Charles Midgett, Ph.D. - Related publications

Affiliations: 
2009 Biochemistry Dartmouth College, Hanover, NH, United States 
Area:
Biochemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Ramesh S, Park S, Call MJ, Im W, Call ME. Experimentally Guided Computational Methods Yield Highly Accurate Insights into Transmembrane Interactions within the T Cell Receptor Complex. The Journal of Physical Chemistry. B. PMID 33030343 DOI: 10.1021/acs.jpcb.0c06403   
2020 Jones EM, Lubock NB, Venkatakrishnan AJ, Wang J, Tseng AM, Paggi JM, Latorraca NR, Cancilla D, Satyadi M, Davis JE, Babu MM, Dror RO, Kosuri S. Structural and functional characterization of G protein-coupled receptors with deep mutational scanning. Elife. 9. PMID 33084570 DOI: 10.7554/eLife.54895   
2020 Ye N, Qin W, Tian S, Xu Q, Wold EA, Zhou J, Zhen XC. Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases. Journal of Medicinal Chemistry. PMID 33111525 DOI: 10.1021/acs.jmedchem.0c01192   
2020 Wang H, Hyoung Lee J, Wang Y, Seo HS, Wang J, Deshane JS, Ponnazhagan S. A conserved aromatic moiety in the ectodomain is a key determinant for structural integrity and protein trafficking of TNFR superfamily. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 33047892 DOI: 10.1096/fj.202000341R   
2020 Pollok S, Reiner A. Subunit-selective iGluR antagonists can potentiate heteromeric receptor responses by blocking desensitization. Proceedings of the National Academy of Sciences of the United States of America. 117: 25851-25858. PMID 32999066 DOI: 10.1073/pnas.2007471117   
2020 Kim JH, Marton J, Ametamey SM, Cumming P. A Review of Molecular Imaging of Glutamate Receptors. Molecules (Basel, Switzerland). 25. PMID 33081223 DOI: 10.3390/molecules25204749   
2020 Pandey S, Saha S, Shukla AK. Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex. Molecular Cell. 80: 3-5. PMID 33007256 DOI: 10.1016/j.molcel.2020.09.016   
2020 Pandey S, Saha S, Shukla AK. Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex. Molecular Cell. 80: 3-5. PMID 33007256 DOI: 10.1016/j.molcel.2020.09.016   
2020 Yang LK, Tao YX. Alanine Scanning Mutagenesis of the DRYxxI Motif and Intracellular Loop 2 of Human Melanocortin-4 Receptor. International Journal of Molecular Sciences. 21. PMID 33076233 DOI: 10.3390/ijms21207611   
2020 Rajan R, Schepmann D, Schreiber JA, Seebohm G, Wünsch B. Synthesis of GluN2A-selective NMDA receptor antagonists with an electron-rich aromatic B-ring. European Journal of Medicinal Chemistry. 112939. PMID 33162207 DOI: 10.1016/j.ejmech.2020.112939   
2020 Işbilir A, Möller J, Arimont M, Bobkov V, Perpiñá-Viciano C, Hoffmann C, Inoue A, Heukers R, de Graaf C, Smit MJ, Annibale P, Lohse MJ. Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists. Proceedings of the National Academy of Sciences of the United States of America. PMID 33148803 DOI: 10.1073/pnas.2013319117   
2020 Lemoine D, Mondoloni S, Tange J, Lambolez B, Faure P, Taly A, Tricoire L, Mourot A. Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology. Elife. 9. PMID 33112237 DOI: 10.7554/eLife.59026   
2020 Liu YP, Wu X, Meng JH, Yao J, Wang BJ. Functional Analysis of the 3' Untranslated Region of the Human Gene in Regulating Gene Expression in vitro. Neuropsychiatric Disease and Treatment. 16: 2361-2370. PMID 33116535 DOI: 10.2147/NDT.S268753   
2020 Li M, Huang C, Wu X, Ding F, Hu Z, Zhu Y, Zhao L, Hou L, Chen H, Wang H, Xu J, Tang D. The optimization of a novel selective antagonist for human M muscarinic acetylcholine receptor. Bioorganic & Medicinal Chemistry Letters. 30: 127632. PMID 33132116 DOI: 10.1016/j.bmcl.2020.127632   
2020 Illes P, Müller CE, Jacobson KA, Grutter T, Nicke A, Fountain SJ, Kennedy C, Schmalzing G, Jarvis MF, Stojilkovic SS, King BF, Di Virgilio F. Update of P2X receptor properties and their pharmacology: IUPHAR Review 30. British Journal of Pharmacology. PMID 33125712 DOI: 10.1111/bph.15299   
2020 Chen J, Cai X, Yan M, Wang Z, Lv Z, Wang C. A method for identifying G protein-coupled receptor dimers and their interfaces. Biochimica Et Biophysica Acta. Molecular Cell Research. 118887. PMID 33075383 DOI: 10.1016/j.bbamcr.2020.118887   
2020 Norel X, Sugimoto Y, Ozen G, Abdelazeem H, Amgoud Y, Bouhadoun A, Bassiouni W, Goepp M, Mani S, Manikpurage HD, Senbel A, Longrois D, Heinemann A, Yao C, Clapp LH. International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions. Pharmacological Reviews. 72: 910-968. PMID 32962984 DOI: 10.1124/pr.120.019331   
2020 Leung SW. The vascular impact of IP-TP receptor interactions. Acta Physiologica (Oxford, England). e13577. PMID 33135294 DOI: 10.1111/apha.13577   
2020 Childs MD, Luyt LG. A Decade's Progress in the Development of Molecular Imaging Agents Targeting the Growth Hormone Secretagogue Receptor. Molecular Imaging. 19: 1536012120952623. PMID 33104445 DOI: 10.1177/1536012120952623   
2020 Haspula D, Clark MA. Cannabinoid Receptors: An Update on Cell Signaling, Pathophysiological Roles and Therapeutic Opportunities in Neurological, Cardiovascular, and Inflammatory Diseases. International Journal of Molecular Sciences. 21. PMID 33080916 DOI: 10.3390/ijms21207693   
2020 Gan Z, Cheng J, Chen S, Hou J, Li N, Xia H, Xia L, Lu Y, Nie P. Identification and characterization of tilapia CRFB1, CRFB2 and CRFB5 reveals preferential receptor usage of three IFN subtypes in perciform fishes. Fish & Shellfish Immunology. PMID 33011433 DOI: 10.1016/j.fsi.2020.10.002   
2020 Yeliseev A, van den Berg A, Zoubak L, Hines K, Stepnowski S, Williston K, Yan W, Gawrisch K, Zmuda J. Thermostability of a recombinant G protein-coupled receptor expressed at high level in mammalian cell culture. Scientific Reports. 10: 16805. PMID 33033368 DOI: 10.1038/s41598-020-73813-7   
2020 Bernhard M, Laube B. Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs. Scientific Reports. 10: 16569. PMID 33024136 DOI: 10.1038/s41598-020-73157-2   
2020 Pressly B, Lee RD, Barnych B, Hammock BD, Wulff H. Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in the Pore of the α2β3γ2 GABA-A Receptor. Molecular Pharmacology. PMID 33109687 DOI: 10.1124/molpharm.120.000090   
2020 Yuan C, Ni L, Zhang C, Wu X. The Role of Notch3 Signaling in Kidney Disease. Oxidative Medicine and Cellular Longevity. 2020: 1809408. PMID 33149805 DOI: 10.1155/2020/1809408   
2020 Reeh K, Summers PA, Gould IR, Woscholski R, Vilar R. Design, synthesis and evaluation of a tripodal receptor for phosphatidylinositol phosphates. Scientific Reports. 10: 18450. PMID 33116198 DOI: 10.1038/s41598-020-75484-w   
2020 Navarro G, Gonzalez A, Campanacci S, Rivas-Santisteban R, Reyes-Resina I, Casajuana-Martin N, Cordomí A, Pardo L, Franco R. Experimental and computational analysis of biased agonism on full-length and a C-terminally truncated adenosine A receptor. Computational and Structural Biotechnology Journal. 18: 2723-2732. PMID 33101610 DOI: 10.1016/j.csbj.2020.09.028   
2020 Marti-Solano M, Crilly SE, Malinverni D, Munk C, Harris M, Pearce A, Quon T, Mackenzie AE, Wang X, Peng J, Tobin AB, Ladds G, Milligan G, Gloriam DE, Puthenveedu MA, et al. Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature. PMID 33149304 DOI: 10.1038/s41586-020-2888-2   
2020 Watabe M, Yoshimura H, Arjunan SNV, Kaizu K, Takahashi K. Signaling activations through G-protein-coupled-receptor aggregations. Physical Review. E. 102: 032413. PMID 33076007 DOI: 10.1103/PhysRevE.102.032413   
2020 Lucianò AM, Tata AM. Functional Characterization of Cholinergic Receptors in Melanoma Cells. Cancers. 12. PMID 33120929 DOI: 10.3390/cancers12113141   
2020 Gunera J, Baker JG, van Hilten N, Rosenbaum DM, Kolb P. Structure-Based Discovery of Novel Ligands for the Orexin 2 Receptor. Journal of Medicinal Chemistry. PMID 32977721 DOI: 10.1021/acs.jmedchem.0c00964   
2020 Esteoulle L, Daubeuf F, Collot M, Riché S, Durroux T, Brasse D, Marchand P, Karpenko IA, Klymchenko AS, Bonnet D. A near-infrared fluorogenic dimer enables background-free imaging of endogenous GPCRs in living mice. Chemical Science. 11: 6824-6829. PMID 33033597 DOI: 10.1039/d0sc01018a   
2020 Kurtz R, Steinberg LG, Betcher M, Fowler D, Shepard BD. The Sensing Liver: Localization and Ligands for Hepatic Murine Olfactory and Taste Receptors. Frontiers in Physiology. 11: 574082. PMID 33123030 DOI: 10.3389/fphys.2020.574082   
2020 Scherbaum I, Heidecke H, Bunte K, Peters U, Beikler T, Boege F. Autoantibodies against M-muscarinic and beta-adrenergic receptors in periodontitis patients. Aging. 12: 16609-16620. PMID 32857064 DOI: 10.18632/aging.103864   
2020 Calderón-Zamora L, Canizalez-Román A, León-Sicairos N, Aguilera-Mendez A, Huang F, Hong E, Villafaña S. Changes in expression of orphan receptors GPR99 and GPR107 during the development and establishment of hypertension in spontaneously hypertensive rats. Journal of Receptor and Signal Transduction Research. 1-8. PMID 33121311 DOI: 10.1080/10799893.2020.1835959   
2020 Bhattarai A, Pawnikar S, Miao Y. Mechanism of ligand recognition by human ACE2 receptor. Biorxiv : the Preprint Server For Biology. PMID 33140043 DOI: 10.1101/2020.10.30.362749   
2020 Jakubík J, Randáková A, Chetverikov N, El-Fakahany EE, Doležal V. The operational model of allosteric modulation of pharmacological agonism. Scientific Reports. 10: 14421. PMID 32879329 DOI: 10.1038/s41598-020-71228-y   
2020 Turk LS, Mitchell D, Comoletti D. Purification of a heterodimeric Reelin construct to investigate binding stoichiometry. European Biophysics Journal : Ebj. PMID 33057791 DOI: 10.1007/s00249-020-01465-6   
2020 Buñay J, Fouache A, Trousson A, de Joussineau C, Bouchareb E, Zhekun Z, Kocer A, Morel L, Baron S, Lobaccaro JMA. Screening for Liver X Receptor modulators: where are we and for what use? British Journal of Pharmacology. PMID 33080050 DOI: 10.1111/bph.15286   
2020 Pieterse L, van der Walt MM, Terre'Blanche G. C2-substituted quinazolinone derivatives exhibit A and/or A adenosine receptor affinities in the low micromolar range. Bioorganic & Medicinal Chemistry Letters. 30: 127274. PMID 32631506 DOI: 10.1016/j.bmcl.2020.127274   
2020 Conte G, Nguyen NT, Alves M, de Diego-Garcia L, Kenny A, Nicke A, Henshall DC, Jimenez-Mateos EM, Engel T. P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice. Frontiers in Molecular Neuroscience. 13: 127. PMID 32982684 DOI: 10.3389/fnmol.2020.00127   
2020 King BF. Burnstock and the legacy of the inhibitory junction potential and P2Y1 receptors. Purinergic Signalling. PMID 33125617 DOI: 10.1007/s11302-020-09747-6   
2020 Heeney A, Rogers AC, Mohan H, Mc Dermott F, Baird AW, Winter DC. Prostaglandin E receptors and their role in gastrointestinal motility - Potential therapeutic targets. Prostaglandins & Other Lipid Mediators. 152: 106499. PMID 33035691 DOI: 10.1016/j.prostaglandins.2020.106499   
2020 Wagner N, Wagner KD. The Role of PPARs in Disease. Cells. 9. PMID 33126411 DOI: 10.3390/cells9112367   
2020 Fu TT, Tu G, Ping M, Zheng GX, Yang FY, Yang JY, Zhang Y, Yao XJ, Xue WW, Zhu F. Subtype-selective mechanisms of negative allosteric modulators binding to group I metabotropic glutamate receptors. Acta Pharmacologica Sinica. PMID 33122823 DOI: 10.1038/s41401-020-00541-z   
2020 Holze J, Bermudez M, Pfeil EM, Kauk M, Bödefeld T, Irmen M, Matera C, Dallanoce C, De Amici M, Holzgrabe U, König GM, Tränkle C, Wolber G, Schrage R, Mohr K, et al. Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling. Acs Pharmacology & Translational Science. 3: 859-867. PMID 33073186 DOI: 10.1021/acsptsci.0c00069   
2020 Miranda AS, Marcos PM, Ascenso JR, Berberan-Santos MN, Schurhammer R, Hickey N, Geremia S. Dihomooxacalix[4]arene-Based Fluorescent Receptors for Anion and Organic Ion Pair Recognition. Molecules (Basel, Switzerland). 25. PMID 33066580 DOI: 10.3390/molecules25204708   
2020 Devenish SO, Winters BL, Anderson LL, Arnold JC, McGregor IS, Vaughan CW, Chebib M, Absalom NL. The anticonvulsant zonisamide positively modulates recombinant and native glycine receptors at clinically relevant concentrations. Neuropharmacology. 108371. PMID 33122032 DOI: 10.1016/j.neuropharm.2020.108371   
2020 Singh N, Villoutreix BO. Demystifying the Molecular Basis of Pyrazoloquinolinones Recognition at the Extracellular α1+/β3- Interface of the GABA Receptor by Molecular Modeling. Frontiers in Pharmacology. 11: 561834. PMID 33041802 DOI: 10.3389/fphar.2020.561834   
2020 Dvořák Z, Sokol H, Mani S. Drug Mimicry: Promiscuous Receptors PXR and AhR, and Microbial Metabolite Interactions in the Intestine. Trends in Pharmacological Sciences. PMID 33097284 DOI: 10.1016/j.tips.2020.09.013