Sarah M. Fortune - Publications

Affiliations: 
Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Microbiology Biology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Carey AF, Rock JM, Krieger IV, Chase MR, Fernandez-Suarez M, Gagneux S, Sacchettini JC, Ioerger TR, Fortune SM. Correction: TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities. Plos Pathogens. 15: e1007846. PMID 31163081 DOI: 10.1371/journal.ppat.1007846  0.36
2018 Gerrick ER, Barbier T, Chase MR, Xu R, François J, Lin VH, Szucs MJ, Rock JM, Ahmad R, Tjaden B, Livny J, Fortune SM. Small RNA profiling in identifies MrsI as necessary for an anticipatory iron sparing response. Proceedings of the National Academy of Sciences of the United States of America. PMID 29871950 DOI: 10.1073/pnas.1718003115  0.36
2018 Sakatos A, Babunovic GH, Chase MR, Dills A, Leszyk J, Rosebrock T, Bryson B, Fortune SM. Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria. Science Advances. 4: eaao1478. PMID 29732401 DOI: 10.1126/sciadv.aao1478  0.36
2018 Carey AF, Rock JM, Krieger IV, Chase MR, Fernandez-Suarez M, Gagneux S, Sacchettini JC, Ioerger TR, Fortune SM. TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities. Plos Pathogens. 14: e1006939. PMID 29505613 DOI: 10.1371/journal.ppat.1006939  0.36
2018 Rubin EJ, Fortune SM. Misunderstanding the goals of animal research. Bmj (Clinical Research Ed.). 360: k759. PMID 29467126  0.4
2017 Franchina FA, Mellors TR, Aliyeva M, Wagner J, Daphtary N, Lundblad L, Fortune SM, Rubin EJ, Hill JE. Towards the use of breath for detecting mycobacterial infection: a case study in a Murine model. Journal of Breath Research. PMID 29219122 DOI: 10.1088/1752-7163/aaa016  0.4
2017 Warner DF, Rock JM, Fortune SM, Mizrahi V. DNA Replication Fidelity in the Mycobacterium tuberculosis Complex. Advances in Experimental Medicine and Biology. 1019: 247-262. PMID 29116639 DOI: 10.1007/978-3-319-64371-7_13  0.32
2017 Martin CJ, Cadena AM, Leung VW, Lin PL, Maiello P, Hicks N, Chase MR, Flynn JL, Fortune SM. Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis. Mbio. 8. PMID 28487426 DOI: 10.1128/mBio.00312-17  0.36
2017 Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM. Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform. Nature Microbiology. 2: 16274. PMID 28165460 DOI: 10.1038/nmicrobiol.2016.274  0.56
2017 DeJesus MA, Gerrick ER, Xu W, Park SW, Long JE, Boutte CC, Rubin EJ, Schnappinger D, Ehrt S, Fortune SM, Sassetti CM, Ioerger TR. Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis. Mbio. 8. PMID 28096490 DOI: 10.1128/mBio.02133-16  0.56
2016 Lu LL, Chung AW, Rosebrock TR, Ghebremichael M, Yu WH, Grace PS, Schoen MK, Tafesse F, Martin C, Leung V, Mahan AE, Sips M, Kumar MP, Tedesco J, Robinson H, ... ... Fortune SM, et al. A Functional Role for Antibodies in Tuberculosis. Cell. PMID 27667685 DOI: 10.1016/j.cell.2016.08.072  0.56
2016 Boutte CC, Baer CE, Papavinasasundaram K, Liu W, Chase MR, Meniche X, Fortune SM, Sassetti CM, Ioerger TR, Rubin EJ. A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis. Elife. 5. PMID 27304077 DOI: 10.7554/eLife.14590  0.56
2016 Lahiri N, Shah RR, Layre E, Young D, Ford C, Murray MB, Fortune SM, Moody DB. Rifampin Resistance Mutations are Associated with Broad Chemical Remodeling of Mycobacterium tuberculosis. The Journal of Biological Chemistry. PMID 27226566 DOI: 10.1074/jbc.M116.716704  0.32
2015 Martin CJ, Carey AF, Fortune SM. A bug's life in the granuloma. Seminars in Immunopathology. PMID 26577238 DOI: 10.1007/s00281-015-0533-1  0.56
2015 Shell SS, Wang J, Lapierre P, Mir M, Chase MR, Pyle MM, Gawande R, Ahmad R, Sarracino DA, Ioerger TR, Fortune SM, Derbyshire KM, Wade JT, Gray TA. Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape. Plos Genetics. 11: e1005641. PMID 26536359 DOI: 10.1371/journal.pgen.1005641  0.36
2015 Kieser KJ, Boutte CC, Kester JC, Baer CE, Barczak AK, Meniche X, Chao MC, Rego EH, Sassetti CM, Fortune SM, Rubin EJ. Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria. Plos Pathogens. 11: e1005010. PMID 26114871 DOI: 10.1371/journal.ppat.1005010  0.56
2015 Datta P, Ravi J, Guerrini V, Chauhan R, Neiditch MB, Shell SS, Fortune SM, Hancioglu B, Igoshin OA, Gennaro ML. The Psp system of Mycobacterium tuberculosis integrates envelope stress-sensing and envelope-preserving functions. Molecular Microbiology. PMID 25899163 DOI: 10.1111/mmi.13037  0.56
2015 Rock JM, Lang UF, Chase MR, Ford CB, Gerrick ER, Gawande R, Coscolla M, Gagneux S, Fortune SM, Lamers MH. DNA replication fidelity in Mycobacterium tuberculosis is mediated by an ancestral prokaryotic proofreader. Nature Genetics. 47: 677-81. PMID 25894501 DOI: 10.1038/ng.3269  0.36
2015 Shell SS, Chase MR, Ioerger TR, Fortune SM. RNA sequencing for transcript 5'-end mapping in mycobacteria. Methods in Molecular Biology (Clifton, N.J.). 1285: 31-45. PMID 25779309 DOI: 10.1007/978-1-4939-2450-9_3  0.56
2015 Gideon HP, Phuah J, Myers AJ, Bryson BD, Rodgers MA, Coleman MT, Maiello P, Rutledge T, Marino S, Fortune SM, Kirschner DE, Lin PL, Flynn JL. Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. Plos Pathogens. 11: e1004603. PMID 25611466 DOI: 10.1371/journal.ppat.1004603  0.56
2015 Ramsdell TL, Huppert LA, Sysoeva TA, Fortune SM, Burton BM. Linked domain architectures allow for specialization of function in the FtsK/SpoIIIE ATPases of ESX secretion systems. Journal of Molecular Biology. 427: 1119-32. PMID 24979678 DOI: 10.1016/j.jmb.2014.06.013  0.56
2014 Huppert LA, Ramsdell TL, Chase MR, Sarracino DA, Fortune SM, Burton BM. The ESX system in Bacillus subtilis mediates protein secretion. Plos One. 9: e96267. PMID 24798022 DOI: 10.1371/journal.pone.0096267  0.56
2014 Layre E, Lee HJ, Young DC, Martinot AJ, Buter J, Minnaard AJ, Annand JW, Fortune SM, Snider BB, Matsunaga I, Rubin EJ, Alber T, Moody DB. Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c. Proceedings of the National Academy of Sciences of the United States of America. 111: 2978-83. PMID 24516143 DOI: 10.1073/pnas.1315883111  0.56
2014 Lin PL, Ford CB, Coleman MT, Myers AJ, Gawande R, Ioerger T, Sacchettini J, Fortune SM, Flynn JL. Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing. Nature Medicine. 20: 75-9. PMID 24336248 DOI: 10.1038/nm.3412  0.56
2013 Shell SS, Prestwich EG, Baek SH, Shah RR, Sassetti CM, Dedon PC, Fortune SM. DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis. Plos Pathogens. 9: e1003419. PMID 23853579 DOI: 10.1371/journal.ppat.1003419  0.56
2013 Ford CB, Shah RR, Maeda MK, Gagneux S, Murray MB, Cohen T, Johnston JC, Gardy J, Lipsitch M, Fortune SM. Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis. Nature Genetics. 45: 784-90. PMID 23749189 DOI: 10.1038/ng.2656  0.56
2013 Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H, Weissleder R. Magnetic barcode assay for genetic detection of pathogens. Nature Communications. 4: 1752. PMID 23612293 DOI: 10.1038/ncomms2745  0.56
2013 Ragheb MN, Ford CB, Chase MR, Lin PL, Flynn JL, Fortune SM. The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosis from cynomolgus macaque infection. Bmc Genomics. 14: 145. PMID 23496945 DOI: 10.1186/1471-2164-14-145  0.56
2013 Chao MC, Kieser KJ, Minami S, Mavrici D, Aldridge BB, Fortune SM, Alber T, Rubin EJ. Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria. Plos Pathogens. 9: e1003197. PMID 23468634 DOI: 10.1371/journal.ppat.1003197  0.56
2012 Martin CJ, Booty MG, Rosebrock TR, Nunes-Alves C, Desjardins DM, Keren I, Fortune SM, Remold HG, Behar SM. Efferocytosis is an innate antibacterial mechanism. Cell Host & Microbe. 12: 289-300. PMID 22980326 DOI: 10.1016/j.chom.2012.06.010  0.56
2012 Lee HJ, Lang PT, Fortune SM, Sassetti CM, Alber T. Cyclic AMP regulation of protein lysine acetylation in Mycobacterium tuberculosis. Nature Structural & Molecular Biology. 19: 811-8. PMID 22773105 DOI: 10.1038/nsmb.2318  0.56
2012 Wirth SE, Krywy JA, Aldridge BB, Fortune SM, Fernandez-Suarez M, Gray TA, Derbyshire KM. Polar assembly and scaffolding proteins of the virulence-associated ESX-1 secretory apparatus in mycobacteria. Molecular Microbiology. 83: 654-64. PMID 22233444 DOI: 10.1111/j.1365-2958.2011.07958.x  0.56
2012 Aldridge BB, Fernandez-Suarez M, Heller D, Ambravaneswaran V, Irimia D, Toner M, Fortune SM. Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility. Science (New York, N.Y.). 335: 100-4. PMID 22174129 DOI: 10.1126/science.1216166  0.56
2011 Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R. Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance. Bioconjugate Chemistry. 22: 2390-4. PMID 22043803 DOI: 10.1021/bc200490r  0.56
2011 Ford CB, Lin PL, Chase MR, Shah RR, Iartchouk O, Galagan J, Mohaideen N, Ioerger TR, Sacchettini JC, Lipsitch M, Flynn JL, Fortune SM. Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection. Nature Genetics. 43: 482-6. PMID 21516081 DOI: 10.1038/ng.811  0.56
2011 Woodworth JS, Shin D, Volman M, Nunes-Alves C, Fortune SM, Behar SM. Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination. Journal of Immunology (Baltimore, Md. : 1950). 186: 1627-37. PMID 21178003 DOI: 10.4049/jimmunol.1002911  0.56
2010 Fortune SM, Rubin EJ. Host transcription in active and latent tuberculosis. Genome Biology. 11: 135. PMID 20920149 DOI: 10.1186/gb-2010-11-9-135  0.56
2010 Garces A, Atmakuri K, Chase MR, Woodworth JS, Krastins B, Rothchild AC, Ramsdell TL, Lopez MF, Behar SM, Sarracino DA, Fortune SM. EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity. Plos Pathogens. 6: e1000957. PMID 20585630 DOI: 10.1371/journal.ppat.1000957  0.56
2009 Bitter W, Houben EN, Bottai D, Brodin P, Brown EJ, Cox JS, Derbyshire K, Fortune SM, Gao LY, Liu J, Gey van Pittius NC, Pym AS, Rubin EJ, Sherman DR, Cole ST, et al. Systematic genetic nomenclature for type VII secretion systems. Plos Pathogens. 5: e1000507. PMID 19876390 DOI: 10.1371/journal.ppat.1000507  0.56
2009 Siegrist MS, Unnikrishnan M, McConnell MJ, Borowsky M, Cheng TY, Siddiqi N, Fortune SM, Moody DB, Rubin EJ. Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition. Proceedings of the National Academy of Sciences of the United States of America. 106: 18792-7. PMID 19846780 DOI: 10.1073/pnas.0900589106  0.56
2008 Woodworth JS, Fortune SM, Behar SM. Bacterial protein secretion is required for priming of CD8+ T cells specific for the Mycobacterium tuberculosis antigen CFP10. Infection and Immunity. 76: 4199-205. PMID 18591224 DOI: 10.1128/IAI.00307-08  0.56
2007 Fortune SM, Rubin EJ. The complex relationship between mycobacteria and macrophages: it's not all bliss. Cell Host & Microbe. 2: 5-6. PMID 18005712 DOI: 10.1016/j.chom.2007.06.008  0.56
2007 Hett EC, Chao MC, Steyn AJ, Fortune SM, Deng LL, Rubin EJ. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Molecular Microbiology. 66: 658-68. PMID 17919286 DOI: 10.1111/j.1365-2958.2007.05945.x  0.56
2006 Joshi SM, Pandey AK, Capite N, Fortune SM, Rubin EJ, Sassetti CM. Characterization of mycobacterial virulence genes through genetic interaction mapping. Proceedings of the National Academy of Sciences of the United States of America. 103: 11760-5. PMID 16868085 DOI: 10.1073/pnas.0603179103  0.56
2006 Fortune SM, Chase MR, Rubin EJ. Dividing oceans into pools: strategies for the global analysis of bacterial genes. Microbes and Infection / Institut Pasteur. 8: 1631-6. PMID 16697239 DOI: 10.1016/j.micinf.2005.11.015  0.56
2004 Fortune SM, Solache A, Jaeger A, Hill PJ, Belisle JT, Bloom BR, Rubin EJ, Ernst JD. Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 172: 6272-80. PMID 15128816  0.56
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