H Earl Ruley - Publications

Microbiology and Immunology Vanderbilt University, Nashville, TN 
Microbiology Biology, Molecular Biology, Military Studies

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chung E, Choi Y, Park J, Nah W, Park J, Jung Y, Lee J, Lee H, Park S, Hwang S, Kim S, Lee J, Min D, Jo J, Kang S, ... ... Ruley HE, et al. Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein. Science Advances. 6: eaba1193. PMID 32494688 DOI: 10.1126/Sciadv.Aba1193  0.6
2014 Duong T, Kim J, Ruley HE, Jo D. Cell-permeable parkin proteins suppress Parkinson disease-associated phenotypes in cultured cells and animals. Plos One. 9: e102517. PMID 25019626 DOI: 10.1371/Journal.Pone.0102517  1
2013 Lim J, Duong T, Lee G, Seong BL, El-Rifai W, Ruley HE, Jo D. The effect of intracellular protein delivery on the anti-tumor activity of recombinant human endostatin. Biomaterials. 34: 6261-71. PMID 23714245 DOI: 10.1016/J.Biomaterials.2013.05.011  1
2013 Lim J, Duong T, Do N, Do P, Kim J, Kim H, El-Rifai W, Ruley HE, Jo D. Antitumor activity of cell-permeable RUNX3 protein in gastric cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 680-90. PMID 23230322 DOI: 10.1158/1078-0432.Ccr-12-2692  0.6
2012 Lim J, Kim J, Duong T, Lee G, Kim J, Yoon J, Kim J, Kim H, Ruley HE, El-Rifai W, Jo D. Antitumor activity of cell-permeable p18(INK4c) with enhanced membrane and tissue penetration. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1540-9. PMID 22617107 DOI: 10.1038/Mt.2012.102  1
2012 Lin Q, Liu Y, Moore DJ, Elizer SK, Veach RA, Hawiger J, Ruley HE. Cutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 188: 2493-7. PMID 22323537 DOI: 10.4049/Jimmunol.1101502  1
2011 Lim J, Jang G, Kang S, Lee G, Nga do TT, Phuong do TL, Kim H, El-Rifai W, Ruley HE, Jo D. Cell-permeable NM23 blocks the maintenance and progression of established pulmonary metastasis. Cancer Research. 71: 7216-25. PMID 21987726 DOI: 10.1158/0008-5472.Can-11-2015  1
2010 Jeon D, Kim S, Chetana M, Jo D, Ruley HE, Lin SY, Rabah D, Kinet JP, Shin HS. Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC. Nature Neuroscience. 13: 482-8. PMID 20190743 DOI: 10.1038/Nn.2504  1
2008 Osipovich AB, Jennings JL, Lin Q, Link AJ, Ruley HE. Dyggve-Melchior-Clausen syndrome: chondrodysplasia resulting from defects in intracellular vesicle traffic. Proceedings of the National Academy of Sciences of the United States of America. 105: 16171-6. PMID 18852472 DOI: 10.1073/Pnas.0804259105  1
2008 Cao S, Carlesso G, Osipovich AB, Llanes J, Lin Q, Hoek KL, Khan WN, Ruley HE. Subunit 1 of the prefoldin chaperone complex is required for lymphocyte development and function. Journal of Immunology (Baltimore, Md. : 1950). 181: 476-84. PMID 18566413 DOI: 10.4049/Jimmunol.181.1.476  1
2006 Lin Q, Donahue SL, Ruley HE. Genome maintenance and mutagenesis in embryonic stem cells. Cell Cycle (Georgetown, Tex.). 5: 2710-4. PMID 17172854 DOI: 10.4161/Cc.5.23.3517  1
2006 Lin Q, Donahue SL, Moore-Jarrett T, Cao S, Osipovich AB, Ruley HE. Mutagenesis of diploid mammalian genes by gene entrapment. Nucleic Acids Research. 34: e139. PMID 17062627 DOI: 10.1093/Nar/Gkl728  1
2006 Donahue SL, Lin Q, Cao S, Ruley HE. Carcinogens induce genome-wide loss of heterozygosity in normal stem cells without persistent chromosomal instability. Proceedings of the National Academy of Sciences of the United States of America. 103: 11642-6. PMID 16868089 DOI: 10.1073/Pnas.0510741103  1
2006 Rubin DH, Ruley HE. Cellular genetics of host susceptibility and resistance to virus infection. Critical Reviews in Eukaryotic Gene Expression. 16: 155-70. PMID 16749895 DOI: 10.1615/Critreveukargeneexpr.V16.I2.40  1
2005 Roshon MJ, Ruley HE. Hypomorphic mutation in hnRNP U results in post-implantation lethality. Transgenic Research. 14: 179-92. PMID 16022389 DOI: 10.1007/S11248-004-8147-8  1
2005 Osipovich AB, Singh A, Ruley HE. Post-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapment. Genome Research. 15: 428-35. PMID 15741512 DOI: 10.1101/Gr.3258105  1
2005 Scott RE, White-Grindley E, Ruley HE, Chesler EJ, Williams RW. P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA. Journal of Cellular Physiology. 204: 99-105. PMID 15617101 DOI: 10.1002/Jcp.20263  1
2004 Organ EL, Sheng J, Ruley HE, Rubin DH. Discovery of mammalian genes that participate in virus infection. Bmc Cell Biology. 5: 41. PMID 15522117 DOI: 10.1186/1471-2121-5-41  1
2004 Lin Q, Jo D, Gebre-Amlak KD, Ruley HE. Enhanced cell-permeant Cre protein for site-specific recombination in cultured cells. Bmc Biotechnology. 4: 25. PMID 15500682 DOI: 10.1186/1472-6750-4-25  1
2004 Sheng J, Organ EL, Hao C, Wells KS, Ruley HE, Rubin DH. Mutations in the IGF-II pathway that confer resistance to lytic reovirus infection. Bmc Cell Biology. 5: 32. PMID 15333144 DOI: 10.1186/1471-2121-5-32  1
2004 Osipovich AB, White-Grindley EK, Hicks GG, Roshon MJ, Shaffer C, Moore JH, Ruley HE. Activation of cryptic 3' splice sites within introns of cellular genes following gene entrapment. Nucleic Acids Research. 32: 2912-24. PMID 15155860 DOI: 10.1093/Nar/Gkh604  1
2003 Cao S, Bendall H, Hicks GG, Nashabi A, Sakano H, Shinkai Y, Gariglio M, Oltz EM, Ruley HE. The high-mobility-group box protein SSRP1/T160 is essential for cell viability in day 3.5 mouse embryos. Molecular and Cellular Biology. 23: 5301-7. PMID 12861016 DOI: 10.1128/Mcb.23.15.5301-5307.2003  1
2003 Jo D, Lin Q, Nashabi A, Mays DJ, Unutmaz D, Pietenpol JA, Ruley HE. Cell cycle-dependent transduction of cell-permeant Cre recombinase proteins. Journal of Cellular Biochemistry. 89: 674-87. PMID 12858334 DOI: 10.1002/Jcb.10542  1
2003 Roshon M, DeGregori JV, Ruley HE. Gene trap mutagenesis of hnRNP A2/B1: a cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular gene. Bmc Genomics. 4: 2. PMID 12546712 DOI: 10.1186/1471-2164-4-2  1
2002 Pawlak MR, Banik-Maiti S, Pietenpol JA, Ruley HE. Protein arginine methyltransferase I: substrate specificity and role in hnRNP assembly. Journal of Cellular Biochemistry. 87: 394-407. PMID 12397599 DOI: 10.1002/Jcb.10307  1
2001 White EK, Moore-Jarrett T, Ruley HE. PUM2, a novel murine puf protein, and its consensus RNA-binding site. Rna (New York, N.Y.). 7: 1855-66. PMID 11780640  1
2001 Jo D, Nashabi A, Doxsee C, Lin Q, Unutmaz D, Chen J, Ruley HE. Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nature Biotechnology. 19: 929-33. PMID 11581657 DOI: 10.1038/Nbt1001-929  1
2001 Ruley HE. Functional genomics of the murine immune system. Immunologic Research. 23: 289-99. PMID 11444394 DOI: 10.1385/Ir:23:2-3:289  1
2000 Peck SR, Ruley HE. Ly108: a new member of the mouse CD2 family of cell surface proteins. Immunogenetics. 52: 63-72. PMID 11132158 DOI: 10.1007/S002510000252  1
2000 Pawlak MR, Scherer CA, Chen J, Roshon MJ, Ruley HE. Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable. Molecular and Cellular Biology. 20: 4859-69. PMID 10848611 DOI: 10.1128/Mcb.20.13.4859-4869.2000  1
2000 Williamson DJ, Banik-Maiti S, DeGregori J, Ruley HE. hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability. Molecular and Cellular Biology. 20: 4094-105. PMID 10805751 DOI: 10.1128/Mcb.20.11.4094-4105.2000  1
2000 Hicks GG, Singh N, Nashabi A, Mai S, Bozek G, Klewes L, Arapovic D, White EK, Koury MJ, Oltz EM, Van Kaer L, Ruley HE. Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death. Nature Genetics. 24: 175-9. PMID 10655065 DOI: 10.1038/72842  1
1998 Kelley LL, Hicks GG, Hsieh FF, Prasher JM, Green WF, Miller MD, Eide EJ, Ruley HE. Endogenous p53 regulation and function in early stage Friend virus-induced tumor progression differs from that following DNA damage. Oncogene. 17: 1119-30. PMID 9764822 DOI: 10.1038/sj.onc.1202037  1
1998 Chen J, Ruley HE. An enhancer element in the EphA2 (Eck) gene sufficient for rhombomere-specific expression is activated by HOXA1 and HOXB1 homeobox proteins. The Journal of Biological Chemistry. 273: 24670-5. PMID 9733765 DOI: 10.1074/jbc.273.38.24670  1
1997 Hicks GG, Shi EG, Li XM, Li CH, Pawlak M, Ruley HE. Functional genomics in mice by tagged sequence mutagenesis. Nature Genetics. 16: 338-44. PMID 9241269 DOI: 10.1038/ng0897-338  1
1996 Scherer CA, Chen J, Nachabeh A, Hopkins N, Ruley HE. Transcriptional specificity of the pluripotent embryonic stem cell. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 7: 1393-401. PMID 8891343  0.36
1996 Ruley HE. p53 and response to chemotherapy and radiotherapy. Important Advances in Oncology. 37-56. PMID 8791127  1
1996 Chen J, Nachabah A, Scherer C, Ganju P, Reith A, Bronson R, Ruley HE. Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion. Oncogene. 12: 979-88. PMID 8649815  1
1996 Martin WD, Hicks GG, Mendiratta SK, Leva HI, Ruley HE, Van Kaer L. H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection. Cell. 84: 543-50. PMID 8598041 DOI: 10.1016/S0092-8674(00)81030-2  1
1995 Hicks GG, Shi EG, Chen J, Roshon M, Williamson D, Scherer C, Ruley HE. Retrovirus gene traps. Methods in Enzymology. 254: 263-75. PMID 8531691 DOI: 10.1016/0076-6879(95)54019-9  1
1995 Bushel P, Kim JH, Chang W, Catino JJ, Ruley HE, Kumar CC. Two serum response elements mediate transcriptional repression of human smooth muscle alpha-actin promoter in ras-transformed cells. Oncogene. 10: 1361-70. PMID 7731687  1
1994 DeGregori J, Russ A, Von Melchner H, Rayburn H, Priyaranjan P, Jenkins NA, Copeland NG, Ruley HE. A murine homolog of the yeast RNA1 gene is required for postimplantation development Genes and Development. 8: 265-276. PMID 8314081 DOI: 10.1101/Gad.8.3.265  1
1994 Kelley LL, Green WF, Hicks GG, Bondurant MC, Koury MJ, Ruley HE. Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53. Molecular and Cellular Biology. 14: 4183-92. PMID 8196656  1
1994 Lowe SW, Jacks T, Housman DE, Ruley HE. Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 2026-30. PMID 8134344 DOI: 10.1073/Pnas.91.6.2026  1
1994 Hubbard SC, Walls L, Ruley HE, Muchmore EA. Generation of Chinese hamster ovary cell glycosylation mutants by retroviral insertional mutagenesis. Integration into a discrete locus generates mutants expressing high levels of N-glycolylneuraminic acid. The Journal of Biological Chemistry. 269: 3717-24. PMID 8106417  1
1994 Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE, Jacks T. p53 status and the efficacy of cancer therapy in vivo. Science (New York, N.Y.). 266: 807-10. PMID 7973635 DOI: 10.1126/Science.7973635  1
1994 Lowe SW, Bodis S, Bardeesy N, McClatchey A, Remington L, Ruley HE, Fisher DE, Jacks T, Pelletier J, Housman DE. Apoptosis and the prognostic significance of p53 mutation. Cold Spring Harbor Symposia On Quantitative Biology. 59: 419-26. PMID 7587096  1
1993 Chang W, Hubbard SC, Friedel C, Ruley HE. Enrichment of insertional mutants following retrovirus gene trap selection. Virology. 193: 737-47. PMID 8460482 DOI: 10.1006/viro.1993.1182  1
1993 Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 74: 957-67. PMID 8402885 DOI: 10.1016/0092-8674(93)90719-7  1
1992 Reddy S, Rayburn H, von Melchner H, Ruley HE. Fluorescence-activated sorting of totipotent embryonic stem cells expressing developmentally regulated lacZ fusion genes. Proceedings of the National Academy of Sciences of the United States of America. 89: 6721-5. PMID 1495960 DOI: 10.1073/pnas.89.15.6721  1
1991 Ravid K, Beeler DL, Rabin MS, Ruley HE, Rosenberg RD. Selective targeting of gene products with the megakaryocyte platelet factor 4 promoter. Proceedings of the National Academy of Sciences of the United States of America. 88: 1521-5. PMID 1899930 DOI: 10.1073/Pnas.88.4.1521  1
1991 Ragozzino MM, Kuo A, DeGregori J, Kohl N, Ruley HE. Mechanisms of oncogene cooperation: activation and inactivation of a growth antagonist. Environmental Health Perspectives. 93: 97-103. PMID 1837777 DOI: 10.1289/Ehp.919397  1
1991 Reddy S, DeGregori JV, von Melchner H, Ruley HE. Retrovirus promoter-trap vector to induce lacZ gene fusions in mammalian cells. Journal of Virology. 65: 1507-15. PMID 1704929 DOI: 10.1128/Jvi.65.3.1507-1515.1991  1
1990 von Melchner H, Reddy S, Ruley HE. Isolation of cellular promoters by using a retrovirus promoter trap. Proceedings of the National Academy of Sciences of the United States of America. 87: 3733-7. PMID 2339116 DOI: 10.1073/pnas.87.10.3733  1
1990 Reddy S, Ozgur K, Lu M, Chang W, Mohan SR, Kumar CC, Ruley HE. Structure of the human smooth muscle alpha-actin gene. Analysis of a cDNA and 5' upstream region. The Journal of Biological Chemistry. 265: 1683-7. PMID 2295650  1
1990 von Melchner H, Ruley HE. Retroviruses as genetic tools to isolate transcriptionally active chromosomal regions. Environmental Health Perspectives. 88: 141-8. PMID 2272309  1
1990 Ruley HE. Transforming collaborations between ras and nuclear oncogenes. Cancer Cells (Cold Spring Harbor, N.Y. : 1989). 2: 258-68. PMID 2223387  1
1989 von Melchner H, Ruley HE. Identification of cellular promoters by using a retrovirus promoter trap. Journal of Virology. 63: 3227-33. PMID 2545900  1
1988 Whyte P, Ruley HE, Harlow E. Two regions of the adenovirus early region 1A proteins are required for transformation. Journal of Virology. 62: 257-65. PMID 2960834 DOI: 10.1128/Jvi.62.1.257-265.1988  1
1988 Ruley HE, Chaudry F, Read M, Lania L, Fried M. The structure and function of the integrated polyoma virus DNA in 82-rat and 53-rat transformed cells. The Journal of General Virology. 69: 197-207. PMID 2826666 DOI: 10.1099/0022-1317-69-1-197  1
1987 Maruyama K, Schiavi SC, Huse W, Johnson GL, Ruley HE. myc and E1A oncogenes alter the responses of PC12 cells to nerve growth factor and block differentiation. Oncogene. 1: 361-7. PMID 2838784  1
1987 Kohl NE, Ruley HE. Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes. Oncogene. 2: 41-8. PMID 2830582  1
1987 Frisch SM, Ruley HE. Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone. The Journal of Biological Chemistry. 262: 16300-4. PMID 2824488  1
1986 Franza BR, Maruyama K, Garrels JI, Ruley HE. In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell. 44: 409-18. PMID 3510745 DOI: 10.1016/0092-8674(86)90462-9  1
1986 Zerler B, Moran B, Maruyama K, Moomaw J, Grodzicker T, Ruley HE. Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells. Molecular and Cellular Biology. 6: 887-99. PMID 3022137  1
1986 Cook JL, Walker TA, Lewis AM, Ruley HE, Graham FL, Pilder SH. Expression of the adenovirus E1A oncogene during cell transformation is sufficient to induce susceptibility to lysis by host inflammatory cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 6965-9. PMID 2944117 DOI: 10.1073/Pnas.83.18.6965  1
1983 Ruley HE. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature. 304: 602-6. PMID 6308473 DOI: 10.1038/304602a0  1
1983 Ruley HE, Fried M. Clustered illegitimate recombination events in mammalian cells involving very short sequence homologies. Nature. 304: 181-4. PMID 6306477 DOI: 10.1038/304181a0  1
1983 Ruley HE, Fried M. Sequence repeats in a polyoma virus DNA region important for gene expression. Journal of Virology. 47: 233-7. PMID 6306275 DOI: 10.1128/JVI.47.1.233-237.1983  1
1982 Anderson LM, Ruley HE, Bott KF. Isolation of an autonomously replicating DNA fragment from the region of defective bacteriophage PBSX of Bacillus subtilis. Journal of Bacteriology. 150: 1280-6. PMID 6804442  1
1982 Hayday A, Ruley HE, Fried M. Structural and biological analysis of integrated polyoma virus DNA and its adjacent host sequences cloned from transformed rat cells. Journal of Virology. 44: 67-77. PMID 6292505  1
1982 Ruley HE, Lania L, Chaudry F, Fried M. Use of a cellular polyadenylation signal by viral transcripts in polyoma virus transformed cells. Nucleic Acids Research. 10: 4515-24. PMID 6290990 DOI: 10.1093/Nar/10.15.4515  1
1982 Ruley HE, Lania L, Chaudry F, Fried M. Use of a cellular potyadenylation signal by viral transcripts in polyoma virus transformed cells Nucleic Acids Research. 10: 4515-4524. DOI: 10.1093/nar/10.15.4515  1
Show low-probability matches.