Year |
Citation |
Score |
2023 |
McFadden MJ, Reynolds MB, Michmerhuizen BC, Anderson FM, O'Riordan MXD, O'Meara TR. Non-canonical activation of IRE1α during infection enhances macrophage fungicidal activity. Biorxiv : the Preprint Server For Biology. PMID 37873171 DOI: 10.1101/2023.10.02.560560 |
0.786 |
|
2023 |
Santana DJ, Anku JAE, Zhao G, Zarnowski R, Johnson CJ, Hautau H, Visser ND, Ibrahim AS, Andes D, Nett JE, Singh S, O'Meara TR. A -specific adhesin, Scf1 governs surface association, colonization, and virulence. Science (New York, N.Y.). 381: 1461-1467. PMID 37769084 DOI: 10.1126/science.adf8972 |
0.758 |
|
2023 |
Metzner K, O'Meara MJ, Halligan B, Wotring JW, Sexton JZ, O'Meara TR. Imaging-Based Screening Identifies Modulators of the Translation Initiation Factor Complex in Candida albicans. Antimicrobial Agents and Chemotherapy. 67: e0050323. PMID 37382550 DOI: 10.1128/aac.00503-23 |
0.322 |
|
2023 |
Anderson FM, Visser ND, Amses KR, Hodgins-Davis A, Weber AM, Metzner KM, McFadden MJ, Mills RE, O'Meara MJ, James TY, O'Meara TR. Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease. Plos Biology. 21: e3001822. PMID 37205709 DOI: 10.1371/journal.pbio.3001822 |
0.803 |
|
2022 |
Santana DJ, O'Meara TR. Author Correction: Forward and reverse genetic dissection of morphogenesis identifies filament-competent Candida auris strains. Nature Communications. 13: 1089. PMID 35197465 DOI: 10.1038/s41467-022-28739-1 |
0.744 |
|
2021 |
Santana DJ, O'Meara TR. Forward and reverse genetic dissection of morphogenesis identifies filament-competent Candida auris strains. Nature Communications. 12: 7197. PMID 34893621 DOI: 10.1038/s41467-021-27545-5 |
0.779 |
|
2021 |
Fu C, Zhang X, Veri AO, Iyer KR, Lash E, Xue A, Yan H, Revie NM, Wong C, Lin ZY, Polvi EJ, Liston SD, VanderSluis B, Hou J, Yashiroda Y, et al. Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets. Nature Communications. 12: 6497. PMID 34764269 DOI: 10.1038/s41467-021-26850-3 |
0.739 |
|
2021 |
MacAlpine J, Daniel-Ivad M, Liu Z, Yano J, Revie NM, Todd RT, Stogios PJ, Sanchez H, O'Meara TR, Tompkins TA, Savchenko A, Selmecki A, Veri AO, Andes DR, Fidel PL, et al. A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase. Nature Communications. 12: 6151. PMID 34686660 DOI: 10.1038/s41467-021-26390-w |
0.78 |
|
2021 |
Case NT, Duah K, Larsen B, Wong CJ, Gingras AC, O'Meara TR, Robbins N, Veri AO, Whitesell L, Cowen LE. The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans. Cell Reports. 36: 109584. PMID 34433036 DOI: 10.1016/j.celrep.2021.109584 |
0.781 |
|
2021 |
Ost KS, O'Meara TR, Stephens WZ, Chiaro T, Zhou H, Penman J, Bell R, Catanzaro JR, Song D, Singh S, Call DH, Hwang-Wong E, Hanson KE, Valentine JF, Christensen KA, et al. Adaptive immunity induces mutualism between commensal eukaryotes. Nature. PMID 34262174 DOI: 10.1038/s41586-021-03722-w |
0.796 |
|
2021 |
Hossain S, Veri AO, Liu Z, Iyer KR, O'Meara TR, Robbins N, Cowen LE. Mitochondrial perturbation reduces susceptibility to xenobiotics through altered efflux in Candida albicans. Genetics. PMID 34143207 DOI: 10.1093/genetics/iyab095 |
0.739 |
|
2020 |
Santana DJ, Anderson FM, O'Meara TR. Monitoring Inflammasome Priming and Activation in Response to Candida albicans. Current Protocols in Microbiology. 59: e124. PMID 33108055 DOI: 10.1002/cpmc.124 |
0.772 |
|
2020 |
Hodgins-Davis A, O'Meara TR. Systems biology of host-Candida interactions: understanding how we shape each other. Current Opinion in Microbiology. 58: 1-7. PMID 32485592 DOI: 10.1016/j.mib.2020.04.001 |
0.311 |
|
2019 |
Pourhaghighi R, O'Meara TR, Cowen LE, Emili A. Protein-Protein Interaction Profiling in Candida albicans Revealed by Biochemical Purification-Mass Spectrometry (BP/MS). Methods in Molecular Biology (Clifton, N.J.). 2049: 203-211. PMID 31602613 DOI: 10.1007/978-1-4939-9736-7_12 |
0.517 |
|
2019 |
O'Meara TR, O'Meara MJ, Polvi EJ, Pourhaghighi MR, Liston SD, Lin ZY, Veri AO, Emili A, Gingras AC, Cowen LE. Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen. Plos Biology. 17: e3000358. PMID 31283755 DOI: 10.1371/Journal.Pbio.3000358 |
0.778 |
|
2019 |
Brimacombe CA, Burke JE, Parsa JY, Catania S, O'Meara TR, Witchley JN, Burrack LS, Madhani HD, Noble SM. A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans. Plos Biology. 17: e3000331. PMID 31226107 DOI: 10.1371/Journal.Pbio.3000331 |
0.693 |
|
2018 |
O'Meara TR, Cowen LE. Insights into the host-pathogen interaction: manipulation of macrophage pyroptosis. Microbial Cell (Graz, Austria). 5: 566-568. PMID 30533421 DOI: 10.15698/Mic2018.12.662 |
0.649 |
|
2018 |
O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, et al. High-Throughput Screening Identifies Genes Required for Induction of Macrophage Pyroptosis. Mbio. 9. PMID 30131363 DOI: 10.1128/Mbio.01581-18 |
0.782 |
|
2018 |
Veri AO, Miao Z, Shapiro RS, Tebbji F, O'Meara TR, Kim SH, Colazo J, Tan K, Vyas VK, Whiteway M, Robbins N, Wong KH, Cowen LE. Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. Plos Genetics. 14: e1007270. PMID 29590106 DOI: 10.1371/Journal.Pgen.1007270 |
0.779 |
|
2018 |
Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling formation of microbiostatic frustrated phagosomes. Elife. 7. PMID 29553370 DOI: 10.7554/Elife.34798 |
0.567 |
|
2018 |
Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S. Author response: Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes Elife. DOI: 10.7554/Elife.34798.042 |
0.535 |
|
2017 |
O'Meara TR, Robbins N, Cowen LE. The Hsp90 Chaperone Network Modulates Candida Virulence Traits. Trends in Microbiology. PMID 28549824 DOI: 10.1016/J.Tim.2017.05.003 |
0.727 |
|
2017 |
Xie JL, O'Meara TR, Polvi EJ, Robbins N, Cowen LE. Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A. Msphere. 2. PMID 28261668 DOI: 10.1128/mSphere.00056-17 |
0.775 |
|
2016 |
Li X, Robbins N, O'Meara TR, Cowen LE. Extensive Functional Redundancy in the Regulation of Candida albicans Drug Resistance and Morphogenesis by Lysine Deacetylases Hos2, Hda1, Rpd3, and Rpd31. Molecular Microbiology. PMID 27868254 DOI: 10.1111/Mmi.13578 |
0.738 |
|
2016 |
O'Meara TR, Veri AO, Polvi EJ, Li X, Valaei SF, Diezmann S, Cowen LE. Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress. Plos Genetics. 12: e1006142. PMID 27341673 DOI: 10.1371/Journal.Pgen.1006142 |
0.625 |
|
2015 |
Ost KS, O'Meara TR, Huda N, Esher SK, Alspaugh JA. The Cryptococcus neoformans alkaline response pathway: identification of a novel rim pathway activator. Plos Genetics. 11: e1005159. PMID 25859664 DOI: 10.1371/Journal.Pgen.1005159 |
0.771 |
|
2015 |
O'Meara TR, Veri AO, Ketela T, Jiang B, Roemer T, Cowen LE. Global analysis of fungal morphology exposes mechanisms of host cell escape. Nature Communications. 6: 6741. PMID 25824284 DOI: 10.1038/Ncomms7741 |
0.688 |
|
2015 |
Polvi EJ, Li X, O'Meara TR, Leach MD, Cowen LE. Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies. Cellular and Molecular Life Sciences : Cmls. 72: 2261-87. PMID 25700837 DOI: 10.1007/S00018-015-1860-Z |
0.626 |
|
2015 |
Hill JA, O'Meara TR, Cowen LE. Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations. Cell Reports. PMID 25660029 DOI: 10.1016/J.Celrep.2015.01.009 |
0.657 |
|
2014 |
O'Meara TR, Cowen LE. Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence. Cellular Microbiology. 16: 473-81. PMID 24438186 DOI: 10.1111/Cmi.12266 |
0.674 |
|
2014 |
O'Meara TR, Xu W, Selvig KM, O'Meara MJ, Mitchell AP, Alspaugh JA. The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host. Molecular and Cellular Biology. 34: 673-84. PMID 24324006 DOI: 10.1128/Mcb.01359-13 |
0.509 |
|
2013 |
O'Meara TR, Holmer SM, Selvig K, Dietrich F, Alspaugh JA. Cryptococcus neoformans Rim101 is associated with cell wall remodeling and evasion of the host immune responses. Mbio. 4. PMID 23322637 DOI: 10.1128/Mbio.00522-12 |
0.507 |
|
2012 |
O'Meara TR, Alspaugh JA. The Cryptococcus neoformans capsule: a sword and a shield. Clinical Microbiology Reviews. 25: 387-408. PMID 22763631 DOI: 10.1128/Cmr.00001-12 |
0.498 |
|
2011 |
Okagaki LH, Wang Y, Ballou ER, O'Meara TR, Bahn YS, Alspaugh JA, Xue C, Nielsen K. Cryptococcal titan cell formation is regulated by G-protein signaling in response to multiple stimuli. Eukaryotic Cell. 10: 1306-16. PMID 21821718 DOI: 10.1128/Ec.05179-11 |
0.722 |
|
2010 |
O'Meara TR, Hay C, Price MS, Giles S, Alspaugh JA. Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host. Eukaryotic Cell. 9: 1193-202. PMID 20581290 DOI: 10.1128/Ec.00098-10 |
0.464 |
|
2010 |
O'Meara TR, Norton D, Price MS, Hay C, Clements MF, Nichols CB, Alspaugh JA. Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule. Plos Pathogens. 6: e1000776. PMID 20174553 DOI: 10.1371/Journal.Ppat.1000776 |
0.505 |
|
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