Xingxing Zang - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Immunology, Microbiology Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Li L, Han L, Sun F, Zhou J, Ohaegbulam KC, Tang X, Zang X, Steinbrecher KA, Qu Z, Xiao G. NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8 T cells for tumor promotion. Oncoimmunology. 7: e1435250. PMID 29872577 DOI: 10.1080/2162402X.2018.1435250  0.44
2017 Ohaegbulam KC, Liu W, Jeon H, Almo SC, Zang X. Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells. Oncotarget. 8: 82740-82753. PMID 29137299 DOI: 10.18632/oncotarget.21098  0.52
2016 Koirala P, Roth ME, Gill J, Chinai JM, Ewart MR, Piperdi S, Geller DS, Hoang BH, Fatakhova YV, Ghorpade M, Zang X, Gorlick R. HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival. Scientific Reports. 6: 31154. PMID 27531281 DOI: 10.1038/srep31154  0.52
2016 Picarda E, Ohaegbulam KC, Zang X. Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27208063 DOI: 10.1158/1078-0432.CCR-15-2428  0.44
2016 Yao Y, Ye H, Qi Z, Mo L, Yue Q, Baral A, Hoon DS, Vera JC, Heiss JD, Chen CC, Hua W, Zhang J, Jin K, Wang Y, Zang X, et al. B7-H4(B7x)-Mediated Cross-talk between Glioma-Initiating Cells and Macrophages via the IL6/JAK/STAT3 Pathway Lead to Poor Prognosis in Glioma Patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27001312 DOI: 10.1158/1078-0432.CCR-15-0858  0.52
2015 Chinai JM, Janakiram M, Chen F, Chen W, Kaplan M, Zang X. New immunotherapies targeting the PD-1 pathway. Trends in Pharmacological Sciences. 36: 587-95. PMID 26162965 DOI: 10.1016/j.tips.2015.06.005  0.52
2015 Zhao H, Bauzon F, Bi E, Yu JJ, Fu H, Lu Z, Cui J, Jeon H, Zang X, Ye BH, Zhu L. Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age. The Journal of Biological Chemistry. 290: 5797-809. PMID 25583987 DOI: 10.1074/jbc.M114.625350  0.52
2015 Janakiram M, Chinai JM, Fineberg S, Fiser A, Montagna C, Medavarapu R, Castano E, Jeon H, Ohaegbulam KC, Zhao R, Zhao A, Almo SC, Sparano JA, Zang X. Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2359-66. PMID 25549724 DOI: 10.1158/1078-0432.CCR-14-1495  0.52
2015 Ohaegbulam KC, Assal A, Lazar-Molnar E, Yao Y, Zang X. Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway. Trends in Molecular Medicine. 21: 24-33. PMID 25440090 DOI: 10.1016/j.molmed.2014.10.009  0.44
2014 Jeon H, Vigdorovich V, Garrett-Thomson SC, Janakiram M, Ramagopal UA, Abadi YM, Lee JS, Scandiuzzi L, Ohaegbulam KC, Chinai JM, Zhao R, Yao Y, Mao Y, Sparano JA, Almo SC, ... Zang X, et al. Structure and cancer immunotherapy of the B7 family member B7x. Cell Reports. 9: 1089-98. PMID 25437562 DOI: 10.1016/j.celrep.2014.09.053  0.52
2014 Scandiuzzi L, Ghosh K, Hofmeyer KA, Abadi YM, Lázár-Molnár E, Lin EY, Liu Q, Jeon H, Almo SC, Chen L, Nathenson SG, Zang X. Tissue-expressed B7-H1 critically controls intestinal inflammation. Cell Reports. 6: 625-32. PMID 24529703 DOI: 10.1016/j.celrep.2014.01.020  0.52
2013 Singh M, Ramos I, Asafu-Adjei D, Quispe-Tintaya W, Chandra D, Jahangir A, Zang X, Aggarwal BB, Gravekamp C. Curcumin improves the therapeutic efficacy of Listeria(at)-Mage-b vaccine in correlation with improved T-cell responses in blood of a triple-negative breast cancer model 4T1. Cancer Medicine. 2: 571-82. PMID 24156030 DOI: 10.1002/cam4.94  0.36
2013 Jeon H, Ohaegbulam KC, Abadi YM, Zang X. B7x and myeloid-derived suppressor cells in the tumor microenvironment: A tale of two cities. Oncoimmunology. 2: e24744. PMID 24073367 DOI: 10.4161/onci.24744  0.52
2013 Zhao R, Chinai JM, Buhl S, Scandiuzzi L, Ray A, Jeon H, Ohaegbulam KC, Ghosh K, Zhao A, Scharff MD, Zang X. HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function. Proceedings of the National Academy of Sciences of the United States of America. 110: 9879-84. PMID 23716685 DOI: 10.1073/pnas.1303524110  0.52
2013 Vigdorovich V, Ramagopal UA, Lázár-Molnár E, Sylvestre E, Lee JS, Hofmeyer KA, Zang X, Nathenson SG, Almo SC. Structure and T cell inhibition properties of B7 family member, B7-H3. Structure (London, England : 1993). 21: 707-17. PMID 23583036 DOI: 10.1016/j.str.2013.03.003  0.52
2013 Abadi YM, Jeon H, Ohaegbulam KC, Scandiuzzi L, Ghosh K, Hofmeyer KA, Lee JS, Ray A, Gravekamp C, Zang X. Host b7x promotes pulmonary metastasis of breast cancer. Journal of Immunology (Baltimore, Md. : 1950). 190: 3806-14. PMID 23455497 DOI: 10.4049/jimmunol.1202439  0.52
2012 Janakiram M, Abadi YM, Sparano JA, Zang X. T cell coinhibition and immunotherapy in human breast cancer. Discovery Medicine. 14: 229-36. PMID 23114578  0.52
2012 Lee JS, Scandiuzzi L, Ray A, Wei J, Hofmeyer KA, Abadi YM, Loke P, Lin J, Yuan J, Serreze DV, Allison JP, Zang X. B7x in the periphery abrogates pancreas-specific damage mediated by self-reactive CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 4165-74. PMID 22972920 DOI: 10.4049/jimmunol.1201241  0.52
2012 Hofmeyer KA, Scandiuzzi L, Ghosh K, Pirofski LA, Zang X. Tissue-expressed B7x affects the immune response to and outcome of lethal pulmonary infection. Journal of Immunology (Baltimore, Md. : 1950). 189: 3054-63. PMID 22855708 DOI: 10.4049/jimmunol.1200701  0.52
2011 Hofmeyer KA, Jeon H, Zang X. The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion. Journal of Biomedicine & Biotechnology. 2011: 451694. PMID 21960736 DOI: 10.1155/2011/451694  0.52
2011 Scandiuzzi L, Ghosh K, Zang X. T cell costimulation and coinhibition: genetics and disease. Discovery Medicine. 12: 119-28. PMID 21878189  0.52
2011 Barach YS, Lee JS, Zang X. T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics. Trends in Molecular Medicine. 17: 47-55. PMID 20971039 DOI: 10.1016/j.molmed.2010.09.006  0.36
2010 Scandiuzzi L, Beghdadi W, Daugas E, Abrink M, Tiwari N, Brochetta C, Claver J, Arouche N, Zang X, Pretolani M, Monteiro RC, Pejler G, Blank U. Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis. Journal of Immunology (Baltimore, Md. : 1950). 185: 624-33. PMID 20530261 DOI: 10.4049/jimmunol.0902129  0.36
2010 Zang X, Sullivan PS, Soslow RA, Waitz R, Reuter VE, Wilton A, Thaler HT, Arul M, Slovin SF, Wei J, Spriggs DR, Dupont J, Allison JP. Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 23: 1104-12. PMID 20495537 DOI: 10.1038/modpathol.2010.95  0.52
2008 Hofmeyer KA, Ray A, Zang X. The contrasting role of B7-H3. Proceedings of the National Academy of Sciences of the United States of America. 105: 10277-8. PMID 18650376 DOI: 10.1073/pnas.0805458105  0.52
2007 Zang X, Allison JP. The B7 family and cancer therapy: costimulation and coinhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5271-9. PMID 17875755 DOI: 10.1158/1078-0432.CCR-07-1030  0.52
2007 Cao E, Zang X, Ramagopal UA, Mukhopadhaya A, Fedorov A, Fedorov E, Zencheck WD, Lary JW, Cole JL, Deng H, Xiao H, Dilorenzo TP, Allison JP, Nathenson SG, Almo SC. T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface. Immunity. 26: 311-21. PMID 17363302 DOI: 10.1016/j.immuni.2007.01.016  0.52
2006 Zang X, Allison JP. To be or not to be B7. The Journal of Clinical Investigation. 116: 2590-3. PMID 17016555 DOI: 10.1172/JCI30103  0.52
2006 Zang X, Loke P, Kim J, Wojnoonski K, Kusdra L, Allison JP. A genetic library screen for signaling proteins that interact with phosphorylated T cell costimulatory receptors. Genomics. 88: 841-5. PMID 17014982 DOI: 10.1016/j.ygeno.2006.08.012  0.52
2005 Loke P, Zang X, Hsuan L, Waitz R, Locksley RM, Allen JE, Allison JP. Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection. Proceedings of the National Academy of Sciences of the United States of America. 102: 9872-7. PMID 15994233 DOI: 10.1073/pnas.0503961102  0.52
2003 Zang X, Loke P, Kim J, Murphy K, Waitz R, Allison JP. B7x: a widely expressed B7 family member that inhibits T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 100: 10388-92. PMID 12920180 DOI: 10.1073/pnas.1434299100  0.52
2002 Zang X, Taylor P, Wang JM, Meyer DJ, Scott AL, Walkinshaw MD, Maizels RM. Homologues of human macrophage migration inhibitory factor from a parasitic nematode. Gene cloning, protein activity, and crystal structure. The Journal of Biological Chemistry. 277: 44261-7. PMID 12221083 DOI: 10.1074/jbc.M204655200  0.52
2002 Emes R, Thompson F, Moore J, Zang X, Devaney E. Cloning and characterisation of mmc-1, a microfilarial-specific gene, from Brugia pahangi International Journal For Parasitology. 32: 415-424. PMID 11849638 DOI: 10.1016/S0020-7519(02)00003-6  0.52
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