David F. Wieczorek - Publications

Affiliations: 
Molecular Genetics, Biochemistry and Microbiology University of Cincinnati, Cincinnati, OH 
Area:
Molecular Biology, Genetics, Biochemistry, Physiology Biology

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Tarigopula M, Davis RT, Mungai PT, Ryba DM, Wieczorek DF, Cowan CL, Violin JD, Wolska BM, Solaro RJ. Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model. Cardiovascular Research. 107: 226-34. PMID 26045475 DOI: 10.1093/cvr/cvv162  0.92
2014 Prasad V, Lorenz JN, Lasko VM, Nieman ML, Jiang M, Gao X, Rubinstein J, Wieczorek DF, Shull GE. Ablation of plasma membrane Ca(2+)-ATPase isoform 4 prevents development of hypertrophy in a model of hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 77: 53-63. PMID 25280781 DOI: 10.1016/j.yjmcc.2014.09.025  0.92
2014 Simon JN, Chowdhury SA, Warren CM, Sadayappan S, Wieczorek DF, Solaro RJ, Wolska BM. Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation. Basic Research in Cardiology. 109: 445. PMID 25280528 DOI: 10.1007/s00395-014-0445-6  0.92
2014 Alves ML, Dias FA, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sadayappan S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circulation. Cardiovascular Genetics. 7: 132-43. PMID 24585742 DOI: 10.1161/CIRCGENETICS.113.000324  0.92
2014 Witayavanitkul N, Ait Mou Y, Kuster DW, Khairallah RJ, Sarkey J, Govindan S, Chen X, Ge Y, Rajan S, Wieczorek DF, Irving T, Westfall MV, de Tombe PP, Sadayappan S. Myocardial infarction-induced N-terminal fragment of cardiac myosin-binding protein C (cMyBP-C) impairs myofilament function in human myocardium. The Journal of Biological Chemistry. 289: 8818-27. PMID 24509847 DOI: 10.1074/jbc.M113.541128  0.92
2013 Schulz EM, Wilder T, Chowdhury SA, Sheikh HN, Wolska BM, Solaro RJ, Wieczorek DF. Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy. The Journal of Biological Chemistry. 288: 28925-35. PMID 23960072 DOI: 10.1074/jbc.M113.466466  0.92
2013 Rajan S, Pena JR, Jegga AG, Aronow BJ, Wolska BM, Wieczorek DF. Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout. Physiological Genomics. 45: 764-73. PMID 23800848 DOI: 10.1152/physiolgenomics.00023.2013  0.92
2013 Schulz EM, Wieczorek DF. Tropomyosin de-phosphorylation in the heart: what are the consequences? Journal of Muscle Research and Cell Motility. 34: 239-46. PMID 23793376 DOI: 10.1007/s10974-013-9348-7  0.92
2013 Yar S, Chowdhury SA, Davis RT, Kobayashi M, Monasky MM, Rajan S, Wolska BM, Gaponenko V, Kobayashi T, Wieczorek DF, Solaro RJ. Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L. The Journal of Biological Chemistry. 288: 16235-46. PMID 23609439 DOI: 10.1074/jbc.M113.458695  0.92
2013 Mamidi R, Mallampalli SL, Wieczorek DF, Chandra M. Identification of two new regions in the N-terminus of cardiac troponin T that have divergent effects on cardiac contractile function. The Journal of Physiology. 591: 1217-34. PMID 23207592 DOI: 10.1113/jphysiol.2012.243394  0.92
2012 Schulz EM, Correll RN, Sheikh HN, Lofrano-Alves MS, Engel PL, Newman G, Schultz JEJ, Molkentin JD, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin dephosphorylation results in compensated cardiac hypertrophy Journal of Biological Chemistry. 287: 44478-44489. PMID 23148217 DOI: 10.1074/jbc.M112.402040  0.92
2011 Gaffin RD, Peña JR, Alves MS, Dias FA, Chowdhury SA, Heinrich LS, Goldspink PH, Kranias EG, Wieczorek DF, Wolska BM. Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein. Journal of Molecular and Cellular Cardiology. 51: 812-20. PMID 21840315 DOI: 10.1016/j.yjmcc.2011.07.026  0.92
2011 Gaffin RD, Chowdhury SA, Alves MS, Dias FA, Ribeiro CT, Fogaca RT, Wieczorek DF, Wolska BM. Effects of nicotine administration in a mouse model of familial hypertrophic cardiomyopathy, α-tropomyosin D175N. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1646-55. PMID 21743000 DOI: 10.1152/ajpheart.00277.2010  0.92
2011 Karam CN, Warren CM, Rajan S, de Tombe PP, Wieczorek DF, Solaro RJ. Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation. Journal of Muscle Research and Cell Motility. 31: 315-22. PMID 21221740 DOI: 10.1007/s10974-010-9237-2  0.92
2011 Al Moamen NJ, Prasad V, Bodi I, Miller ML, Neiman ML, Lasko VM, Alper SL, Wieczorek DF, Lorenz JN, Shull GE. Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure. Journal of Molecular and Cellular Cardiology. 50: 137-46. PMID 21056571 DOI: 10.1016/j.yjmcc.2010.10.028  0.92
2011 Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM. Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis. Journal of Molecular and Cellular Cardiology. 50: 442-50. PMID 21047515 DOI: 10.1016/j.yjmcc.2010.10.032  0.92
2010 Peña JR, Szkudlarek AC, Warren CM, Heinrich LS, Gaffin RD, Jagatheesan G, del Monte F, Hajjar RJ, Goldspink PH, Solaro RJ, Wieczorek DF, Wolska BM. Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 49: 993-1002. PMID 20854827 DOI: 10.1016/j.yjmcc.2010.09.010  0.92
2010 Thomas A, Rajan S, Thurston HL, Masineni SN, Dube P, Bose A, Muthu V, Dube S, Wieczorek DF, Poiesz BJ, Dube DK. Expression of a novel tropomyosin isoform in axolotl heart and skeletal muscle. Journal of Cellular Biochemistry. 110: 875-81. PMID 20564186 DOI: 10.1002/jcb.22599  0.92
2010 Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, ... ... Wieczorek DF, et al. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation. 121: 410-8. PMID 20065163 DOI: 10.1161/CIRCULATIONAHA.109.889725  0.92
2009 Jagatheesan G, Rajan S, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Wang T, Wang YG, Ashraf M, Liggett SB, Lorenz J, Solaro RJ, Wieczorek DF. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity. American Journal of Physiology. Heart and Circulatory Physiology. 297: H181-90. PMID 19429821 DOI: 10.1152/ajpheart.00329.2008  0.92
2008 Warren CM, Arteaga GM, Rajan S, Ahmed RP, Wieczorek DF, Solaro RJ. Use of 2-D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy. Proteomics. 8: 100-5. PMID 18095372 DOI: 10.1002/pmic.200700772  0.92
2007 Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga GM, Solaro RJ, Liggett SB, Wieczorek DF. Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis. American Journal of Physiology. Heart and Circulatory Physiology. 293: H949-58. PMID 17416600 DOI: 10.1152/ajpheart.01341.2006  0.92
2006 Rajan S, Williams SS, Jagatheesan G, Ahmed RP, Fuller-Bicer G, Schwartz A, Aronow BJ, Wieczorek DF. Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophy. Physiological Genomics. 27: 309-17. PMID 16882888 DOI: 10.1152/physiolgenomics.00072.2006  0.92
2005 Zajdel RW, Denz CR, McLean MD, Dube S, Muthuchamy M, Poiesz BJ, Wieczorek DF, Dube DK. Diminished myofibril organization in mutant axolotl hearts transfected with site-directed mutants of sarcomeric tropomyosins. Cardiovascular Toxicology. 5: 75-90. PMID 15738587  0.92
2004 Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga G, de Tombe PP, Solaro RJ, Wieczorek DF. Physiological significance of troponin T binding domains in striated muscle tropomyosin. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1484-94. PMID 15191887 DOI: 10.1152/ajpheart.01112.2003  0.92
2003 Prabhakar R, Petrashevskaya N, Schwartz A, Aronow B, Boivin GP, Molkentin JD, Wieczorek DF. A mouse model of familial hypertrophic cardiomyopathy caused by a alpha-tropomyosin mutation. Molecular and Cellular Biochemistry. 251: 33-42. PMID 14575301 DOI: 10.1023/A:1025409227350  0.92
2003 Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Vahebi S, DeTombe P, Solaro RJ, Labitzke E, Hilliard G, Wieczorek DF. Functional importance of the carboxyl-terminal region of striated muscle tropomyosin. The Journal of Biological Chemistry. 278: 23204-11. PMID 12690096 DOI: 10.1074/jbc.M303073200  0.92
2002 Pieples K, Arteaga G, Solaro RJ, Grupp I, Lorenz JN, Boivin GP, Jagatheesan G, Labitzke E, DeTombe PP, Konhilas JP, Irving TC, Wieczorek DF. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1344-53. PMID 12234784 DOI: 10.1152/ajpheart.00351.2002  0.92
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