Florence Hofman - Publications

Affiliations: 
Pathobiology University of Southern California, Los Angeles, CA, United States 
Area:
Pathology, Microbiology Biology

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Marín-Ramos NI, Pérez-Hernández M, Tam A, Swenson SD, Cho HY, Thein TZ, Hofman FM, Chen TC. Inhibition of motility by NEO100 through the calpain-1/RhoA pathway. Journal of Neurosurgery. 1-12. PMID 31419797 DOI: 10.3171/2019.5.JNS19798  0.48
2019 Wang W, Swenson S, Cho HY, Hofman FM, Schönthal AH, Chen TC. Efficient brain targeting and therapeutic intracranial activity of bortezomib through intranasal co-delivery with NEO100 in rodent glioblastoma models. Journal of Neurosurgery. 1-9. PMID 30875688 DOI: 10.3171/2018.11.JNS181161  0.56
2019 Peng L, Fu J, Wang W, Hofman FM, Chen TC, Chen L. Distribution of cancer stem cells in two human brain gliomas. Oncology Letters. 17: 2123-2130. PMID 30719107 DOI: 10.3892/ol.2018.9824  0.56
2019 Cho HY, Thein TZ, Wang W, Swenson SD, Fayngor RA, Ou M, Marín-Ramos NI, Schönthal AH, Hofman FM, Chen TC. The Rolipram-Perillyl Alcohol Conjugate (NEO214) Is A Mediator Of Cell Death Through The Death Receptor Pathway. Molecular Cancer Therapeutics. PMID 30647121 DOI: 10.1158/1535-7163.MCT-18-0465  0.56
2018 Swenson S, Silva-Hirschberg C, Wang W, Singh A, Hofman FM, Chen KL, Schönthal AH, Chen TC. NEO412: A temozolomide analog with transdermal activity in melanoma and . Oncotarget. 9: 37026-37041. PMID 30651933 DOI: 10.18632/oncotarget.26443  0.56
2018 Marín-Ramos NI, Jhaveri N, Thein TZ, Fayngor RA, Chen TC, Hofman FM. NEO212, a conjugate of temozolomide and perillyl alcohol, blocks the endothelial-to-mesenchymal transition in tumor-associated brain endothelial cells in glioblastoma. Cancer Letters. PMID 30392789 DOI: 10.1016/j.canlet.2018.10.034  0.56
2018 Chen TC, Chan N, Minea RO, Hartman H, Hofman FM, Schönthal AH. Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treatment with Temozolomide In Vitro and In Vivo. Cancers. 10. PMID 30274152 DOI: 10.3390/cancers10100362  0.48
2018 Bota DA, Chung J, Dandekar M, Carrillo JA, Kong XT, Fu BD, Hsu FP, Schönthal AH, Hofman FM, Chen TC, Zidovetzki R, Pretto C, Strik A, Schijns VE, Stathopoulos A. Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma: interim results and correlations with CD4 T-lymphocyte counts. Cns Oncology. PMID 30157683 DOI: 10.2217/cns-2018-0009  0.48
2018 Schijns VEJC, Pretto C, Strik AM, Gloudemans-Rijkers R, Deviller L, Pierre D, Chung J, Dandekar M, Carrillo JA, Kong XT, Fu BD, Hsu FPK, Hofman FM, Chen TC, Zidovetzki R, et al. Therapeutic Immunization against Glioblastoma. International Journal of Molecular Sciences. 19. PMID 30150597 DOI: 10.3390/ijms19092540  0.48
2018 Marín-Ramos NI, Hofman FM, Chen TC. NEO212: sub-cytotoxic doses capable of inhibiting glioma stem cell invasion. Oncoscience. 5: 148-149. PMID 30035171 DOI: 10.18632/oncoscience.429  0.48
2018 Marín-Ramos NI, Thein TZ, Cho HY, Swenson SD, Wang W, Schönthal AH, Chen TC, Hofman FM. NEO212 Inhibits Migration and Invasion of Glioma Stem Cells. Molecular Cancer Therapeutics. PMID 29440289 DOI: 10.1158/1535-7163.MCT-17-0591  0.56
2018 Chen TC, Chan N, Labib S, Yu J, Cho HY, Hofman FM, Schönthal AH. Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram. International Journal of Molecular Sciences. 19. PMID 29342125 DOI: 10.3390/ijms19010277  0.48
2017 Chen TC, Yu J, Nigjeh EN, Wang W, Myint PT, Zandi E, Hofman FM, Schönthal AH. A Perillyl Alcohol-Conjugated Analog of 3-Bromopyruvate Without Cellular Uptake Dependency on Monocarboxylate Transporter 1 and With Activity in 3-BP-Resistant Tumor Cells. Cancer Letters. PMID 28450161 DOI: 10.1016/j.canlet.2017.04.015  0.56
2017 Wang W, Cho HY, Rosenstein-Sisson R, Marín Ramos NI, Price R, Hurth K, Schönthal AH, Hofman FM, Chen TC. Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model. Journal of Neurosurgery. 1-6. PMID 28409734 DOI: 10.3171/2016.11.JNS161212  0.56
2016 Rosa AI, Grade S, Santos SD, Bernardino L, Chen TC, Relvas J, Hofman FM, Agasse F. Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and α6β1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties. Frontiers in Cellular Neuroscience. 10: 284. PMID 28018177 DOI: 10.3389/fncel.2016.00284  0.48
2016 Kushal S, Wang W, Vaikari VP, Kota R, Chen K, Yeh TS, Jhaveri N, Groshen SL, Olenyuk BZ, Chen TC, Hofman FM, Shih JC. Monoamine oxidase A (MAO A) inhibitors decrease glioma progression. Oncotarget. PMID 26871599 DOI: 10.18632/oncotarget.7283  0.56
2016 Dong H, Zou M, Bhatia A, Jayaprakash P, Hofman F, Ying Q, Chen M, Woodley DT, Li W. Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment. Scientific Reports. 6: 20605. PMID 26846992 DOI: 10.1038/srep20605  0.56
2015 Jhaveri N, Agasse F, Armstrong D, Peng L, Commins D, Wang W, Rosenstein-Sisson R, Vaikari VP, Santiago SV, Santos T, Chen L, Schönthal AH, Chen TC, Hofman FM. A novel drug conjugate targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells. Cancer Letters. PMID 26683773 DOI: 10.1016/j.canlet.2015.11.040  0.56
2015 Hu CJ, Fang RH, Wang KC, Luk BT, Thamphiwatana S, Dehaini D, Nguyen P, Angsantikul P, Wen CH, Kroll AV, Carpenter C, Ramesh M, Qu V, Patel SH, Zhu J, ... ... Hofman FM, et al. Nanoparticle biointerfacing by platelet membrane cloaking. Nature. PMID 26374997 DOI: 10.1038/nature15373  0.56
2015 Chen TC, Cho HY, Wang W, Wetzel SJ, Singh A, Nguyen J, Hofman FM, Schönthal AH. Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo. Journal of Biomedical Science. 22: 71. PMID 26282951 DOI: 10.1186/s12929-015-0175-6  0.56
2015 Schijns VE, Pretto C, Devillers L, Pierre D, Hofman FM, Chen TC, Mespouille P, Hantos P, Glorieux P, Bota DA, Stathopoulos A. First clinical results of a personalized immunotherapeutic vaccine against recurrent, incompletely resected, treatment-resistant glioblastoma multiforme (GBM) tumors, based on combined allo- and auto-immune tumor reactivity. Vaccine. 33: 2690-6. PMID 25865468 DOI: 10.1016/j.vaccine.2015.03.095  0.56
2015 Bota DA, Alexandru-Abrams D, Pretto C, Hofman FM, Chen TC, Fu B, Carrillo JA, Schijns VE, Stathopoulos A. Use of ERC-1671 Vaccine in a Patient with Recurrent Glioblastoma Multiforme after Progression during Bevacizumab Therapy: First Published Report. The Permanente Journal. 19: 41-6. PMID 25785641 DOI: 10.7812/TPP/14-042  0.48
2015 Wang W, Sivakumar W, Torres S, Jhaveri N, Vaikari VP, Gong A, Howard A, Golden EB, Louie SG, Schönthal AH, Hofman FM, Chen TC. Effects of convection-enhanced delivery of bevacizumab on survival of glioma-bearing animals. Neurosurgical Focus. 38: E8. PMID 25727230 DOI: 10.3171/2015.1.FOCUS14743  0.56
2015 Golden EB, Cho HY, Hofman FM, Louie SG, Schönthal AH, Chen TC. Quinoline-based antimalarial drugs: a novel class of autophagy inhibitors. Neurosurgical Focus. 38: E12. PMID 25727221 DOI: 10.3171/2014.12.FOCUS14748  0.56
2015 Chen TC, Cho HY, Wang W, Nguyen J, Jhaveri N, Rosenstein-Sisson R, Hofman FM, Schönthal AH. A novel temozolomide analog, NEO212, with enhanced activity against MGMT-positive melanoma in vitro and in vivo. Cancer Letters. 358: 144-51. PMID 25524552 DOI: 10.1016/j.canlet.2014.12.021  0.56
2015 Huang TT, Parab S, Burnett R, Diago O, Ostertag D, Hofman FM, Espinoza FL, Martin B, Ibañez CE, Kasahara N, Gruber HE, Pertschuk D, Jolly DJ, Robbins JM. Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model. Human Gene Therapy. 26: 82-93. PMID 25419577 DOI: 10.1089/hum.2014.100  0.56
2014 Jhaveri N, Chen TC, Hofman FM. Tumor vasculature and glioma stem cells: Contributions to glioma progression. Cancer Letters. PMID 25527451 DOI: 10.1016/j.canlet.2014.12.028  0.56
2014 Golden EB, Cho HY, Jahanian A, Hofman FM, Louie SG, Schönthal AH, Chen TC. Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy. Neurosurgical Focus. 37: E12. PMID 25434381 DOI: 10.3171/2014.9.FOCUS14504  0.56
2014 Santos T, Fang X, Chen MT, Wang W, Ferreira R, Jhaveri N, Gundersen M, Zhou C, Pagnini P, Hofman FM, Chen TC. Sequential administration of carbon nanotubes and near-infrared radiation for the treatment of gliomas. Frontiers in Oncology. 4: 180. PMID 25077069 DOI: 10.3389/fonc.2014.00180  0.56
2014 Cho HY, Wang W, Jhaveri N, Lee DJ, Sharma N, Dubeau L, Schönthal AH, Hofman FM, Chen TC. NEO212, temozolomide conjugated to perillyl alcohol, is a novel drug for effective treatment of a broad range of temozolomide-resistant gliomas. Molecular Cancer Therapeutics. 13: 2004-17. PMID 24994771 DOI: 10.1158/1535-7163.MCT-13-0964  0.56
2014 Ferreira R, Santos T, Amar A, Gong A, Chen TC, Tahara SM, Giannotta SL, Hofman FM. Argonaute-2 promotes miR-18a entry in human brain endothelial cells. Journal of the American Heart Association. 3: e000968. PMID 24837588 DOI: 10.1161/JAHA.114.000968  0.56
2014 Chen TC, Cho HY, Wang W, Barath M, Sharma N, Hofman FM, Schönthal AH. A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo. Molecular Cancer Therapeutics. 13: 1181-93. PMID 24623736 DOI: 10.1158/1535-7163.MCT-13-0882  0.56
2014 Peterson A, Bansal A, Hofman F, Chen TC, Zada G. A systematic review of inhaled intranasal therapy for central nervous system neoplasms: an emerging therapeutic option. Journal of Neuro-Oncology. 116: 437-46. PMID 24398618 DOI: 10.1007/s11060-013-1346-5  0.48
2014 Ferreira R, Santos T, Amar A, Tahara SM, Chen TC, Giannotta SL, Hofman FM. MicroRNA-18a improves human cerebral arteriovenous malformation endothelial cell function. Stroke; a Journal of Cerebral Circulation. 45: 293-7. PMID 24203843 DOI: 10.1161/STROKEAHA.113.003578  0.56
2013 Hofman FM, Taylor CR. Immunohistochemistry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. 103: Unit 21.4.. PMID 24510546 DOI: 10.1002/0471142735.im2104s103  0.56
2013 Thomas S, Sharma N, Gonzalez R, Pao PW, Hofman FM, Chen TC, Louie SG, Pirrung MC, Schönthal AH. Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I. Plos One. 8: e65695. PMID 23755268 DOI: 10.1371/journal.pone.0065695  0.56
2012 Stathopoulos A, Pretto C, Devillers L, Pierre D, Hofman FM, Epstein AL, Farghadani H, Kruse CA, Jadus MR, Chen TC, Schijns VE. Exploring the Therapeutic Efficacy of Glioma Vaccines Based on Allo- and Syngeneic Antigens and Distinct Immunological Costimulation Activators. Journal of Clinical & Cellular Immunology. 004. PMID 24955288 DOI: 10.4172/2155-9899.S5-004  0.48
2012 Cho HY, Wang W, Jhaveri N, Torres S, Tseng J, Leong MN, Lee DJ, Goldkorn A, Xu T, Petasis NA, Louie SG, Schönthal AH, Hofman FM, Chen TC. Perillyl alcohol for the treatment of temozolomide-resistant gliomas. Molecular Cancer Therapeutics. 11: 2462-72. PMID 22933703 DOI: 10.1158/1535-7163.MCT-12-0321  0.56
2012 Sharma N, Thomas S, Golden EB, Hofman FM, Chen TC, Petasis NA, Schönthal AH, Louie SG. Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent. Cancer Letters. 326: 143-54. PMID 22863539 DOI: 10.1016/j.canlet.2012.07.029  0.56
2012 Stathopoulos A, Pretto C, Devillers L, Pierre D, Hofman FM, Kruse C, Jadus M, Chen TC, Schijns VE. Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation. Oncoimmunology. 1: 298-305. PMID 22737605 DOI: 10.4161/onci.19068  0.56
2012 Thomas S, Sharma N, Golden EB, Cho H, Agarwal P, Gaffney KJ, Petasis NA, Chen TC, Hofman FM, Louie SG, Schönthal AH. Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors. Cancer Letters. 325: 63-71. PMID 22664238 DOI: 10.1016/j.canlet.2012.05.030  0.56
2011 Jhaveri N, Cho H, Torres S, Wang W, Schönthal AH, Petasis NA, Louie SG, Hofman FM, Chen TC. Noscapine inhibits tumor growth in TMZ-resistant gliomas. Cancer Letters. 312: 245-52. PMID 21925789 DOI: 10.1016/j.canlet.2011.08.015  0.56
2011 Schönthal AH, Chen TC, Hofman FM, Louie SG, Petasis NA. Preclinical development of novel anti-glioma drugs targeting the endoplasmic reticulum stress response. Current Pharmaceutical Design. 17: 2428-38. PMID 21827419 DOI: 10.2174/138161211797249242  0.56
2011 Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, Jhaveri N, Zhu G, Ye R, Liu Z, Bruhn KW, Craft N, Groshen S, Hofman FM, Lee AS. A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis. Cancer Research. 71: 2848-57. PMID 21467168 DOI: 10.1158/0008-5472.CAN-10-3151  0.56
2011 Stapleton CJ, Armstrong DL, Zidovetzki R, Liu CY, Giannotta SL, Hofman FM. Thrombospondin-1 modulates the angiogenic phenotype of human cerebral arteriovenous malformation endothelial cells. Neurosurgery. 68: 1342-53; discussion . PMID 21307796 DOI: 10.1227/NEU.0b013e31820c0a68  0.4
2011 Chen TC, Wang W, Golden EB, Thomas S, Sivakumar W, Hofman FM, Louie SG, Schönthal AH. Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models. Cancer Letters. 302: 100-8. PMID 21257259 DOI: 10.1016/j.canlet.2010.11.008  0.56
2011 Wang W, Ghandi A, Liebes L, Louie SG, Hofman FM, Schönthal AH, Chen TC. Effective conversion of irinotecan to SN-38 after intratumoral drug delivery to an intracranial murine glioma model in vivo. Laboratory investigation. Journal of Neurosurgery. 114: 689-94. PMID 20415520 DOI: 10.3171/2010.2.JNS09719  0.56
2010 Virrey JJ, Liu Z, Cho HY, Kardosh A, Golden EB, Louie SG, Gaffney KJ, Petasis NA, Schönthal AH, Chen TC, Hofman FM. Antiangiogenic activities of 2,5-dimethyl-celecoxib on the tumor vasculature. Molecular Cancer Therapeutics. 9: 631-41. PMID 20197398 DOI: 10.1158/1535-7163.MCT-09-0652  0.56
2009 Virrey JJ, Golden EB, Sivakumar W, Wang W, Pen L, Schönthal AH, Hofman FM, Chen TC. Glioma-associated endothelial cells are chemoresistant to temozolomide. Journal of Neuro-Oncology. 95: 13-22. PMID 19381445 DOI: 10.1007/s11060-009-9891-7  0.56
2009 Cho HY, Thomas S, Golden EB, Gaffney KJ, Hofman FM, Chen TC, Louie SG, Petasis NA, Schönthal AH. Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stress. Cancer Letters. 282: 87-97. PMID 19345476 DOI: 10.1016/j.canlet.2009.03.007  0.56
2009 Zandian M, Belisle R, Mott KR, Nusinowitz S, Hofman FM, Ghiasi H. Optic neuritis in different strains of mice by a recombinant HSV-1 expressing murine interleukin-2. Investigative Ophthalmology & Visual Science. 50: 3275-82. PMID 19234357 DOI: 10.1167/iovs.08-3211  0.56
2009 Jabbour MN, Elder JB, Samuelson CG, Khashabi S, Hofman FM, Giannotta SL, Liu CY. Aberrant angiogenic characteristics of human brain arteriovenous malformation endothelial cells. Neurosurgery. 64: 139-46; discussion 1. PMID 19145162 DOI: 10.1227/01.NEU.0000334417.56742.24  0.4
2008 Virrey JJ, Dong D, Stiles C, Patterson JB, Pen L, Ni M, Schönthal AH, Chen TC, Hofman FM, Lee AS. Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells. Molecular Cancer Research : McR. 6: 1268-75. PMID 18708359 DOI: 10.1158/1541-7786.MCR-08-0060  0.56
2008 Virrey JJ, Guan S, Li W, Schönthal AH, Chen TC, Hofman FM. Increased survivin expression confers chemoresistance to tumor-associated endothelial cells. The American Journal of Pathology. 173: 575-85. PMID 18599610 DOI: 10.2353/ajpath.2008.071079  0.56
2008 Kardosh A, Golden EB, Pyrko P, Uddin J, Hofman FM, Chen TC, Louie SG, Petasis NA, Schönthal AH. Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib. Cancer Research. 68: 843-51. PMID 18245486 DOI: 10.1158/0008-5472.CAN-07-5555  0.56
2008 Schönthal AH, Chen TC, Hofman FM, Louie SG, Petasis NA. Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs. Expert Opinion On Investigational Drugs. 17: 197-208. PMID 18230053 DOI: 10.1517/13543784.17.2.197  0.56
2008 Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS. Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Research. 68: 498-505. PMID 18199545 DOI: 10.1158/0008-5472.CAN-07-2950  0.56
2007 Pyrko P, Schönthal AH, Hofman FM, Chen TC, Lee AS. The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Research. 67: 9809-16. PMID 17942911 DOI: 10.1158/0008-5472.CAN-07-0625  0.48
2007 Kardosh A, Soriano N, Pyrko P, Liu YT, Jabbour M, Hofman FM, Schönthal AH. Reduced survivin expression and tumor cell survival during chronic hypoxia and further cytotoxic enhancement by the cyclooxygenase-2 inhibitor celecoxib. Journal of Biomedical Science. 14: 647-62. PMID 17440835 DOI: 10.1007/s11373-007-9173-3  0.56
2007 Gupta V, Su YS, Samuelson CG, Liebes LF, Chamberlain MC, Hofman FM, Schönthal AH, Chen TC. Irinotecan: a potential new chemotherapeutic agent for atypical or malignant meningiomas. Journal of Neurosurgery. 106: 455-62. PMID 17367069 DOI: 10.3171/jns.2007.106.3.455  0.48
2007 Charalambous C, Virrey J, Kardosh A, Jabbour MN, Qazi-Abdullah L, Pen L, Zidovetzki R, Schönthal AH, Chen TC, Hofman FM. Glioma-associated endothelial cells show evidence of replicative senescence. Experimental Cell Research. 313: 1192-202. PMID 17291495 DOI: 10.1016/j.yexcr.2006.12.027  0.56
2006 Gupta V, Wang W, Sosnowski BA, Hofman FM, Chen TC. Fibroblast growth factor-2-retargeted adenoviral vector for selective transduction of primary glioblastoma multiforme endothelial cells. Neurosurgical Focus. 20: E26. PMID 16709032  0.56
2006 Charalambous C, Chen TC, Hofman FM. Characteristics of tumor-associated endothelial cells derived from glioblastoma multiforme. Neurosurgical Focus. 20: E22. PMID 16709028 DOI: 10.3171/foc.2006.20.4.e22  0.56
2006 Gupta V, Su YS, Wang W, Kardosh A, Liebes LF, Hofman FM, Schönthal AH, Chen TC. Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin. Neurosurgical Focus. 20: E20. PMID 16709026 DOI: 10.3171/foc.2006.20.4.13  0.56
2006 Pyrko P, Soriano N, Kardosh A, Liu YT, Uddin J, Petasis NA, Hofman FM, Chen CS, Chen TC, Schönthal AH. Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo Molecular Cancer. 5. PMID 16707021 DOI: 10.1186/1476-4598-5-19  0.56
2006 Milan J, Charalambous C, Elhag R, Chen TC, Li W, Guan S, Hofman FM, Zidovetzki R. Multiple signaling pathways are involved in endothelin-1-induced brain endothelial cell migration. American Journal of Physiology. Cell Physiology. 291: C155-64. PMID 16452160 DOI: 10.1152/ajpcell.00239.2005  0.48
2005 Charalambous C, Pen LB, Su YS, Milan J, Chen TC, Hofman FM. Interleukin-8 differentially regulates migration of tumor-associated and normal human brain endothelial cells. Cancer Research. 65: 10347-54. PMID 16288024 DOI: 10.1158/0008-5472.CAN-05-0949  0.48
2005 Kardosh A, Soriano N, Liu YT, Uddin J, Petasis NA, Hofman FM, Chen TC, Schönthal AH. Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib Blood. 106: 4330-4338. PMID 16123214 DOI: 10.1182/blood-2005-07-2819  0.56
2005 Wu Z, Guo H, Chow N, Sallstrom J, Bell RD, Deane R, Brooks AI, Kanagala S, Rubio A, Sagare A, Liu D, Li F, Armstrong D, Gasiewicz T, Zidovetzki R, ... ... Hofman F, et al. Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease. Nature Medicine. 11: 959-65. PMID 16116430 DOI: 10.1038/nm1287  0.56
2005 Charalambous C, Hofman FM, Chen TC. Functional and phenotypic differences between glioblastoma multiforme-derived and normal human brain endothelial cells. Journal of Neurosurgery. 102: 699-705. PMID 15871513 DOI: 10.3171/jns.2005.102.4.0699  0.56
2005 Kardosh A, Wang W, Uddin J, Petasis NA, Hofman FM, Chen TC, Schönthal AH. Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo Cancer Biology and Therapy. 4: 571-582. PMID 15846081  0.56
2003 Wu Z, Hofman FM, Zlokovic BV. A simple method for isolation and characterization of mouse brain microvascular endothelial cells. Journal of Neuroscience Methods. 130: 53-63. PMID 14583404 DOI: 10.1016/S0165-0270(03)00206-1  0.56
2003 Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, ... ... Hofman F, et al. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nature Medicine. 9: 907-13. PMID 12808450 DOI: 10.1038/nm890  0.56
2002 Chen TC, Wadsten P, Su S, Rawlinson N, Hofman FM, Hill CK, Schönthal AH. The type IV phosphodiesterase inhibitor rolipram induces expression of the cell cycle inhibitors p21(Cip1) and p27(Kip1), resulting in growth inhibition, increased differentiation, and subsequent apoptosis of malignant A-172 glioma cells. Cancer Biology & Therapy. 1: 268-76. PMID 12432276  0.48
2002 Giri R, Selvaraj S, Miller CA, Hofman F, Yan SD, Stern D, Zlokovic BV, Kalra VK. Effect of endothelial cell polarity on beta-amyloid-induced migration of monocytes across normal and AD endothelium. American Journal of Physiology. Cell Physiology. 283: C895-904. PMID 12176746 DOI: 10.1152/ajpcell.00293.2001  0.56
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