N, Jones T, Price PM, Ferre AL, Lu J, Abdelhafez YG, Sen F, Cohen SH, Schmiedehausen K, Badawi RD, Shacklett BL, Wilson I, Cherry SR. First-in-human immunoPET imaging of COVID-19 convalescent patients using dynamic total-body PET and a CD8-targeted minibody. Medrxiv : the Preprint Server For Health Sciences. PMID 36993568 DOI: 10.1101/2023.03.14.23287121  0.756
2023 Shacklett BL, Buggert M, Dias J. Editorial: CD8+ T-cells in HIV/SIV infection, prophylaxis, and therapy. Frontiers in Immunology. 14: 1159452. PMID 36895565 DOI: 10.3389/fimmu.2023.1159452  0.557
2021 Munusamy Ponnan S, Thiruvengadam K, Tellapragada C, Ambikan AT, Narayanan A, Kathirvel S, Mathayan M, Shankar J, Rajaraman A, Afshan Amanulla M, Dinesha TR, Poongulali S, Saravanan S, Murugavel KG, Swaminathan S, ... ... Shacklett B, et al. Deciphering the Role of Mucosal Immune Responses and the Cervicovaginal Microbiome in Resistance to HIV Infection in HIV-Exposed Seronegative (HESN) Women. Microbiology Spectrum. 9: e0047021. PMID 34704803 DOI: 10.1128/Spectrum.00470-21  0.607
2021 SenGupta D, Brinson C, DeJesus E, Mills A, Shalit P, Guo S, Cai Y, Wallin JJ, Zhang L, Humeniuk R, Begley R, Geleziunas R, Mellors J, Wrin T, Jones N, ... ... Shacklett BL, et al. The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy. Science Translational Medicine. 13. PMID 34162752 DOI: 10.1126/scitranslmed.abg3071  0.785
2021 Gisslen M, Keating SM, Spudich S, Arechiga V, Stephenson S, Zetterberg H, Di Germanio C, Blennow K, Fuchs D, Hagberg L, Norris PJ, Peterson J, Shacklett BL, Yiannoutsos CT, Price RW. Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression. Plos One. 16: e0250987. PMID 33983973 DOI: 10.1371/journal.pone.0250987  0.418
2021 Wu G, Zuck P, Goh SL, Milush JM, Vohra P, Wong JK, Somsouk M, Yukl SA, Shacklett BL, Chomont N, Haase AT, Hatano H, Schacker TW, Deeks SG, Hazuda DJ, et al. Gag p24 is a Marker of HIV Expression in Tissues and Correlates with Immune Response. The Journal of Infectious Diseases. PMID 33693750 DOI: 10.1093/infdis/jiab121  0.56
2021 O'Neil TR, Hu K, Truong NR, Arshad S, Shacklett BL, Cunningham AL, Nasr N. The Role of Tissue Resident Memory CD4 T Cells in Herpes Simplex Viral and HIV Infection. Viruses. 13. PMID 33668777 DOI: 10.3390/v13030359  0.444
2020 Seidman D, Cavrois M, Hilton JF, Roan NR, Averbach S, Takeda M, Chang E, Raman N, Greenblatt R, Shacklett BL, Smith-McCune K. Reproductive tract immune cells from pregnant women or those using depot medroxyprogesterone acetate show no excess susceptibility to HIV-1: results of an ex vivo fusion assay. Contraception. PMID 33007299 DOI: 10.1016/j.contraception.2020.09.003  0.445
2020 Elmes J, Silhol R, Hess KL, Gedge LM, Nordsletten A, Staunton R, Anton P, Shacklett B, McGowan I, Dang Q, Adimora AA, Dimitrov DT, Aral S, Handanagic S, Paz-Bailey G, et al. Receptive anal sex contributes substantially to heterosexually-acquired HIV infections among at-risk women in Twenty US Cities: results from a modelling analysis. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e13263. PMID 32384198 DOI: 10.1111/Aji.13263  0.508
2020 Shanmugasundaram U, Critchfield JW, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. Parallel studies of mucosal immunity in the reproductive and gastrointestinal mucosae of HIV-infected women. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e13246. PMID 32301548 DOI: 10.1111/Aji.13246  0.648
2020 Shacklett BL, Ferre AL, Kiniry BE. Defining T Cell Tissue Residency in Humans: Implications for HIV Pathogenesis and Vaccine Design. Current Hiv/Aids Reports. PMID 32052270 DOI: 10.1007/S11904-020-00481-7  0.804
2020 Lal KG, Kim D, Costanzo MC, Creegan M, Leeansyah E, Dias J, Paquin-Proulx D, Eller LA, Schuetz A, Phuang-Ngern Y, Krebs SJ, Slike BM, Kibuuka H, Maganga L, Nitayaphan S, ... ... Shacklett BL, et al. Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection. Nature Communications. 11: 272. PMID 31937782 DOI: 10.1038/S41467-019-13975-9  0.577
2019 Stannah J, Silhol R, Elmes J, Owen B, Shacklett BL, Anton P, McGowan I, van der Straten A, Dimitrov D, Baggaley RF, Boily MC. Increases in HIV Incidence Following Receptive Anal Intercourse Among Women: A Systematic Review and Meta-analysis. Aids and Behavior. PMID 31486008 DOI: 10.1007/S10461-019-02651-0  0.41
2019 Cavrois M, Hilton JF, Roan NR, Takeda M, Seidman D, Averbach S, Chang E, Raman N, Greenblatt R, Shacklett BL, Smith-McCune K. Effects of the levonorgestrel-containing intrauterine device, copper intrauterine device, and levonorgestrel-containing oral contraceptive on susceptibility of immune cells from cervix, endometrium and blood to HIV-1 fusion measured ex vivo. Plos One. 14: e0221181. PMID 31437197 DOI: 10.1371/Journal.Pone.0221181  0.578
2019 Shacklett BL. Mucosal Immunity in HIV/SIV Infection: T Cells, B Cells and Beyond. Current Immunology Reviews. 15: 63-75. PMID 31327960 DOI: 10.2174/1573395514666180528081204  0.57
2019 Shacklett BL, Blanco J, Hightow-Weidman L, Mgodi N, Alcami J, Buchbinder S, Chirenje M, Dabee S, Diallo M, Dumchev K, Herrera C, Levy ME, Martin-Gayo E, Makoah NA, Mitchell KM, et al. HIVR4P 2018: From Research to Impact. Aids Research and Human Retroviruses. PMID 31007035 DOI: 10.1089/Aid.2019.0074  0.454
2019 Owen BN, Baggaley RF, Elmes J, Harvey A, Shubber Z, Butler AR, Silhol R, Anton P, Shacklett B, van der Straten A, Boily MC. What Proportion of Female Sex Workers Practise anal Intercourse and How Frequently? A Systematic Review and Meta-analysis. Aids and Behavior. PMID 30953304 DOI: 10.1007/S10461-019-02477-W  0.366
2019 Cattin A, Salinas TRW, Gosselin A, Planas D, Shacklett B, Cohen EA, Ghali MP, Routy JP, Ancuta P. HIV-1 is rarely detected in blood and colon myeloid cells during viral-suppressive antiretroviral therapy. Aids (London, England). PMID 30870200 DOI: 10.1097/Qad.0000000000002195  0.543
2019 Shacklett BL, Ferre AL, Kiniry BE. Tissue issues: mucosal T-cell responses in HIV-1 infection. Current Opinion in Hiv and Aids. 14: 100-107. PMID 30601239 DOI: 10.1097/Coh.0000000000000530  0.826
2018 Baggaley RF, Owen BN, Silhol R, Elmes J, Anton P, McGowan I, van der Straten A, Shacklett B, Dang Q, Swann EM, Bolton DL, Boily MC. Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e13039. PMID 30175479 DOI: 10.1111/Aji.13039  0.4
2018 Hughes SM, Ferre AL, Yandura SE, Shetler C, Baker CAR, Calienes F, Levy CN, Astronomo RD, Shu Z, Lentz GM, Fialkow M, Kirby AC, McElrath MJ, Sinclair E, Rohan LC, ... ... Shacklett BL, et al. Cryopreservation of human mucosal tissues. Plos One. 13: e0200653. PMID 30059507 DOI: 10.1371/Journal.Pone.0200653  0.739
2018 Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29352005 DOI: 10.4049/Jimmunol.1701532  0.557
2017 Kiniry BE, Li S, Ganesh A, Hunt PW, Somsouk M, Skinner PJ, Deeks SG, Shacklett BL. Detection of HIV-1-specific gastrointestinal tissue resident CD8(+) T-cells in chronic infection. Mucosal Immunology. PMID 29139476 DOI: 10.1038/Mi.2017.96  0.63
2017 Shacklett BL, Derdeyn CA, Folayan MO, Landovitz R, Anthony C, Behrens AJ, Hope T, Landais E, Leal L, Marrazzo JM, Morris L, Mugo N, Ngure K, Noseda V, Ranasinghe S, et al. HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights. Aids Research and Human Retroviruses. PMID 28649869 DOI: 10.1089/Aid.2017.0125  0.495
2017 Owen BN, Elmes J, Silhol R, Dang Q, McGowan I, Shacklett B, Swann EM, van der Straten A, Baggaley RF, Boily MC. How common and frequent is heterosexual anal intercourse among South Africans? A systematic review and meta-analysis. Journal of the International Aids Society. 19: 1-14. PMID 28364565 DOI: 10.7448/Ias.20.1.21162  0.436
2017 Chang WL, Gonzalez DF, Kieu HT, Castillo LD, Messaoudi I, Shen X, Tomaras GD, Shacklett BL, Barry PA, Sparger EE. Changes in Circulating B Cell Subsets Associated with Aging and Acute SIV Infection in Rhesus Macaques. Plos One. 12: e0170154. PMID 28095513 DOI: 10.1371/Journal.Pone.0170154  0.427
2017 Smith-McCune KK, Hilton JF, Shanmugasundaram U, Critchfield JW, Greenblatt RM, Seidman D, Averbach S, Giudice LC, Shacklett BL. Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility. Mucosal Immunology. PMID 28051087 DOI: 10.1038/Mi.2016.121  0.603
2016 Gosselin A, Salinas TR, Planas D, Wacleche VS, Zhang Y, Fromentin R, Chomont N, Cohen ÉA, Shacklett B, Mehraj V, Ghali MP, Routy JP, Ancuta P. HIV persists in CCR6+CD4+ T-cells from colon and blood during antiretroviral therapy. Aids (London, England). PMID 27835617 DOI: 10.1097/Qad.0000000000001309  0.624
2016 Kiniry BE, Ganesh A, Critchfield JW, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. Predominance of weakly cytotoxic, T-bet(Low)Eomes(Neg) CD8(+) T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunology. PMID 27827375 DOI: 10.1038/Mi.2016.100  0.677
2016 Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice LC, Averbach S, Seidman D, Shacklett BL, Smith-McCune K. Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 76: 137-48. PMID 27401588 DOI: 10.1111/Aji.12535  0.385
2016 Hughes SM, Shu Z, Levy CN, Ferre AL, Hartig H, Fang C, Lentz G, Fialkow M, Kirby AC, Adams Waldorf KM, Veazey RS, Germann A, von Briesen H, McElrath MJ, Dezzutti CS, ... ... Shacklett BL, et al. Cryopreservation of Human Mucosal Leukocytes. Plos One. 11: e0156293. PMID 27232996 DOI: 10.1371/Journal.Pone.0156293  0.785
2016 Deere JD, Chang WL, Castillo LD, Schmidt KA, Kieu HT, Renzette N, Kowalik T, Barthold SW, Shacklett BL, Barry PA, Sparger EE. Utilizing a TLR5-Adjuvanted Cytomegalovirus as a Lentiviral Vaccine in the Nonhuman Primate Model for AIDS. Plos One. 11: e0155629. PMID 27182601 DOI: 10.1371/Journal.Pone.0155629  0.444
2016 Ganesh A, Lemongello D, Lee E, Peterson J, McLaughlin B, Ferre AL, Gillespie G, Fuchs D, Deeks SG, Hunt PW, Price RW, Spudich S, Shacklett BL. Immune Activation and HIV-Specific CD8+ T-cells in Cerebrospinal Fluid of HIV Controllers and Non-Controllers. Aids Research and Human Retroviruses. PMID 27019338 DOI: 10.1089/Aid.2015.0313  0.844
2015 Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC. Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. Plos One. 10: e0129769. PMID 26177352 DOI: 10.1371/Journal.Pone.0129769  0.426
2014 Peterson J, Gisslen M, Zetterberg H, Fuchs D, Shacklett BL, Hagberg L, Yiannoutsos CT, Spudich SS, Price RW. Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection. Plos One. 9: e116081. PMID 25541953 DOI: 10.1371/Journal.Pone.0116081  0.532
2014 Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, et al. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. Plos Pathogens. 10: e1004078. PMID 24831517 DOI: 10.1371/Journal.Ppat.1004078  0.789
2014 Shanmugasundaram U, Critchfield JW, Pannell J, Perry J, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 71: 95-108. PMID 24313954 DOI: 10.1111/Aji.12182  0.507
2014 Shanmugasundaram U, Critchfield J, Pannell J, Perry J, Greene W, Giudice L, Smith-McCune K, Greenblatt R, Shacklett B. Effects of progestin-only contraceptives on the phenotype and function of female reproductive tract CD4+ and CD8+ T cells Bmc Infectious Diseases. 14: 1-1. DOI: 10.1186/1471-2334-14-S3-O21  0.451
2014 Sandberg JK, Dias J, Shacklett B, Leeansyah E. Erratum: Will loss of your mucosa-associated invariant T cells weaken your HAART? (AIDS (2013) 27 (2501-2504)) Aids. 28. DOI: 10.1097/01.Aids.0000440808.25527.F1  0.426
2013 Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, ... ... Shacklett BL, et al. Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. Plos Pathogens. 9: e1003691. PMID 24130489 DOI: 10.1371/Journal.Ppat.1003691  0.813
2013 Sandberg JK, Dias J, Shacklett BL, Leeansyah E. Will loss of your MAITs weaken your HAART [corrected]? Aids (London, England). 27: 2501-4. PMID 23595154 DOI: 10.1097/Qad.0B013E3283620726  0.587
2013 Hunt PW, Shulman NS, Hayes TL, Dahl V, Somsouk M, Funderburg NT, McLaughlin B, Landay AL, Adeyemi O, Gilman LE, Clagett B, Rodriguez B, Martin JN, Schacker TW, Shacklett BL, et al. The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial. Blood. 121: 4635-46. PMID 23589670 DOI: 10.1182/Blood-2012-06-436345  0.613
2013 Hayes TL, Asmuth DM, Critchfield JW, Knight TH, McLaughlin BE, Yotter T, McConnell DH, Garcia JC, Pollard RB, Shacklett BL. Impact of highly active antiretroviral therapy initiation on CD4(+) T-cell repopulation in duodenal and rectal mucosa. Aids (London, England). 27: 867-77. PMID 23262500 DOI: 10.1097/Qad.0B013E32835D85B4  0.498
2013 Leeansyah E, Ganesh A, Quigley MF, Sönnerborg A, Andersson J, Hunt PW, Somsouk M, Deeks SG, Martin JN, Moll M, Shacklett BL, Sandberg JK. Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection. Blood. 121: 1124-35. PMID 23243281 DOI: 10.1182/Blood-2012-07-445429  0.599
2013 Dahl V, Peterson J, Spudich S, Lee E, Shacklett BL, Price RW, Palmer S. Single-copy assay quantification of HIV-1 RNA in paired cerebrospinal fluid and plasma samples from elite controllers. Aids (London, England). 27: 1145-9. PMID 23211774 DOI: 10.1097/Qad.0B013E32835Cf235  0.519
2013 Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL. Short communication: HIV+ viremic slow progressors maintain low regulatory T cell numbers in rectal mucosa but exhibit high T cell activation. Aids Research and Human Retroviruses. 29: 172-7. PMID 22998457 DOI: 10.1089/Aid.2012.0268  0.567
2012 Schunter M, Chu H, Hayes TL, McConnell D, Crawford SS, Luciw PA, Bengmark S, Asmuth DM, Brown J, Bevins CL, Shacklett BL, Critchfield JW. Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infection. Bmc Complementary and Alternative Medicine. 12: 84. PMID 22747752 DOI: 10.1186/1472-6882-12-84  0.525
2012 Presicce P, Shaw JM, Miller CJ, Shacklett BL, Chougnet CA. Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells. Aids (London, England). 26: 263-73. PMID 22095196 DOI: 10.1097/Qad.0B013E32834Ed8Df  0.482
2011 Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL. Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers. Journal of Virology. 85: 11422-34. PMID 21880771 DOI: 10.1128/Jvi.05608-11  0.658
2011 Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG. A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. The Journal of Infectious Diseases. 203: 960-8. PMID 21402547 DOI: 10.1093/Infdis/Jiq138  0.667
2011 Shacklett BL, Ferre AL. Mucosal immunity in HIV controllers: the right place at the right time. Current Opinion in Hiv and Aids. 6: 202-7. PMID 21399497 DOI: 10.1097/Coh.0B013E3283453E2B  0.817
2011 Shacklett BL, Greenblatt RM. Immune responses to HIV in the female reproductive tract, immunologic parallels with the gastrointestinal tract, and research implications. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 65: 230-41. PMID 21223420 DOI: 10.1111/J.1600-0897.2010.00948.X  0.583
2010 Ferre AL, Hunt PW, McConnell DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses. Journal of Virology. 84: 11020-9. PMID 20719952 DOI: 10.1128/Jvi.00980-10  0.839
2010 Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers. Journal of Virology. 84: 10354-65. PMID 20668079 DOI: 10.1128/Jvi.00803-10  0.839
2010 Shacklett BL. Immune responses to HIV and SIV in mucosal tissues: 'location, location, location'. Current Opinion in Hiv and Aids. 5: 128-34. PMID 20543589 DOI: 10.1097/Coh.0B013E328335C178  0.646
2010 Shacklett BL, Anton PA. HIV Infection and Gut Mucosal Immune Function: Updates on Pathogenesis with Implications for Management and Intervention. Current Infectious Disease Reports. 12: 19-27. PMID 20174448 DOI: 10.1007/S11908-009-0072-9  0.66
2010 North TW, Higgins J, Deere JD, Hayes TL, Villalobos A, Adamson L, Shacklett BL, Schinazi RF, Luciw PA. Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS. Journal of Virology. 84: 2913-22. PMID 20032180 DOI: 10.1128/Jvi.02356-09  0.49
2009 Shacklett BL. Cell-mediated immunity to HIV in the female reproductive tract. Journal of Reproductive Immunology. 83: 190-5. PMID 19857902 DOI: 10.1016/J.Jri.2009.07.012  0.597
2009 Dubie RA, Maksaereekul S, Shacklett BL, Lemongello D, Cole KS, Villinger F, Blozis SA, Luciw PA, Sparger EE. Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251. Virology. 386: 109-21. PMID 19193388 DOI: 10.1016/J.Virol.2009.01.007  0.492
2009 Ferre AL, Hunt PW, Critchfield JW, Young DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control. Blood. 113: 3978-89. PMID 19109229 DOI: 10.1182/Blood-2008-10-182709  0.835
2009 Shacklett BL, Critchfield JW, Ferre AL, Hayes TL. Mucosal T-cell responses to HIV: responding at the front lines. Journal of Internal Medicine. 265: 58-66. PMID 19093960 DOI: 10.1111/J.1365-2796.2008.02042.X  0.845
2009 Shacklett BL, Critchfield JW, Lemongello D. Quantifying HIV-1-specific CD8 (+) T-cell responses using ELISPOT and cytokine flow cytometry. Methods in Molecular Biology (Clifton, N.J.). 485: 359-74. PMID 19020837 DOI: 10.1007/978-1-59745-170-3_24  0.617
2009 Shacklett BL, Critchfield JW, Lemongello D. Isolating mucosal lymphocytes from biopsy tissue for cellular immunology assays. Methods in Molecular Biology (Clifton, N.J.). 485: 347-56. PMID 19020836 DOI: 10.1007/978-1-59745-170-3_23  0.487
2008 Shacklett BL. Mucosal immunity to HIV: a review of recent literature. Current Opinion in Hiv and Aids. 3: 541-7. PMID 19373019 DOI: 10.1097/Coh.0B013E32830Ab9Ee  0.501
2008 Critchfield JW, Young DH, Hayes TL, Braun JV, Garcia JC, Pollard RB, Shacklett BL. Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status. Plos One. 3: e3577. PMID 18974782 DOI: 10.1371/Journal.Pone.0003577  0.636
2008 McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Li J, Beckett L, Shacklett BL, Evans TG, Asmuth DM. Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 411-20. PMID 18383309 DOI: 10.1002/Cyto.A.20556  0.364
2008 Emu B, Sinclair E, Hatano H, Ferre A, Shacklett B, Martin JN, McCune JM, Deeks SG. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control Journal of Virology. 82: 5398-5407. PMID 18353945 DOI: 10.1128/Jvi.02176-07  0.825
2008 Sparger EE, Dubie RA, Shacklett BL, Cole KS, Chang WL, Luciw PA. Vaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine. Virology. 374: 261-72. PMID 18261756 DOI: 10.1016/J.Virol.2008.01.020  0.32
2008 Shacklett BL. Can the new humanized mouse model give HIV research a boost. Plos Medicine. 5: e13. PMID 18198940 DOI: 10.1371/Journal.Pmed.0050013  0.492
2007 Critchfield JW, Lemongello D, Walker DH, Garcia JC, Asmuth DM, Pollard RB, Shacklett BL. Multifunctional human immunodeficiency virus (HIV) gag-specific CD8+ T-cell responses in rectal mucosa and peripheral blood mononuclear cells during chronic HIV type 1 infection. Journal of Virology. 81: 5460-71. PMID 17344302 DOI: 10.1128/Jvi.02535-06  0.649
2006 Guadalupe M, Sankaran S, George MD, Reay E, Verhoeven D, Shacklett BL, Flamm J, Wegelin J, Prindiville T, Dandekar S. Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection. Journal of Virology. 80: 8236-47. PMID 16873279 DOI: 10.1128/Jvi.00120-06  0.626
2006 Zuber B, Quigley MF, Critchfield JW, Shacklett BL, Abel K, Miller CJ, Mörner A, Paulie S, Ahlborg N, Sandberg JK. Detection of macaque perforin expression and release by flow cytometry, immunohistochemistry, ELISA, and ELISpot. Journal of Immunological Methods. 312: 45-53. PMID 16647080 DOI: 10.1016/J.Jim.2006.02.018  0.527
2006 Shacklett BL. Understanding the "lucky few": the conundrum of HIV-exposed, seronegative individuals. Current Hiv/Aids Reports. 3: 26-31. PMID 16522256 DOI: 10.1007/S11908-006-0066-9  0.536
2006 Quigley MF, Abel K, Zuber B, Miller CJ, Sandberg JK, Shacklett BL. Perforin expression in the gastrointestinal mucosa is limited to acute simian immunodeficiency virus infection. Journal of Virology. 80: 3083-7. PMID 16501118 DOI: 10.1128/Jvi.80.6.3083-3087.2006  0.443
2005 Roland ME, Neilands TB, Krone MR, Katz MH, Franses K, Grant RM, Busch MP, Hecht FM, Shacklett BL, Kahn JO, Bamberger JD, Coates TJ, Chesney MA, Martin JN. Seroconversion following nonoccupational postexposure prophylaxis against HIV. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 41: 1507-13. PMID 16231265 DOI: 10.1086/497268  0.489
2005 Nixon DF, Deeks SG, Shacklett BL, Karlsson AC. Multidrug-resistant, dual-tropic HIV-1 and rapid progression. Lancet (London, England). 365: 1924-5. PMID 15936414 DOI: 10.1016/S0140-6736(05)66653-6  0.471
2004 Shacklett BL, Cox CA, Quigley MF, Kreis C, Stollman NH, Jacobson MA, Andersson J, Sandberg JK, Nixon DF. Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 173: 641-8. PMID 15210827 DOI: 10.4049/Jimmunol.173.1.641  0.659
2004 Shacklett BL, Cox CA, Wilkens DT, Karlsson RK, Nilsson A, Nixon DF, Price RW. Increased adhesion molecule and chemokine receptor expression on CD8 + T cells trafficking to cerebrospinal fluid in HIV-1 infection Journal of Infectious Diseases. 189: 2202-2212. PMID 15181567 DOI: 10.1086/421244  0.619
2004 Karlsson RK, Jennes W, Page-Shafer K, Nixon DF, Shacklett BL. Poorly soluble peptides can mimic authentic ELISPOT responses. Journal of Immunological Methods. 285: 89-92. PMID 14871537 DOI: 10.1016/J.Jim.2003.11.013  0.419
2004 Chandwani R, Jordan KA, Shacklett BL, Papasavvas E, Montaner LJ, Rosenberg MG, Nixon DF, Sandberg JK. Limited magnitude and breadth in the HLA-A2-restricted CD8 T-Cell response to Nef in children with vertically acquired HIV-1 infection. Scandinavian Journal of Immunology. 59: 109-14. PMID 14723629 DOI: 10.1111/J.0300-9475.2004.01365.X  0.617
2003 Shacklett BL, Yang O, Hausner MA, Elliott J, Hultin L, Price C, Fuerst M, Matud J, Hultin P, Cox C, Ibarrondo J, Wong JT, Nixon DF, Anton PA, Jamieson BD. Optimization of methods to assess human mucosal T-cell responses to HIV infection. Journal of Immunological Methods. 279: 17-31. PMID 12969544 DOI: 10.1016/S0022-1759(03)00255-2  0.608
2003 Shacklett BL, Cox CA, Sandberg JK, Stollman NH, Jacobson MA, Nixon DF. Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection. Journal of Virology. 77: 5621-31. PMID 12719554 DOI: 10.1128/Jvi.77.10.5621-5631.2003  0.638
2002 Shacklett BL, Ling B, Veazey RS, Luckay A, Moretto WJ, Wilkens DT, Hu J, Israel ZR, Nixon DF, Marx PA. Boosting of SIV-specific T cell responses in rhesus macaques that resist repeated intravaginal challenge with SIVmac251. Aids Research and Human Retroviruses. 18: 1081-8. PMID 12396459 DOI: 10.1089/08892220260235434  0.559
2002 Shacklett BL. Beyond 51Cr release: New methods for assessing HIV-1-specific CD8+ T cell responses in peripheral blood and mucosal tissues. Clinical and Experimental Immunology. 130: 172-82. PMID 12390303 DOI: 10.1046/J.1365-2249.2002.01981.X  0.617
2002 Shacklett BL, Shaw KE, Adamson LA, Wilkens DT, Cox CA, Montefiori DC, Gardner MB, Sonigo P, Luciw PA. Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251. Journal of Virology. 76: 11365-78. PMID 12388697 DOI: 10.1128/Jvi.76.22.11365-11378.2002  0.421
2002 Jennes W, Kestens L, Nixon DF, Shacklett BL. Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15--the Amplispot assay. Journal of Immunological Methods. 270: 99-108. PMID 12379342 DOI: 10.1016/S0022-1759(02)00275-2  0.423
2002 Shacklett BL, Means RE, Larsson M, Wilkens DT, Beadle TJ, Merritt MJ, Bhardwaj N, Palumbo PE, Skurnick JH, Louria DB, Nixon DF. Dendritic cell amplification of HIV type 1-specific CD8+ T cell responses in exposed, seronegative heterosexual women. Aids Research and Human Retroviruses. 18: 805-15. PMID 12167272 DOI: 10.1089/08892220260139558  0.634
2002 Skurnick JH, Palumbo P, DeVico A, Shacklett BL, Valentine FT, Merges M, Kamin-Lewis R, Mestecky J, Denny T, Lewis GK, Lloyd J, Praschunus R, Baker A, Nixon DF, Stranford S, et al. Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure. The Journal of Infectious Diseases. 185: 428-38. PMID 11865394 DOI: 10.1086/338830  0.608
2002 Larsson M, Wilkens DT, Fonteneau JF, Beadle TJ, Merritt MJ, Kost RG, Haslett PA, Cu-Uvin S, Bhardwaj N, Nixon DF, Shacklett BL. Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cells. Aids (London, England). 16: 171-80. PMID 11807300 DOI: 10.1097/00002030-200201250-00005  0.579
2001 Tolfvenstam T, Oxenius A, Price DA, Shacklett BL, Spiegel HM, Hedman K, Norbeck O, Levi M, Olsen K, Kantzanou M, Nixon DF, Broliden K, Klenerman P. Direct ex vivo measurement of CD8(+) T-lymphocyte responses to human parvovirus B19. Journal of Virology. 75: 540-3. PMID 11119624 DOI: 10.1128/Jvi.75.1.540-543.2001  0.381
2000 Shacklett BL, Cu-Uvin S, Beadle TJ, Pace CA, Fast NM, Donahue SM, Caliendo AM, Flanigan TP, Carpenter CC, Nixon DF. Quantification of HIV-1-specific T-cell responses at the mucosal cervicovaginal surface. Aids (London, England). 14: 1911-5. PMID 10997394 DOI: 10.1097/00002030-200009080-00005  0.56
2000 Shacklett BL, Beadle TJ, Pacheco PA, Grendell JH, Haslett PA, King AS, Ogg GS, Basuk PM, Nixon DF. Isolation of cytomegalovirus-specific cytotoxic T-lymphocytes from gut-associated lymphoid tissue (GALT) of HIV type 1-infected subjects. Aids Research and Human Retroviruses. 16: 1157-62. PMID 10954891 DOI: 10.1089/088922200415009  0.614
2000 Shacklett BL, Weber CJ, Shaw KES, Keddie EM, Gardner MB, Sonigo P, Luciw PA. The intracytoplasmic domain of the Env transmembrane protein is a locus for attenuation of simian immunodeficiency virus SIVmac in rhesus macaques Journal of Virology. 74: 5836-5844. PMID 10846063 DOI: 10.1128/Jvi.74.13.5836-5844.2000  0.348
2000 Shacklett BL, Beadle TJ, Pacheco PA, Grendell JH, Haslett PA, King AS, Ogg GS, Basuk PM, Nixon DF. Characterization of HIV-1-specific cytotoxic T lymphocytes expressing the mucosal lymphocyte integrin CD103 in rectal and duodenal lymphoid tissue of HIV-1-infected subjects. Virology. 270: 317-27. PMID 10792991 DOI: 10.1006/Viro.2000.0299  0.665
1999 Berlioz-Torrent C, Shacklett BL, Erdtmann L, Delamarre L, Bouchaert I, Sonigo P, Dokhelar MC, Benarous R. Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins. Journal of Virology. 73: 1350-61. PMID 9882340 DOI: 10.1128/Jvi.73.2.1350-1361.1999  0.496
1998 Shacklett BL, Denesvre C, Boson B, Sonigo P. Features of the SIVmac transmembrane glycoprotein cytoplasmic domain that are important for Env functions. Aids Research and Human Retroviruses. 14: 373-83. PMID 9546796 DOI: 10.1089/Aid.1998.14.373  0.379
1998 Sol N, Tréboute C, Gomas E, Ferchal F, Shacklett B, Alizon M. The rhesus macaque CCR3 chemokine receptor is a cell entry cofactor for HIV-2, but not for HIV-1. Virology. 240: 213-20. PMID 9454694 DOI: 10.1006/Viro.1997.8928  0.585
1994 Shacklett BL, Luciw PA. Analysis of the VIF Gene of Feline Immunodeficiency Virus Virology. 204: 860-867. PMID 7941360 DOI: 10.1006/Viro.1994.1609  0.361
1992 Phillips TR, Lamont C, Konings DA, Shacklett BL, Hamson CA, Luciw PA, Elder JH. Identification of the Rev transactivation and Rev-responsive elements of feline immunodeficiency virus. Journal of Virology. 66: 5464-71. PMID 1323707 DOI: 10.1128/Jvi.66.9.5464-5471.1992  0.302
1992 Sparger EE, Shacklett BL, Renshaw-Gegg L, Barry PA, Pedersen NC, Elder JH, Luciw PA. Regulation of gene expression directed by the long terminal repeat of the feline immunodeficiency virus Virology. 187: 165-177. PMID 1310554 DOI: 10.1016/0042-6822(92)90305-9  0.352
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