Dana B. Lacy - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Microbiology Biology

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sheedlo MJ, Durie CL, Chung JM, Chang L, Roberts J, Swanson M, Lacy DB, Ohi MD. Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife. 10. PMID 34519271 DOI: 10.7554/eLife.70427  0.316
2020 Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD. Structure of the Helicobacter pylori Cag Type IV Secretion System Biophysical Journal. 118: 295a. DOI: 10.2210/Pdb6Oeg/Pdb  0.465
2019 Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD. Structure of the Cag Type IV secretion system. Elife. 8. PMID 31210639 DOI: 10.7554/Elife.47644  0.463
2019 Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD. Author response: Structure of the Helicobacter pylori Cag type IV secretion system Elife. DOI: 10.7554/Elife.47644.043  0.424
2016 González-Rivera C, Campbell AM, Rutherford SA, Pyburn TM, Foegeding NJ, Barke TL, Spiller BW, McClain MS, Ohi MD, Lacy DB, Cover TL. A non-oligomerizing mutant form of Helicobacter pylori VacA allows structural analysis of the p33 domain. Infection and Immunity. PMID 27382020 DOI: 10.1128/Iai.00254-16  0.483
2014 Zhang Z, Park M, Tam J, Auger A, Beilhartz GL, Lacy DB, Melnyk RA. Translocation domain mutations affecting cellular toxicity identify the Clostridium difficile toxin B pore. Proceedings of the National Academy of Sciences of the United States of America. 111: 3721-6. PMID 24567384 DOI: 10.1073/Pnas.1400680111  0.311
2013 Chambers MG, Pyburn TM, González-Rivera C, Collier SE, Eli I, Yip CK, Takizawa Y, Lacy DB, Cover TL, Ohi MD. Structural analysis of the oligomeric states of Helicobacter pylori VacA toxin. Journal of Molecular Biology. 425: 524-35. PMID 23178866 DOI: 10.1016/J.Jmb.2012.11.020  0.513
2012 Pruitt RN, Chumbler NM, Rutherford SA, Farrow MA, Friedman DB, Spiller B, Lacy DB. Structural determinants of Clostridium difficile toxin A glucosyltransferase activity. The Journal of Biological Chemistry. 287: 8013-20. PMID 22267739 DOI: 10.1074/Jbc.M111.298414  0.314
2010 Gangwer KA, Shaffer CL, Suerbaum S, Lacy DB, Cover TL, Bordenstein SR. Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA. Journal of Bacteriology. 192: 6126-35. PMID 20870762 DOI: 10.1128/Jb.01081-10  0.302
2010 Pruitt RN, Chambers MG, Ng KK, Ohi MD, Lacy DB. Structural organization of the functional domains of Clostridium difficile toxins A and B. Proceedings of the National Academy of Sciences of the United States of America. 107: 13467-72. PMID 20624955 DOI: 10.1073/Pnas.1002199107  0.361
2010 González-Rivera C, Gangwer KA, McClain MS, Eli IM, Chambers MG, Ohi MD, Lacy DB, Cover TL. Reconstitution of Helicobacter pylori VacA toxin from purified components. Biochemistry. 49: 5743-52. PMID 20527875 DOI: 10.1021/Bi100618G  0.393
2010 Ivie SE, McClain MS, Algood HM, Lacy DB, Cover TL. Analysis of a beta-helical region in the p55 domain of Helicobacter pylori vacuolating toxin. Bmc Microbiology. 10: 60. PMID 20178613 DOI: 10.1186/1471-2180-10-60  0.469
2009 Pruitt RN, Chagot B, Cover M, Chazin WJ, Spiller B, Lacy DB. Structure-function analysis of inositol hexakisphosphate-induced autoprocessing in Clostridium difficile toxin A. The Journal of Biological Chemistry. 284: 21934-40. PMID 19553670 DOI: 10.1074/Jbc.M109.018929  0.407
2008 Ivie SE, McClain MS, Torres VJ, Algood HM, Lacy DB, Yang R, Blanke SR, Cover TL. Helicobacter pylori VacA subdomain required for intracellular toxin activity and assembly of functional oligomeric complexes. Infection and Immunity. 76: 2843-51. PMID 18443094 DOI: 10.1128/Iai.01664-07  0.412
2007 Gangwer KA, Mushrush DJ, Stauff DL, Spiller B, McClain MS, Cover TL, Lacy DB. Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain. Proceedings of the National Academy of Sciences of the United States of America. 104: 16293-8. PMID 17911250 DOI: 10.1073/Pnas.0707447104  0.362
2004 Lacy DB, Wigelsworth DJ, Scobie HM, Young JA, Collier RJ. Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor. Proceedings of the National Academy of Sciences of the United States of America. 101: 6367-72. PMID 15079089 DOI: 10.1073/Pnas.0401506101  0.359
2002 Lacy DB, Collier RJ. Structure and function of anthrax toxin. Current Topics in Microbiology and Immunology. 271: 61-85. PMID 12224524 DOI: 10.1007/978-3-662-05767-4_4  0.319
2001 Pannifer AD, Wong TY, Schwarzenbacher R, Renatus M, Petosa C, Bienkowska J, Lacy DB, Collier RJ, Park S, Leppla SH, Hanna P, Liddington RC. Crystal structure of the anthrax lethal factor. Nature. 414: 229-33. PMID 11700563 DOI: 10.1038/N35101998  0.331
1999 Lacy DB, Stevens RC. Sequence homology and structural analysis of the clostridial neurotoxins. Journal of Molecular Biology. 291: 1091-104. PMID 10518945 DOI: 10.1006/Jmbi.1999.2945  0.341
1998 Lacy DB, Tepp W, Cohen AC, DasGupta BR, Stevens RC. Crystal structure of botulinum neurotoxin type A and implications for toxicity. Nature Structural Biology. 5: 898-902. PMID 9783750 DOI: 10.1038/2338  0.369
1997 Lacy DB, Stevens RC. Recombinant expression and purification of the botulinum neurotoxin type A translocation domain. Protein Expression and Purification. 11: 195-200. PMID 9367816 DOI: 10.1006/Prep.1997.0772  0.306
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