Year |
Citation |
Score |
2022 |
Tan S, Groaz E, Kalkeri R, Ptak R, Korba BE, Herdewijn P. Reshaping an Acyclic Nucleoside Phosphonate into a Selective Anti-hepatitis B Virus Compound. Journal of Medicinal Chemistry. 65: 9396-9417. PMID 35754374 DOI: 10.1021/acs.jmedchem.2c00667 |
0.448 |
|
2019 |
Akkina R, Barber DL, Bility MT, Bissig KD, Burwitz BJ, Eichelberg K, Endsley JJ, Garcia JV, Hafner R, Karakousis PC, Korba BE, Koshy R, Lambros C, Menne S, Nuermberger EL, et al. Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop. Current Hiv Research. PMID 31870268 DOI: 10.2174/1570162X18666191223114019 |
0.333 |
|
2017 |
Jones M, Cunningham ME, Wing P, DeSilva S, Challa R, Sheri A, Padmanabhan S, Iyer RP, Korba BE, Afdhal N, Foster GR. SB 9200, a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants. Journal of Medical Virology. PMID 28303593 DOI: 10.1002/Jmv.24809 |
0.51 |
|
2015 |
Mohlman MK, Saleh DA, Ezzat S, Abdel-Hamid M, Korba B, Shetty K, Amr S, Loffredo CA. Viral transmission risk factors in an Egyptian population with high hepatitis C prevalence. Bmc Public Health. 15: 1030. PMID 26446713 DOI: 10.1186/S12889-015-2369-Y |
0.418 |
|
2015 |
Korba B, Shetty K, Medvedev A, Viswanathan P, Varghese R, Zhou B, Roy R, Makambi K, Ressom H, Loffredo C. Hepatitis C Virus Genotype 1a Core Gene Nucleotide Patterns Associated with Hepatocellular Carcinoma Risk. The Journal of General Virology. PMID 26296571 DOI: 10.1099/Jgv.0.000219 |
0.402 |
|
2015 |
de Castro S, Fernández-Cureses G, Andrei G, Snoeck R, Sánchez-Murcia PA, Korba B, Gago F, Balzarini J, Camarasa MJ. Conservation of antiviral activity and improved selectivity in PMEO-DAPym upon pyrimidine to triazine scaffold hopping. Antiviral Research. 122: 64-8. PMID 26275802 DOI: 10.1016/J.Antiviral.2015.08.006 |
0.412 |
|
2014 |
Kaufman SS, Green KY, Korba BE. Treatment of norovirus infections: moving antivirals from the bench to the bedside. Antiviral Research. 105: 80-91. PMID 24583027 DOI: 10.1016/J.Antiviral.2014.02.012 |
0.32 |
|
2013 |
Viswanathan P, May J, Uhm S, Yon C, Korba B. RNA binding by human Norovirus 3C-like proteases inhibits protease activity. Virology. 438: 20-7. PMID 23399036 DOI: 10.1016/J.Virol.2013.01.006 |
0.32 |
|
2013 |
Rawal RK, Singh US, Chavre SN, Wang J, Sugiyama M, Hung W, Govindarajan R, Korba B, Tanaka Y, Chu CK. 2'-Fluoro-6'-methylene-carbocyclic adenosine phosphoramidate (FMCAP) prodrug: in vitro anti-HBV activity against the lamivudine-entecavir resistant triple mutant and its mechanism of action. Bioorganic & Medicinal Chemistry Letters. 23: 503-6. PMID 23237841 DOI: 10.1016/J.Bmcl.2012.11.027 |
0.392 |
|
2012 |
Wang J, Singh US, Rawal RK, Sugiyama M, Yoo J, Jha AK, Scroggin M, Huang Z, Murray MG, Govindarajan R, Tanaka Y, Korba B, Chu CK. Corrigendum to “Antiviral activity of novel 2′-fluoro-6′-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutants” [Bioorg. Med. Chem. Lett. 21 (2011) 6328–6331] Bioorganic & Medicinal Chemistry Letters. 22: 2641. DOI: 10.1016/J.Bmcl.2011.10.046 |
0.413 |
|
2011 |
Stachulski AV, Pidathala C, Row EC, Sharma R, Berry NG, Lawrenson AS, Moores SL, Iqbal M, Bentley J, Allman SA, Edwards G, Helm A, Hellier J, Korba BE, Semple JE, et al. Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication. Journal of Medicinal Chemistry. 54: 8670-80. PMID 22059983 DOI: 10.1021/jm201264t |
0.457 |
|
2011 |
Wang J, Singh US, Rawal RK, Sugiyama M, Sugiyama M, Yoo J, Jha AK, Scroggin M, Huang Z, Murray MG, Govindarajan R, Tanaka Y, Korba B, Chu CK. Antiviral activity of novel 2'-fluoro-6'-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutants. Bioorganic & Medicinal Chemistry Letters. 21: 6328-31. PMID 21930377 DOI: 10.1016/J.Bmcl.2011.08.113 |
0.413 |
|
2011 |
Yon C, Viswanathan P, Rossignol JF, Korba B. Mutations in HCV non-structural genes do not contribute to resistance to nitazoxanide in replicon-containing cells. Antiviral Research. 91: 233-40. PMID 21703309 DOI: 10.1016/J.Antiviral.2011.05.017 |
0.431 |
|
2011 |
Gadthula S, Rawal RK, Sharon A, Wu D, Korba B, Chu CK. Synthesis and antiviral activity of cyclopropyl-spirocarbocyclic adenosine, (4R,5S,6R,7R)-4-(6-amino-9H-purin-9-yl)-7-(hydroxymethyl)spiro[2.4]heptane-5,6-diol against hepatitis C virus Bioorganic & Medicinal Chemistry Letters. 21: 3982-3985. PMID 21621997 DOI: 10.1016/J.Bmcl.2011.05.012 |
0.431 |
|
2011 |
Stachulski AV, Pidathala C, Row EC, Sharma R, Berry NG, Iqbal M, Bentley J, Allman SA, Edwards G, Helm A, Hellier J, Korba BE, Semple JE, Rossignol JF. Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication. Journal of Medicinal Chemistry. 54: 4119-32. PMID 21553812 DOI: 10.1021/Jm200153P |
0.514 |
|
2011 |
Montero A, Viswanathan P, Yon C, Korba B. Nitazoxanide is an Indirect Inhibitor of HCV Replication Through Modulation of Cellular Kinase CKI Alpha to Enhance HCV NS5A Hyperphosphorylation Antiviral Research. 90. DOI: 10.1016/J.Antiviral.2011.03.115 |
0.6 |
|
2010 |
Wauchope OR, Tomney MJ, Pepper JL, Korba BE, Seley-Radtke KL. Tricyclic 2'-C-modified nucleosides as potential anti-HCV therapeutics. Organic Letters. 12: 4466-9. PMID 20845910 DOI: 10.1021/Ol101482H |
0.464 |
|
2010 |
Niu C, Bao H, Tolstykh T, Micolochick Steuer HM, Murakami E, Korba B, Furman PA. Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/nucleotide inhibitors. Antiviral Therapy. 15: 401-12. PMID 20516559 DOI: 10.3851/Imp1541 |
0.442 |
|
2010 |
Bader T, Korba B. Simvastatin potentiates the anti-hepatitis B virus activity of FDA-approved nucleoside analogue inhibitors in vitro. Antiviral Research. 86: 241-245. PMID 20211652 DOI: 10.1016/J.Antiviral.2010.02.325 |
0.485 |
|
2010 |
Coughlin JE, Padmanabhan S, Zhang G, Kirk CJ, Govardhan CP, Korba BE, O'Loughlin K, Green CE, Mirsalis J, Morrey JD, Iyer RP. Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugs. Bioorganic & Medicinal Chemistry Letters. 20: 1783-6. PMID 20117930 DOI: 10.1016/J.Antiviral.2010.02.378 |
0.516 |
|
2010 |
Brnakova Z, Chandler KB, Bekesova S, Lenco J, Bebu I, Kosti O, Shetty K, Korba BE, Ressom HW, Varghese RS, Novotny MV, Goldman R. Abstract 5569: N-glycosylation in cultured cells and hepatocellular carcinoma Cancer Research. 70: 5569-5569. DOI: 10.1158/1538-7445.Am10-5569 |
0.403 |
|
2010 |
Tomney M, Korba B, Zimmermann S, Seley-Radtke K. Synthesis of a Series of 2′-Modified Tricyclic Nucleosides as Potential HCV Agents Antiviral Research. 86: A68. DOI: 10.1016/J.Antiviral.2010.02.472 |
0.402 |
|
2009 |
Morrey JD, Korba BE, Beadle JR, Wyles DL, Hostetler KY. Alkoxyalkyl esters of 9-(s)-(3-hydroxy-2-phosphonomethoxypropyl) adenine are potent and selective inhibitors of hepatitis B virus (HBV) replication in vitro and in HBV transgenic mice in vivo. Antimicrobial Agents and Chemotherapy. 53: 2865-70. PMID 19398648 DOI: 10.1128/Aac.00114-09 |
0.518 |
|
2009 |
Wyles DL, Kaihara KA, Korba BE, Schooley RT, Beadle JR, Hostetler KY. The octadecyloxyethyl ester of (S)-9-[3-hydroxy-2-(phosphonomethoxy) propyl]adenine is a potent and selective inhibitor of hepatitis C virus replication in genotype 1A, 1B, and 2A replicons. Antimicrobial Agents and Chemotherapy. 53: 2660-2. PMID 19289518 DOI: 10.1128/Aac.01546-08 |
0.388 |
|
2009 |
Kim HJ, Sharon A, Bal C, Wang J, Allu M, Huang Z, Murray MG, Bassit L, Schinazi RF, Korba B, Chu CK. Synthesis and anti-hepatitis B virus and anti-hepatitis C virus activities of 7-deazaneplanocin A analogues in vitro. Journal of Medicinal Chemistry. 52: 206-13. PMID 19072694 DOI: 10.1021/Jm801418V |
0.533 |
|
2009 |
Korba B, Glenn J, Elazar M, Rossignol J. A Role for Nitazoxanide in Combination with STAT-C Agents for Inhibition of HCV Replication and the Potential for the Prevention of Viral Resistance Antiviral Research. 82. DOI: 10.1016/J.Antiviral.2009.02.022 |
0.451 |
|
2008 |
Korba BE, Elazar M, Lui P, Rossignol JF, Glenn JS. Potential for hepatitis C virus resistance to nitazoxanide or tizoxanide. Antimicrobial Agents and Chemotherapy. 52: 4069-71. PMID 18710916 DOI: 10.1128/Aac.00078-08 |
0.479 |
|
2008 |
Bourne C, Lee S, Venkataiah B, Lee A, Korba B, Finn MG, Zlotnick A. Small-molecule effectors of hepatitis B virus capsid assembly give insight into virus life cycle. Journal of Virology. 82: 10262-70. PMID 18684823 DOI: 10.1128/Jvi.01360-08 |
0.453 |
|
2008 |
Li C, Prichard MN, Korba BE, Drach JC, Zemlicka J. Fluorinated methylenecyclopropane analogues of nucleosides. Synthesis and antiviral activity of (Z)- and (E)-9-{[(2-fluoromethyl-2-hydroxymethyl)-cyclopropylidene]methyl}adenine and -guanine. Bioorganic & Medicinal Chemistry. 16: 2148-55. PMID 18082410 DOI: 10.1016/J.Bmc.2007.11.082 |
0.328 |
|
2008 |
Korba BE, Montero AB, Farrar K, Gaye K, Mukerjee S, Ayers MS, Rossignol JF. Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication. Antiviral Research. 77: 56-63. PMID 17888524 DOI: 10.1016/J.Antiviral.2007.08.005 |
0.721 |
|
2008 |
Werman A, Korba BE, Alkahe B, Finkelshtein D, Bujanover S, Novick D, Vinocour E, Rubinstein M. 54 A soluble form of the LDL receptor inhibits hepatitis B virus replication in vitro Cytokine. 43: 249-249. DOI: 10.1016/J.Cyto.2008.07.095 |
0.499 |
|
2008 |
Johnston B, Vlassov A, Korba B, Farrar K, Mukerjee S, Seyhan A, ILves H, Kaspar R, Leake D, Kazakov S, Ge Q. Optimization of shRNA Features for Targeting Hepatitis C Virus Antiviral Research. 78: A41. DOI: 10.1016/J.Antiviral.2008.01.078 |
0.434 |
|
2007 |
Painter GR, Almond MR, Trost LC, Lampert BM, Neyts J, De Clercq E, Korba BE, Aldern KA, Beadle JR, Hostetler KY. Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl]- adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections. Antimicrobial Agents and Chemotherapy. 51: 3505-9. PMID 17646420 DOI: 10.1128/Aac.01375-07 |
0.448 |
|
2007 |
Vlassov AV, Korba B, Farrar K, Mukerjee S, Seyhan AA, Ilves H, Kaspar RL, Leake D, Kazakov SA, Johnston BH. shRNAs targeting hepatitis C: effects of sequence and structural features, and comparision with siRNA. Oligonucleotides. 17: 223-36. PMID 17638526 DOI: 10.1089/Oli.2006.0069 |
0.441 |
|
2007 |
Zhang P, Zhang N, Korba BE, Hosmane RS. Structure-activity relationship studies on anti-HCV activity of ring-expanded ('fat') nucleobase analogues containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system. Bioorganic & Medicinal Chemistry Letters. 17: 2225-8. PMID 17300935 DOI: 10.1016/J.Bmcl.2007.01.085 |
0.383 |
|
2007 |
Izzo F, Montella M, Orlando AP, Nasti G, Beneduce G, Castello G, Cremona F, Ensor CM, Holtzberg FW, Bomalaski JS, Clark MA, Curley SA, Orlando R, Scordino F, Korba BE. Pegylated arginine deiminase lowers hepatitis C viral titers and inhibits nitric oxide synthesis. Journal of Gastroenterology and Hepatology. 22: 86-91. PMID 17201887 DOI: 10.1111/J.1440-1746.2006.04463.X |
0.484 |
|
2007 |
Choo H, Beadle JR, Kern ER, Prichard MN, Keith KA, Hartline CB, Trahan J, Aldern KA, Korba BE, Hostetler KY. Antiviral activities of novel 5-phosphono-pent-2-en-1-yl nucleosides and their alkoxyalkyl phosphonoesters. Antimicrobial Agents and Chemotherapy. 51: 611-5. PMID 17130297 DOI: 10.1128/Aac.00444-06 |
0.545 |
|
2007 |
Kim H, Sharon A, Korba BE, Chu CK. Synthesis and Anti-HBV Activity of 7-Deaza-Neplanocin A Analogs Antiviral Research. 74. DOI: 10.1016/J.Antiviral.2007.01.088 |
0.435 |
|
2007 |
Johnston B, Vlassov A, Korba B, Ilves H, Kaspar R, Kazakov S, Farrar K, Mukerjee S, Seyhan A. shRNAs Targeting Hepatitis C: Effects of Sequence and Structural Features, and Comparison with siRNA Antiviral Research. 74. DOI: 10.1016/J.Antiviral.2007.01.087 |
0.339 |
|
2007 |
IYER R, PADMANABHAN S, COUGHLIN J, ZHANG G, KIRK C, KORBA B, MORREY J. Initial Pharmacodynamic Evaluation of Orally Bioavailable Prodrugs of SB-9000, a Novel Anti-HBV Agent Antiviral Research. 74: A54-A55. DOI: 10.1016/J.Antiviral.2007.01.074 |
0.385 |
|
2007 |
Korba B, Abigail M, Marc A, Rossignol J. Nitazoxanide is an Effective Antiviral Agent Against Both HBV and HCV replication in vitro Antiviral Research. 74. DOI: 10.1016/J.Antiviral.2007.01.039 |
0.509 |
|
2006 |
Korba BE, Furman PA, Otto MJ. Clevudine: a potent inhibitor of hepatitis B virus in vitro and in vivo. Expert Review of Anti-Infective Therapy. 4: 549-61. PMID 17009935 DOI: 10.1586/14787210.4.4.549 |
0.525 |
|
2005 |
Zhang P, Zhang N, Korba BE, Hosmane RS. Synthesis and in vitro anti-hepatitis B and C virus activities of ring-expanded ('fat') nucleobase analogues containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system. Bioorganic & Medicinal Chemistry Letters. 15: 5397-401. PMID 16213713 DOI: 10.1016/J.Bmcl.2005.09.015 |
0.488 |
|
2005 |
Casey J, Cote PJ, Toshkov IA, Chu CK, Gerin JL, Hornbuckle WE, Tennant BC, Korba BE. Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks. Antimicrobial Agents and Chemotherapy. 49: 4396-9. PMID 16189132 DOI: 10.1128/Aac.49.10.4396-4399.2005 |
0.565 |
|
2005 |
Iyer RP, Padmanabhan S, Zhang G, Morrey JD, Korba BE. Nucleotide analogs as novel anti-hepatitis B virus agents. Current Opinion in Pharmacology. 5: 520-8. PMID 16087397 DOI: 10.1016/J.Coph.2005.04.019 |
0.54 |
|
2005 |
Yang M, Schneller SW, Korba B. 5'-Homoneplanocin A inhibits hepatitis B and hepatitis C. Journal of Medicinal Chemistry. 48: 5043-6. PMID 16033283 DOI: 10.1021/Jm058200E |
0.506 |
|
2005 |
Menne S, Cote PJ, Korba BE, Butler SD, George AL, Tochkov IA, Delaney WE, Xiong S, Gerin JL, Tennant BC. Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection. Antimicrobial Agents and Chemotherapy. 49: 2720-8. PMID 15980342 DOI: 10.1128/Aac.49.7.2720-2728.2005 |
0.544 |
|
2005 |
Okuse C, Rinaudo JA, Farrar K, Wells F, Korba BE. Enhancement of antiviral activity against hepatitis C virus in vitro by interferon combination therapy. Antiviral Research. 65: 23-34. PMID 15652968 DOI: 10.1016/J.Antiviral.2004.09.002 |
0.424 |
|
2004 |
Jacob JR, Korba BE, You JE, Tennant BC, Kim YH. Korean medicinal plant extracts exhibit antiviral potency against viral hepatitis. Journal of Alternative and Complementary Medicine (New York, N.Y.). 10: 1019-26. PMID 15673997 DOI: 10.1089/Acm.2004.10.1019 |
0.596 |
|
2004 |
Korba BE, Cote PJ, Menne S, Toshkov I, Baldwin BH, Wells FV, Tennant BC, Gerin JL. Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection. Antiviral Therapy. 9: 937-52. PMID 15651753 |
0.39 |
|
2004 |
Tennant BC, Toshkov IA, Peek SF, Jacob JR, Menne S, Hornbuckle WE, Schinazi RD, Korba BE, Cote PJ, Gerin JL. Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection. Gastroenterology. 127: S283-93. PMID 15508096 DOI: 10.1053/J.Gastro.2004.09.043 |
0.499 |
|
2004 |
Jacob JR, Korba BE, Cote PJ, Toshkov I, Delaney WE, Gerin JL, Tennant BC. Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model. Antiviral Research. 63: 115-21. PMID 15302140 DOI: 10.1016/J.Antiviral.2004.03.005 |
0.444 |
|
2004 |
Iyer RP, Roland A, Jin Y, Mounir S, Korba B, Julander JG, Morrey JD. Anti-hepatitis B virus activity of ORI-9020, a novel phosphorothioate dinucleotide, in a transgenic mouse model. Antimicrobial Agents and Chemotherapy. 48: 2318-20. PMID 15155244 DOI: 10.1128/Aac.48.6.2318-2320.2004 |
0.514 |
|
2004 |
Iyer RP, Jin Y, Roland A, Morrey JD, Mounir S, Korba B. Phosphorothioate di- and trinucleotides as a novel class of anti-hepatitis B virus agents. Antimicrobial Agents and Chemotherapy. 48: 2199-205. PMID 15155222 DOI: 10.1128/Aac.48.6.2199-2205.2004 |
0.547 |
|
2004 |
Jacob JR, Sterczer A, Toshkov IA, Yeager AE, Korba BE, Cote PJ, Buendia MA, Gerin JL, Tennant BC. Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors. Hepatology (Baltimore, Md.). 39: 1008-16. PMID 15057905 DOI: 10.1002/Hep.20106 |
0.357 |
|
2004 |
Ciancio A, Smedile A, Rizzetto M, Lagget M, Gerin J, Korba B. Identification of HBV DNA sequences that are predictive of response to lamivudine therapy. Hepatology. 39: 64-73. PMID 14752824 DOI: 10.1002/Hep.20019 |
0.471 |
|
2002 |
Menne S, Roneker CA, Tennant BC, Korba BE, Gerin JL, Cote PJ. Immunogenic effects of woodchuck hepatitis virus surface antigen vaccine in combination with antiviral therapy: breaking of humoral and cellular immune tolerance in chronic woodchuck hepatitis virus infection. Intervirology. 45: 237-50. PMID 12566706 DOI: 10.1159/000067914 |
0.445 |
|
2002 |
Hurwitz SJ, Tennant BC, Korba BE, Liberman I, Gerin JL, Schinazi RF. Viral pharmacodynamic model for (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine (emtricitabine) in chronically infected woodchucks. Antiviral Chemistry & Chemotherapy. 13: 165-76. PMID 12448689 DOI: 10.1177/095632020201300303 |
0.489 |
|
2002 |
Tatti KM, Korba BE, Stang HL, Peek S, Gerin JL, Tennant BC, Schinazi RF. Mutations in the conserved woodchuck hepatitis virus polymerase FLLA and YMDD regions conferring resistance to lamivudine. Antiviral Research. 55: 141-50. PMID 12076758 DOI: 10.1016/S0166-3542(02)00019-0 |
0.456 |
|
2002 |
Menne S, Roneker CA, Korba BE, Gerin JL, Tennant BC, Cote PJ. Immunization with surface antigen vaccine alone and after treatment with 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)-uracil (L-FMAU) breaks humoral and cell-mediated immune tolerance in chronic woodchuck hepatitis virus infection. Journal of Virology. 76: 5305-14. PMID 11991959 DOI: 10.1128/Jvi.76.11.5305-5314.2002 |
0.52 |
|
2002 |
Sood RK, Bhadti VS, Fattom AI, Naso RB, Korba BE, Kern ER, Chen HM, Hosmane RS. Novel ring-expanded nucleoside analogs exhibit potent and selective inhibition of hepatitis B virus replication in cultured human hepatoblastoma cells. Antiviral Research. 53: 159-64. PMID 11750942 DOI: 10.1016/S0166-3542(01)00204-2 |
0.485 |
|
2001 |
Bryant ML, Bridges EG, Placidi L, Faraj A, Loi AG, Pierra C, Dukhan D, Gosselin G, Imbach JL, Hernandez B, Juodawlkis A, Tennant B, Korba B, Cote P, Cretton-Scott E, et al. Anti-HBV specific beta-L-2'-deoxynucleosides. Nucleosides, Nucleotides & Nucleic Acids. 20: 597-607. PMID 11563077 DOI: 10.1081/Ncn-100002336 |
0.524 |
|
2001 |
Jin Y, Chen X, Côté M, Roland A, Korba B, Mounir S, Iyer RP. Parallel solid-phase synthesis of nucleoside phosphoramidate libraries. Bioorganic & Medicinal Chemistry Letters. 11: 2057-60. PMID 11514138 DOI: 10.1016/S0960-894X(01)00380-8 |
0.418 |
|
2001 |
Peek SF, Cote PJ, Jacob JR, Toshkov IA, Hornbuckle WE, Baldwin BH, Wells FV, Chu CK, Gerin JL, Tennant BC, Korba BE. Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-beta, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax). Hepatology (Baltimore, Md.). 33: 254-66. PMID 11124844 DOI: 10.1053/Jhep.2001.20899 |
0.551 |
|
2001 |
Bryant ML, Bridges EG, Placidi L, Faraj A, Loi AG, Pierra C, Dukhan D, Gosselin G, Imbach JL, Hernandez B, Juodawlkis A, Tennant B, Korba B, Cote P, Marion P, et al. Antiviral L-nucleosides specific for hepatitis B virus infection. Antimicrobial Agents and Chemotherapy. 45: 229-35. PMID 11120971 DOI: 10.1128/Aac.45.1.229-235.2001 |
0.486 |
|
2000 |
Schmidt K, Korba B. Hepatitis B virus cell culture assays for antiviral activity. Methods in Molecular Medicine. 24: 51-67. PMID 21331899 DOI: 10.1385/1-59259-245-7:51 |
0.543 |
|
2000 |
Cote PJ, Toshkov I, Bellezza C, Ascenzi M, Roneker C, Ann Graham L, Baldwin BH, Gaye K, Nakamura I, Korba BE, Tennant BC, Gerin JL. Temporal pathogenesis of experimental neonatal woodchuck hepatitis virus infection: increased initial viral load and decreased severity of acute hepatitis during the development of chronic viral infection. Hepatology (Baltimore, Md.). 32: 807-17. PMID 11003627 DOI: 10.1053/Jhep.2000.17681 |
0.474 |
|
2000 |
Hostetler KY, Beadle JR, Hornbuckle WE, Bellezza CA, Tochkov IA, Cote PJ, Gerin JL, Korba BE, Tennant BC. Antiviral activities of oral 1-O-hexadecylpropanediol-3-phosphoacyclovir and acyclovir in woodchucks with chronic woodchuck hepatitis virus infection Antimicrobial Agents and Chemotherapy. 44: 1964-1969. PMID 10858362 DOI: 10.1128/Aac.44.7.1964-1969.2000 |
0.565 |
|
2000 |
Korba BE, Schinazi RF, Cote P, Tennant BC, Gerin JL. Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucks Antimicrobial Agents and Chemotherapy. 44: 1757-1760. PMID 10817750 DOI: 10.1128/Aac.44.6.1757-1760.2000 |
0.586 |
|
2000 |
Korba BE, Cote P, Hornbuckle W, Tennant BC, Gerin JL. Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans. Hepatology (Baltimore, Md.). 31: 1165-75. PMID 10796894 DOI: 10.1053/He.2000.5982 |
0.551 |
|
2000 |
Korba BE, Cote P, Hornbuckle W, Schinazi R, Gerin JL, Tennant BC. Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks Antiviral Research. 45: 19-32. PMID 10774587 DOI: 10.1016/S0166-3542(99)00072-8 |
0.564 |
|
2000 |
Cote PJ, Korba BE, Miller RH, Jacob JR, Baldwin BH, Hornbuckle WE, Purcell RH, Tennant BC, Gerin JL. Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection. Hepatology (Baltimore, Md.). 31: 190-200. PMID 10613745 DOI: 10.1002/Hep.510310128 |
0.441 |
|
2000 |
Korba BE, Cote P, Hornbuckle W, Schinazi R, Gerin JL, Tennant BC. Corrigendum to “Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks” Antiviral Research. 45: 155-156. DOI: 10.1016/S0166-3542(00)00078-4 |
0.379 |
|
1999 |
Morrey JD, Bailey KW, Korba BE, Sidwell RW. Utilization of transgenic mice replicating high levels of hepatitis B virus for antiviral evaluation of lamivudine Antiviral Research. 42: 97-108. PMID 10389653 DOI: 10.1016/S0166-3542(99)00009-1 |
0.502 |
|
1999 |
Périgaud C, Gosselin G, Girardet JL, Korba BE, Imbach JL. The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir: part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir. Antiviral Research. 40: 167-78. PMID 10027651 DOI: 10.1016/S0166-3542(98)00059-X |
0.554 |
|
1998 |
Zembower DE, Lin YM, Flavin MT, Chen FC, Korba BE. Robustaflavone, a potential non-nucleoside anti-hepatitis B agent. Antiviral Research. 39: 81-8. PMID 9806485 DOI: 10.1016/S0166-3542(98)00033-3 |
0.474 |
|
1998 |
Hurwitz SJ, Tennant BC, Korba BE, Gerin JL, Schinazi RF. Pharmacodynamics of (-)-β-2',3'-dideoxy-3'-thiacytidine in chronically virus-infected woodchucks compared to its pharmacodynamics in humans Antimicrobial Agents and Chemotherapy. 42: 2804-2809. PMID 9797207 DOI: 10.1128/Aac.42.11.2804 |
0.506 |
|
1998 |
Seley KL, Schneller SW, De Clercq E, Rattendi D, Lane S, Bacchi CJ, Korba B. The importance of the 4'-hydroxyl hydrogen for the anti-trypanosomal and antiviral properties of (+)-5'-noraristeromycin and two 7-deaza analogues Bioorganic and Medicinal Chemistry. 6: 797-801. PMID 9681145 DOI: 10.1016/S0968-0896(98)00036-4 |
0.316 |
|
1998 |
Tennant BC, Baldwin BH, Graham LA, Ascenzi MA, Hornbuckle WE, Rowland PH, Tochkov IA, Yeager AE, Erb HN, Colacino JM, Lopez C, Engelhardt JA, Bowsher RR, Richardson FC, Lewis W, ... ... Korba BE, et al. Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection. Hepatology (Baltimore, Md.). 28: 179-91. PMID 9657111 DOI: 10.1002/Hep.510280124 |
0.462 |
|
1998 |
Block TM, Lu X, Mehta AS, Blumberg BS, Tennant B, Ebling M, Korba B, Lansky DM, Jacob GS, Dwek RA. Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking. Nature Medicine. 4: 610-4. PMID 9585237 DOI: 10.1038/Nm0598-610 |
0.515 |
|
1997 |
Valette G, Girardet J, Pompon A, Périgaud C, Gosselin G, Korba B, Hantz O, Imbach J. The Pronucleotide Approach. III. Synthesis, Anti-HBV Activity and Stability Studies of the Bis(S-pivaloyl-2-thioethyl) Phosphotriester Derivative of Acyclovir Nucleosides, Nucleotides & Nucleic Acids. 16: 1331-1335. DOI: 10.1080/07328319708006182 |
0.425 |
|
1997 |
Mansour TS, Evans CA, Siddiqui MA, Charron M, Zacharie B, Nguyen-Ba N, Lee N, Korba B. Structure-Activity Relationship of Pyrimidine Heterosubstituted Nucleoside Analogues Nucleosides, Nucleotides & Nucleic Acids. 16: 993-1001. DOI: 10.1080/07328319708006122 |
0.428 |
|
1997 |
Seley KL, Schneller SW, Korba B. A 5′-noraristeromycin enantiomer with activity towards hepatitis B virus Nucleosides and Nucleotides. 16: 2095-2099. DOI: 10.1080/07328319708002560 |
0.547 |
|
1997 |
Lin YM, Zembower DE, Flavin MT, Schure RM, Anderson HM, Korba BE, Chen FC. Robustaflavone, a naturally occurring biflavanoid, is a potent non-nucleoside inhibitor of hepatitis B virus replication in vitro Bioorganic and Medicinal Chemistry Letters. 7: 2325-2328. DOI: 10.1016/S0960-894X(97)00422-8 |
0.504 |
|
1997 |
Mansour TS, Evans CA, Charron M, Korba BE. Discovery of imidazo[1,2-c]pyrimidin-5(6H)-one heterosubstituted nucleoside analogues with potent activity against human hepatitis B virus in vitro Bioorganic and Medicinal Chemistry Letters. 7: 303-308. DOI: 10.1016/S0960-894X(97)00001-2 |
0.52 |
|
1996 |
Korba BE, Boyd MR. Penciclovir is a selective inhibitor of hepatitis B virus replication in cultured human hepatoblastoma cells Antimicrobial Agents and Chemotherapy. 40: 1282-1284. PMID 8723485 DOI: 10.1128/Aac.40.5.1282 |
0.542 |
|
1996 |
Korba BE. In vitro evaluation of combination therapies against hepatitis B virus replication Antiviral Research. 29: 49-51. PMID 8721544 DOI: 10.1016/0166-3542(95)00915-9 |
0.536 |
|
1995 |
Korba BE, Gerin JL. Antisense oligonucleotides are effective inhibitors of hepatitis B virus replication in vitro Antiviral Research. 28: 225-242. PMID 8629815 DOI: 10.1016/0166-3542(95)00050-V |
0.538 |
|
1994 |
Hostetler KY, Korba BE, Sridhar CN, Gardner MF. Antiviral activity of phosphatidyl-dideoxycytidine in hepatitis B-infected cells and enhanced hepatic uptake in mice Antiviral Research. 24: 59-67. PMID 7944313 DOI: 10.1016/0166-3542(94)90052-3 |
0.494 |
|
1992 |
Müller C, Bergmann KF, Gerin JL, Korba BE. Production of Hepatitis B Virus by Stably Transfected Monocytic Cell Line U-937: A Model for Extrahepatic Hepatitis B Virus Replication The Journal of Infectious Diseases. 165: 929-933. PMID 1569345 DOI: 10.1093/Infdis/165.5.929 |
0.508 |
|
1992 |
Gerin JL, Korba BE, Cote PJ, Tennant BC. A preliminary report of a controlled study of thymosin alpha-1 in the woodchuck model of hepadnavirus infection Advances in Experimental Medicine and Biology. 312: 121-123. PMID 1514437 DOI: 10.1007/978-1-4615-3462-4_11 |
0.478 |
|
1992 |
Cote PJ, Korba BE, Baldwin B, Hornbuckle WE, Tennant BC, Gerin JL. Immunosuppression with Cyclosporine during the Incubation Period of Experimental Woodchuck Hepatitis Virus Infection Increases the Frequency of Chronic Infection in Adult Woodchucks The Journal of Infectious Diseases. 166: 628-631. PMID 1500746 DOI: 10.1093/Infdis/166.3.628 |
0.407 |
|
1992 |
Korba BE, Gerin JL. Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication. Antiviral Research. 19: 55-70. PMID 1444322 DOI: 10.1016/0166-3542(92)90056-B |
0.507 |
|
1991 |
Korba BE, Milman G. A cell culture assay for compounds which inhibit hepatitis B virus replication. Antiviral Research. 15: 217-228. PMID 1716089 DOI: 10.1016/0166-3542(91)90068-3 |
0.516 |
|
1991 |
Korba B, Tennant B, Cote P, Gerin J. Treatment of chronic carriers of woodchuck hepatitis virus infection with thymosin alpha-1 Antiviral Research. 15: 131. DOI: 10.1016/0166-3542(91)90250-U |
0.481 |
|
1991 |
Tennant BC, Mrosovsky N, McLean K, Cote PJ, Korba BE, Engle RE, Gerin JL, Wright J, Michener GR, Uhl E, King JM. Hepatocellular carcinoma in Richardson's ground squirrels (Spermophilus richardsonii): evidence for association with hepatitis B-like virus infection. Hepatology. 13: 1215-1221. DOI: 10.1002/Hep.1840130630 |
0.5 |
|
1990 |
Korba BE, Brown TL, Wells FV, Baldwin B, Cote PJ, Steinberg H, Tennant BC, Gerin JL. Natural history of experimental woodchuck hepatitis virus infection: molecular virologic features of the pancreas, kidney, ovary, and testis. Journal of Virology. 64: 4499-4506. PMID 2384922 DOI: 10.1128/Jvi.64.9.4499-4506.1990 |
0.448 |
|
1990 |
Miller RH, Girones R, Cote PJ, Hornbuckle WE, Chestnut T, Baldwin BH, Korba BE, Tennant BC, Gerin JL, Purcell RH. Evidence against a requisite role for defective virus in the establishment of persistent hepadnavirus infections. Proceedings of the National Academy of Sciences of the United States of America. 87: 9329-32. PMID 2251274 DOI: 10.1073/Pnas.87.23.9329 |
0.47 |
|
1990 |
Korba BE, Boumpas D, Mann D, Yoakum GH. Direct modulation of HBV surface antigen in a human, HBsAg-producing hepatocellular carcinoma cell line by alpha, beta, or gamma interferons. Journal of Medical Virology. 31: 272-276. PMID 2176672 DOI: 10.1002/Jmv.1890310406 |
0.428 |
|
1989 |
Negro F, Korba BE, Forzani B, Baroudy BM, Brown TL, Gerin JL, Ponzetto A. Hepatitis delta virus (HDV) and woodchuck hepatitis virus (WHV) nucleic acids in tissues of HDV-infected chronic WHV carrier woodchucks. Journal of Virology. 63: 1612-1618. PMID 2926865 DOI: 10.1128/Jvi.63.4.1612-1618.1989 |
0.439 |
|
1989 |
Korba BE, Cote PJ, Wells FV, Baldwin B, Popper H, Purcell RH, Tennant BC, Gerin JL. Natural history of woodchuck hepatitis virus infections during the course of experimental viral infection: molecular virologic features of the liver and lymphoid tissues. Journal of Virology. 63: 1360-1370. PMID 2915383 DOI: 10.1128/Jvi.63.3.1360-1370.1989 |
0.453 |
|
1989 |
Korba BE, Cote PJ, Shapiro M, Purcell RH, Gerin JL. In vitro production of infectious woodchuck hepatitis virus by lipopolysaccharide-stimulated peripheral blood lymphocytes. The Journal of Infectious Diseases. 160: 572-6. PMID 2794556 DOI: 10.1093/Infdis/160.4.572 |
0.465 |
|
1988 |
Korba BE, Gowans EJ, Wells FV, Tennant BC, Clarke R, Gerin JL. Systemic distribution of woodchuck hepatitis virus in the tissues of experimentally infected woodchucks Virology. 165: 172-181. PMID 3388768 DOI: 10.1016/0042-6822(88)90670-8 |
0.407 |
|
1988 |
Korba B, Cote P, Gerin J. Mitogen-induced replication of woodchuck hepatitis virus in cultured peripheral blood lymphocytes. Science. 241: 1213-1216. PMID 3261887 DOI: 10.1126/Science.3261887 |
0.426 |
|
1987 |
Korba BE, Wells F, Tennant BC, Cote PJ, Gerin JL. Lymphoid cells in the spleens of woodchuck hepatitis virus-infected woodchucks are a site of active viral replication Journal of Virology. 61: 1318-1324. PMID 3573141 DOI: 10.1128/Jvi.61.5.1318-1324.1987 |
0.438 |
|
1986 |
Korba BE, Wells F, Tennant BC, Yoakum GH, Purcell RH, Gerin JL. Hepadnavirus infection of peripheral blood lymphocytes in vivo: woodchuck and chimpanzee models of viral hepatitis. Journal of Virology. 58: 1-8. PMID 3485201 DOI: 10.1128/Jvi.58.1.1-8.1986 |
0.494 |
|
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